appendix

Summary

Summary: A worm-like blind tube extension from the CECUM.

Top Publications

  1. ncbi Effect of fixation on brain and lymphoreticular vCJD prions and bioassay of key positive specimens from a retrospective vCJD prevalence study
    Jonathan D F Wadsworth
    MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK
    J Pathol 223:511-8. 2011
  2. ncbi Bacterial translocation in the normal human appendix parallels the development of the local immune system
    Jan Olaf Gebbers
    Institute of Pathology, Kantonsspital, CH 6000 Luzern 16, Switzerland
    Ann N Y Acad Sci 1029:337-43. 2004
  3. ncbi Detection of the normal appendix with low-dose unenhanced CT: use of the sliding slab averaging technique
    Seung Moon Joo
    Department of Radiology, Seoul National University Bundang Hospital, Republic of Korea
    Radiology 251:780-7. 2009
  4. ncbi Mucocele of the appendix
    J Ruiz-Tovar
    Department of Surgery, University Hospital Ramon y Cajal, Crta Colmenar Km 9, 100 28034, Madrid, Spain
    World J Surg 31:542-8. 2007
  5. pmc Accumulation of prion protein in tonsil and appendix: review of tissue samples
    David A Hilton
    Department of Histopathology, Derriford Hospital, Plymouth PL6 8DH
    BMJ 325:633-4. 2002
  6. ncbi Role of appendix and spleen in experimental colitis
    C F Krieglstein
    Department of Molecular and Cellular Physiology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130, USA
    J Surg Res 101:166-75. 2001
  7. ncbi Incarcerated vermiform appendix in a left-sided inguinal hernia
    S Breitenstein
    Department of Surgery, Kantonsspital Winterthur, 8401 Winterthur, Switzerland
    Hernia 9:100-2. 2005
  8. ncbi Biofilms in the large bowel suggest an apparent function of the human vermiform appendix
    R Randal Bollinger
    Department of Surgery, Duke University Medical Center, Box 2605, Durham, NC 27710, USA
    J Theor Biol 249:826-31. 2007
  9. ncbi The NANETS consensus guideline for the diagnosis and management of neuroendocrine tumors: well-differentiated neuroendocrine tumors of the Jejunum, Ileum, Appendix, and Cecum
    J Philip Boudreaux
    Department of Surgery, Louisiana State University Health Sciences Center, New Orleans, LA, USA
    Pancreas 39:753-66. 2010
  10. ncbi Update on the surgical approach to mucocele of the appendix
    Shubhada Dhage-Ivatury
    Department of Surgery, Howard University Medical School, and the Washington Cancer Institute, Washington, DC 20010, USA
    J Am Coll Surg 202:680-4. 2006

Research Grants

  1. Role of the kallikrein-kinin system in diabetic retinopathy
    Edward P Feener; Fiscal Year: 2012
  2. PTEN TUMOR SUPPRESSOR AND SIGNAL TRANSDUCTION
    RAMON E PARSONS; Fiscal Year: 2012
  3. VISUAL SCIENCES TRAINING PROGRAM
    Eric Pearlman; Fiscal Year: 2013
  4. Developing Physics-Based Virtual Simulation Technology for Natural Orifice Transl
    DANIEL BOUGERE JONES; Fiscal Year: 2013
  5. Lung VITamin D and OmegA-3 TriaL (Lung VITAL)
    Diane R Gold; Fiscal Year: 2013
  6. Targeting Galectin-1 with radiation in lung cancer
    QUYNH THU XUAN LE; Fiscal Year: 2013
  7. Regional Biocontainment Laboratory
    Charles Bailey; Fiscal Year: 2007
  8. Regulation of Organized Intestinal Lymphoid Tissues by TRANCE/RANKL
    Ifor R Williams; Fiscal Year: 2012
  9. EFFECT OF R1R2 OVER-EXPRESSION ON CARDIAC FUNCTION
    Michael Regnier; Fiscal Year: 2013
  10. Serotonergic Immunomodulation in Neuroinflammatory Disease
    CATHERINE ELIZABETH HAGAN; Fiscal Year: 2012

Detail Information

Publications302 found, 100 shown here

  1. ncbi Effect of fixation on brain and lymphoreticular vCJD prions and bioassay of key positive specimens from a retrospective vCJD prevalence study
    Jonathan D F Wadsworth
    MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK
    J Pathol 223:511-8. 2011
    ..Hilton et al (J Pathol 2004; 203: 733-739) found accumulation of abnormal prion protein in three formalin-fixed appendix specimens...
  2. ncbi Bacterial translocation in the normal human appendix parallels the development of the local immune system
    Jan Olaf Gebbers
    Institute of Pathology, Kantonsspital, CH 6000 Luzern 16, Switzerland
    Ann N Y Acad Sci 1029:337-43. 2004
    ..A physiological uptake of, or invasion by, bacteria may be instrumental (1) for tolerance induction against the indigenous flora and (2) for the stimulation and normal development of the GALT...
  3. ncbi Detection of the normal appendix with low-dose unenhanced CT: use of the sliding slab averaging technique
    Seung Moon Joo
    Department of Radiology, Seoul National University Bundang Hospital, Republic of Korea
    Radiology 251:780-7. 2009
    To determine the frequency of normal appendix visualization at low-dose (LD) unenhanced computed tomography (CT) performed with a 16- or 64-detector row scanner when images are reviewed by using the sliding slab averaging technique.
  4. ncbi Mucocele of the appendix
    J Ruiz-Tovar
    Department of Surgery, University Hospital Ramon y Cajal, Crta Colmenar Km 9, 100 28034, Madrid, Spain
    World J Surg 31:542-8. 2007
    Mucocele of the appendix is an infrequent event, representing 0.3%-0.7% of appendiceal pathology and 8% of appendiceal tumors. It is characterized by a located or diffuse distension of the appendix with a mucus-filled lumen.
  5. pmc Accumulation of prion protein in tonsil and appendix: review of tissue samples
    David A Hilton
    Department of Histopathology, Derriford Hospital, Plymouth PL6 8DH
    BMJ 325:633-4. 2002
  6. ncbi Role of appendix and spleen in experimental colitis
    C F Krieglstein
    Department of Molecular and Cellular Physiology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130, USA
    J Surg Res 101:166-75. 2001
    There is growing clinical evidence suggesting that certain secondary lymphoid tissues (e.g., appendix and spleen) contribute to the initiation and/or perpetuation of ulcerative colitis...
  7. ncbi Incarcerated vermiform appendix in a left-sided inguinal hernia
    S Breitenstein
    Department of Surgery, Kantonsspital Winterthur, 8401 Winterthur, Switzerland
    Hernia 9:100-2. 2005
    We report here of a patient with an incarcerated vermiform appendix occurring in a left-sided indirect inguinal hernia...
  8. ncbi Biofilms in the large bowel suggest an apparent function of the human vermiform appendix
    R Randal Bollinger
    Department of Surgery, Duke University Medical Center, Box 2605, Durham, NC 27710, USA
    J Theor Biol 249:826-31. 2007
    The human vermiform ("worm-like") appendix is a 5-10cm long and 0.5-1cm wide pouch that extends from the cecum of the large bowel...
  9. ncbi The NANETS consensus guideline for the diagnosis and management of neuroendocrine tumors: well-differentiated neuroendocrine tumors of the Jejunum, Ileum, Appendix, and Cecum
    J Philip Boudreaux
    Department of Surgery, Louisiana State University Health Sciences Center, New Orleans, LA, USA
    Pancreas 39:753-66. 2010
    Well-differentiated neuroendocrine tumors (NETs) of the jejunum, ileum, and appendix are also collectively known as midgut carcinoids. Similar to NETs in general, the diagnosed incidence of the midgut NETs is on the rise...
