Genomes and Genes
Summary: A group of organs stretching from the MOUTH to the ANUS, serving to breakdown foods, assimilate nutrients, and eliminate waste. In humans, the digestive system includes the GASTROINTESTINAL TRACT and the accessory glands (LIVER; BILIARY TRACT; PANCREAS).
Publications246 found, 100 shown here
- Bacteria in midguts of field-collected Anopheles albimanus block Plasmodium vivax sporogonic developmentLilia Gonzalez-Ceron
Centro de Investigacion de Paludismo, Instituto Nacional de Salud Publica, Mexico
J Med Entomol 40:371-4. 2003..The overall midgut bacterial infection in mosquito field populations may influence P. vivax transmission, and could contribute to explain the annual variations in malaria incidence observed in the area...
- Inter- and intraspecific comparison of the bacterial assemblages in the hindgut of humivorous scarab beetle larvae (Pachnoda spp.)Janet Andert
Department of Biogeochemistry, Max Planck Institute for Terrestrial Microbiology, Marburg, Germany
FEMS Microbiol Ecol 74:439-49. 2010..A comparison with a previously obtained clone library of the same species corroborates both the similarities and the intraspecific variance of the hindgut microbiota...
- Insect-microbe mutualism without vertical transmission: a stinkbug acquires a beneficial gut symbiont from the environment every generationYoshitomo Kikuchi
Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan
Appl Environ Microbiol 73:4308-16. 2007....
- Hemocyte differentiation mediates innate immune memory in Anopheles gambiae mosquitoesJanneth Rodrigues
Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20892, USA
Science 329:1353-5. 2010..In mosquitoes, differentiation of hemocytes was necessary and sufficient to confer innate immune memory...
- Acetic acid bacteria, newly emerging symbionts of insectsElena Crotti
Dipartimento di Scienze e Tecnologie Alimentari e Microbiologiche DISTAM, Universita degli Studi di Milano, 20133 Milan, Italy
Appl Environ Microbiol 76:6963-70. 2010..Taken together, the data indicate that AAB represent novel secondary symbionts of insects...
- Hensen's node gives rise to the ventral midline of the foregut: implications for organizing head and heart developmentMargaret L Kirby
Neonatal Perinatal Research Institute, Division of Neonatology, Department of Pediatrics, Box 3179, Duke University Medical Center, Durham, NC 27710, USA
Dev Biol 253:175-88. 2003....
- The ultrastructural investigation of the midgut in the quill mite Syringophilopsis fringilla (Acari, Trombidiformes: Syringophilidae)S A Filimonova
Zoological Institute, Parasitology, Russian Academy of Sciences, Universitetskaya embankment 1, 199034 St Petersburg, Russia
Arthropod Struct Dev 38:303-13. 2009..Evacuation of the fecal masses occurs periodically. Mitotic figures have been observed occasionally in the epithelial cells of the anterior midgut...
- Proteophosphoglycan confers resistance of Leishmania major to midgut digestive enzymes induced by blood feeding in vector sand fliesNagila Secundino
Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, MD 20892, USA
Cell Microbiol 12:906-18. 2010....
- Detection and identification of a novel lactic acid bacterial flora within the honey stomach of the honeybee Apis melliferaTobias C Olofsson
Microbiology Laboratory at Campus Helsingborg, Department of Cell and Organism Biology, Lund University Campus Helsingborg, P O Box 882, Helsingborg, 25108, Sweden
Curr Microbiol 57:356-63. 2008....
- Mining an Ostrinia nubilalis midgut expressed sequence tag (EST) library for candidate genes and single nucleotide polymorphisms (SNPs)B S Coates
USDA ARS, Corn Insect and Crop Genetics Research Unit, Genetics Laboratory, Iowa State University, Ames, Iowa 50011, USA
Insect Mol Biol 17:607-20. 2008..This O. nubilalis larval midgut EST collection is a resource for gene discovery, expression information, and allelic variation for use in genetic marker development...
- Commensal host-bacterial relationships in the gutL V Hooper
Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St. Louis, MO 63110, USA
Science 292:1115-8. 2001....
- Distinct populations of endoderm cells converge to generate the embryonic liver bud and ventral foregut tissuesKimberly D Tremblay
Cell and Developmental Biology Program, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA
Dev Biol 280:87-99. 2005....
- A lipophosphoglycan-independent development of Leishmania in permissive sand fliesJitka Myskova
Department of Parasitology, Faculty of Science, Charles University, Vinicna 7, Prague 2, Czech Republic
Microbes Infect 9:317-24. 2007..infantum by Lutzomyia longipalpis; this event led to the establishment of L. infantum/chagasi in Latin America...
- Developmental microbial ecology of the neonatal gastrointestinal tractR I Mackie
Department of Animal Sciences, University of Illinois at Urbana Champaign, Urbana 61801, USA
Am J Clin Nutr 69:1035S-1045S. 1999..Further advances in our understanding of developmental microbial ecology in the neonatal gastrointestinal tract are dependent on the application of these modern molecular techniques...
- A simple model host for identifying Gram-positive virulence factorsD A Garsin
Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA
Proc Natl Acad Sci U S A 98:10892-7. 2001..We exploit the apparent parallels between Gram-positive infection in simple and more complex organisms by using the nematode to identify an E. faecalis virulence factor, ScrB, which is relevant to mammalian pathogenesis...
- Controls on gut phosphatisation: the trilobites from the Weeks Formation Lagerstätte (Cambrian; Utah)Rudy Lerosey-Aubril
Department of Palaeontology and Historical Geology, Senckenberg Research Institute, Frankfurt am Main, Germany
PLoS ONE 7:e32934. 2012..However, in some specimens from the Weeks Formation, the phosphatisation extends to the entire digestive system, suggesting that trilobites might have had some biological particularities not observed in modern arthropods...
- Stem cells of the beetle midgut epitheliumJames B Nardi
Department of Entomology, University of Illinois, 320 Morrill Hall, 505 S Goodwin Avenue, Urbana, IL 61801, United States
J Insect Physiol 56:296-303. 2010..This organization of stem cell pouches in insect midguts closely parallels that of regenerative crypts in mammalian intestines...
