common carotid artery

Summary

Summary: The two principal arteries supplying the structures of the head and neck. They ascend in the neck, one on each side, and at the level of the upper border of the thyroid cartilage, each divides into two branches, the external (CAROTID ARTERY, EXTERNAL) and internal (CAROTID ARTERY, INTERNAL) carotid arteries.

Top Publications

  1. ncbi Regression of the increased common carotid artery-intima media thickness in subclinical hypothyroidism after thyroid hormone replacement
    Soo Kyung Kim
    Department of Internal Medicine, CHA University School of Medicine, Sungnam, Korea
    Endocr J 56:753-8. 2009
  2. ncbi Arterial wave reflections and survival in end-stage renal failure
    G M London
    Service d Hemodialyse, Hôpital F H Manhès, Fleury Merogis, Ste Genevieve des Bois, France
    Hypertension 38:434-8. 2001
  3. ncbi Arterial wall thickening and stiffening in children and adolescents with type 1 diabetes
    Mehmet Emre Atabek
    Department of Pediatric Endocrinology and Diabetes, School of Medicine, Selcuk University, Konya, Turkey
    Diabetes Res Clin Pract 74:33-40. 2006
  4. ncbi Anatomic relationship of the internal jugular vein and the common carotid artery applied to percutaneous transjugular procedures
    Ulku C Turba
    Interventional Radiology, Medical University of South Carolina, 169 Ashley Avenue, Charleston, SC 29425, USA
    Cardiovasc Intervent Radiol 28:303-6. 2005
  5. ncbi Pial microvascular responses to transient bilateral common carotid artery occlusion: effects of hypertonic glycerol
    D Lapi
    Department of Physiology and Biochemistry, University of Pisa, Pisa, Italy
    J Vasc Res 45:89-102. 2008
  6. ncbi Effects of PCSK9 variants on common carotid artery intima media thickness and relation to ApoE alleles
    Giuseppe Danilo Norata
    Department of Pharmacological Sciences, Universita degli Studi di Milano, Via Balzaretti 9, Milan, Italy
    Atherosclerosis 208:177-82. 2010
  7. ncbi Ultrasonic evaluation of early atherosclerosis in children and adolescents with type 1 diabetes mellitus
    Taner Yavuz
    J Pediatr Endocrinol Metab 15:1131-6. 2002
  8. ncbi Circumferential strain in the wall of the common carotid artery: comparing displacement-encoded and cine MRI in volunteers
    Alexander P Lin
    Bioengineering, California Institute of Technology, Pasadena, CA 91125, USA
    Magn Reson Med 60:8-13. 2008
  9. ncbi Magnitude of alimentary lipemia is related to intima-media thickness of the common carotid artery in middle-aged men
    F Karpe
    King Gustaf V Research Institute, Department of Emergency and Cardiovascular Medicine, Karolinska Hospital, Stockholm, Sweden
    Atherosclerosis 141:307-14. 1998
  10. ncbi VEGF overexpression improves mice cognitive abilities after unilateral common carotid artery occlusion
    Konstanze Plaschke
    Department of Anesthesiology, Medical Faculty, University of Heidelberg, Germany
    Exp Neurol 214:285-92. 2008

Research Grants

  1. Middle Cerebral and Common Artery Occlusion and Poststroke Epilepsy
    Kevin Kelly; Fiscal Year: 2007
  2. Circuit Weight Training and Blood Pressure Regulation in Prehypertension
    William Cooke; Fiscal Year: 2007
  3. Jun Kinase Signaling and Apoptosis in Ischemia Stroke
    Chia Yi Kuan; Fiscal Year: 2006
  4. NITRIC OXIDE IN ATHEROGENESIS AND ARTERIAL RELAXATION
    Richard Cohen; Fiscal Year: 1999
  5. Laser Catheter for Dethrombosis of Arterial Occlusion
    Brant Watson; Fiscal Year: 2005
  6. Phytoestrogens and Progression of Atherosclerosis
    HOWARD HODIS; Fiscal Year: 2007
  7. Intracranial Aneurysm Pathogenesis-Roles of Vascular Remodeling and Inflammation
    Tomoki Hashimoto; Fiscal Year: 2010
  8. Intracranial Aneurysm Pathogenesis-Roles of Vascular Remodeling and Inflammation
    Tomoki Hashimoto; Fiscal Year: 2007
  9. IMPORTANCE OF THE BLOOD-BRAIN BARRIER IN STROKE
    W Dietrich; Fiscal Year: 1993
  10. Prevention of Diabetes in Obese Hispanic Adolescents
    Martha Cruz; Fiscal Year: 2005

Detail Information

Publications193 found, 100 shown here

  1. ncbi Regression of the increased common carotid artery-intima media thickness in subclinical hypothyroidism after thyroid hormone replacement
    Soo Kyung Kim
    Department of Internal Medicine, CHA University School of Medicine, Sungnam, Korea
    Endocr J 56:753-8. 2009
    ..whether subclinical hypothyroidism is associated with an increase in the intima-media thickness of the common carotid artery (C-IMT) and whether thyroid hormone replacement can reverse this change in the C-IMT...
  2. ncbi Arterial wave reflections and survival in end-stage renal failure
    G M London
    Service d Hemodialyse, Hôpital F H Manhès, Fleury Merogis, Ste Genevieve des Bois, France
    Hypertension 38:434-8. 2001
    The increased effect of arterial wave reflections on central arteries like the common carotid artery seen in end-stage renal failure (ESRF) patients favors myocardial hypertrophy and oxygen consumption and alters coronary blood flow ..
  3. ncbi Arterial wall thickening and stiffening in children and adolescents with type 1 diabetes
    Mehmet Emre Atabek
    Department of Pediatric Endocrinology and Diabetes, School of Medicine, Selcuk University, Konya, Turkey
    Diabetes Res Clin Pract 74:33-40. 2006
    We evaluated structural and functional characteristics of the common carotid artery (CCA), a marker of early carotid atherosclerosis, and investigated their relation to metabolic and anthropometric parameters in children and adolescents ..
  4. ncbi Anatomic relationship of the internal jugular vein and the common carotid artery applied to percutaneous transjugular procedures
    Ulku C Turba
    Interventional Radiology, Medical University of South Carolina, 169 Ashley Avenue, Charleston, SC 29425, USA
    Cardiovasc Intervent Radiol 28:303-6. 2005
    PURPOSE: To demonstrate the anatomic relationship of the internal jugular vein (IJV) with the common carotid artery (CCA) in order to avoid inadvertent puncture of the CCA during percutaneous central venous access or transjugular ..