  10. ncbi Update on the surgical approach to mucocele of the appendix
    Shubhada Dhage-Ivatury
    Department of Surgery, Howard University Medical School, and the Washington Cancer Institute, Washington, DC 20010, USA
    J Am Coll Surg 202:680-4. 2006
  11. ncbi The most useful findings for diagnosing acute appendicitis on contrast-enhanced helical CT
    D Choi
    Department of Radiology, Kangbuk Samsung Hospital, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Acta Radiol 44:574-82. 2003
    ..To evaluate the most useful findings to look for in diagnosing acute appendicitis on contrast-enhanced helical CT...
  12. ncbi Endometriosis of the appendix presenting as acute appendicitis
    J J Khoo
    Department of Pathology, Sultanah Aminah Hospital, Jalan Skudai, Johor Bahru, Johor 80100, Malaysia
    Singapore Med J 45:435-6. 2004
    While endometriosis is fairly common, endometriosis of the appendix is a very rare occurrence. Correct pre-operative diagnosis is uncommon and definitive diagnosis is established by histology of the appendix...
  13. ncbi Preferential migration of CD62L cells into the appendix in mice with experimental chronic colitis
    S A Farkas
    Department of Surgery, University of Regensburg, Regensburg, Germany
    Eur Surg Res 37:115-22. 2005
    Clinical and experimental studies suggest that appendectomy can protect against development of ulcerative colitis and Crohn's disease. However, how T cells in the appendix affect the development of colitis has not been clarified.
  14. ncbi Right lower quadrant pain: value of the nonvisualized appendix in patients at multidetector CT
    Suvranu Ganguli
    Department of Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, USA
    Radiology 241:175-80. 2006
    To retrospectively determine the value of the nonvisualized appendix at multidetector computed tomography (CT) in patients with acute right lower quadrant pain in whom appendicitis was a consideration.
  15. ncbi The appendix on CT
    S Whitley
    Sunnybrook Health Sciences Center, Toronto, Ontario, Canada
    Clin Radiol 64:190-9. 2009
    ..This review will demonstrate the appearance of the normal appendix on computed tomography (CT) and its appearance in a range of inflammatory and neoplastic processes including ..
  16. ncbi Metallic foreign body in the appendix of 3-year-old boy
    Charles W Hartin
    Department of Surgery, Division of Pediatric Surgery, Women and Children s Hospital of Buffalo, State University of New York at Buffalo, Buffalo, NY 14222, USA
    J Pediatr Surg 43:2106-8. 2008
    ..However, when the foreign body becomes incarcerated in the appendix, a prophylactic appendectomy is recommended to prevent appendicitis...
  17. ncbi Terminal deoxynucleotidyl transferase-positive cells in spleen, appendix and branchial cleft cysts in pediatric patients
    Dennis P O'Malley
    Haematologica 91:1139-40. 2006
    ..In spleen, appendix and branchial cleft cysts the range of TdT-positivity was 0-13, 0-96 and 0-6 TdT+ cells/hpf, respectively...
  18. ncbi Creation of continence mechanisms (Mitrofanoff) without appendix: the Monti and spiral Monti procedures
    Jeffrey A Leslie
    Department of Urology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Urol Oncol 25:148-53. 2007
    ..Pediatric urologists have widely used this technique for years, especially when the appendix is either not available or suitable for use...
  19. ncbi Appendiceal endometriosis mimicking acute appendicitis
    V Tumay
    Department of General Surgery, Uludag University School of Medicine, Bursa, Turkey
    Acta Chir Belg 106:712-3. 2006
    ..Physical examination revealed rebound tenderness in the right iliac fossa. Her white blood cell count was 23300/mm3. We performed appendicectomy. The histopathological result was endometriosis of the appendix vermiformis.
  20. ncbi Multiple myenteric networks in the human appendix
    Menachem Hanani
    Hebrew University Hadassah Medical School, Mount Scopus, Jerusalem 91240, Israel
    Auton Neurosci 110:49-54. 2004
    The general histological organization of the appendix, including its innervation, is believed to be generally similar to that of the large intestine...
  21. ncbi Location of the appendix in the gravid patient: a re-evaluation of the established concept
    H Hodjati
    Department of General Surgery, Shiraz University of Medical Sciences, Shiraz, Iran
    Int J Gynaecol Obstet 81:245-7. 2003
    To determine the anatomical location of the appendix, as it may change during pregnancy.
  22. ncbi Intestinal schistosomiasis manifesting as colonic intussusception arising from a mucocele of the appendix: report of a case
    Mark T C Wong
    Department of General Surgery, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, Singapore
    Surg Today 38:664-7. 2008
    ..a case of intestinal schistosomiasis manifesting as colonic intussusception resulting from a mucocele of the appendix, caused by the obstruction of appendiceal outflow by schistosome egg-induced fibrosis...
  23. ncbi Prevalence of lymphoreticular prion protein accumulation in UK tissue samples
    David A Hilton
    Department of Histopathology, Derriford Hospital, Plymouth, UK
    J Pathol 203:733-9. 2004
    ....
  24. ncbi [Mucocele of the appendix and pseudomyxoma peritonei]
    A Fairise
    Service de Radiologie Adultes, CHU Nancy Brabois, Allee du Morvan, Vandoeuvre les Nancy Cedex, France
    J Radiol 89:751-62. 2008
  25. ncbi The nonvisualized appendix: incidence of acute appendicitis when secondary inflammatory changes are absent
    Paul Nikolaidis
    Department of Radiology, Northwestern University Feinberg School of Medicine, 676 N St Clair St, Ste 800, Chicago, IL 60611, USA
    AJR Am J Roentgenol 183:889-92. 2004
    The objective of our study was to assess the importance of nonvisualization of the appendix and its association with acute appendicitis on helical CT when secondary inflammatory changes are absent.
  26. ncbi [Isolated Crohn's disease of the appendix as a source of enterorrhagia]
    Sizenando Ernesto de Lima
    Hospital Samaritano, Sao Paulo, SP
    Arq Gastroenterol 41:60-3. 2004
    Crohn's disease confined to the appendix is relatively rare as a sole primary manifestation of the disease. Young people are more affected...
  27. ncbi [Burkitt's lymphoma of the appendix]
    L Bissen
    Service d Imagerie Medicale, CHU André Vésale ULB, Montigny le Tilleul, Belgique
    JBR-BTR 85:257-9. 2002
    ..This case emphasizes the importance of medical imaging to characterize appendicular lesions and to select the surgical technique. Accurate diagnosis was obtained histologically on resected specimen...
  28. ncbi Congenital absence of the cecal appendix. Case report
    Carlos Arturo Zetina-Mejía
    Hospital General de Querétaro SESEQS Servicio de Cirugía General Av 5 de Febrero 101, Col Virreyes, Queretaro, Mexico
    Cir Cir 77:407-10. 2009
    Agenesis of the vermiform appendix is very rare and was first described by Morgagni in 1718. The estimated incidence is 1/100,000 laparotomies performed for suspected appendicitis...
  29. ncbi Visualization rate and pattern of normal appendix on multidetector computed tomography by using multiplanar reformation display
    Ya Ting Jan
    Department of Radiology, Mackay Memorial Hospital, Taipei, Taiwan 10449, Province of China
    J Comput Assist Tomogr 29:446-51. 2005
    To evaluate the visualization rate and describe the morphologic pattern of the normal appendix on multidetector CT (MDCT) by using multiplanar reformation display.
  30. ncbi Acute abdomen associated with schistosomiasis of the appendix
    Chiara Gabbi
    Department of and Medical Specialties, University of Modena and Reggio Emilia, Modena, Italy
    Dig Dis Sci 51:215-7. 2006
  31. ncbi Are cecal wrap and fixation necessary for antegrade colonic enema appendicostomy?
    Antti Koivusalo
    Children s Hospital, Department of Paediatric Surgery, University of Helsinki, 00290 Helsinki, Finland
    J Pediatr Surg 41:323-6. 2006
    ..ACE) appendicostomy, cecal fixation on the inside of the abdominal wall and cecal wrap around the base of the appendix are often performed as an antireflux procedure...
