Genomes and Genes
Summary: A small nodular mass of specialized muscle fibers located in the interatrial septum near the opening of the coronary sinus. It gives rise to the atrioventricular bundle of the conduction system of the heart.
Publications195 found, 100 shown here
- Prevention of ventricular desynchronization by permanent para-Hisian pacing after atrioventricular node ablation in chronic atrial fibrillation: a crossover, blinded, randomized study versus apical right ventricular pacingEraldo Occhetta
Divisione Clinicizzata di Cardiologia, , , Novara, Italy
J Am Coll Cardiol 47:1938-45. 2006..05 for both). CONCLUSIONS: Permanent para-Hisian pacing is feasible and safe. Compared with conventional right apical pacing, it allows an improvement in functional and hemodynamic parameters over long-term follow-up...
- Acidosis inhibits spontaneous activity and membrane currents in myocytes isolated from the rabbit atrioventricular nodeHongwei Cheng
Department of Physiology and Pharmacology, School of Medical Sciences, University of Bristol, Bristol, UK
J Mol Cell Cardiol 46:75-85. 2009..Little is currently known, however, about the effects of acidosis on the cellular electrophysiology of the atrioventricular node (AVN)...
- Randomized prospective trial of atrioventricular delay programming for cardiac resynchronization therapyNavinder S Sawhney
Cardiovascular Division, Washington University, School of Medicine, St. Louis, Missouri 63110, USA
Heart Rhythm 1:562-7. 2004..03) for group 1 vs group 2, respectively. CONCLUSIONS: Echocardiography-guided AV delay optimization using the aortic Doppler VTI improves clinical outcomes at 3 months compared to an empiric AV delay program of 120 ms...
- The Tbx2+ primary myocardium of the atrioventricular canal forms the atrioventricular node and the base of the left ventricleWim T J Aanhaanen
Heart Failure Research Center, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Circ Res 104:1267-74. 2009..The atrioventricular node, but not the atrioventricular bundle, was found to derive from Tbx2+ cells...
- Spontaneous frequency of rabbit atrioventricular node myocytes depends on SR functionJ M Ridley
Department of Physiology and Pharmacology, Cardiovascular Research Laboratories, Bristol Heart Institute, School of Medical Sciences, University of Bristol, Bristol BS8 1TD, UK
Cell Calcium 44:580-91. 2008..However, comparatively little is known about the role of intracellular Ca(2+) in the atrioventricular node (AVN)...
- An investigation of the role played by the E-4031-sensitive (rapid delayed rectifier) potassium current in isolated rabbit atrioventricular nodal and ventricular myocytesJ S Mitcheson
Department of Physiology, School of Medical Sciences, University of Bristol, UK
Pflugers Arch 438:843-50. 1999..It is concluded that IKr may participate in both AP repolarisation and the pacemaker depolarisation in AVN cells, whilst in ventricular myocytes, IKr and IK1 participate in controlling early and final AP repolarisation respectively...
- One-dimensional mathematical model of the atrioventricular node including atrio-nodal, nodal, and nodal-his cellsS Inada
University of Manchester, Manchester, United Kingdom
Biophys J 97:2117-27. 2009..action potential models have been developed for most regions of the heart, there is no model for the atrioventricular node (AVN). We have developed action potential models for single atrio-nodal, nodal, and nodal-His cells...
- Electrophysiological effects of ibutilide on the delayed rectifier K(+) current in rabbit sinoatrial and atrioventricular node cellsN Sato
Department of Physiology and Biophysics, The University of Calgary, Calgary, Alberta, Canada
Eur J Pharmacol 404:281-8. 2000....
- Determination of optimal atrioventricular delay for cardiac resynchronization therapy using acute non-invasive blood pressureZachary I Whinnett
International Centre for Circulatory Health, National Heart and Lung Institute, St Mary s Hospital and Imperial College, 5, 9 61 North Wharf Road, London W2 1LA, UK
Europace 8:358-66. 2006....
- Echocardiographic examination of atrioventricular and interventricular delay optimization in cardiac resynchronization therapyMaria Cristina Porciani
Division of Cardiology, Careggi Hospital, Florence, Italy
Am J Cardiol 95:1108-10. 2005..An additional improvement was obtained by tailored biventricular pacing. The optimal AVds were significantly shorter during right ventricular preactivation than during left ventricular preactivation...
- Rate-dependent AV delay optimization in cardiac resynchronization therapyChristoph Scharf
Division of Cardiology, University of Michigan, Ann Arbor, MI, USA
Pacing Clin Electrophysiol 28:279-84. 2005..During cardiac resynchronization therapy (CRT), cardiac performance is dependent on an optimized atrioventricular delay (AVD). However, the optimal AVD at different heart rates has not been defined yet during CRT...
- Characterization of the effects of ryanodine, TTX, E-4031 and 4-AP on the sinoatrial and atrioventricular nodesMohammed R Nikmaram
Department of Physiology, Iran University of Medical Sciences, Tehran, Iran
Prog Biophys Mol Biol 96:452-64. 2008..iNa), "rapidly activating" delayed rectifier K+ current (iKr) and ultrarapid delayed rectifier potassium current (IKur) on the pacemaker activity of the sinoatrial node (SAN) and the atrioventricular node (AVN) in the mouse.
- Ionic mechanisms of the effect of adenosine on single rabbit atrioventricular node myocytesA C Rankin
Department of Medical Cardiology, University of Glasgow, United Kingdom
Can J Cardiol 13:1183-7. 1997....
