sigmoid colon

Summary

Summary: A segment of the COLON between the RECTUM and the descending colon.

Top Publications

  1. ncbi Surgical treatment of Chagasic megacolon by abdominal rectosigmoidectomy with immediate posterior end-to-side stapling (Habr-Gama technique)
    Sergio C Nahas
    Department of Gastroenterology, Colorectal Surgery Division, University of Sao Paulo, School of Medicine, Rua Jabebira 136, 05602 020 São Paulo, SP, Brazil
    Dis Colon Rectum 49:1371-8. 2006
  2. ncbi Giant submucosal sigmoid colon lipoma
    Anil M Bahadursingh
    Department of Surgery, Division of Colon and Rectal Surgery, Saint Louis University Health Sciences Center, 3635 Vista at Grand, P.O. Box 15250, St. Louis, MO 63110-0250, USA
    Am J Surg 186:81-2. 2003
  3. ncbi Frequency of right lower quadrant position of the sigmoid colon in infants and young children
    D J Fiorella
    Department of Radiology, Duke University Medical Center, Durham, NC, USA
    Radiology 219:91-4. 2001
  4. ncbi Mesh penetration of the sigmoid colon following a transabdominal preperitoneal hernia repair
    B Lange
    Department of Surgery, , Robert-Koch-Strasse 40, , Germany
    Surg Endosc 17:157. 2003
  5. ncbi Late radiotherapy-induced lower intestinal toxicity (RILIT) of intensity-modulated radiotherapy for prostate cancer: the need for adapting toxicity scales and the appearance of the sigmoid colon as co-responsible organ for lower intestinal toxicity
    Valerie Fonteyne
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Radiother Oncol 84:156-63. 2007
  6. ncbi Comparison of outcome of POSSUM, p-POSSUM, and cr-POSSUM scoring after elective resection of the sigmoid colon for carcinoma or complicated diverticular disease
    Joannes L T Oomen
    Department of Surgery, Zaans Medical Centre, Zaandam, The Netherlands
    Scand J Gastroenterol 42:841-7. 2007
  7. ncbi Immune reconstitution in the sigmoid colon after long-term HIV therapy
    P M Sheth
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    Mucosal Immunol 1:382-8. 2008
  8. ncbi Endometriosis causing extensive intestinal obstruction simulating carcinoma of the sigmoid colon: a case report and review of the literature
    M Varras
    Department of Gynaecology, George Gennimatas General State Hospital of Athens, Greece
    Eur J Gynaecol Oncol 23:353-7. 2002
  9. ncbi Reversal of Hartmann's procedure after surgery for complications of diverticular disease of the sigmoid colon is safe and possible in most patients
    J L T Oomen
    Department of Surgery, Zaans Medical Centre, Zaandam, The Netherlands
    Dig Surg 22:419-25. 2005
  10. ncbi Management of patients with stercoral perforation of the sigmoid colon: report of five cases
    Wen Shih Huang
    Division of Colon and Rectal Surgery, Chang Gung Memorial Hospital, Pu tzu 613 Taiwan, China
    World J Gastroenterol 12:500-3. 2006

Research Grants

  1. NEUROENDOCRINE ALTERATIONS IN FIBROMYALGIA AND IBS
    Lin Chang; Fiscal Year: 2007
  2. Colon Barrier Breakdown in the Elderly
    James Mullin; Fiscal Year: 2005
  3. Calcium/Vitamin D, Biomarkers & Colon Polyp Prevention
    Roberd Bostick; Fiscal Year: 2007
  4. GENETIC ANALYSIS OF HIRSCHSPRUNG DISEASE
    Aravinda Chakravarti; Fiscal Year: 2001
  5. GENETIC ANALYSIS OF HIRSCHSPRUNG DISEASE
    Aravinda Chakravarti; Fiscal Year: 2007
  6. Aspirin, UGT1A6 Genotype, and Colon Gene Expression
    Johanna Lampe; Fiscal Year: 2006
  7. Relex Pathways Controlling Intestinal Motility
    TERENCE KEITH SMITH; Fiscal Year: 2010
  8. Relex Pathways Controlling Intestinal Motility
    Terence Smith; Fiscal Year: 2009
  9. Relex Pathways Controlling Intestinal Motility
    Terence Smith; Fiscal Year: 2009
  10. Aging and Cancer of the Colon
    STEVEN DUDAS; Fiscal Year: 2004

Detail Information

Publications240 found, 100 shown here

  1. ncbi Surgical treatment of Chagasic megacolon by abdominal rectosigmoidectomy with immediate posterior end-to-side stapling (Habr-Gama technique)
    Sergio C Nahas
    Department of Gastroenterology, Colorectal Surgery Division, University of Sao Paulo, School of Medicine, Rua Jabebira 136, 05602 020 São Paulo, SP, Brazil
    Dis Colon Rectum 49:1371-8. 2006
    ..The purpose of this study was to assess the technique and results of anterior rectosigmoidectomy with immediate posterior colorectal end-to-side stapled anastomosis for the treatment of Chagasic megacolon...
  2. ncbi Giant submucosal sigmoid colon lipoma
    Anil M Bahadursingh
    Department of Surgery, Division of Colon and Rectal Surgery, Saint Louis University Health Sciences Center, 3635 Vista at Grand, P.O. Box 15250, St. Louis, MO 63110-0250, USA
    Am J Surg 186:81-2. 2003
  3. ncbi Frequency of right lower quadrant position of the sigmoid colon in infants and young children
    D J Fiorella
    Department of Radiology, Duke University Medical Center, Durham, NC, USA
    Radiology 219:91-4. 2001
    P:URPOSE: To evaluate the frequency of right lower quadrant positioning of the sigmoid colon in infants and young children. MATERIALS AND METHODS: Findings in 169 patients who underwent enema examination were retrospectively reviewed...
  4. ncbi Mesh penetration of the sigmoid colon following a transabdominal preperitoneal hernia repair
    B Lange
    Department of Surgery, , Robert-Koch-Strasse 40, , Germany
    Surg Endosc 17:157. 2003
    ..pain and anal bleeding following a TAPP procedure may result from the penetration of the repair mesh into the sigmoid colon. In this case report, we discuss this particular complication following the TAPP procedure...
  5. ncbi Late radiotherapy-induced lower intestinal toxicity (RILIT) of intensity-modulated radiotherapy for prostate cancer: the need for adapting toxicity scales and the appearance of the sigmoid colon as co-responsible organ for lower intestinal toxicity
    Valerie Fonteyne
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Radiother Oncol 84:156-63. 2007
    ..Late radiotherapy-induced lower intestinal toxicity (RILIT) after intensity-modulated radiotherapy (IMRT) for prostate cancer. 2. The correlation between late RILIT and volume parameters of the rectum, sigmoid colon and small bowel.
