Genomes and Genes
Summary: The aorta from the DIAPHRAGM to the bifurcation into the right and left common iliac arteries.
Publications258 found, 100 shown here
- Multidetector row CT angiography of the abdominal aorta and lower extremities in patients with peripheral arterial occlusive disease: diagnostic accuracy and interobserver agreementMaurizio Romano
Department of Surgery, University Federico II, 5, Via Pansini, 80131 Naples, Italy
Eur J Radiol 50:303-8. 2004To evaluate the accuracy of four channel multidetector row CT angiography (MDCTA) of the abdominal aorta and lower extremities arteries compared with digital subtraction angiography (DSA).
- Follow-up of patients with previous vascular interventions: role of multidetector row computed tomographic angiography of the abdominal aorta and lower extremitiesM Romano
J Cardiovasc Surg (Torino) 45:89-91. 2004
- Finite element modeling of three-dimensional pulsatile flow in the abdominal aorta: relevance to atherosclerosisC A Taylor
Department of Surgery, Stanford University, CA, USA
Ann Biomed Eng 26:975-87. 1998The infrarenal abdominal aorta is particularly prone to atherosclerotic plaque formation while the thoracic aorta is relatively resistant...
- Rapid dilation of the abdominal aorta during infusion of angiotensin II detected by noninvasive high-frequency ultrasonographyChiara Barisione
Cardiovascular Research Center, University of Kentucky, Lexington, KY 40536, USA
J Vasc Surg 44:372-6. 2006..This system had 100% accuracy in detecting AngII-induced AAAs in vivo, with intrauser and interuser variation coefficients of less than 10% for quantification of the aortic lumen diameter...
- Compositional and structural alterations of chondroitin and dermatan sulfates during the progression of atherosclerosis and aneurysmal dilatation of the human abdominal aortaAchilleas D Theocharis
Laboratory of Biochemistry, Section of Organic Chemistry, Biochemistry and Natural Products, Department of Chemistry, University of Patras, 26110 Patras, Greece
Biochimie 84:667-74. 2002..and dermatan sulfate (DS)--during the progression of atherosclerosis and aneurysmal dilatation of the human abdominal aorta. The concentration of CS was increased 24% (p < or = 0...
- Aortic calcification in haemodialysis patients with diabetes mellitusHiromichi Taniwaki
Inoue Hospital, Department of Nephrology, Osaka City University Graduate School of Medicine, 1 4 3, Asahi machi, Abeno Ku, Osaka 545 8585, Japan
Nephrol Dial Transplant 20:2472-8. 2005..This study examined the risk factors of aortic calcification in a large number of haemodialysis patients, and compared risk factors between diabetic and non-diabetic patients...
- Ethnic-specific risks for atherosclerotic calcification of the thoracic and abdominal aorta (from the Multi-Ethnic Study of Atherosclerosis)Matthew A Allison
University of California, San Diego, La Jolla, California, USA
Am J Cardiol 104:812-7. 2009..In conclusion, compared to whites, African-Americans and Hispanics, but not Chinese, have evidence of less atherosclerosis in the thoracic and abdominal aortas, which does not appear to be accounted for by traditional CVD risk factors...
- 3-D numerical simulation of blood flow through models of the human aortaL Morris
Centre for Applied Biomedical Engineering Research, Dept Mechanical and Aeronautical Eng and Material and Surface Science Institute, University of Limerick, Castletroy, Limerick, Ireland
J Biomech Eng 127:767-75. 2005..Flow patterns obtained from transient 3-D computational fluid dynamics are influenced by different reconstruction methods and the pulsatility of the flow. Caution is required when analyzing models based on CT scans...
- Quantitative determination of age-related geometric changes in the normal abdominal aortaD Fleischmann
Department of Radiology, Stanford University School of Medicine, CA 94305-5105, USA
J Vasc Surg 33:97-105. 2001..diameter measurements were obtained at 1-mm intervals along the automatically calculated central axis of the abdominal aorta. The aorta was subdivided into six consecutive anatomic segments (supraceliac, supramesenteric, suprarenal, ..
- The anterior visceral branches of the abdominal aorta and their relationship to the renal arteriesNeil Pennington
School of Biomedical Sciences, University of Leeds, Leeds, LS2 9JT, UK
Surg Radiol Anat 27:395-403. 2005Variations in the anatomy of the abdominal aorta and its branches are of interest as vessel geometry not only determines flow dynamics, but is also crucial in the pathogenesis of vascular disease...
- A decoupled fluid structure approach for estimating wall stress in abdominal aortic aneurysmsYannis Papaharilaou
Institute of Applied and Computational Mathematics, Foundation for Research and Technology Hellas, P O Box 1385, 71110 Heraklion, Crete, Greece
J Biomech 40:367-77. 2007..5% compared to the proposed decoupled fluid structure approach. Furthermore, the decoupled approach provides potentially useful information on the nature of the aneurysmal sac flow...
- A multicentre study of abdominal aorta diameters in a Turkish populationN Sariosmanoglu
Dokuz Eylul University Medical School, Izmir, Turkey
J Int Med Res 30:1-8. 2002..Considering the significant number of patients with aneurysmal dilatation of the aorta in the elderly population, we believe it would be prudent to evaluate the aorta in all patients undergoing abdominal ultrasonographic examination...
- Ginsenoside Rg(1) inhibits rat left ventricular hypertrophy induced by abdominal aorta coarctation: involvement of calcineurin and mitogen-activated protein kinase signalingsJiang Deng
Department of Pharmacology, Zunyi Medical College, Zunyi, Guizhou, PR China
Eur J Pharmacol 608:42-7. 2009..The rat left ventricular hypertrophy was induced by abdominal aorta coarctation and Rg(1) (3.75, 7.5 and 15 mg/kg/day) was given the day after surgery for 21 consecutive days...
- Abdominal aorta screening during transthoracic echocardiographyFarideh Roshanali
Day General Hospital, Tehran, Iran
Echocardiography 24:685-8. 2007..This modified examination is arguably a simple, safe, quick, and accurate way to identify patients with abdominal aortic aneurysm (AAA)...
- Hemodynamic relationships among upper-abdominal aorta and femoral arteries: basis for measurement of arterial blood flow to abdominal-pelvic organsTakuya Osada
Department of Sports Medicine for Health Promotion, Tokyo Medical University, Tokyo, Japan
Med Sci Monit 15:CR332-40. 2009..subtracting BF in the "peripheral" bilateral limb left/right-femoral arteries (FA) from the "central" upper abdominal aorta (Ao) above the celiac trunk according to the formula: BFAP = BFAo-both BFFAs...
- Fluid-structure interaction within realistic three-dimensional models of the aneurysmatic aorta as a guidance to assess the risk of rupture of the aneurysmE S Di Martino
Department of Bioengineering, Politecnico of Milano, Milan, Italy
Med Eng Phys 23:647-55. 2001..A proven clinical efficacy may promote the method as a tool to determine factual aneurysm risk of rupture and aid the surgeon to refer elective surgery patients...
- Bone loss and the progression of abdominal aortic calcification over a 25 year period: the Framingham Heart StudyD P Kiel
Hebrew Rehabilitation Center for Aged Research and Training Institute and Harvard Medical School Division on Aging, Boston, MA, USA
Calcif Tissue Int 68:271-6. 2001..cohort of older men and women, we tested the hypothesis that the progression of vascular calcification of the abdominal aorta should be greatest in those individuals with the greatest amount of bone loss...