- Multilocus microsatellite markers for molecular typing of Candida glabrata: application to analysis of genetic relationships between bloodstream and digestive system isolatesA Enache-Angoulvant
AP HP, Hopital Bicetre, Service de Bactériologie Virologie Hygiène, Laboratoire de Parasitologie Mycologie, Kremlin Bicetre, France
J Clin Microbiol 48:4028-34. 2010..The demonstration of the occurrence of microevolution in digestive strains supports the idea that C. glabrata can be a persistent commensal of the human gut...
- Sec13 safeguards the integrity of the endoplasmic reticulum and organogenesis of the digestive system in zebrafishXuBo Niu
Key Laboratory for Molecular Animal Nutrition, Ministry of Education, College of Animal Sciences, Zhejiang University, Hangzhou, PR China
Dev Biol 367:197-207. 2012..Our data provide the first direct genetic evidence that COPII function is essential for the organogenesis of the digestive system.
- Plasmodium falciparum ookinete invasion of the midgut epithelium of Anopheles stephensi is consistent with the Time Bomb modelL A Baton
Institute of Biomedical and Life Sciences, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, UK
Parasitology 129:663-76. 2004....
- Characterization of a membrane-bound aminopeptidase purified from Acyrthosiphon pisum midgut cells. A major binding site for toxic mannose lectinsPlinio T Cristofoletti
Departamento de Bioquimica, Instituto de Quimica, Universidade de Sao Paulo, Brazil
FEBS J 273:5574-88. 2006..In addition to oligopeptide digestion, APN is proposed to be associated with amino-acid-absorption processes which, in contrast with aminopeptidase activity, may be hampered on lectin binding...
- A microarray-based analysis of transcriptional compartmentalization in the alimentary canal of Anopheles gambiae (Diptera: Culicidae) larvaeM Neira Oviedo
The Whitney Laboratory for Marine Bioscience, University of Florida, St Augustine, FL 32080, USA
Insect Mol Biol 17:61-72. 2008..Furthermore, our data support the notion that the region encompassing the hindgut and Malpighian tubes plays important roles in avoiding the excretion of nutrients, as well as in xenobiotic detoxification...
- Identification of novel Bacillus thuringiensis Cry1Ac binding proteins in Manduca sexta midgut through proteomic analysisRebecca J McNall
Department of Biochemistry and Molecular Biology, University of Georgia, 413 Biological Sciences Building, 120 Cedar Street, Athens, GA 30602, USA
Insect Biochem Mol Biol 33:999-1010. 2003..Aminopeptidase N was the only GPI-anchored protein identified. Actin, aminopeptidase N, and membrane alkaline phosphatase were confirmed as accurate protein identifications through western blots...
- Proteomic analysis of the mosquito Aedes aegypti midgut brush border membrane vesiclesAlexandra Popova-Butler
Department of Biochemistry, The Ohio State University, 484 West 12th Avenue, Columbus, OH 43210, USA
J Insect Physiol 55:264-72. 2009..Three proteins, arginine kinase, putative allergen and actin are shown to be the most predominant proteins in the sample. The total number of 36 proteins detected by both methods represents the most abundant proteins in the BBMV...
- Gut symbiotic bacteria of the genus Burkholderia in the broad-headed bugs Riptortus clavatus and Leptocorisa chinensis (Heteroptera: Alydidae)Yoshitomo Kikuchi
Natural History Laboratory, Faculty of Science, Ibaraki University, Mito 310 8512, Japan
Appl Environ Microbiol 71:4035-43. 2005..chinensis did not form clades but were intermingled in the phylogeny, suggesting that horizontal transmission of the symbiont might have occasionally occurred between populations and species of the bugs...
- Niche heterogeneity determines bacterial community structure in the termite gut (Reticulitermes santonensis)Hong Yang
Fachbereich Biologie, Mikrobielle Okologie, Universitat Konstanz, 78457 Konstanz, Germany
Environ Microbiol 7:916-32. 2005....
- Conserved mosquito/parasite interactions affect development of Plasmodium falciparum in AfricaAntonio M Mendes
Imperial College London, Division of Cell and Molecular Biology, Faculty of Natural Sciences, South Kensington Campus, London, United Kingdom
PLoS Pathog 4:e1000069. 2008..falciparum field isolates have been established by direct experimentation. Importantly, they validate for semi-field human malaria transmission the concept of parasite antagonists and agonists...
- The role of promastigote secretory gel in the origin and transmission of the infective stage of Leishmania mexicana by the sandfly Lutzomyia longipalpisM E Rogers
Division of Molecular Biology and Immunology, Liverpool School of Tropical Medicine, UK
Parasitology 124:495-507. 2002..Collectively, these data support the role of the PSG in the transmission of leishmaniasis, by conditioning the midgut environment for metacyclogenesis and altering the feeding ability of infected sandflies...
- Identification, cloning and expression of a Cry1Ab cadherin receptor from European corn borer, Ostrinia nubilalis (Hubner) (Lepidoptera: Crambidae)Ronald D Flannagan
Pioneer Hi Bred International Inc, 7301 NW 62nd Avenue, P O Box 85, Johnston, IA 50131 0085, USA
Insect Biochem Mol Biol 35:33-40. 2005..1 microg/ml. These results in combination suggest strongly that a cadherin-like protein acts as receptor and is involved with Cry1Ab toxicity in O. nubilalis...
- Temporal changes in outer surface proteins A and C of the lyme disease-associated spirochete, Borrelia burgdorferi, during the chain of infection in ticks and miceT G Schwan
Laboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840, USA
J Clin Microbiol 38:382-8. 2000..Therefore, the temporal synthesis of OspC by spirochetes only in feeding ticks that were infected prior to the blood meal suggests that this surface protein is involved in transmission from tick to mammal but not from mammal to tick...
