Genomes and Genes
Summary: The muscular membranous segment between the PHARYNX and the STOMACH in the UPPER GASTROINTESTINAL TRACT.
Publications247 found, 100 shown here
- In vivo histology of Barrett's esophagus and associated neoplasia by confocal laser endomicroscopyRalf Kiesslich
Medical Clinic, Johannes Gutenberg University Mainz, Germany
Clin Gastroenterol Hepatol 4:979-87. 2006..Here, we have applied this technique to the in vivo diagnosis of Barrett's epithelium and associated neoplasia...
- Probe-based confocal laser endomicroscopy compared with standard four-quadrant biopsy for evaluation of neoplasia in Barrett's esophagusM Bajbouj
II Medizinische Klinik und Poliklinik, Klinikum rechts der Isar, Technische Universitat Munchen, Germany
Endoscopy 42:435-40. 2010Surveillance of Barrett's esophagus includes endoscopic inspection with biopsy of suspicious lesions followed by four-quadrant biopsy of the remaining mucosa...
- Confocal laser scanning fluorescence microscopy for in vivo determination of microvessel density in Barrett's esophagusV Becker
Department of Medicine II, Technical University of Munich, Munich, Germany
Endoscopy 40:888-91. 2008Angiogenesis has been reported to be an essential step in the progression of cancers arising from Barrett's esophagus. Confocal laser scanning microscopy (CLM) has the potential to perform in vivo microscopy to detect angiogenesis and ..
- Etiology and pathogenesis of achalasia: the current understandingWoosuk Park
Department of Gastroenterology and Hepatology, Center for Swallowing and Esophageal Disorders, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Am J Gastroenterol 100:1404-14. 2005..Current evidence suggests that the initial insult to the esophagus, perhaps a viral infection or some other environmental factor, results in myenteric plexus inflammation...
- Activation of the interleukin-6/STAT3 antiapoptotic pathway in esophageal cells by bile acids and low pH: relevance to barrett's esophagusKaterina Dvorak
Department of Cell Biology and Anatomy, College of Medicine, The University of Arizona, Tucson, Arizona 85724, USA
Clin Cancer Res 13:5305-13. 2007The molecular factors contributing to the development of Barrett's esophagus (BE) are unclear...
- Preliminary accuracy and interobserver agreement for the detection of intraepithelial neoplasia in Barrett's esophagus with probe-based confocal laser endomicroscopyMichael B Wallace
Department of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida 32224, USA
Gastrointest Endosc 72:19-24. 2010..Confocal laser endomicroscopy (CLE) is a rapidly emerging method for in vivo imaging of the GI tract...
- History, molecular mechanisms, and endoscopic treatment of Barrett's esophagusStuart Jon Spechler
VA North Texas Healthcare System and the University of Texas Southwestern Medical Center, Dallas, Texas, USA
Gastroenterology 138:854-69. 2010..Association Institute's medical position statement and technical review on the management of Barrett's esophagus, which will be published in the near future...
- Remote magnetic manipulation of a wireless capsule endoscope in the esophagus and stomach of humans (with videos)Paul Swain
Department of Biosurgery and Surgical Technology, Imperial College and London University, 41 Willow Road, London, NW3 1TN United Kingdom
Gastrointest Endosc 71:1290-3. 2010..Remote manipulation of wireless capsule endoscopes might improve diagnostic accuracy and facilitate therapy...
- Assessment of experimental pain from skin, muscle, and esophagus in patients with chronic pancreatitisGeorg Dimcevski
Department of Medical Gastroenterology, Haukeland University Hospital, Bergen, Norway
Pancreas 35:22-9. 2007..We, therefore, aimed at exploring the pain mechanisms in chronic pancreatitis (CP) using a multimodal and multitissue stimulation approach...
- Cdx2 as a marker of epithelial intestinal differentiation in the esophagusRoy W Phillips
Department of Pathology, University of Virginia Medical Center, Charlottesville, VA 22908 0214, USA
Am J Surg Pathol 27:1442-7. 2003The histologic diagnosis of Barrett's esophagus requires the presence of goblet cells, but this finding may not be the earliest indicator of intestinal metaplasia...
- Induction of intestinalization in human esophageal keratinocytes is a multistep processJianping Kong
Department of Medicine, Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA 19104, USA
Carcinogenesis 30:122-30. 2009Barrett's esophagus (BE) is the replacement of normal squamous esophageal mucosa with an intestinalized columnar epithelium. The molecular mechanisms underlying its development are not understood...
- MicroRNA-196a is a potential marker of progression during Barrett's metaplasia-dysplasia-invasive adenocarcinoma sequence in esophagusDipen M Maru
Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA
Am J Pathol 174:1940-8. 2009Barrett's esophagus (BE)/Barrett's metaplasia (BM) is a recognized precursor of esophageal adenocarcinoma (EA) with an intermediary stage of dysplasia...
- Radiofrequency ablation in Barrett's esophagus with dysplasiaNicholas J Shaheen
Center for Esophageal Diseases and Swallowing, University of North Carolina School of Medicine, CB 7080, Chapel Hill, NC 27599 7080, USA
N Engl J Med 360:2277-88. 2009Barrett's esophagus, a condition of intestinal metaplasia of the esophagus, is associated with an increased risk of esophageal adenocarcinoma...
- Morphogenesis of the trachea and esophagus: current players and new roles for noggin and BmpsJianwen Que
Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
Differentiation 74:422-37. 2006..folding of the endoderm into a foregut tube, and the subsequent separation of the foregut tube into trachea and esophagus. Defects in foregut morphogenesis underlie the constellation of human birth defects known as esophageal atresia (..
- Bacterial biota in the human distal esophagusZhiheng Pei
Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
Proc Natl Acad Sci U S A 101:4250-5. 2004The esophagus, like other luminal organs of the digestive system, provides a potential environment for bacterial colonization, but little is known about the presence of a bacterial biota or its nature...
- High-resolution manometry predicts the success of oesophageal bolus transport and identifies clinically important abnormalities not detected by conventional manometryM Fox
Department of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland
Neurogastroenterol Motil 16:533-42. 2004..ii) The clinical value of HRM was assessed in a series of patients with endoscopy-negative dysphagia in whom conventional investigations had been non-diagnostic...