  6. ncbi Comparison of outcome of POSSUM, p-POSSUM, and cr-POSSUM scoring after elective resection of the sigmoid colon for carcinoma or complicated diverticular disease
    Joannes L T Oomen
    Department of Surgery, Zaans Medical Centre, Zaandam, The Netherlands
    Scand J Gastroenterol 42:841-7. 2007
    ..To compare POSSUM, p-POSSUM, and cr-POSSUM-predicted mortalities with the observed postoperative mortality in patients undergoing elective sigmoid colectomy for diverticular disease (n=121) or carcinoma (n=120)...
  7. ncbi Immune reconstitution in the sigmoid colon after long-term HIV therapy
    P M Sheth
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    Mucosal Immunol 1:382-8. 2008
    ..Blood and sigmoid colon biopsies were collected from HAART-treated individuals with undetectable blood HIV RNA for > or =4 years and ..
  8. ncbi Endometriosis causing extensive intestinal obstruction simulating carcinoma of the sigmoid colon: a case report and review of the literature
    M Varras
    Department of Gynaecology, George Gennimatas General State Hospital of Athens, Greece
    Eur J Gynaecol Oncol 23:353-7. 2002
    ..Reported here is a case of extensive bowel obstruction due to sigmoid colon endometriosis in a 43-year-old woman who presented with signs and symptoms of bowel obstruction...
  9. ncbi Reversal of Hartmann's procedure after surgery for complications of diverticular disease of the sigmoid colon is safe and possible in most patients
    J L T Oomen
    Department of Surgery, Zaans Medical Centre, Zaandam, The Netherlands
    Dig Surg 22:419-25. 2005
    Although evidence is growing that most patients who need an operation for diverticular disease of the sigmoid colon can be treated by a single-stage procedure, a two-stage procedure will still be necessary in some patients because of ..
  10. ncbi Management of patients with stercoral perforation of the sigmoid colon: report of five cases
    Wen Shih Huang
    Division of Colon and Rectal Surgery, Chang Gung Memorial Hospital, Pu tzu 613 Taiwan, China
    World J Gastroenterol 12:500-3. 2006
    ..two males and three females, whose median age was 64 years, had sustained stercoral perforation of the sigmoid colon. Chronic constipation was the common symptom among these patients...
  11. ncbi Distribution of serotonin receptors and interacting proteins in the human sigmoid colon
    N Chetty
    Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia
    Neurogastroenterol Motil 21:551-8, e14-5. 2009
    ..Human sigmoid colon samples were dissected into three separate layers (mucosa, taeniae coli and intertaenial strips) and RNA was ..
  12. ncbi Exaggerated motility of the descending colon with repetitive distention of the sigmoid colon in patients with irritable bowel syndrome
    Shin Fukudo
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, 2-1 Seiryo, Aoba, Sendai 980-8575, Japan
    J Gastroenterol 37:145-50. 2002
    ..catheter with three transducers was inserted to the descending colon and a balloon was placed in the distal sigmoid colon. Another catheter with three transducers was inserted to the duodenum...
  13. ncbi Effect of bladder distension on dose distribution of intracavitary brachytherapy for cervical cancer: three-dimensional computed tomography plan evaluation
    Mustafa Cengiz
    Department of Radiation Oncology, Hacettepe University Faculty of Medicine, Sihhiye, Ankara, Turkey
    Int J Radiat Oncol Biol Phys 70:464-8. 2008
    ..To quantify the effect of bladder volume on the dose distribution during intracavitary brachytherapy for cervical cancer...
  14. ncbi Anatomy of the sigmoid colon, rectum, and the rectovaginal pouch in women with enterocele and anterior rectal wall procidentia
    Kaven Baessler
    Department of Obstetrics and Gynecology, Cantonal Hospital Lucerne, 6000 Lucerne 16, Switzerland
    Clin Anat 19:125-9. 2006
    This study describes the anatomy of the rectovaginal pouch, the sigmoid colon, and rectum in women with posterior enterocele and anterior rectal wall procidentia...
  15. ncbi Laparoscopically assisted sigmoid colon vaginoplasty in women with Mayer-Rokitansky-Kuster-Hauser syndrome: feasibility and short-term results
    B Cai
    Department of Obstetrics and Gynecology, Shanghai Jiao Tong University Affiliated First People s Hospital, Shanghai, PR China
    BJOG 114:1486-92. 2007
    To evaluate the technical feasibility and anatomical and functional outcomes of laparoscopically assisted sigmoid colon vaginoplasty (LASV) in women with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome.
  16. ncbi Toothpick impaction with sigmoid colon pseudodiverticulum formation successfully treated with colonoscopy
    Youn Son Chung
    Department of Gastroenterology, Hallym University College of Medicine, Anyang, Korea
    World J Gastroenterol 14:948-50. 2008
    ..We report our experience with a patient with a sigmoid colon pseudodiverticulum formation, a complication of accidental ingestion of a toothpick that was diagnosed and ..
  17. ncbi Vaginal construction using sigmoid colon in children and young adults
    Ashok Rajimwale
    The Children's Hospital, Denver, CO 80218, USA
    BJU Int 94:115-9. 2004
    ..RESULTS: A neovagina was constructed in 23 patients during the study period; sigmoid colon was used in 20 but not in two patients with cloacal exstrophy and in one with Mayer-Rokitansky-Kuster-Hauser ..
  18. ncbi Decreased interstitial cells of Cajal in the sigmoid colon of patients with slow transit constipation
    Wei Dong Tong
    Department of General Surgery, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, China
    Int J Colorectal Dis 19:467-73. 2004
    ..This study aimed to determine the normal distribution of ICC within the colon of the Chinese and also to determine if ICC are decreased in Chinese STC patients...
  19. ncbi Incidental finding of an intrauterine device in the sigmoid colon
    Loïc Sentilhes
    Department of Obstetrics and Gynaecology, Angers University Hospital, Angers, France
    Eur J Contracept Reprod Health Care 13:212-4. 2008
    Translocation of an intrauterine device (IUD) to the sigmoid colon lumen is an extremely rare presentation of an ectopic IUD that usually results in fever and gastrointestinal symptoms...
  20. ncbi Endometrioid adenocarcinoma arising from endometriosis of the mesenterium of the sigmoid colon
    Susumu Kawate
    Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine, 3 39 22 Showamachi, Maebashi, Gunma 371 8511, Japan
    Jpn J Clin Oncol 35:154-7. 2005
    This report presents a case of endometrioid adenocarcinoma arising from endometriosis of the mesenterium of the sigmoid colon following total abdominal hysterectomy and bilateral salpingo-oophorectomy for leiomyoma of the uterus and ..