  5. ncbi Pial microvascular responses to transient bilateral common carotid artery occlusion: effects of hypertonic glycerol
    D Lapi
    Department of Physiology and Biochemistry, University of Pisa, Pisa, Italy
    J Vasc Res 45:89-102. 2008
    The aim of the study was to assess the rat pial microvessel alterations due to transient bilateral common carotid artery occlusion (BCCAO) and to investigate the mechanism of 10% hypertonic glycerol neuroprotection...
  6. ncbi Effects of PCSK9 variants on common carotid artery intima media thickness and relation to ApoE alleles
    Giuseppe Danilo Norata
    Department of Pharmacological Sciences, Universita degli Studi di Milano, Via Balzaretti 9, Milan, Italy
    Atherosclerosis 208:177-82. 2010
    ..PCSK9 plays a key role in plasma cholesterol metabolism by modulating the expression of LDL receptors...
  7. ncbi Ultrasonic evaluation of early atherosclerosis in children and adolescents with type 1 diabetes mellitus
    Taner Yavuz
    J Pediatr Endocrinol Metab 15:1131-6. 2002
    ....
  8. ncbi Circumferential strain in the wall of the common carotid artery: comparing displacement-encoded and cine MRI in volunteers
    Alexander P Lin
    Bioengineering, California Institute of Technology, Pasadena, CA 91125, USA
    Magn Reson Med 60:8-13. 2008
    ..We employed a displacement encoding with stimulated echoes (DENSE) sequence to image the motion of the common carotid artery wall and map the two-dimensional (2D) circumferential strain...
  9. ncbi Magnitude of alimentary lipemia is related to intima-media thickness of the common carotid artery in middle-aged men
    F Karpe
    King Gustaf V Research Institute, Department of Emergency and Cardiovascular Medicine, Karolinska Hospital, Stockholm, Sweden
    Atherosclerosis 141:307-14. 1998
    ..after oral fat intake, an estimate of the intima-media thickness (IMT) was made using ultrasound of the common carotid artery, and postprandial TRL was quantified during a standardized oral fat tolerance test in 30 healthy normo- ..
  10. ncbi VEGF overexpression improves mice cognitive abilities after unilateral common carotid artery occlusion
    Konstanze Plaschke
    Department of Anesthesiology, Medical Faculty, University of Heidelberg, Germany
    Exp Neurol 214:285-92. 2008
    ..In 33 V1 and wild-type (wt) mice, the left common carotid artery was permanently occluded (CCAO) under acute (48 h) and subchronic (12 days) conditions...
  11. ncbi Intensive diabetes therapy and carotid intima-media thickness in type 1 diabetes mellitus
    David M Nathan
    DCCT EDIC Research Group at Box NDIC DCCT, Bethesda, MD 20892, USA
    N Engl J Med 348:2294-303. 2003
    ..We examined the progression of carotid intima-media thickness, a measure of atherosclerosis, in a population with type 1 diabetes...
  12. ncbi Leptin:adiponectin ratio is an independent predictor of intima media thickness of the common carotid artery
    Giuseppe Danilo Norata
    Stroke 38:2844-6. 2007
    ..52) (P<0.01). CONCLUSIONS: We show here that the L:A ratio is a powerful independent predictor of IMT in healthy subjects and correlates with several anthropometric, metabolic, and clinical parameters better than each single adipokine...
  13. ncbi Cardiovascular risk factors and common carotid artery caliber and stiffness in patients with Cushing's disease during active disease and 1 year after disease remission
    Antongiulio Faggiano
    Department of Molecular and Clinical Endocrinology and Oncology, Federico II University, Naples, Italy
    J Clin Endocrinol Metab 88:2527-33. 2003
    ..The persistence of a metabolic syndrome, vascular damage, and atherosclerotic plaques after cortisol level normalization makes these subjects still at high cardiovascular risk despite disease remission...
  14. ncbi Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2: a double-blind, placebo-controlled study of extended-release niacin on atherosclerosis progression in secondary prevention patients treated with statins
    Allen J Taylor
    Cardiovascular Research, Cardiology Service, Walter Reed Army Medical Center, 6900 Georgia Ave, NW, Bldg 2, Room 3L28, Washington, DC 20307 5001, USA
    Circulation 110:3512-7. 2004
    ..Niacin reduces coronary heart disease morbidity and mortality when taken either alone or in combination with statins; however, the incremental impact of adding niacin to background statin therapy is unknown...
  15. ncbi In vivo quantification of carotid artery wall dimensions: 3.0-Tesla MRI versus B-mode ultrasound imaging
    R Duivenvoorden
    Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Circ Cardiovasc Imaging 2:235-42. 2009
    ..Our aim was to compare common carotid mean wall thickness (MWT) measurements by 3.0-T MRI with B-mode ultrasound common carotid intima-media thickness (CCIMT) measurements, a validated surrogate marker for cardiovascular disease...
  16. ncbi Idiopathic free-floating thrombus of the common carotid artery
    Brian Silver
    Department of Neurology, Henry Ford Hospital, Detroit, MI 48202, USA
    Can J Neurol Sci 29:97-9. 2002
    BACKGROUND: The observation of an intraluminal common carotid artery thrombus overlying a wall defect at ultrasonography or angiography is unusual...
  17. ncbi Interrelations between brachial endothelial function and carotid intima-media thickness in young adults: the cardiovascular risk in young Finns study
    Markus Juonala
    Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland
    Circulation 110:2918-23. 2004
    ..These observations suggest that endothelial dysfunction is an early event in atherosclerosis and that the status of systemic endothelial function may modify the association between risk factors and atherosclerosis...
  18. ncbi Duplex ultrasonography of the common carotid artery and external jugular vein of cows
    Ueli Braun
    Department of Farm Animals, Veterinary Faculty, University of Zurich, Winterthurerstrasse 260, CH-8057 Zurich, Switzerland
    Am J Vet Res 66:962-5. 2005
    OBJECTIVE: To determine blood flow patterns in the common carotid artery and external jugular vein in cows before and after sedation achieved by administration of xylazine hydrochloride. ANIMALS: 30 clinically normal Swiss Braunvieh cows...
  19. ncbi Effects of fractalkine receptor variants on common carotid artery intima-media thickness
    Giuseppe D Norata
    Department of Pharmacological Sciences, University of Milan, Italy
    Stroke 37:1558-61. 2006
    ..In the present study, we investigated the possible association between CX3CR1variants and intima-media thickness (IMT)...
  20. ncbi Enhanced atherothrombotic formation after oxidative injury by FeCl3 to the common carotid artery in severe combined hyperlipidemic mice
    Xunde Xian
    Institute of Cardiovascular Sciences and Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Peking University Health Science Center, 38 Xueyuan Road, Haidian District, Beijing 100191, China
    Biochem Biophys Res Commun 385:563-9. 2009
    ..Conclusions: Severe combined hyperlipidemia promotes thrombosis after ferric chloride injury to atherosclerotic vessels and HTG plays a major role in the process...
