gallbladder

Summary

Summary: A storage reservoir for BILE secretion. Gallbladder allows the delivery of bile acids at a high concentration and in a controlled manner, via the CYSTIC DUCT to the DUODENUM, for degradation of dietary lipid.

Top Publications

  1. ncbi Proton pump inhibitors reduce gallbladder function
    M A Cahan
    Department of Surgery, University of North Carolina at Chapel Hill, Campus Box 7081, Chapel Hill, North Carolina 27599 7081, USA
    Surg Endosc 20:1364-7. 2006
  2. doi Prostate stem cell antigen, a presumable organ-dependent tumor suppressor gene, is down-regulated in gallbladder carcinogenesis
    Hiroe Ono
    Division of Genetics, National Cancer Center Research Institute, Tokyo, Japan
    Genes Chromosomes Cancer 51:30-41. 2012
  3. ncbi Activation of liver X receptor sensitizes mice to gallbladder cholesterol crystallization
    Hirdesh Uppal
    Center for Pharmacogenetics, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Hepatology 47:1331-42. 2008
  4. ncbi Hepatic Helicobacter species identified in bile and gallbladder tissue from Chileans with chronic cholecystitis
    J G Fox
    Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 4307, USA
    Gastroenterology 114:755-63. 1998
  5. ncbi Hypermethylation of the Ras association domain family 1A (RASSF1A) gene in gallbladder cancer
    Se Kook Kee
    Department of Anatomy, Kyungpook National University, Daegu 702 422, Korea
    Mol Cells 24:364-71. 2007
  6. ncbi Gallstone disease
    H U Marschall
    Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm, Sweden
    J Intern Med 261:529-42. 2007
  7. doi Coordinate regulation of gallbladder motor function in the gut-liver axis
    Piero Portincasa
    Department of Internal Medicine and Public Medicine, Clinica Medica A Murri, University of Bari Medical School, Bari, Italy
    Hepatology 47:2112-26. 2008
  8. ncbi The human gallbladder secretes fibroblast growth factor 19 into bile: towards defining the role of fibroblast growth factor 19 in the enterobiliary tract
    Serge J L B Zweers
    Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam, The Netherlands
    Hepatology 55:575-83. 2012
  9. ncbi Identification of a hormonal basis for gallbladder filling
    Mihwa Choi
    Department of Molecular Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390, USA
    Nat Med 12:1253-5. 2006
  10. pmc Estrogen-dependent gallbladder carcinogenesis in LXRbeta-/- female mice
    Chiara Gabbi
    Department of Biosciences and Nutrition, Karolinska Institutet, S 141 86 Novum, Sweden
    Proc Natl Acad Sci U S A 107:14763-8. 2010

Detail Information

Publications259 found, 100 shown here

  1. ncbi Proton pump inhibitors reduce gallbladder function
    M A Cahan
    Department of Surgery, University of North Carolina at Chapel Hill, Campus Box 7081, Chapel Hill, North Carolina 27599 7081, USA
    Surg Endosc 20:1364-7. 2006
    In the authors' previous study of gallbladder function before and after fundoplication, 58% of the patients demonstrated preoperative gallbladder motor dysfunction, and 86% of those retested after operation and cessation of proton pump ..
  2. doi Prostate stem cell antigen, a presumable organ-dependent tumor suppressor gene, is down-regulated in gallbladder carcinogenesis
    Hiroe Ono
    Division of Genetics, National Cancer Center Research Institute, Tokyo, Japan
    Genes Chromosomes Cancer 51:30-41. 2012
    b>Gallbladder cancer (GBC) is relatively rare but has a high mortality rate...
  3. ncbi Activation of liver X receptor sensitizes mice to gallbladder cholesterol crystallization
    Hirdesh Uppal
    Center for Pharmacogenetics, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Hepatology 47:1331-42. 2008
    Gallstone disease is a hepatobiliary disorder due to biochemical imbalances in the gallbladder bile...
  4. ncbi Hepatic Helicobacter species identified in bile and gallbladder tissue from Chileans with chronic cholecystitis
    J G Fox
    Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 4307, USA
    Gastroenterology 114:755-63. 1998
    Cancer of the gallbladder is the number one cause of cancer mortality in Chilean women...
  5. ncbi Hypermethylation of the Ras association domain family 1A (RASSF1A) gene in gallbladder cancer
    Se Kook Kee
    Department of Anatomy, Kyungpook National University, Daegu 702 422, Korea
    Mol Cells 24:364-71. 2007
    ..the expression of RASSF1A protein, and the correlation between these and the clinicopathological features of gallbladder (GB) cancer in Korean patients...
  6. ncbi Gallstone disease
    H U Marschall
    Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm, Sweden
    J Intern Med 261:529-42. 2007
    ..This review summarizes current concepts on the pathogenesis of cholesterol gallstones with focus on the uptake and secretion of biliary lipids and special emphasis on recent studies into the genetic background...
  7. doi Coordinate regulation of gallbladder motor function in the gut-liver axis
    Piero Portincasa
    Department of Internal Medicine and Public Medicine, Clinica Medica A Murri, University of Bari Medical School, Bari, Italy
    Hepatology 47:2112-26. 2008
    ..In cholesterol gallstone disease, the gallbladder becomes the target organ of a complex metabolic disease...
  8. ncbi The human gallbladder secretes fibroblast growth factor 19 into bile: towards defining the role of fibroblast growth factor 19 in the enterobiliary tract
    Serge J L B Zweers
    Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam, The Netherlands
    Hepatology 55:575-83. 2012
    ..FGF19 messenger RNA was found to be abundantly expressed in the human gallbladder and in the common bile duct, with only minor expression observed in the ileum...
  9. ncbi Identification of a hormonal basis for gallbladder filling
    Mihwa Choi
    Department of Molecular Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390, USA
    Nat Med 12:1253-5. 2006
    The cycle of gallbladder filling and emptying controls the flow of bile into the intestine for digestion...
  10. pmc Estrogen-dependent gallbladder carcinogenesis in LXRbeta-/- female mice
    Chiara Gabbi
    Department of Biosciences and Nutrition, Karolinska Institutet, S 141 86 Novum, Sweden
    Proc Natl Acad Sci U S A 107:14763-8. 2010
    b>Gallbladder cancer is a highly aggressive disease with poor prognosis that is two to six times more frequent in women than men...
  11. ncbi Cystogastrocolic fold and associated atrophy of the gallbladder
    N Pamidi
    Department of Anatomy, Melaka Manipal Medical College, Manipal University, Manipal 576104, Karnataka, India
    Singapore Med J 49:e250-1. 2008
    ..We report the presence of a cystogastrocolic fold associated with an abnormally small gallbladder in a 50-year-old male cadaver...
  12. ncbi Ultrastructure of Myxidium trachinorum sp. nov. from the gallbladder of the lesser weever fish Echiichthys vipera
    E U Canning
    Department of Biology, Imperial College of Science, Technology and Medicine, London, UK
    Parasitol Res 85:910-9. 1999
    Myxidium trachinorum sp. nov. is described from the gallbladder of the lesser weever fish Echiichthys vipera. Pseudoplasmodia attach themselves to the gallbladder epithelium by filose processes, which are inserted between host cells...
  13. ncbi Comparison of artificial neural networks with logistic regression in prediction of gallbladder disease among obese patients
    P L Liew
    Department of Pathology, En Chu Kong Hospital, Taipei Hsien, Taiwan
    Dig Liver Dis 39:356-62. 2007
    Obesity is a risk factor for gallbladder disease. The authors retrospectively analyse the prevalence and risk factors of gallbladder disease using logistic regression and artificial neural networks among obese patients in Taiwan.
  14. doi Endoscopic gallbladder drainage for management of acute cholecystitis
    Takao Itoi
    Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan
    Gastrointest Endosc 71:1038-45. 2010
    Nonoperative gallbladder drainage methods for acute cholecystitis include percutaneous transhepatic gallbladder drainage and percutaneous transhepatic gallbladder aspiration, endoscopic nasogallbladder drainage and gallbladder stenting ..