  32. ncbi The appendix as a conduit for antegrade continence enemas in patients with anorectal malformations: lessons learned from 163 cases treated over 18 years
    Shawn J Rangel
    Department of Pediatric Surgery, Children s Hospital Boston, Harvard School of Medicine, Boston, MA 02115, USA
    J Pediatr Surg 46:1236-42. 2011
    ..The purpose of this study was to examine our experience with the ACE procedure using the appendix as a catheterizable conduit in children with anorectal malformations (ARMs).
  33. ncbi Laparoscopic-assisted Malone appendicostomy in the management of fecal incontinence in children
    Taiwo A Lawal
    Division of Pediatric Surgery, Department of Surgery, Colorectal Center for Children, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio 45229, USA
    J Laparoendosc Adv Surg Tech A 21:455-9. 2011
    ..We present our experience using this approach for fecal incontinence patients and technical modifications to reduce complications...
  34. pmc Role of appendix in the development of inflammatory bowel disease in TCR-alpha mutant mice
    A Mizoguchi
    Immunopathology Unit, Massachusetts General Hospital, Boston 02114, USA
    J Exp Med 184:707-15. 1996
    ..to play an important role in the development of chronic intestinal inflammation, we examined the changes in the appendix lymphoid follicle (ALF) and Peyer's patches (PP) in these mice...
  35. ncbi Mucocele of the appendix with magnetic resonance imaging findings
    M Puvaneswary
    Department of Medical Imaging, John Hunter Hospital, Newcastle, New South Wales, Australia
    Australas Radiol 50:71-4. 2006
    Mucocele of the appendix is a rare lesion caused by abnormal accumulation of mucus. Although preoperative diagnosis is important to avoid rupture of a mucocele, the diagnosis is often made at surgery...
  36. ncbi Precursor T-cell acute lymphoblastic leukemia/lymphoma involving the uterine cervix, myometrium, endometrium, and appendix
    Mark D Lyman
    Department of Pathology, Wilford Hall Medical Center, San Antonio, TX 78236 5300, USA
    Ann Diagn Pathol 6:125-8. 2002
    ..T-cell acute lymphoblastic leukemia/lymphoma (ALL) involving the uterine cervix, myometrium, endometrium, and appendix. The patient was a 38-year-old woman with a history of ALL who had been in remission for 4 years following ..
  37. ncbi Appendix is a priming site in the development of ulcerative colitis
    Mitsunobu Matsushita
    Third Department of Internal Medicine, Kansai Medical University, 10 15 Fumizono cho, Moriguchi, Osaka 570 8506, Japan
    World J Gastroenterol 11:4869-74. 2005
    The role of the appendix has been highlighted in the pathogenesis of ulcerative colitis (UC)...
  38. ncbi Role of the appendix in the pathogenesis of ulcerative colitis
    M Matsushita
    Third Department of Internal Medicine, Kansai Medical University, 2 3 1 Shinmachi, Hirakata, Osaka 573 1191, Japan
    Inflammopharmacology 15:154-7. 2007
    Although human appendix has been considered as a vestigial remnant, recent observations have focused attention on the role of the appendix in the pathogenesis of ulcerative colitis (UC)...
  39. ncbi Diverticulosis and diverticulitis of the appendix
    Badr AbdullGaffar
    Histopathology Department, Dubai Hospital, Dubai, United Arab Emirates
    Int J Surg Pathol 17:231-7. 2009
    Diverticulosis of the appendix is a relatively rare pathological finding. The majority are acquired pseudodiverticula. True congenital diverticula are very rare...
  40. ncbi Primary tuberculosis of the appendix in a young male patient: report of a case
    Nobuhisa Ito
    Department of Surgery, Fukuoka Tokushukai Hospital, 4 5 Sukukita, Kasuga, Fukuoka, 816 0864, Japan
    Surg Today 40:668-71. 2010
    ..response was found, and abdominal computed tomography showed a diffuse enlargement and wall thickening in the appendix. An ileocecal abscess and perforating appendicitis were suspected...
  41. ncbi Endometriosis of the vermiform appendix as an exceptional cause of acute perforated appendicitis during pregnancy
    J L Faucheron
    Department of Colorectal Surgery, University Hospital, Grenoble, France
    Colorectal Dis 10:518-9. 2008
    ..Most cases of endometriosis of the appendix are discovered as a result of incidental appendectomy...
  42. ncbi US features of the normal appendix and surrounding area in children
    Fraukje Wiersma
    Department of Radiology, Juliana Children s Hospital, Sportlaan 600, The Hague, The Netherlands
    Radiology 235:1018-22. 2005
    To evaluate prospectively the frequency of depiction with ultrasonography (US) of the appendix in children without clinical suspicion of acute appendicitis and to evaluate the US appearance of the normal appendix.
  43. ncbi Inflammatory appendix masses masquerading as pelvic tumours
    M P Hiorns
    Department of Radiology, The Royal London Hospital, London, UK
    Clin Radiol 57:70-3. 2002
  44. ncbi Value of routine histopathologic examination of three common surgical specimens: appendix, gallbladder, and hemorrhoid
    Varut Lohsiriwat
    Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Prannok Road, Bangkok, 10700, Thailand
    World J Surg 33:2189-93. 2009
    The purpose of this study was to assess the need for a routine histopathologic examination of three common surgical specimens (appendix, gallbladder, hemorrhoid) and its impact on the further management of the patients.
  45. ncbi The cecal appendix: one more immune component with a function disturbed by post-industrial culture
    Michel Laurin
    UMR 7207, CNRS MNHN UPMC, Centre de Recherches sur la Paléobiodiversité et les Paléoenvironnements, Museum national d histoire naturelle, Paris, France
    Anat Rec (Hoboken) 294:567-79. 2011
    This review assesses the current state of knowledge regarding the cecal appendix, its apparent function, and its evolution...
  46. ncbi Primary T-cell non-Hodgkin's malignant lymphoma of the appendix
    Y Kitamura
    Second Department of Pathology, Faculty of Medicine, Tottori University, Yonago, Japan
    Pathol Int 50:313-7. 2000
    A case of primary T-cell lymphoma of the appendix in an 84-year-old female was reported...
  47. ncbi The coexistence of low-grade mucinous neoplasms of the appendix and appendiceal diverticula: a possible role in the pathogenesis of pseudomyxoma peritonei
    L W Lamps
    Department of Pathology, University of Arkansas for Medical Sciences, Little Rock 72205, USA
    Mod Pathol 13:495-501. 2000
    ..Either mechanism might allow low-grade mucinous neoplasms to penetrate the appendiceal wall more easily...
  48. ncbi Unusual duplication of appendix and cecum: extension of the Cave-Wallbridge classification
    E P Kim
    Department of Surgery, Stanford University Medical Center, Stanford, CA, USA
    J Pediatr Surg 36:E18. 2001
    Duplicated appendix has, to date, been classified into 3 types. The authors present a type of duplicated appendix not previously described. Surgical exploration was done in a 14-year-old girl who had an acute abdomen...
  49. ncbi [Carcinoid tumors of the appendix. A report of 46 cases]
    Mohamed I Beyrouti
    Service de Chirurgie Generale, EPS Habib Bourguiba, Sfax
    Tunis Med 82:668-73. 2004
    Carcinoïd tumors of the appendix are rare. The appendix constitutes the most frequent localization of these tumors...
  50. ncbi Diverticular abscess of the appendix: report of a case and review of the literature
    John Simpson
    Section of Surgery, University Hospital, Nottingham, United Kingdom
    Dis Colon Rectum 46:832-4. 2003
  51. ncbi Schistosomiasis may contribute to goblet cell carcinoid of the appendix
    Yong Jiang
    Department of Pathology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
    J Parasitol 98:565-8. 2012
    Abstract : To investigate whether schistosomiasis can contribute to appendiceal goblet cell carcinoid, appendix samples were obtained from 3 patients with combined appendiceal schistosomiasis and goblet cell carcinoid (CSG), 6 patients ..
