ampulla of vater

Summary

Summary: A dilation of the duodenal papilla that is the opening of the juncture of the COMMON BILE DUCT and the MAIN PANCREATIC DUCT, also known as the hepatopancreatic ampulla.

Top Publications

  1. ncbi Endoscopic balloon dilation of the biliary sphincter compared to endoscopic biliary sphincterotomy for removal of common bile duct stones during ERCP: a metaanalysis of randomized, controlled trials
    Todd H Baron
    Department of Medicine, Division of Gastroenterology and Hepatology, Mayo Medical Center, Rochester, Minnesota, USA
    Am J Gastroenterol 99:1455-60. 2004
  2. ncbi Osteopontin-positive infiltrating tumor-associated macrophages in bulky ampullary cancer predict survival
    Hui Ping Hsu
    Department of Surgery, National Cheng Kung University Hospital, National Cheng Kung University, Tainan, Taiwan
    Cancer Biol Ther 10:144-54. 2010
  3. ncbi Association of ampullary and colorectal malignancies
    Ananya Das
    Division of Gastroenterology, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Cancer 100:524-30. 2004
  4. ncbi Mucins and CD56 as markers of tumour invasion and prognosis in periampullary cancer
    M M Aloysius
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre, National Institute for Health Research Biomedical Research Unit, Nottingham University Hospitals, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Br J Surg 97:1269-78. 2010
  5. ncbi Outcome of pancreaticoduodenectomy and impact of adjuvant therapy for ampullary carcinomas
    J H Lee
    Departments of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Int J Radiat Oncol Biol Phys 47:945-53. 2000
  6. ncbi Role of adjuvant chemoradiation therapy in adenocarcinomas of the ampulla of vater
    Sunil Krishnan
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Int J Radiat Oncol Biol Phys 70:735-43. 2008
  7. ncbi Risk factors for acute pancreatitis after endoscopic papillary balloon dilation
    Masanori Sugiyama
    First Department of Surgery, Kyorin University School of Medicine, 6 20 2 Shinkawa, Mitaka, Tokyo 181 8611, Japan
    Hepatogastroenterology 50:1796-8. 2003
  8. ncbi Cytokeratin 20 (CK20) and apomucin 1 (MUC1) expression in ampullary carcinoma: Correlation with tumor progression and prognosis
    Yasunari Kawabata
    Department of Digestive and General Surgery, Shimane University Faculty of Medicine, 89 1 Enyacho, Izumo, Shimane 693 8501, Japan
    Diagn Pathol 5:75. 2010
  9. ncbi Lymph node involvement and not the histophatologic subtype is correlated with outcome after resection of adenocarcinoma of the ampulla of vater
    Luciana Bertocco de Paiva Haddad
    Digestive Surgery Division, Department of Gastroenterology, University of Sao Paulo School of Medicine, R Aracaju 42, AP 41, Higienopolis, São Paulo 0501240030, Brazil
    J Gastrointest Surg 14:719-28. 2010
  10. ncbi Pathogenesis of carcinoma of the papilla of Vater
    Hans-Peter Fischer
    Department of Pathology, University of Bonn, Sigmund-Freud-Str. 25, D-53127, Bonn, Germany
    J Hepatobiliary Pancreat Surg 11:301-9. 2004

Detail Information

Publications228 found, 100 shown here

  1. ncbi Endoscopic balloon dilation of the biliary sphincter compared to endoscopic biliary sphincterotomy for removal of common bile duct stones during ERCP: a metaanalysis of randomized, controlled trials
    Todd H Baron
    Department of Medicine, Division of Gastroenterology and Hepatology, Mayo Medical Center, Rochester, Minnesota, USA
    Am J Gastroenterol 99:1455-60. 2004
    ..Although EPBD is theoretically attractive for use in young patients for biliary sphincter preservation, the rate of pancreatitis is higher with EPBD and cannot be routinely recommended at this time...
  2. ncbi Osteopontin-positive infiltrating tumor-associated macrophages in bulky ampullary cancer predict survival
    Hui Ping Hsu
    Department of Surgery, National Cheng Kung University Hospital, National Cheng Kung University, Tainan, Taiwan
    Cancer Biol Ther 10:144-54. 2010
    ..Osteopontin (OPN) is overexpressed in several human cancer cells and in TAMs. Therefore, we set out to determine the role of OPN-expressing macrophages in cancer...
  3. ncbi Association of ampullary and colorectal malignancies
    Ananya Das
    Division of Gastroenterology, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Cancer 100:524-30. 2004
    BACKGROUND: Because of the similarities in terms of carcinogenesis and natural history between cancer of the ampulla of Vater and colorectal cancer, the authors examined whether ampullary and colorectal malignancies occur in the same ..
  4. ncbi Mucins and CD56 as markers of tumour invasion and prognosis in periampullary cancer
    M M Aloysius
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre, National Institute for Health Research Biomedical Research Unit, Nottingham University Hospitals, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Br J Surg 97:1269-78. 2010
    ..This study investigated the association of mucins and cluster of differentiation (CD) 56 with vascular and perineural invasion and survival in patients with periampullary cancer...
  5. ncbi Outcome of pancreaticoduodenectomy and impact of adjuvant therapy for ampullary carcinomas
    J H Lee
    Departments of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Int J Radiat Oncol Biol Phys 47:945-53. 2000
    ..To determine the clinical outcomes and potential impact of adjuvant chemoradiation in patients undergoing surgical resection of ampullary carcinoma...
  6. ncbi Role of adjuvant chemoradiation therapy in adenocarcinomas of the ampulla of vater
    Sunil Krishnan
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Int J Radiat Oncol Biol Phys 70:735-43. 2008
    ..We retrospectively compared treatment outcomes in patients treated with pancreaticoduodenectomy alone versus those who received additional adjuvant CRT...