- Achalasia: a new clinically relevant classification by high-resolution manometryJohn E Pandolfino
Northwestern University, The Feinberg School of Medicine, Department of Medicine, Chicago, Illinois, USA
Gastroenterology 135:1526-33. 2008..This study aimed to compare the clinical characteristics and treatment response of these 3 subtypes...
- Treatment of eosinophilic esophagitis with specific food elimination diet directed by a combination of skin prick and patch testsJonathan M Spergel
Division of Allergy and Immunology, The Children s Hospital of Philadelphia, Pennsylvania 19104 4399, USA
Ann Allergy Asthma Immunol 95:336-43. 2005..Therapies have included corticosteroids, elemental diet, and diet restriction. We report our experience with skin prick and atopy patch testing and food elimination diets in patients diagnosed as having EE...
- Long-term clinical and pathologic response of Barrett's esophagus after antireflux surgeryPatrick J Byrne
University Department of Surgery, Trinity Centre for Health Sciences, St. James's Hospital, Dublin 8, Ireland
Am J Surg 188:27-33. 2004BACKGROUND: The impact of antireflux surgery on outcome in Barrett's esophagus, in particular its effect on both the regression of metaplasia and the progression of metaplasia through dysplasia to adenocarcinoma, remains unclear...
- Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2Nan Gao
Department of Genetics, and Institute for Diabetes, Obesity and Metabolism, University of Pennsylvania, Philadelphia, PA 19104, USA
Dev Cell 16:588-99. 2009..We conclude that Cdx2 controls important aspects of intestinal identity and development, and that this function is largely independent of the enteric Hox code...
- Life isn't flat: taking cancer biology to the next dimensionKeiran S M Smalley
The Wistar Institute, Philadelphia, Pennsylvania 19104, USA
In Vitro Cell Dev Biol Anim 42:242-7. 2006..It is likely that the adoption of these and other 3D models will allow us to more closely re-create the behavior of the tumor in vivo which may lead to identifying better anticancer drug candidates at an earlier stage of development...
- Regulation of Cdx2 expression by promoter methylation, and effects of Cdx2 transfection on morphology and gene expression of human esophageal epithelial cellsTong Liu
Susan Lehman Cullman Laboratory for Cancer Research, Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, 164 Frelinghuysen Road, Piscataway, NJ 08854, USA
Carcinogenesis 28:488-96. 2007Caudal-related homeobox 2 (Cdx2) has been suggested as an early marker of Barrett's esophagus (BE), which is the premalignant lesion of esophageal adenocarcinoma (EAC)...
- Defects in tracheoesophageal and lung morphogenesis in Nkx2.1(-/-) mouse embryosP Minoo
Department of Pediatrics, Women s and Children s Hospital, Los Angeles, California 90033, USA
Dev Biol 209:60-71. 1999..Failure in septation between the trachea and the esophagus in Nkx2...
- Altered expression of TFF-1 and CES-2 in Barrett's Esophagus and associated adenocarcinomasCharles A Fox
Digestive Health Center of Excellence, Division of Gastroenterology and Hepatology, University of Virginia, Charlottesville, VA 22908, USA
Neoplasia 7:407-16. 2005Identification of biomarkers to recognize individuals with Barrett's esophagus (BE) predisposed to develop malignancy is currently a pressing issue...
- Comparison of kinome profiles of Barrett's esophagus with normal squamous esophagus and normal gastric cardiaJantine W P M van Baal
Department of Cell Biology, University of Groningen, Groningen, The Netherlands
Cancer Res 66:11605-12. 2006The precursor metaplastic mucosal lesion that predisposes for esophageal adenocarcinoma is Barrett's esophagus. Because the signal transduction events that occur in Barrett's esophagus are poorly understood, this study aimed at ..
- Non-biopsy detection of intestinal metaplasia and dysplasia in Barrett's esophagus: a prospective multicenter studyP Sharma
University of Kansas School of Medicine and Veterans Affairs Medical Center, Kansas City, MO, USA
Endoscopy 38:1206-12. 2006..magnification chromoendoscopy (MCE) for the detection of intestinal metaplasia and dysplasia/cancer in Barrett's esophagus. Our aims were to assess the ability of MCE to predict the histological diagnosis (non-biopsy detection), to ..
- Eosinophils in the esophagus--peptic or allergic eosinophilic esophagitis? Case series of three patients with esophageal eosinophiliaPeter Ngo
Division of Pediatric Gastroenterology, Children s Hospital, Boston, Massachusetts 02115, USA
Am J Gastroenterol 101:1666-70. 2006Scattered eosinophils in the distal esophagus traditionally provide the hallmark for peptic esophagitis, but the upper limit of eosinophils and the longitudinal extent of peptic inflammation along the esophagus are unknown...
- The prognostic impact of O6-Methylguanine-DNA Methyltransferase (MGMT) promotor hypermethylation in esophageal adenocarcinomaS Baumann
Institute for Pathology and Pathologic Anatomy, Technical University of Munich, Munich, Germany
Int J Cancer 119:264-8. 2006..In conclusion, MGMT hypermethylation in esophageal adenocarcinoma is a frequent event that is associated with loss of MGMT protein expression but not with patient's outcome...
- A comparative analysis by SAGE of gene expression profiles of Barrett's esophagus, normal squamous esophagus, and gastric cardiaJantine W P M van Baal
Laboratory of Experimental Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
Gastroenterology 129:1274-81. 2005The metaplastic process in which the normal squamous epithelium of the distal esophagus is replaced by columnar-lined epithelium, known as Barrett's esophagus (BE), is poorly understood...
- Conversion of columnar to stratified squamous epithelium in the developing mouse oesophagusWei Yuan Yu
Department of Biology and Biochemistry, Centre for Regenerative Medicine, University of Bath, Claverton Down, Bath BA2 7AY, UK
Dev Biol 284:157-70. 2005..The results show that, in normal development, the squamous epithelium arises from the columnar epithelium by a direct conversion process...
- Incidence of adenocarcinoma among patients with Barrett's esophagusFrederik Hvid-Jensen
Department of Surgical Gastroenterology L, Aarhus University Hospital, Aarhus, Denmark
N Engl J Med 365:1375-83. 2011Accurate population-based data are needed on the incidence of esophageal adenocarcinoma and high-grade dysplasia among patients with Barrett's esophagus.