  15. ncbi Significance of extensive surgery including resection of the pancreas head for the treatment of gallbladder cancer--from the perspective of mode of lymph node involvement and surgical outcome
    Ryoko Sasaki
    Department of Surgery I, Iwate Medical University, 19 1 Uchimaru, Morioka, 020 8505, Japan
    World J Surg 30:36-42. 2006
    ..of extensive surgery, including pancreas head resection, for more complete lymphadenectomy in the treatment of gallbladder carcinoma...
  16. ncbi E-cadherin and beta-catenin expression in normal, inflamed and cancerous gallbladder tissue
    Harald Puhalla
    Department of General Surgery, General Hospital, Medical University of Vienna, 1090 Vienna, Austria
    Anticancer Res 25:4249-54. 2005
    ..b>Gallbladder carcinoma (GBC) can develop during chronic inflammation from normal tissue...
  17. ncbi Enteroscopic cyanoacrylate sclerotherapy of jejunal and gallbladder varices in a patient with portal hypertension
    S Getzlaff
    Dept. of Gastroenterology, City Hospital, Ludwigshafen am Rhein (University of Mainz Medical School, Germany
    Endoscopy 33:462-4. 2001
    ..We present here a report on the diagnosis and treatment of bleeding jejunal and gallbladder varices in a man with portal hypertension caused by chronic calcifying pancreatitis...
  18. ncbi [Precancerous lesions of the gallbladder]
    R Kianmanesh
    Service de Chirurgie Generale et Digestive, Hôpital Louis Mourier AP HP, Université Paris VII Colombes
    J Chir (Paris) 144:278-86. 2007
    ..Mini-review summarizes the epidemiology, predisposing and pre-cancerous conditions related to carcinoma of the gallbladder. In 75% of cases, gallbladder cancer is a cholangiocarcinoma, usually presenting in a late and advanced stage, ..
  19. ncbi Molecular cloning and functional expression of the human gallbladder cholecystokinin A receptor
    C D Ulrich
    Center for Basic Research in Digestive Diseases, Mayo Clinic, Rochester, MN 55905
    Biochem Biophys Res Commun 193:204-11. 1993
    Through binding to cholecystokinin (CCK) A receptors, CCK is an important physiologic regulator of both gallbladder contraction and pancreatic enzyme secretion...
  20. pmc Renal cell carcinoma with metastases to the gallbladder: four cases from the National Cancer Institute (NCI) and review of the literature
    Paul H Chung
    Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Urol Oncol 30:476-81. 2012
    We evaluate presentation and outcome of patients with metastatic RCC to the gallbladder from our institution and published literature.
  21. ncbi MUC 1 core protein as a marker of gallbladder malignancy
    M Ghosh
    Department of Gastroenterological and Hepatobiliary Surgery, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba Shi 305, Japan
    Eur J Surg Oncol 31:891-6. 2005
    The significance of MUC 1 expression in the gallbladder tissues in relation to cancer and non-cancer disease is not well understood. The aim of this study was to clarify the significance of MUC 1 expression.
  22. doi New species of Myxosporea from frogs and resurrection of the genus Cystodiscus Lutz, 1889 for species with myxospores in gallbladders of amphibians
    Ashlie Hartigan
    University of Sydney, New South Wales 2006, Australia
    Parasitology 139:478-96. 2012
    ..Spores of both species are produced in the gallbladder. Spores of C. axonis sp. n. possess distinct filiform polar appendages (FPA)...
  23. ncbi A new species of Sphaeromyxa (Myxosporea: Sphaeromyxina: Sphaeromyxidae) in devil firefish, Pterois miles (Scorpaenidae), from the northern Red Sea: morphology, ultrastructure, and phylogeny
    A Diamant
    Israel Oceanographic and Limnological Research Ltd, National Center for Mariculture, Eilat 88112, Israel
    J Parasitol 90:1434-42. 2004
    Sphaeromyxa zaharoni n. sp. (Myxosporea) is described from the gallbladder of devil firefish, Pterois miles (Scorpaenidae), from coral reefs of the Gulf of Eilat, Israel, northern Red Sea...
  24. ncbi Frequent and significant K-ras mutation in the pancreas, the bile duct, and the gallbladder in autoimmune pancreatitis
    Terumi Kamisawa
    Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan
    Pancreas 38:890-5. 2009
    ..To assess the relationship between autoimmune pancreatitis (AIP) and pancreatic cancer, we analyzed K-ras mutation in the pancreatobiliary tissues of patients with AIP...
  25. ncbi Interstitial Cajal-like cells in human gallbladder
    Mihail E Hinescu
    Department of Cellular and Molecular Medicine, Carol Davila University of Medicine and Pharmacy, PO Box 35 29 Bucharest 35, Romania
    J Mol Histol 38:275-84. 2007
    We describe here an interstitial Cajal-like cell type (ICLC) in human gallbladder, resembling the archetypal enteric interstitial cells of Cajal...
  26. ncbi Sitosterolemia in ABC-transporter G5-deficient mice is aggravated on activation of the liver-X receptor
    Torsten Plosch
    Center for Liver, Digestive and Metabolic Diseases, University Hospital Groningen, Groningen, The Netherlands
    Gastroenterology 126:290-300. 2004
    ..It has been proposed that ABCG5/ABCG8 heterodimers mediate secretion of plant sterols and cholesterol by hepatocytes into bile and their efflux from enterocytes into the intestinal lumen...
  27. ncbi Sonographic diagnosis of biliary atresia in pediatric patients using the "triangular cord" sign versus gallbladder length and contraction
    Kimio Kanegawa
    Department of Radiology, Kobe Children s Hospital, 1 1 1 Takakuradai Suma ku, Kobe 654 0081, Japan
    AJR Am J Roentgenol 181:1387-90. 2003
    A retrospective review was performed to evaluate the importance of the "triangular cord" sign in comparison with gallbladder length and contraction for the diagnosis of biliary atresia in pediatric patients.
  28. ncbi Relationship between pain symptoms and referred sensory and trophic changes in patients with gallbladder pathology
    Maria Adele Giamberardino
    Ce S I, G d Annunzio Foundation, G D Annunzio University of Chieti, Pescara, Italy
    Pain 114:239-49. 2005
    The relationship was investigated between algogenic potential of gallbladder pathology and occurrence/extent of sensory and trophic changes in the referred area...
  29. doi Salmonella infection of gallbladder epithelial cells drives local inflammation and injury in a model of acute typhoid fever
    Alfredo Menendez
    Michael Smith Laboratories, Division of Anatomy and Cell Biology, Life Sciences Centre, University of British Columbia, Vancouver, Canada
    J Infect Dis 200:1703-13. 2009
    The gallbladder is often colonized by Salmonella during typhoid fever, yet little is known about bacterial pathogenesis in this organ...
  30. pmc Percutaneous radiofrequency ablation of hepatocellular carcinomas adjacent to the gallbladder with internally cooled electrodes: assessment of safety and therapeutic efficacy
    Sang Won Kim
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Korean J Radiol 10:366-76. 2009
    ..this study was to evaluate the safety and therapeutic efficacy of percutaneous radiofrequency (RF) ablation for the treatment of hepatocellular carcinomas (HCCs) adjacent to the gallbladder with the use of internally cooled electrodes.
  31. ncbi Lost gallstones in laparoscopic cholecystectomy: all possible complications
    Jörg Zehetner
    Department of Surgery, Ludwig Boltzmann Institute for Operative Laparoscopy, AKH Linz, Krankenhausstrasse 9, 4020 Linz, Austria
    Am J Surg 193:73-8. 2007
    ..The aim of this review is to categorize these complications and to evaluate the frequency and management of lost gallstones...