  7. ncbi Risk factors for acute pancreatitis after endoscopic papillary balloon dilation
    Masanori Sugiyama
    First Department of Surgery, Kyorin University School of Medicine, 6 20 2 Shinkawa, Mitaka, Tokyo 181 8611, Japan
    Hepatogastroenterology 50:1796-8. 2003
    ..Although EPBD (endoscopic papillary balloon dilation) may cause acute pancreatitis, risk factors for post-EPBD pancreatitis have not been well described. We retrospectively analyzed risk factors predictive of acute pancreatitis after EPBD...
  8. ncbi Cytokeratin 20 (CK20) and apomucin 1 (MUC1) expression in ampullary carcinoma: Correlation with tumor progression and prognosis
    Yasunari Kawabata
    Department of Digestive and General Surgery, Shimane University Faculty of Medicine, 89 1 Enyacho, Izumo, Shimane 693 8501, Japan
    Diagn Pathol 5:75. 2010
    ..We assessed the expression of cytokeratin (CK) and apomucin (MUC) in ampullary carcinoma (AC) to develop a system for the classification of ACs on the basis of their clinical significance...
  9. ncbi Lymph node involvement and not the histophatologic subtype is correlated with outcome after resection of adenocarcinoma of the ampulla of vater
    Luciana Bertocco de Paiva Haddad
    Digestive Surgery Division, Department of Gastroenterology, University of Sao Paulo School of Medicine, R Aracaju 42, AP 41, Higienopolis, São Paulo 0501240030, Brazil
    J Gastrointest Surg 14:719-28. 2010
    ..The aim of the present study was to determine the best immunohistochemical panel for tumor classification and to analyze the survival of patients having these histological types of adenocarcinoma...
  10. ncbi Pathogenesis of carcinoma of the papilla of Vater
    Hans-Peter Fischer
    Department of Pathology, University of Bonn, Sigmund-Freud-Str. 25, D-53127, Bonn, Germany
    J Hepatobiliary Pancreat Surg 11:301-9. 2004
    ..Consequently, the histologic classification should reflect the histogenesis of ampullary tumors from the two different types of papillary mucosa...
  11. ncbi ERCP in patients with long-limb Roux-en-Y gastrojejunostomy and intact papilla
    Byron E Wright
    Department of Surgery, Hennepin County Medical Center, Minneapolis, Minnesota 55415, USA
    Gastrointest Endosc 56:225-32. 2002
    ..Once the major papilla was accessed with a duodenoscope, advanced biliary and pancreatic therapeutic techniques were feasible...
  12. ncbi Carcinoid of the ampulla of Vater
    Mark Hartel
    Department of General Surgery, University of Heidelberg, Heidelberg, Germany
    J Gastroenterol Hepatol 20:676-81. 2005
    Endocrine neoplasms only rarely occur at the ampulla of Vater, comprising mostly carcinoids and malignant carcinoids, as well as few cases of poorly differentiated endocrine carcinomas (small cell carcinomas)...
  13. ncbi Carcinogenesis of cancer of the papilla and ampulla: pathophysiological facts and molecular biological mechanisms
    I Esposito
    Department of Visceral and Transplantation Surgery, University of Bern, Inselspital, Switzerland
    Langenbecks Arch Surg 386:163-71. 2001
    ....
  14. ncbi What is an appropriate indication for endoscopic papillary balloon dilation?
    Masaaki Natsui
    Department of Internal Medicine, Niigata Prefectural Shibata Hospital, Shibata, Japan
    Eur J Gastroenterol Hepatol 14:635-40. 2002
    ..In this study, we have evaluated the efficacy and safety of EPBD compared with endoscopic sphincterotomy (EST)...
  15. ncbi Muir-Torre syndrome: a case for surveillance of the ampulla of Vater
    J J Matthews
    Department of Surgery, Derriford Hospital, Plymouth, UK
    Dig Surg 19:65-6. 2002
    ..of multiple sebaceous tumours and kerato-acanthomas with internal malignancies, developed a carcinoma of the ampulla of Vater. This is the 2nd reported ampullary carcinoma in 205 reported cases of MTS, suggesting a higher prevalence in ..
  16. ncbi Carcinomas of the pancreas, gallbladder, extrahepatic bile ducts, and ampulla of vater share a field for carcinogenesis: a population-based study
    Donald Earl Henson
    George Washington University Cancer Institute, Washington, DC 20037, USA
    Arch Pathol Lab Med 133:67-71. 2009
    Carcinomas co-occur in the pancreas, extrahepatic bile ducts, and ampulla of Vater. We investigated whether cancers originating in these sites represent a field effect similar to that observed in the lung and upper aerodigestive tract.
  17. ncbi Pancreatoduodenectomy using a no-touch isolation technique
    Masahiko Hirota
    Department of Surgery, Kumamoto Regional Medical Center, 5 16 10 Honjo, Kumamoto City, Kumamoto 860 0811, Japan
    Am J Surg 199:e65-8. 2010
    ..In an effort to overcome these problems, we have developed a surgical technique for no-touch pancreatoduodenectomy...
  18. ncbi Expression of CD24, P-cadherin and S100A4 in tumors of the ampulla of Vater
    Daniel Baumhoer
    Institute of Pathology, University of Basel, Basel, Switzerland
    Mod Pathol 22:306-13. 2009
    ..therefore investigated their expression in 177 carcinoma, 114 adenoma and 152 normal mucosa specimens of the ampulla of Vater. Although the expression of the cell adhesion proteins did not differ between the carcinoma subtypes, marked ..
  19. ncbi Guidelines for the management of biliary tract and ampullary carcinomas: surgical treatment
    Satoshi Kondo
    Department of Surgical Oncology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    J Hepatobiliary Pancreat Surg 15:41-54. 2008
    ..The prognostic factors after resection for ampullary carcinoma include lymph node metastasis, pancreatic invasion, and perineural invasion...
  20. ncbi Frequency of colorectal polyps in patients with sporadic adenomas or adenocarcinomas of the papilla of vater--an age-matched, controlled study
    A R J Schneider
    Medical Department I, University Hospital, Frankfurt Main, Germany
    Z Gastroenterol 43:1123-7. 2005
    ..Patients with familial adenomatous polyposis bear a particularly increased risk for periampullary tumors. Data on whether the prevalence of colorectal tumors is increased in patients with sporadic ampullary neoplasms are scarce...