  21. ncbi [A case of aneurysmal subarachnoid hemorrhage associated with bilateral common carotid artery occlusion]
    Tomohiro Araki
    Department of Neurosurgery, Mie University School of Medicine, 2-174 Edobashi, Tsu-city, Mie 514-8507, Japan
    No Shinkei Geka 30:853-8. 2002
    ..of the literature, only four cases of aneurysmal subarchnoid hemorrhage (SAH) associated with bilateral common carotid artery occlusion (CCAO) have been reported in addition to the case we report here with a summary of the ..
  22. ncbi Endovascular repair of ascending aortic pseudoaneurysm: technical considerations of a common carotid artery approach using the Zenith aortic cuff endograft
    Peter H Lin
    Division of Vascular Surgery and Endovascular Therapy, Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas 77030, USA
    J Endovasc Ther 14:794-8. 2007
    To present a technique for endovascular treatment using Zenith aortic cuff extenders delivered via a left common carotid artery (CCA) approach in a patient with a large symptomatic ascending aortic pseudoaneurysm.
  23. ncbi Measurement of common carotid artery lumen dynamics during the cardiac cycle using magnetic resonance TrueFISP cine imaging
    Tracy Y Chow
    Laboratory of Biomedical Imaging and Signal Processing, University of Hong Kong, Pokfulam, Hong Kong
    J Magn Reson Imaging 28:1527-32. 2008
    ....
  24. ncbi [Influence of moxibustion of baihui (GV 20) on hemodynamics of common carotid artery in healthy subjects]
    Ning xia Zhao
    Tangdu Hospital of the Fourth Military Medical University, Xi an, China
    Zhen Ci Yan Jiu 32:252-4. 2007
    ..To observe the effect of moxibustion of Baihui (GV 20) on the hemodynamics of internal carotid artery in health subjects so as to study its underlying mechanism of moxibustion in the treatment cerebrovascular disorders...
  25. ncbi The effect of temporary aneurysm clip on the common carotid artery of atherosclerotic rabbits
    Murat Cosar
    Neurosurgery, Faculty of Medicine, Kocatepe University, Afyon 03200, Turkey
    Surg Neurol 69:483-8; discussion 489. 2008
    ..We compared the effect of temporary aneurysm clips on atherosclerotic and nonatherosclerotic CCA of rabbits by morphometric and ultrastructural methods...
  26. ncbi Carotid intima-media thickness in children and young adults with renal transplant: Internal carotid artery vs. common carotid artery
    Yelda Bilginer
    Department of Pediatric Nephrology, Hacettepe University Faculty of Medicine, Ankara, Turkey
    Pediatr Transplant 11:888-94. 2007
    ..These changes can be detected by measuring CCA/ICA-IMT ultrasonographically. We suggest that early renal transplantation can potentially avoid long-term cardiovascular events in children with end stage kidney disease...
  27. ncbi WISE-2005: reduced cerebral blood flow velocity with nitroglycerin--comparison with common carotid artery blood flow
    K A Zuj
    Cardiorespiratory and Vascular Dynamics Lab, Univ Waterloo, Waterloo, Ontario, Canada
    J Gravit Physiol 14:P65-6. 2007
    ..artery (MCA), the change in CBV in the MCA was compared with changes in quantitative flow measured in the common carotid artery (CCA)...
  28. ncbi Intima-media complex of both the brachial artery and the common carotid artery are associated with left ventricular hypertrophy in patients with previous myocardial infarction
    Stefan Agewall
    Department of Cardiology, Huddinge University Hospital, Karolinska Institute, Stockholm, Sweden
    J Hypertens 23:119-25. 2005
    ..The aim of this study was to examine the relationship between intima-media complex of the brachial artery to FMD, intima-media complex of the common carotid artery and cardiac hypertrophy in patients with coronary heart disease.
  29. ncbi Fully automated common carotid artery and internal jugular vein identification and tracking using B-mode ultrasound
    David C Wang
    University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    IEEE Trans Biomed Eng 56:1691-9. 2009
    We describe a fully automated ultrasound analysis system that tracks and identifies the common carotid artery (CCA) and the internal jugular vein (IJV)...
  30. ncbi In vivo tracking of dual-labeled mesenchymal stem cells homing into the injured common carotid artery
    Ai hong Cao
    Jiangsu Key Laboratory of Molecular and Functional Imaging, Department of Radiology, Zhongda Hospital, Southeast University, Nanjing 210009, China
    Anat Rec (Hoboken) 292:1677-83. 2009
    ..resonance imaging of labeled rat bone mesenchymal stem cells (BMSCs) as they home into the site of injured common carotid artery following allograft transplantation...
  31. ncbi Impact of prehypertension on common carotid artery intima-media thickness and left ventricular mass
    Efstathios Manios
    Department of Clinical Therapeutics, University of Athens School of Medicine, Alexandra Hospital, Athens, Greece
    Stroke 40:1515-8. 2009
    ..The aim of our study was to assess the extent of CCA-IMT and left ventricular mass (LVM) in prehypertensive adults in comparison to normotensive and untreated hypertensive subjects...
  32. ncbi Does B-mode common carotid artery intima-media thickness differ from M-model?
    L M van Bortel
    Department of Pharmacology, Maastricht University, Cardiovascular Research Institute Maastricht CARIM, Maastricht, The Netherlands
    Ultrasound Med Biol 27:1333-6. 2001
    An increased intima-media thickness of the common carotid artery is thought to be an early sign of atherosclerosis...
  33. ncbi Measurement of common carotid artery intima-media thickness in clinical practice: comparison of B-mode and RF-based technique
    F H Schreuder
    Department of Clinical Neurophysiology, Maastricht University Medical Centre, 6202 AZ Maastricht, Netherlands
    Ultraschall Med 30:459-65. 2009
    The common carotid artery intima-media thickness (CCA-IMT) is usually measured using B-mode ultrasound images. A different approach for CCA-IMT detection is based on radio frequency (RF) multiple M-line analysis.
  34. ncbi Intima-media thickness: a new tool for diagnosis and treatment of cardiovascular risk
    Alain Simon
    Centre de Medecine Preventive Cardiovasculaire, Hopital Broussais, Paris, France
    J Hypertens 20:159-69. 2002
    ..sites in near and far walls and (ii) computerized measurement restricted to the far wall of the distal common carotid artery. Because IMT reflects global cardiovascular risk, its normal value might be better defined in terms of ..
  35. ncbi Accelerated atherosclerosis in patients with Wegener's granulomatosis
    K de Leeuw
    Department of Clinical Immunology, University Hospital, PO Box 30 001, 9700 RB Groningen, Netherlands
    Ann Rheum Dis 64:753-9. 2005
    ..In addition to traditional risk factors, non-traditional risk factors such as endothelial activation and excessive vascular remodelling might be determinants of the progression of atherosclerosis in patients with an autoimmune disease...