- Blood flow and structure interactions in a stented abdominal aortic aneurysm modelZhonghua Li
Department of Mechanical and Aerospace Engineering, North Carolina State University, Campus Box 7910, 3198 Broughton Hall, Raleigh, NC 27695 7910, USA
Med Eng Phys 27:369-82. 2005..The time-varying drag force on the EVG exerted by physiological blood flow is unavoidable, where for patients with severe hypertension the risk of EVG migration is very high...
- The effects of aneurysm on the biaxial mechanical behavior of human abdominal aortaJonathan P Vande Geest
Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15213, USA
J Biomech 39:1324-34. 2006..It was concluded that aneurysmal degeneration of the abdominal aorta is associated with an increase in mechanical anisotropy, with preferential stiffening in the circumferential ..
- Induction of neuronal and inducible nitric oxide synthase in the motoneurons of spinal cord following transient abdominal aorta occlusion in ratsY Zhou
Department of Experimental Surgery, Singapore General Hospital, 169608, Singapore
J Surg Res 87:185-93. 1999..nitric oxide synthase (n-NOS and i-NOS) and nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d) in the motoneurons of the lumbosacral spinal cord was examined in a rat model with transient abdominal aorta (TAA) occlusion.
- The serum level of bone-specific alkaline phosphatase activity is associated with aortic calcification in osteoporosis patientsKousuke Iba
Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, South 1, West 16, Chuo Ku, Sapporo, Japan
J Bone Miner Metab 22:594-6. 2004..Bone-specific alkaline phosphatase is the most important marker for osteoblast differentiation; furthermore, the serum level of its activity may reflect the process of calcification of the aorta in osteoporosis patients...
- In vivo assessment of blood flow patterns in abdominal aorta of mice with MRI: implications for AAA localizationSmbat Amirbekian
Department of Radiology, Emory University School of Medicine, Georgia Institute of Technology, Atlanta, Georgia 30322, USA
Am J Physiol Heart Circ Physiol 297:H1290-5. 2009..We measured blood flow in the suprarenal and infrarenal abdominal aorta of 18 wild-type C57BL/6J mice and 15 apolipoprotein E (apoE)-/- mice...
- Stiffness of the abdominal aorta in beta-thalassemia major patients related with body iron loadZulal Ulger
Department of Pediatric Cardiology, Ege University Hospital, Bornova Izmir, Turkey
J Pediatr Hematol Oncol 28:647-52. 2006..We evaluated whether the abdominal aortic stiffness was altered in the patients with beta-thalassemia major in relation with body iron load...
- The effect of asymmetry in abdominal aortic aneurysms under physiologically realistic pulsatile flow conditionsE A Finol
Institute for Complex Engineered Systems, Faculty, Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USA
J Biomech Eng 125:207-17. 2003..The effect of asymmetry in hypothetically shaped AAAs is to increase the maximum wall shear stress at peak flow and to induce the appearance of secondary flows in late diastole...
- Multiplicity of the variations in ventral branches of abdominal aortaHulya Ucerler
Department of Anatomy, Medicine Faculty, Ege University, Bornova, Izmir, Turkey
Ital J Anat Embryol 111:15-22. 2006Numerous variations of the ventral branches of the abdominal aorta were observed during routine dissection of the abdominal region in a 63-year-old male cadaver in the Department of Anatomy at Ege University Medicine Faculty...
- Aneurysmal and occlusive atherosclerosis of the human abdominal aortaC Xu
Department of Surgery, Stanford University, CA, USA
J Vasc Surg 33:91-6. 2001..The purpose of this study was to assess atherosclerotic plaque deposition and aortic wall responses in the abdominal aorta in relation to the development of aneurysmal and occlusive disease in the infrarenal aorta...
- Effect of thrombus on abdominal aortic aneurysm wall dilation and stressM J Thubrikar
Heineman Medical Research Laboratories, Carolinas Heart Institute, Carolinas Medical Center, Charlotte, NC 28203, USA
J Cardiovasc Surg (Torino) 44:67-77. 2003..Our goal is to understand how a mural thrombus may influence the pressure transmitted to and the dilation experienced by the abdominal aortic aneurysm (AAA) wall...
- Lumbar disc degeneration and atherosclerosis of the abdominal aortaL I Kauppila
Department of Forensic Medicine, University of Helsinki, Finland
Spine (Phila Pa 1976) 19:923-9. 1994STUDY DESIGN. This study analyzed the relationship of disc degeneration to atherosclerotic changes in the abdominal aorta and stenosis of the ostia of the lumbar and middle sacral arteries, 86 plain radiographs of lumbosacral spines, and ..
- Expression and localization of vascular endothelial growth factor in normal abdominal aorta and abdominal aortic aneurysmT Nishibe
Department of Cardiovascular Surgery, Tokyo Medical University Hachioji Medical Center, Hachioji, Japan
Int Angiol 29:260-5. 2010..We analyzed the expression and localization of VEGF in human abdominal aortic aneurysms compared to normal human aorta..
- Presence of abdominal aortic calcification is significantly associated with all-cause and cardiovascular mortality in maintenance hemodialysis patientsSenji Okuno
Kidney Center, Shirasagi Hospital, Osaka, Japan
Am J Kidney Dis 49:417-25. 2007....
- Studies on the mechanisms underlying beta-adrenoceptor-mediated relaxation of rat abdominal aortaMayumi Matsushita
Department of Chemical Pharmacology, Toho University School of Pharmaceutical Sciences, Chiba, Japan
J Smooth Muscle Res 42:217-25. 2006..Mechanisms underlying beta-adrenoceptor (beta-AR)-mediated vascular relaxation were studied in the isolated rat abdominal aorta. In the endothelium-denuded helical preparations, a non-selective beta-AR agonist isoprenaline elicited a ..
- Age dependency of stiffness of the abdominal aorta and the mechanical properties of the aorta in Kawasaki disease in childrenM Okubo
Department of Pediatrics, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan
Pediatr Cardiol 22:198-203. 2001..This study had two purposes: to assess the stiffness of the abdominal aorta by using two-dimensional echocardiography (2DE) in healthy neonates, children, and adults and to assess ..
- Abdominal aorta: evaluation with dual-source dual-energy multidetector CT after endovascular repair of aneurysms--initial observationsHersh Chandarana
Department of Radiology, New York University Medical Center, Tisch Hospital, New York, NY 10016, USA
Radiology 249:692-700. 2008..To evaluate the possible radiation dose reduction facilitated by using dual-energy (DE) multidetector computed tomography (CT) after endovascular repair of abdominal aortic aneurysms (AAAs)...
- A possible association between coronary plaque instability and complex plaques in abdominal aortaYukihiko Momiyama
National Defense Medical College, Saitama 359 8513, Japan
Arterioscler Thromb Vasc Biol 26:903-9. 2006..Complex carotid plaques were reported to be prevalent in unstable angina. We investigated associations between coronary plaque instability, such as MI and angiographic complex coronary lesions, and aortic plaques...