- Forkhead box M1 transcriptional factor is required for smooth muscle cells during embryonic development of blood vessels and esophagusVladimir Ustiyan
Divisions of Pulmonary Biology, Perinatal Institute of the Cincinnati Children s Hospital Research Foundation, 3333 Burnet Ave, Cincinnati, OH 45229, USA
Dev Biol 336:266-79. 2009..mice died immediately after birth due to severe pulmonary hemorrhage and structural defects in arterial wall and esophagus. Although Foxm1 deletion did not influence SMC differentiation, decreased proliferation of SMC was found in ..
- Safety and efficacy of endoscopic spray cryotherapy for Barrett's esophagus with high-grade dysplasiaNicholas J Shaheen
Center for Esophageal Diseases and Swallowing, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599 7080, USA
Gastrointest Endosc 71:680-5. 2010Endoscopic ablation to treat Barrett's esophagus (BE) with high-grade dysplasia (HGD) is associated with a decreased incidence of esophageal adenocarcinoma. Endoscopic spray cryotherapy (CRYO) demonstrates promising preliminary data.
- Definition of Barrett's esophagus: time for a rethink--is intestinal metaplasia dead?Robert H Riddell
Mount Sinai Hospital, Toronto, Ontario, Canada
Am J Gastroenterol 104:2588-94. 2009The definition of Barrett's esophagus (BE) varies worldwide, particularly with regard to the need to identify goblet cells in esophageal biopsies in order to diagnose this condition...
- Regulation of CDX2 expression in esophageal adenocarcinomaNadine Vaninetti
Department of Pathology, Dalhousie University, Halifax, NS, Canada
Mol Carcinog 48:965-74. 2009Reflux of acidic gastric contents and bile acids into the lower esophagus has been identified to have a central role in esophageal malignancy and is reported to upregulate caudal-related homologue 2 (CDX2), a regulatory gene involved in ..
- Clinical practice. Barrett's EsophagusStuart Jon Spechler
Dallas Department of Veterans Affairs Medical Center and The University of Texas Southwestern Medical Center at Dallas, Dallas 75216, USA
N Engl J Med 346:836-42. 2002
- P53 and Ki-67 overexpression in gastroesophageal reflux disease--Barrett's esophagus and adenocarcinoma sequenceM Binato
Federal University of Santa Maria, Santa Maria, Rio Grande do Sul, Brazil
Dis Esophagus 22:588-95. 2009..001 and P < 0.05). Our results indicate that overexpression of p53 and increased Ki-67 could be associated with the development and progression to ACE in patients with GERD...
- Aberrant epithelial-mesenchymal Hedgehog signaling characterizes Barrett's metaplasiaDavid H Wang
Graduate Training Program in Cellular and Molecular Medicine, Johns Hopkins University, Baltimore, Maryland, USA
Gastroenterology 138:1810-22. 2010The molecular mechanism underlying epithelial metaplasia in Barrett's esophagus remains unknown...
- Usefulness of magnifying endoscopy with narrow band imaging for the detection of specialized intestinal metaplasia in columnar-lined esophagus and Barrett's adenocarcinomaKen ichi Goda
Department of Endoscopy, The Jikei University School of Medicine, Tokyo, Japan
Gastrointest Endosc 65:36-46. 2007Barrett's esophagus with specialized intestinal metaplasia (SIM) from columnar-lined esophagus is difficult to distinguish with routine endoscopy.
- NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional networkShinya Ohashi
Gastroenterology Division, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Gastroenterology 139:2113-23. 2010..However, the functional roles of Notch in esophageal squamous epithelial biology are unknown...
- Endoscopic radiofrequency ablation for Barrett's esophagus: 5-year outcomes from a prospective multicenter trialD E Fleischer
Mayo Clinic, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA
Endoscopy 42:781-9. 2010The AIM-II Trial included patients with nondysplastic Barrett's esophagus (NDBE) treated with radiofrequency ablation (RFA). Complete eradication of NDBE (complete response-intestinal metaplasia [CR-IM]) was achieved in 98...
- Intensity-modulated radiotherapy for locally advanced non-small-cell lung cancer: a dose-escalation planning studyYolande Lievens
Department of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium
Int J Radiat Oncol Biol Phys 80:306-13. 2011..To evaluate the potential for dose escalation with intensity-modulated radiotherapy (IMRT) in positron emission tomography-based radiotherapy planning for locally advanced non-small-cell lung cancer (LA-NSCLC)...
- Characterization of squamous esophageal cells resistant to bile acids at acidic pH: implication for Barrett's esophagus pathogenesisAaron Goldman
Department of Cell Biology and Anatomy, Univ of Arizona, 1501 N Campbell Ave P O Box 245044, Tucson, AZ 85724, USA
Am J Physiol Gastrointest Liver Physiol 300:G292-302. 2011Barrett's esophagus (BE) is a premalignant condition, where normal squamous epithelium is replaced by intestinal epithelium. BE is associated with an increased risk of developing esophageal adenocarcinoma (EAC)...
- CT features of esophageal emergenciesCatherine A Young
Mallinckrodt Institute of Radiology, Washington University School of Medicine, Barnes Jewish Hospital, St Louis, MO 63110, USA
Radiographics 28:1541-53. 2008..An awareness of the CT findings associated with the spectrum of acute esophageal disease facilitates the accurate and prompt diagnosis of esophageal emergencies and thereby contributes to a more successful outcome...
- Prevalence and risk factors of Barrett's esophagus in patients undergoing endoscopy for upper gastrointestinal symptomsLi Shou Xiong
Department of Gastroenterology, The First Affiliated Hospital, Sun Yat Sen University, Guangzhou, Guangdong Province, China
J Dig Dis 11:83-7. 2010To investigate the prevalence of Barrett's esophagus (BE) and its risk factors in patients undergoing endoscopy for upper gastrointestinal symptoms in a Chinese tertiary referral medical center.
- Treatment of oesophageal ulcerations using endoscopic transplantation of tissue-engineered autologous oral mucosal epithelial cell sheets in a canine modelT Ohki
Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan
Gut 55:1704-10. 2006....
