perineum

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Top Publications

  1. ncbi Traditional care of the perineum during birth. A prospective, randomized, multicenter study of 1,076 women
    Klaus Mayerhofer
    Departments of Gynecology and Obstetrics and of Medical Computer Sciences, University of Vienna Medical School, and Semmelweis Frauenklinik, A 1090 Vienna, Wahringer Gurtel 18 20, Austria
    J Reprod Med 47:477-82. 2002
  2. pmc Is throat screening necessary to detect methicillin-resistant Staphylococcus aureus colonization in patients upon admission to an intensive care unit?
    Stephan Harbarth
    J Clin Microbiol 45:1072-3. 2007
  3. ncbi Is Asian ethnicity an independent risk factor for severe perineal trauma in childbirth? A systematic review of the literature
    Janet Wheeler
    Liverpool Hospital, Sydney South West Area Health Service, Elizabeth Street, Liverpool, NSW, 2170, Australia
    Women Birth 25:107-13. 2012
  4. ncbi Laparoscopic-assisted versus open abdominoperineal resection for low rectal cancer: a prospective randomized trial
    Simon S M Ng
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    Ann Surg Oncol 15:2418-25. 2008
  5. pmc Cell lineage analysis demonstrates an endodermal origin of the distal urethra and perineum
    Ashley W Seifert
    Department of Zoology, University of Florida, Cancer Genetics Research Complex, PO Box 103610, Gainesville, FL 32610 3610, USA
    Dev Biol 318:143-52. 2008
  6. ncbi Risk factors for 3rd and 4th degree perineal tear
    O Eskandar
    Department of Obstetrics and Gynaecology, North Devon District Hospital, Barnstaple, UK
    J Obstet Gynaecol 29:119-22. 2009
  7. ncbi Trans-rectal versus trans-perineal saturation rebiopsy of the prostate: is there a difference in cancer detection rate?
    Firas Abdollah
    University Vita Salute San Raffaele Hospital, Milan, Italy
    Urology 77:921-5. 2011
  8. ncbi Oncological outcomes after total mesorectal excision for cure for cancer of the lower rectum: anterior vs. abdominoperineal resection
    Arne Wibe
    Department of Surgery, St Olavs Hospital, Trondheim, Norway
    Dis Colon Rectum 47:48-58. 2004
  9. pmc Unusual anogenital apocrine tumor resembling mammary-like gland adenoma in male perineum: a case report
    Kazuhito Hatanaka
    Department of Molecular and Cellular Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8 35 1 Sakuragaoka, Kagoshima 890 8544, Japan
    Diagn Pathol 5:42. 2010
  10. ncbi Perineal techniques during the second stage of labour for reducing perineal trauma
    Vigdis Aasheim
    Department of Postgraduate Studies, Bergen University College, Møllendalsveien 6, PO Box7030, Bergen, Norway, 5020
    Cochrane Database Syst Rev 12:CD006672. 2011

Detail Information

Publications270 found, 100 shown here

  1. ncbi Traditional care of the perineum during birth. A prospective, randomized, multicenter study of 1,076 women
    Klaus Mayerhofer
    Departments of Gynecology and Obstetrics and of Medical Computer Sciences, University of Vienna Medical School, and Semmelweis Frauenklinik, A 1090 Vienna, Wahringer Gurtel 18 20, Austria
    J Reprod Med 47:477-82. 2002
    ..To investigate the influence of the traditional hands-on versus the innovative hands-poised method on the risk of perineal trauma during vaginal delivery and on neonatal outcomes...
  2. pmc Is throat screening necessary to detect methicillin-resistant Staphylococcus aureus colonization in patients upon admission to an intensive care unit?
    Stephan Harbarth
    J Clin Microbiol 45:1072-3. 2007
  3. ncbi Is Asian ethnicity an independent risk factor for severe perineal trauma in childbirth? A systematic review of the literature
    Janet Wheeler
    Liverpool Hospital, Sydney South West Area Health Service, Elizabeth Street, Liverpool, NSW, 2170, Australia
    Women Birth 25:107-13. 2012
    ..To undertake a systematic review of the literature to determine whether Asian ethnicity is an independent risk factor for severe perineal trauma in childbirth...
  4. ncbi Laparoscopic-assisted versus open abdominoperineal resection for low rectal cancer: a prospective randomized trial
    Simon S M Ng
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    Ann Surg Oncol 15:2418-25. 2008
    ..Recurrence and survival data were also recorded and compared between the two groups...