- The relationship between wall shear stress distributions and intimal thickening in the human abdominal aortaMichael Bonert
Department of Mechanical and Industrial Engineering, University of Toronto, Canada
Biomed Eng Online 2:18. 2003The goal of this work was to determine wall shear stress (WSS) patterns in the human abdominal aorta and to compare these patterns to measurements of intimal thickness (IT) from autopsy samples.
- Measuring the abdominal aorta with ultrasonography and computed tomography - difference and variabilityA Wanhainen
Department of Surgery Ornsköldsvik, County Hospital, Sweden
Eur J Vasc Endovasc Surg 24:428-34. 2002..The aim of this study was to estimate the agreement between ultrasonography (US) and computed tomography (CT) in the measurement of aortic diameter in subjects with and without abdominal aortic aneurysms (AAA)...
- Flow-induced wall shear stress in abdominal aortic aneurysms: Part II--pulsatile flow hemodynamicsEnder A Finol
Mechanical Engineering, Biomedical and Health Engineering, and institute for Complex Engineered Systems, Carnegie Mellon University, Pittsburgh, PA, USA
Comput Methods Biomech Biomed Engin 5:319-28. 2002..A comparison between numerical predictions for steady and pulsatile flow is presented, illustrating the importance of considering time-dependent flow for the evaluation of hemodynamic indicators...
- Towards a noninvasive method for determination of patient-specific wall strength distribution in abdominal aortic aneurysmsJonathan P Vande Geest
Department of Surgery, Division of Vascular Surgery, Pittsburgh, PA 15219, USA
Ann Biomed Eng 34:1098-106. 2006..Coupling this model with our stress analysis technique may provide a more accurate means to estimate patient-specific rupture potential of AAA...
- Chronic periaortitis: a spectrum of diseasesAugusto Vaglio
Department of Clinical Medicine, Nephrology and Health Science, University of Parma, Parma, Italy
Curr Opin Rheumatol 17:34-40. 2005..This review analyses the different aspects of the disease and highlights evolving concepts concerning its pathogenesis, diagnosis, and management...
- Atherosclerotic enlargement of the human abdominal aortaC K Zarins
Department of Surgery, Division of Vascular Surgery, Suite H 3600, Stanford University Medical Center, Stanford, CA 94305 5642, USA
Atherosclerosis 155:157-64. 2001Aortic aneurysms usually develop in the atherosclerosis prone infrarenal abdominal aorta. To assess the role of atherosclerosis in aortic enlargement, we studied the relation between plaque formation and aortic size in 30 pressure-fixed ..
- Flow-induced wall shear stress in abdominal aortic aneurysms: Part I--steady flow hemodynamicsEnder A Finol
Mechanical Engineering, Biomedical and Health Engineering, and institute for Complex Engineered Systems, Carnegie Mellon University, Pittsburgh, PA, USA
Comput Methods Biomech Biomed Engin 5:309-18. 2002..The temporal distribution of hemodynamic stresses in pulsatile flow and their physical implications in AAA rupture are discussed in Part II of this paper...
- Iodixanol in multidetector-row computed tomography angiography (MDCTA): diagnostic accuracy for abdominal aorta and abdominal aortic major-branch diseases using four-, eight- and 16-detector-row CT scannersM Nonent
Department of Radiology and Groupe d Etude de la Thrombose de Bretagne Occidentale, GETBO, University Hospital, 29609 Brest Cedex, France
Acta Radiol 48:48-58. 2007..iodixanol-enhanced multidetector-row computed tomography angiography (MDCTA) with digital subtraction angiography (DSA), perioperative angiography, or surgical findings in the evaluation of the abdominal aorta and its main branches.
- Atherogenesis in mice does not require CD40 ligand from bone marrow-derived cellsUdo Bavendiek
Donald W Reynolds Cardiovascular Clinical Research Center, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass02115, USA
Arterioscler Thromb Vasc Biol 25:1244-9. 2005....
- Cross-sectional imaging of acute diseases of the abdominal aorta and its branchesJorge A Soto
Department of Radiology, Boston University Medical Center, 88 East Newton Street, Boston, MA 02118, USA
Emerg Radiol 11:29-36. 2004
- Hypoplasia and fibromuscular dysplasia of infrarenal abdominal aorta with downstream aneurysm: case report and review of the literatureAttilio Odero
Division of Vascular Surgery, IRCCS Policlinico San Matteo Foundation and University of Pavia, Pavia, Italy
J Vasc Surg 48:1589-92. 2008..Exceptionally, it has been described in the abdominal aorta. Aortic hypoplasia is a tubular narrowing of a long segment of the aorta and is a rare congenital defect, ..
- High-pitch dual-source CT angiography of the thoracic and abdominal aorta: is simultaneous coronary artery assessment possible?Robert Goetti
Institute of Diagnostic Radiology, University Hospital Zurich, Raemistrasse 100, CH 8091 Zurich, Switzerland
AJR Am J Roentgenol 194:938-44. 2010....
- Different patterns of atherosclerotic remodeling in the thoracic and abdominal aortaLuiz Alberto Benvenuti
Laboratory of Pathology, Heart Institute, Hospital das Clinicas, University of Sao Paulo, Brazil
Clinics (Sao Paulo) 60:355-60. 2005..To investigate the relationship between the vascular diameter and the extent and histologic characteristics of atherosclerosis in the thoracic and abdominal aortas of patients who died of atherosclerotic disease...
- Anomalies of the abdominal aorta in Williams-Beuren syndrome--another cause of arterial hypertensionC Rose
Department of Paediatric Cardiology, University Hospital Gottingen, Germany
Eur J Pediatr 160:655-8. 2001..This study presents the pattern of stenotic lesions of the abdominal aorta and the incidence of arterial hypertension...
- Pulsatile flow in fusiform models of abdoiminal aortic aneurysms: flow fields, velocity patterns and flow-induced wall stressesRobert A Peattie
Department of Chemical Engineering, Oregon State University, Corvallis, OR 97331, USA
J Biomech Eng 126:438-46. 2004..Concomitantly, increased turbulence may contribute significantly to wall stress magnitude and thereby to risk of rupture...
- Catastrophic presentation of atrial myxoma with total occlusion of abdominal aortaSumit Yadav
Department of Cardiothoracic Surgery, The Townsville Hospital, Doulas, Townsville, QLD, Australia
Interact Cardiovasc Thorac Surg 9:913-5. 2009..We report a patient with cardiac myxoma presenting with multi-organ embolism including saddle embolism of the aorta in a previously healthy female...
- Geometric variability of the abdominal aorta and its major peripheral branchesPadraig M O'Flynn
Department of Mechanical and Biomedical Engineering, National University of Ireland, and University College Hospital, Galway, University Road, Galway, Ireland
Ann Biomed Eng 38:824-40. 2010..this study was to quantitatively evaluate the intersubject variability of 3D branching and curvature of the abdominal aorta and its major peripheral arteries...
- Influence of normovolemic anemia on Doppler characteristics of the abdominal aorta and splanchnic vessels in BeaglesLee M Koma
Section of Diagnostic Imaging, Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Private Bag X04 Onderstepoort, 0110, Republic of South Africa
Am J Vet Res 66:187-95. 2005To ultrasonographically evaluate hemodynamics in the abdominal aorta (AAo) and splanchnic vessels in dogs with experimentally induced normovolemic anemia.