- Leishmania chagasi: lipophosphoglycan characterization and binding to the midgut of the sand fly vector Lutzomyia longipalpisRodrigo P P Soares
Laboratory of Medical Entomology, Centro de Pesquisas Rene Rachou Fiocruz, Av Augusto de Lima, 1715, 30190 002, Belo Horizonte, MG, Brazil
Mol Biochem Parasitol 121:213-24. 2002..These results are consistent with the proposal that a New World Leishmania species, similar to Old World species, adapts the expression of terminally exposed sugars of its LPG to mediate parasite-sand fly interactions...
- Influence of combined intravenous and topical antibiotic prophylaxis on the incidence of infections, organ dysfunctions, and mortality in critically ill surgical patients: a prospective, stratified, randomized, double-blind, placebo-controlled clinical trWolfgang A Krueger
Department of Anesthesiology and Intensive Care Medicine, Tubingen University Hospital, Tubingen
Am J Respir Crit Care Med 166:1029-37. 2002..496-1.046). Surveillance cultures from tracheobronchial, oropharyngeal, and gastric secretions and from rectal swabs did not show any evidence for the selection of resistant microorganisms in the patients receiving prophylaxis...
- Functional genomic analysis of midgut epithelial responses in Anopheles during Plasmodium invasionDina Vlachou
European Molecular Biology Laboratory, Heidelberg, Germany
Curr Biol 15:1185-95. 2005..Previously, we have identified hemolymph factors that can antagonize or promote parasite development...
- Digestive lipases: from three-dimensional structure to physiologyN Miled
Laboratoire de Lipolyse Enzymatique, CNRS IFR1 UPR 9025, 31, Chemin Joseph Aiguier, 13402 cedex 20, Marseille, France
Biochimie 82:973-86. 2000..The biochemical, histochemical and clinical studies as well as the 3-D structures obtained will be a great help for a better understanding of the structure-function relationships of digestive lipases...
- Involvement of ghrelin-growth hormone secretagogue receptor system in pathoclinical profiles of digestive system cancerZhigang Wang
Department of General Surgery, Shanghai Jiaotong University Affiliated No 6 Hospital, Shanghai 200233, China
Acta Biochim Biophys Sin (Shanghai) 39:992-8. 2007..For the first time, we identified the distribution of ghrelin receptor in digestive system cancers...
- The fine structure of the midgut in the mite Anystis baccarum (L.) (Acari, Actinedida: Anystidae)Svetlana A Filimonova
Zoological Institute, Russian Academy of Sciences, 199034 St Petersburg, Russia
Arthropod Struct Dev 37:299-309. 2008..All types of secretory granules were observed close to the apical plasmalemma...
- Morphologic analysis of the zebrafish digestive systemAndrew J Trotter
Colon Molecular and Cell Biology Laboratory, Ludwig Institute for Cancer Research, Royal Melbourne Hospital, Parkville, Vic, Australia
Methods Mol Biol 546:289-315. 2009..Despite optical transparency of embryos, the internal position of the developing digestive system and its close juxtaposition with the yolk initially made morphological analysis relatively challenging, ..
- Rhou maintains the epithelial architecture and facilitates differentiation of the foregut endodermDavid A F Loebel
Embryology Unit, Children s Medical Research Institute, Westmead, NSW 2145, Australia
Development 138:4511-22. 2011....
- The peritrophic matrix limits the rate of digestion in adult Anopheles stephensi and Aedes aegypti mosquitoesJ M Villalon
Case Western Reserve University, School of Medicine, Department of Genetics, Cleveland, OH 44106, USA
J Insect Physiol 49:891-5. 2003..PM disruption by two independent means (chitinase and anti-PM antibodies) consistently increases the rate of blood digestion. The significance of these results in relation to PM function is discussed...
- Exceptionally preserved Cambrian trilobite digestive system revealed in 3D by synchrotron-radiation X-ray tomographic microscopyMats E Eriksson
Department of Geology, Lund University, Lund, Sweden
PLoS ONE 7:e35625. 2012..analogous to the labrum of euarthropods and that it was a sophisticated element closely integrated with the digestive system. This study also briefly addresses the preservational bias of the 'Orsten' fauna, particularly the near-..
- The effect of peptide absorption on PepT1 gene expression and digestive system hormones in rainbow trout (Oncorhynchus mykiss)Teresa Ostaszewska
Warsaw University of Life Sciences, Division of Ichthyobiology and Fisheries, Faculty of Animal Science, Ciszewskiego 8, 02 786 Warsaw, Poland
Comp Biochem Physiol A Mol Integr Physiol 155:107-14. 2010..Leptin immunoreactivity was also observed in hepatocyte cytoplasm and pancreatic acinar cells. Gastrin/CCK immunoreactive cells were present in the proximal intestine and pyloric caeca...
- Expression of nesfatin-1/NUCB2 in rodent digestive systemAi qing Zhang
Department of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, Jiangsu Province, China
World J Gastroenterol 16:1735-41. 2010To observe the regional distributions and morphological features of nesfatin-1/nucleobindin-2 (NUCB2) immunoreactive (IR) cells in the rodent digestive system.
- Expression profiling and comparative analyses of seven midgut serine proteases from the yellow fever mosquito, Aedes aegyptiDoug E Brackney
Arthropod Infectious Disease Laboratory, 1692 Campus Delivery, Department of Microbiology, Immunology and Pathology at Colorado State University, Fort Collins, CO 80523, USA
J Insect Physiol 56:736-44. 2010..A subfamily of midgut serine proteases and/or that A. aegypti has evolved an array of proteases with a broad range of substrate specificities for rapid, efficient digestion of bloodmeals...
- Indirect effects of temperature on stink bug fitness, via maintenance of gut-associated symbiontsSimone S Prado
Empresa Brasileira de Pesquisa Agropecuaria, Londrina, PR, Brazil
Appl Environ Microbiol 76:1261-6. 2010..This work illustrates the need to better understand the biology of animal-symbiont associations and the consequences of local climate for the dynamics of these interactions...