  52. ncbi Nonoperative management of pediatric ruptured appendix with inflammatory mass or abscess: presence of an appendicolith predicts recurrent appendicitis
    Sigmund H Ein
    Division of General Surgery, Hospital for Sick Children, Toronto, Ontario, M5G 1X8, Canada
    J Pediatr Surg 40:1612-5. 2005
    The aim of this study was to determine if the presence of an appendicolith is associated with an increased risk for recurrent appendicitis after nonoperative treatment of pediatric ruptured appendix with inflammatory mass or abscess.
  53. ncbi Ovine herpesvirus 2 structural proteins in epithelial cells and M-cells of the appendix in rabbits with malignant catarrhal fever
    Claudia S Meier-Trummer
    Institute of Virology, University of Zurich, Winterthurerstrasse 266a, 8057 Zurich, Switzerland
    Vet Microbiol 137:235-42. 2009
    ..MCF were detected in multiple tissues, those sera detected viral capsid and tegument antigens exclusively in the appendix but not in other tissues of rabbits with MCF...
  54. ncbi Primary epithelial neoplasms and other epithelial lesions of the appendix (excluding carcinoid tumors)
    Joseph Misdraji
    James Homer Wright Pathology Laboratories, Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Semin Diagn Pathol 21:120-33. 2004
    Epithelial tumors of the appendix range from low-grade mucosal-based tumors which, when confined to the appendix, have an excellent prognosis but, once outside the appendix, have a fair prognosis and often a prolonged disease course, to ..
  55. pmc Actinomycosis of the appendix mimicking appendiceal tumor: a case report
    Sang Yun Lee
    Department of Radiology, Dong A University Hospital, Dongdaesindong 3ga, Seo Gu, Pusan 602 715, South Korea
    World J Gastroenterol 16:395-7. 2010
    ..In abdominopelvic actinomycosis, the ileocecal region, including the appendix, is the most commonly involved site...
  56. ncbi Sliding appendiceal inguinal hernia with a congenital fibrovascular band connecting the appendix vermiformis to the right testis
    P Oguzkurt
    Baskent University, Faculty of Medicine, Adana Medical Center, Department of Pediatric Surgery, Turkey
    Hernia 5:156-7. 2001
    It is not uncommon to find the appendix vermiformis within a hernia sac; however, sliding appendiceal inguinal hernia is rare. A 9-month-old boy with an incarcerated right scrotal hernia is presented in this case report...
  57. ncbi [An association of mucocele and carcinoid tumour of the appendix]
    R M Paredes Esteban
    Servicio de Cirugia Pediatrica, Hospital Materno lnfantil, Complejo Hospitalario Ciudad de Jaén, Jaen
    Cir Pediatr 19:250-2. 2006
    The carcinoid tumour of the appendix and the mucocele are entities rather infrequent in children and are normally diagnosed in the course of an appendicectomy that is, in most of the cases, curative...
  58. ncbi US depiction of the appendix: role of abdominal wall thickness and appendiceal location
    Matthew Butler
    Department of Radiology, The Children s Hospital of Philadelphia, 34th and Civic Center Blvd, Philadelphia, PA 19104, USA
    Emerg Radiol 18:525-31. 2011
    ..of abdominal wall fat at the site of exam and appendiceal position with ultrasound (US) visualization of the appendix. The study took place at a large, urban pediatric teaching hospital...
  59. pmc Mucocele of the appendix: an unusual cause of lower abdominal pain in a patient with ulcerative colitis. A case report and review of literature
    Peter Laszlo Lakatos
    1st Department of Medicine, Semmelweis University, Budapest, Hungary
    World J Gastroenterol 11:457-9. 2005
    ..He recovered well and the final histology revealed a cystadenoma of the appendix. Follow up was started. The patient is now free of symptoms...
  60. ncbi [Mucocele of the appendix. Retrospective study of 10 cases]
    M Soueï-Mhiri
    Service de Radiologie, 4064 Sousse, Tunisie
    J Radiol 82:463-8. 2001
    ..The purpose of our work was to assess the value of abdominal sonography (US) and computed tomography (CT) in the preoperative diagnosis of appendiceal mucocele...
  61. ncbi The appendix may protect against Clostridium difficile recurrence
    Gene Y Im
    Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Winthrop University Hospital, Mineola, New York 11501, USA
    Clin Gastroenterol Hepatol 9:1072-7. 2011
    ..Although the function of the appendix has been debated, its active, gut-associated lymphoid tissue and biofilm production indicate potential roles in ..
  62. ncbi Incidental carcinoid of appendix in cesarean section
    Husnu Gokaslan
    Department of Obstetrics and Gynecology, School of Medicine of Marmara University, Istanbul, Turkey
    Eur J Obstet Gynecol Reprod Biol 104:76-8. 2002
    A case with carcinoid tumor of the appendix was encountered incidentally during an elective cesarean section. The tumor was discovered as a result of the routine exploration of the whole abdomen...
  63. ncbi Preoperative diagnostic role of hyperbilirubinaemia as a marker of appendix perforation
    K Atahan
    First Surgical Department, Izmir Ataturk Training and Research Hospital, Izmir, Turkey
    J Int Med Res 39:609-18. 2011
    This retrospective study investigated preoperative markers of appendix perforation in 351 acute appendicitis cases: group 1, appendicitis not histologically confirmed; group 2, appendicitis without perforation or gangrenous changes; and ..
  64. ncbi Fetal cells in the maternal appendix: a marker of inflammation or fetal tissue repair?
    Margarida Avo Santos
    Division of Surgery, Faculty of Medicine, Institute of Reproductive and Developmental Biology, Imperial College London, UK
    Hum Reprod 23:2319-25. 2008
    ..We investigated whether fetal cells participate in maternal tissue repair during human pregnancy...
  65. ncbi [Mucocele of the appendix - a heterogenous surgical pathology]
    M Kleemann
    Universitätsklinikum Schleswig Holstein UK S H, Klinik fur Chirurgie, Lubeck, Deutschland
    Zentralbl Chir 135:330-5. 2010
    Mucoceles of the appendix are rare. After appendectomy, mucoceles are detected with a frequency of 0.2 to 0.3 %...
  66. pmc Residual appendix producing small-bowel obstruction after laparoscopic appendectomy
    R Gordon
    Centre for Minimal Access Surgery, Department of Surgery, St Joseph s Healthcare, McMaster University, Hamilton, Ont
    Can J Surg 47:217-8. 2004
  67. ncbi The use of pedicled appendix graft for substitution of urethra in recurrent urethral stricture
    Satish K Aggarwal
    New Delhi, India
    J Pediatr Surg 37:246-50. 2002
    ..Skin or mucosal grafts, currently used for this purpose, have a high complication rate. The authors describe the use of pedicled appendix for posterior urethral substitution.
  68. ncbi Enterobius vermicularis and clinical appendicitis: worms in the vermiform appendix
    Indra A J Nordstrand
    ANZ J Surg 74:1024-5. 2004
  69. ncbi Villous adenoma of the appendix. Diagnostic and therapeutic approach
    C M Fernández Blanco
    General Surgery Service A, Complexo Hospitalario Juan Canalejo, A Coruna, Spain
    Rev Esp Enferm Dig 94:537-43. 2002
    b>Appendix villous adenoma is a rare pathological entity that shows a particular form of clinical presentation that is different from villous adenomas in other places along the gastrointestinal tract.
  70. ncbi Bifid vermiform appendix: a case report
    Ewen A Griffiths
    Department of General Surgery, Queen Elizabeth Hospital, Gateshead, United Kingdom
    Curr Surg 63:176-8. 2006
    ..009% of appendectomy specimens. The authors report a case of a patient who was found to have 2 appendices at emergency laparotomy, review the classification system used, and discuss the potential clinical pitfalls of similar cases...