- Inhibitory effect of Ginkgo biloba extract on hyperhomocysteinemia-induced intimal thickening in rabbit abdominal aorta after balloon injuryFenye Liu
Department of Traditional Chinese Medicine, Qilu Hospital Affiliated to Shandong University, Jinan 250012, Shandong, PR China
Phytother Res 22:506-10. 2008..to investigate whether GBE could attenuate the Hhcy-induced intimal thickening after balloon injury in rabbit abdominal aorta. It was observed in this study that GBE could decrease the neointima area (NA) and the ratio of the neointima ..
- Contrast-enhanced peripheral MR angiography from the abdominal aorta to the pedal arteries: combined dynamic two-dimensional and bolus-chase three-dimensional acquisitionsY Wang
Department of Radiology, Weill Medical College of Cornell University, 515 E 71st Street, New York City, NY 10021, USA
Invest Radiol 36:170-7. 2001Wang Y, Winchester PA, Khilnani NM, et al. Contrast-enhanced peripheral MR angiography from the abdominal aorta to the pedal arteries: Combined dynamic two-dimensional and bolus-chase three-dimensional acquisitions...
- Mycotic aneurysms of the thoracic and abdominal aorta and iliac arteries: experience with anatomic and extra-anatomic repair in 33 casesB T Müller
Department of Vascular Surgery and Kidney Transplantation, Heinrich Heine University, Dusseldorf, Germany
J Vasc Surg 33:106-13. 2001..The aim of our study was to find out whether any progress could be achieved in a single center over a long time period (18 years) through use of surgical techniques and antiseptic adjuncts...
- A case of transradial carotid stenting in a patient with total occlusion of distal abdominal aortaByung Su Yoo
Department of Cardiology, Wonju College of Medicine, Yonsei University, Wonju, Korea
Catheter Cardiovasc Interv 56:243-5. 2002..carotid stenosis in which carotid stenting was performed via the radial artery due to total occlusion of distal abdominal aorta. The radial approach offers a potential alternative in cases in which the femoral approach is problematic.
- Rat abdominal aorta stenting: a new and reliable small animal model for in-stent restenosisBas Langeveld
Department of Clinical Pharmacology, University Hospital Groningen, Groningen, The Netherlands
J Vasc Res 41:377-86. 2004..Consequently, a model for ISR in the rat would be convenient for pathobiological studies. Here we present the full characteristics of a rat ISR model suitable for high throughput stent research...
- Contrast-enhanced 3D MRA with centric ordering in k space: a preliminary clinical experience in imaging the abdominal aorta and renal and peripheral arterial vasculatureA N Shetty
Department of Diagnostic Radiology, William Beaumont Hospital, Royal Oak, MI 48073, USA
J Magn Reson Imaging 8:603-15. 1998..centric reordered, three-dimensional (3D) MR angiography (MRA) pulse sequence in imaging the abdominal aorta and renal and peripheral lower extremity arteries...
- Endovascular repair of paraanastomotic aneurysms after previous open aortic prosthetic reconstructionJoost A van Herwaarden
Department of Vascular Surgery, St Antonius Hospital Nieuwegein, Nieuwegein, The Netherlands
Ann Vasc Surg 18:280-6. 2004..Endovascular repair with bifurcated stent grafts, however, seems to be effective at midterm follow-up...
- Surgical experiences in acute spontaneous dissection of the infrarenal abdominal aortaYusuf Kalko
Cardiovascular Surgery Service, Bezm I Alem Vakif Gureba Hospital, Istanbul, Turkey
Anadolu Kardiyol Derg 8:286-90. 2008Spontaneous dissection of the abdominal aorta should be considered as a vascular surgical emergency. We report here our experience with this rare pathology.
- Prediction of rupture risk in abdominal aortic aneurysm during observation: wall stress versus diameterMark F Fillinger
Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH 03750, USA
J Vasc Surg 37:724-32. 2003..The purpose of this study was to analyze rupture risk over time in patients under observation...
- Elastin degradation and calcification in an abdominal aorta injury model: role of matrix metalloproteinasesDina M Basalyga
Department of Bioengineering, Clemson University, Clemson, SC 29634, USA
Circulation 110:3480-7. 2004..We hypothesized that matrix metalloproteinase (MMP)-mediated vascular remodeling plays a significant role in elastin calcification...
- In vivo deformation of the human abdominal aorta and common iliac arteries with hip and knee flexion: implications for the design of stent-graftsGilwoo Choi
Department of Mechanical Engineering, Stanford University, Stanford, California 94305 5431, USA
J Endovasc Ther 16:531-8. 2009To quantify in vivo deformations of the abdominal aorta and common iliac arteries (CIAs) caused by musculoskeletal motion.
- Staged endovascular stent grafts for concurrent mobile/ulcerated thrombi of thoracic and abdominal aorta causing recurrent spontaneous distal embolizationWayne W Zhang
Division of Vascular Surgery, Department of Surgery, Loma Linda University School of Medicine, 11175 Campus Street, Loma Linda, CA 92350, USA
J Vasc Surg 47:193-6. 2008..Recurrent spontaneous distal embolization may also occur from an ulcerated thrombus of the abdominal aorta. The simultaneous presence of a mobile thrombus in the thoracic aorta and ulcerated thrombus of the abdominal ..
- The value of true-FISP sequence added to conventional gadolinium-enhanced MRA of abdominal aorta and its major branchesAndrea Iozzelli
University of Milan School of Medicine, Department of Medical and Surgical Sciences, Radiology Unit, IRCCS Policlinico San Donato, Via Morandi 30, 20097 San Donato Milanese, Milan, Italy
Eur J Radiol 72:489-93. 2009..with steady-state precession (true-FISP) added to gadolinium-based MR angiography (Gd-MRA) for imaging abdominal aorta and major abdominal vessels, 35 consecutive patients (age 67+/-11 years) with known or suspected abdominal ..
- Placental circulation, fetal growth, and stiffness of the abdominal aorta in newborn infantsMori Akira
Department of Obstetrics and Gynecology, Tokai University School of Medicine, Boseidai, Isehara City, Kanagawa, Japan
J Pediatr 148:49-53. 2006To measure the elastic properties of the abdominal aorta in normal infants and infants who had umbilical placental insufficiency (UPI) before birth.
- Translocation of bacterial NOD2 agonist and its link with inflammationOh Yoen Kim
Cytokines and Inflammation Unit, Institut Pasteur, 28 rue Dr, Roux, 75015 Paris, France
Crit Care 13:R124. 2009..The process could be more frequently identified if peptidoglycan, derived from both Gram-negative and Gram-positive bacteria, was measured...
- Preclinical changes in the mechanical properties of abdominal aorta in obese childrenArcangelo Iannuzzi
Divisione di Medicina Interna, Ospedale S Maria dell Olmo e Costa d Amalfi, Cava de Tirreni, Italy
Metabolism 53:1243-6. 2004..The aim of the present study was to investigate whether preclinical functional changes are detectable in the abdominal aorta of obese children. One hundred consecutively seen obese children and 50 healthy controls were studied...
- Fluid-structure interaction in abdominal aortic aneurysms: effects of asymmetry and wall thicknessChristine M Scotti
Biomedical Engineering Department, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA
Biomed Eng Online 4:64. 2005..which is of significant concern because of the morbidity associated with the continuing expansion of the abdominal aorta and its ultimate rupture...