  32. ncbi Gallbladder carcinoma: radiologic-pathologic correlation
    A D Levy
    Department of Radiologic Pathology, Armed Forces Institute of Pathology, 6825 16th St NW, Bldg 54, Rm M 121, Washington, DC 20306 6000, USA
    Radiographics 21:295-314; questionnaire, 549-55. 2001
    Primary carcinoma of the gallbladder is an uncommon, aggressive malignancy that affects women more frequently than men. Older age groups are most often affected, and coexisting gallstones are present in the vast majority of cases...
  33. ncbi Megalin and cubilin expression in gallbladder epithelium and regulation by bile acids
    Benjamín Erranz
    Center for Cell Regulation and Pathology Joaquin V Luco, Departamento de Biologia Celular y Molecular, Facultad de Ciencias Biologicas, Pontificia Universidad Catolica de Chile, and Instituto Milenio de Biología Fundamental y Aplicada, Santiago, Chile
    J Lipid Res 45:2185-98. 2004
    Cholesterol crystal formation in the gallbladder is a key step in gallstone pathogenesis. Gallbladder epithelial cells might prevent luminal gallstone formation through a poorly understood cholesterol absorption process...
  34. ncbi Ultrasound measurement of gallbladder wall thickening as a diagnostic test and prognostic indicator for severe dengue in pediatric patients
    James A Colbert
    Stanford University School of Medicine, Stanford, CA, USA
    Pediatr Infect Dis J 26:850-2. 2007
    b>Gallbladder wall thickening measured by ultrasound was significantly associated with severe dengue, as well as with hallmark features of thrombocytopenia and elevated hematocrit/hemoconcentration, in children with suspected dengue in ..
  35. ncbi Micronutrients, antioxidants, and carcinoma of the gallbladder
    Vijay Kumar Shukla
    Department of Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
    J Surg Oncol 84:31-5. 2003
    ..This study was undertaken to test the above hypothesis in patients with carcinoma of the gallbladder.
  36. ncbi Activated Src and Ras induce gefitinib resistance by activation of signaling pathways downstream of epidermal growth factor receptor in human gallbladder adenocarcinoma cells
    Baoli Qin
    First Department of Internal Medicine and Department of Biosystemic Science of Medicine, Graduate School of Medicine, Kyushu University, 3 1 1 Maidashi, 812 8582, Higashi ku, Fukuoka, Japan
    Cancer Chemother Pharmacol 58:577-84. 2006
    ..In this study, we investigated the mechanistic role of Src and Ras, major oncogene products implicated in the pathogenesis of many human cancers in gefitinib sensitivity...
  37. ncbi Functional magnetic resonance cholangiography (fMRC) of the gallbladder and biliary tree with contrast-enhanced magnetic resonance cholangiography
    Laura M Fayad
    The Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    J Magn Reson Imaging 18:449-60. 2003
    ..To determine the diagnostic performance of functional magnetic resonance cholangiography (fMRC) for the evaluation of anatomic and functional biliary disorders...
  38. ncbi Real-time sonography for screening of gallbladder dysfunction in children with type 1 diabetes mellitus
    I Arslanoglu
    Department of Pediatrics, Göztepe Educational Hospital of SSK, Turkey
    J Pediatr Endocrinol Metab 14:61-9. 2001
    The aim of this study was to evaluate the occurrence of gallbladder dysfunction in children with type 1 diabetes mellitus using real-time ultrasonography. The study population consisted of 20 diabetic children (11 male, 9 female; age 11...
  39. ncbi Microbiology of gallbladder bile in uncomplicated symptomatic cholelithiasis
    Vasitha Abeysuriya
    Department of Clinical Anatomy, Faculty of Medicine, Ragama, Sri Lanka
    Hepatobiliary Pancreat Dis Int 7:633-7. 2008
    ..Few studies have assessed microflora and their antibiotic sensitivity in normal bile and lithogenic bile with different types of gallstones...
  40. ncbi Brush cells of rodent gallbladder and stomach epithelia express neurofilaments
    Liliana Luciano
    Department of Cell Biology, Center of Anatomy, Hannover Medical School, Hannover, Germany
    J Histochem Cytochem 51:187-98. 2003
    ..b>Gallbladder and stomach specimens from mice and rats, respectively, were fixed in various solutions, embedded either in ..
  41. ncbi [Incidentalomas of the liver and gallbladder. Evaluation and therapeutic procedure]
    Carl Zülke
    Chirurgische Klinik und Poliklinik, Universitatsklinikum Regensburg
    Chirurg 78:698-712. 2007
    ..The stage-oriented radical re-resection following diagnosis of an incidentally detected gallbladder cancer may lead to significantly improved long-term survival, especially in the early tumour stages T1b and T2, ..
  42. pmc An unusual cause of cholecystitis: heterotopic pancreatic tissue in the gallbladder
    Gulsum Ozlem Elpek
    Akdeniz University, Medical School, Department of Pathology, Yeni Tip, Dekanlik, 07070, Antalya, Turkey
    World J Gastroenterol 13:313-5. 2007
    b>Gallbladder localization of heterotopic pancreas (HP) is uncommon and very rarely gives rise to symptoms. Herein we report a case of HP found in the gallbladder neck presented with signs and symptoms of cholecystitis...
  43. ncbi Profile of gallbladder diseases diagnosed at Afyon Kocatepe University: a retrospective study
    Mustafa Mazlum
    Department of Pathology, Afyon Kocatepe University, Faculty of Medicine, Afyonkarahisar, Turkey
    Turk Patoloji Derg 27:23-30. 2011
    b>Gallbladder is one of the most commonly encountered specimen in a pathology laboratory. A diverse spectrum of diseases affect the biliary system, often presenting with similar clinical signs and symptoms...
  44. ncbi Evidence that gallbladder epithelial mucin enhances cholesterol cholelithogenesis in MUC1 transgenic mice
    Helen H Wang
    Department of Medicine, Liver Center and Gastroenterology Division, Beth Israel Deaconess Medical Center, Harvard Medical School and Harvard Digestive Diseases Center, Boston, Massachusetts 02215, USA
    Gastroenterology 131:210-22. 2006
    The gel-forming mucins play an important role in the early stage of cholesterol gallstone formation. We investigated whether the gallbladder epithelial mucin encoded by mucin gene 1 (MUC1) influences susceptibility to gallstones.
  45. ncbi Transient reticular gallbladder wall thickening in severe dengue fever: a reliable sign of plasma leakage
    Gabriel Antonio Oliveira
    Nossa Senhora da Gloria Children s Hospital, Rua Mary Ubirajara 205, Vitoria, Brazil
    Pediatr Radiol 40:720-4. 2010
    ..The main feature of this severe form of DF is plasma leakage. Gallbladder wall thickening (GBWT), ascites and pleural effusion represent the sonographic triad of plasma leakage in DF.
  46. doi Mixed adenoneuroendocrine carcinoma (MANEC) of the gallbladder: a possible stem cell tumor?
    Alberto E Paniz Mondolfi
    Department of Pathology and Laboratory Medicine, St Luke s Roosevelt Hospital Center, St Luke s Division, Clark 4, 1111 Tenth Avenue, New York, NY 10025, USA
    Pathol Int 61:608-14. 2011
    ..A PET-CT of the abdomen and pelvis demonstrated hypermetabolic, polypoid masses within the gallbladder and several tumors in the left lobe of the liver for which she underwent diagnostic laparoscopy...
  47. doi Abnormalities of the gallbladder, clinical effects
    J P Faure
    Service Chirurgie Viscérale Digestive et Endocrinienne, Hopital Jean Bernard, CHU Poitiers, Universite de Poitiers, 2 rue de la Miletrie, BP 577, 86021 Poitiers Cedex, France
    Surg Radiol Anat 30:285-90. 2008
    ..literature was to present and discuss the anatomical and embryological basis of congenital abnormalities of the gallbladder, based on a case of volvulus...