- Deterioration of muscle function in the human esophagus with ageHans Gregersen
Center of Excellence in Visceral Biomechanics and Pain, Aalborg Hospital, Aalborg, Denmark
Dig Dis Sci 53:3065-70. 2008..Esophageal motor function is traditionally studied by means of manometry and radiography. Distension of the esophagus with evaluation of active and passive mechanical parameters have become available during recent years...
- Analysis of component findings in 79 patients diagnosed with VACTERL associationBenjamin D Solomon
Medical Genetics Branch, National Human Genome Research Institute, Bethesda, MD 20892, USA
Am J Med Genet A 152:2236-44. 2010..These findings have implications for both our understanding of VACTERL association and for the approach to research involving this condition...
- Intracorporeal circular stapling esophagojejunostomy using the transorally inserted anvil (OrVil) after laparoscopic total gastrectomyOh Jeong
Department of Gastroenterologic Surgery, Chonnam National University Hwasun Hospital, 160, Ilsim Ri, Hwasun eup, Hwasun Gun, Jeollanam do, 519 809, Korea
Surg Endosc 23:2624-30. 2009..The authors report the newly developed reconstruction technique after LTG: intracorporeal circular stapling esophagojejunostomy using the transorally inserted anvil (OrVil; Covidien, Mansfield, MA, USA)...
- Aberrant expression of CDX2 in Barrett's epithelium and inflammatory esophageal mucosaAkashi Eda
Department of Internal Medicine, Jichi Medical School, Yakushiji, Kawachi, Tochigi 329-0438, Japan
J Gastroenterol 38:14-22. 2003..These findings imply that the expression of CDX2 may be an early event leading to the development of Barrett's esophagus.
- Neurocognitive processing of esophageal central sensitization in the insula and cingulate gyrusAdeyemi Lawal
Division of Gastroenterology and Hepatology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
Am J Physiol Gastrointest Liver Physiol 294:G787-94. 2008..the neurocognitive processing in the cingulate and insular cortices to mechanical stimulation of the proximal esophagus following infusion of acid or phosphate buffer solution (PBS) into the esophagus...
- Fluorescence, reflectance, and light-scattering spectroscopy for evaluating dysplasia in patients with Barrett's esophagusI Georgakoudi
G R Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts 09139, USA
Gastroenterology 120:1620-9. 2001..to assess the potential of 3 spectroscopic techniques (fluorescence, reflectance, and light-scattering spectroscopy) individually and in combination, for evaluating low- and high-grade dysplasia in patients with Barrett's esophagus (BE).
- Updated guidelines for the diagnosis and treatment of gastroesophageal reflux diseaseKenneth R DeVault
Department of Medicine, Mayo Clinic College of Medicine, Jacksonville, FL, USA
Am J Gastroenterol 100:190-200. 2005..GERD is defined as symptoms or mucosal damage produced by the abnormal reflux of gastric contents into the esophagus. These guidelines were developed under the auspices of the American College of Gastroenterology and its Practice ..
- Dysphagia in agingSami R Achem
Department of Medicine, Mayo Clinic College of Medicine, Jacksonville, FL 32224, USA
J Clin Gastroenterol 39:357-71. 2005....
- Updated guidelines 2008 for the diagnosis, surveillance and therapy of Barrett's esophagusKenneth K Wang
Gastroenterology, College of Medicine, Tucson, AZ 85724, USA
Am J Gastroenterol 103:788-97. 2008
- Bone marrow progenitor cells contribute to esophageal regeneration and metaplasia in a rat model of Barrett's esophagusG Sarosi
Dallas VA Medical Center, Dallas, Texas 75216, USA
Dis Esophagus 21:43-50. 2008Barrett's esophagus develops when refluxed gastric juice injures the esophageal squamous lining and the injury heals through a metaplastic process in which intestinal-type columnar cells replace squamous ones...
- Prevalence of Barrett's esophagus in the general population: an endoscopic studyJukka Ronkainen
Centre for Family Medicine, Karolinska Institutet, Stockholm, Sweden
Gastroenterology 129:1825-31. 2005Barrett's esophagus (BE) is associated with esophageal adenocarcinoma, the incidence of which has been increasing dramatically. The prevalence of BE in the general population is uncertain because upper endoscopy is required for diagnosis...
- DNA abnormalities as marker of risk for progression of Barrett's esophagus to adenocarcinoma: image cytometric DNA analysis in formalin-fixed tissuesMing Fang
Center for Swallowing and Motility Disorders, VA Boston Healthcare System, Boston, MA 02215, USA
Am J Gastroenterol 99:1887-94. 2004OBJECTIVES: To examine DNA content abnormalities in patients with Barrett's esophagus (BE) who progress to esophageal adenocarcinoma, using image cytometric DNA analysis (ICDA) of formalin-fixed tissues...
- The targeting of the cyclin D1 oncogene by an Epstein-Barr virus promoter in transgenic mice causes dysplasia in the tongue, esophagus and forestomachH Nakagawa
Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, USA
Oncogene 14:1185-90. 1997..This transgene is transcribed specifically in the tongue, esophagus and forestomach, all sharing a stratified squamous epithelium...
- Ethnic differences in the prevalence of endoscopic esophagitis and Barrett's esophagus: the long and short of it allShanmugarajah Rajendra
Department of Medicine, Perak College of Medicine, Ipoh, Malaysia
Dig Dis Sci 49:237-42. 2004..The prevalence of erosive esophagitis and Barrett's esophagus in a multiethnic Malaysian population was studied, as well as the relationship of various factors associated ..
- The essential role of fibroblasts in esophageal squamous cell carcinoma-induced angiogenesisKazuhiro Noma
The Wistar Institute, Philadelphia, Pennsylvania 19104, USA
Gastroenterology 134:1981-93. 2008..Esophageal squamous cell carcinoma (ESCC) is known to be a highly angiogenic tumor. Here, we investigated the role of the stromal fibroblasts in the ESCC-induced angiogenic response using a novel 3-dimensional model...