  21. ncbi Laparoscopic vaginal reconstruction using a sigmoid colon segment: a preliminary report
    W Urbanowicz
    Department of Pediatric Urology, Polish-American Children's Hospital, Collegium Medicum, Jagiellonian University, Cracow, Poland
    J Urol 171:2632-5. 2004
    ..Average postoperative stay was 7 to 9 days. CONCLUSIONS: This preliminary report suggests that laparoscopic sigmoid vaginal replacement is feasible and safe, and may be used as an alternative to open surgery...
  22. ncbi Intestinal vaginoplasty: is it optimal treatment of vaginal agenesis? A pilot study. Surgical method of sigmoid colon vaginoplasty in vaginal agenesis
    Ates Karateke
    Department of Gynecology, Zeynep Kamil Women s and Children Diseases Education and Research Hospital, Uskudar, Istanbul, Turkey
    Int Urogynecol J Pelvic Floor Dysfunct 17:40-5. 2006
    ..Patients were between 18 and 37 years old. Ileum vaginoplasty and sigmoid colon vaginoplasty were carried out in two and nine cases, respectively...
  23. ncbi Sigmoid colon perforation following a migrated biliary stent
    Michael Elliott
    Hornsby Ku-ring-gai Hospital, Sydney, New South Wales, Australia
    ANZ J Surg 73:669-70. 2003
  24. ncbi Endoscopic biopsies in Ussing chambers evaluated for studies of macromolecular permeability in the human colon
    Conny Wallon
    Clinical Research Centre, University of Linkoping, Sweden
    Scand J Gastroenterol 40:586-95. 2005
    ..Endoscopic biopsies in Ussing chambers have been introduced as a means of studying secretion and transepithelial permeability, but have not been evaluated for studies of protein antigen uptake in human intestine...
  25. ncbi Smooth muscle cholinergic denervation hypersensitivity in diverticular disease
    Mark Golder
    Academic Department of Surgery, Barts and the London School of Medicine and Dentistry, Whitechapel, London, UK
    Lancet 361:1945-51. 2003
    ..We aimed to investigate the role of smooth muscle and neural cholinergic activity in the pathogenesis of this disease...
  26. ncbi One-stage sigmoid colon resection for perforated sigmoid diverticulitis (Hinchey stages III and IV)
    Sven Richter
    Clinic of General, Visceral, Vascular, and Pediatric Surgery, University Hospital of the Saarland, Kirrberger Strasse, D-66421 Homburg/Saar, Germany
    World J Surg 30:1027-32. 2006
    ....
  27. ncbi Infarction of the sigmoid colon secondary to giant cell arteritis
    M A Trimble
    Rheumatology (Oxford) 41:108-10. 2002
  28. ncbi Left pneumothorax secondary to colonoscopic perforation of the sigmoid colon: a case report
    Federico Lovisetto
    Dipartimento di Scienze Chirurgiche, Facolta di Medicina, University of Pavia, Italy
    Surg Laparosc Endosc Percutan Tech 17:62-4. 2007
    ..and subsequently an exploratory laparoscopy was performed, during which air was found in the subserosa of the sigmoid colon and in the mesosigmoid secondary to perforation of a sigmoid diverticulum...
  29. ncbi Sigmoid colon is an unexpected organ at risk in brachytherapy for cervix cancer
    Hoda Al-Booz
    The Department of Clinical Oncology, Bristol Haematology and Oncology Centre, Bristol, United Kingdom
    J Egypt Natl Canc Inst 18:156-60. 2006
    ..RESULTS: We found the sigmoid colon to be a relatively immobile structure that repeatedly received doses in excess of 70% of the intended point A ..
  30. ncbi Primary vs. secondary anastomosis after sigmoid colon resection for perforated diverticulitis (Hinchey Stage III and IV): a prospective outcome and cost analysis
    M K Schilling
    Department of Visceral and Transplantation Surgery, University of Bern, Switzerland
    Dis Colon Rectum 44:699-703; discussion 703-5. 2001
    PURPOSE: Our hypothesis was that in patients with perforated sigmoid colon diverticulitis and peritonitis (Hinchey Stage III and IV) a one-stage sigmoid colon resection is safe and cost effective when performed by an experienced ..
  31. ncbi [Ultrasonographic assessment of sigmoid colon in patients with irritable bowel syndrome]
    Hiroaki Kusunoki
    Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School
    Nippon Rinsho 64:1461-6. 2006
    ..factors may play a role in the pathogenesis of irritable bowel syndrome (IBS), the function of sigmoid colon has been reported as a major pathogenesis of IBS...
  32. ncbi [Pneumatosis coli complicated with necrosis and perforation wall of sigmoid colon and diffuse peritonitis]
    Robert Zimoch
    Oddział Chorób Wewnetrznych Zespołu Publicznych Zakładów Opieki Zdrowotnej w Miliczu
    Pol Arch Med Wewn 115:361-5. 2006
    ..They occur more frequently in the left than in the right colon. We show a rare case of pneumatosis coli which was compicated of necrosis sigmoid, perforation and diffuse peritonitis...
  33. ncbi Image-based three-dimensional treatment planning of intracavitary brachytherapy for cancer of the cervix: dose-volume histograms of the bladder, rectum, sigmoid colon, and small bowel
    Robert Y Kim
    Department of Radiation Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham, 1824 6th Avenue South, Birmingham, AL 35249, USA
    Brachytherapy 6:187-94. 2007
    The purpose of this study was to evaluate dose-volume histograms (DVHs) of bladder, rectum, sigmoid colon, and small bowel using image-based three-dimensional treatment planning for intracavitary brachytherapy.
  34. ncbi Vaginal reconstruction utilizing sigmoid colon: Complications and long-term results
    J Kellogg Parsons
    Division of Pediatric Urology, The James Buchanan Brady Urological Institute, Department of Surgery, The Johns Hopkins Hospital, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    J Pediatr Surg 37:629-33. 2002
    BACKGROUND/PURPOSE: The use of sigmoid colon segments to repair congenital deformities of the vagina is well established. There are little data, however, on complications or functional results in these patients...
  35. ncbi Nitric oxide is involved in the relaxant effect of capsaicin in the human sigmoid colon circular muscle
    L Bartho
    Department of Pharmacology and Pharmacotherapy, University Medical School of Pecs, Szigeti u 12, 7643 Pecs, Hungary
    Naunyn Schmiedebergs Arch Pharmacol 366:496-500. 2002
    The relaxant effect of capsaicin (300 nM) has been studied on mucosa-free circular strips of the human sigmoid colon in vitro...