  5. pmc Cell lineage analysis demonstrates an endodermal origin of the distal urethra and perineum
    Ashley W Seifert
    Department of Zoology, University of Florida, Cancer Genetics Research Complex, PO Box 103610, Gainesville, FL 32610 3610, USA
    Dev Biol 318:143-52. 2008
    ..Surprisingly, the lineage map also revealed an endodermal origin of the perineum, which is the first demonstration that endoderm differentiates into skin...
  6. ncbi Risk factors for 3rd and 4th degree perineal tear
    O Eskandar
    Department of Obstetrics and Gynaecology, North Devon District Hospital, Barnstaple, UK
    J Obstet Gynaecol 29:119-22. 2009
    ..On the other hand, induction of labour (IOL), epidural analgesia and instrumental delivery for occipitoanterior position are protective factors against anal sphincter injury, although they did not reach statistical significance...
  7. ncbi Trans-rectal versus trans-perineal saturation rebiopsy of the prostate: is there a difference in cancer detection rate?
    Firas Abdollah
    University Vita Salute San Raffaele Hospital, Milan, Italy
    Urology 77:921-5. 2011
    ..To test the hypothesis that there is no significant difference in the rate of prostate cancer (PCa) detection rate between the transrectal and transperineal approach in men undergoing a saturation (24-core) prostate rebiopsy...
  8. ncbi Oncological outcomes after total mesorectal excision for cure for cancer of the lower rectum: anterior vs. abdominoperineal resection
    Arne Wibe
    Department of Surgery, St Olavs Hospital, Trondheim, Norway
    Dis Colon Rectum 47:48-58. 2004
    ..This study was designed to examine the outcome of cancer of the lower rectum, particularly the rates of local recurrence and survival for tumors located in this area that have been treated by anterior or abdominoperineal resections...
  9. pmc Unusual anogenital apocrine tumor resembling mammary-like gland adenoma in male perineum: a case report
    Kazuhito Hatanaka
    Department of Molecular and Cellular Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8 35 1 Sakuragaoka, Kagoshima 890 8544, Japan
    Diagn Pathol 5:42. 2010
    ..no mammary-like glands were present in the dermis around the tumor, this unusual apocrine tumor has been suggested to be derived from male anogenital mammary-like glands and mimic a mammary-like gland adenoma in the male perineum.
  10. ncbi Perineal techniques during the second stage of labour for reducing perineal trauma
    Vigdis Aasheim
    Department of Postgraduate Studies, Bergen University College, Møllendalsveien 6, PO Box7030, Bergen, Norway, 5020
    Cochrane Database Syst Rev 12:CD006672. 2011
    ..Different perineal techniques and interventions are being used to prevent perineal trauma. These interventions include perineal massage, warm compresses and perineal management techniques...
  11. pmc How good are we at implementing evidence to support the management of birth related perineal trauma? A UK wide survey of midwifery practice
    Debra E Bick
    Professor of Evidence Based Midwifery Practice Kings College London, Florence Nightingale School of Nursing and Midwifery, 57 Waterloo Road, London SE1 8WA, UK
    BMC Pregnancy Childbirth 12:57. 2012
    ..We wished to identify how midwives in the UK assessed and repaired perineal trauma and the extent to which practice reflected evidence based guidance. Findings would be used to inform the content of a large intervention study...
  12. ncbi Perineal outcomes and maternal comfort related to the application of perineal warm packs in the second stage of labor: a randomized controlled trial
    Hannah G Dahlen
    Sydney South Western Area Health Service, Sydney, New South Wales, Australia
    Birth 34:282-90. 2007
    ..The aim of this study was to determine the effects of applying warm packs to the perineum on perineal trauma and maternal comfort during the late second stage of labor.
  13. pmc Characteristics associated with severe perineal and cervical lacerations during vaginal delivery
    Helain J Landy
    of Obstetrics and Gynecology, Georgetown University Hospital, MedStar Health, Washington, DC 20007 2110, USA
    Obstet Gynecol 117:627-35. 2011
    ..To characterize potentially modifiable risk factors for third- or fourth-degree perineal lacerations and cervical lacerations in a contemporary U.S. obstetric practice...