- Structure-function relationship in the AV junctionIgor R Efimov
Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA
Anat Rec A Discov Mol Cell Evol Biol 280:952-65. 2004In the normal heart, the atrioventricular node (AVN) is part of the sole pathway between the atria and ventricles. Under normal physiological conditions, the AVN controls appropriate frequency-dependent delay of contractions...
- Effects of acute systemic endothelin receptor blockade on cardiac electrophysiology in vivoAnna R M Gelzer
College of Veterinary Medicine, Cornell University, Ithaca, New York, USA
J Cardiovasc Pharmacol 44:564-70. 2004..However, antagonism of ET-1 by BQ-123 unmasks the effect of ET-1 on maintenance of vasomotor tone, which in turn may affect heart rate and sinus node automaticity in the intact pig...
- The atrioventricular node: origin, development, and genetic programMartijn L Bakker
Heart Failure Research Center, Academic Medical Center, Amsterdam, The Netherlands
Trends Cardiovasc Med 20:164-71. 2010..Within the axis, the atrioventricular node delays the impulse, allowing the ventricles to be filled before their contraction is initiated...
- Electrophysiologic effects of endothelin receptor-A blockade in patients with coronary artery diseaseTheofilos M Kolettis
University of Ioannina, 1 University Street, 45 110 Ioannina, Greece
J Interv Card Electrophysiol 8:173-9. 2003..We examined the effects of acute endothelin receptor-A blockade on the sinus node, the atrioventricular node and on the ventricular myocardium, in patients with single-vessel coronary artery disease and preserved ..
- Morphological and electrophysiological properties of single myocardial cells from Koch triangle of rabbit heartFu-xian Ren
Department of Cardiology, Second Hospital, Xi'an Jiaotong University, Xi'an 710004, China
Chin Med J (Engl) 119:2075-84. 2006..In view of the prominent percentage and electrical properties, tiny spindle and slender spindle cells were presumed to play important roles...
- Localization of Na+ channel isoforms at the atrioventricular junction and atrioventricular node in the ratShin Yoo
Cardiovascular Research Group, School of Medicine, University of Manchester, Core Technology Facility, 46 Grafton St, Manchester M13 9NT, United Kingdom
Circulation 114:1360-71. 2006The electrical activity of the atrioventricular node (AVN) is functionally heterogeneous, but how this relates to distinct cell types and the 3-dimensional structure of the AVN is unknown...
- Computer three-dimensional reconstruction of the atrioventricular nodeJue Li
Cardiovascular Research Group, Faculty of Medical and Human Sciences, University of Manchester, Core Technology Facility, 46 Grafton St, Manchester M13 9NT, United Kingdom
Circ Res 102:975-85. 2008Because of its complexity, the atrioventricular node (AVN), remains 1 of the least understood regions of the heart. The aim of the study was to construct a detailed anatomic model of the AVN and relate it to AVN function...
- Inhibition of spontaneous activity of rabbit atrioventricular node cells by KB-R7943 and inhibitors of sarcoplasmic reticulum Ca(2+) ATPaseHongwei Cheng
School of Physiology and Pharmacology, Medical Sciences Building, University of Bristol, UK
Cell Calcium 49:56-65. 2011The atrioventricular node (AVN) can act as a subsidiary cardiac pacemaker if the sinoatrial node fails...
- Effects of cavotricuspid isthmus ablation on atrioventricular node electrophysiology in patients with typical atrial flutterC T Tai
Division of Cardiology, Department of Medicine, Cardiovascular Research Center, National Yang Ming University School of Medicine, and Taipei Veterans General Hospital, Taipei, Taiwan, ROC
Circulation 104:1501-5. 2001..The atrial musculature in the cavotricuspid isthmus is a part of posterior inputs to the AV node. In patients with typical atrial flutter, effects of radiofrequency ablation of this isthmus on AV node conduction are still unknown...
- Measurement precision in the optimization of cardiac resynchronization therapyRobert G Turcott
Division of Cardiovascular Medicine and Center for Biomedical Informatics Research, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
Circ Heart Fail 3:395-404. 2010..A variety of techniques are used to estimate optimum AV/VV intervals; however, the precision of their estimates and the ramifications of an imprecise estimate have not been characterized previously...
- New onset postural orthostatic tachycardia syndrome following ablation of AV node reentrant tachycardiaKhalil Kanjwal
Division of Cardiology, Department of Medicine, Health Sciences Campus, The University of Toledo Medical Center, Mail Stop 1118, 3000 Arlington Ave, Toledo, OH, 43614, USA
J Interv Card Electrophysiol 29:53-6. 2010..as inappropriate sinus tachycardia has been reported to occur following slow pathway ablation for atrioventricular node tachycardia...
- Long-term outcome of single-chamber atrial pacing compared with dual-chamber pacing in patients with sinus-node dysfunction and intact atrioventricular node conductionWon Ho Kim
Division of Cardiology, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea
Yonsei Med J 51:832-7. 2010..The optimal pacing mode with either single chamber atrial pacemaker (AAI or AAIR) or dual chamber pacemaker (DDD or DDDR) is still not clear in sinus-node dysfunction (SND) and intact atrioventricular (AV) conduction...
- Right ventricular pacing can induce ventricular dyssynchrony in patients with atrial fibrillation after atrioventricular node ablationLaurens F Tops
Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
J Am Coll Cardiol 48:1642-8. 2006..The development of LV dyssynchrony was associated with deterioration in heart failure symptoms, systolic LV function, and LV dilatation...