  36. ncbi Surgical removal of an intrauterine device perforating the sigmoid colon: a case report
    Raul Mederos
    Department of General Surgery, Mount Sinai Medical Center, 4300 Alton Road, Miami Beach, FL 33140, USA
    Int J Surg 6:e60-2. 2008
    Intrauterine devices (IUDs) are among the most common contraceptive methods in the world, but have been associated with extrauterine dislocation and bowel perforation. We report a case of an IUD perforation of the sigmoid colon.
  37. ncbi [Perforation of the sigmoid colon secondary to acetabular fracture]
    J Proust
    , , 2, avenue Martin-Luther-King, 87042 Limoges Cedex
    Rev Chir Orthop Reparatrice Appar Mot 90:573-6. 2004
    ..Imaging provides clear evidence for avoiding late diagnosis and life-threatening situations...
  38. ncbi Laparoscopic closure for perforation of the sigmoid colon by endoscopic linear stapler
    K Hayashi
    First Department of Surgery, Shinshu University, Nagano, Japan
    Surg Laparosc Endosc 6:411-3. 1996
    ..Laparoscopic closure for perforation of the sigmoid colon caused by diagnostic colonoscopy is described...
  39. ncbi Migration of an intrauterine contraceptive device to the sigmoid colon: a case report
    U S Nceboz
    Celal Bayar University School of Medicine, Department of Obstetrics and Gynecology, Manisa, Turkey
    Eur J Contracept Reprod Health Care 8:229-32. 2003
    ..Although perforation of the uterus by an IUD is not uncommon, migration to the sigmoid colon is extremely rare. Here, we report a case of migration of an IUD to the sigmoid colon...
  40. ncbi Occult transfixation of the sigmoid colon by suprapubic catheter
    Miles D Witham
    Section of Ageing and Health, Ninewells Hospital, Dundee DD1 9SY, UK
    Age Ageing 31:407-8. 2002
    ..One day after the catheter was changed, he passed faeculent material in the catheter and became unwell with abdominal pain. The catheter tip was visible per rectum...
  41. ncbi Cervical surgical emphysema: rare presentation of a sigmoid colon retroperitoneal perforation with abscess rupture through the lumbar triangle of Petit
    L Zentner
    Ballarat Base Hospital, Ballarat, Victoria, Australia
    Australas Radiol 51:B140-3. 2007
    A retroperitoneal sigmoid colon perforation presenting with cervical surgical emphysema secondary to abscess rupture through the lumbar triangle of Petit into the posterior paraspinal muscle compartment has not been previously described...
  42. ncbi Mucinous adenocarcinoma arising in a neovagina using the sigmoid colon thirty years after operation: a case report
    H Hiroi
    Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    J Surg Oncol 77:61-4. 2001
    ..CASE: A neovagina was constructed using the sigmoid colon at the age of 23 for congenital agenesis of the vagina, Rokitansky-Küster-Hauser syndrome...
  43. ncbi Hand-assisted laparoscopic sigmoid colectomy: helping hand or hindrance?
    Y J Chang
    Department of Colon and Rectal Surgery, Lahey Clinic, 41 Mall Road, Burlington, MA 01805, USA
    Surg Endosc 19:656-61. 2005
    ..Therefore, we compared the outcome of patients undergoing hand-assisted laparoscopic sigmoid resection (HALSR) to that of those undergoing laparoscopic sigmoid resection (LSR)...
  44. ncbi Modified Soave procedure through the posterior sagittal approach for Hirschsprung's disease
    Nguyen Thanh Liem
    Surgical Department, National Hospital of Pediatrics, 18 879 Lathanh Road, Hanoi, Vietnam
    J Pediatr Surg 40:547-50. 2005
    ..The objective of this study is to describe the surgical technique and clinical results of a modified Soave procedure through the posterior sagittal approach (PSAP) for Hirschsprung's disease...
  45. ncbi Colorectal intervention as part of surgery for patients with gynaecological malignancy
    A Bedirli
    Division of Colorectal Surgery, University of Gazi, School of Medicine, Ankara, Turkey
    Colorectal Dis 7:228-31. 2005
    ..This study was conducted to determine the indications for and outcome of colorectal intervention in patients with advanced gynaecological malignancy...
  46. ncbi Preserving the superior rectal artery in laparoscopic sigmoid resection for complete rectal prolapse
    R Bergamaschi
    National Center for Advanced Laparoscopic Surgery, Saint Olav University Hospital, Trondheim, Norway
    Acta Chir Iugosl 51:53-5. 2004
    ..The division of the mesorectum at the rectosigmoid junction seems not necessary, and its sparing should therefore be considered as it may contain anastomotic leak rates...
  47. ncbi Resection rectopexy for external rectal prolapse reduces constipation and anal incontinence
    E Johnson
    Department of Gastroenterological Surgery, Ulleval University Hospital, Oslo, Norway
    Scand J Surg 96:56-61. 2007
    ..The main aim was to examine constipation and anal incontinence in patients before and after resection for external rectal prolapse...
  48. ncbi [Surgical strategies in the treatment of acute diverticular disease--a retrospective analysis of surgical patients at the hospital "Städtisches Klinikum Brandenburg an der Havel"]
    M Kautzsch
    Klinik für Allgemein und Viszeralchirurgie, Städtisches Klinikum Brandenburg a d Havel, Brandenburg
    Zentralbl Chir 133:61-7. 2008
    ..The frequency of use of the various therapeutic concepts and their success rates were studied in our clinic...
  49. ncbi Intraoperative colonoscopy for anastomosis assessment in laparoscopically assisted left-sided colon resection: is it worthwhile?
    Monika Lanthaler
    Department of General and Transplant Surgery Innsbruck Medical University Hospital, Innsbruck, Austria
    J Laparoendosc Adv Surg Tech A 18:27-31. 2008
    ..The aim of our study was to evaluate the use of intraoperative colonoscopy in laparoscopically assisted left-sided colon resection for the assessment of anastomosis...
  50. ncbi [Rectosigmoidectomy and end to end coloanal anastomosis with mechanical stapler for treatement of Hirschsprung disease]
    J Gaztambide Casellas
    , Hospital Universitario Materno Infantil Carlos Haya,
    Cir Pediatr 17:61-4. 2004
    ..The anastomosis is located in and extraperitoneal position, with a minimum risk of peritoneal involvement in case of anastomotic leakage. The patients presented a fast recovery, a minimum of complications and good functional result...