- Ultrastructural changes of the midgut epithelium in Isohypsibius granulifer granulifer Thulin, 1928 (Tardigrada: Eutardigrada) during oogenesisMagdalena M Rost-Roszkowska
Department of Animal Histology and Embryology, University of Silesia, Bankowa 9, 40 007, Katowice, Poland
Protoplasma 248:405-14. 2011..At the end of oogenesis, autophagy also intensifies in midgut epithelial cells, which is probably caused by the great amount of reserve material. Midgut epithelium of analyzed species takes part in the yolk precursor synthesis...
- Uptake, flow, and digestion of casein and green fluorescent protein in the digestive system of Lygus hesperus KnightJavad Habibi
Department of Entomology, University of Missouri, Columbia, USA
Arch Insect Biochem Physiol 50:62-74. 2002..Dextran was used as a control to monitor the non-absorptive flow rate of ingesta through the digestive system. Fluorescent tracking of FITC-conjugates of casein and dextran, as well as immunoblotting and ..
- Fine structure of the midgut epithelium in two Archaeognatha, Lepismachilis notata and Machilis hrabei (Insecta), in relation to its degeneration and regenerationMagdalena M Rost-Roszkowska
Department of Animal Histology and Embryology, University of Silesia, Bankowa 9, Katowice, Poland
Protoplasma 247:91-101. 2010..Some of them proliferate, while the others differentiate into epithelial cells. We compared the organisation of the midgut epithelium of M. hrabei and L. notata with zygentoman species, which have just been described...
- Vertebrate endoderm developmentJ M Wells
Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts 02138, USA
Annu Rev Cell Dev Biol 15:393-410. 1999..We discuss possible mechanisms that regulate how undifferentiated endoderm becomes specified into a myriad of cell types that populate the respiratory and gastrointestinal tracts...
- Prevention of ventilator-associated pneumonia by oral decontamination: a prospective, randomized, double-blind, placebo-controlled studyD C Bergmans
Department of Internal Medicine, University Hospital Maastricht, Maastricht, The Netherlands
Am J Respir Crit Care Med 164:382-8. 2001..cross infection, prevention and control; respiration, artificial, adverse effects; antibiotics, administration and dosage infection control methods; pneumonia, etiology, prevention and control; intubation, intratracheal, adverse effects..
- Microscopic anatomy of pycnogonida: II. Digestive system. III. Excretory systemW H Fahrenbach
Oregon National Primate Research Center, Oregon Health and Sciences University, Beaverton, Oregon 97006, USA
J Morphol 268:917-35. 2007The digestive system of several species of sea spiders (Pycnogonida, Arthropoda) was studied by electron microscopy. It is composed of the foregut inside a long proboscis, a midgut and a hindgut...
- Hypothermia does not increase the risk of infection: a case control studyMarlijn Kamps
Department of Intensive Care, Radboud University Nijmegen Medical Centre PO Box 9101, 6500 HB Nijmegen, The Netherlands
Crit Care 15:R48. 2011..The aim of this study was to investigate the incidence of infections in patients treated with hypothermia and normothermia while receiving SDD...
- Histological and ultrastructural characterization of the alimentary system of solifuges (Arachnida, Solifugae)A E Klann
Ernst Moritz Arndt Universitat Greifswald, Zoologisches Institut and Museum, Johann Sebastian Bach Strabetae 11 12, 17487 Greifswald, Germany
J Morphol 271:225-43. 2010..In contrast to the midgut, the epithelium of the hindgut consists of only one type of cell overlain by a thin cuticle. Digested residuals are stored in the hindgut until defecation...
- Interaction of two Bacillus thuringiensis delta-endotoxins with the digestive system of Lygus hesperusSandra L Brandt
Biological Control of Insects Research Laboratory, US Department of Agriculture, Agricultural Research Service, 1503 S Providence Rd, Columbia, MO 65203, USA
Curr Microbiol 48:1-9. 2004..Proteolytic processing of the toxins also occurred in vivo, within the digestive system of L. hesperus. Excreted CrylAc and Cry2Ab retained activity toward lepidopteran larvae...
- Effects of 17beta-estradiol on mussel digestive glandLaura Canesi
Dipartimento di Biologia, Universita di Genova, Corso Europa 26, 16132 Genova, Italy
Gen Comp Endocrinol 153:40-6. 2007....
- Organogenesis in the budding process of the freshwater bryozoan Cristatella mucedo Cuvier, 1798 (Bryozoa, Phylactolaemata)Thomas Schwaha
Department of Theoretical Biology, Morphology Section, University of Vienna, Althanstraße 14, 1090 Vienna, Austria
J Morphol 272:320-41. 2011..Nonetheless, our results show that comparative organogenesis can contribute to phylactolaemate systematics and, when more data are available, possibly to that of other bryozoan classes and bilaterian phyla...
- Characterization of proteases in the digestive system of spiny lobster (Panulirus interruptus)Laura E Celis-Guerrero
Centro de Investigaciones Biologicas del Noroeste CIBNOR, PO Box 129, La Paz, B C S 23000, Mexico
Mar Biotechnol (NY) 6:262-9. 2004..Also, such enzymes become alternative tools for use in biotechnologies...
- Metal accumulation and binding protein induction in Mytilus galloprovincialis, Scapharca inaequivalvis, and Tapes philippinarum from the Lagoon of VeniceP Irato
Department of Biology, University of Padova, Italy
Arch Environ Contam Toxicol 44:476-84. 2003..inaequivalvis are sentinel organisms and can be used specifically for Zn pollution; (3) T. philippinarum accumulates Cu in the digestive gland more readily than the other two bivalves and therefore has the highest MT...
- Ultrastructure of the midgut and hindgut of Derocheilocaris remanei (Crustacea, Mystacocarida)L Herrera-Alvarez
Departamento de Biología Animal I, Facultad de Biologia, Universidad Complutense, Madrid, Spain
J Morphol 244:177-89. 2000..A single basic cell type forms the hindgut epithelium. The suggested function for the hindgut is the transport and ejection of waste products...