  21. ncbi Carcinoma of the ampulla of Vater associated with other organ malignancies
    N Eriguchi
    Department of Surgery, Sasebo Kyosai Hospital, 10-17 Shimanji-cho, Sasebo 857-8575, Japan
    Kurume Med J 48:255-9. 2001
    Because of its location with respect to the biliary system, carcinoma of the ampulla of Vater is considered to manifest earlier in its course of development than carcinoma of the pancreas...
  22. ncbi Carcinoid tumors of the duodenum and the ampulla of Vater: current diagnostic and therapeutic approach in a series of 8 patients. Case series
    George C Nikou
    Section of Gastrointestinal Neuroendocrinology, First Department of Propaedeutic Internal Medicine of Athens University Medical School, Laiko Hospital, Athens, Greece
    Int J Surg 9:248-53. 2011
    ..To describe the specific characteristics of duodenal/perivaterian carcinoids and to analyze the diagnostic/therapeutic approach...
  23. ncbi Duodenojejunal intussusception secondary to hamartomatous polyps of duodenum surrounding the ampulla of Vater
    C S Hwang
    Division of Pediatric Surgery, Departments of Surgery and Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China
    J Pediatr Surg 36:1073-5. 2001
    ..This is the third case report of children in literature, but this is the first case of a child with intussusception surrounding the ampulla of Vater and a successful excision performed without damaging the ampulla of Vater.
  24. ncbi Esophageal squamous cell carcinoma with metastasis to the ampulla
    Jayaprakash Sreenarasimhaiah
    Department of Gastroenterology, Pathology, University of Texas Southwestern Medical Center, Dallas, USA
    Gastrointest Endosc 62:310-1; discussion 311. 2005
  25. ncbi The inability to visualize the ampulla of Vater is an inherent limitation of capsule endoscopy
    Warwick S Selby
    AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia
    Eur J Gastroenterol Hepatol 23:101-3. 2011
    Lesions missed by capsule endoscopy (CE) have been reported and this may be partly because of the properties of the capsule. We aimed to compare the ability of Pillcam SB1, SB2, ESO1 and ESO2 to identify the ampulla of Vater (AoV).
  26. ncbi Predictors for patterns of failure after pancreaticoduodenectomy in ampullary cancer
    Hui Ping Hsu
    Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, 138, Sheng Li Road, Tainan, 70428, Taiwan, ROC
    Ann Surg Oncol 14:50-60. 2007
    ..The current study tried to find the predictors for recurrence to be used as determinative for postoperative adjuvant therapy...
  27. ncbi Differentiation pathways in duodenal and ampullary carcinomas: a comparative study on mucin and trefoil peptide expression, including gastric and colon carcinomas
    Yesim Gurbuz
    Department of Pathology, University of Kocaeli, Turkey
    Virchows Arch 444:536-41. 2004
    ..This also holds for ampullary carcinomas. Among the markers used, MUC5AC, MUC6 and TFF1 are most useful for revealing differentiation pathways in duodenal and ampullary carcinoma...
  28. ncbi High-grade neuroendocrine carcinoma of the ampulla of vater: a clinicopathologic and immunohistochemical analysis of 14 cases
    Hind Nassar
    Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
    Am J Surg Pathol 29:588-94. 2005
    ..the clinical and pathologic features of 14 cases of high-grade neuroendocrine carcinoma (HGNEC) of the ampulla of Vater classified according to WHO classification of lung tumors into small cell carcinoma (SCC, 6 cases) and large ..
  29. ncbi Recurrent disease after microscopically radical (R0) resection of periampullary adenocarcinoma in patients without adjuvant therapy
    Steve M M de Castro
    Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands
    J Gastrointest Surg 8:775-84; discussion 784. 2004
    ..Patients with ampulla of Vater and distal common bile duct adenocarcinoma indicate a much more favorable prognosis...
  30. ncbi Mucin 2 (MUC2) and mucin 5 (MUC5) expression is not associated with prognosis in patients with radically resected ampullary carcinoma
    D Santini
    , Via E Longoni no degrees 83, 00155 Rome, Italy
    J Clin Pathol 60:1069-70. 2007
  31. ncbi Improved survival for adenocarcinoma of the ampulla of Vater: fifty-five consecutive resections
    John P Duffy
    Section of Gastrointestinal Surgery, David Geffen School of Medicine, University of California-Los Angeles, 90095, USA
    Arch Surg 138:941-8; discussion 948-50. 2003
    HYPOTHESIS: After resection of an adenocarcinoma of the ampulla of Vater, certain clinical and pathologic characteristics influence long-term survival. DESIGN: Retrospective case series...
  32. ncbi Risk of subsequent primary cancers in patients with carcinoma of the Ampulla of Vater
    A Moran
    Centre for Cancer Epidemiology, University of Manchester, Christie Hospital NHS Trust, UK
    Br J Cancer 76:1232-3. 1997
    ..Four cancers were identified compared with 6.62 expected (relative risk 0.60), suggesting that individuals with ampullary carcinoma are not at increased risk of developing subsequent primary cancers...
  33. ncbi To cut or stretch?
    Henning Gerke
    Am J Gastroenterol 99:1461-3. 2004
    ..4% vs 4.3%). In addition, 20% of EPBD cases required "rescue" EST. EPBD should probably be reserved for special indications, such as uncorrected or anticipated coagulopathy, and unfavorable endoscopic anatomy for EST...
  34. ncbi Adjuvant therapy for ampullary carcinomas: the Mayo Clinic experience
    Sumita Bhatia
    Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 66:514-9. 2006
    PURPOSE: To determine the effects of adjuvant radiotherapy and chemotherapy for carcinoma of the ampulla of Vater. METHODS AND MATERIALS: We retrospectively reviewed the records of 125 patients who underwent definitive surgery for ..