  36. ncbi Angiotensin-converting enzyme inhibition with enalapril slows progressive intima-media thickening of the common carotid artery in patients with non-insulin-dependent diabetes mellitus
    N Hosomi
    Second Department of Internal Medicine, Kagawa Medical University School of Medicine, Kagawa, Japan
    Stroke 32:1539-45. 2001
    ..01+/-0.004 mm/y relative to the control group over the course of this study. CONCLUSIONS: Long-term treatment with an ACE inhibitor (enalapril) slows progressive IM thickening of the common carotid artery in NIDDM patients.
  37. ncbi Angiotensin-converting enzyme I/D polymorphism and macrovascular disease in systemic sclerosis
    F Bartoli
    Department of Medicine Section of Rheumatology, Villa Monna Tessa, Viale Pieraccini 18, 50122 Firenze, Italy
    Rheumatology (Oxford) 46:772-5. 2007
    ..This study evaluates the relationship between intima-media thickness (IMT), ankle-brachial pressure measurements (ABPI) and ACE I/D polymorphism in SSc patients...
  38. ncbi Relationship of lumen diameter to type and degree of arterial remodeling at sites of expanding wall or plaque thickness in human carotid artery
    Robert A Boyajian
    Department of Medicine, Division of Neurology, Center for Brain Research and Treatment, Scripps Clinic, La Jolla, Calif, USA
    Cerebrovasc Dis 17:228-37. 2004
    ..Direction and magnitude of vessel remodeling are calculated for internal carotid, bifurcation, and common carotid artery segments...
  39. ncbi Snakes based segmentation of the common carotid artery intima media
    C P Loizou
    Intercollege, Department of Computer Science, School of Sciences and Engineering, 92 Ayias Phylaxeos Str, P O Box 51604, CY 3507, Limassol, Cyprus
    Med Biol Eng Comput 45:35-49. 2007
    ..we present a snakes segmentation technique for detecting the intima-media layer of the far wall of the common carotid artery (CCA) in longitudinal ultrasound images, by applying snakes, after normalization, speckle reduction, and ..
  40. ncbi Endothelial dysfunction precedes atherosclerosis in systemic sclerosis--relevance for prevention of vascular complications
    G Szucs
    3rd Department of Internal Medicine, Rheumatology Division, University of Debrecen, Medical and Health Science Center, Hungary, Moricz Zs Krt 22, H 4004 Debrecen, Hungary E mail
    Rheumatology (Oxford) 46:759-62. 2007
    ....
  41. ncbi Common carotid artery intima-media thickness in patients with brain infarction and intracerebral haemorrhage
    Konstantinos N Vemmos
    Department of Clinical Therapeutics, University of Athens, Alexandra Hospital, Athens, Greece
    Cerebrovasc Dis 17:280-6. 2004
    An increase in the intima-media thickness of the common carotid artery (CCA-IMT) is generally considered as an early marker of atherosclerosis and has been associated with a higher risk of stroke and myocardial infarction...
  42. ncbi Which factors are related to the presence of atherosclerosis in rheumatoid arthritis?
    S Wallberg-Jonsson
    Department of Rheumatology, University Hospital of Umea, Sweden
    Scand J Rheumatol 33:373-9. 2004
    ..The results are based on the co-analysis of retrospective data as well as cross-sectional data. The impact of RA per se on atherosclerosis was evaluated relative to age- and sex-matched controls...
  43. ncbi Migrating foreign body into the common carotid artery
    Kenny Peter Pang
    Department of Otolaryngology, Singapore General Hospital, Singapore
    Otolaryngol Head Neck Surg 132:667-8. 2005
  44. ncbi Assessment by cardiovascular magnetic resonance, electron beam computed tomography, and carotid ultrasonography of the distribution of subclinical atherosclerosis across Framingham risk strata
    Sekar Kathiresan
    Framingham Heart Study, Framingham, Massachusetts, USA
    Am J Cardiol 99:310-4. 2007
    ..In conclusion, in a community-based sample, correlations among subclinical atherosclerosis test results are low, and a substantial proportion has high levels of subclinical atherosclerosis detected on >or=2 imaging tests...
  45. ncbi Carotid-compression technique for the insertion of guiding catheters
    S Yoshimura
    Department of Neurosurgery, Graduate School of Medicine, Division of Neuroscience, Gifu University Asahi, Japan
    AJNR Am J Neuroradiol 27:1710-1. 2006
    ..Although this technique is not risk-free and care must be taken to avoid vascular injury by excessive compression, it is useful for the insertion of a guiding catheter into the carotid artery...
  46. ncbi Common carotid arterial interadventitial distance (diameter) as an indicator of the damaging effects of age and atherosclerosis, a cross-sectional study of the Atherosclerosis Risk in Community Cohort Limited Access Data (ARICLAD), 1987-89
    Marsha L Eigenbrodt
    Department of Epidemiology, Fay W Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, USA
    Cardiovasc Ultrasound 4:1. 2006
    The effect of age on common carotid artery diameter is unclear for varying atherosclerosis risk levels.
  47. ncbi Common carotid intima-media thickness is predictive of all-cause and cardiovascular mortality in elderly community-dwelling people: Longitudinal Investigation for the Longevity and Aging in Hokkaido County (LILAC) study
    S Murakami
    Department of Medicine, Medical Center East, Tokyo Women's Medical University, Nishiogu 2-1-10, Arakawa, Tokyo 116-8567, Japan
    Biomed Pharmacother 59:S49-53. 2005
    ..351 (1.029-5.372) and 2.890 (1.059-7.891), respectively. Carotid IMT assessed by ultrasonography is positively associated with an increased risk of all-cause and cardiovascular death in elderly community-dwelling people...
  48. ncbi Time rate of blood pressure variation is associated with increased common carotid artery intima-media thickness
    Nikos A Zakopoulos
    Department of Clinical Therapeutics Alexandra Hospital, University of Athens, Greece
    Hypertension 45:505-12. 2005
    ..systolic BP (SBP) variation derived from ambulatory BP monitoring (ABPM) data analysis and the extent of common carotid artery (CCA) intima-media thickness (IMT) in normotensive (n=280) and in uncomplicated hypertensive subjects (n=..
  49. ncbi Sample size calculation for clinical trials using magnetic resonance imaging for the quantitative assessment of carotid atherosclerosis
    Tobias Saam
    Department of Radiology, University of Washington, Seattle, Washington 98195, USA
    J Cardiovasc Magn Reson 7:799-808. 2005
    ..This study provides the basis for sample size calculation of future MRI trials...
  50. ncbi p47phox-dependent NADPH oxidase regulates flow-induced vascular remodeling
    Yves Castier
    INSERM Centre de Recherche Cardiovasculaire Lariboisiere, Paris, France
    Circ Res 97:533-40. 2005
    ..in this process, we developed a new model of mouse arteriovenous fistula (AVF) connecting the right common carotid artery (RCCA) with the jugular vein, which does not affect blood pressure...