- Atrioventricular node ablation and permanent ventricular pacemaker implantation without fluoroscopy: use of an electroanatomic navigation systemRicardo Ruiz-Granell
Arrhythmia Unit, Department of Cardiology, Hospital Clinico Universitario, Valencia, Spain
J Cardiovasc Electrophysiol 16:793-5. 2005..This case illustrates the stand-alone use of one of the new non-fluoroscopic navigation systems for a complete procedure such as AV ablation and pacemaker implantation...
- Correlation of echo-Doppler optimization of atrioventricular delay in cardiac resynchronization therapy with invasive hemodynamics in patients with heart failure secondary to ischemic or idiopathic dilated cardiomyopathyAnnemieke H M Jansen
Department of Cardiology, Catharina Hospital, Eindhoven, The Netherlands
Am J Cardiol 97:552-7. 2006..The measurement of the maximal VTI of mitral inflow is the most accurate method...
- Diversity of connexin expression patterns in the atrioventricular node: vestigial consequence or functional specialization?Steven R Coppen
National Heart and Lung Institute, Faculty of Medicine, Imperial College, London, United Kingdom
J Cardiovasc Electrophysiol 13:625-6. 2002
- Successful catheter ablation of atrial tachycardia originating near the atrioventricular node from the noncoronary sinus of ValsalvaHiroshi Tada
Division of Cardiology, Gunma Prefectural Cardiovascular Center, Maebashi, Gunma, Japan
Pacing Clin Electrophysiol 27:1440-3. 2004..Complete elimination of the tachycardia was achieved with RF energy application from this site...
- High resistance of atrioventricular node to cryoablation: a great safety margin targeting perinodal arrhythmic substratesNicasio Perez-Castellano
Unit of Arrhythmias, Cardiovascular Institute, San Carlos University Hospital, Madrid, Spain
Heart Rhythm 3:1189-95. 2006..Findings from animal studies and small series of patients support the greater safety of cryoenergy over radiofrequency in the ablation of arrhythmic substrates near the AV node...
- Right and left inferior extensions of the atrioventricular node may represent the anatomic substrate of the slow pathway in humansDemosthenes G Katritsis
Department of Cardiology, Athens Euroclinic, Greece
Heart Rhythm 1:582-6. 2004..The purpose of this study was to investigate the electrophysiologic characteristics of the inferior extensions of the human atrioventricular (AV) node and their possible relationship to slow pathway conduction...
- Long-term survival after ablation of the atrioventricular node and implantation of a permanent pacemaker in patients with atrial fibrillationC Ozcan
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
N Engl J Med 344:1043-51. 2001..In patients with atrial fibrillation that is refractory to drug therapy, radio-frequency ablation of the atrioventricular node and implantation of a permanent pacemaker are an alternative therapeutic approach...
- Cx43 and dual-pathway electrophysiology of the atrioventricular node and atrioventricular nodal reentryVladimir P Nikolski
Dept of Biomedical Engineering, Case Western Reserve University, 10900 Euclid Ave, Cleveland, Ohio 44106-7207, USA
Circ Res 92:469-75. 2003..Immunolabeling revealed that the FP and SP are formed by Cx43-expressing bundles surrounded by tissue without Cx43. Cx43-expressing posterior nodal extensions are the substrate of AVNR during both intranodal and extranodal reentry...
- Connexin30.2 containing gap junction channels decelerate impulse propagation through the atrioventricular nodeMaria M Kreuzberg
Institut fur Genetik, Abteilung Molekulargenetik, Universitat Bonn, Romerstrasse 164, 53117 Bonn, Germany
Proc Natl Acad Sci U S A 103:5959-64. 2006..g., atrial fibrillation) by preventing rapid conduction to the ventricles potentially associated with hemodynamic deterioration...
- Significant effects of atrioventricular node ablation and pacemaker implantation on left ventricular function and long-term survival in patients with atrial fibrillation and left ventricular dysfunctionCevher Ozcan
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
Am J Cardiol 92:33-7. 2003Control of ventricular rate by atrioventricular node ablation and pacemaker implantation in patients with drug-refractory atrial fibrillation (AF) is associated with improved left ventricular (LV) function...
- Impact of transforming growth factor-beta1 on atrioventricular node conduction modification by injected autologous fibroblasts in the canine heartT Jared Bunch
Division of Cardiovascular Disease, Department of Internal Medicine, Mayo Clinic, Rochester, MN 55902, USA
Circulation 113:2485-94. 2006..The effect on AV node conduction is substantially enhanced by pretreatment of fibroblasts with TGF-beta1. These data have therapeutic potential for the management of rapid ventricular rate during AF without pacemaker implantation...
- Echocardiographic modeling of cardiac dyssynchrony before and during multisite stimulation: a prospective studyS Cazeau
Clinique Bizet, Paris
Pacing Clin Electrophysiol 26:137-43. 2003..EDP measurements appear to identify potential candidates for CRT, and to confirm the success of system implantation...
- Specific pattern of ionic channel gene expression associated with pacemaker activity in the mouse heartCeline Marionneau
l institut du thorax, INSERM U533, Faculte de Medecine, 44035 Nantes Cedex, France
J Physiol 562:223-34. 2005..large-scale real-time RT-PCR, we have profiled 71 channels and related genes in the sinoatrial node (SAN), atrioventricular node (AVN), the atria (A) and ventricles (V)...
- Cardiac resynchronization therapy: Part 2--issues during and after device implantation and unresolved questionsJeroen J Bax
Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
J Am Coll Cardiol 46:2168-82. 2005..Finally, open questions concerning when to combine CRT with implantable cardioverter-defibrillator therapy and the cost-effectiveness of CRT are discussed...