  35. ncbi Maspin expression in adenocarcinoma of the ampulla of Vater: relation with clinicopathological parameters and apoptosis
    Stella Blandamura
    Section of Pathological Anatomy, Department of Medico Diagnostic Sciences and Special Therapies, University of Padova, Via Gabelli 61, 35121 Padova, Italy
    Anticancer Res 27:1059-65. 2007
    ..The aim of the present study was to investigate the role of maspin in ampullary adenocarcinomas, its correlation with apoptosis and its value as a prognostic marker...
  36. ncbi MK-1 expression in carcinoma of the ampulla of Vater as a predictor of improved prognosis after surgical resection
    Yoshihiro Hamada
    Department of Pathology, School of Medicine, Fukuoka University, 7 45 1 Nanakuma, Jonan ku, Fukuoka 814 0180, Japan
    Cancer Lett 243:211-6. 2006
    This retrospective study investigated the prognostic significance of MK-1 expression in human carcinoma of the ampulla of Vater (CAV)...
  37. ncbi Surgical management of neoplasms of the ampulla of Vater: local resection or pancreatoduodenectomy and prognostic factors for survival
    S M M de Castro
    Department of Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Surgery 136:994-1002. 2004
    BACKGROUND: Neoplasms of the ampulla of Vater have a better 5-year survival than pancreatic and bile duct neoplasms after resection...
  38. ncbi Hepatocyte nuclear factor (HNF) 4α expression distinguishes ampullary cancer subtypes and prognosis after resection
    Florian Ehehalt
    Department of General, Thoracic and Vascular Surgery, University Hospital Dresden, Germany
    Ann Surg 254:302-10. 2011
    ..To investigate biological differences and prognostic indicators of different ampullary cancer (AC) subtypes...
  39. ncbi Pancreaticoduodenectomy is curative in the majority of patients with node-negative ampullary cancer
    Kimberly M Brown
    Department of Surgery, Section of Surgical Oncology, Loyola University Medical Center, Maywood, IL 60153, USA
    Arch Surg 140:529-32; discussion 532-3. 2005
    ..CONCLUSION: Pancreaticoduodenectomy is curative in 80% of patients with node-negative ampullary carcinomas. Once 3-year survival is reached, long-term survival can be expected...
  40. ncbi Adjuvant chemoradiotherapy for "unfavorable" carcinoma of the ampulla of Vater: preliminary report
    V K Mehta
    Department of Radiation Oncology, Stanford University Medical Center, 300 Pasteur Dr, Stanford, CA 94305, USA
    Arch Surg 136:65-9. 2001
    ..Adjuvant chemoradiotherapy decreases the risk of local recurrence in patients with adenocarcinoma of the ampulla of Vater and high-risk features...
  41. ncbi Mutational profiling of kinases in human tumours of pancreatic origin identifies candidate cancer genes in ductal and ampulla of vater carcinomas
    Vincenzo Corbo
    ARC NET Research Center, University of Verona, Policlinico GB Rossi, Verona, Italy
    PLoS ONE 5:e12653. 2010
    ..Tumours of the pancreas are aggressive neoplasms for which no effective therapeutic strategy is currently available...
  42. ncbi Immunohistochemical study of mucin expression in periampullary adenomyoma
    Michiyo Higashi
    Department of Human Pathology, Field of Oncology, Kagoshima University Graduate School of Medical and Dental Sciences, 8 35 1 Sakuragaoka, Kagoshima, 890 8544, Japan
    J Hepatobiliary Pancreat Sci 17:275-83. 2010
    ....
  43. ncbi Ampullary cancer
    Stefan Heinrich
    Department of Visceral and Transplantation Surgery, Swiss HPB Center, University Hospital of Zurich, Zurich, Switzerland
    Curr Opin Gastroenterol 26:280-5. 2010
    ..This manuscript reviews the recent literature on ampullary cancer, including new staging definitions, histological characteristics and treatment options...
  44. ncbi Mixed acinar-endocrine carcinoma arising in the ampulla of Vater
    Joel T Moncur
    Department of Pathology, Walter Reed Army Medical Center, Washington, DC 20307, USA
    Hum Pathol 33:449-51. 2002
    ..The present article is the first reported case of an acinar cell carcinoma arising in the periampullary region of the duodenum, possibly in a focus of pancreatic heterotopia...
  45. ncbi Expression of MUC1 and MUC2 in ampullary cancer
    Toshiyuki Moriya
    Yamagata University, Yamagata, Japan
    Int J Surg Pathol 19:441-7. 2011
    ..Mucins are high-molecular-weight glycoproteins that play important roles in carcinogenesis or tumor invasion. The authors investigated the expression of mucins in ampullary cancer...
  46. ncbi Signet-ring-cell carcinoma of the ampulla of Vater: a case report
    Takashi Hara
    Department of Surgery, Kin-I-Kyo Chuou Hospital, 15-1, 10-jo, 2-chome, Fushiko, Higashi-ku, Sapporo, Hokkaido, 007-8505 Japan
    Hepatogastroenterology 49:561-3. 2002
    We encountered a rare variant of carcinoma of the ampulla of Vater in a 68-year-old man with postprandial abdominal pain and nausea. Ultrasonography and computed tomography showed a dilated common bile duct and main pancreatic duct...
  47. ncbi Neuroendocrine carcinoma of the ampulla of Vater: a clinicopathologic evaluation
    Eswaran Selvakumar
    Department of Surgical Gastroenterology, Government Stanley Medical College Hospital, Chennai 600001, Tamilnadu, India
    Hepatobiliary Pancreat Dis Int 7:422-5. 2008
    Only 105 cases of neuroendocrine tumor (NET) of the ampulla of Vater have been described, mostly as single case reports. The incidence of NET is rising. The changes in incidence may result from changes in detection...
  48. ncbi Clinicopathologic analysis of ampullary neoplasms in 450 patients: implications for surgical strategy and long-term prognosis
    Jordan M Winter
    Department of Surgery, Johns Hopkins Medical Institutions, Halsted 610, 600 N Wolfe Street, Baltimore, MD 21287, USA
    J Gastrointest Surg 14:379-87. 2010
    ..We sought to examine the outcome of patients undergoing pancreaticoduodenectomy versus ampullectomy, as well as to identify factors predictive of lymph node metastasis in patients with ampullary neoplasms...