  51. ncbi Are your arteries older than your age?
    N Labropoulos
    Department of Surgery, Loyola University Medical Center, Maywood, IL 60153 3304, USA
    Eur J Vasc Endovasc Surg 30:588-96. 2005
    ..To determine the effect of age and atherosclerotic risk factors on the carotid intima-media layer thickness and morphology characteristics...
  52. ncbi Catheterization of the hepatic artery via the left common carotid artery in rats
    Xiao Li
    Department of Radiology, West China Hospital, Sichuan University, Chengdu, People's Republic of China
    Cardiovasc Intervent Radiol 29:1073-6. 2006
    ..A new method of rat hepatic artery catheterization via the left common carotid artery (LCCA) is described. The LCCA is repaired after catheterization...
  53. ncbi Chronic bilateral common carotid artery occlusion: a model for ocular ischemic syndrome in the rat
    Daniel Lavinsky
    Biochemistry Department, ICBS, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil
    Graefes Arch Clin Exp Ophthalmol 244:199-204. 2006
    ..The reduction of blood flow produced by bilateral common carotid artery occlusion (BCCAO) of rats for 7 days induces events related to gliosis with no evident histological damage...
  54. ncbi Incident coronary events and case fatality in relation to common carotid intima-media thickness
    M Rosvall
    Department of Community Medicine, Lund University, Malmo University Hospital, Malmo, Sweden
    J Intern Med 257:430-7. 2005
    ..To evaluate the incidence of coronary events (CE) and case fatality in relation to common carotid intima-media thickness (IMT) and carotid plaque over a median follow up of 7 years...
  55. ncbi A rare anomalous origin of right vertebral artery: findings on Doppler sonography
    Bahar Yanik
    Department of Radiology, Social Security Ankara Hospital, , Ankara, Turkey
    J Clin Ultrasound 32:211-4. 2004
    Anomalous origin of the right vertebral artery from the right common carotid artery occurs rarely...
  56. ncbi Permanent, bilateral common carotid artery occlusion in the rat: a model for chronic cerebral hypoperfusion-related neurodegenerative diseases
    Eszter Farkas
    Department of Anatomy, School of Medicine, University of Szeged, H 6701 Szeged, P O Box 427, Hungary
    Brain Res Rev 54:162-80. 2007
    ..Thorough characterization of the model suggests that 2VO in the rat is suitable for the development of potentially neuroprotective strategies in neurodegenerative diseases...
  57. ncbi Shear stress in the common carotid artery is related to both intima-media thickness and echogenecity. The Prospective Investigation of the Vasculature in Uppsala Seniors study
    Lars Lind
    Department of Medicine, Uppsala University Hospital, Uppsala, Sweden
    Clin Hemorheol Microcirc 43:299-308. 2009
    ..the Vasculature in Uppsala Seniors (PIVUS) study, a population-based study of 1016 subjects aged 70, left common carotid artery diameter, IMT, the grey scale median (GSM) of the intima-media complex (IM-GSM) and the blood flow ..
  58. ncbi Increased thickness of the arterial intima-media detected by ultrasonography in patients with rheumatoid arthritis
    Yasuro Kumeda
    Division of Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan
    Arthritis Rheum 46:1489-97. 2002
    ..141 mm, respectively). Multiple regression analysis revealed a significant association between RA and the common carotid artery IMT...
  59. ncbi Comparison of the effects of losartan and atenolol on common carotid artery intima-media thickness in patients with hypertension: results of a 2-year, double-blind, randomized, controlled study
    Malte Ludwig
    University Clinic Bonn, Department of Medicine, Germany
    Clin Ther 24:1175-93. 2002
    ..and the beta-blocker atenolol on ultrasonographically determined intimamedia thickness (IMT) of the common carotid artery (CCA) in patients with mild to moderate essential hypertension...
  60. ncbi Body composition and common carotid artery remodeling in a healthy population
    Michaela Kozakova
    Department of Internal Medicine, University of Pisa, Via Roma 67, 56126 Pisa, Italy
    J Clin Endocrinol Metab 93:3325-32. 2008
    ..Body composition (BC) influences systemic hemodynamics and may participate in the remodeling of common carotid artery (CCA), independently of risk factors.
  61. ncbi Persistent impairment of gait performances and working memory after bilateral common carotid artery occlusion in the adult Wistar rat
    Cristina Sarti
    Department of Neurological and Psychiatric Sciences, University of Florence, Viale Morgagni 85, 50134 Firenze, Italy
    Behav Brain Res 136:13-20. 2002
    ..We investigated whether rats subjected to bilateral common carotid artery occlusion (bCCA-o) developed focal neurological deficits, gait dysfunction, and working memory alterations...
  62. ncbi Mucormycotic pseudoaneurysm of the common carotid artery with tracheal involvement
    S Hashemzadeh
    Mycoses 51:347-51. 2008
    ..Doppler ultrasonography and angiography of the neck revealed a pseudoaneurysm of the right common carotid artery. The patient then developed haemoptysis...
  63. ncbi Risk factors for progression of common carotid atherosclerosis: the Atherosclerosis Risk in Communities Study, 1987-1998
    Lloyd E Chambless
    Department of Biostatistics, School of Public Health, University of North Carolina, Chapel Hill, NC 27514 4145, USA
    Am J Epidemiol 155:38-47. 2002
    ..In summary, established risk factors for coronary heart disease are associated with the rate of change of subclinical atherosclerosis...
  64. ncbi Radiation effects on the intima-media thickness of the common carotid artery in post-radiotherapy patients with head and neck malignancy
    M Shariat
    Radiology Department, Hospital Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia
    Postgrad Med J 84:609-12. 2008
    ..In this study, irradiated subjects with major risk factors such as hypertension, diabetes, history of previous cerebrovascular accident and connective tissue disorder were excluded...
  65. ncbi Increased stiffness in common carotid artery in hyperthyroid Graves' disease patients
    M Inaba
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Biomed Pharmacother 56:241-6. 2002
    The present study was undertaken to assess the effect of hyperthyroidism on stiffness in the common carotid artery (CCA) in patients with Graves' disease (GD) and elucidate the mechanism by which arterial stiffness is increased in ..
  66. ncbi Relation between depressive symptoms and common carotid artery atherosclerosis in American persons > or =65 years of age
    Mohammed F Faramawi
    Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA
    Am J Cardiol 99:1610-3. 2007
    ..and could not determine the temporality between depressive symptoms and the development of abnormal common carotid artery (CCA) intima-media thickness (CCA-IMT)...