- Clinical, genetic, and biophysical characterization of SCN5A mutations associated with atrioventricular conduction blockDao W Wang
Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tenn, and Department of Pediatrics, Medical University of South Carolina, Charleston, USA
Circulation 105:341-6. 2002..The mutations also reduce sodium current density and enhance slower inactivation components. Action potential simulations predict that this combination of biophysical abnormalities will significantly slow myocardial conduction velocity...
- Cystic tumor of the atrioventricular nodal regionYuichiro Kaminishi
Department of Cardiovascular Surgery, Hitachi General Hospital, 2-1-1 Jonan-cho, Hitachi, Ibaraki 317-0077, Japan
Jpn J Thorac Cardiovasc Surg 50:37-9. 2002..The histopathological findings confirmed the lesion as a cystic tumor of the atrioventricular nodal region. This is the third known case of this condition diagnosed antemortem and treated successfully with surgical excision...
- Transvenous catheter ice mapping and cryoablation of the atrioventricular node in dogsM Dubuc
Department of Medicine, Montreal Heart Institute, Quebec, Canada
Pacing Clin Electrophysiol 22:1488-98. 1999..Ablation of the AV node is effective with a double freeze-thaw cycle using a percutaneous catheter cryoablation system. Ice mapping of the area allows for identification of the targeted site...
- [Congenital atrioventricular block and maternal lupus erythematosus. Histologic discovery of tumor of the atrioventricular node]F Fontaliran
Service de cardiologie, , Paris
Arch Mal Coeur Vaiss 82:609-13. 1989..In addition, a tumour of the atrioventricular node, known as mesothelioma or hemolymphangioma, was discovered...
- Reduced cardiac conduction velocity and predisposition to arrhythmias in connexin40-deficient miceS Kirchhoff
Institut für Genetik Abt Molekulargenetik, Universitat Bonn, Römerstr 164, 53117, Bonn, Germany
Curr Biol 8:299-302. 1998..As the distribution of Cx40 protein is similar in mouse and human hearts, further functional analysis of Cx40 should yield relevant insights into arrhythmogenesis in human patients...
- [Influence of the autonomic nervous system on the normal and pathological atrioventricular node]J Victor
Service de cardiologie, CHR, Angers
Arch Mal Coeur Vaiss 80:1471-7. 1987..This sympathetic overdrive was also found to be present in the sinus node...
- "Nodoventricular" accessory pathway: evidence for a distinct accessory atrioventricular pathway with atrioventricular node-like propertiesG J Klein
Department of Medicine, University of Western Ontario, London, Canada
J Am Coll Cardiol 11:1035-40. 1988..These data suggest that a "typical" nodoventricular pathway, by electrophysiologic criteria, may in fact be an AV pathway with AV node-like conduction properties and a distal right ventricular insertion site...
- Cryoablation outcomes for AV nodal reentrant tachycardia comparing 4-mm versus 6-mm electrode-tip cathetersLena Rivard
Electrophysiology Service, Montreal Heart Institute, Montreal, Quebec, Canada
Heart Rhythm 5:230-4. 2008..Cryoablation is increasingly used to treat atrioventricular nodal reentrant tachycardia (AVNRT). It is unknown whether larger electrode-tip cryocatheters improve outcomes without compromising safety...
- Cardiovascular magnetics resonance diagnosis of cystic tumor of the atrioventricular nodeThao T Tran
Huntington Medical Research Institutes, Pasadena, CA, USA
J Cardiovasc Magn Reson 11:13. 2009..LGE CMR is also useful for identifying the nature of cardiac masses or lesions. We report a case of a rare primary cystic tumor of the atrioventricular node, in which CMR proved to be valuable.
- Catheter cryoablation of the atrioventricular node in patients with atrial fibrillation: a novel technology for ablation of cardiac arrhythmiasM Dubuc
Research Center, Montreal Heart Institute, Quebec, Canada
J Cardiovasc Electrophysiol 12:439-44. 2001..The studies also showed that reversible "ice mapping" can be performed before creating permanent lesions. We investigated the feasibility and safety of applying this new technology in man...
- Change in the retrograde atrial activation sequence following radiofrequency modification of the atrioventricular node: implications for the electrophysiologic circuit of a variant of atrioventricular nodal reentrant tachycardiaJose Dizon
Division of Cardiology, Presbyterian Hospital, Columbia University, New York, New York, USA
J Cardiovasc Electrophysiol 14:461-6. 2003....
- Imaging the heart: computer 3-dimensional anatomic models of the heartMark R Boyett
Division of Cardiovascular and Endocrine Sciences, University of Manchester, M13 9XX Manchester, UK
J Electrocardiol 38:113-20. 2005..However, already the two types of model are beginning to be used in tandem to reconstruct the activation sequence of the heart both during sinus rhythm and arrhythmias...
- Three-dimensional reconstruction of the rabbit atrioventricular conduction axis by combining histological, desmin, and connexin mapping dataYu Shien Ko
First Cardiovascular Division, Chang Gung Memorial Hospital, Taipei, Taiwan, Republic of China
Circulation 109:1172-9. 2004....
- Doppler index and plasma level of atrial natriuretic hormone are improved by optimizing atrioventricular delay in atrioventricular block patients with implanted DDD pacemakersN Toda
Second Department of Internal Medicine Yokohama City University School of Medicine, Yokohama, Japan
Pacing Clin Electrophysiol 24:1660-3. 2001..This study shows the importance of the optimal AV delay setting in patients with an implanted DDD pacemaker, the Doppler index and plasma ANP levels are good indicators for optimizing AV delay...