  48. ncbi Subcellular localization of the ABCG2 transporter in normal and malignant human gallbladder epithelium
    Sylvia Aust
    Department of Pathophysiology, Medical University of Vienna, Vienna, Austria
    Lab Invest 84:1024-36. 2004
    Epithelium of the gallbladder and biliary tract is exposed to high concentrations of potentially harmful exogenous and endogenous compounds excreted into primary bile...
  49. ncbi Contrast enhanced sonography of the gallbladder: a tool in the diagnosis of cholecystitis?
    Boris Adamietz
    Institute of Radiology, University of Erlangen, Maximiliansplatz 1, 91054 Erlangen, Germany
    Eur J Radiol 61:262-6. 2007
    To evaluate if contrast enhanced sonography (CES) can help to detect gallbladder inflammation and differentiate between acute and chronic cholecystitis.
  50. doi [Right liver agenesis with ectopic gallbladder and bile duct calculi]
    R Boufettal
    Gastroenterol Clin Biol 32:405-7. 2008
  51. ncbi Abnormal peritoneal fold connecting the greater omentum with the liver, gallbladder, right kidney and lesser omentum
    Satheesha B Nayak
    Melaka Manipal Medical College Manipal Campus, International Centre for Health Sciences, Madhav Nagar, Manipal, Udupi District, Karnataka State, India
    Bratisl Lek Listy 110:736-7. 2009
    ..fold of peritoneum that extended from the upper right part of the greater omentum and stomach to the fossa for gallbladder. This fold merged with the lesser omentum on the left and extended to the right kidney when traced posteriorly...
  52. doi Gallbladder bed irrigation with bupivacaine improves pulmonary functions after laparoscopic cholecystectomy
    Hunsu Alptekin
    Department of Surgery, Selcuklu Medical Faculty, Selcuk University, 42075, Konya, Turkey
    Langenbecks Arch Surg 395:501-4. 2010
    Afferent stimulus arising from gallbladder and its bed may elicit reflex inhibition of the diaphragm. Pulmonary function would be improved by blocking this stimulus after laparoscopic cholecystectomy...
  53. doi Gallbladder stent placement for prevention of cholecystitis in patients receiving covered metal stent for malignant obstructive jaundice: a feasibility study
    Sonia Gosain
    Digestive Health Center, University of Virginia Health System, Charlottesville, VA 22908 0708, USA
    Dig Dis Sci 55:2406-11. 2010
    ..Occlusion of the cystic duct by CSEMS may be complicated by cholecystitis. This potentially could be prevented by placement of a transpapillary gallbladder stent (GBS).
  54. doi Accurate staging for gallbladder cancer: implications for surgical therapy and pathological assessment
    Hiromichi Ito
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Ann Surg 254:320-5. 2011
    This study evaluates the significance of tumor involvement of the liver in early T-stage tumors and lymph node (LN) metastases on outcome after R0 resection of gallbladder cancer (GBCA).
  55. ncbi Gallbladder wall thickening in mononucleosis syndromes
    K Yamada
    Department of General Internal Medicine, Seirei Hamamatsu General Hospital, 2-12-12 Sumiyoshi, Hamamatsu 430-8558, Japan
    J Clin Ultrasound 29:322-5. 2001
    PURPOSE: We used sonography to measure gallbladder wall thickness in patients with mononucleosis syndromes and then evaluated laboratory data, spleen size, and clinical evolution to assess any relationship between gallbladder wall ..
  56. pmc Aberrant maspin expression in gallbladder epithelium is associated with intestinal metaplasia in patients with cholelithiasis
    C Maesawa
    Department of Pathology, Iwate Medical University School of Medicine, Uchimaru 19 1, 020 8505 Morioka, Japan
    J Clin Pathol 59:328-30. 2006
    ..expression of maspin protein related to DNA hypomethylation in the promoter region is frequently observed in gallbladder carcinomas, whereas the non-tumorous gallbladder epithelium is maspin negative...
  57. ncbi Agenesis of the gallbladder with hypoplastic cystic duct diagnosed at laparoscopy
    A Hon Kwon
    Department of Surgery, Kansai Medical University, Osaka, Japan
    Surg Laparosc Endosc Percutan Tech 16:251-4. 2006
    ..Ultrasonography of the abdomen showed dilated extrahepatic bile ducts containing stones; however, the gallbladder was not clearly identified...
  58. ncbi Cholecystitis, gallstones and free radical reactions in human gallbladder
    P Sipos
    2nd Department of Surgery, Semmelweis University, Budapest, Kútvölgyi u 4, H 1125 Hungary
    Med Sci Monit 7:84-8. 2001
    The relationship between biophysical and biochemical processes of gallbladder bile and free radical reactions is still not known...
  59. doi Design and application of a new series of gallbladder endoscopes that facilitate gallstone removal without gallbladder excision
    Tie Qiao
    The Second People s Hospital of Panyu District, Panyu, Guangzhou, People s Republic of China
    Rev Sci Instrum 83:015115. 2012
    In recent years, some Chinese doctors have proposed a new concept, gallstone removal without gallbladder excision, along with transition of the medical model...
  60. doi Expression of the p16(INK4a) gene product in premalignant and malignant epithelial lesions of the gallbladder
    Bridget C Lynch
    Department of Pathology, University of New Mexico School of Medicine, MSC 084640 Albuquerque, NM 87131 0001, USA
    Ann Diagn Pathol 12:161-4. 2008
    The sequence of molecular changes leading to neoplastic transformation in the gallbladder remains elusive...
  61. ncbi Biliary-hepatic recycling of a xenobiotic: gallbladder absorption of methyl mercury
    W J Dutczak
    Department of Biophysics, University of Rochester School of Medicine, New York 14642
    Am J Physiol 260:G873-80. 1991
    The role of the gallbladder in the disposition of methyl mercury was investigated in guinea pig, hamster, and macaque monkey...
  62. ncbi Changes in gallbladder motility and gallstone formation following laparoscopic gastric banding for morbid obestity
    Bilal O Al-Jiffry
    Departmentof General and Digestive Surgery, Flinders University of South Australia, Adelaide, Australia
    Can J Gastroenterol 17:169-74. 2003
    ..Morbid obesity is associated with cholesterol gallstone formation, a risk compounded by rapid weight loss. Laparoscopic gastric banding allows for a measured rate of weight loss, but the subsequent risk for developing gallstones is unknown...
  63. ncbi Diagnostic imaging of carcinomas of the gallbladder and the bile ducts
    H Oikarinen
    Department of Diagnostic Radiology, Oulu University Hospital, OYS, Finland
    Acta Radiol 47:345-58. 2006
    Early diagnosis and accurate staging of carcinomas of the gallbladder and the bile ducts are helpful in improving the prognosis...
  64. doi Identification of PEG10 and TSG101 as carcinogenesis, progression, and poor-prognosis related biomarkers for gallbladder adenocarcinoma
    Dong Cai Liu
    Department of Geriatric Surgery, Central South University, Changsha, Hunan 410011, China
    Pathol Oncol Res 17:859-66. 2011
    ..However, their expression and clinical significance in gallbladder cancer (GBC) have not yet been identified...
  65. doi Left-sided gallbladder with right-sided ligamentum teres hepatis: rare associated anomaly of exomphalos
    Rhim Si-Youn
    Division of Pediatric Surgery, Department of Surgery College of Medicine, Hanyang University, Seoul 133 791, South Korea
    J Pediatr Surg 43:1390-5. 2008
    The aim of this investigation was to establish the association of left-sided gallbladder and right-sided ligamentum teres hepatis with exomphalos and to clarify the portal venous anomaly associated with right-sided ligamentum teres.
