tibial arteries

..Despite the moderate patency rates after one year, SA may serve as a "temporary bypass" to provide wound healing and limb salvage...

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..We advocate that these anatomical features contribute to clinical applications of the IMS flap. It may be useful for reconstruction of the lower leg and heel as safer options with less morbidity...

..these alternative conduits have not resulted in equivalent results when used for distal bypass to tibial arteries. Several authors have reported upon the use of venous tissue at the distal anastomosis in the form of cuffs, ..

..This technique might offer new opportunities for patients with non-healing ulcers which are technically and/or medically inoperable...

..02), but neither survival nor amputation rates were significantly different. CONCLUSIONS: Subintimal angioplasty is a safe and effective procedure for treating isolated crural vessels in patients with severe lower limb ischemia...

..To evaluate the feasibility and the mid-term results of subintimal angioplasty (SA) in the treatment of critical limb ischaemia (CLI) with tibial vessels occlusions...

..5 cm) of femoro-popliteal or tibial arteries, for SA...

..a 10 x 16 cm soft tissue defect of right lower leg that accompanied with occluded anterior and posterior tibial arteries in a 30-year-old man who sustained comminuted type III(B) Gustilo open tibial and fibular fracture, we ..

..Early failures are often associated with limb loss. Heavy tobacco use, younger age, early graft failures, repeat revascularization, and presentation with a thrombosed femoral-popliteal graft are associated with limb loss...

..This technique appears to offer reasonable patency and limb salvage rates in patients in whom autogenous bypass grafts are not feasible...

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..Infragenicular polytetrafluoroethylene (PTFE)-venous cuff bypass grafting provides acceptable graft patency and limb salvage rates for limb salvage...

..Objective criteria of the formation of AVF were worked out. The application of the criteria in operative treatment of 25 patients allowed the number of early thromboses to be reduced to 4%...

..Subintimal angioplasty has proved to be a useful and inexpensive way to treat intermittent claudication. For critical limb ischaemia, it has proved to be very effective...

..Kissing balloon technique with two low-profile catheters (KBT) could be the treatment of choice for diseased infrapopliteal artery bifurcation in critical limb ischemia (CLI)...

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..The precuffed ePTFE graft is an adequate alternative conduit for infragenicular arterial reconstruction in patients with critical limb ischemia and no available autologous veins...

..The pattern and distribution of arterial occlusions and stenoses in patients with critical limb ischemia presenting at two academic medical centers was described...

..The purpose of this study was to compare the clinical outcome of vein infrapopliteal bypass arising from the CFA and from the distal superficial femoral or popliteal and tibial arteries in patients with limb-threatening ischemia.

..005) and great saphenous vein versus PTFE graf (p < 0.05). These results show that popliteal-to-distal bypass is a safe and effective procedure with good long-term patency and limb salvage rates in selected cases...

..A precuffed graft is a reasonable alternative conduit for infragenicular reconstruction in the absence of saphenous vein and provides favorable limb salvage...

..PTA will become the initial treatment for most patients requiring lower-extremity revascularization...

..To evaluate the effectiveness of laser-assisted angioplasty for patients with critical limb ischemia (CLI) who were poor candidates for surgical revascularization...

..This study analyzed factors associated with percutaneous treatment failure, focusing specifically on lesion characteristics and treatment complexity...

..Thus, in a well defined subset of patients with recent onset CLI and SFA occlusion, antegrade popliteal DES supported angioplasty offers additional options for patients who might otherwise face amputation...

..It also can be used as an alternative to allow the long saphenous vein to be reserved for a bypass procedure in the future...

..Outflow angioplasty ameliorates the bypass flow and accelerates the healing of ischemic lesions. The restenosis rate of the inflow angioplasty at the femoral level remains low...

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..Further study of clinical outcome measures and comparison to other interventional techniques are warranted...

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..These findings support PE as a primary endovascular therapy for patients undergoing lower extremity arterial revascularization...

..This study reports the outcome of arterial revascularization procedures for chronic limb ischemia based on DUAM...