  49. ncbi Adjuvant chemoradiation versus surgery alone for adenocarcinoma of the ampulla of Vater
    Jessica Zhou
    Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Hospital, 401 N Broadway, Baltimore, MD 21231, USA
    Radiother Oncol 92:244-8. 2009
    ..To examine the role of adjuvant chemoradiation (CRT) in patients with resected ampullary adenocarcinoma...
  50. ncbi Contribution of endoscopy to diagnosis and treatment of tumors of the ampulla of Vater
    T Ponchon
    , , Lyon, France
    Cancer 64:161-7. 1989
    In a series of 52 patients presenting with tumors of the ampulla of Vater, endoscopic procedures, especially endoscopic sphincterotomy and snare biopsies, permitted histologic classifications as follows: adenocarcinoma: 50%, adenoma: 35%, ..
  51. ncbi Non-pancreatic periampullary adenocarcinomas: an explanation for favorable prognosis
    Matthew H G Katz
    Department of Surgery, University of California San Diego, San Diego, California 92103, USA
    Hepatogastroenterology 51:842-6. 2004
    ..were resected in 120: pancreatic head (n=74), distal common bile duct (n=10), duodenum (n=5), and ampulla of Vater (n=31)...
  52. ncbi COX-2 expression of ampullary carcinoma: correlation with different histotypes and clinicopathological parameters
    Giuseppe Perrone
    Surgical Pathology, Campus Bio Medico University, Via Emilio Longoni, Rome, 83 00155, Italy
    Virchows Arch 449:334-40. 2006
    ..Furthermore, the high rate of COX-2 expression in the intestinal subtype of ampullary carcinoma may represent the rational for a histotype-tailored therapy targeting COX-2...
  53. ncbi Differential expression of metastasis-associated genes in papilla of vater and pancreatic cancer correlates with disease stage
    H Friess
    Department of Visceral and Transplantation Surgery and Institute of Pathology, University of Bern, Inselspital, Bern, Switzerland
    J Clin Oncol 19:2422-32. 2001
    ..Because metastasis formation is a critical step in tumor progression and a negative prognostic factor, we compared the expression of nm23-H1 and KAI1, two metastasis-suppressing genes, in papilla of Vater cancer and pancreatic cancer...
  54. ncbi Pancreaticoduodenectomy with or without pylorus preservation have similar outcomes
    Richard H Bell
    Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Cancer Treat Rev 31:328-31. 2005
  55. ncbi Therapeutic approach to tumors of the ampulla of Vater
    Akihiko Kobayashi
    Surgery Division, National Cancer Center Hospital East, Kashiwa City, Chiba, Japan
    Am J Surg 192:161-4. 2006
    BACKGROUND/AIM: Indications for local resection for tumors of the ampulla of Vater have not been established. The present study evaluated suitable treatments for tumors of the papilla of Vater...
  56. ncbi Phase II study of capecitabine and oxaliplatin for advanced adenocarcinoma of the small bowel and ampulla of Vater
    Michael J Overman
    Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Unit 426, Houston, TX 77030, USA
    J Clin Oncol 27:2598-603. 2009
    Adenocarcinomas of the small bowel and ampulla of Vater represent rare cancers that have limited data regarding first-line therapy...
  57. ncbi The clinical significance of papillitis of the major duodenal papilla
    Ju Sang Park
    Department of Internal Medicine and Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    Gastrointest Endosc 55:877-82. 2002
    ..Moderate and severe endoscopic papillitis are characteristic of biliary or pancreatic disorders...
  58. ncbi Expression of oncogene products HER2/Neu and Ras and fibrosis-related growth factors bFGF, TGF-beta, and PDGF in bile from biliary malignancies and inflammatory disorders
    W C Su
    Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan
    Dig Dis Sci 46:1387-92. 2001
    ..The results suggest overexpression of bFGF, PDGF, and HER2/Neu and the presence of K-ras mutation are important for carcinogenesis of bile duct cancers, and detection of the above abnormalities in bile is helpful for early diagnosis...
  59. ncbi Tumor of the ampulla of Vater: experience with local or radical resection in 171 consecutively treated patients
    H G Beger
    Department of General Surgery, University of Ulm, Germany
    Arch Surg 134:526-32. 1999
    ..We hypothesized that, in malignant lesions of the ampulla, the T and N stages are major determinants of the patient's long-term outcome...
  60. ncbi Still any role for transduodenal local excision in tumors of the papilla of Vater?
    Daniel Paramythiotis
    Department of General Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany
    J Hepatobiliary Pancreat Surg 11:239-44. 2004
    Tumors of the papilla and ampulla of Vater are rare neoplasms which are usually detected at an early stage due to their symptoms...
  61. ncbi Periampullary cancers: are there differences?
    J M Sarmiento
    Department of Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA
    Surg Clin North Am 81:543-55. 2001
    ....
  62. ncbi Neoplastic diseases of the papilla of Vater
    Wataru Kimura
    First Department of Surgery, Yamagata University School of Medicine, 2-2-2 Iida-Nishi, Yamagata 990-9585, Japan
    J Hepatobiliary Pancreat Surg 11:223-31. 2004
    ....
  63. ncbi Retroduodenal resection of ampullary carcinoid tumor in a patient with cavernous transformation of the portal vein
    Shin Hwang
    Division of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
    J Gastrointest Surg 11:1322-7. 2007
    ..This report describes a carcinoid tumor of the ampulla of Vater for which pancreatoduodenectomy was not feasible because of diffuse cavernous transformation of the portal ..
  64. ncbi An audit of outcomes of a series of periampullary carcinomas
    P O Berberat
    Department of General Surgery, University of Heidelberg, Heidelberg, Germany
    Eur J Surg Oncol 35:187-91. 2009
    ..This study describes the outcome and parameters, which predict survival of non-pancreatic periampullary carcinoma after resection...