  67. ncbi Quantitative measurement of carotid intima-media roughness--effect of age and manifest coronary artery disease
    Arno Schmidt-Trucksäss
    Department of Rehabilitative and Preventative Sports Medicine, Center for Internal Medicine, Freiburg University Hospital, Hugstetter Street 55, D 79106 Freiburg, Germany
    Atherosclerosis 166:57-65. 2003
    Atherosclerotic changes of the common carotid artery (CCA) may appear like irregularities of the intima-media thickness (abbreviated as IM roughness) in B-mode ultrasound...
  68. ncbi Effects of blood pressure lowering with amlodipine or lisinopril on vascular structure of the common carotid artery
    A V Stanton
    Peart Rose Clinic, Department of Clinical Pharmacology, National Heart and Lung Institute, Imperial College School of Medicine, St Mary s Hospital, London W2 1PG, UK
    Clin Sci (Lond) 101:455-64. 2001
    Increased intima-media thickness of the common carotid artery predicts increased risk of myocardial infarction and stroke. Preliminary evidence suggests that a decrease in blood pressure (BP) is associated with diminished wall thickness...
  69. ncbi Mycotic aneurysm of common carotid artery induced by Staphylococcus aureus infection after cervical reoperation
    A Machens
    Department of General Surgery, Martin Luther University, Halle Wittenberg, Ernst Grube Strasse 40, D 06097 Halle Saale, Germany
    World J Surg 25:1113-6. 2001
    ..We retrospectively analyzed all staphylococcal mycotic aneurysms of the common carotid artery. These aneurysms had developed after reoperative thyroid or parathyroid surgery, including resection of ..
  70. ncbi High bifurcation of common carotid artery, anomalous origin of ascending pharyngeal artery and anomalous branching pattern of external carotid artery
    V Gluncic
    Drago Perovic Department of Anatomy, Zagreb University School of Medicine, alata 11, HR 10000 Zagreb, Croatia
    Surg Radiol Anat 23:123-5. 2001
    We present a rare case of combined high bifurcation of the common carotid artery, anomalous origin of the ascending pharyngeal artery and unusual branching pattern of the external carotid artery...
  71. ncbi Correlations between measures of atherosclerosis change using carotid ultrasonography and coronary angiography
    W J Mack
    Atherosclerosis Research Unit, University of Southern California, Los Angeles, CA, USA
    Atherosclerosis 150:371-9. 2000
    ..Significant correlations between change in common carotid artery IMT and quantitative coronary angiographic measures of change were evident over all coronary artery ..
  72. ncbi Reproducibility of ultrasonographically determined intima-media thickness is dependent on arterial wall thickness. The Tromsø Study
    E Stensland-Bugge
    Institute of Community Medicine, University of Tromsø, Norway
    Stroke 28:1972-80. 1997
    ....
  73. ncbi The stiffness of the common carotid artery in patients with Graves' disease
    M Czarkowski
    Department of Internal Medicine and Endocrinology, University Medical School of Warsaw, Warsaw, Poland
    Int Angiol 21:152-7. 2002
    ..We hypothesised that mechanical properties of the large arteries are also involved in hyperthyroidism-induced cardiovascular changes and set out to investigate this further...
  74. ncbi High-sensitivity C-reactive protein is independently associated with early carotid artery progression in women but not in men: the INVADE Study
    Kerstin Sander
    Department of Neurology, Technical University of Munich, Mohlstrasse 28, 81675 Munchen, Germany
    Stroke 38:2881-6. 2007
    ..Therefore, we investigated the effect of hsCRP on early carotid atherosclerosis progression and major vascular risk factors in men and women...
  75. ncbi Arterial structure and function in young adults with the metabolic syndrome: the Cardiovascular Risk in Young Finns Study
    Noora Mattsson
    The Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Finland
    Eur Heart J 29:784-91. 2008
    ..To study the relations between the metabolic syndrome (MS) and subclinical atherosclerosis in young adults...
  76. ncbi Smoking, fasting serum insulin, and obesity are the predictors of carotid atherosclerosis in relatively young subjects
    Takayuki Naya
    Department of Cardiorenal and Cerebrovascular Medicine, Division of Stroke, Kagawa University School of Medicine, Kagawa, Japan
    Angiology 58:677-84. 2007
    ..All subjects underwent carotid ultrasound examinations to determine maximal common carotid artery intima media thickness...
  77. ncbi Heritability of carotid artery distensibility in Hispanics: the Northern Manhattan Family Study
    Suh Hang Hank Juo
    Genome Center, Department of Epidemiology, Columbia University, New York, NY 10032, USA
    Stroke 36:2357-61. 2005
    ..The importance of the genetic contribution to variation in distensibility is largely unknown. The purpose of this study was to estimate heritability of carotid distensibility...
  78. ncbi The relationship between carotid and coronary atherosclerotic damage in dialysis patients
    F Fabbian
    Department of Nephrology, St Anna Hospital, Ferrara Italy
    Int J Artif Organs 30:315-20. 2007
    ..Data relating carotid ultrasound (CU) to atherosclerotic damage evaluated by coronary angiography in hemodialysis patients are scarce...
  79. ncbi The evaluation of carotid intima-media thickness in children with familial Mediterranean fever
    Harun Peru
    Department of Pediatric Nephrology, Meram Medical Faculty, Selcuk University, 42080 Konya, Turkey
    Clin Rheumatol 27:689-94. 2008
    ..Mean C-reactive protein (CRP), serum amyloid-A (SAA), homocysteine (Hcy), lipoprotein-a (Lp-a), and common carotid artery intima-media thickness (CCA-IMT) were 10.75 +/- 15.29 vs 4.03 +/- 1.20, 23.22 +/- 41.94 vs 3.53 +/- 1...
  80. ncbi Polymorphisms in MMP family and TIMP genes and carotid artery intima-media thickness
    Christine Armstrong
    Centre for Clinical Neuroscience, St George s University of London, Cranmer Terrace, Tooting, London, UK
    Stroke 38:2895-9. 2007
    ..We have therefore sought to address this issue in a large, well-phenotyped community population to assess the effect of a number of polymorphisms in both MMP and TIMP genes on carotid artery intima-media thickness (IMT)...
  81. ncbi Effect of antihypertensive therapy on progression of carotid intima-media thickness in patients with type 2 diabetes mellitus
    Ling Zheng
    Department of Neurology, Atherosclerosis Research Unit, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Am J Cardiol 99:956-60. 2007
    ..The antiatherogenic effect of antihypertensive agents, including BP normalization and possible direct vascular wall protection, can be detected by CIMT progression using B-mode ultrasound in patients with DM...
  82. ncbi Relation of subepicardial adipose tissue to carotid intima-media thickness in patients with human immunodeficiency virus
    Gianluca Iacobellis
    Cardiovascular Obesity Research and Management at the Michael G deGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada
    Am J Cardiol 99:1470-2. 2007
    ..81, p <0.01). In conclusion, this study suggests, for the first time, that epicardial adipose tissue, an index of cardiac adiposity, may be significantly related to subclinical atherosclerosis in HIV-infected patients...