  66. ncbi Hepatic artery pseudoaneurysm associated with cholecystitis that ruptured into the gallbladder
    Tomotaka Akatsu
    Department of Surgery, Keio University School of Medicine, Tokyo, Japan
    J Gastroenterol 39:900-3. 2004
    ..Color-Doppler ultrasound imaging showed a pulsatile wave pattern in an echogenic lesion inside the gallbladder. Contrast-enhanced computed tomography demonstrated a 3-cm pseudoaneurysm in the distended gallbladder...
  67. ncbi Comparison of sonography and scintigraphy in the evaluation of gallbladder functional studies with cholecystokinin
    Richard G Barr
    Radiology Consultants, Inc, Youngstown, OH 44512, USA
    J Ultrasound Med 28:1143-7. 2009
    Both sonography and scintigraphy have been used to evaluate gallbladder function with the use of sincalide (cholecystokinin [CCK]). However, the reported ejection fractions (EFs) for the two modalities are not the same...
  68. pmc Osmotic water permeability of Necturus gallbladder epithelium
    C U Cotton
    Department of Physiology and Biophysics, University of Texas Medical Branch, Galveston 77550
    J Gen Physiol 93:649-79. 1989
    ..content and has good temporal resolution was used to determine the hydraulic permeability (Lp) of Necturus gallbladder epithelium...
  69. ncbi Ellipsomyxa gobii (Myxozoa: Ceratomyxidae) in the common goby Pomatoschistus microps (Teleostei: Gobiidae) uses Nereis spp. (Annelida: Polychaeta) as invertebrate hosts
    Marianne Køie
    Marine Biological Laboratory, University of Copenhagen, DK 3000 Helsingør, Denmark
    Folia Parasitol (Praha) 51:14-8. 2004
    ..actinosporean stages developed into myxosporean stages of Ellipsomyxa gobii Køie, 2003 (Ceratomyxidae) in the gallbladder of the common goby Pomatoschistus microps (Krøyer) (Gobiidae). The European eel Anguilla anguilla (L...
  70. ncbi The marine herring myxozoan Ceratomyxa auerbachi (Myxozoa: Ceratomyxidae) uses Chone infundibuliformis (Annelida: Polychaeta: Sabellidae) as invertebrate host
    Marianne Køie
    Marine Biological Laboratory, University of Copenhagen, DK 3000 Helsingør, Denmark
    Folia Parasitol (Praha) 55:100-4. 2008
    ..This myxosporean was found in the gallbladder of the Atlantic herring Clupea harengus L...
  71. doi The significance of 99mTc-MAA SPECT/CT liver perfusion imaging in treatment planning for 90Y-microsphere selective internal radiation treatment
    Hojjat Ahmadzadehfar
    Department of Nuclear Medicine, University Hospital Bonn, Bonn, Germany
    J Nucl Med 51:1206-12. 2010
    ....
  72. pmc Helicobacter species and common gut bacterial DNA in gallbladder with cholecystitis
    Peren H Karagin
    Department of Medical Microbiology, Lund University, Solvegatan 23, SE 223 62 Lund, Sweden
    World J Gastroenterol 16:4817-22. 2010
    ..To analyze the association between Helicobacter spp. and some common gut bacteria in patients with cholecystitis...
  73. ncbi [Laparoscopic approach in gallbladder agenesis--an intraoperative surprise]
    M Beuran
    Clinica de Chirurgie, Spitalul Clinic de Urgenţă Bucureşti, Calea Floreasca Nr 8, Sector 1, 014461 Bucureşti, Romania
    Chirurgia (Bucur) 105:531-6. 2010
    The congenital absence of the gallbladder in the absence of biliary atresia is extremely rare, world literature recognizing only 413 cases. The aim of this study is to clarify the diagnostic and therapeutic approach of this rare condition.
  74. ncbi CT diagnosis of traumatic gallbladder injury
    Aaron Wittenberg
    Department of Radiology, MetroHealth Medical Center, Cleveland, OH 44109, USA
    AJR Am J Roentgenol 185:1573-4. 2005
  75. ncbi Effect of peroxisome proliferator-activated receptor-gamma ligand on inflammation of human gallbladder epithelial cells
    Guang Dong Pan
    PO Box 119, West China Medical University, Chengdu 610041, Sichuan Province, China
    World J Gastroenterol 11:6061-5. 2005
    ..receptor gamma (PPAR-gamma) and its ligand, ciglitazone, on inflammatory regulation of human gallbladder epithelial cells (HGBECs) and to assess the effect of human epithelial growth factor (hEGF) on growth of HGBECs.
  76. ncbi Unusual presentations of spilled gallstones
    M Yamamuro
    Department of General Surgery, The Cleveland Clinic Foundation, Cleveland, OH, USA
    Surg Endosc 17:1498. 2003
    Perforation of the gallbladder with resultant spillage of gallstones is not an uncommon occurrence. Spillage is reported to occur in 6% to 40% of laparoscopic cholecystectomies...
  77. ncbi Effects of ceftriaxone sodium on in vitro gallbladder contractility in guinea pigs
    Mehmet Arpacik
    Department of Pediatric Surgery, Cumhuriyet University School of Medicine, Sivas, Turkey
    J Surg Res 122:157-61. 2004
    It has been reported that ceftriaxone may induce the formation of gallstones. Changes of gallbladder motility may play a role in this phenomenon...
  78. ncbi Multiseptate gallbladder: diagnostic value of MR cholangiography and ultrasonography
    T Nakazawa
    Department of Internal Medicine and Bioregulation, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho cho, Mizuho ku, Nagoya 467 8601, Japan
    Abdom Imaging 29:691-3. 2004
    Multiseptate gallbladder is a rare congenital malformation. We present a case that emphasizes the importance of ultrasonography and magnetic resonance imaging...
  79. ncbi Aberrant expression of CDX2 in the metaplastic epithelium and inflammatory mucosa of the gallbladder
    Hiroyuki Osawa
    Am J Surg Pathol 28:1253-4. 2004
  80. ncbi Gallbladder agenesis with common bile duct stone--a rare case with a brief review of the literature
    Amit Mittal
    Maharishi Markandeshwar University, Institute of Medical Sciences and Research, Department of Radiology, Ambala, Haryana, India
    Turk J Gastroenterol 22:216-8. 2011
    ..the case of a 45-year-old female who presented with obstructive jaundice and was diagnosed as agenesis of the gallbladder with choledocholithiasis...
  81. pmc Diagnosis and laparoscopic approach to gallbladder torsion and cholelithiasis
    Patricio Cruz Garciavilla
    Gastrointestinal Surgery Department, Hospital Español de México
    JSLS 14:147-51. 2010
    Torsion of the gallbladder is common in elderly women. Different causes have been proposed for this rare condition. The presence of a long mesentery and loss of visceral fat are the main causes for the development of torsion...
  82. doi Rare coincidence of congenital short and annular pancreas with gallbladder agenesis and splenic malrotation
    M K Demir
    Radiology Department, Trakya University School of Medicine, Edirne, Turkey
    Br J Radiol 81:e204-6. 2008
    We present an adult patient with anomalies of congenital short and annular pancreas, gallbladder agenesis and splenic malrotation...
  83. ncbi Can biliary atresia be diagnosed by ultrasonography alone?
    Shigeru Takamizawa
    Department of Surgery, Kobe Children s Hospital, Kobe 654 0081, Japan
    J Pediatr Surg 42:2093-6. 2007
    ..We evaluated whether BA can be diagnosed by ultrasonography alone using 3 findings: TCS, gallbladder length (GBL), and gallbladder contractility (GBC).
  84. doi Gallbladder agenesis with a stone in the cystic duct bud
    Masaharu Ishida
    Department of Gastroenterological Surgery, Tohoku University Graduate School of Medicine, 1 1 Seiryocho, Aobaku, Sendai 980 8574, Japan
    J Hepatobiliary Pancreat Surg 15:220-3. 2008
    ..Abdominal computed tomography and magnetic resonance imaging failed to demonstrate the gallbladder, but showed a gallstone in a duct-like structure parallel to the common bile duct...