  71. ncbi Incidence of visualization of the normal appendix on different MRI sequences
    Paul Nikolaidis
    Department of Radiology, Northwestern University Medical School, 676 North St Clair, Chicago, IL 60611, USA
    Emerg Radiol 12:223-6. 2006
    The purpose of this paper is to assess the incidence of visualization of the normal appendix on magnetic resonance imaging (MRI) examinations of the pelvis in a large adult population and to compare the yield of commonly used sequences...
  72. ncbi Pathology of the appendix in children: an institutional experience and review of the literature
    Raja Rabah
    Department of Pathology, Children s Hospital of Michigan, Wayne State University, 3901 Beaubien St, Detroit, MI 48201 2119, USA
    Pediatr Radiol 37:15-20. 2007
    The appendix can be affected by a variety of congenital and acquired diseases, but acute appendicitis is the most common pathology found in the pediatric population.
  73. ncbi Torsion of the vermiform appendix
    Kapil Gopal
    Section of Pediatric Surgery, Department of Surgery, Temple University Children s Medical Center, Temple University School of Medicine, Philadelphia, PA 19140, USA
    J Pediatr Surg 40:446-7. 2005
  74. ncbi Inverted appendix mistaken for a polyp during colonoscopy and leading to intussusception
    Ashok D Ram
    Department of Paediatric Surgery, Central Manchester and Manchester Children s University Hospitals, UK
    J Cyst Fibros 4:203-4. 2005
    ..However, histopathological examination suggested it was a segment of inverted appendix. The remnant of the inverted appendix was subsequently found to be associated with an intussusception.
  75. ncbi Torsion of the appendix mimicking ovarian torsion
    C Bryce Bowling
    Department of Obstetrics and Gynecology, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Obstet Gynecol 107:466-7. 2006
    ..Appendiceal torsion is rare and generally seen more frequently in children than adults. Untreated it can lead to necrosis, ulceration, and subsequent peritonitis...
  76. ncbi [Torsion of the vermiform appendix associated with intussusception]
    Carlos Baeza-Herrera
    Curso de Cirugía, UNAM, Departamento de Cirugia General, Hospital Pediátrico Moctezuma, Mexico
    Cir Cir 74:369-71. 2006
    BACKGROUND: Vermiform appendix torsion is a rare condition, with only 25 cases recorded in the international literature. Our patient is the first case associated with intussusception...
  77. ncbi Duplex vermiform appendix: case report of a ruptured second appendix
    John R Travis
    Unity Surgical Associates, Fairfax, VA 22030, USA
    J Pediatr Surg 43:1726-8. 2008
    ..Inspection of the cecum revealed a second appendix, which was retrocecal, ruptured, and gangrenous...
  78. ncbi Imaging of acute appendicitis and its impact on negative appendectomy and perforation rates: the St. Paul's experience
    W K Chooi
    Chooi Vally Medical Imaging, Abbotford, BC
    Can Assoc Radiol J 58:220-4. 2007
    ..The aim of this study is to determine the prevalence of preoperative imaging of acute appendicitis in our institution and its effect on the negative appendectomy rate and perforation rates...
  79. ncbi Torsion of the appendix secondary to appendiceal mucocele: gray scale and contrast-enhanced sonographic findings
    Toshihide Hamada
    Department of Gastroenterology, Miyoshi Central Hospital, 531 Higashisakeya, Miyoshi, Hiroshima 728 8502, Japan
    J Ultrasound Med 26:111-5. 2007
  80. ncbi Strangulated appendix within a trocar site incisional hernia following laparoscopic low anterior rectal resection. A case report
    Ch Menenakos
    Department of General, Visceral, Vascular and Thoracic Surgery, Charite Universitaetsmedizin Berlin, Campus Mitte, Berlin, Germany
    Acta Chir Belg 109:411-3. 2009
    b>Appendix strangulation caused by an incisional trocar site hernia following laparoscopy is an extremely rare entity...
  81. ncbi Angiodysplasia of the appendix
    T Kyokane
    Department of Surgery, Yachiyo Hospital, Aichi, Japan
    Am J Gastroenterol 96:242-4. 2001
    ..material from the appendicular artery, and this finding proved to be bleeding from an angiodysplasia of the appendix. An appendectomy was performed, and anal bleeding did not recur postoperatively...
  82. ncbi An "eye" in the gut: the appendix as a sentinel sensory organ of the immune intelligence network
    Kimberly A Bazar
    Department of Dermatology, San Mateo Medical Center, 222 West 39th Avenue, San Mateo, CA 94403, USA
    Med Hypotheses 63:752-8. 2004
    ..We propose that the immune system is a parallel system of intelligence in which the gut, including the appendix, plays a prominent role in data acquisition...
  83. ncbi Localization of the appendix at MR imaging during pregnancy: utility of the cecal tilt angle
    Karen S Lee
    Department of Radiology, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215, USA
    Radiology 249:134-41. 2008
    ..whether the cecal tilt angle on sagittal magnetic resonance (MR) images in pregnant patients correlates with the location of the appendix and gestational age and whether the cecal tilt angle can help predict the location of the appendix.
  84. ncbi Endometriosis at several sites, cyclic bowel symptoms, and the likelihood of the appendix being affected
    Mauricio Simoes Abrao
    Department of Obstetrics and Gynecology, University of Sao Paulo Medical School, Sirio Libanes Hospital, Sao Paulo, Brazil
    Fertil Steril 94:1099-101. 2010
    In patients with endometriosis of the appendix, other sites are use to be affected by the disease, mainly bladder, rectosigmoid and retrocervical endometriosis...
  85. ncbi Appendicitis and infections of the appendix
    Laura W Lamps
    Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
    Semin Diagn Pathol 21:86-97. 2004
    The pathologic spectrum of the acutely inflamed appendix encompasses a wide range of infectious and noninfectious entities...
  86. pmc Endometriosis of the appendix
    Nasser S Al Oulaqi
    Department of Surgery, Al Ain Hospital, Al Ain, United Arab Emirates
    Afr Health Sci 8:196-8. 2008
    Endometriosis is a well known cause of infertility. Endometriosis of the appendix is a very rare condition...
  87. ncbi US examination of the appendix in children with suspected appendicitis: the additional value of secondary signs
    Fraukje Wiersma
    Department of Radiology, Haga Teaching Hospital, Location Leyweg, Leyweg 275, 2545 CH The Hague, The Netherlands
    Eur Radiol 19:455-61. 2009
    ..Ultrasonographic depiction of the appendix was classified into four groups: 1, normal appendix; 2, appendix not depicted, no secondary signs of appendicitis;..
  88. ncbi Laparoscopic appendectomy for mucocele of the appendix: Report of 8 cases
    Muthukumaran Rangarajan
    GEM Hospital, 45 A Pankaja Mill Road, Ramnathapuram, Coimbatore 641 045, India
    Indian J Gastroenterol 25:256-7. 2006
    Mucocele of the appendix is an aseptic dilatation secondary to obstruction. Surgical excision is the treatment of choice in benign mucocele. The incidence of mucocele of the appendix in our center is 0...
  89. ncbi Suspected acute appendicitis in female patients. Trends in diagnosis in emergency department in a University Hospital in Western region of Saudi Arabia
    Fatma K Althoubaity
    Department of Surgery, King Abdul Aziz University Hospital, PO Box 80215, Jeddah 21589, Kingdom of Saudi Arabia
    Saudi Med J 27:1667-73. 2006
    ..To determine the negative appendectomy rate; utilization, accuracy of Alvarado scale, ultrasound (US), computed tomography (CT) in diagnosis of acute appendicitis...
  90. ncbi Bullet fragment within the appendix: a case report
    Thomas V Mincheff
    Hartsville Surgical Center 704 Medical Park Drive, Hartsville, SC 29550, USA
    J S C Med Assoc 100:270-3. 2004
    ..other diagnostic tests, which ultimately revealed and verified that the metal fragment was lodged in the distal appendix. Careful family history obtained showed that the family eats a great deal of wild game, including deer meat...