  83. ncbi Relevance of common carotid intima-media thickness and carotid plaque as risk factors for ischemic stroke in patients with type 2 diabetes mellitus
    E J Lee
    Department of Radiology, Myongji Hospital, Kwandong University, College of Medicine, Koyang, Korea
    AJNR Am J Neuroradiol 28:916-9. 2007
    An increase in the common carotid artery intima-media thickness (CCA-IMT) is generally considered an early marker of atherosclerosis...
  84. ncbi Renal resistive index and cardiovascular organ damage in a large population of hypertensive patients
    M A Tedesco
    Division of Cardiology, Second University of Naples, Monaldi Hospital, Naples, Italy
    J Hum Hypertens 21:291-6. 2007
    ..The evaluation of RRI could predict the presence of early CV damage and provide an accurate estimate of overall risk...
  85. ncbi Carotid artery intima media thickness, plaque and Framingham cardiovascular score in Asia, Africa/Middle East and Latin America: the PARC-AALA study
    Pierre Jean Touboul
    Department of Neurology and Stroke Centre, Denis Diderot University Paris VII, 48 Rue R Huchard, Paris 75018, France
    Int J Cardiovasc Imaging 23:557-67. 2007
    ..Africa/ Middle East and Latin America) study was designed to evaluate the correlation between intima-media thickness of the common carotid artery (CCAIMT), carotid plaque and absolute cardiovascular risk in a multi-ethnic population.
  86. ncbi Can measurement of the intima-media thickness of the carotid artery improve the diagnostic value of exercise stress tests?
    Hilde Heuten
    Department of Cardiology, University Hospital of Antwerp, Edegem, Belgium
    Acta Cardiol 61:501-5. 2006
    ..The aim of this study is to evaluate whether measurements of intima-media thickness can improve the diagnostic value of stress ECG in the detection of coronary artery disease...
  87. ncbi Combination of multiple genetic risk factors is synergistically associated with carotid atherosclerosis in Japanese subjects with type 2 diabetes
    Yoshimitsu Yamasaki
    Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita City, Osaka 565 0871, Japan
    Diabetes Care 29:2445-51. 2006
    ..However, the synergistic effects of SNPs have not been evaluated in detail...
  88. ncbi Carotid intima-media thickness in confirmed prehypertensive subjects: predictors and progression
    Romana Femia
    Department of Internal Medicine and Metabolism Unit of the C N R Institute of Clinical Physiology
    Arterioscler Thromb Vasc Biol 27:2244-9. 2007
    ....
  89. ncbi Independent association of matrix metalloproteinase-10, cardiovascular risk factors and subclinical atherosclerosis
    J Orbe
    Laboratory of Atherosclerosis, Division of Cardiovascular Sciences, Center for Applied Medical Research, Pamplona, Spain
    J Thromb Haemost 5:91-7. 2007
    ..Whether MMP-10 is associated with the severity of atherosclerosis remains to be determined. This study examines the relationship of systemic MMP-10 levels with atherosclerotic risk factors and subclinical atherosclerosis...
  90. ncbi Flow-mediated vasodilatation of the brachial artery and intima-media thickness of carotid artery in never-treated subjects
    C Irace
    Department of Experimental and Clinical Medicine, Magna Graecia University of Catanzaro, Catanzaro, Italy
    Int Angiol 25:274-9. 2006
    ..The present study investigated the relationship between FMD and IMT and carotid atherosclerosis in never treated subjects...
  91. ncbi Consumption of fruit and berries is inversely associated with carotid atherosclerosis in elderly men
    I Ellingsen
    Department of Preventive Cardiology, Ulleval University Hospital, N 0047 Oslo, Norway
    Br J Nutr 99:674-81. 2008
    ..5 % adjusted difference in mean IMT. These findings suggest that consumption of fruit and berries may be protective against carotid atherosclerosis in elderly men at high risk of CVD...
  92. ncbi Endothelial dysfunction, intima-media thickness and coronary reserve in relation to risk factors and Framingham score in patients without clinical atherosclerosis
    Raquel Campuzano
    , Hospital Universitario de Guadalajara, Spain
    J Hypertens 24:1581-8. 2006
    ..ultrasound was used to analyse endothelium-dependent vascular dilation in the brachial artery, IMT in the common carotid artery and CFR in the left anterior artery...
  93. ncbi Relationship between serum uric acid concentration, metabolic syndrome and carotid atherosclerosis
    Ryuichi Kawamoto
    Department of Internal Medicine, Seiyo Municipal Nomura Hospital, Seiyo
    Intern Med 45:605-14. 2006
    ..In men without metabolic syndrome, SUA was found to be an independent risk factor for incidence of carotid atherosclerosis...
  94. ncbi Cytokine polymorphisms associated with carotid intima-media thickness in stroke patients
    David Brenner
    Department of Neurology and Stroke Centre, Bichat University Hospital, Denis Diderot University and Medical School, Paris, France
    Stroke 37:1691-6. 2006
    ..Evidence exists that carotid IMT is heritable, and genetic studies can provide clues in the pathogenesis of atherosclerosis...
  95. ncbi Increased intima-media thickness after early-onset preeclampsia
    Judith Blaauw
    Department of Obstetrics and Gynecology, University Medical Center Groningen, Groningen, The Netherlands
    Obstet Gynecol 107:1345-51. 2006
    ..An increase in IMT of the common carotid artery between the normal pregnancy and the nulliparous group was observed, which became significant after ..
  96. ncbi Association between risk factors and carotid enlargement
    Ryuichi Kawamoto
    Department of Internal Medicine, Nomura Municipal Hospital, Ehime
    Intern Med 45:503-9. 2006
    ..PATIENTS AND METHODS: We evaluated the diameter and intima-media thickness (IMT) of common carotid artery (CCA) by ultrasonography in 351 men aged 70.3 (range, 14-97) years and 474 women aged 75...
  97. ncbi Augmentation index and carotid intima-media thickness are differently related to age, C-reactive protein and oxidized low-density lipoprotein
    Priit Kampus
    Department of Cardiology, National and European Centre of Excellence of Molecular and Clinical Medicine, University of Tartu, Tartu, Estonia
    J Hypertens 25:819-25. 2007
    ..The aim of this study was to evaluate the relationship between age, inflammatory and oxidative stress-related markers with functional and structural changes of the arteries in asymptomatic persons...
  98. ncbi Association of obesity and central fat distribution with carotid artery wall thickening in middle-aged women
    Mario De Michele
    Departments of Clinical and Experimental Medicine, Federico II, University, Naples, Italy
    Stroke 33:2923-8. 2002
    ..In the present analysis, we evaluated whether common carotid intima-media thickness (IMT) and area, 2 markers of preclinical atherosclerosis, were increased in obese subjects...