  51. ncbi Laparoscopic sigmoid and rectal resection using an electrothermal bipolar vessel sealing device
    Jyrki Kössi
    Department of Surgery, Paijat Hame Central Hospital, Lahti, Finland
    J Laparoendosc Adv Surg Tech A 17:719-22. 2007
    ..The aim of the present study was to evaluate the suitability of the device for laparoscopic colonic surgery...
  52. ncbi Functional outcomes of two types of subtotal colectomy for slow-transit constipation: ileosigmoidal anastomosis and cecorectal anastomosis
    Ye Feng
    Department of Colorectal Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
    Am J Surg 195:73-7. 2008
    ..The aim of the study was to compare the functional outcomes of subtotal colectomy with cecorectal anastomosis (CRA) with those of subtotal colectomy with ileosigmoidal anastomosis (ISA) in patients with severe slow-transit constipation...
  53. ncbi [Intestinal endometriosis: an obscure cause of cyclic rectal bleeding]
    C Sciume
    Universita degli Studi di Palermo, Dipartimento di Chirurgia Generale, d Urgenza e dei Trapianti d organo, Unità Operativa di Chirurgia Generale ad Indirizzo Toracico
    Ann Ital Chir 75:379-84; discussion 385. 2004
    ..Authors report their experience about a case of intestinal endometriosis that lead cyclic and recurrent rectal bleeding in a fertile-age woman...
  54. ncbi Rectovaginal fistula following double-stapling anastomosis in low anterior resection for rectal cancer
    Norifumi Tsutsumi
    Department of Surgery, Sawara Hospital, Fukuoka, Japan
    Hepatogastroenterology 54:1682-3. 2007
    ..Therefore, this complication must be kept in mind, and a minimal-sized fistula can be treated conservatively without a diverting colostomy or other surgical procedures...
  55. ncbi Early prediction of anastomotic leakage after colorectal surgery by measuring peritoneal cytokines: prospective study
    Burak Uğraş
    Department of General Surgery, Istanbul Medical Faculty, Istanbul University, 34093 Capa, Istanbul, Turkey
    Int J Surg 6:28-35. 2008
    ..Anastomotic leakage (AL) is a major cause of postoperative mortality and morbidity in colorectal surgery. We investigated the early prediction of peritoneal cytokine levels in developing AL after colorectal surgery...
  56. ncbi A sessile colonic polyp showing striking morphological changes within a 2-month period
    H Nakamura
    Department of Gastroenterology, Chofu Surgical Clinic, Tokyo, Japan
    Endoscopy 39:E279-80. 2007
  57. ncbi [Insufficient anastomoses in sigmoideal and rectal resections. A retrospective study conducted in a surgical clinic in Hradec Králové]
    P Motycka
    Chirurgická klinika LF UK v Hradci Králové a FN Hradec Králové
    Rozhl Chir 86:17-23. 2007
    ..Anastomotic insufficiency is the primary cause of postoperative morbidity and mortality following resection procedures of the large intestine and rectum...
  58. ncbi Resection of mesenteric inflammatory veno-occlusive disease causing ischemic colitis
    Philip Bao
    Department of General Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    J Gastrointest Surg 9:812-7. 2005
    ..This report substantiates resolution of the inflammatory process after resection, colostomy, and reanastomosis. We review the literature and make conclusions regarding the clinical management of this disease...
  59. ncbi Risk factors for anastomotic leak after recto-sigmoid resection for ovarian cancer
    Debra L Richardson
    Department of Obstetrics and Gynecology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Gynecol Oncol 103:667-72. 2006
    ..3, 95% CI 1.37-38.87). CONCLUSIONS: Low serum albumin is associated with an increased risk of anastomotic leak after RS resection for OC. Patients with a low albumin level may benefit from a protective diverting colostomy/ileostomy...
  60. ncbi Laparoscopic D3 lymph node dissection with preservation of the superior rectal artery for the treatment of proximal sigmoid and descending colon cancer
    Michiya Kobayashi
    Department of Human Health and Medical Sciences, Kochi Medical School, Nankoku, Japan
    J Laparoendosc Adv Surg Tech A 17:461-6. 2007
    In this paper we report a technique for laparoscopic lymph node (LN) dissection for descending and proximal sigmoid colon cancer with the preservation of the superior rectal artery (SRA) to maintain the blood supply to the distal sigmoid ..
  61. ncbi [Value of laparoscopic surgery in elective colorectal surgery with "fast-track"-rehabilitation]
    T Junghans
    Universitätsklinik für Allgemein, Visceral, Gefäss und Thoraxchirurgie, Universitatsmedizin Berlin, Charite Campus Mitte, Berlin
    Zentralbl Chir 131:298-303. 2006
    ..Whether these benefits may also occur when all patients are treated with multimodal "fast-track"-rehabilitation programs is questionable...
  62. ncbi Laparoscopic removal of an intrauterine device perforating the sigmoid colon: a case report and review of the literature
    Esmond Chi
    Division of Colorectal Surgery, Loma-Linda Medical Center, Los Angeles, California, USA
    Am Surg 71:1055-7. 2005
    ..Endoscopic tattooing and laparoscopy was used to identify the colonic site and facilitate extraction by colonic resection. A review of the literature and discussion of laparoscopic management of this complication is presented...
  63. ncbi A modified sigma-rectum pouch (Mainz pouch II) technique: analysis of outcomes and complications on 220 patients
    Jovan B Hadzi-Djokic
    Institute of Urology and Nephrology, Clinic of Urology, Belgrade, and Clinical Center Nis, Clinic of Urology, Nis, Serbia and Montenegro
    BJU Int 97:587-91. 2006
    ..To evaluate the safety and efficacy of a modified technique for a sigma-rectum pouch (Mainz pouch II)...
  64. ncbi [Laparoscopic surgery in colorectal diseases]
    E Balen
    Servicio de Cirugia General, Hospital de Navarra, Pamplona
    An Sist Sanit Navar 28:67-80. 2005
    ..A description is given of the details of the surgical technique of right and left colectomies, laparoscopic resections of the rectum and of total colectomy...
  65. ncbi Impact of new technologies on the clinical and functional outcome of Altemeier's procedure: a randomized, controlled trial
    Paolo Boccasanta
    Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, IRCCS Foundation, 1st Department of General Surgery, University of Milan, Milan, Italy
    Dis Colon Rectum 49:652-60. 2006
    ....
  66. ncbi Feasibility of single-stage resection and primary anastomosis in patients with acute noncomplicated sigmoid volvulus
    Alper Akcan
    Department of General Surgery, Erciyes University School of Medicine, Kayseri, Turkey
    Am J Surg 193:421-6. 2007
    ..The management of sigmoid volvulus remains controversial. The aim of this study was to evaluate the feasibility of treating sigmoid volvulus by using a single-stage resection and anastomosis versus a 2-stage approach...