  65. ncbi Human equilibrative nucleoside transporter 1 and carcinoma of the ampulla of Vater: expression differences in tumour histotypes
    G Perrone
    Department of Anatomical Pathology, Campus Bio Medico University, Via Alvaro del Portillo 200, Rome, Italy
    Eur J Histochem 54:e38. 2010
    ..by which gemcitabine enters human cells; recent evidence exists that hENT1 is expressed in carcinoma of the ampulla of Vater and that it should be considered as a molecular prognostic marker for patients with resected ampullary cancer...
  66. ncbi Tumors of the ampulla of Vater
    Michael Jean
    Medical College of Wisconsin, Froedtert Memorial Lutheran Hospital, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA
    Curr Gastroenterol Rep 5:171-5. 2003
    ..Stage of disease, patient characteristics (ie, age and comorbid conditions), and local availability of expertise determine treatment options...
  67. ncbi Patterns and predictors of failure after curative resections of carcinoma of the ampulla of Vater
    Takeshi Todoroki
    Departments of Surgery, Institute of Clinical Medicine, University of Tsukuba, Tsukuba shi, Japan
    Ann Surg Oncol 10:1176-83. 2003
    ..Curative resection does not always equate with long-term survival. The aim was to identify patterns and predictors of failure and independent factors of prognosis after curative resection...
  68. ncbi Endoscopic resection of an ampullary carcinoid presenting with upper gastrointestinal bleeding: a case report and review of the literature
    Nooman Gilani
    Department of Medicine and Research, Gastroenterology Section, Carl T Hayden Veterans Administration Medical Center, Phoenix, AZ 85012, USA
    World J Gastroenterol 13:1268-70. 2007
    ..We report a very rare case of a non-metastatic ampullary carcinoid causing upper gastrointestinal bleeding, which was managed by endoscopic ampullectomy...
  69. ncbi Status of surgical treatment of biliary tract cancer
    Shin Ishihara
    Department of Biliary Pancreatic Surgery, Fujita Health University, Toyoake, Japan
    Dig Surg 24:131-6. 2007
    ..The 5-year survival rate of pT1, pT2, pT3, and pT4 were 93.7, 65.1, 27.3, and 13.8%. PD or PPPD is the standard operation for carcinoma of the papilla of Vater. The 5-year survival rate was 57.5%...
  70. ncbi Tumors of the gallbladder, bile ducts, and ampulla
    Keith D Lillemoe
    Department of Surgery, Indiana University, School of Medicine, Indianapolis, IN 46202 5124, USA
    Semin Gastrointest Dis 14:208-21. 2003
    Neoplasms arising in the gallbladder, bile ducts, and ampulla of Vater pose a significant clinical challenge. Although benign neoplasms may be encountered, the majority of these tumors are malignant...
  71. ncbi Carcinoma of the papilla of Vater. Diagnostic and surgical problems
    Rossen Madjov
    Department of Surgery, Medical University, 55 M Drinov street, Varna 9002, Bulgaria
    Hepatogastroenterology 50:621-4. 2003
    ..Although carcinoma of the Vater's papilla is a well-recognized tumor, difficulties and misdiagnosis are still encountered in the early and on-time diagnostic process...
  72. ncbi Role of the DPC4 tumor suppressor gene in adenocarcinoma of the ampulla of Vater: analysis of 140 cases
    Denis M McCarthy
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Mod Pathol 16:272-8. 2003
    ..The contributions of these genetic alterations to the development of adenocarcinoma of the ampulla of Vater have not been fully established...
  73. ncbi Nodal involvement as an indicator of postoperative liver metastasis in carcinoma of the papilla of Vater
    Toshiyuki Moriya
    Gastroenterology and General Surgery, Yamagata University School of Medicine, Yamagata, Japan
    J Hepatobiliary Pancreat Surg 13:549-55. 2006
    ..To date, there has been reporting of extended lymph node dissection and adjuvant chemotherapy in patients with carcinoma of the papilla of Vater. Further studies will be necessary to resolve these problems...
  74. ncbi Prognostic significance of intratumoural microvessel density (IMD) in resected pancreatic and ampullary cancers to standard histopathological variables and survival
    A W Khan
    University Department of Surgery, Royal Free and University College Medical School, University College London, UK
    Eur J Surg Oncol 28:637-44. 2002
    ..003, HR 15.18). For ampullary cancers, IMD was higher in those with lymph node metastasis (P=0.02, Mann-Whitney U -test).CONCLUSION: IMD in resected pancreatic cancers correlates with survival...
  75. ncbi A prospective randomized trial of Tannenbaum-type Teflon-coated stents versus polyethylene stents for distal malignant biliary obstruction
    Anne Marie van Berkel
    Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands
    Eur J Gastroenterol Hepatol 16:213-7. 2004
    ..We compared the patency of a TTC stent with a conventional polyethylene (PE) stent in a prospective randomized trial...
  76. ncbi The need for a prophylactic gastrojejunostomy for unresectable periampullary cancer: a prospective randomized multicenter trial with special focus on assessment of quality of life
    N Tjarda Van Heek
    Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands
    Ann Surg 238:894-902; discussion 902-5. 2003
    ..Therefore, the trial was stopped earlier than planned...
  77. ncbi Purpose, use, and preparation of clinical practice guidelines for the management of biliary tract and ampullary carcinomas
    Tadahiro Takada
    Department of Surgery, Teikyo University School of Medicine, Tokyo, Japan
    J Hepatobiliary Pancreat Surg 15:2-6. 2008
    ..The grading of the recommendations is based on the determination of the level of evidence in references on which the recommendation is based...
  78. ncbi Successful pancreatoduodenectomy for carcinoma of the ampulla of vater after esophagectomy with remnant gastrectomy
    Yasuhiko Nagano
    Yokohama City University Medical Center, Gastroenterological Center, Yokohama City Graduate University School of Medicine, Yokohama, Japan
    Hepatogastroenterology 52:933-5. 2005
    ..Duodenoscopy was performed and showed the protruded lesion of the ampulla of Vater, biopsied specimens from this tumor revealed adenocarcinomas...