- Long-term follow-up of atrioventricular delay optimization in patients with biventricular pacingNoriko Inoue
Second Department of Internal Medicine, Yokohama City University Hospital, Japan
Circ J 69:201-4. 2005..6+/-0.5 to 1.4+/-0.5 (p<0.001). CONCLUSIONS: AV delay optimization is important in patients with biventricular pacing and can be easily achieved by the new method...
- Cryoablation of focal atrial tachycardia originating close to the atrioventricular nodeTom Wong
St. Mary's Hospital and Imperial College, London, United Kingdom
J Cardiovasc Electrophysiol 15:838. 2004
- Partial atrioventricular canal defect with inverted atrioventricular nodal input into an inferiorly displaced atrioventricular nodePaul Khairy
Electrophysiology Service and Adult Congenital Heart Center, Montreal Heart Institute, Montreal, Quebec, Canada
Heart Rhythm 4:355-8. 2007
- Accessory atrioventricular node with properties of a typical accessory pathway: anatomic-electrophysiologic correlationM H Gollob
Department of Medicine, Section of Cardiology, Baylor College of Medicine, Houston, Texas 77030, USA
J Cardiovasc Electrophysiol 11:922-6. 2000..No typical AV accessory pathway was found. This is the first report of an accessory AV node that participated in AVRT. It was deeper than typical radiofrequency catheter ablation lesions...
- Atrioventricular node modification in patients with chronic atrial fibrillation: role of morphology of RR interval variationS Rokas
Interventional Cardiology Unit, Department of Clinical Therapeutics, Alexandra Hospital, Athens University Medical School, Athens, Greece
Circulation 103:2942-8. 2001....
- Successful selective ablation of fast atrioventricular node pathway by cryothermal energy applicationRoberto De Ponti
Department of Cardiovascular Sciences, Ospedale di Circolo e Fondazione Macchi University of Insubria, Varese, Italy
Pacing Clin Electrophysiol 27:1170-1. 2004..Slow formation of a permanent lesion by cryothermal energy application allowed precise modulation of atrioventricular nodal conduction until the endpoints of complete fast pathway ablation were met with long-term cure of the arrhythmia...
- Para-Hisian pacing: useful clinical technique to differentiate retrograde conduction between accessory atrioventricular pathways and atrioventricular nodal pathwaysHiroshi Nakagawa
Cardiac Arrhythmia Research Institute, Department of Medicine University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
Heart Rhythm 2:667-72. 2005
- Radiofrequency catheter ablation of accessory pathways during pre-excited atrial fibrillation: acute success rate and long-term clinical follow-up results as compared to those patients undergoing successful catheter ablation during sinus rhythmSedat Kose
Department of Cardiology, Gulhane Military Medical Academy, 06018, Etlik, Ankara, Turkey
Heart Vessels 20:142-6. 2005....
- Stability of ventricular repolarization in conscious dogs with chronic atrioventricular dissociation and his-bundle pacingRob Sanders
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, E. Lansing, Michigan 48824, USA
Pacing Clin Electrophysiol 27:1475-83. 2004..This conscious HIS-pacing model in dogs is a sensitive, stable, and reproducible method to define ventricular repolarization characteristics over a range of programmable HRs and experimental conditions...
- Wide QRS-complex tachycardia with variable VA-conduction: what is the mechanism?Hildegard Tanner
Swiss Cardiovascular Center Bern, University Hospital, CH 3010 Bern, Switzerland
Europace 10:110-1. 2008..detailed mapping showed cranial to caudal depolarization of the His bundle, leading to the diagnosis of atrioventricular node re-entrant tachycardia...
- Evaluation of pacemaker dependence in patients on ablate and pace therapy for atrial fibrillationEraldo Occhetta
Cardiology Division, Azienda Ospedaliera Maggiore della Carita, Corso Mazzini 18, 28100 Novara, Italy
Europace 9:1119-23. 2007..The aim of our study was to evaluate the PM dependence and the incidence of correlated clinical phenomena in a patients population with AV block induced by RF ablation of the AV junction...
- Congenital complete atrioventricular block and preexcitation syndrome: a well-matched partnerJose Amador Rubio
Cardiology Unit, Fundación Hospital Alcorcón Madrid, Spain
J Interv Card Electrophysiol 13:159-61. 2005..The AP was located on the left side and posterior. The absence of retrograde conduction through the AP and also a long conduction time were demonstrated...
- [The treatment of atrial fibrillation at the time of catheter ablation--editorial]R Labrova
Vnitr Lek 53:923-4. 2007
- Right atrial electrical isolation: left atrial connection to the atrioventricular nodeFlorin T Deger
Temple University Hospital, Department of Medicine, Division of Cardiology, Philadelphia, Pennsylvania 19140, USA
Heart Rhythm 2:643-5. 2005
- The effects of dexmedetomidine on cardiac electrophysiology in childrenGregory B Hammer
Department of Anesthesiology, Lucile Packard Children s Hospital and Stanford University School of Medicine, Stanford, California, USA
Anesth Analg 106:79-83, table of contents. 2008..No data regarding the effects of DEX on the cardiac conduction system are available. We therefore aimed to characterize the effects of DEX on cardiac conduction in pediatric patients...
- Correction of QT values to allow for increases in heart rate in conscious Beagle dogs in toxicology assessmentMarshall Leslie Tattersall
Experimental Medicine, AstraZeneca R and D, Charnwood, Loughborough, Leicestershrie LE11 5RH, UK
J Pharmacol Toxicol Methods 53:11-9. 2006..DISCUSSION: Overall, the data suggest that an evaluation of the most appropriate correction factor should be applied to each laboratory using their own data collected by their own method in their particular strain of dog...