  85. doi Cross-sectional imaging of acute and chronic gallbladder inflammatory disease
    Ethan A Smith
    Department of Radiology, University of Michigan Health System, 1500 E Medical Center Dr, Ann Arbor, MI 48109 5030, USA
    AJR Am J Roentgenol 192:188-96. 2009
    The purpose of this article is to provide a comprehensive review of the clinical and cross-sectional imaging features of a variety of acute and chronic gallbladder inflammatory diseases.
  86. ncbi Effectiveness for pain after laparoscopic cholecystectomy of 0.5% bupivacaine-soaked Tabotamp placed in the gallbladder bed: a prospective, randomized, clinical trial
    Francesco Feroci
    General Surgery Unit, Misericordia and Dolce Hospital, Prato, Italy
    Surg Endosc 23:2214-20. 2009
    ..for pain control after video-laparoscopic cholecystectomy at its optimal dosage of 2 mg/kg infiltrated in the muscular fasciae of the trocars, or positioned in the gallbladder soaking a sheet of regenerated oxidized cellulose (Tabotamp).
  87. ncbi Two new Myxidium species (Myxosporea: Myxidiidae) infecting the gallbladder of African flying fish, Cheilopogon nigricans and Suez fusilier, Caesio suevicus from the Red Sea, Egypt: a morphological and morphometric study
    Abdel Azeem Sh Abdel-Baki
    Zoology Department, College of Science, King Saud University, P O Box 12455, Riyadh, 11451, Saudi Arabia
    Parasitol Res 105:513-8. 2009
    Myxidium maamouni sp. n. and Myxidium aydai sp. n. were described from the gallbladder of the African flying fish Cheilopogon nigricans and Suez fusilier Caesio suevicus, respectively...
  88. ncbi Multiseptate gallbladder
    Enid Y Rivera-Troche
    School of Medicine, Duke University, Durham, NC, USA
    J Gastrointest Surg 13:1741-3. 2009
    Multiseptate gallbladder is a rare congenital condition that may be asymptomatic or may lead to symptoms consistent with biliary colic, even in the absence of cholelithiasis.
  89. ncbi Extrahepatic biliary atresia with cartilaginous metaplasia in the gallbladder remnants
    E Altamirano
    Department of Pathology, Superiora Sor Maria Ludovica Children s Hospital, La Plata, Argentina
    J Clin Pathol 61:965-6. 2008
    ..A similar finding is presented here, but in the gallbladder of an infant with the full-blown manifestations of EBA; it is proposed that the alteration results from ..
  90. pmc Morphological and physiological evidence for interstitial cell of Cajal-like cells in the guinea pig gallbladder
    Brigitte Lavoie
    Department of Anatomy, University of Vermont College of Medicine, Burlington, VT 05405, USA
    J Physiol 579:487-501. 2007
    b>Gallbladder smooth muscle (GBSM) exhibits spontaneous rhythmic electrical activity, but the origin and propagation of this activity are not understood...
  91. ncbi Helicobacter pylori DNA in gallbladder tissue of patients with cholelithiasis and cholecystitis
    Kuaybe Yucebilgili
    Department of Biology, Faculty of Science and Literature, Fatih University, Turkey
    J Infect Dev Ctries 3:856-9. 2009
    Earlier reports on the detection of H. pylori DNA in gallbladder tissue of patients with cholelithiasis and cholecystitis gave discordant results. Our aim was to detect the presence of H...
  92. ncbi Gallbladder wall inflammatory cells in pediatric patients with biliary dyskinesia and cholelithiasis: a pilot study
    Brian Rau
    University of Missouri Kansas City, Kansas City, MO, USA
    J Pediatr Surg 41:1545-8. 2006
    ..This study was undertaken to evaluate gallbladder wall inflammatory cells in children with abdominal pain related to gallstones and biliary dyskinesia to ..
  93. ncbi Hartmann's gallbladder pouch revisited 60 years later
    F C van Eijck
    Department of Surgery, Medisch Centrum Rijnmond Zuid, Rotterdam, The Netherlands
    Surg Endosc 21:1122-5. 2007
    Hartmann's gallbladder pouch was the subject of an article in The Lancet 60 years ago. It has regained new interest in view of laparoscopic cholecystectomy. However, different opinions exist with regard to its incidence and nature...
  94. ncbi Effect of ursodeoxycholic acid on inflammatory infiltrate in gallbladder muscle of cholesterol gallstone patients
    S Carotti
    Department of Biomedical Research CIR, University Campus Bio Medico, Rome, Italy
    Neurogastroenterol Motil 22:866-73, e232. 2010
    Reduced gallbladder (GB) contractility and chronic inflammatory changes in the mucosa have been reported in patients with cholesterol gallstones (GS)...
  95. ncbi Does Helicobacter pylori identification in the mucosa of the gallbladder correlate with cholesterol gallstone formation?
    J Griniatsos
    First Department of Surgery, University of Athens, Medical School, Laiko Hospital, GR 115 27, Athens, Greece
    West Indian Med J 58:428-32. 2009
    ..In this study, any possible association between the H pylori identification in the mucosa of gallbladder and cholesterol gallstone formation was evaluated
  96. pmc Ultrasonic diagnosis of biliary atresia: a retrospective analysis of 20 patients
    Shi Xing Li
    Department of Ultrasound, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China
    World J Gastroenterol 14:3579-82. 2008
    ..To investigate the clinical value of ultrasonographic diagnosis of biliary atresia (BA), a retrospective analysis of the sonogram of 20 children with BA was undertaken...
  97. ncbi Cholecystokinin cholescintigraphy: detection of abnormal gallbladder motor function in patients with chronic acalculous gallbladder disease
    D Fink-Bennett
    Nuclear Medicine Department, William Beaumont Hospital, Royal Oak, MI 48073 6769
    J Nucl Med 32:1695-9. 1991
    ..performed in 374 patients with recurrent postprandial right upper quadrant pain, biliary colic, and a normal gallbladder sonogram and/or cholecystogram...
  98. ncbi Measurements of gallbladder motor function by ultrasonography: towards standardization
    P Portincasa
    Section of Internal Medicine, Department of Internal Medicine and Public Medicine, University Medical School of Bari, Piazza G Cesare, 70124 Bari, Italy
    Dig Liver Dis 35:S56-61. 2003
    ..easy, validated and reproducible technique, it can be repeated over time to document time-related changes of gallbladder motor function...
  99. ncbi Volvulus of the gallbladder: laparoscopic detorsion and removal
    S Y Kim
    Department of Surgery, Abington Memorial Hospital, Abington, PA 19001, USA
    Surg Endosc 17:1849. 2003
    A 73-year-old woman who presented with symptoms of acute cholecystitis was found to have a gangrenous gallbladder wrapped in three complete rotations around its pedicle...
  100. ncbi Expression of the GLUT1 glucose transporter in gallbladder carcinomas
    Youn Wha Kim
    Department of Pathology, School of Medicine Kyung Hee University, Seoul, Korea
    Hepatogastroenterology 49:907-11. 2002
    ..We hypothesized that human erythrocyte glucose transporter-1 expression is increased in gallbladder carcinoma and might be correlated with prognostic significance.
  101. ncbi Gallbladder motility in obesity, diabetes mellitus and coeliac disease
    M Fraquelli
    University of Milan, Milan, Italy
    Dig Liver Dis 35:S12-6. 2003
    We reviewed data on gallbladder motility in obesity, diabetes and coeliac disease...

Research Grants73

  1. A Microfluidic-platform Mini-Liver System for Human Liver Biology Studies
    HONGSEOK M NOH; Fiscal Year: 2010
    ..The hepatic portal vein carries blood from the intestines, pancreas, spleen and gallbladder and exposes the liver to nutrients and toxins derived from these sources...