- Endogenous beta-galactosidase activity in amphioxus: a useful histochemical marker for the digestive systemC Canestro
Departament de Genetica, Facultat de Biologia, Universitat de Barcelona, 645 Av Diagonal, 08028 Barcelona, Spain
Dev Genes Evol 211:154-6. 2001..of beta-galactosidase activity was used to monitor morphological and functional differentiation of the digestive system and the posteriorization of the endodermal structures in retinoic-acid treated embryos...
- Effects of dietary Pb on accumulation, histopathology, and digestive enzyme activities in the digestive system of tilapia (Oreochromis niloticus)Wei Dai
Key Laboratory for Molecular Animal Nutrition of Ministry of Education, Feed Science Institute, Zhejiang University, Hangzhou, 310029, People s Republic of China
Biol Trace Elem Res 127:124-31. 2009..the effects of dietary Pb on accumulation, histopathology, and digestive enzyme activities in tissues of the digestive system. The results showed that the Pb accumulation in tissues increased with the dietary Pb concentrations...
- Short-term effects of environmentally relevant concentrations of EDC mixtures on Mytilus galloprovincialis digestive glandLaura Canesi
Dipartimento di Biologia, Universita di Genova, Corso Europa 26, 16132 Genova, Italy
Aquat Toxicol 87:272-9. 2008..The results demonstrate that short-term exposure to environmentally relevant concentrations of EDC mixtures can interfere with the lysosomal function, redox-related enzyme activities and gene transcription of mussel digestive gland...
- Cellular expression of gut chitinase mRNA in the gastrointestinal tract of mice and chickensMasako Suzuki
Department of Veterinary Medicine, Faculty of Agriculture, Iwate University, Morioka, Japan
J Histochem Cytochem 50:1081-9. 2002....
- Effects of vibrio challenge on digestive gland biomarkers and antioxidant gene expression in Mytilus galloprovincialisLaura Canesi
Dipartimento di Biologia, Universita di Genova, Italy
Comp Biochem Physiol C Toxicol Pharmacol 152:399-406. 2010..Moreover, the results support the hypothesis that host responses to bacteria may be taken into account when interpreting biomarker data in ecotoxicological studies...
- Sequential allocation and global pattern of movement of the definitive endoderm in the mouse embryo during gastrulationPatrick P L Tam
Embryology Unit, Children s Medical Research Institute, University of Sydney, Locked Bag 23, Wentworthville, New South Wales 2145, Australia
Development 134:251-60. 2007..The observation that the endoderm cells are inherently unable to move despite the expansion of the mesoderm in the Mixl1-null mutant suggests that the movement of the endoderm and the mesoderm is driven independently of one another...
- Aquaporins in the digestive systemToshiyuki Matsuzaki
Department of Anatomy and Cell Biology, Gunma University Graduate School of Medicine, 3 39 22 Showa machi, Maebashi, Gunma 371 8511, Japan
Med Electron Microsc 37:71-80. 2004Fluid transfer such as secretion and absorption is one of the major functions of the digestive system. Aquaporins are water channel proteins providing water transfer across the cellular membrane...
- Can bacterial interference prevent infection?G Reid
Lawson Health Research Institute, University of Western Ontario, 268 Grosvenor Street, London, Ontario, Canada N6A 4V2
Trends Microbiol 9:424-8. 2001..The potential for new therapeutic regimens using probiotics is significant and worthy of further study...
- Nil per os encodes a conserved RNA recognition motif protein required for morphogenesis and cytodifferentiation of digestive organs in zebrafishAlan N Mayer
Cardiovascular Research Center, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA
Development 130:3917-28. 2003..Antisense-mediated knockdown of npo results in organ hypoplasia, and overexpression of npo causes an overgrowth of gastrointestinal organs. Thus, npo is a gene essential for a key step in the gut morphogenetic sequence...
- The Anopheles gambiae adult midgut peritrophic matrix proteomeR R Dinglasan
Department of Molecular Microbiology and Immunology, Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
Insect Biochem Mol Biol 39:125-34. 2009..Among them were nine new chitin-binding peritrophic matrix proteins, expanding the list from three to twelve peritrophins. Lastly, we provide a model for the putative interactions among the proteins identified in this study...
- Studies on cultured and uncultured microbiota of wild culex quinquefasciatus mosquito midgut based on 16s ribosomal RNA gene analysisVyankatesh J Pidiyar
Molecular Biology Unit, National Centre for Cell Science, University of Pune, Pune, India
Am J Trop Med Hyg 70:597-603. 2004....
- Gene expression patterns of Helicoverpa armigera gut proteasesNanasaheb P Chougule
National Chemical Laboratory, Plant Molecular Biology Unit, Division of Biochemical Sciences, Dr Homi Bhabha Road, Pune 411 008 MS, India
Insect Biochem Mol Biol 35:355-67. 2005..The proteases identified in the study would be ideal candidates for further interactions studies with protease inhibitors to understand the structural reasons of protease inhibitor insensitivity...
- Peritrophic matrix proteinsR L Tellam
CSIRO Tropical Agriculture, Queensland, Australia
Insect Biochem Mol Biol 29:87-101. 1999..The review concludes with speculation about the biological functions of the proteins in this matrix...
- Plasmodium falciparum ookinetes require mosquito midgut chondroitin sulfate proteoglycans for cell invasionRhoel R Dinglasan
Department of Molecular Microbiology and Immunology, Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
Proc Natl Acad Sci U S A 104:15882-7. 2007..We provide evidence for the in vivo role of chondroitin sulfate proteoglycans in Plasmodium falciparum invasion of the midgut and insight into the molecular mechanisms mediating parasite-mosquito interactions...
- Bacterial resistance and overgrowth due to selective decontamination of the digestive tractW Ebner
Institute of Environmental Medicine and Hospital Epidemiology, University Hospital Freiburg, Germany
Eur J Clin Microbiol Infect Dis 19:243-7. 2000..To date, none of the studies available for examination have been designed to adequately assess the effect of selective decontamination of the digestive tract on the bacterial flora...