- Comparison of electropharmacological effects of bepridil and sotalol in halothane-anesthetized dogsTomomichi Ishizaka
Department of Pharmacology, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Chuo, Japan
Circ J 72:1003-11. 2008..In this study, the electro-pharmacological effects of bepridil were compared with those of dl-sotalol, a representative class III antiarrhythmic drug, using the halothane-anesthetized canine model...
- Selective atrionodal input ablation for induction of proximal complete heart block with stable junctional escape rhythm in patients with uncontrolled atrial fibrillationBernhard Strohmer
Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center and UCLA School of Medicine, Los Angeles, CA, USA
J Interv Card Electrophysiol 8:49-57. 2003..The study tests the hypothesis that ablating all inputs to the atrioventricular (AV) node can result in complete heart block with stable junctional escape rhythm...
- Electrocardiographic and electrophysiologic characteristics of anteroseptal, midseptal, and posteroseptal accessory pathwaysMajid Haghjoo
Department of Pacemaker and Electrophysiology, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
Heart Rhythm 4:1411-9. 2007..Approximately 30% of all accessory pathways (APs) are located in the septal area, and understanding the electrocardiographic and electrophysiologic of these APs is crucial for safe and effective ablation of these pathways...
- Delineation of AV conduction pathways by selective surgical transection: effects on antegrade and retrograde transmissionEugene Patterson
Health Sciences Center and Department of Veterans Affairs Medical Center, University of Oklahoma, Oklahoma City, OK 73104, USA
J Interv Card Electrophysiol 13:95-105. 2005..The role for transitional cells as determinants of AH and HA conduction was examined in the superfused rabbit AV junction...
- Atypical atrioventricular nodal reentry with eccentric atrial activation. Is the right target on the left?Miguel Valderrabano
Heart Rhythm 4:433-4. 2007
- Atypical atrioventricular nodal reentrant tachycardia with eccentric coronary sinus activation: electrophysiological characteristics and essential effects of left-sided ablation inside the coronary sinusKiyoshi Otomo
Division of Cardiology, Cardiovascular Center, Tsuchiura Kyodo Hospital, Tsuchiura, Japan
Heart Rhythm 4:421-32. 2007..The precise electrophysiological characteristics and essential effects of left-sided ablation in atrioventricular nodal reentrant tachycardia (AVNRT) with eccentric coronary sinus (CS) activation (ECSA) have not been described...
- Unique electrophysiologic characteristics of atrioventricular nodal reentrant tachycardia with different ventriculoatrial block patterns: effects of slow pathway ablation and insights into the location of the reentrant circuitKiyoshi Otomo
Division of Cardiology, National Cardiovascular Center, Suita, Japan
Heart Rhythm 3:544-54. 2006..The electrophysiologic mechanisms of different ventriculoatrial (VA) block patterns during atrioventricular nodal reentrant tachycardia (AVNRT) are poorly understood...
- Pacing site and bradycardia dependent retrograde conduction block over an atrioventricular accessory pathwayRong Bai
Department of Cardiovascular Science, Ospedale di Circolo e Fondazione Macchi, University of Insubria-Varese, Varese, Italy
Europace 8:438-42. 2006....
- Spontaneous high degree atrioventricular block during AV nodal re-entrant tachycardiaBabak Kazemi
Department of Pacemaker and Electrophysiology, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Mellat Park, Vali e Asr Avenue, P O Box 15745 1341, Tehran 1996911151, Iran
Europace 8:421-2. 2006..Electrophysiological manoeuvres identified the site of block in the lower common pathway of the AV node. This arrhythmia was rendered non-inducible after slow pathway ablation...
- [Usefulness of incremental atrial pacing for evaluating the effectiveness of the ablation of the slow perinodal pathway]Juan Martinez-Sanchez
Servicio de Cardiologia, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain
Rev Esp Cardiol 60:32-7. 2007..To study the usefulness of incremental atrial pacing for evaluating the effect of radiofrequency catheter ablation on slow pathway conduction in patients with atrioventricular (AV) nodal reentrant tachycardia...
- Clinical implications of "pure" Hisian pacing in addition to para-Hisian pacing for the diagnosis of supraventricular tachycardiaSeiji Takatsuki
Lariboisiere University Hospital, Paris, France
Heart Rhythm 3:1412-8. 2006..of differentiating between pathways for retrograde conduction over the accessory pathway (AP) and over the atrioventricular node (AVN)...
- [Uni-directional atrioventricular block]Maciej Swiatkowski
Klinika Kardiologii CMKP, , 04-073 Warszawa, Poland
Kardiol Pol 64:749-52; discussion 753. 2006
- Atrial activation during atrioventricular nodal reentrant tachycardia: studies on retrograde fast pathway conductionDemosthenes G Katritsis
Department of Cardiology, Athens Euroclinic, Athens, Greece
Heart Rhythm 3:993-1000. 2006....
- A NavX-guided ablation of a nodo-fascicular fibreChristopher Reithmann
Medizinische Klinik I, Klinikum Grosshadern, Universitat Munchen, Marchioninstr 15, Munich, Germany
Europace 9:424-5. 2007..5-2 cm away from the tricuspid annulus in a three-dimensional reconstruction of the right atrium and right ventricle...
- Fasciculoventricular bypass tract with decremental conduction propertiesSujoya Dey
University of Michigan Medical Center, Ann Arbor, 48109, USA
Heart Rhythm 3:975-6. 2006
- Effect of slow pathway ablation in atrioventricular nodal reentrant tachycardia on the electrophysiologic characteristics of the inferior atrial inputs to the human atrioventricular nodeDemosthenes G Katritsis
Department of Cardiology, Athens Euroclinic, Greece
Am J Cardiol 97:860-5. 2006....