- Duodenal-content reflux esophagitis induces the development of glandular metaplasia and adenosquamous carcinoma in ratsM Pera
Service of Gastrointestinal Surgery, IMD, Hospital Clinic, IDIBAPS, University of Barcelona Medical School, Villarroel 170, 08036 Barcelona, Spain
Carcinogenesis 21:1587-91. 2000..are thought to arise in areas of columnar metaplasia adjacent to the anastomosis, similar to Barrett's esophagus in humans. In contrast, the histogenesis of adenosquamous carcinomas is unclear...
- Proton pump inhibitors are associated with reduced incidence of dysplasia in Barrett's esophagusHashem B El-Serag
Sections of Gastroenterology and Health Services Research, The Houston Center for Quality of Care and Utilization Studies, 2002 Holcombe Boulevard (152, Houston, TX 77030, USA
Am J Gastroenterol 99:1877-83. 2004BACKGROUND AND AIMS: Esophageal acid exposure is important in the pathogenesis of Barrett's esophagus (BE), and possibly in the progression of BE to dysplasia and carcinoma...
- Role of the multichannel intraluminal impedance technique in infants and childrenMichiel P van Wijk
Department of Paediatric Gastroenterology and Nutrition, Emma Children s Hospital Academic Medical Centre, Amsterdam, The Netherlands
J Pediatr Gastroenterol Nutr 48:2-12. 2009..In addition, this technique will improve our understanding of (patho)physiological mechanisms in pediatric GERD and other esophageal motility disorders...
- The homeodomain protein CDX2 is an early marker of Barrett's oesophagusL M G Moons
Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands
J Clin Pathol 57:1063-8. 2004..Therefore, pathways that induce Cdx2 transcription in squamous epithelial cells may be important in BO development...
- Sensory and biomechanical properties of the esophagus in non-erosive reflux diseaseHariprasad Reddy
Center for Biomechanics and Pain, Department of Gastroenterology, University Hospital Aalborg, Denmark
Scand J Gastroenterol 42:432-40. 2007To investigate possible differences between patients with non-erosive gastroesophageal reflux disease (NERD) and controls in a) sensitivity of the distal esophagus after mechanical and thermal stimuli and b) the referred pain areas.
- Cdx1 and c-Myc foster the initiation of transdifferentiation of the normal esophageal squamous epithelium toward Barrett's esophagusDouglas B Stairs
Division of Gastroenterology, Department of Medicine, Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA
PLoS ONE 3:e3534. 2008Barrett's esophagus is a premalignant condition whereby the normal stratified squamous esophageal epithelium undergoes a transdifferentiation program resulting in a simple columnar epithelium reminiscent of the small intestine...
- Roles of epidermal growth factor and Na+/H+ exchanger-1 in esophageal epithelial defense against acid-induced injuryYasuhiro Fujiwara
Department of Gastroenterology, Osaka City University Graduate School of Medicine, Japan
Am J Physiol Gastrointest Liver Physiol 290:G665-73. 2006..Deficiency in endogenous EGF is associated with increased severity of esophagitis. EGF and NHE-1 play crucial roles in esophageal epithelial defense against acid...
- Cathepsin B is the driving force of esophageal cell invasion in a fibroblast-dependent mannerClaudia D Andl
Departments of Surgery and Cancer Biology, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
Neoplasia 12:485-98. 2010..These results suggest that the interplay between the epithelial compartment and the surrounding microenvironment is crucial to invasion into the extracellular matrix...
- Surgical management of type III and IV laryngotracheoesophageal clefts: the three-layered approachKENNETH GELLER
Division of Otolaryngology Head and Neck Surgery, University of Southern California, Keck School of Medicine, Children s Hospital of Los Angeles, Los Angeles, CA 90027, United States
Int J Pediatr Otorhinolaryngol 74:652-7. 2010....
- Proximal and distal esophageal sensitivity is decreased in patients with Barrett's esophagusAnne L Krarup
Mech Sense, Department of Gastroenterology, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark
World J Gastroenterol 17:514-21. 2011To investigate sensations to multimodal pain stimulation in the metaplastic and normal parts of the esophagus in patients with Barrett's esophagus (BE).
- Large intra- and inter-individual variability of genes expression levels limits potential predictive value of molecular diagnosis of dysplasia in Barrett's esophagusEwa E Hennig
Department of Gastroenterology and Hepatology, Medical Center for Postgraduate Education at the Maria Sklodowska Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland
J Mol Med (Berl) 86:233-42. 2008Barrett's esophagus represents a well-defined precursor lesion of esophageal adenocarcinoma, although only a subset of patients with these lesions advances to invasive cancer...
- Steroids in second degree caustic burns of the esophagus: a systematic pooled analysis of fifty years of human data: 1956-2006Jessica A Fulton
New York University and Bellevue Hospital Center and Consultant, New York City Poison Control Center New York, New York USA
Clin Toxicol (Phila) 45:402-8. 2007..Two analyses, including data from 1956-1991 and 1991-2003, respectively, disagreed in their therapeutic recommendations. Our objective is to re-evaluate the usefulness of steroids in grade II burns...
- Relief of dysphagia after laparoscopic Heller myotomy improves long-term quality of lifeYassar Youssef
Department of Surgery, Vanderbilt University School of Medicine, D 5203 MCN, Nashville, Tennessee 37232, USA
J Gastrointest Surg 11:309-13. 2007..The aim of the study was to assess the impact of residual dysphagia on QoL after laparoscopic Heller myotomy for achalasia...
- Identification and characterization of multiple corticotropin-releasing factor type 2 receptor isoforms in the rat esophagusS Vincent Wu
Center for Ulcer Research and Education, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles 90073, USA, and Division of Gastroenterology, Taipei Veterans General Hospital, Taiwan
Endocrinology 148:1675-87. 2007The rat esophagus shares some cellular features with skin squamous epithelium and striated muscle that express high levels of corticotropin-releasing factor type 2 (CRF2) receptors or their cognate ligand urocortin (Ucn) 1, 2, and 3...
- Endoscopic in vivo evaluation of tissue atypia in the esophagus using a newly designed integrated endocytoscope: a pilot trialH Inoue
Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan
Endoscopy 38:891-5. 2006A newly designed magnifying endoscope featuring an endocytoscopy function provided by ultrahigh magnification was evaluated in a pilot study in patients with various types of benign and malignant pathology in the esophagus.