  79. ncbi Number of positive lymph nodes independently affects long-term survival after resection in patients with ampullary carcinoma
    J Sakata
    Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, 1 757 Asahimachi dori, Niigata City 951 8510, Japan
    Eur J Surg Oncol 33:346-51. 2007
    ..The nodal status is an established prognostic factor in ampullary carcinoma. The aim of this study was to compare the prognostic power of the anatomic location of positive nodes with that of the number of positive nodes...
  80. ncbi Clinicopathologic analysis of early ampullary cancers with a focus on the feasibility of ampullectomy
    Yoo-Seok Yoon
    Department of Surgery, Seoul National University College of Medicine, Seoul, Korea
    Ann Surg 242:92-100. 2005
    ..PD should be preferably performed for adequate radical resection, even in early ampullary cancer, and ampullectomy should be reserved for those who have pTis or pT1 cancer sized 1.0 cm or less with high operative risk...
  81. ncbi Human equilibrative nucleoside transporter 1 (hENT1) protein is associated with short survival in resected ampullary cancer
    D Santini
    Department of Medical Oncology, University Campus Bio Medico, via Emilio Longoni 81, 00155 Rome, Italy
    Ann Oncol 19:724-8. 2008
    ....
  82. ncbi Recurrence and prognostic factors of ampullary carcinoma after radical resection: comparison with distal extrahepatic cholangiocarcinoma
    Sang Myung Woo
    Department of Internal Medicine, Liver Research Institute, Seoul National University College of Medicine, 28 Yeongeon dong, Jongno gu, Seoul, Korea ROK
    Ann Surg Oncol 14:3195-201. 2007
    ..Ampullary carcinoma is often considered to have a better prognosis than distal extrahepatic cholangiocarcinoma. However, studies that directly compare the recurrence and histopathological features between the two groups are rare...
  83. ncbi Clinicopathologic features of ampullary carcinoma without jaundice
    Terumi Kamisawa
    Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital, Honkomagome, Tokyo, Japan
    J Clin Gastroenterol 40:162-6. 2006
    ..To evaluate clinicopathological features of ampullary carcinoma without jaundice...
  84. ncbi Guidelines for chemotherapy of biliary tract and ampullary carcinomas
    Junji Furuse
    Hepatobiliary and Pancreatic Oncology Division, National Cancer Center Hospital East, Kashiwa shi, Chiba, Japan
    J Hepatobiliary Pancreat Surg 15:55-62. 2008
    ..It is recommended that further clinical trials, especially large multi-institutional RCTs (phase III studies) using novel agents such as gemcitabine should be performed as soon as possible in order to establish a standard treatment...
  85. ncbi Standard whipple's operation versus pylorus preserving pancreaticoduodenectomy: a randomized controlled trial study
    Chatchai Srinarmwong
    Department of Surgery, Suratthani Hospital, Suratthani, Thailand
    J Med Assoc Thai 91:693-8. 2008
    ..A single-institution randomized controlled trial was conducted to compare the results of standard whipple operation (SW) with those of pylorus-preserving pancreaticoduodenectomy (PPPD)...
  86. ncbi The pylorus: take it or leave it? Systematic review and meta-analysis of pylorus-preserving versus standard whipple pancreaticoduodenectomy for pancreatic or periampullary cancer
    Paul J Karanicolas
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St W, Hamilton, Ontario, L85 3Z5, Canada
    Ann Surg Oncol 14:1825-34. 2007
    ..Our objective was to determine the relative effects of pylorus-preserving pancreaticoduodenectomy (PPPD) and standard Whipple pancreaticoduodenectomy (SWPD) in patients with pancreatic or periampullary cancer...
  87. ncbi Endoscopic resection of benign tumors of the papilla of vater
    S Bohnacker
    Department for Interdisciplinary Endoscopy, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Endoscopy 38:521-5. 2006
    ..The following article details the approach to patients with benign papillary tumor and the technique of endoscopic papillectomy...
  88. ncbi Mitomycin C with weekly 24-h infusion of high-dose 5-fluorouracil and leucovorin in patients with biliary tract and periampullar carcinomas
    J S Chen
    Division of Hematology Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital and Chang Gung University, Taipei, Taiwan, ROC
    Anticancer Drugs 12:339-43. 2001
    ..The median survival was 6 months. A combination of MMC with weekly high-dose 5-FU and LV in patients with BTC did not improve the response rate, but produced more toxicity than weekly high-dose 5-FU and LV alone...
  89. ncbi Periampullary gangliocytic paraganglioma
    P Sakhuja
    Department of Pathology, G.B.Pant Hospital, New Delhi, India
    J Clin Gastroenterol 33:154-6. 2001
    ..Because this lesion may present clinically as a periampullary carcinoma, it is important to recognize and diagnose this rare, but benign, entity...
  90. ncbi Expression of mucin carbohydrates and core proteins in carcinomas of the ampulla of Vater: their relationship to prognosis
    H Kitamura
    Second Department of Pathology, Faculty of Medicine, Kagoshima University, Kagoshima, Japan
    Jpn J Cancer Res 87:631-40. 1996
    ..as well as MUC2 gene product (intestinal-MRP antigen) in tissues from 38 patients with carcinoma of the ampulla of Vater, in order to determine whether these mucin antigens are available as tumor markers or not, and to evaluate ..
  91. ncbi Pathogenesis and treatment of neoplastic diseases of the papilla of Vater: Kausch-Whipple procedure with lymph node dissection in cancer of the papilla of Vater
    Hans G Beger
    Department of Surgery, Universiy of Ulm, Ulm, Germany
    J Hepatobiliary Pancreat Surg 11:232-8. 2004
    Cancer of the papilla or the ampulla of Vater appears, from a clinical point of view, to be an intraduodenal or ampullary cancer. An adenoma-dysplasia-carcinoma sequence has been established...