- Regional distribution of wall thickness and failure properties of human abdominal aortic aneurysmMadhavan L Raghavan
Biomedical Engineering, University of Iowa, 1422 Seamans Center, Iowa City, IA 52242, USA
J Biomech 39:3010-6. 2006..23 mm with only slightly higher readings within a 1cm radius. The failure tension of the specimen strip close to the rupture site was low (11.1 N/cm) compared to its neighborhood in the ruptured aneurysm...
- Aortic aneurysm diameter and risk of cardiovascular mortalityA R Brady
MRC Clinical Trials Unit, London, UK
Arterioscler Thromb Vasc Biol 21:1203-7. 2001..The significant association between aortic diameter and cardiovascular mortality, excluding aneurysm-related deaths, suggests that aneurysm diameter is an independent marker of cardiovascular disease risk...
- Acute abdominal aortic thrombosis in cancer patientsS Poiree
Department of Radiology, Hopital Saint Antoine, 184 rue du Faubourg Saint Antoine, 75012 Paris, France
Abdom Imaging 29:511-3. 2004..Recognition of aortic thrombosis is important because it is a dangerous condition; furthermore, it exposes at the patient to complications such as peripheral embolism. In addition, anticoagulation can result in resolution of thrombosis...
- Severe hypoplasia of the abdominal aorta and its branches in a patient and his daughterA Dejardin
Department of Nephrology, Cliniques Universitaires St Luc UCL, Brussels, Belgium
J Intern Med 255:130-6. 2004We report the history of a patient and his daughter, both affected with hypoplasia of the abdominal aorta and its branches, leading to early and dramatic complications...
- Simple geometric characteristics fail to reliably predict abdominal aortic aneurysm wall stressesJ Hua
UCLA Emergency Medicine Center, UCLA School of Medicine, Los Angeles, Calif 90024, USA
J Vasc Surg 34:308-15. 2001..Future attempts to estimate wall stress and assess risk of rupture for individual AAAs may require detailed three-dimensional modeling...
- The abdominal aorta and constrictive pericarditis: abdominal aortic respiratory variation as an echocardiographic finding in constrictive pericarditisCindy W Tom
Mayo Graduate School of Medicine and Division of Cardiovascular Diseases, 200 First St SW, Rochester, MN 55905, USA
J Am Soc Echocardiogr 18:282-4. 2005
- Mesoscopic simulations of systolic flow in the human abdominal aortaA M Artoli
Section Computational Science, Laboratory for Computing, Systems Architecture and Programming, Faculty of Science, University of Amsterdam, Kruislaan 403, 1098 SJ Amsterdam, The Netherlands
J Biomech 39:873-84. 2006..Simulation results of steady and unsteady flow in a model of the human aortic bifurcation reconstructed from magnetic resonance angiography, are presented as a typical hemodynamic application...
- Durability of open repair of infrarenal abdominal aortic aneurysm: a 15-year follow-up studyFausto Biancari
Department of Cardiothoracic and Vascular Surgery, Oulu University Hospital, 90221 Oulu, Finland
J Vasc Surg 35:87-93. 2002..This study reviewed the long-term outcome of patients who underwent open repair of infrarenal abdominal aortic aneurysms (AAAs)...
- Comparison between measures of atherosclerosis and risk of stroke: the Rotterdam StudyM Hollander
Department of Epidemiology and Biostatistics, Erasmus Medical Center Rotterdam, PO Box 1738, 3000 DR Rotterdam, Netherlands
Stroke 34:2367-72. 2003..We compared different measures of atherosclerosis in relation to stroke...
- The epidemiology of abdominal aortic diameterMatthew A Allison
Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA 92093 0811, USA
J Vasc Surg 48:121-7. 2008The diameter of the abdominal aorta is central to the diagnosis of abdominal aortic aneurysm...
- Correlation of abdominal fat accumulation and stiffness of the abdominal aorta in obese childrenTugcin Bora Polat
Department of Pediatric Cardiology, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Hospital, Turkey
J Pediatr Endocrinol Metab 21:1031-40. 2008To evaluate abdominal adipose tissue accumulation in obese children by ultrasound measurement and compare with the elastic properties of the abdominal aorta.
- Anteroposterior diameter of the infrarenal abdominal aorta is higher in women with polycystic ovary syndromeMarco Matteo Ciccone
Institute of Cardiovascular Diseases, Azienda Ospedaliera Policlinico, Piazza Giulio Cesare 11, 70124 I, Italy
Vasc Health Risk Manag 5:561-6. 2009..Women affected by polycystic ovary syndrome (PCOS) are known to be at higher risk of cardiovascular disease. The aim of this study was to identify the artery that first is affected by early pre-atherosclerotic changes in PCOS...
- Fluid-structure interaction effects on sac-blood pressure and wall stress in a stented aneurysmZ Li
Department of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC 27695 7910, USA
J Biomech Eng 127:662-71. 2005..All simulation results are in agreement with experimental data and clinical observations...
- Cross talk between kinin and angiotensin II receptors in mouse abdominal aortaEliete S Rodrigues
Department of Biophysics, Universidade Federal de Sao Paulo Escola Paulista de Medicina, Sao Paulo, Brazil
Biol Chem 390:907-13. 2009..We conclude that cross talk between kinin and AngII receptors occurs in mouse abdominal aorta and that both peptides may regulate the initiation and progression of important pathophysiological processes, ..
- Positron emission tomography (PET): evaluation of chronic periaortitisCarlo Salvarani
Arcispedale S Maria Nuova, Reggio Emilia, Italy
Arthritis Rheum 53:298-303. 2005..To evaluate the presence and extent of large-vessel inflammation in patients with chronic periaortitis (CP) using (18)F-fluorodeoxyglucose-positron emission tomography (FDG-PET)...
- Development of velocity profiles and retrograde flow in the porcine abdominal aorta under different haemodynamic conditionsE M Pedersen
Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Skejby Sygehus, Denmark
Scand Cardiovasc J 33:206-14. 1999..was to provide in vivo data on the development of velocity profiles and oscillating blood velocities in the abdominal aorta under varying haemodynamic conditions. Six anaesthetized, 90-kg pigs were used in the study...
- MRA of the abdominal aorta and lower extremitiesT M Grist
Department of Radiology, University of Wisconsin Madison, 53792 3252, USA
J Magn Reson Imaging 11:32-43. 2000..The objective of this manuscript is to review the current state-of-the-art of MRA of the abdominal aorta and lower extremity vessels...
- Effect of lipid-lowering therapy with atorvastatin on atherosclerotic aortic plaques detected by noninvasive magnetic resonance imagingAtsushi Yonemura
National Defense Medical College, Saitama, Japan
J Am Coll Cardiol 45:733-42. 2005..We sought to elucidate the effects of 20-mg versus 5-mg atorvastatin on thoracic and abdominal aortic plaques...
- Effects of intestinal ischemia-reperfusion on major conduit arteriesC Koksoy
Department of Surgery, Ankara University Medical School, Turkey
J Invest Surg 13:35-43. 2000..The following mechanisms of vasomotor functions were studied in abdominal aorta, superior mesenteric, renal, pulmonary, and carotid arterial rings: (1) endothelial-dependent vasodilation ..