- [Spontaneous intramural dissection of the esophagus]J L Domínguez-Jiménez
Unidad Clinica de Aparato Digestivo, Hospital Universitario Reina Sofia, Cordoba, Espana
Gastroenterol Hepatol 29:294-6. 2006Spontaneous intramural dissection of the esophagus (SIDE) is an unusual clinical entity...
- Incomplete duplication of the esophagus: a case reportPiyawan Chiengkriwate
Pediatric Surgery Unit, Department of Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkla 90110, Thailand
J Med Assoc Thai 88:1123-7. 2005A case of incomplete duplication of the esophagus diagnosed in a 20-month-old girl with an esophageal perforation is presented. X-ray films of the chest showed pneumomediastinum and subcutaneous emphysema...
- ECRG1, a novel esophageal gene, cloned and identified from human esophagus and its inhibition effect on tumorsWang Yueying
Cancer Institute, Chinese Academy of Medical Sciences and Peking Union Medical College 100021, China
Carcinogenesis 29:157-60. 2008ECRG-1 (esophageal cancer-related gene 1) has been previously found to be down-regulated in human esophagus cancer. Transient expression of green fluorescent protein (GFP)-tagged ECRG1 showed plasma membrane localization...
- Foreign bodies in the esophagusDov Weissberg
Department of Thoracic Surgery, Tel Aviv University Sackler School of Medicine, Israel
Ann Thorac Surg 84:1854-7. 2007One third of foreign bodies retained in the gastrointestinal tract are present in the esophagus. Their management depends on the anatomic location, shape and size of the foreign body, and duration of impaction.
- Age and gender affect likely manometric diagnosis: Audit of a tertiary referral hospital clinical esophageal manometry serviceJane M Andrews
Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, Adelaide, Australia
J Gastroenterol Hepatol 24:125-8. 2009..The aim of the present study therefore was to determine whether age and/or gender affect manometric diagnosis in a clinical motility service...
- Remote magnetic control of a wireless capsule endoscope in the esophagus is safe and feasible: results of a randomized, clinical trial in healthy volunteersJutta Keller
Department of Internal Medicine, Israelitic Hospital, Academic Hospital, University of Hamburg, Germany
Gastrointest Endosc 72:941-6. 2010..Remote control of esophageal capsule endoscopes could enhance diagnostic accuracy...
- Spontaneous rupture of middle thoracic esophagus: thoracoscopic treatmentValentino Fiscon
Department of General Surgery, Azienda ULSS 15 Alta Padovana, Via Riva Dell Ospedale, 1, 35013, Cittadella, Padova, Italy
Surg Endosc 24:2900-2. 2010Spontaneous rupture of the esophagus (so-called Boerhaave's syndrome) is considered a medical emergency. It carries a significant mortality rate and requires prompt treatment...
- Gastroesophageal reflux leads to esophageal cancer in a surgical model with miceJing Hao
Department of Chemical Biology, Susan Lehman Cullman Laboratory for Cancer Research, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
BMC Gastroenterol 9:59. 2009Esophago-gastroduodenal anastomosis with rats mimics the development of human Barrett's esophagus and esophageal adenocarcinoma by introducing mixed reflux of gastric and duodenal contents into the esophagus...
- [A study on the light microscopic measurement of intercellular space of squamous epithelium in lower-esophagus to diagnose gastroesophageal reflux disease]Rong Li Cui
Department of Gastroenterology, Peking University Third Hospital, Beijing 100191, China
Zhonghua Nei Ke Za Zhi 48:208-12. 2009To evaluate the significance of dilated intercellular space (DIS) of squamous epithelium in lower-esophagus which was measured at light microscopy (LM) in the diagnosis of gastroesophageal reflux disease (GERD).
- Successful treatment of severe refractory anastomotic stricture in an infant after esophageal atresia repair by endoscopic balloon dilation combined with systemic administration of dexamethasoneTomoro Hishiki
Department of Pediatric Surgery, Chiba University Hospital, Chiba University Graduate School of Medicine, 1 8 1 Inohana, Chuo Ku, Chiba, 260 8677, Japan
Pediatr Surg Int 25:531-3. 2009..Balloon dilation in combination with systemic dexamethasone administration may be an effective treatment that could substitute invasive techniques including surgical manipulation for severe refractory strictures...
- Homeostatic role of transforming growth factor-beta in the oral cavity and esophagus of mice and its expression by mast cells in these tissuesAllison Vitsky
Genzyme Corporation, 1 The Mountain Rd, Framingham, MA 01701 9322, USA
Am J Pathol 174:2137-49. 2009..inflammation, as well as dental dysplasia and epithelial hyperplasia and inflammation of both the gingiva and esophagus. In an effort to determine the cause of this site-specific pathology, we examined TGF-beta expression in these ..
- Three-dimensional left atrial and esophagus reconstruction using cardiac C-arm computed tomography with image integration into fluoroscopic views for ablation of atrial fibrillation: accuracy of a novel modality in comparison with multislice computed tomoGeorg Nölker
Medizinische Klinik, Klinikum Coburg, Coburg, Germany
Heart Rhythm 5:1651-7. 2008..Additional delineation of the esophagus might avoid severe side effects...
- Total endoscopic resection of Barrett esophagusS Seewald
Center of Gastroenterology, Klinik Hirslanden, Zurich, Switzerland
Endoscopy 40:1016-20. 2008Barrett's esophagus with high grade intraepithelial neoplasia is associated with disease progression at rates of greater than 10% per year...
- Gender differences in pain and biomechanical responses after acid sensitization of the human esophagusHariprasad Reddy
Center for Biomechanics and Pain, University Hospital Aalborg, DK-9000, Aalborg, Denmark
Dig Dis Sci 50:2050-8. 2005Our aims were to investigate gender differences to multimodal stimulations of the esophagus after experimentally induced sensitization. Thirty healthy age-matched subjects, 13 males and 17 females, were included...
- Real-time imaging of human cortical activity evoked by painful esophageal stimulationAnthony R Hobson
Section of GI Science, Division of Medicine and Neurosciences Hope, University of Manchester, Hope Hospital, Salford, Lancashire, UK
Gastroenterology 128:610-9. 2005..The aim of this study was to determine the spatiotemporal correlates of exogenous neural activity evoked by painful esophageal stimulation...