  92. ncbi Cancer of the papilla causing recurrent acute pancreatitis and mimicking a pancreatic stone
    Z-S Li
    Department of Gastroenterology, Digestive Endoscopy Center, Changhai Hospital, Second Military Medical University, Shanghai, China
    Endoscopy 39:E2. 2007
  93. ncbi Factors influencing recurrence after curative resection for ampulla of Vater carcinoma
    Joon Seong Park
    Department of Surgery, Yonsei University College of Medicine, Seoul, Korea
    J Surg Oncol 95:286-90. 2007
    Carcinoma of the ampulla of Vater has a relatively higher resection rate, lower recurrence rate, and more favorable prognosis than other malignant tumors of the periampullary region...
  94. ncbi Pancreaticoduodenectomy with extended retroperitoneal lymphadenectomy for periampullary adenocarcinoma
    Eugene P Kennedy
    Department of Surgery, Thomas Jefferson University, Jefferson Medical College, 1025 Walnut Street, Suite 605 College Building, Philadelphia, PA 19107, USA
    Surg Oncol Clin N Am 16:157-76. 2007
    ..These studies, including a large randomized trial of 280 patients from Johns Hopkins University, indicate that there is no demonstrable survival benefit to extended lymphadenectomy for periampullary cancer...
  95. ncbi Liver perfusion chemotherapy for selected patients at a high-risk of liver metastasis after resection of duodenal and ampullary cancers
    Takehiro Noda
    Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan
    Ann Surg 246:799-805. 2007
    ..To evaluate the prognostic benefit of postoperative liver perfusion chemotherapy (LPC) in patients who undergo curative resection of duodenal and ampullary cancers...
  96. ncbi Preoperative biliary drainage for periampullary tumors causing obstructive jaundice; DRainage vs. (direct) OPeration (DROP-trial)
    Niels A van der Gaag
    Department of Surgery, Academic Medical Center Amsterdam, The Netherlands
    BMC Surg 7:3. 2007
    ....
  97. ncbi Development of an integrated biospecimen bank and multidisciplinary clinical database for pancreatic cancer
    Rosa F Hwang
    Department of Surgical Oncology, Unit 444, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Ann Surg Oncol 15:1356-66. 2008
    ..We describe the development of an integrated pancreatic tissue bank (PTB) and clinical database for patients with pancreatic cancer and other pancreatic disorders...
  98. ncbi [Clinical significance of solitary lymph node metastasis in carcinoma of the ampulla of Vater]
    Yi Shan
    Department of Abdominal Surgical Oncology, Cancer Hospital (Institute, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China
    Zhonghua Zhong Liu Za Zhi 28:694-6. 2006
    ..of solitary lymph node metastasis and its relation with clinico-pathologic factors in carcinoma of ampulla of Vater. METHODS: The data of 26 patients who were discovered to have solitary lymph node metastasis, from 152 ..
  99. ncbi The surgical procedure and clinical results of subtotal stomach preserving pancreaticoduodenectomy (SSPPD) in comparison with pylorus preserving pancreaticoduodenectomy (PPPD)
    Akira Hayashibe
    Department of Surgery, Bell Land General Hospital, 500 8 Higashiyama, Sakai City, Osaka 599 8247, Japan
    J Surg Oncol 95:106-9. 2007
    ..Subtotal stomach preserving pancreaticoduodenectomy (SSPPD) is compared retrospectively with pylorus preserving pancreaticoduodenectomy (PPPD)...
  100. ncbi [Results of defunctionalized jejunal loop after pancreaticoduodenectomy]
    José M Jover
    Servicio de Cirugía General y Digestivo Hospital Universitario de Getafe Getafe Madrid España
    Cir Esp 80:373-7. 2006
    ..Anastomotic leak continues to be a common cause of complications after pancreaticoduodenectomy. Numerous surgical techniques have been described to avoid this complication...
  101. ncbi [Ampullectomy in benign lesion: indications and results]
    S Miossec
    , 184, rue du Faubourg-Saint-Antoine, 75012 Paris, France
    Ann Chir 129:73-8. 2004
    ..All other patients remain asymptomatic. CONCLUSION: Ampullectomy with accurate intra-operative frozen section appears adequate for presumed benign lesion of the papilla and ampulla...

Research Grants27

  1. INJURY TO LIVER SINUSOIDAL ENDOTHELIAL CELLS
    Steven Strasberg; Fiscal Year: 2003
    ..A potentially beneficial improvements in preservation solutions are identified they will be tested in whole isolated livers and by transplantation in the rat. ..
  2. COLLABORATIVE STUDY OF OVARIAN CANCER IN TWO RISK GROUPS
    MARC GOODMAN; Fiscal Year: 2005
    ..Dr. Anna Wu, the P.I. on the Los Angeles sub-contract during the first cycle of this grant, will assist with statistical analysis and the interpretation of results. ..
  3. DIET AND DURATION OF CERVICAL HPV INFECTION
    MARC GOODMAN; Fiscal Year: 2005
    ....
  4. DIET AND DURATION OF CERVICAL HPV INFECTION
    MARC GOODMAN; Fiscal Year: 2007
    ....
  5. Biomarkers of COX-2 inhibitors in intraductal papillary mucinous neoplasm (IPMN)
    Christian Schmidt; Fiscal Year: 2007
    ....
  6. DIET AND DURATION OF CERVICAL HPV INFECTION
    MARC GOODMAN; Fiscal Year: 2009
    ....
  7. DIET AND DURATION OF CERVICAL HPV INFECTION
    MARC GOODMAN; Fiscal Year: 2002
    ..Such knowledge may also assist in the development of appropriate screening strategies involving HPV DNA detection that could be targeted at women who would benefit most from intensive follow-up. ..
  8. COLLABORATIVE STUDY OF OVARIAN CANCER IN TWO RISK GROUPS
    MARC GOODMAN; Fiscal Year: 1993
    ....
  9. Collaborative Genetic Study of Ovarian Cancer Risk
    Marc T Goodman; Fiscal Year: 2010
    ..The identification of ovarian cancer susceptibility genes that are related to OSE wounding and post-ovulatory tissue remodeling might shed light on important vitamin D-associated pathways in the carcinogenic process. ..