- Injury to the abdominal aorta during laparoscopic surgery: an unusual presentationA Mases
Department of Anesthesiology, Hospital Universitario del Mar, Universitat Autonoma de Barcelona, Spain
Anesth Analg 91:561-2. 2000Laparoscopic cholecystectomy is a very common surgical procedure, and vascular injuries account for one third of major complications during this surgery. We describe an unusual presentation of an abdominal aorta injury.
- p-ANCA-associated periaortitis with histological proof of Wegener's granulomatosis: case reportT Carels
Department of Internal Medicine, University Hospital Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium
Clin Rheumatol 24:83-6. 2005..This case report illustrates an unusual disease course in WG, resembling large vessel vasculitis, and we discuss the possible mechanisms of large vessel involvement in this form of vasculitis...
- Hand-assisted laparoscopic aortobifemoral bypass for occlusive disease. Early and mid-term resultsI Fourneau
Department of Vascular Surgery, University Hospital Gasthuisberg, Leuven, Brabant, Belgium
Eur J Vasc Endovasc Surg 30:489-93. 2005..To evaluate the early and mid-term results of hand-assisted laparoscopic surgery (HALS) for aorto-iliac reconstruction...
- Abdominal aortic calcific deposits are an important predictor of vascular morbidity and mortalityP W Wilson
From the NHLBI's Framingham Heart Study and Boston University School of Medicine, Framingham, Massachusetts, USA
Circulation 103:1529-34. 2001..CONCLUSIONS: AAC deposits, detected by lateral lumbar radiograms, are a marker of subclinical atherosclerotic disease and an independent predictor of subsequent vascular morbidity and mortality...
- Hemodynamics simulation and identification of susceptible sites of atherosclerotic lesion formation in a model abdominal aortaJ R Buchanan
Department of Mechanical and Aerospace Engineering, North Carolina State University, Campus Box 7910, 3211 Broughton Hall, Raleigh, NC 27695 7910, USA
J Biomech 36:1185-96. 2003Employing the rabbit's abdominal aorta as a suitable atherosclerotic model, transient three-dimensional blood flow simulations and monocyte deposition patterns were used to evaluate the following hypotheses: (i) simulation of monocyte ..
- Stiffness of the abdominal aorta in obese childrenErturk Levent
Department of Pediatric Cardiology, Faculty of Medicine, Ege University, Bornova, Izmir, Turkey
J Pediatr Endocrinol Metab 15:405-9. 2002..The purpose of this study was to assess the stiffness of the abdominal aorta using transthoracic echocardiography in normotensive obese and hypertensive obese pediatric patients and a ..
- In vivo quantification of blood flow and wall shear stress in the human abdominal aorta during lower limb exerciseCharles A Taylor
Department of Surgery, Stanford University, CA, USA
Ann Biomed Eng 30:402-8. 2002..exercise bicycle were used to measure, in vivo, the effects of exercise on hemodynamic conditions in the abdominal aorta of eleven young, healthy subjects. Heart rate increased from 73 +/- 6.2 beats/min at rest to 110 +/- 8...
- Surgical treatment for primary infected aneurysm of the descending thoracic aorta, abdominal aorta, and iliac arteriesRon Bin Hsu
Department of Surgery and Institute of Clinical Medicine, National Taiwan University Hospital, and Far Eastern Memorial Hospital, Taiwan, ROC
J Vasc Surg 36:746-50. 2002..In this retrospective review, we report the surgical results of infected aortic aneurysms treated at a single center over 5 years...
- Abdominal aortic calcific deposits are associated with increased risk for congestive heart failure: the Framingham Heart StudyCraig R Walsh
Framingham Heart Study, Framingham, Mass 01702, USA
Am Heart J 144:733-9. 2002We sought to determine the association of aortic atherosclerosis, detected by calcific deposits in the abdominal aorta seen on lateral lumbar radiographs, with risk for congestive heart failure (CHF).
- Assessment of the abdominal aorta and its visceral branches by contrast-enhanced dynamic volumetric hepatic parallel magnetic resonance imaging: feasibility, reliability and accuracyRobert Werder
Institute of Diagnostic Radiology, University Hospital Zurich, Zurich, Switzerland
Eur Radiol 17:541-51. 2007..to shorten breath-hold times (parallel GRE MRI) in the detection of arterial variants and stenosis of the abdominal aorta and its visceral branches...
- Detection of abdominal aortic calcification with lateral spine imaging using DXAJohn T Schousboe
Park Nicollet Health Services, Minneapolis, MN 55416, USA
J Clin Densitom 9:302-8. 2006..Lateral imaging of the spine with DXA intended to detect vertebral fracture is a promising technology for the simultaneous assessment of a risk factor for cardiovascular disease incidence and death...
- Use of dynamic computed tomography to evaluate pre- and postoperative aortic changes in AAA patients undergoing endovascular aneurysm repairArno Teutelink
Departments of Vascular Surgery, University Medical Center, Utrecht, The Netherlands
J Endovasc Ther 14:44-9. 2007..To utilize dynamic computed tomographic angiography (CTA) on pre- and postoperative endovascular aneurysm repair (EVAR) patients to characterize cardiac-induced aortic motion within the aneurysm neck, an essential EVAR sealing zone...
- Jagged1 gene mutation for abdominal coarctation of the aorta in Alagille syndromeAnnick Raas-Rothschild
Department of Human Genetics, Hadassah Hebrew University Hospital, Jerusalem, Israel
Am J Med Genet 112:75-8. 2002..Mutation analysis of the Jagged1 gene in this fourth reported patient with coarctation of the abdominal aorta in AGS and right subclavian stenosis identified a mutation deletion (1485 Del CT)...
- Imaging of Aortic Atherosclerosis and Inflammation in the Metabolic SyndromeWarren J Manning; Fiscal Year: 2012..Atherosclerosis primarily affects large and medium sized vessels with autopsy data demonstrating that the abdominal aorta offers a valuable early window for the study of atherosclerosis...
- Angiotensin II uncoupling of eNOS in hypertensionHUA LINDA CAI; Fiscal Year: 2013..Ultrasound monitoring of abdominal aorta diameter in the survived mice and immediate dissection of the suddenly died mice revealed expansive or ..
- Abdominal Adipose Tissue InflammationPeter S Tobias; Fiscal Year: 2013..examine a distinct atherosclerosis pathology to understand the cause of the exacerbated lesions found in the abdominal aorta of hyperlipidemic mice challenged with a chronic, systemic proinflammatory stimulus...
- CCN3 and aortic aneurysmZhiyong Lin; Fiscal Year: 2013..These lesions in both the thoracic and abdominal aorta can deteriorate resulting in dissection and /or rupture...
- Mechanisms of abdominal aortic aneurysm formationAlan Daugherty; Fiscal Year: 2010..II promotes aneurysm formation by initiating regional-specific matrix degradation in the media of the abdominal aorta, leading to recruitment of macrophages, medial dissection, and subsequent vascular remodeling...
- The Role of LOX/LOXL Family Members in Abdominal Aortic Aneurysms (AAA)EBONY WASHINGTON; Fiscal Year: 2010..AAA is a permanent dilation of the abdominal aorta that exceeds the normal aortic diameter by more than 50%...