- Accuracy of endoscopic optical coherence tomography in the detection of dysplasia in Barrett's esophagus: a prospective, double-blinded studyGerard Isenberg
Department of Medicine, Division of Gastroenterology, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH 44106-5066, USA
Gastrointest Endosc 62:825-31. 2005..study evaluated the accuracy of EOCT for the diagnosis and the exclusion of dysplasia in patients with Barrett's esophagus. METHODS: A 2.4-mm diameter EOCT probe was modified for use with a cap-fitted, two-channel endoscope...
- Motor and sensory function of the esophagus: revelations through ultrasound imagingRavinder K Mittal
Department of Medicine University of California, San Diego and San Diego VA Medical Center, San Diego, CA 92161, USA
J Clin Gastroenterol 39:S42-8. 2005..It has provided a number of important insights into the longitudinal muscle function of the esophagus. Based on the ultrasound images and intraluminal pressure recordings, it is clear that there is synchrony in the ..
- The fetal esophagus: anatomical and physiological ultrasonographic characterization using a high-resolution linear transducerG Malinger
Prenatal Diagnosis Unit, The Edith Wolfson Medical Center, Holon and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
Ultrasound Obstet Gynecol 24:500-5. 2004To study the sonographic anatomy and physiology of the human fetal esophagus during the mid-trimester of pregnancy using a high-resolution linear transducer.
- Intraganglionic laminar endings and their relationships with neuronal and glial structures of myenteric ganglia in the esophagus of rat and mouseM Raab
Department of Anatomy I, University of Erlangen Nuremberg, Lehrstuhl I, Krankenhausstrasse 9, 91054, Erlangen, Germany
Histochem Cell Biol 122:445-59. 2004..laminar endings (IGLEs) represent the only vagal mechanosensory terminals in the tunica muscularis of the esophagus and may be involved in local reflex control...
- SEL1L and squamous cell carcinoma of the esophagusPaola Granelli
Dipartimento di Scienze Chirurgiche e Trapianti, Ospedale Maggiore Policlinico Milano Istituto di Ricovero e Cura a Carattere Scientifico, Milan
Clin Cancer Res 10:5857-61. 2004..It is located on 14q24.3-31, a region known to be lost in invasive cancer of the esophagus. We aimed to assess whether SEL1L could become a useful biomarker for this cancer...
- Sensory and motor function of the esophagus: lessons from ultrasound imagingRavinder K Mittal
Department of Medicine, University of California, San Diego, CA 92161, USA
Gastroenterology 128:487-97. 2005..ultrasound imaging has provided a number of important insights regarding the longitudinal muscle function of the esophagus. On the basis of the ultrasound images and intraluminal pressure recordings, it seems that there is synchrony in ..
- Plasma and esophageal mucosal levels of vitamin C: role in the pathogenesis and neoplastic progression of Barrett's esophagusA Fountoulakis
Academic Unit of Surgery, Epidemiology and Health Services Research, School of Medicine, University of Leeds, UK
Dig Dis Sci 49:914-9. 2004..Blood samples and endoscopic biopsies (squamous, Barrett's, and gastric mucosa) were obtained from 48 Barrett's esophagus (BE) patients, while 48 age- and sex-matched controls provided blood samples only...
- [Barrett's esophagus]W K H Kauer
Chirurgische Klinik und Poliklinik, Klinikum rechts der Isar der Technischen Universitat Munchen
Chirurg 76:258-62. 2005It is widely accepted that long segments of Barrett's esophagus are caused by end-stage gastroesophageal reflux disease (GERD), but little is known about the correlation of severity of GERD and extent of metaplasia.
- Surgical repair of redundant intra-thoracic stomach after Ivor Lewis esophagectomyS E Shindel
Department of Surgery, Union Memorial Hospital, Baltimore, Maryland 21218, USA
Dis Esophagus 19:114-8. 2006..The diagnosis, technique of surgical revision, and outcome is discussed...
- [Barrett's esophagus]H Neuhaus
Medizinische Klinik, Evangelisches Krankenhaus Düsseldorf
Praxis (Bern 1994) 93:1951-7. 2004The diagnosis of Barrett's esophagus is rendered based on proof of intestinal metaplasia in the tubular portion of the esophagus...
- The effects of glucose on central vagal brainstem circuitsKIRSTEEN NAIRN BROWNING; Fiscal Year: 2010..The receptive relaxation reflex is a classical, vagally-mediated reflex activated upon distension of the esophagus (during swallowing, for example) that induces gastric relaxation and suppression of motility, allowing the ..
- THE HIGH PRESSURE ZONE OF THE DISTAL ESOPHAGUSLarry Miller; Fiscal Year: 2006..and contraction of the CD in relationship to the LES, the compressive effect and forces of the CD on the distal esophagus, the role of the CD in antegrade movement of liquids and the role of the CD in induced relaxation of the GEJHPZ ..
- Effect of Chronic Proton Pump Inhibitor Therapy on Bone Mineral Density and BoneYu Xiao Yang; Fiscal Year: 2009..take these potent acid suppressants on a long-term and continuous basis for erosive esophagitis, Barrett's esophagus and protection against nonsteroidal anti-inflammatory drug-related gastropathy...
- Effect of Chronic Proton Pump Inhibitor Therapy on Bone Mineral Density and BoneYu Xiao Yang; Fiscal Year: 2010..take these potent acid suppressants on a long-term and continuous basis for erosive esophagitis, Barrett's esophagus and protection against nonsteroidal anti-inflammatory drug-related gastropathy...
- Modeling Neoplastic Progression in Barrett's EsophagusJohn W Pepper; Fiscal Year: 2010..We propose to develop an agent-based computational model of neoplastic progression in Barrett's esophagus as a tool to study the dynamics of neoplastic progression and to integrate the genetic, pathological, clinical, ..
- Modeling Neoplastic Progression in Barrett's EsophagusCarlo Maley; Fiscal Year: 2009..We propose to develop an agent-based computational model of neoplastic progression in Barrett's esophagus as a tool to study the dynamics of neoplastic progression and to integrate the genetic, pathological, clinical, ..