..Thus this simple and straightforward algorithm helped to secure the success of surgical therapy by shortening the time until wound-healing and reducing the psychosocial burden on the patient and financial costs to the health care system...

..The present study aimed to investigate the agreement between Duplex scanning and angiography in the diagnosis of stenosis in lower limb artery disease...

..To report the 12- and 24-month results after directional atherectomy (DA) of below-the-knee (BTK) arterial lesions with the SilverHawk device...

..A combination of the two in a modern operating room is a more logical approach...

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..In this article we report our recent experience in order to highlight this valuable and under-utilised technique, which was successful in a difficult case where a conventional approach failed...

..To report a safety and efficacy study of the first rotational aspiration atherectomy system (Pathway PV) for the treatment of arterial lesions below the femoral bifurcation...

..Sixteen-detector-row CT angiography using an adaptive acquisition improves the image quality and provides a reliable non-invasive technique to assess occlusive peripheral arterial disease, including distal foot arteries...

..This combined antegrade and retrograde subintimal approach is currently an excellent endovascular option in patients with long occlusions extending onto the leg vessels trifurcation and at risk of limb loss...

..To evaluate arterial patency and factors influencing outcomes after successful tibial artery angioplasty in patients with critical limb ischemia (CLI)...

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..Late failure of percutaneous therapies may often be treated successfully with reintervention, however. The continued accumulation of experience with PTA and stenting will ultimately define its role in the management of occlusive disease...

..However, bypass grafting should be mainly reserved to patients without severe cardiac disease and to those without extensive tissue loss...

..9% +/- 7% after 5 years. From these results we conclude that, with a limb salvage of 61.9%, PTFE is an acceptable alternative for a femorotibial bypass graft in patients with critical ischemia, if autologous vein is not available...

..2%. Most of the patients had occlusion of the femoral artery and lesions of the tibial arteries: one artery in 26 (70.2%), two arteries in 3 (8.1%) patients...

..To evaluate the feasibility, technical effectiveness and limb salvage potential of percutaneous transluminal angioplasty (PTA), particularly infrapopliteal, in diabetic subjects with ischaemic foot ulcer...

..Poor short-term results of thrombolysis of occluded prosthetic grafts support repeat operation with a completely new bypass graft as a more appropriate option...

..Runoff is known to negatively effect graft patency. The aim of this study is to examine the impact of distal runoff on long-term outcomes of SFA interventions for critical ischemia...

..To evaluate the effectiveness of complex endovascular treatment for limb salvage in patients with critical limb ischemia...

..The data evidence of LMWH benefits for the given interventions. Authors review the latest publications devoted to this problem and analyze the potential and special features of simultaneous anticoagulant therapy and regional anesthesia...

..The role and benefit of percutaneous transluminal angioplasty (PTA) for treatment of arteriosclerotic lesions in the crural arteries has been controversial. The purpose of this study was to review our experience...

..However, infrainguinal arterial reconstruction procedures performed in women have a worse outcome when compared with that in men...

..Limb salvage was achieved in this patient with a combination of endovascular and surgical techniques...

..CONCLUSIONS: Statin therapy is associated with improved graft patency after infrainguinal bypass grafting with saphenous vein...

..A novel alternative to standard angioplasty and stent is the excision of the obstructing arterial plaque using a minimally invasive technique, the Silverhawk Atherectomy device...

..These data suggest that IBA of the inflow SFA may be combined with popliteal to distal bypass graft and that this technique is a reasonable alternative to longer, femoral-origin bypass graft in selected diabetic patients with gangrene...

..Further experience should be acquired to assess its short- and long-term effects on this vascular territory...

..To compare a standard protocol for contrast-enhanced three-dimensional magnetic resonance angiography (3D CE-MRA) of the lower extremities to a high spatial resolution protocol with venous compression (VENCO) at the mid-femoral level...

..Therefore, this strategy can be considered an option for symptomatic relief and limb salvage in patients unsuitable for bypass surgery due to various reasons...

..To describe the extraosseous blood supply of the tibia and how the blood supply of the distal tibia is influenced by different plating techniques...