  14. ncbi The development of the male genitourinary system. I. The origin of the urorectal septum and the formation of the perineum
    P J Hynes
    Department of Anatomy, University College, Cork, Ireland
    Br J Plast Surg 57:27-36. 2004
    ..1) division of the cloaca into the urogenital sinus and hindgut by the urorectal septum and the formation of the perineum; (2) the extension of the cloaca and its epithelium in the form of the urethral plate through the developing ..
  15. pmc No reduction in instrumental vaginal births and no increased risk for adverse perineal outcome in nulliparous women giving birth on a birth seat: results of a Swedish randomized controlled trial
    Li Thies-Lagergren
    Department of Women s and Children s Health, Division of Reproductive and Perinatal Health Care, Karolinska Institutet, Stockholm SE 171 76, Sweden
    BMC Pregnancy Childbirth 11:22. 2011
    ....
  16. ncbi Risk factors and obstetric complications associated with macrosomia
    N E Stotland
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, CA, USA
    Int J Gynaecol Obstet 87:220-6. 2004
    ..Macrosomia is associated with adverse maternal outcomes. The objective of this study was to characterize the epidemiology of macrosomia and related maternal complications...
  17. ncbi Risk factors for third degree perineal ruptures during delivery
    J W De Leeuw
    Department of Obstetrics and Gynaecology, Ikazia Hospital, The Netherlands
    BJOG 108:383-7. 2001
    ..If the obstetric situation permits use of either instrument, the vacuum extractor should be the instrument of choice with respect to the prevention of faecal incontinence...
  18. ncbi Fecal and urinary incontinence in primiparous women
    Diane Borello-France
    Duquesne University, Department of Physical Therapy, Pittsburgh, Pennsylvania 15282, USA
    Obstet Gynecol 108:863-72. 2006
    ..To prospectively investigate the relationship between anal sphincter tears and postpartum fecal and urinary incontinence...
  19. ncbi An Australian prospective cohort study of risk factors for severe perineal trauma during childbirth
    Hannah G Dahlen
    Sydney South Western Area Health Service, RPA Women and Babies, Missenden Road, Camperdown 2050, NSW, Australia
    Midwifery 23:196-203. 2007
    ..to determine risk factors for the occurrence of severe perineal trauma (third and fourth degree tears) during childbirth...
  20. ncbi Radical perineal prostatectomy: cost efficient, outcome effective, minimally invasive prostate cancer management
    Michael J Harris
    Northern Institute of Urology, 1020 Sixth Street, Traverse City, MI 49684, USA
    Eur Urol 44:303-8; discussion 308. 2003
    ..This method of anatomic radical perineal prostatectomy has been developed to accomplish a minimally invasive method of achieving goals of disease control and preservation of genito-urinary functions...
  21. ncbi Systematic transperineal ultrasound-guided template biopsy of the prostate: three-year experience
    David M Pinkstaff
    Department of Urology, Mayo Clinic, Jacksonville, Florida 32224, USA
    Urology 65:735-9. 2005
    ..To review the technique of transperineal saturation prostate biopsy and to update our results on patients at high risk of prostate cancer...
  22. ncbi Women's experiences after a third-degree obstetric anal sphincter tear: a qualitative study
    Abimbola Williams
    Urodynamics Department, Liverpool Women s Hospital, Liverpool, United Kingdom
    Birth 32:129-36. 2005
    ..The objective of this study was to explore the views and experiences of women in the postpartum period after sustaining a third-degree obstetric anal sphincter tear...
  23. ncbi Tears in the vagina, perineum, sphincter ani, and rectum and first sexual intercourse after childbirth: a nationwide follow-up
    Ingela Rådestad
    Department of Caring Sciences and Public Health, Mälardalen s University, Eskilstuna, Sweden
    Birth 35:98-106. 2008
    ..The purpose of this study was to investigate whether or not tears in the vagina, perineum, sphincter ani, or rectum hindered sexual intercourse during the year after childbirth.
  24. ncbi The devlopment of the perineum in the human. A comprehensive histological study with a special reference to the role of the stromal components
    S C J van der Putte
    Department of Pathology, University Medical Centre Utrecht, The Netherlands
    Adv Anat Embryol Cell Biol 177:1-131. 2005
  25. ncbi Evaluation of postpartum perineal pain and dyspareunia--a prospective study
    Vasanth Andrews
    Clinical Research Fellow, Mayday University Hospital, United Kingdom
    Eur J Obstet Gynecol Reprod Biol 137:152-6. 2008
    ..We aimed to determine the prevalence of dyspareunia and perineal pain using validated pain scores following accurate classification of perineal trauma according to the guidelines of the Royal College of Obstetricians and Gynaecologists...