- Determinants of AGR2 effects in Barrett's esophagus and esophageal adenocarcinomaAnson W Lowe; Fiscal Year: 2010Barrett's esophagus is a premalignant lesion that increases the risk for esophageal adenocarcinoma...
- The Prevalence of Barrett's Esophagus in Patients with *Blair Jobe; Fiscal Year: 2004..improvement in survival of patients with cancers detected by routine endoscopic surveillance for Barrett's esophagus. In spite of these efforts, the majority of patients who develop esophageal adenocarcinoma are unaware of the ..
- Photoacoustic endoscopy of Barretts esophagusQIFA NO ZHOU; Fiscal Year: 2010..Parts of the gastrointestinal tract, including the esophagus, large intestine, and rectum, and/or parts of the cardiovascular system of animals, will be imaged in vivo or ex ..
- Micro RNA expression in esophageal adenocarcinomaVirginia Litle; Fiscal Year: 2007..Chronic reflux exposes the distal esophagus to stomach acid and bile causing irritation and inflammation...
- H. PYLORI AND IL-1Beta IN ESOPHAGEAL ONCOGENESISFritz Francois; Fiscal Year: 2007..The gastric inflammatory response to H. pylori may decrease acid production and reflux in the esophagus. Differences in the host mucosal inflammatory response to H...
- NADPH oxidase-associated transition from Barrett's esophagus to adenocarcinomaWeibiao Cao; Fiscal Year: 2010..Approximately 10% of GERD patients develop Barrett's esophagus (BE), which is associated with nearly a 30-125-fold increased risk for the development of esophageal ..
- The role of KLF5 in GI epithelial homeostasis and diseaseJonathan Katz; Fiscal Year: 2009..vitro, is expressed in proliferating cells of gastrointestinal tract epithelia, including the basal cells of the esophagus. The interplay of these cells with the extracellular matrix (ECM) is critical to their function, and we have ..
- The role of KLF5 in GI epithelial homeostasis and diseaseJonathan Katz; Fiscal Year: 2009..vitro, is expressed in proliferating cells of gastrointestinal tract epithelia, including the basal cells of the esophagus. The interplay of these cells with the extracellular matrix (ECM) is critical to their function, and we have ..
- The temporal epigenomic program of Barrett's neoplastic progressionStephen J Meltzer; Fiscal Year: 2010Barrett's esophagus (BE), a sequela of chronic gastroesophageal reflux disease (GERD), is a premalignant condition that increases an individual's chance of developing esophageal adenocarcinoma (EAC) by 30-125- fold...
- The temporal epigenomic program of Barrett's neoplastic progressionStephen Meltzer; Fiscal Year: 2009Barrett's esophagus (BE), a sequela of chronic gastroesophageal reflux disease (GERD), is a premalignant condition that increases an individual's chance of developing esophageal adenocarcinoma (EAC) by 30-125- fold...
- Animal Model of Barrett's EsophagusXiaoxin Chen; Fiscal Year: 2003The aim of this project is to investigate the role of bile acids in the development of Barrett's esophagus (BE), and to develop an animal model for BE and esophageal adenocarcinoma (EAC)...
- BIOPHYSICAL PRINCIPLES OF PERISTALTIC PHENOMENAPiero Biancani; Fiscal Year: 1993..and if untreated may result in chronic esophagitis, aspiration pneumonia, esophageal strictures, and Barretts esophagus, a premalignant condition...
- NADPH oxidases-associated transition from Barrett's esophagus to adenocarcinomaWeibiao Cao; Fiscal Year: 2007..Approximately 10% of GERD patients develop Barrett's esophagus (BE) where esophageal squamous epithelium damaged by reflux esophagitis is replaced by a metaplastic, intestinal-..
- Improving Screening and Surveillance in Barrett's PatientsGuillermo J Tearney; Fiscal Year: 2010Barrett's esophagus (BE) is a metaplastic condition that is associated with chronic gastroesophageal reflux disease (GERD)...
- Combinational Chemoprevention of Esophageal Adenocarcin*Navtej Buttar; Fiscal Year: 2005Barrett's esophagus is a pre-malignant condition that predisposes to esophageal adenocarcinoma, which has one of the fastest rising incidence rates in the United States and has limited therapeutic options...
- A NOVEL TECHNIQUE FOR SCREENING BARRETT'S ESOSPHAGUSKenneth Wang; Fiscal Year: 2003..cancers are the most rapidly increasing cancer in Caucasian males and are a consequence of Barrett's esophagus. Barrett's esophagus is a pre-malignant condition that is produced by gastroesophageal reflux disease (heartburn)..
- INFLAMMATION AND SIGNAL TRANSDUCTION IN ESOPHAGITISPiero Biancani; Fiscal Year: 2010..the development of serious complications including ulcers, strictures, bleeding, columnar metaplasia (Barretts esophagus), and eventually adenocarcinoma of the esophagus...
- INFLAMMATION AND SIGNAL TRANSDUCTION IN ESOPHAGITISPiero Biancani; Fiscal Year: 2009..the development of serious complications including ulcers, strictures, bleeding, columnar metaplasia (Barretts esophagus), and eventually adenocarcinoma of the esophagus...
- Role of H. Pylori Infection in Esophageal AdenocarcinomaKam Meng Tchou Wong; Fiscal Year: 2003..Colonization with cagA+ strains has been shown to be inversely associated with reflux esophagitis and Barrett's esophagus. A lower prevalence of cagA+ Helicobacter pylori has been observed in patient with gastroesophageal reflux ..
- Biomarkers in Phototherapy of Barrett's EsophagusKenneth Wang; Fiscal Year: 2006The purpose of this study is to define the role of biomarkers in photodynamic therapy of Barrett's esophagus. Barrett's esophagus is felt to be the predisposing condition for the most rapidly increasing cancer in Caucasian males...
- Mechanistic Analysis of Eosinophilic EsophagitisAnil Mishra; Fiscal Year: 2009Eosinophilic esophagitis (EE) is an inflammatory disease of the esophagus that is being increasingly recognized especially during childhood. Notably, 70% of EE cases develop along with allergic asthma...
- Genetic Linkage Analysis of Barrett's EsophagusYvonne Romero; Fiscal Year: 2005..Barrett's esophagus, a premalignant lining of the esophagus, is the most robust risk factor for this highly lethal cancer...