  91. ncbi Retroperitoneal perforation of the appendix presenting as right thigh abscess
    Nabil S El-Masry
    Department of Surgery, Charing Cross Hospital, London, United Kingdom
    Int Surg 87:61-4. 2002
    A case of retroperitoneal perforation of the appendix presenting with a thigh abscess is described. The patient presented with pyrexia (38 degrees C) and abdominal and right thigh pain. There was tenderness in the right loin...
  92. ncbi The primary site of CD4- 8- B220+ alphabeta T cells in lpr mice: the appendix in normal mice
    S Yamagiwa
    Department of Immunology, Niigata University School of Medicine, Japan
    J Immunol 160:2665-74. 1998
    ..We herein report, however, that such alphabeta T cells were abundant at intraepithelial sites of the appendix in normal mice. They lacked the expression of NK1...
  93. ncbi Torsion of the vermiform appendix: a case report
    T J R Bestman
    Department of Surgery, O L V Middelares Hospital Deurne, Antwerp, Belgium
    Acta Chir Belg 106:228-9. 2006
    This case report describes a rare condition, namely a torsion of the vermiform appendix. Its clinical condition is indistinguishable from acute appendicitis.
  94. ncbi CT appearance of the normal appendix in adults
    Stefania Tamburrini
    Dip Sc Biomorfologiche e Funzionali, Universita di Napoli Federico II, IBB CNR, Via Pansini 5, 80131, Naples, Italy
    Eur Radiol 15:2096-103. 2005
    The aims of this study were to identify (1) the normal range of the appendix on computed tomography (CT), (2) the correlation of patient age and sex with the visibility and appearance of the appendix on CT, and (3) the normal variations ..
  95. ncbi Three-dimensional and ultrastructural aspects of the lymphatic vascularization of the vermiform appendix
    G Azzali
    Institute of Human Anatomy, Faculty of Medicine, University of Parma, Italy
    J Submicrosc Cytol Pathol 30:545-53. 1998
    ..three-dimensional distribution and ultrastructure of the peripheral absorbing lymphatic vessels of the vermiform appendix, since the gut-associated lymphoid tissue is necessary to the immune responses to the enteric antigens...
  96. ncbi Torsion of an epiploic appendix mimicking acute appendicitis
    Hisham S Hurreiz
    Department of Surgery, Newham General Hospital, Glen Road, Plaistow, London, United Kingdom
    Saudi Med J 26:2003-4. 2005
  97. ncbi CD5+ B cells are preferentially expanded in rabbit appendix: the role of CD5 in B cell development and selection
    Richard Pospisil
    Laboratory of Immunology, NIAID, National Institutes of Health, Bethesda, MD 20892 1892, USA
    Dev Comp Immunol 30:711-22. 2006
    ..However, CD5 was not detectable on the majority of B cells in neonatal appendix 1 and 3days after birth...
  98. ncbi Needle perforation of the appendix
    K Renner
    Department of Surgery, Danube Hospital SMZ Ost, Vienna, Austria
    Dig Surg 17:413-4. 2000
    ..Needles are among the most frequently swallowed foreign bodies. In most cases they are excreted per vias naturales, but in some cases needles can lead to perforation of the stomach or duodenum in adults...
  99. pmc Activation-induced deaminase cloning, localization, and protein extraction from young VH-mutant rabbit appendix
    Guibin Yang
    Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, and SAIC Frederick, National Cancer Institute, Frederick, MD 21701, USA
    Proc Natl Acad Sci U S A 102:17083-8. 2005
    ..Developing rabbit appendix provides a particularly good site for studying all three of these B cell maturation events...
  100. ncbi Bacterial-induced inflammation in germ-free rabbit appendix
    Malathy Shanmugam
    Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University of Chicago, Maywood, Illinois 60153, USA
    Inflamm Bowel Dis 11:992-6. 2005
    ..In this report, we document the use of a germ-free ligated rabbit appendix model to induce inflammatory changes in response to specific bacteria...
  101. ncbi Comparative assessment of CT and sonographic techniques for appendiceal imaging
    S W Wise
    Department of Radiology, Pennsylvania State University College of Medicine, Milton S. Hershey Medical Center, 500 University Dr, Hershey, PA 17033, USA
    AJR Am J Roentgenol 176:933-41. 2001
    ..However, focused appendiceal CT with colonic contrast material material should be used as a problem-solving technique in difficult cases...

Research Grants73

  1. Role of the kallikrein-kinin system in diabetic retinopathy
    Edward P Feener; Fiscal Year: 2012
    ..Nature Medicine 2007, Appendix 1)...
  2. PTEN TUMOR SUPPRESSOR AND SIGNAL TRANSDUCTION
    RAMON E PARSONS; Fiscal Year: 2012
    ..g., Consultants) 52-53 Commercialization Plan (SBIR/STTR Phase II and Fast-Track ONLY) Checklist. 54. Appendix (Five collated sets. No page numbering necessary for Appendix...
  3. VISUAL SCIENCES TRAINING PROGRAM
    Eric Pearlman; Fiscal Year: 2013
    ..Data Tables 15. Letters of Support Checklist Appendix (Five identical CDs.) N/A [unreadable]\ 21 23 23 . (Items 2-5: not to exceed 25 pages, 26 ....
  4. Developing Physics-Based Virtual Simulation Technology for Natural Orifice Transl
    DANIEL BOUGERE JONES; Fiscal Year: 2013
    ..models and experimental data generated in SA1 and develop the prototype of a virtual NOTES appendectomy (appendix removal) simulator which incorporates physiological consequence of surgical complications and allows comparison ..
  5. Lung VITamin D and OmegA-3 TriaL (Lung VITAL)
    Diane R Gold; Fiscal Year: 2013
    ..that this ancillary study be undertaken in parallel to the enrollment period for the parent VITAL trial (Appendix B), which is scheduled to begin in January 2010...
  6. Targeting Galectin-1 with radiation in lung cancer
    QUYNH THU XUAN LE; Fiscal Year: 2013
    ..Gal-1 is more important than host- derived Gal-1 in promoting tumor growth and spontaneous metastasis (Appendix 3)...
  7. Regional Biocontainment Laboratory
    Charles Bailey; Fiscal Year: 2007
    ..Applicant-Provided Matching Funds (Form 424, item 15b) GMU has completed a Teaming Agreement with TRex Capital (Appendix 1) and received a Letter of Intent from TRex Capital (Appendix 2) which states that, should GMU be awarded $25 ..
  8. Regulation of Organized Intestinal Lymphoid Tissues by TRANCE/RANKL
    Ifor R Williams; Fiscal Year: 2012
    ..While M cells were first described in the rabbit appendix over 30 years ago and are known to have a central role in uptake of particulate antigens in mucosal tissues while ..
  9. EFFECT OF R1R2 OVER-EXPRESSION ON CARDIAC FUNCTION
    Michael Regnier; Fiscal Year: 2013
    ..In a recent paper (2011, JMCC. 51:894-901;Appendix 1), we demonstrated that increasing [dATP] in cultured adult rat cardiomyocytes by over-expression of R1R2 ..
  10. Serotonergic Immunomodulation in Neuroinflammatory Disease
    CATHERINE ELIZABETH HAGAN; Fiscal Year: 2012
    ..Literature Cited...! 86-90 I. Consortium/Contractual Arrangements* n/a J. Resource Sharing n/a Checklist 91 Appendix (Five collated sets. No page numbering necessary...
  11. CRTC2 in Cellular Development, Function, and Neoplasia
    Michael A Teitell; Fiscal Year: 2013
    ..self-renewal, and differentiation into antibody (Ab)-secreting plasma cells while opposing lymphomagenesis (see Appendix- Sherman, et al., Molecular Cell, in press, 2010)...
  12. A3AR agonists to prevent chemotherapy-induced painful peripheral neuropathy
    Daniela Salvemini; Fiscal Year: 2013
    ..A3 adenosine receptor (A3AR) agonism as a new viable therapeutic strategy for treating or reversing CIPN (Appendix 1 &ref8)...