..Herein, we proposed a new alternative to avoid the harmful effects of radiation exposure and the risk of acute renal failure...

..This is an anatomical study to clarify the vascular anatomy of this region...

..To investigate the involvement of arteries other than the temporal arteries in active giant cell arteritis using color Doppler sonography...

..Six cases have been described previously. The purposes of this study were to report the prevalence of this injury and the variations in injury pattern and to characterize methods of treatment and patient outcomes...

..Ergotamine, an ergot alkaloid with partial agonist effects on alpha1 receptors and serotonin receptors, is widely used in the treatment of migraine. Ergotamine may cause severe vasospasm...

..Autologous vascularized epiphyseal transfer is the only possible procedure that can meet both requirements...

..Autologous vascularized epiphyseal transfer is the only possible procedure that can meet both requirements...

..This study evaluated the distribution and degree of symmetry of lower extremity artery stenoses in an unselected elderly population and its relation to a reduced ankle-brachial index (ABI) measurement...

..To report midterm results of infrainguinal bypasses performed with a heparin-bonded expanded polytetrafluoroethylene (ePTFE) graft in patients presenting with critical limb ischemia...

..Numerous cardiovascular mechanisms have been proposed to account for this problem, including vascular and cardiac dysfunction, which we studied during bed rest...

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..To compare multi-detector row spiral computed tomographic (CT) angiography with digital subtraction angiography (DSA) in evaluation of the infrarenal aorta and lower-extremity arterial system...

..We studied whether the diameter of the saphenous vein graft affects the result of femoro-popliteal bypass surgery...

..Special attention was paid to patients who suffered from Charcot-neuro-osteoarthropathy and the impact of Syme amputation if amputation of the foot was inevitable...

..A review of popliteal-crural bypasses via the posterior approach was done to evaluate the results of this technique...

..The purpose of this study was to evaluate the results of a vascularized bone graft transfer from the medial calcaneus to the large osteochondral lesion...

..To evaluate the efficacy and safety of a new atherectomy device for the treatment of infragenicular lesions in arteries with a reference diameter of at least 2.5 mm...

..We analyzed our experience of using the distal PA and inframalleolar or pedal branches arteries as outflow tracts in revascularizations for critical limb ischemia...

..To establish the experimental animal model of perforator sural neurocutaneous flap for laying a foundation of further study on its physiology and haemodynamics...

..The aim of this study was to evaluate the efficacy of a short course of exercise therapy in patients with moderate-to-severe intermittent claudication in terms of walking distance variations...

..Vessel diameter and flow were measured in the brachial and posterior tibial arteries using Doppler ultrasonography. Electrical tissue impedance was measured in the test limb...

..To more clearly define technical feasibility, patency, and clinical outcomes of SIA, we reviewed our cumulative experience...

..To evaluate the possibility of collateral outflow tract of arterial sclerosis obstruction (ASO) and the prospect of clinical application...

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..To investigate the characteristics of diabetic foot with neuropathy and its related factors...

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..These anomalies would determine secondary adaptations of muscles, tendons, vessels and nerves of the limb...

..Despite satisfactory tumor management, functional outcomes turned out to be variable, therefore precise ligament and muscle reconstruction is recommended...

..This study determined the reliable locations of the lower leg perforators...

..To investigate the anatomic structure of the compound flap of distally-based saphenous nerve-great saphenous vein nutritional vessels so as to provide anatomic basis for the clinical operation...

..end of fingers (or ankle and end of toes) and oscillometry over the radial and dorsalis pedis and posterior tibial arteries. Capillaroscopy of the conjunctival and nailfold vessels is useful in half the patients...

..The grafts combined a prosthetic femoropopliteal section with a popliteal to crural section with autologous vein, linked via a common intermediate anastomosis sited on the above-knee popliteal artery...

To evaluate the feasibility and efficacy of subintimal infrapopliteal angioplasty (SIA) as a method for recanalization of occluded tibial arteries in the treatment of critical limb ischaemia (CLI).