- [Enhanced atrioventricular nodal conduction]Kaoru Sugi
Division of Cardiovascular Medicine, Toho University, Ohashi Medical Center
Nippon Rinsho . 2007
- The atrioventricular nodal reentrant tachycardia circuit: a proposalDemosthenes G Katritsis
Department of Cardiology, Athens Euroclinic, 9 Athanassiadou Street, Athens 11521, Greece
Heart Rhythm 4:1354-60. 2007..In the present article, we summarize the available evidence and propose a comprehensive model of the tachycardia circuit for all forms of atrioventricular nodal reentrant tachycardia based on the concept of atrionodal inputs...
- A unipolar coronary sinus mapping study of patients with left-sided atrioventricular accessory pathwaysSatoko Kubota
Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
Int Heart J 46:657-67. 2005..In conclusion, the site-dependent variations of the unipolar CS atrial electrogram underlie the limited usefulness of the 'PQS pattern' in left posteroseptal accessory pathway localization...
- Complete AV block developing in a patient with manifest ventricular preexcitationYasuhiro Takagi
Division of Cardiovascular Medicine, Department of Medicine, Nihon University School of Medicine, Tokyo 173-8610, Japan
Int Heart J 46:729-35. 2005..This patient developed HV block by atrial extrastimulus (S1S1: 600 msec, S1S2 <or= 350 msec). Thus, the patient was diagnosed as having combined atriofascicular and fasciculoventricular connections...
- Incidence and mechanism of dislocated fast pathway in various forms of atrioventricular nodal reentrant tachycardiaYasuaki Tanaka
Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
Circ J 71:1099-106. 2007..The incidence and mechanism of the dislocated antegrade fast pathway (A-FP) were examined in various forms of atrioventricular nodal reentrant tachycardia (AVNRT)...
- A novel predictive pharmacokinetic/pharmacodynamic model of repolarization prolongation derived from the effects of terfenadine, cisapride and E-4031 in the conscious chronic av node--ablated, His bundle-paced dogEmily R Nolan
Pfizer Global Research and Development, Ann Arbor, MI 48105, USA
J Pharmacol Toxicol Methods 53:1-10. 2006..prolong ventricular repolarization, were selected to evaluate the sensitivity of the conscious chronic atrioventricular node--ablated, His bundle-paced Dog for defining drug induced cardiac repolarization prolongation...
- Participation of a concealed atriohisian tract in the reentrant circuit of the slow-fast type of atrioventricular nodal reentrant tachycardiaKiyoshi Otomo
Division of Cardiology, National Cardiovascular Center, Suita, Japan
Heart Rhythm 4:703-10. 2007..The retrograde fast pathway in typical atrioventricular nodal reentrant tachycardia (AVNRT) exhibits marked variation in its electrophysiologic properties...
- Pacing delivered rate and rhythm control for atrial fibrillationDamian Paul Redfearn
Division of Cardiology, University of Western Ontario, London, Ontario, Canada
Curr Opin Cardiol 21:83-7. 2006..Patients with sinus node dysfunction should be paced in the atrium alone. There is no indication for use of a device for atrial fibrillation without a conventional indication for pacing...
- Sinus node function in children with congenital complete atrioventricular blockGertie C M Beaufort Krol
Beatrix Children s Hospital, Division of Pediatric Cardiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9700 RB, Groningen, The Netherlands
Europace 9:844-7. 2007..In these children, it may be preferable to use single-lead VDD pacing, but for VDD pacing a normal sinus node function is required. Our aim was to study sinus node function in children with CCAVB...
- [Symptomatic recurrent bradycardia--always an indication for pacemaker implantation? The role of RF ablation for incessant focal tachycardia from AV node region and advanced AV nodal block]Maria Miszczak-Knecht
Klinika Kardiologii, Instytut Pomnik Centrum Zdrowia Dziecka, Al Dzieci Polskich 20, 04 730 Warszawa
Kardiol Pol 64:1316-20. 2006..Successful ablation of atrial tachycardia revealed that SA and AV node properties were in the normal range; therefore no pacemaker implantation was needed...
- Demonstration of a left atrial input to the atrioventricular node in humansMario D Gonzalez
Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, FL 32610 0277, USA
Circulation 106:2930-4. 2002..During right atrial stimulation, the anterior and posterior approaches provide inputs to the atrioventricular (AV) node. The purpose of the present study was to determine how activation proceeding from the left atrium reaches the AV node...
- Paced QT dispersion and QT morphology after radiofrequency atrioventricular junction ablation: impact of left ventricular functionSatish R Raj
Division of Cardiology, Foothills Medical Center and the Cardiovascular Disease Research Group, University of Calgary, Calgary, Alberta, Canada
Pacing Clin Electrophysiol 26:662-8. 2003..02) function groups. Following AVJ ablation, QTdisp increased during a sudden rate drop in patients with reduced LV function, but not in patients with normal LV function...
- Radiofrequency ablation of atrioventricular accessory pathways associated with discordant atrioventricular connectionsPedro Iturralde
Department of Electrophysiology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
Cardiol Young 12:542-8. 2002..6 months. No complications were observed during the procedures. We conclude that radiofrequency ablation is feasible and effective in the ablation of accessory pathways in patients with discordant atrioventricular connections...