- Identifying Epidemiological Risk Factors for Abdominal Aortic AneurysmWeihong Tang; Fiscal Year: 2013..exams in the Atherosclerosis Risk in Communities (ARIC) Study to perform an ultrasound examination of the abdominal aorta to identify undiagnosed AAA cases in this large population-based cohort...
- Role of IgE in AtherosclerosisGuo Ping Shi; Fiscal Year: 2013..apolipoprotein E-deficient (Apoe-/-) mice developed 75% fewer lipid depositions in the thoracic-abdominal aorta and had a >50% reduction in atherosclerotic lesion sizes in the aortic arch, compared with Apoe-/- control ..
- Intrinsic Vascular Smooth Muscle Cell StiffnessStephen F Vatner; Fiscal Year: 2013..increases with aging and this aging alteration is greater in males than females, and also much greater in the abdominal aorta (AA) vs. the thoracic aorta (TA), which is only partially explained by variance in extracellular matrix (ECM)...
- Mechanisms of uremic vascular calcificationKoba A Lomashvili; Fiscal Year: 2013..injecting calcitriol in wild type uremic chimeric mice with vitamid D receptor deficient (VDR-/-) portions of abdominal aorta (chimera created by surgical transplantation)...
- Endovascular device and treatment for stabilizing aortic aneurysmsMATTHEW FRANK OGLE; Fiscal Year: 2010..For these studies, the device will be deployed to isolate a region of porcine infrarenal abdominal aorta, allowing PGG to be delivered to this specific region...
- Promoting Walking in African Americans with Peripheral Arterial DiseaseTRACIE CHIANTI COLLINS; Fiscal Year: 2013..disease (PAD) - a disease which affects 12 million Americans and is defined as atherosclerosis of the abdominal aorta and arteries of the lower extremities. Compared to non-Hispanic whites, AAs are 2.3 to 2...
- Mechanisms and Significance of Angiogenesis in AAA DiseaseRonald L Dalman; Fiscal Year: 2013Project Summary/Abstract Abdominal aorta aneurysm (AAA) is a common and lethal disease of adult Americans...
- Biologically inspired engineering of hierarchical vascular networksGeorge Eng; Fiscal Year: 2013..of the cardiac graft will be assessed in vivo an interposition graft in an end to end anastomosis in the rat abdominal aorta. The specific aims of the proposal will be to (1) Use micro fabrication technologies to create a ..
- Hemodynamics and AAA disease: Uncovering the Hidden ConnectionsShawn C Shadden; Fiscal Year: 2012..Evi- dence suggests that the nature of blood flow in the abdominal aorta is largely responsible for AAA initiation and progression...
- Development of a Biological Stent Graft for Aorta Aneurysm RepairNICOLAS L apos HEUREUX; Fiscal Year: 2010DESCRIPTION (provided by applicant): Abdominal aorta aneurysms (AAA) are diagnosed in more than 100,000 patients in the U.S. each year. About 70% of these patients require surgical intervention to prevent aneurysm progression...
- Critical Role of Inflammatory Macrophages in AAA PathogenesisRonald L Dalman; Fiscal Year: 2012DESCRIPTION (provided by applicant): Abdominal aorta aneurysm (AAA) is a common and lethal disease of adult Americans...
- INHIBITORY LEFT ATRIAL INFLUENCES ON THE BAROREFLEXDavid Ramsay; Fiscal Year: 1991..of cuffs placed around the thoracic portion of the inferior vena cava, pulmonary artery, ascending aorta and abdominal aorta proximal to the renal arteries...
- Bioengineering Studies of Abdominal Aortic Aneurysm Fluid and Wall DynamicsENDER FINOL; Fiscal Year: 2009..environment of the native AAAs will be reproduced by non-invasively evaluating blood flow in the abdominal aorta, aneurysmal wall thickness and wall motion as it is mediated by the cardiac cycle...
- Biologic Ventricular Assist DeviceRobert Kloner; Fiscal Year: 2004..cells approximately 3 mm in length and about 2 mm in thickness will be made upon the outer wall of the abdominal aorta above the take off of the renal arteries of the rat...
- HEMODYNAMICS AND LDL PERMEABILITY IN THE ARTERIAL WALLGEORGE TRUSKEY; Fiscal Year: 1992..The proposed research will examine: a) the rates of entry of LDL into the rabbit abdominal aorta at sites prone to the development of atherosclerotic lesions; b) the dependence of permeability upon the ..
- B VITAMIN ATHEROSCLEROSIS INTERVENTION TRAILHOWARD HODIS; Fiscal Year: 2004..B-mode ultrasonograms of carotid artery intima-media thickness and EBCT of the coronary arteries and abdominal aorta. B-vitamin supplementation may provide a promising approach for reducing the progression of atherosclerosis ..
- GENETIC BASIS OF ABDOMINAL AORTIC ANEURYSMRobert Ferrell; Fiscal Year: 2000DESCRIPTION: (Adapted from Investigator's Abstract) Abdominal aortic aneurysm (AAA) is a dilatation of the abdominal aorta which can, if undetected, lead to rupture...
- Site Directed Thrombolytic AgentELEANOR MCGOWAN; Fiscal Year: 2003..is to assess the pre-clinical efficacy of a direct thrombolytic agent delivered locally in a rabbit model of abdominal aorta thrombosis...
- Matrix Metalloproteinases in Thoracic Aortic DissectionSCOTT LEMAIRE; Fiscal Year: 2009..Accumulating data demonstrates that MMPs are involved in the pathogenesis of aneurysms of the abdominal aorta, intracranial vessels, and coronary arteries...
- FETAL UPTAKE AND DISTRIBUTION OF LOCAL ANESTHETICSROLAND KENNEDY; Fiscal Year: 1980..arterial concentration difference is evaluated by blood samples from the umbilical vein (UV) and fetal abdominal aorta (FA)...
- Aortic Wall Microarchitecture and Cyclic StrainChristopher Zarins; Fiscal Year: 2007..are thought to play an important role, particularly in the differing susceptibility of the thoracic and abdominal aorta to these degenerative changes...
- VON WILLEBRAND'S DISEASE AND ATHEROSCLEROSISValentin Fuster; Fiscal Year: 1990..in localizing platelet vessel wall interaction and atherogenesis which is most prominent in the lower abdominal aorta and at the iliac artery...
- HDL AND PLAQUES--NOVEL MODELS AND IMAGING TECHNIQUESEdward Fisher; Fiscal Year: 2001..In aim 3, magnetic resonance imaging (MRI), capable of noninvasively characterizing advanced lesions in mouse abdominal aorta, will be further developed to serially assess lesion changes in mice (from Projects 1 and 2) during plaque ..
- DRUG TREATMENT OF VASCULAR SCLEROPROTEIN DEFECTSROBERT BOUCEK; Fiscal Year: 1980..available test mode system (spontaneous fragmentation of elastic membranes and aneurysms of the abdominal aorta), we find a relationship between the adrenergic input, the chemistry of elastin lysyl-derived cross-links and ..
- Cardiac MR of Subclin CVD: Impact of AgeWARREN MANNING; Fiscal Year: 2005..We propose to expand our Pilot study to perform heart and thoracic/abdominal aorta MRI studies in 2400 FHS participants to allow for identification of individual CVD risk factors for ..