  13. 15th International Workshop on Ataxia-Telangiectasia and ATM to be held in India
    Tej K Pandita; Fiscal Year: 2012
    ..short visit to Delhi, we looked at several very acceptable sites with which each of you would be quite pleased (Appendix 1)"...
  14. Intratumoral genetic therapy for lung cancer
    Steven M Dubinett; Fiscal Year: 2013
    ..venules in lymph nodes and Peyer's patches and by lymphatic vessels, stromal cells in the spleen and appendix. CCL21 binds to the chemokine receptor CCR7 and is chemoattractant for mature DCs, naive and memory T cells...
  15. An Investigation of the Clinical Utility of a Prolonged Grief Disorder Diagnosis
    Holly Gwen Prigerson; Fiscal Year: 2013
    ..In DSM-5, it is proposed as a new subtype of Adjustment Disorder and included in the "Appendix for Further Study...
  16. Patient Awareness and Consumer Education Research Cente*
    Maria E Suarez Almazor; Fiscal Year: 2010
    ..Checklist 171 Appendix (Five collatedsets. Nopage numbering necessary forAppendix...
  17. Study of Women's Health Across the NationIV: Chicago Site
    Howard M Kravitz; Fiscal Year: 2013
    ..The SWAN PI and study coordinator were subsequently exonerated from these allegations. Please see Appendix 12 for a more complete report. The grant was transferred to the Albert Einstein College of Medicine in 2005...
  18. Molecular and Cellular Basis of Oncogene Addiction
    Dean W Felsher; Fiscal Year: 2010
    ..inactivation, there are specific and sustained changes in gene expression [Wu et al, PLoS Genetics [1];and see Appendix, Shachaf et al, Cancer Research, 2008]...
  19. Stress Impaired Microbial Clearance
    Phillip T Marucha; Fiscal Year: 2012
    ..1998;Kiecolt-Glaser, Marucha et al. 1995, see appendix)...
  20. Manganese Superoxide Dismutase and Renal Ischemia/Reperfusion
    LEE A MACMILLAN-CROW; Fiscal Year: 2013
    ..24 hr) pretreatment of rats with MnP significantly improved MnSOD activity and renal function during I/R (Appendix 2)...
  21. AP1-dependent regulation of bone mass and energy expenditure in the hypothalamus
    ROLAND E BARON; Fiscal Year: 2013
    ..2009) and one being prepared for submission (see Appendix ASBMR Abstract, 2009), have generated some very exciting new data which in our view deserve further investigation ..
  22. Genetic dissection of parasite metabolism
    Boris Striepen; Fiscal Year: 2013
    ..to cause significant waterborne outbreaks and has been listed by the CDC as a potential bioterrorism pathogen (appendix B)...
  23. The Role of IL-10 in Regulation of Allergic Inflammation
    BILL AMEREDES; Fiscal Year: 2009
    ..b>Appendix (Five collated sets. No page numbering necessary for Appendix...
  24. Manipulating b1 integrin to enhance radiation therapy for breast cancer
    Catherine C Park; Fiscal Year: 2012
    ..global consequences of IR on the normal tissue microenvironment can also have important clinical implications (Appendix I)...
  25. IMPROVING ANIMAL RESOURCES FOR BIOMEDICAL RESEARCH
    Sylvia Kondo; Fiscal Year: 2009
    ..Check if Appendix (Five collatedsets. Nopage numbering necessary for Appendix...
  26. NEUROPHARMACOLOGY OF ETHANOL REINFORCEMENT
    Olivier George; Fiscal Year: 2013
    ..within the brain emotional systems normally used to maintain emotional homeostasis (Koob and Le Moal, 2005, 2008, Appendix) and produce compulsive drinking via negative reinforcement mechanisms...
  27. Neurodegeneration in Aged SIV-Infected Primates
    Clayton A Wiley; Fiscal Year: 2013
    ..of chronic HIV infection and our recent studies of neuroinflammation in aged NHPs (Kofler et al 2011 (41) see appendix), we will test our overarching hypothesis that: chronic systemic CART with or without chronic lentiviral ..
  28. Internet-Based Smoking Cessation for OEF/OIF Veterans
    Patrick S Calhoun; Fiscal Year: 2013
    ..Limited detail about nicotine replacement protocol is now provided as an Appendix. g. Data analysis plan: Very well written. Power now better addressed but Table 4 was missing. h...
  29. Genetic dissection of parasite metabolism
    Boris Striepen; Fiscal Year: 2009
    ..to cause significant waterborne outbreaks and has been listed by the CDC as a potential bioterrorism pathogen (appendix B)...
  30. SWAN: Study of Women's Health Across the Nation
    Joel S Finkelstein; Fiscal Year: 2013
    ..The SWAN PI and study coordinator were subsequently exonerated from these allegations. Please see Appendix 12 for a more complete report. The grant was transferred to the Albert Einstein College of Medicine in 2005...
  31. Study of Women's Health Across the Nation IV: UCLA Site
    Gail A Greendale; Fiscal Year: 2013
    ..The SWAN PI and study coordinator were subsequently exonerated from these allegations. Please see Appendix 12 for a more complete report. The grant was transferred to the Albert Einstein College of Medicine in 2005...
  32. Role of Polo-Like Kinase-1 in Melanocytic Transformation
    Nihal Ahmad; Fiscal Year: 2013
    ..In a recent study (J Invest Dermatol, In Press;Appendix-1), we have found that, i) Plk1 was over-expressed in both clinical tissue specimens and cultured human melanoma ..
  33. Enhanced Surveillance for New Vaccine Preventable Diseases
    Rangaraj Selvarangan; Fiscal Year: 2013
    ..a high burden of HPeV3-CNS infections (18%) in US children during 2007 and 2009 (Selvarangan et al 2010;appendix 3)...
  34. The Population Genetics of Divergence
    EMANUEL HEY; Fiscal Year: 2013
    ..Resource Sharing na L. Letters of Support (e.g., Consultants) na Checklist. 47 Check if Appendix(Fivecollatedsets.NopagenumberingnecessaryforAppendix...
  35. Fourth Dense Deposit Disease Focus Group Meeting
    Richard J H Smith; Fiscal Year: 2011
    ..2005;Smith et al., 2007) and have impacted the care of patients with DDD (see Appendix)...
  36. Preclinical Consortium to Facilitate Translation of Cardioprotective Therapies
    Roberto Bolli; Fiscal Year: 2013
    ..The need for this infrastructure is attested to by 30 letters (Appendix). This will be a paradigm shift in cardioprotection...
  37. Nucleotide Regulation of Apaf-1 Apoptosome and Apoptosis
    Dean G Tang; Fiscal Year: 2010
    ..Cell 125, 1333-1346, 2006;Appendix I). Consequently, the CC- mediated apoptosome assembly and activation are blocked...
  38. OTHER FUNCTIONS TAS::75 0849::TAS AGRICULTURAL HEALTH STUDY PHASE IV--MOD 3:
    Marsha Dunn; Fiscal Year: 2012
    ..New responsibilities under this contract will be the conduct of the Biomarker Study (BEEA: protocol attached in appendix) which will involve the collection of blood and urine samples from a subset of the cohort.
  39. OTHER FUNCTIONS TAS::75 0849::TAS AGRICULTURAL HEALTH STUDY PHASE IV--MOD 3:
    Marsha Dunn; Fiscal Year: 2013
    ..New responsibilities under this contract will be the conduct of the Biomarker Study (BEEA: protocol attached in appendix) which will involve the collection of blood and urine samples from a subset of the cohort.
  40. The Incidence and Etiology of Influenza-Associated Pneumonia in Hospitalized Pers
    KATHRYN MARGARET EDWARDS; Fiscal Year: 2010
    ..audits will be performed by the VUMC-VVRP quality assurance manager and the performance plan is included in the appendix of this application...