  67. ncbi [Open surgery of the rectum]
    W Hohenberger
    Chirurgische Klinik, Universitatsklinikum Erlangen
    Chirurg 78:739-47. 2007
    ....
  68. ncbi Laparoscopic sigmoid resections for diverticulitis complicated by abscesses or fistulas
    Christina Zapletal
    Department of Surgery, Johann Wolfgang Goethe University, Theodor Stern Kai 7, 60590, Frankfurt Main, Germany
    Int J Colorectal Dis 22:1515-21. 2007
    ..Therefore, we analysed our results of laparoscopic sigmoidectomies concerning intraoperative course, conversion rate, morbidity and hospital stay in RD and CD...
  69. ncbi Colonic resection in the setting of damage control laparotomy: is delayed anastomosis safe?
    Preston R Miller
    Department of Surgery, Wake Forest University, Winston Salem, North Carolina 27157, USA
    Am Surg 73:606-9; discussion 609-10. 2007
    ..To our knowledge, this represents the first reported series of DA after DCL, an area in which further work is needed to carefully define indications for the safe application of this concept...
  70. ncbi Laparoscopic reversal of Hartmann's rectosigmoidectomy
    S Slawik
    Department of Colorectal Surgery, North Bristol NHS Trust, Frenchay Hospital, Bristol, UK
    Colorectal Dis 10:81-3. 2008
    ..The aim of this study was to analyse the outcome of laparoscopic restoration of bowel continuity post Hartmann's procedure...
  71. ncbi Outcome after rectum or sigmoid resection: a review for gynecologists
    Maria Lorena Ret Dávalos
    Department of Obstetrics and Gynecology, University Hospital Gasthuisberg, Katholieke Universiteit Leuven, Leuven, Belgium
    J Minim Invasive Gynecol 14:33-8. 2007
    ..This seems to be important in making the decision to perform a discoid or a segmental bowel resection for severe endometriosis...
  72. ncbi Polybacterial pyomyositis following laparoscopic colectomy for complicated diverticulosis
    Hang Korng Ea
    Service de médecine interne et rhumatologie, Groupe Hospitalier Diaconesses Croix Saint Simon, 125 rue d Avron, 75020 Paris, France
    Joint Bone Spine 74:653-5. 2007
    ..We report a case of diffuse subacute muscle infection caused by enteric bacteria, diagnosed two months after laparoscopic colectomy for a sigmoid abscess and successfully treated with antibiotics alone...
  73. ncbi Risk factors for clinical anastomotic leakage following the resection of sigmoid and rectal cancer
    Giedre Rudinskaite
    Department of Surgery, Kaunas University of Medicine, Eiveniu 2, 50009 Kaunas, Lithuania
    Medicina (Kaunas) 41:741-6. 2005
    ..anastomosis, 78--low anterior resection of rectum, 67--high anterior resection of rectum and 103--resection of sigmoid colon with colorectal anastomosis. Preoperative radiotherapy was performed on 61 patients...
  74. ncbi Pelvic cytoreduction with rectosigmoid resection
    Margrit M Juretzka
    Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
    Gynecol Oncol 104:40-4. 2007
  75. ncbi [Rectosigmoid endometriosis]
    A Bouhmidi
    Rev Esp Enferm Dig 98:797-8. 2006
  76. ncbi Defunctioning stoma reduces symptomatic anastomotic leakage after low anterior resection of the rectum for cancer: a randomized multicenter trial
    Peter Matthiessen
    Department of Surgery, Orebro University Hospital, Orebro, Sweden
    Ann Surg 246:207-14. 2007
    ....
  77. ncbi [Results of sigma resection in acute complicated diverticulitis : method and time of surgical intervention]
    J P Ritz
    Chirurgische Klinik I, Abteilung für Allgemein, Gefäss und Thoraxchirurgie, Charite Universitatsmedizin Berlin, Hindenburgdamm 30, 12200, Berlin, Deutschland
    Chirurg 79:753-8. 2008
    ..The aim of this study was to check the results of laparoscopic sigmoid resection for sigmoid diverticular disease with respect to stage of inflammation and time of surgical intervention...
  78. ncbi [Amyloidosis induced colonic stricture. The first symptom of myeloma multiplex. A case report]
    Anita Annahazi
    Szegedi Tudomanyegyetem, Általános Orvostudományi Kar, I Belgyógyászati Klinika
    Orv Hetil 149:1181-5. 2008
    ..Colonoscopy revealed a circular narrowing of the sigmoid colon suggesting malignancy...
  79. ncbi [Utility of sigmoid intramucosal pH in the early diagnosis of ischemic colitis after aorta surgery]
    M Portas González
    Servicio de Anestesiologia, Reanimacion y Terapeutica del Dolor, Hospital General Universitario Gregorio Maranon, C Doctor Esquerdo 46, 28007 Madrid
    Rev Esp Anestesiol Reanim 49:160-2. 2002
    ..The patient died from multiorgan failure 48 hours after surgery. Ischemic colitis is a severe complication of aortic surgery. Sigmoid pHi monitoring is non-invasive and highly useful for the early diagnosis of ischemic colitis...
  80. ncbi Primary transanal rectosigmoidectomy for Hirschsprung's disease: Preliminary results in the initial 33 cases
    Y Gao
    Department of Pediatric Surgery, The Second Hospital of Xi'an Jiaotong University, Xi'an, P.R. China
    J Pediatr Surg 36:1816-9. 2001
    ..CONCLUSIONS: Primary transanal rectosigmoidectomy for HD is logical and associated with excellent early results. A long-term follow-up is required to determine bowel functions. J Pediatr Surg 36:1816-1819...
  81. ncbi Modified transanal rectosigmoidectomy for Hirschsprung's disease: clinical and manometric results in the initial 20 cases
    Fabio Luis Peterlini
    , , Brazil
    J Pediatr Surg 38:1048-50. 2003
    ..The incidence of complications in our series was 10%. CONCLUSIONS: During the follow-up period of 29 months, all patients had normal bowel movements and normal anorectal manometric pressure profiles...
  82. ncbi Histopathological extent of rectal invasion by rectovaginal endometriosis
    A Kavallaris
    Department of Obstetrics and Gynecology, Friedrich Schiller University, Bachstrasse 18, 07740 Jena, Germany
    Hum Reprod 18:1323-7. 2003
    ..Partial bowel resection indicates the depth and multifocality of endometriosis affecting the recto-sigmoid colon. Such extensive surgery appears justified by the extent of the lesions and the long-term relief of symptoms ..