  26. ncbi Cancer core distribution in patients diagnosed by extended transperineal prostate biopsy
    Takefumi Satoh
    Department of Urology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
    Urology 66:114-8. 2005
    ..To perform systemic 22-core transperineal ultrasound-guided template prostate biopsies in patients with previous negative transrectal ultrasound-guided prostate biopsy findings and evaluate the cancer core distribution...
  27. pmc Obstetric factors associated with levator ani muscle injury after vaginal birth
    Rohna Kearney
    University College Hospital, London, United Kingdom
    Obstet Gynecol 107:144-9. 2006
    ..To identify obstetric factors associated with development of levator ani injury after vaginal birth...
  28. pmc PErineal Assessment and Repair Longitudinal Study (PEARLS): protocol for a matched pair cluster trial
    Debra E Bick
    King s College London, Florence Nightingale School of Nursing and Midwifery, James Clerk Maxwell Building, 57 Waterloo Road, London, UK
    BMC Pregnancy Childbirth 10:10. 2010
    ..Implementation of a standardised training package to support effective perineal management practices could reduce perineal pain and other related postnatal morbidity for a substantial number of women...
  29. ncbi Sutured perineal omentoplasty after abdominoperineal resection for adenocarcinoma of the lower rectum
    E De Broux
    Department of General and Digestive Surgery, Hospital Saint Antoine AP HP, Pierre et Marie Curie University, Paris, France
    Dis Colon Rectum 48:476-81; discussion 481-2. 2005
    ..This study was designed to describe and evaluate the efficacy of sutured perineal omentoplasty on perineal wound healing after abdominoperineal resection for adenocarcinoma of the lower rectum...
  30. pmc Dendritic fibromyxolipoma in the right inguinal and perineum regions: a case report and review of the literature
    Xing Jian Zhang
    Department of General Surgery, The 175th Hospital of PLA, Southeast Hospital Affiliated to Xiamen University, NO, 269, Zhanghua Middle Road, Zhangzhou 363000 Fujian Province, China
    Diagn Pathol 8:157. 2013
    A 32-year-old woman presented with a slow-growing, painless, subcutaneous lesion in the right inguinal and perineum regions. The mass was 24.0 cm × 10.5 cm × 5.0 cm in size, well circumscribed, mobile, and rubbery...
  31. ncbi Fecal and urinary incontinence after vaginal delivery with anal sphincter disruption in an obstetrics unit in the United States
    Dee E Fenner
    Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA
    Am J Obstet Gynecol 189:1543-9; discussion 1549-50. 2003
    ....
  32. ncbi Use of vacuum-assisted closure for healing of a persistent perineal sinus following panproctocolectomy: report of a case
    M Yousaf
    Department of Surgery, Altnagelvin Area Hospital, Londonderry, United Kingdom
    Dis Colon Rectum 47:1403-7; discussion 1407-8. 2004
    ..This technique was successfully used in the management of a perineal sinus, which occurred after proctectomy for rectal cancer developing on a background of inflammatory bowel disease and preoperative radiotherapy...
  33. ncbi Outcomes of immediate vertical rectus abdominis myocutaneous flap reconstruction for irradiated abdominoperineal resection defects
    Charles E Butler
    Department of Plastic Surgery, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    J Am Coll Surg 206:694-703. 2008
    ..Many surgeons are reluctant to use VRAM flaps unless primary closure is not possible...
  34. ncbi Reconstruction of the perineum following extralevator abdominoperineal excision for carcinoma of the lower rectum: a systematic review
    J D Foster
    Yeovil District Hospital, Yeovil, UK
    Colorectal Dis 14:1052-9. 2012
    ..We report an evidence-based systematic review of published data on the outcome of perineal reconstruction following ELAPE for low rectal carcinoma, comparing the use of tissue flap and biological mesh techniques...
  35. ncbi Explorable three-dimensional digital model of the female pelvis, pelvic contents, and perineum for anatomical education
    Aimée Sergovich
    Department of Anatomy and Cell Biology, Corps for Research of Instructional and Perceptual Technologies, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada
    Anat Sci Educ 3:127-33. 2010
    ..The model includes the pelvic girdle, organs of the pelvic cavity, surrounding musculature, the perineum, neurovascular structures, and the peritoneum. Each structure can be controlled separately (e.g...