  41. Morehouse Sch of Medicine/Tuskegee Univ/University of Alabama Ca Ctr Partnership
    Timothy Turner; Fiscal Year: 2013
    ..this Partnership have published 75 peer-reviewed manuscripts that are directly related to cancer disparities (see Appendix A-C)...
  42. Xylitol Adult Caries Trial (X-ACT): UAB Clinical Center
    Gregg H Gilbert; Fiscal Year: 2010
    ..A Manual of Procedures appears as an appendix to this Study Chair application. Relevance to public health: Tooth decay is a serious problem for many adults...
  43. Xylitol Adult Caries Trial (X-ACT)--UNC Clinical Center
    Daniel A Shugars; Fiscal Year: 2010
    ..A Manual of Procedures appears as an appendix to this Study Chair application. Relevance to public health: Tooth decay is a serious problem for many adults...
  44. Acquisition of a Carl Zeiss Cell Observer Spinning Disk Confocal Microscope
    J Michael McCaffery; Fiscal Year: 2013
    ..School of Arts and Sciences and the Whiting School of Engineering (see Ball &Douglas letter, page 2 of the appendix);and utilized regularly by multiple schools and departments comprising >100 laboratories and >300 users...
  45. Xylitol Adult Caries Trial (X-ACT) UTHSC San Antonio Clinical Center
    Bennett Tochukwu Amaechi; Fiscal Year: 2010
    ..A Manual of Procedures appears as an appendix to this Study Chair application. Relevance to public health: Tooth decay is a serious problem for many adults...
  46. Xylitol Adult Caries Trial (X-ACT) Data Coordinating Center
    WILLIAM MARION VOLLMER; Fiscal Year: 2011
    ..A Manual of Procedures appears as an appendix to this Study Chair application. Relevance to public health: Tooth decay is a serious problem for many adults...
  47. Xylitol Adult Caries Trial (X-ACT)--Study Chair application
    James D Bader; Fiscal Year: 2010
    ..A Manual of Procedures appears as an appendix to this Study Chair application. Relevance to public health: Tooth decay is a serious problem for many adults...
  48. Biopolymer Surfactants for Sealing Electroporated Membranes
    RAPHAEL CARL LEE; Fiscal Year: 2010
    ..b>Appendix A)...
  49. Genomics Resources and Infrastucture for the Zebrafish
    Chris T Amemiya; Fiscal Year: 2012
    ..articulated in a communal White Paper to NIH, "Zebrafish as a model system to study and cure human disease" (see Appendix)...
  50. Trauma Molecular Pathogenesis and Regeneration Training Grant
    RAPHAEL CARL LEE; Fiscal Year: 2013
    ..molecular pathogenesis and treatment of injury and is the outgrowth of well-established formal graduate courses(Appendix I-3) and research programs in tissue injury and repair at the University of Chicago...
  51. Stress-activated signaling in prostate cancer
    GEORGE A KULIK; Fiscal Year: 2012
    ..phosphorylation of the pro-apoptotic protein BAD and protects prostate cancer cells from apoptosis (JBC2007 in "appendix")...
  52. Naloxone Nasal Spray Development
    DANIEL PAUL WERMELING; Fiscal Year: 2013
    ..extensive negotiations with the Food and Drug Administration (FDA) regarding the development path for NLX NS (see Appendix)...
  53. Quantization of Ocular Oxygen using a Modified Fluorotron
    James P Dillon; Fiscal Year: 2010
    ..will be compared to those obtained using an optode, which is a method that we have successfully used before (see appendix 2). III) After a vitrectomy the vitreous is replaced by various solutions that are at atmospheric oxygen...
  54. Clinical algorithm for identifying adult autism
    David S Mandell; Fiscal Year: 2013
    ..disorders in prior studies (developmental history, neurological problems, substance use and criminal activity~ Appendix B)~ 2) structured clinical interviews using the Autism Diagnostic Observation Schedule, Module 4, and the ..
  55. Cholesterol and Sphingolipid Metabolism in Alzheimer's Disease
    Ta Yuan Chang; Fiscal Year: 2013
    ..In a new manuscript (included in the Appendix) and in the PRELIMINARY STUDIES section, we describe the following leads: 1...
  56. Neurocircuitry Mapping and Genotyping Core
    Robert J Hitzemann; Fiscal Year: 2013
    ..2010) and b) the development of a strategy for and implementation of quantitative RNAseq (Bottomly et al, 2011;Appendix A)...
  57. Friends Helping Friends: Socially Responsible ATOD Prevention
    Constance A Flanagan; Fiscal Year: 2010
    ..to dissuade friends from ATOD use (funded by NIDA: RO1 DA13434;see Flanagan, Elek-Fisk, &Gallay, 2004 in Appendix F)...
  58. AR CAREER DEVELOPMENT COBRE: ADMINISTRATIVE CORE
    Edgar E Garcia-Rill; Fiscal Year: 2011
    ..This self-assessment tool is included in Appendix #4 and was developed by the University of Pittsburgh...
  59. Designing for Patient Safety: Developing methods to integrate patient safety conc
    Anjali Joseph; Fiscal Year: 2011
    ..Brief introductory language around a 'patient safety risk assessment'(PSRA) has been included in the appendix of the 2010 Guidelines for Design and Construction of Healthcare Facilities (a key information resource and ..
  60. Ninth International Congress on Toxoplasmosis
    Boris Striepen; Fiscal Year: 2007
    ..S. is complicated by toxoplasmosis. T. gondii[unreadable] is also considered a potential bioterrorism threat (appendix B) due to its ability to cause[unreadable] waterborne outbreaks. Lastly, T...
  61. CONTROL OF CORNEAL ENDOTHELIUM DEVELOPMENT IN THE MOUSE
    Christopher Wright; Fiscal Year: 2002
    ..of anterior chamber formation, iris dystrophy, and abnormalities of the trabecular meshwork (Kidson et al, 1999, Appendix)...
  62. Evolving Inproved Formate Dehydrogenases
    JAMES ROZZELL; Fiscal Year: 2005
    ..With the increased availability of various oxidoreductases (BioCatalytics, Inc. 2003 catalog, see appendix), and the work on existing processes using amino acid dehydrogenases and alcohol dehydrogenases to make non-..
  63. SHORT COURSE AND CERTIFICATE PROGRAM IN RESEARCH ETHICS
    Albert Jonsen; Fiscal Year: 2000
    ..These participant evaluation tools can be found in the Appendix. 51/55 participants completed the pre course evaluation; 39/55 participants completed the post course evaluation...
  64. FAS AND BC1-2 AND GRANULOSA CELL APOPTOSIS
    Nicholas Cataldo; Fiscal Year: 2000
    ..He has published five first-author papers, and another has been submitted (Appendix). Research plan...
  65. 2ND INTERNAT'L SYMPOSIUM OF VERTEBRATE SEX DETERMINATION
    Valentine Lance; Fiscal Year: 2000
    ..There was an overwhelmingly positive response to holding a second meeting in three years (see appendix)...
  66. Domoic Acid and Neonatal Microglia Activation
    Alejandro Mayer; Fiscal Year: 2004
    ..Our working hypothesis, which we have published ((58) and Appendix # 2), is that ".....
  67. DIAGNOSTIC CENTER
    M Lucia; Fiscal Year: 2004
    ..Blood chemistries will be carried out initially and annually for the duration of the trial (described in Appendix F of the protocol)...
  68. PATHOGENIC CONVERSION OF ATTENUATED SIV VACCINES
    Earl Sawai; Fiscal Year: 2003
    ..1999-Appendix) These findings indicate strong selection pressure to restore pathogenic potential in live attenuated primate ..
  69. WORK AND BLOOD LEAD RELATIONSHIPS AMONG BRIDGE WORKERS
    S Hammond; Fiscal Year: 2000
    ..Vork et. al., submitted) (Appendix A)...
  70. Pathobiology of HMG-CoA reductase inhibitors in diabetes
    Yashpal Kanwar; Fiscal Year: 2006
    ..al., ref. # 18, appendix # 1)...