  2. A Microfluidic-platform Mini-Liver System for Human Liver Biology Studies
    MICHAEL BOUCHARD; Fiscal Year: 2009
    ..The hepatic portal vein carries blood from the intestines, pancreas, spleen and gallbladder and exposes the liver to nutrients and toxins derived from these sources...
  3. SURGICAL STUDIES ON METABOLISM OF G I HORMONES
    James Thompson; Fiscal Year: 1991
    ..We plan to study the mechanisms of actions of CCK on gallbladder (GB) smooth muscle...
  4. PHYSICAL CHEMISTRY OF BILIRUBIN & ITS CONJUGATES
    WILLIAM SPIVAK; Fiscal Year: 1990
    ..We prostulated that continuous non-enzymatic alkaline hydrolysis of BMG to UCB within the gallbladder (or within the bile ductules in cholestasis) may be the major source of precipitated UCB and its derivatives, ..
  5. Pilot Prospective Study of Minor Papilla Endoscopic Sphincterotomy for Pancreas D
    Joseph Romagnuolo; Fiscal Year: 2010
    ..g. chronic pancreatitis, gallbladder)...
  6. UNIVERSITY OF NEW MEXICO CANCER CENTER PLANNING GRANT
    Cheryl Willman; Fiscal Year: 2000
    ..types of cancer that are common in non-Hispanic Whites, both Indians and Hispanics have had very high rates of gallbladder, stomach, and cervix cancer in the past several decades...
  7. UNIVERSITY OF NEW MEXICO CANCER CENTER PLANNING GRANT
    Cheryl Willman; Fiscal Year: 2001
    ..types of cancer that are common in non-Hispanic Whites, both Indians and Hispanics have had very high rates of gallbladder, stomach, and cervix cancer in the past several decades...
  8. UNIVERSITY OF NEW MEXICO CANCER CENTER PLANNING GRANT
    Cheryl Willman; Fiscal Year: 2002
    ..types of cancer that are common in non-Hispanic Whites, both Indians and Hispanics have had very high rates of gallbladder, stomach, and cervix cancer in the past several decades...
  9. UNIVERSITY OF NEW MEXICO CANCER CENTER PLANNING GRANT
    Cheryl Willman; Fiscal Year: 2003
    ..types of cancer that are common in non-Hispanic Whites, both Indians and Hispanics have had very high rates of gallbladder, stomach, and cervix cancer in the past several decades...
  10. UNIVERSITY OF NEW MEXICO CANCER CENTER PLANNING GRANT
    Cheryl Willman; Fiscal Year: 2004
    ..types of cancer that are common in non-Hispanic Whites, both Indians and Hispanics have had very high rates of gallbladder, stomach, and cervix cancer in the past several decades...
  11. Mechanism of gallbladder tumorigenesis in BK5.erbB2 mice
    Kaoru Kiguchi; Fiscal Year: 2005
    ..All of these factors render gallbladder cancer nearly incurable with a five year survival rate of only 5-21%...
  12. Mechanism of gallbladder tumorigenesis in BK5.erbB2 mice
    Kaoru Kiguchi; Fiscal Year: 2006
    ..All of these factors render gallbladder cancer nearly incurable with a five year survival rate of only 5-21%...
  13. Mechanism of gallbladder tumorigenesis in BK5.erbB2 mice
    Kaoru Kiguchi; Fiscal Year: 2007
    ..All of these factors render gallbladder cancer nearly incurable with a five year survival rate of only 5-21%...
  14. EICOSANOIDS IN GALLBLADDER PHYSIOLOGY AND DISEASE
    DONALD KAMINSKI; Fiscal Year: 1991
    ..In experimental models of cholecystitis, cyclooxygenase inhibitors decrease gallbladder inflammation...
  15. Improved Surgical Treatment of Pelvic Organ Prolapse
    KEITH LIPFORD; Fiscal Year: 2009
    ..into one that is done primarily laparoscopically, similar to what occurred with cholecystectomy (removal of the gallbladder)...
  16. NEURAL CONTROL OF THE GALLBLADDER
    Gary Mawe; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): Decreased contractility is a hallmark of gallbladder disorders, and it is associated with inflammation and gallstone formation...
  17. NEURAL CONTROL OF THE GALLBLADDER
    Gary M Mawe; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Decreased contractility is a hallmark of gallbladder disorders, and it is associated with inflammation and gallstone formation...
  18. NUTRITION COMPONENTS ALTER CHOLESTEROL METABOLISM
    BERTRAM COHEN; Fiscal Year: 1992
    ..components, fiber and fat, in the regulation of cholesterol balance and changes occurring in hepatic and gallbladder bile in two animal models of cholesterol cholelithiasis, namely, the prairie dog and the hamster...
  19. CNS AUTONOMIC REGULATION BY ELECTROACUPUNCTURE
    John Longhurst; Fiscal Year: 2001
    ..In this model, stimulation of gallbladder chemosensitive afferent nerve endings reflexly increased arterial blood pressure, and augmented myocardial ..
  20. CNS AUTONOMIC REGULATION BY ELECTROACUPUNCTURE
    John Longhurst; Fiscal Year: 2000
    ..In this model, stimulation of gallbladder chemosensitive afferent nerve endings reflexly increased arterial blood pressure, and augmented myocardial ..
  21. CNS AUTONOMIC REGULATION BY ELECTROACUPUNCTURE
    John Longhurst; Fiscal Year: 2002
    ..In this model, stimulation of gallbladder chemosensitive afferent nerve endings reflexly increased arterial blood pressure, and augmented myocardial ..
  22. Bile, Biofilms and Salmonella Gallbladder Carriage
    John S Gunn; Fiscal Year: 2010
    Infection with Salmonella typhi can cause a chronic, relatively asymptomatic infection of the human gallbladder. S. typhi carriers are responsible for much of the human-to-human spread of typhoid fever...
  23. EFFECT OF MUCIN HYPERSECRETION ON GALLBLADDER PHYSIOLOGY
    Mitchell Shiffman; Fiscal Year: 1991
    b>Gallbladder mucin (GMB) plays an important role in gallstone (GS) pathogenesis. Mucin is found within both cholesterol (XOL) and black pigment GS...
  24. Bile, Biofilms and Salmonella Gallbladder Carriage
    John Gunn; Fiscal Year: 2007
    Infection with Salmonella typhi can cause a chronic, relatively asymptomatic infection of the human gallbladder. S. typhi carriers are responsible for much of the human-to-human spread of typhoid fever...
  25. Bile, Biofilms and Salmonella Gallbladder Carriage
    John Gunn; Fiscal Year: 2009
    Infection with Salmonella typhi can cause a chronic, relatively asymptomatic infection of the human gallbladder. S. typhi carriers are responsible for much of the human-to-human spread of typhoid fever...
  26. BILIARY EPITHELIAL CELLS; BIOLOGY AND PATHOBIOLOGY
    NICOLA TAVOLONI; Fiscal Year: 1991
    ..of hepatic bile flow and composition (individual bile acids, electrolytes, phospholipids, and cholesterol) and gallbladder bile composition; 2) determination of the effects of bile acids, secretin, glucagon, and insulin on bile flow ..
  27. Extracellular Replication of Listeria in Vivo
    Christopher Contag; Fiscal Year: 2009
    ..We have recently identified the gallbladder as a potential reservoir of bacteria in symptomatic and asymptomatic infected mice, and have determined that ..
  28. Extracellular Replication of Listeria in Vivo
    Christopher H Contag; Fiscal Year: 2010
    ..We have recently identified the gallbladder as a potential reservoir of bacteria in symptomatic and asymptomatic infected mice, and have determined that ..
  29. NEURAL CONTROL OF THE GALLBLADDER
    Gary Mawe; Fiscal Year: 1990
    A great deal of morbidity is caused by diseases of the gallbladder; nevertheless, the control of the motile and absorptive functions of the organ are incompletely understood...