..Pedicled bone grafts using the main calcaneal branches were possible in 9 of 12 feet in which the superior calcaneal branches were not available. Finally, vascularized bone grafts were judged to be feasible in 27 feet (90%)...

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..We are unaware of any other population-based study that is as comprehensive as this to study the stated aims. ..

..Finally, the overrepresentation of ethnic minority groups in MESA will allow for testing of interactions with ethnicity. We are unaware of any other population-based study adequate to study the stated aims. ..

..This will have direct clinical relevance to the biology of vascular injury after percutaneous intervention in patients with metabolic syndrome and will help guide therapy. ..

..We are unaware of any other population-based study that is as comprehensive as this to study the stated aims. ..

..This will have direct clinical relevance to the biology of vascular injury after percutaneous intervention in patients with metabolic syndrome and will help guide therapy. ..

..Finally, the overrepresentation of ethnic minority groups in MESA will allow for testing of interactions with ethnicity. We are unaware of any other population-based study adequate to study the stated aims. ..

..These procedures will enable us to analyze the effects of the intervention on serious cardiovascular- related factors and complications, and cost-effectiveness of the intervention. ..

..By identifying the optimal exercise program for improving functioning in PAD patients with and without IC, our findings will have substantial clinical and public health implications for millions of patients with PAD. ..

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..In patients with vascular disease, arterial calcification is a strong predictor of restenosis. In this proposal, we will study why calcified arteries are prone to develop restenosis. ..

..We will test a novel clot-dissolving combination that may improve cellular function and outcomes after artery clotting. ..

..abstract_text> ..

..Results will be used to develop interventions to improve functioning and prevent functional decline in PAD. ..

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..The Specific Aim of this study will be to test the hypothesis that ROK and PKCzeta both mediate KCI- induced Ca sensitization of FA, and that iPLA2 and PI3K are required as upstream activators of ROK and PKCzeta. ..

..Findings may help clinicians identify patients who are at particularly high-risk for an impending heart attack. Results are also expected to elucidate specific triggers of acute coronary events. ..

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..These procedures will enable us to analyze the effects of the intervention on serious cardiovascular events, on CVD risk factors, diabetes related factors and complications, and cost-effectiveness of the intervention. ..

..Collectively, these studies will provide new insights into the cellular mechanisms regulating Ca2+ sensitivity and VSM reactivity to contractile stimuli. ..

..answer the following question: Is there a similar relationship between the amount of calcification found in tibial arteries and the severity of PVD in patients with type II diabetes? If this is the case, then tibial calcification ..

..Results will be used to develop interventions designed to improve lower extremity functioning and prevent functional decline in persons with PAD. ..

..Collectively, these studies will provide new insights into the cellular mechanisms regulating DSM contractions. ..

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..This knowledge, in subsequent studies, is expected to lead to new therapies for PAD-related functional impairment and functional decline. ..

..End of Abstract) ..

..This knowledge, in subsequent studies, is expected to lead to new therapies for PAD-related functional impairment and functional decline. ..

..Understanding the role of these calcium-controlling proteins in artery weakness and how drug therapy can interfere in these effects is an important step in the development of new treatment for aortic aneurysm. ..

..The proposed project will lay the foundation for the candidate's long-term career goal of designing system-based interventions aimed at eliminating disparities in cancer care and survival, a major objective of HealthyPeople 2010. ..

..The Specific Aim of this study will be to test the hypothesis that ROK and PKCzeta both mediate KCI- induced Ca sensitization of FA, and that iPLA2 and PI3K are required as upstream activators of ROK and PKCzeta. ..

..They further state that the results of this study will be used to develop subsequent intervention studies designed to improve quality of life and prevent functional decline among men and women with PAD. ..

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..This knowledge, in subsequent studies, is expected to lead to new therapies for PAD-related functional impairment and functional decline. ..

..It is expected that during this award period, Dr. Guzman will progress toward his goal of becoming an independent scientific investigator...

..Understanding the role of these calcium-controlling proteins in artery weakness and how drug therapy can interfere in these effects is an important step in the development of new treatment for aortic aneurysm. ..