- A comparative molecular study of the presence of "Candidatus arthromitus" in the digestive system of rainbow trout, Oncorhynchus mykiss (Walbaum), healthy and affected with rainbow trout gastroenteritisJ Del-Pozo
Department of Veterinary Pathology, Easter Bush Veterinary Centre, Roslin, Midlothian, UK
J Fish Dis 33:241-50. 2010..The results of this study showed that the presence of SFB was not invariably associated with clinical disease and that more information is required to understand the role of these organisms...
- Meconial peritrophic membranes and the fate of midgut bacteria during mosquito (Diptera: Culicidae) metamorphosisR M Moll
Department of Biomedical Sciences, Tropical Disease Institute, College of Osteopathic Medicine, Ohio University, Athens, OH 45701, USA
J Med Entomol 38:29-32. 2001....
- A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathwayD Ferrandon
Institut de Biologie Moleculaire et Cellulaire, UPR 9022 du Centre National de la Recherche Scientifique, 15, rue René Descartes, F67084 Strasbourg, France
EMBO J 17:1217-27. 1998..We also show that, in contrast to the systemic antifungal response, this local immune response is independent of the Toll pathway...
- The surface protein Pvs25 of Plasmodium vivax ookinetes interacts with calreticulin on the midgut apical surface of the malaria vector Anopheles albimanusMaria del Carmen Rodriguez
Centro De Investigacion sobre Enfermedades Infecciosas, Instituto Nacional de Salud Publica, Cuernavaca, Morelos, Mexico
Mol Biochem Parasitol 153:167-77. 2007..The Pvs25-calreticulin interaction in vivo could represent a potential target for developing transmission blocking strategies based on interfering the parasite-midgut interaction...
- Contribution of gut bacteria to digestion and development of the velvetbean caterpillar, Anticarsia gemmatalisL E Visôtto
Departamento de Bioquimica e Biologia Molecular, Instituto de Biotecnologia Aplicada à Agropecuária BIOAGRO, Universidade Federal de Vicosa, Vicosa, MG 36571 000, Brazil
J Insect Physiol 55:185-91. 2009....
- Regulatory peptides in fruit fly midgutJan A Veenstra
CNIC UMR 5228 CNRS, Universite Bordeaux 1, 33400, Talence, France
Cell Tissue Res 334:499-516. 2008..Although the Drosophila insulin gene Ilp3 was abundantly expressed in the midgut, Ilp3 was not expressed in endocrine cells, but in midgut muscle...
- Formation of the digestive system in zebrafish. I. Liver morphogenesisHolly A Field
Department of Biochemistry and Biophysics, Programs in Developmental Biology, Genetics and Human Genetics, University of California, San Francisco, San Francisco, CA 94143, USA
Dev Biol 253:279-90. 2003Despite the essential functions of the digestive system, much remains to be learned about the cellular and molecular mechanisms responsible for digestive organ morphogenesis and patterning...
- Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endodermJianwen Que
Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
Development 134:2521-31. 2007..These findings suggest that Sox2 plays a second role in establishing the boundary between the keratinized, squamous esophagus/forestomach and glandular hindstomach...
- Real-time, in vivo analysis of malaria ookinete locomotion and mosquito midgut invasionDina Vlachou
European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
Cell Microbiol 6:671-85. 2004..Similar observations were made in both A. gambiae and A. stephensi, demonstrating the conservation of P. berghei interactions with these vectors...
- Essential role of membrane-attack protein in malarial transmission to mosquito hostKimie Kadota
Mie University School of Medicine, Mie 514 0001, Japan
Proc Natl Acad Sci U S A 101:16310-5. 2004....
- Storage and secretion of the peritrophic matrix protein Ag-Aper1 and trypsin in the midgut of Anopheles gambiaeM Devenport
Department of Genetics, Case Western Reserve University, Cleveland, OH, USA
Insect Mol Biol 13:349-58. 2004..Newly synthesized Ag-Aper1 protein was again detected within the midgut epithelial cells at 60 h after blood ingestion...
- The movement of proteins across the insect and tick digestive systemLaura A Jeffers
Department of Entomology, Dearstyne Entomology Building, North Carolina State University, Raleigh, NC 27695 7647, USA
J Insect Physiol 54:319-32. 2008The movement of intact proteins across the digestive system was shown in a number of different blood-feeding and non-blood-feeding insects in the orders Blattaria, Coleoptera, Diptera, Hemiptera, Lepidoptera, Orthoptera, Neuroptera and ..
- Sex-specific and blood meal-induced proteins of Anopheles gambiae midguts: analysis by two-dimensional gel electrophoresisG I Prévot
Ecologie des Systèmes Vectoriels, Institut Pasteur, 25 rue du Dr Roux, 75724 Paris Cedex15, France
Malar J 2:1. 2003..Characterisation of An. gambiae midgut proteins may identify the proteins that render An. gambiae receptive to the malaria parasite...
- Insulin regulates aging and oxidative stress in Anopheles stephensiMi Ae Kang
Department of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, One Shields Avenue, Davis, CA 95616, USA
J Exp Biol 211:741-8. 2008....
- Cowpea bruchid Callosobruchus maculatus counteracts dietary protease inhibitors by modulating propeptides of major digestive enzymesJ E Ahn
Department of Entomology, Texas A and M University, College Station, Texas 77843, USA
Insect Mol Biol 16:295-304. 2007....
- A systematic quantification of carbonic anhydrase transcripts in the mouse digestive systemPei wen Pan
Institute of Medical Technology, University of Tampere and Tampere University Hospital, 33520, Tampere, Finland
BMC Mol Biol 8:22. 2007..In the present study, we systematically examined the mRNA expression levels of all known CA isozymes by quantitative real-time PCR in eight tissues of the digestive system of male and female mice.
- Anatomical and functional characterisation of the stomatogastric nervous system of blowfly (Calliphora vicina) larvaeAndreas Schoofs
Institut fur Zoologie, Abteilung Neurobiologie, Universitat Bonn, Poppelsdorfer Schloss, 53115 Bonn, Germany
J Insect Physiol 53:349-60. 2007..The dorsal organs (DOs) are directly connected to the SNS. Mechanical stimulation of the DOs evokes sensory activity in the AN. This suggests the DOs can provide sensory input for temporal coordination of feeding behaviour...