- MECHANISM OF COCAINE INDUCED ATHEROGENESISRenu Virmani; Fiscal Year: 1993..in a preliminary study on "Pathobiologic determinants of atherosclerosis in youth" that the thoracic and abdominal aorta from young cocaine associated death victims (19 patients) had increased sudanophilia in the absence of well ..
- Novel Anti-Inflammatory To Treat AtherosclerosisPAUL BORRON; Fiscal Year: 2005..and their respective subclasses in serum of apoE-KO mice treated with COG133 C) volume of plaque in thoraco-abdominal aorta The outcome of these Phase 1 studies will permit a preliminary evaluation of the feasibility of employing ..
- Device Design for Treatment of Aortic DiseaseDavid Saloner; Fiscal Year: 2005..for the rapid description and evaluation of hemodynamic forces on devices used for treating aneurysms of the abdominal aorta. Validation of the simulation software will be provided by innovative imaging techniques...
- DEVELOPMENT OF A BIOARTIFICIAL ARTERYRobert Tranquillo; Fiscal Year: 2002..knowledge, will be exploited in this research to obtain the target mechanical properties (those of the rat abdominal aorta)...
- MINORITY SCHOOL FACULTY DEVELOPMENT AWARDJOEL TRUPIN; Fiscal Year: 1993..The source of normal and atherosclerotic SMC for this study will be the abdominal aorta of the hyperlipidemic pig...
- HEART PRESERVATION AND TRANSPLANTATION STUDIESCARLOS LEMMI; Fiscal Year: 1980..afferent and efferent arcs of the immune response to tissue and organ transplantation with the heterotropic (abdominal aorta) heart transplant in the rat as the major model...
- Development of Collagen-Based Engineered Blood VesselsJoel Stitzel; Fiscal Year: 2009..The scaffold will be developed and cultured with vascular cells in a bioreactor capable of controlled pulsatile flow. The scaffold will be evaluated in an in vivo rabbit abdominal aorta replacement model.
- MATRIX GLA PROTEIN AND CARTILAGE CALCIFICATIONPaul Price; Fiscal Year: 2001..The investigators will further study the demonstrated ability of MGP to inhibit calcification in supersaturated solutions, and will investigate the ability of MGP to inhibit matrix vesicle -initiated calcification. ..
- AVIAN VASCULAR FUNCTIONHiroko Nishimura; Fiscal Year: 2007..relationship among incremental increases in BP, hemodynamic forces selective to the lower segment of the abdominal aorta and endothelial dysfunction, leading to the formation of neointimal plaques (NPs)...
- Initiation and Inhibition of Medial Artery CalcificationPaul Price; Fiscal Year: 2008..abstract_text> ..
- VOLUMETRIC ANALYSIS OF THE AORTA AND ITS BRANCHESGeoffrey Rubin; Fiscal Year: 2002....
- Improving Radiologist Detection of Lung Nodules with CADGeoffrey Rubin; Fiscal Year: 2008..abstract_text> ..
- Abdominal Aortic AneurysmM Tilson; Fiscal Year: 2005..Recent approaches such as the search for candidate genes and the methodology of genome wide scanning among AAA families or sibling pairs will be discussed. ..
- Homocysteine/Hypertension & Vascular Lesion FormationPeter Lin; Fiscal Year: 2008..abstract_text> ..
- Optimizing Cardiovascular Devices Thrombogenicity for Eliminating AnticoagulationDanny Bluestein; Fiscal Year: 2009..It is envisioned that it will also facilitate the use of these devices for long term therapy by reducing the need for difficult pharmacological management with anticoagulants, which is mandated for most existing devices. ..
- HOMOCYSTEINE, INFLAMMATION, AND ATHEROGENESISMichael Rosenfeld; Fiscal Year: 2001..Under Aim 2, the investigator will determine the mechanism by which HC and lipid accumulation alter glutathione and NADH/NADPH metabolism, thereby activating macrophages in vitro. ..
- THE ROLE OF WALL STRESS DISTRIBUTION IN ABDOMINAL AORTICMark Fillinger; Fiscal Year: 2001..The results from this study will provide critical insight into the role of wall stresses during AAA disease progression and rupture, and may give clinicians a noninvasive tool to more ..
- Transplantation Immunology ConferenceAngus Thomson; Fiscal Year: 2002..An important goal will be evaluation of future research directions, as well as critical appraisal of contemporary "cutting edge" research. ..
- Role of Nesprin in Flow-Mediated Endothelial MechanotransductionAbdul Barakat; Fiscal Year: 2008..The proposed research aims to understand how a fluid mechanical force is transmitted from the cell surface to the nucleus where the genetic changes occur. [unreadable] [unreadable] [unreadable]..
- Imaging and Laser Revascularization in HibernationLynne Johnson; Fiscal Year: 2003....
- Estrogen Receptor Variants,HDL, and AtherosclerosisDavid Herrington; Fiscal Year: 2005..T/C variant (and several other ER-alpha polymorphisms) and extent of atherosclerosis in the thoracic and abdominal aorta and the right coronary artery in female subjects in the PDAY study (N=700)...
- Thrombosis Gene Polymorphisms and Early CHD Risk in HERSDavid Herrington; Fiscal Year: 2004....
- Non-traditional Cardiovascular Risk Factors in DM type 2Peter Reaven; Fiscal Year: 2004..Long- term (future) aims will include evaluating the prospective relationship of these novel cardiovascular risk factors to the progression of atherosclerosis and the development of macrovascular disease in this same population. ..
- Novel Organ Culture & Theory for Arteriolar RemodelingJAY HUMPHREY; Fiscal Year: 2005..We will collect simultaneous pressure-diameter, cell morphological, and actin cytoskeletal data at multiple times during the remodeling, which in turn will allow us to develop a novel, single theoretical framework. ..
- Mechanisms of Renal Na+ Pump Stimulation by AngiotensinDOUGLAS YINGST; Fiscal Year: 2005..These results have important implications for understanding normal kidney function, as well as the development of hypertension and heart failure. ..
- Arterial 5-HT Transporter FunctionStephanie Watts; Fiscal Year: 2009..abstract_text> ..
- 3T Atherosclerotic MRI and Carotid Artery Scoring SystemChun Yuan; Fiscal Year: 2009....
- Mechanical Stretch and Vein Graft Intimal HyperplasiaJeremy Goldman; Fiscal Year: 2005..Specific Aim II: Investigate the role of platelet-derived growth factor (PDGF)-BB and related signaling molecules in mediating subsequent vascular cell proliferation. ..
- Conference Proposal: Transplantation ImmunologyAngus Thomson; Fiscal Year: 2004..An important goal will be evaluation of future research directions, as well as critical appraisal of contemporary "cutting edge" research. ..
- Osteoprotegerin and osteopontin in aortic aneurysmJonathan Golledge; Fiscal Year: 2009..Understanding the role of these calcium-controlling proteins in artery weakness and how drug therapy can interfere in these effects is an important step in the development of new treatment for aortic aneurysm. ..
- Development of Navigator Coronary MRIYi Wang; Fiscal Year: 2010....
- 2007 Atherosclerosis Gordon Research ConferenceMichael Rosenfeld; Fiscal Year: 2007..The [unreadable] conference will provide a comprehensive overview of current research on [unreadable] atherosclerosis with a focus on the latest and most exciting developments in the field. [unreadable] [unreadable] [unreadable]..