- Usefulness of a non-invasive scoring system in predicting the outcome of electrophysiologic studies in non-invasively unexplained syncopeK Seidl
Herzzentrum Ludwigshafen, Kardiologie, Bremserstr 79, 67063 Ludwigshafen, Germany
Z Kardiol 92:147-54. 2003..However, it is invasive with possible procedure-related complications. Therefore, it would be helpful to identify patients in whom an electrophysiologic study is useful for diagnosis of syncope...
- [Management of nodal reentrant tachycardia with radiofrequency: predictive criteria of success]P Jais
Service de cardiologie, Hopital Cardiologique du Haut Leveque, Pessac
Arch Mal Coeur Vaiss 88:1849-54. 1995..In addition, ablation should be started when the catheter is radiologically stable and should not be interrupted in the absence of a junctional rhythm...
- TRANSMURAL DEFORMATIONJames Covell; Fiscal Year: 1993..of the left ventricle, initiated from the atrium and traveling through the His-Purkinje system via the atrioventricular node, provides for relatively synchronous activation of ventricular muscle...
- STRUCTURE/FUNCTION RELATIONSHIP OF THE AV NODEIgor Efimov; Fiscal Year: 2002..advances in the treatment of supraventricular arrhythmias, the mechanisms governing conduction through the atrioventricular node (AV) remain poorly understood...
- Catheter Guidance System for RF Ablation of ArrhythmiasGordon Hirschman; Fiscal Year: 2007..This work will serve as the foundation for development and in-vivo test of a full prototype guidance system in Phase II. ..
- High-Speed, Depth-Resolved Images of Cardiac physiologyGuy Salama; Fiscal Year: 2007..We focus here on the heart because therein lie salient problems that are ready to be addressed by this new technology. However, the wide range of possible applications may lead to the commercialization of this new technology. ..
- Focal Modification of Electrical Conduction in the HeartJ Donahue; Fiscal Year: 2006..As an initial attempt to investigate this theory, we will focus on the atrioventricular node, an anatomically well-defined region where functional changes are easily observed...
- REENTRANT ACTIVITY IN CULTURED CARDIAC CELL MONOLAYERSLeslie Tung; Fiscal Year: 2004..primary role in many types of arrhythmias, including tachycardia and flutter in the atria, ventricles, and atrioventricular node. Reentry may involve anatomical pathways, or it may be functional, with leading circle, figure-eight, ..
- MODIFICATION OF AV NODE FUNCTION IN ATRIAL FIBRILLATIONTodor Mazgalev; Fiscal Year: 2003..This would benefit patients with pharmacologically resistant or surgically inappropriate treatment of the disease. ..
- Towards a Non-Invasive Therapy for Atrial FibrillationBenjamin Scherlag; Fiscal Year: 2004..This new therapeutic approach could be utilized as a non-invasive application or incorporated into an implantable device for treatment of patients with PAF. ..
- Real-time control system for biological experimentsDavid J Christini; Fiscal Year: 2010....
- Predictive multiscale modeling of atrial fibrillation for therapy developmentDAVID J contact CHRISTINI; Fiscal Year: 2010..The overall goal of this project is to develop such a multiscale modeling framework, which will enable the evaluation of potential pharmacological and device-based atrial fibrillation therapies. ..
- Mechanisms of Cardiac AlternansDavid J Christini; Fiscal Year: 2010..By doing so, the proposed work may help improve our understanding of how alternans may trigger cardiac arrhythmias. ..
- Real-time control system for biological experimentsDavid J Christini; Fiscal Year: 2010....
- Real-time control system for biological experimentsDAVID CHRISTINI; Fiscal Year: 2007..6. To optimize ease of use. To minimize the barrier of entry for beginners and maximize the productivity of experienced users, we will emphasize user-friendliness and develop comprehensive documentation. ..
- Genetic Predictors of QT Response During ExercisePrince Kannankeril; Fiscal Year: 2007..This research has the potential to permit identification of individuals at risk for sudden cardiac death and therefore has significant relevance to public health. (End of Abstract) ..
- Fatty Acids and Major Cardiovascular OutcomesDariush Mozaffarian; Fiscal Year: 2009....
- Mercury, Selenium, and Risk of Cardiovascular Disease in Women and MenDariush Mozaffarian; Fiscal Year: 2010....
- Mercury, Selenium and Risk of Cardiovascular Disease in Women and MenDariush Mozaffarian; Fiscal Year: 2009....
- Consequences of AF: sympathetic activity and ventricular repolarizationMohamed Hamdan; Fiscal Year: 2007..The results of our studies could explain the increased mortality associated with AF and should have a great impact on our management of patients with AF and heart failure. ..
- Fatty Acids and Cardiovascular HealthDariush Mozaffarian; Fiscal Year: 2007..End of Abstract) ..
- PHYSIOLOGIC BENEFITS OF BIVENTRICULAR PACING IN CHFMohamed Hamdan; Fiscal Year: 2002..Similarly, a reduction in inducibility of ventricular arrhythmias, if present with long term pacing, may have an impact on the survival and on our management of patients with implantable defibrillators and frequent shocks. ..
- Fatty Acids and Major Cardiovascular OutcomesDariush Mozaffarian; Fiscal Year: 2007....
- Emerin functions in transcriptional regulationJames Holaska; Fiscal Year: 2004..The initial characterization of these interactions will serve as the foundation for studying the role of the nuclear envelope in transcriptional regulation in my own laboratory. ..
- Image-guided Fetal Cardiac InterventionJohn Triedman; Fiscal Year: 2005..abstract_text> ..
- Mercury, Selenium, and Risk of Cardiovascular Disease in Women and MenDariush Mozaffarian; Fiscal Year: 2007....