- Lutzomyia longipalpis peritrophic matrix: formation, structure, and chemical compositionN F C Secundino
Laboratory of Medical Entomology Centro de Pesquisas René Rachou, Fundacao Oswaldo Cruz, Minas Gerais, Brazil
J Med Entomol 42:928-38. 2005..7-135 kDa, induced by the protein-free diet. Mouse polyclonal antiserum was produced against PMs induced by protein-free meal and used in Western blotting, which revealed at least three associated proteins...
- Anopheles gambiae Croquemort SCRBQ2, expression profile in the mosquito and its potential interaction with the malaria parasite Plasmodium bergheiMónica González-Lázaro
Department of Cell Biology, Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico Nacional, Mexico City, Mexico
Insect Biochem Mol Biol 39:395-402. 2009..Interestingly, knockdown of SCRBQ2 expression by dsRNA injection resulted in a 62.5% inhibition of oocyst formation, suggesting that SCRBQ2 plays a role in Plasmodium-mosquito interactions...
- Digestive system of the sacoglossan Plakobranchus ocellatus (Gastropoda: Opisthobranchia): light- and electron-microscopic observations with remarks on chloroplast retentionEuichi Hirose
Department of Chemistry, Biology and Marine Science, Faculty of Science, University of the Ryukyus, Nishihara, Okinawa 903 0213, Japan
Zoolog Sci 22:905-16. 2005..Morphology of the entire digestive system of this species was firstly described by means of a combination of histology and electron microscopy (both ..
- FMRFamide-like immunoreactivity in the central nervous system and alimentary tract of the non-hematophagous blow fly, Phormia regina, and the hematophagous horse fly, Tabanus nigrovittatusAaron T Haselton
Department of Biology, State University of New York at New Paltz, New Paltz, NY, USA
J Insect Sci 8:1-17. 2008....
- Analysis of midgut proteinases from Bacillus thuringiensis-susceptible and -resistant Heliothis virescens (Lepidoptera: Noctuidae)Lohitash Karumbaiah
Department of Entomology, University of Georgia, Athens, GA 30602, USA
Comp Biochem Physiol B Biochem Mol Biol 146:139-46. 2007..Because serine proteinases are a critical component of Bt toxin mode of action, these differences may contribute to decreased toxicity in the Bt-resistant strains...
- Cloning and characterization of trypsin- and chymotrypsin-like proteases from the midgut of the sand fly vector Phlebotomus papatasiJ M Ramalho-Ortigão
Intracellular Parasite Biology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, 4 Center Drive, Building 4, Room 126, MSC 0425, NIH, Bethesda, MD 20892 0425, USA
Insect Biochem Mol Biol 33:163-71. 2003..The two chymotrypsin-like enzymes display expression behavior similar to that of the early and late trypsins from Ae. aegypti...
- A new approach reveals syncytia within the visceral musculature of Drosophila melanogasterR Klapper
Institut für Allgemeine Zoologie und Genetik der Westfälischen Wilhelms Universität, Schlossplatz 5, 48149 Munster, Germany
Development 128:2517-24. 2001..This novel application of the transplantation technique might be a powerful tool to trace syncytia in any organism using the GAL4/UAS system...
- SOAP, a novel malaria ookinete protein involved in mosquito midgut invasion and oocyst developmentJohannes T Dessens
Department of Biological Sciences, Sir Alexander Fleming Building, Imperial College London, South Kensington Campus, SW7 2AZ, UK
Mol Microbiol 49:319-29. 2003..These results identify SOAP as a key molecule for ookinete-to-oocyst differentiation in mosquitoes...
- The formation of syncytia within the visceral musculature of the Drosophila midgut is dependent on duf, sns and mbcRobert Klapper
Institut für Allgemeine Zoologie und Genetik der Westfälischen Wilhelms Universität, Schlossplatz 5, 48149 Munster, Germany
Mech Dev 110:85-96. 2002..Our results provide strong evidence that the founder-cell hypothesis also applies to visceral myogenesis, employing the same genetic components as are used in the somatic myoblast fusion processes...
- Immunolocalization of the water channel, aquaporin-5 (AQP5), in the rat digestive systemToshiyuki Matsuzaki
Department of Anatomy and Cell Biology, Gunma University Graduate School of Medicine, Maebashi, Japan
Arch Histol Cytol 66:307-15. 2003..We surveyed the expression and immunohistochemical localization of AQP5 in the rat digestive system. RT-PCR analysis revealed that AQP5 is expressed in the submandibular gland, tongue, gastric corpus, pyloric ..
- Absorption and tissue distribution of cholesterol in Manduca sextaZeina E Jouni
Department of Biochemistry and Molecular Biophysics, Center of Insect Science, Biological Sciences West, University of Arizona, Tucson, 85721 0088, USA
Arch Insect Biochem Physiol 49:167-75. 2002..Cholesterol-labeled lipophorin injected into larval hemolymph was cleared from the hemolymph with a half-life of 10.2 h. After 17 h, most of the cleared radioactivity was recovered in the fat body (38%). Arch...
- REGULATION OF DIGESTION IN BLOOD-SUCKING INSECTSMichael Wells; Fiscal Year: 1993..A. aegypti uses a trypsin-based digestive system, whereas R. prolixus uses a cathepsin-based digestive system. In A...
- Spatiotemporal Regulation of Intestinal Gene ExpressionEric Sibley; Fiscal Year: 2010Lactase non-persistence (adult-type hypolactasia) results in digestive system malabsorption of lactose, the carbohydrate macronutrient present in milk...
- Spatiotemporal Regulation of Intestinal Gene ExpressionEric Sibley; Fiscal Year: 2010Lactase non-persistence (adult-type hypolactasia) results in digestive system malabsorption of lactose, the carbohydrate macronutrient present in milk...