  83. ncbi Laparoscopic mobilization of the rectosigmoid and excision of the obliterated cul-de-sac
    Jackie Hollett-Caines
    Department of Obstetrics and Gynecology, University of Western Ontario, London, Canada
    J Am Assoc Gynecol Laparosc 10:190-4. 2003
    ..Some patient variables may give higher rates of success for pregnancy than others...
  84. ncbi Z-shaped anastomosis for the treatment of a benign rectosigmoid stricture
    Akira Furuichi
    Department of Surgery II, Nagasaki University School of Medicine, Nagasaki, Japan
    J Pediatr Surg 38:616-8. 2003
    ..Based on our experience, Z-shaped anastomosis appears to be an excellent treatment not only for Hirschsprung's disease but also for benign rectosigmoid stricture...
  85. ncbi Determinants of recurrence after sigmoid resection for uncomplicated diverticulitis
    Klaus Thaler
    Department of Colorectal Surgery, Cleveland Clinic Florida, 2950 Cleveland Clinic Boulevard, Weston, FL 33331, USA
    Dis Colon Rectum 46:385-8. 2003
    ..12, 14.96). CONCLUSION: Colorectal (rather than colosigmoid) anastomosis was the single predictor of lower recurrence rates after elective sigmoid resection for uncomplicated diverticulitis...
  86. ncbi Advantages of laparoscopic colectomy in older patients
    Anthony J Senagore
    Department of Colorectal Surgery, Minimally Invasive Surgery Center, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Arch Surg 138:252-6. 2003
    ..We compared short-term outcomes in age-matched cohorts of patients undergoing laparoscopic vs open segmental colectomy managed with the Controlled Rehabilitation With Early Ambulation and Diet program...
  87. ncbi Transanal one-stage endorectal pull-through for Hirschsprung's disease in infants and children
    Sumate Teeraratkul
    Pediatric Surgery Unit, Department of Surgery, Ramathibodi Hospital, Mahidol University, Rajathavi, Bangkok, Thailand
    J Pediatr Surg 38:184-7. 2003
    ..The limitation of this approach is that retroperitoneal fixation of the descending colon could not be dissected by the transanal route...
  88. ncbi [Laparoscopic sigmoid resection]
    F Corcione
    UOC di Chirurgia Generale e Centro di Chirurgia Laparoscopica, A O Monaldi, Azienda Ospedaliera di Rilievo Nazionale e di Alta Specializzazione, Napoli, Italy
    Minerva Chir 58:509-13. 2003
    ....
  89. ncbi Surgical management of acute sigmoid diverticulitis
    N P Blair
    Division of General Surgery, Royal Columbian Hospital, 210-245 E. Columbia Street, New Westminster, British Columbia, Canada V3L 3W4
    Am J Surg 183:525-8. 2002
    ..CONCLUSIONS: The practice of resection and primary anastomosis for acute sigmoid diverticulitis at the Royal Columbian Hospital has an acceptable morbidity and mortality...
  90. ncbi [Sigmoidoperianal fistula associated with diverticulitis and Cul de Sac situation--diagnostics and therapy]
    G Weyand
    Abteilung Koloproktologie Ltd Arzt, St Josefs Hospital Wiesbaden
    Zentralbl Chir 127:622-5. 2002
    ..The sigmoidoperianal fistula must be taken into account as a differential diagnosis of a recalcitrant high perianal fistula...
  91. ncbi Experience with laparoscopic medial and lateral dissection of the rectosigmoid for cancer
    Daniel Bacal
    World J Surg 27:1337-8; author reply 1338. 2003
  92. ncbi Use of an implantable marker for rapid intraoperative localization of nonpalpable tumors: a pilot study in a swine colorectal model
    C J Sonnenday
    Department of Surgery, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA
    Surg Endosc 17:1927-31. 2003
    ..This technology may have important implications in the surgical management of nonpalpable tumors and in applications of interventional radiology...
  93. ncbi Rectal prolapse as initial clinical manifestation of colon cancer
    C W Chen
    Division of Colon and Rectal Surgery, Department of Surgery, Tri Service General Hospital, National Defense Medical Center, Taipei, Taiwan
    Z Gastroenterol 46:348-50. 2008
    ..We describe the case of a 75-year-old woman who was diagnosed as having adenocarcinoma of the sigmoid colon after presenting with complete rectal prolapse...
  94. ncbi Fecoflowmetric profiles in postoperative patients with Hirschsprung's disease
    Minoru Yagi
    Department of Pediatric Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata City, Niigata 951 8510, Japan
    J Pediatr Surg 40:551-4. 2005
    ..The objective of this study is to evaluate the anorectal function from the viewpoint of fecoflowmetry in postoperative patients with Hirschsprung's disease (HD)...
  95. ncbi Persistent symptoms after elective sigmoid resection for diverticulitis
    Bernhard Egger
    Department of Visceral and Transplantation Surgery, University of Bern, Bern, Switzerland
    Dis Colon Rectum 51:1044-8. 2008
    ..This study was designed to determine the incidence and pattern of persistent symptoms and their association with peroperative parameters...
  96. ncbi Colorectal anastomotic stenosis after elective laparoscopic sigmoidectomy for diverticular disease: a prospective evaluation of 68 patients
    Patrick Ambrosetti
    Clinique Générale Beaulieu, 4, rue Emile Yung, 1205, Geneva, Switzerland
    Dis Colon Rectum 51:1345-9. 2008
    ..This prospective study was designed to find the incidence of symptomatic anastomotic stenosis after elective laparoscopic sigmoidectomy for diverticular disease...
  97. ncbi Laparoscopic treatment of enteric fistulas
    J P Regan
    Division of Laparoscopic Surgery, Department of Surgery, Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1103, New York, NY 10029 6574, USA
    Surg Endosc 18:252-4. 2004
    ..However, few data exist regarding the laparoscopic management of enteric fistulas from diverticular and Crohn's disease...
  98. ncbi [Should early feeding be permitted following elective colorectal resection?]
    A Alves
    Service de Chirurgie Digestive, Hopital Lariboisiere, 2, rue Ambroise Pare, 75010, Paris, France
    Ann Chir 129:94-5. 2004
  99. ncbi Gastrointestinal transit after laparoscopic versus open colonic resection
    L Basse
    Department of Surgical Gastroenterology, Copenhagen University Hospital, Hvidovre, Denmark
    Surg Endosc 17:1919-22. 2003
    ..Gastrointestinal transit after colonic resection with laparoscopy or laparotomy was assessed...