  99. ncbi Relationship between cardio-ankle vascular index (CAVI) and carotid atherosclerosis in patients with essential hypertension
    Takafumi Okura
    Department of Integrated Medicine and Informatics, Ehime University Graduate School of Medicine, Toon, Japan
    Hypertens Res 30:335-40. 2007
    ..492, r<0.0001) were independent determinants of CAVI. These results suggest that CAVI is a useful clinical marker for evaluating atherosclerosis and arteriolosclerosis in patients with essential hypertension...
  100. ncbi Relationship between C reactive protein and pulse pressure is not mediated by atherosclerosis or aortic stiffness
    Jacques Amar
    Department of Internal Medicine and Arterial Hypertension, CHU Purpan, Toulouse, France
    J Hypertens 22:349-55. 2004
    ..CONCLUSIONS: The results of this study demonstrate that changes in arterial structure and in arterial stiffness are not confounding factors in the relationship between PP and CRP...
  101. ncbi Is carotid artery intima-media thickening a reliable marker of early atherosclerosis?
    Jamil Mayet
    Peart Rose Waller Centre for Circulatory Health, St Mary s Hospital, Imperial College School of Medicine, London, UK
    J Cardiovasc Risk 9:77-81. 2002
    ..This is an important observation, since it suggests that an increased carotid IMT cannot be relied on solely as a marker of early atherosclerosis...

Research Grants69

  1. Middle Cerebral and Common Artery Occlusion and Poststroke Epilepsy
    Kevin Kelly; Fiscal Year: 2007
    ..in our laboratory indicate that transient (3 hr) unilateral (left-sided) middle cerebral artery (MCA) and common carotid artery (CCA) occlusion (MCA/CCAO) results in poststroke epilepsy less frequently in 4 mo old male Fischer 344 (..
  2. Circuit Weight Training and Blood Pressure Regulation in Prehypertension
    William Cooke; Fiscal Year: 2007
    ..4) Using bidirectional transcutaneous Doppler ultrasound probes, pulse waves velocities between the left common carotid artery and the left femoral artery, and the left femoral artery and the superior dorsalis pedis artery will be ..
  3. Jun Kinase Signaling and Apoptosis in Ischemia Stroke
    Chia Yi Kuan; Fiscal Year: 2006
    ..With this in mind, a mouse model of global based on unilateral common carotid artery occlusion followed by hypoxia was created...
  4. NITRIC OXIDE IN ATHEROGENESIS AND ARTERIAL RELAXATION
    Richard Cohen; Fiscal Year: 1999
    ..to destruction, and mechanism of action of nitric oxide in the thoracic aorta compared with the common carotid artery might partially explain differences in susceptibility to atherosclerosis...
  5. Laser Catheter for Dethrombosis of Arterial Occlusion
    Brant Watson; Fiscal Year: 2005
    ..containing an ultraviolet (UV) light-conducting glass optical fiber, which will be used to remove, from a common carotid artery (CCA) of a rat, an occlusive blood clot (thrombus) and to demonstrate, in particular, the effectiveness of ..
  6. Phytoestrogens and Progression of Atherosclerosis
    HOWARD HODIS; Fiscal Year: 2007
    ..primary end point will be the progression of subclinical atherosclerosis measured as the rate of change in common carotid artery intima-media thickness in computer image processed B-mode ultrasonograms, a well-established noninvasive ..
  7. Intracranial Aneurysm Pathogenesis-Roles of Vascular Remodeling and Inflammation
    Tomoki Hashimoto; Fiscal Year: 2010
    ..Using a rodent common carotid artery flow augmentation model, we will demonstrate that depletion of neutrophils and/or macrophages reduces flow-..
  8. Intracranial Aneurysm Pathogenesis-Roles of Vascular Remodeling and Inflammation
    Tomoki Hashimoto; Fiscal Year: 2007
    ..Using a rodent common carotid artery flow augmentation model, we will demonstrate that depletion of neutrophils and/or macrophages reduces flow-..
  9. IMPORTANCE OF THE BLOOD-BRAIN BARRIER IN STROKE
    W Dietrich; Fiscal Year: 1993
    ..of embolic stroke on the microvasculature and brain parenchyma will be first investigated following common carotid artery thrombosis (CCA)...
  10. Prevention of Diabetes in Obese Hispanic Adolescents
    Martha Cruz; Fiscal Year: 2005
    ..risk factors (lipids, lipoproteins, blood pressure) and atherosclerosis (via intima media thickness of the common carotid artery and arterial stiffness) in Hispanic youth, before and after 12 weeks of treatment (30 mg/day) with ..
  11. Genetic analysis of neointimal hyperplasia
    Weibin Shi; Fiscal Year: 2009
    ..together with male F1 and two parental strains, will be subject to endothelial denudation of the left common carotid artery. Neointimal thickening will be quantitated by light microscopy...
  12. PATHOPHYSIOLOGY OF THROMBOEMBOLIC STROKE
    W Dietrich; Fiscal Year: 2003
    DESCRIPTION (adapted from the Applicant's Abstract): Transient distal platelet accumulation after common carotid artery thrombosis (CCAT) leads to structural, hemodynamic and molecular events-that may be expected to influence the ..
  13. Arterial baroreceptor unloading causes hypertension
    TERRY THRASHER; Fiscal Year: 2005
    ..In this model, ligation of the common carotid artery proximal to the innervated carotid sinus produces a significant and sustained increase in systemic ..
  14. PATHOPHYSIOLOGY OF THROMBOEMBOLIC STROKE
    W Dietrich; Fiscal Year: 1999
    ..barrier, hemodynamic and neurochemi calabnormalities generated by photochemically induced nonocclusive common carotid artery thrombosis (CCAT) in rats...
  15. Improving Vascular Measures of Cardiovascular Disease
    Marsha Eigenbrodt; Fiscal Year: 2005
    ..Two inexpensive, non-invasive measures include B-mode ultrasound evaluation of common carotid artery intima medial thickness (IMT) and microvascular abnormalities on retinal photographs...
  16. Genetic analysis of neointimal hyperplasia
    Weibin Shi; Fiscal Year: 2007
    ..together with male F1 and two parental strains, will be subject to endothelial denudation of the left common carotid artery. Neointimal thickening will be quantitated by light microscopy...
  17. n-Stent Stenosis Model in Type 2 Diabetic Rats
    Tiangen Wu; Fiscal Year: 2005
    ..Stents will be deployed in the left common carotid artery of two cohorts of twelve rats each...
  18. Mechanisms of endothelial repair after vascular injury
    Zvonimir S Katusic; Fiscal Year: 2010
    ..Established models of wire-induced injury of common carotid artery and hind limb ischemia in nude mice will be employed to determine the role of PGI2 derived from EPCs in ..