- Functional Brain Imaging and Appetite-Related Hormones Pre and Post Obesity SurgeAllan Geliebter; Fiscal Year: 2010..Changes in brain responses to food stimuli as well as changes in appetite hormones produced by the digestive system will be assessed following two types of obesity surgery: 1) gastric bypass and 2) gastric banding...
- FUNCTION OF KERATIN AND 14-3-3 PROTEIN ASSOCIATIONM Omary; Fiscal Year: 2001..Our proposed studies are likely to generate important new biologic information regarding two major protein families in the digestive system, and help clarify their function and potential role in human disease.
- Expression of Human Therapeutic Proteins in Transgenic Tobacco ChloroplastsHenry Daniell; Fiscal Year: 2010..of therapeutic proteins expressed in plant cells offers several advantages including protection in the digestive system by bioencapsulation, followed by slow release in the gut;elimination of expensive purification steps, the ..
- Expression of Human Therapeutic Proteins in Transgenic Tobacco ChloroplastsHenry Daniell; Fiscal Year: 2009..of therapeutic proteins expressed in plant cells offers several advantages including protection in the digestive system by bioencapsulation, followed by slow release in the gut; elimination of expensive purification steps, the ..
- Expression of Human Therapeutic Proteins in Transgenic Tobacco ChloroplastsHenry Daniell; Fiscal Year: 2006..of therapeutic proteins expressed in plant cells offers several advantages including protection in the digestive system by bioencapsulation, followed by slow release in the gut; elimination of expensive purification steps, the ..
- The role of Wnt signaling in the development of the veterbrate visceral mesodermValerie McLin; Fiscal Year: 2007..Developmental biology of the digestive system aims to further the understanding of both congenital and acquired forms of pediatric gastrointestinal disease ..
- DIET, DISEASE, AND PANCREATIC ENZYME SYNTHESIS IN HUMANSSTEPHEN O KEEFE; Fiscal Year: 2004..are expected to provide valuable new information on both the stimulatory effects of food on the human digestive system and the nutritional value of modern nutritional support techniques, and help determine why elemental diets ..
- Characterization of a mutation that affects feeding and digestion in DrosophilaEDWARD BLUMENTHAL; Fiscal Year: 2007..In focusing on a mutation in the fruit fly Drosophila that affects digestion and feeding behavior, this project will provide insight into the function of the human digestive system and its role in appetite control.
- Genetics of Taste PerceptionAlexander Bachmanov; Fiscal Year: 2009..Taste also influences food processing by the digestive system. Consequently, understanding the mechanisms underlying this sense is central to our ability to control intake ..
- Genetics of Taste PerceptionAlexander A Bachmanov; Fiscal Year: 2010..Taste also influences food processing by the digestive system. Consequently, understanding the mechanisms underlying this sense is central to our ability to control intake ..
- DUKE/NIDDK FUNCTIONAL GENOMICS CENTERJoseph Nevins; Fiscal Year: 2002..specialized DNA microarrays, that will specifically and uniquely enhance studies directed at the kidney and digestive system. This will be accomplished by generating cDNA and SAGE libraries so as to identify expressed sequences that ..
- Formation of the Enteric Nervous SystemChen Ming Fan; Fiscal Year: 2010..They control the movement, secretion, and absorption of the digestive system. Deficiency of enteric neurons causes abdominal distention and constipation, a condition of patients ..
- NEUROPEPTIDE REGULATION OF ENTEROPANCREATIC FUNCTIONMichael Mulholland; Fiscal Year: 1993Until recent years it was believed that the functions of the digestive system were controlled by the two classical divisions of the autonomic nervous system acting in concert with established gastrointestinal hormones...
- Epidemiology of Celiac Disease: A Population Based StudyJoseph A Murray; Fiscal Year: 2010Celiac disease (CD) is one of the most common chronic diseases of the digestive system, and is readily treatable with exclusion of dietary gluten...
- Epidemiology of Celiac Disease: A Population Based StudyJoseph Murray; Fiscal Year: 2007Celiac disease (CD) is one of the most common chronic diseases of the digestive system, and is readily treatable with exclusion of dietary gluten...
- Fate Mapping and Analysis of the Definitive EndodermKimberly Tremblay; Fiscal Year: 2005..Together these studies will provide for a more thorough understanding of the processes leading to the formation of a normal digestive system, allowing for the advancement of therapies for the diseased state.
- Mechanisms of alimentary chemosensationSteven D Munger; Fiscal Year: 2010..In Aim 2, we will characterize the role of two hormones expressed in taste cells and in the digestive system, glucagon-like peptide-1 (GLP-1) and glucagon, in the modulation of taste sensitivity...
- Regulation of Digestive Vesicular Glutamate TransporterLiqun Bai; Fiscal Year: 2007..The long-term goal of our laboratory is to study the regulation of vesicular glutamate transporter in digestive system. The primary purpose of this proposal is to determine the mechanisms of glucose-induced regulation of ..
- Regulation and Dynamics of Keratins in Digestive OrgansM Omary; Fiscal Year: 2006..Our proposed studies are likely to generate important new biologic information regarding keratins in the digestive system, and to help clarify their function and role in human disease.
- SKN-1 Regulation and Oxidative Stress Resistance in C. elegansThomas Blackwell; Fiscal Year: 2007..In the embryo, maternally provided SKN-1 initiates development of the feeding/digestive system. We have found that during postembryonic stages SKN-1 is expressed in the intestine and ASI chemosensory ..
- Neural Circuitry in the Caudal Solitary ComplexBret Smith; Fiscal Year: 2005..fibers of the vagus nerve from the digestive tract, neurons in the nucleus tractus solitarius (NTS) process digestive system information prior to further integration via higher brain areas and eventual activation of motor output to ..
- ION TRANSPORT MECHANISMS IN BLOOD CELLSPHILIP KNAUF; Fiscal Year: 2002..B3 and B3RP's are also important in epithelia, particularly those of the kidney and digestive system that are involved in secretion of acid or base...