  30. Fibroblast Growth Factor Regulation in the Pancreas
    Sam Holmstrom; Fiscal Year: 2009
    ..Our recent studies show that fibroblast growth factor 15 (FGF15) is a secreted endocrine hormone that promotes gallbladder filling and opposes CCK-induced contraction of the gallbladder (9)...
  31. Fibroblast Growth Factor Regulation in the Pancreas
    Sam Holmstrom; Fiscal Year: 2007
    ..Our recent studies show that fibroblast growth factor 15 (FGF15) is a secreted endocrine hormone that promotes gallbladder filling and opposes CCK-induced contraction of the gallbladder (9)...
  32. PATHOGENESIS OF CALCIUM-CONTAINING GALLSTONES
    Edward Moore; Fiscal Year: 1990
    ..forces in modulating free biliary (Ca++); (6) CaCO3 solubility and lithogenicity in bile; (7) the role of gallbladder mucosal function (H+ secretion) in calcium solubility; (8) bilirubin ionization and solubility; (9) solute ..
  33. MYOGENIC DISORDERS OF THE GALLBLADDER
    Jose Behar; Fiscal Year: 2000
    Acute cholecystitis (AC) affects 88% of patients with symptomatic gallbladder (GB) stones over a 18 year period and has a significant morbidity and mortality in elderly patients...
  34. MYOGENIC DISORDERS OF THE GALLBLADDER
    Jose Behar; Fiscal Year: 2001
    Acute cholecystitis (AC) affects 88% of patients with symptomatic gallbladder (GB) stones over a 18 year period and has a significant morbidity and mortality in elderly patients...
  35. DYNAMICS OF RETINOPATHY AMONG MEXICAN AMERICAN DIABETICS
    Craig Hanis; Fiscal Year: 1990
    ..diabetics will be added to this group through random sampling in Starr County during ongoing investigations of gallbladder disease...
  36. MYOGENIC DISORDERS OF THE GALLBLADDER
    Jose Behar; Fiscal Year: 2004
    Acute cholecystitis (AC) affects 88% of patients with symptomatic gallbladder (GB) stones over a 18 year period and has a significant morbidity and mortality in elderly patients...
  37. MYOGENIC DISORDERS OF THE GALLBLADDER
    Jose Behar; Fiscal Year: 2002
    Acute cholecystitis (AC) affects 88% of patients with symptomatic gallbladder (GB) stones over a 18 year period and has a significant morbidity and mortality in elderly patients...
  38. MYOGENIC DISORDERS OF THE GALLBLADDER
    Jose Behar; Fiscal Year: 2003
    Acute cholecystitis (AC) affects 88% of patients with symptomatic gallbladder (GB) stones over a 18 year period and has a significant morbidity and mortality in elderly patients...
  39. Cross-sectional and prospective cohort data analysis of physical activity and hea
    Paul Williams; Fiscal Year: 2009
    ..35%), macular degeneration (54%), hypertension (30%), hypercholesterolemia (47%), diabetes (68%), gout (45%), gallbladder disease (52%), diverticular disease (48%), benign prostate hyperplasia (33%), and nonfatal stroke (60%)...
  40. Cross-sectional and prospective cohort data analysis of physical activity and hea
    Paul T Williams; Fiscal Year: 2010
    ..35%), macular degeneration (54%), hypertension (30%), hypercholesterolemia (47%), diabetes (68%), gout (45%), gallbladder disease (52%), diverticular disease (48%), benign prostate hyperplasia (33%), and nonfatal stroke (60%)...
  41. CONTROL OF MOTILITY IN THE SPHINCTER OF ODDI
    Gary Mawe; Fiscal Year: 1992
    ..This system, which includes the gallbladder, the biliary ducts, and the sphincter of Oddi (SO), must work as a unit to store and concentrate bile between ..
  42. Mechanisms Regulating Gastrointestinal Hormone Secretion
    Rodger A Liddle; Fiscal Year: 2011
    ..Cholecystokinin (CCK) is a prototypical gastrointestinal hormone that regulates gallbladder contraction, pancreatic enzyme secretion, delays gastric emptying, and induces satiety...
  43. CONTROL OF MOTILITY IN THE SPHINCTER OF ODDI
    Gary Mawe; Fiscal Year: 1993
    ..This system, which includes the gallbladder, the biliary ducts, and the sphincter of Oddi (SO), must work as a unit to store and concentrate bile between ..
  44. Function and Regulatin of Intestinal Basolateral Organic Solute Transporters
    Anuradha Rao; Fiscal Year: 2009
    Project Summary: Bile acids are secreted by the liver, stored in the gallbladder, and efficiently reabsorbed from the intestine...
  45. PATHOGENESIS OF MULTIPLE ORGAN FAILURE
    FRANK MOODY; Fiscal Year: 1990
    ..The investigators will test the hypothesis that splanchnic organ failure (liver, gallbladder, pancreas and gut) is a primary early event in the syndrome...
  46. BIOSYNTHESIS OF GASTROINTESTINAL HORMONES
    Andrew Leiter; Fiscal Year: 1990
    ..polypeptide, produced in the pancreatic islets, inhibits pancreatic exocrine secretion and relaxes the gallbladder. Peptide YY, which is made in endocrine cells of the colon and ileum, also inhibits pancreatic exocrine ..
  47. OCCUPATIONAL MORTALITY--CALIFORNIA HISPANIC POPULATION
    James Beaumont; Fiscal Year: 1993
    ..For example, tumors of the gallbladder, stomach, cervix, and liver occur excessively in the Hispanic population of the U.S...
  48. CELLULAR MECHANISMS OF CHOLECYSTITIS AND COLITIS
    DONALD KAMINSKI; Fiscal Year: 1999
    ..Previous studies have demonstrated that cyclooxygenase inhibitors are specific drugs for the treatment of gallbladder disease...
  49. Function and Regulatin of Intestinal Basolateral Organic Solute Transporters
    Anuradha Rao; Fiscal Year: 2007
    Project Summary: Bile acids are secreted by the liver, stored in the gallbladder, and efficiently reabsorbed from the intestine...
  50. PATHOPHYSIOLOGIC EFFECTS OF PERITONITIS
    Harvey Sugerman; Fiscal Year: 1980
    ..Another catheter will be implanted in the devascularized obstructed gallbladder. After 48 hours, frozen, processed human feces mixed with barium sulfate will be injected under pressure into ..
  51. ROLE OF THE GALLBLADDER IN PATHOGENESIS OF GALLSTONES
    LESTER WILLIAMS; Fiscal Year: 1990
    ..Patients with GS or pregnancy and animals with GA have gallbladder (GB stasis...
  52. CHOLESTEROL TRANSPORT IN GALLBLADDER EPITHELIAL CELLS
    Rahul Kuver; Fiscal Year: 2002
    b>Gallbladder epithelial cells and cholangiocytes are exposed to high concentrations of cholesterol because the major pathway of cholesterol excretion from the body is through bile...
  53. NEURAL CONTROL OF THE GALLBLADDER
    Gary Mawe; Fiscal Year: 1993
    The overall aim of this study is to determine how gallbladder function is influenced by the neurons that lie within the wall of the gallbladder...
  54. Isolation, Identification and Characterization of a Toxin Causing Biliary Atresia
    REBECCA G contact WELLS; Fiscal Year: 2011
    ..fractions with a complexity of 2-20 that, remarkably, cause a BA-like pattern of injury (with atresia of the gallbladder and extrahepatic biliary tree) in zebrafish larvae exposed after biliary morphogenesis has occurred, mimicking ..
  55. Neural Substrates of EA in Cardiovascular Control
    John Longhurst; Fiscal Year: 2005
    ..EA inhibits premotor sympathoexcitatory neurons that receive convergent input from the median and splanchnic (gallbladder) nerves...