  100. ncbi Mainz Pouch II technique: 10 years' experience
    S Pahernik
    Department of Urology, Mainz University Medical School, Mainz, Germany
    BJU Int 93:1037-42. 2004
    ..The Mainz Pouch II ureterosigmoidostomy is simple and reliable as a viable alternative for continent urinary diversion in selected patients...
  101. ncbi Multimedia article. Laparoscopic-assisted rectosigmoidectomy with ileal loop interposition. Surgical treatment of chagasic megacolon
    Eloy Espin-Basany
    Colorectal Surgery Unit, Hospital Valle de Hebron, Autonomous University of Barcelona, Barcelona, Spain
    Dis Colon Rectum 51:1421. 2008
    ..Recently a report of 147 patients treated with an open rectosigmoidectomy with an ileal loop interposition showed a low rate of complications (8.5 percent) and recurrence (3.1 percent).1..

Research Grants71

  1. NEUROENDOCRINE ALTERATIONS IN FIBROMYALGIA AND IBS
    Lin Chang; Fiscal Year: 2007
    ....
  2. Colon Barrier Breakdown in the Elderly
    James Mullin; Fiscal Year: 2005
    ..2: These same patient volunteers will be contributing biopsies of the ascending colon, descending colon and sigmoid colon during their colonoscopy...
  3. Calcium/Vitamin D, Biomarkers & Colon Polyp Prevention
    Roberd Bostick; Fiscal Year: 2007
    ..colonoscopy; biopsies of normal appearing mucosa will also be taken from three colon sites (rectum, mid- sigmoid colon, and proximal ascending colon) during follow-up colonoscopies...
  4. GENETIC ANALYSIS OF HIRSCHSPRUNG DISEASE
    Aravinda Chakravarti; Fiscal Year: 2001
    ..and beyond (long segment HSCR), the splenic flexure and the descending colon (short segment HSCR), or the sigmoid colon only (classic HSCR)...
  5. GENETIC ANALYSIS OF HIRSCHSPRUNG DISEASE
    Aravinda Chakravarti; Fiscal Year: 2007
    ..beyond (long segment: L-HSCR), the splenic flexure and the descending colon (short segment: S-HSCR), or the sigmoid colon only (classic HSCR)...
  6. Aspirin, UGT1A6 Genotype, and Colon Gene Expression
    Johanna Lampe; Fiscal Year: 2006
    ..in colonic gene expression will be determined using cDNA microarray analysis of biopsy RNA from the sigmoid colon and rectum and Bax and Bcl-2 expression in the colonic crypts will be measured by immunohistochemistry...
  7. Relex Pathways Controlling Intestinal Motility
    TERENCE KEITH SMITH; Fiscal Year: 2010
    ..In addition, we have found that the monkey sigmoid colon, which is our translation model, has motor patterns that are similar to those in the guinea-pig colon and ..
  8. Relex Pathways Controlling Intestinal Motility
    Terence Smith; Fiscal Year: 2009
    ..In addition, we have found that the monkey sigmoid colon, which is our translation model, has motor patterns that are similar to those in the guinea-pig colon and ..
  9. Relex Pathways Controlling Intestinal Motility
    Terence Smith; Fiscal Year: 2009
    ..In addition, we have found that the monkey sigmoid colon, which is our translation model, has motor patterns that are similar to those in the guinea-pig colon and ..
  10. Aging and Cancer of the Colon
    STEVEN DUDAS; Fiscal Year: 2004
    ..In a cohort of colon cancer patients diagnosed with local, regional or distant adenocarcinoma of the sigmoid colon, we propose to determine with respect to age: levels of oxidative DNA damage, apoptotic activity and the ..
  11. Role of Progesterone in Colonic Muscle Dysfunction
    Jose Behar; Fiscal Year: 2007
    ..and pregnant guinea pigs, and in normal and PG treated human colonic muscle cells from free margins of the sigmoid colon of patients with adenocarcinoma and from female patients with colonic inertia and chronic constipation...
  12. CD8+TCell Antiretroviral Mechanisms in Lymphoid Tissue
    Elizabeth Connick; Fiscal Year: 2003
    ..IFN)-gamma production, tetramer staining, cytolysis, and apoptosis in peripheral blood, lymph node and sigmoid colon biopsies...
  13. NADPH oxidase-associated transition from Barrett's esophagus to adenocarcinoma
    Weibiao Cao; Fiscal Year: 2010
    ..This project is designed to find potential therapeutic targets to prevent this progression. ..
  14. NADPH oxidases-associated transition from Barrett's esophagus to adenocarcinoma
    Weibiao Cao; Fiscal Year: 2007
    ....
  15. Signal transduction in progression of Barretts esophagus
    Weibiao Cao; Fiscal Year: 2002
    ..4. Determine signaling pathways involved in the upregulation of COX-2 following acid exposure. 5. Determine whether IL-lb induces production of IL-6. ..
  16. CONTRACTILE SIGNAL TRANSDUCTION IN ULCERATIVE COLITIS
    Weibiao Cao; Fiscal Year: 2004
    ..To define inflammation, associated changes in motor function we will examine the circular muscle from the sigmoid colon from patient with active ulcerative colitis and compare it with muscle from disease-free margins of ..
  17. Treatment of Fear and Pain in Irritable Bowel Syndrome
    Bruce Naliboff; Fiscal Year: 2006
    ..abstract_text> ..
  18. Physiologic Characteristics of Traditional Chinese Medicine Based IBS Subgroups
    Bruce Naliboff; Fiscal Year: 2007
    ..Given the disappointing results with conventional approaches to multisystemic functional disorders like IBS, this may provide exciting insights and contributions to the classification and treatment of these challenging disorders. ..
  19. CORI: Consortium Expansion and Database Enhancement
    David Lieberman; Fiscal Year: 2004
    ....
  20. Inflamation and the Risk of Endometrial Cancer
    Akila Viswanathan; Fiscal Year: 2007
    ..This proposal will ensure that she will become an established independent investigator and a leading expert in gynecologic cancer epidemiology. ..
  21. NEUROENDOCRINE ALTERATIONS IN FIBROMYALGIA AND IBS
    Lin Chang; Fiscal Year: 2009
    ..abstract_text> ..
  22. NEUROENDOCRINE ALTERATIONS IN FIBROMYALGIA AND IBS
    Lin Chang; Fiscal Year: 2010
    ..abstract_text> ..
  23. NEUROENDOCRINE ALTERATIONS IN FIBROMYALGIA AND IBS
    Lin Chang; Fiscal Year: 2003
    ..The combination of experimental approaches should improve our understanding of the CNS mechanisms underlying functional pain syndromes. ..