  36. ncbi Adult perineal sarcomas
    S R Grobmyer
    Department of Surgery, Memorial-Sloan Kettering Cancer Center, New York, New York, USA
    J Surg Oncol 77:101-4. 2001
    ..CONCLUSIONS: Aggressive therapy and follow-up beginning with wide excision can be associated with long-term survival in adults with primary perineal sarcoma...
  37. ncbi Laparoscopic total mesorectal excision
    A J Pikarsky
    Department of Colorectal Surgery, Cleveland Clinic Florida, 2950 Cleveland Clinic Blvd, Weston, FL 33331, USA
    Surg Endosc 16:558-62. 2002
    ..In this review, we assess the adequacy of laparoscopic total mesorectal excision, describe the techniques (both anterior resection and abdominoperineal resection), and discuss their potential advantages...
  38. ncbi First Australian trial of the birth-training device Epi-No: a highly significantly increased chance of an intact perineum
    Gabor T Kovacs
    Birralee Birthing Unit, Box Hill Hospital, Box Hill Medical School, Monash University, Victoria, Australia
    Aust N Z J Obstet Gynaecol 44:347-8. 2004
    ..A German report suggested significantly better outcomes in terms of perineal care, second stage length and neonatal outcome for users of Epi-No...
  39. ncbi Vulvoperineal Crohn's disease: response to metronidazole
    Aida Khaled
    Department of Dermatology, Charles Nicolle Hospital, Tunis, Tunisia
    Skinmed 8:240-1. 2010
    ..The patient was started on metronidazole 1 g/d. After 6 months of treatment, there was an almost-complete healing of ulcerations (Figure 2). Treatment was well-tolerated...
  40. ncbi Primary perineal wound closure after preoperative radiotherapy and abdominoperineal resection has a high incidence of wound failure
    Kelli M Bullard
    Department of Surgery, Division of Colon and Rectal Surgery, University of Minnesota, Minneapolis, Minnesota, USA
    Dis Colon Rectum 48:438-43. 2005
    ..Despite its efficacy, preoperative radiation therapy may inhibit healing and contribute to wound complications. This study was designed to evaluate perineal wound complications after abdominoperineal resection...
  41. ncbi Soft-tissue tumours of the perineum
    K A Behranwala
    Sarcoma and Melanoma Unit, Royal Marsden NHS Trust, London, UK
    Eur J Surg Oncol 28:437-42. 2002
    ..We present our experience of perineal tumours better to characterize and define the natural history of this condition...
  42. ncbi Aggressive angiomyxoma of the female pelvis and perineum: a case series
    P M Magtibay
    Department of Obstetrics and Gynecology, Mayo Clinic, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA
    Int J Gynecol Cancer 16:396-401. 2006
    ..These tumors are benign, locally infiltrative mesenchymal neoplasms with a predilection for the female pelvis and perineum and a tendency to recur...
  43. ncbi Circumferential resection margin involvement after laparoscopic abdominoperineal excision for rectal cancer
    I Raftopoulos
    University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Colorectal Dis 14:431-7. 2012
    ..This study aimed to evaluate circumferential resection margin (CRM) involvement in patients with rectal adenocarcinoma after laparoscopic abdominoperineal excision (APR)...
  44. ncbi Median raphe cysts of the perineum in children
    Lucas Krauel
    Pediatric Surgery Department, Hospital Sant Joan de Deu, University of Barcelona, Barcelona, Spain
    Urology 71:830-1. 2008
    Median raphe cysts of the perineum are uncommon congenital lesions of the male genitalia. They can be found all the way from the distal penis and scrotum toward the perineum in a midline position...
  45. ncbi Accessory breast in the perineum
    Somprakas Basu
    Department of Surgery, North Bengal Medical College and Hospital, Sushruta Nagar, Darjeeling 734432, India
    Trop Doct 33:245. 2003
    A rare case of functional accessory breast in the perineum presenting in labour is reported. It showed a well-formed nipple and pregnancy induced changes. The organ was completely excised postpartum...
  46. ncbi Increased blood loss in upright birthing positions originates from perineal damage
    A de jonge
    Department of General Practice, Women Studies Medicine, University Medical Centre St Radboud, Nijmegen, The Netherlands
    BJOG 114:349-55. 2007
    ..To assess whether the risk of severe blood loss is increased in semi-sitting and sitting position, and if so, to which extent blood loss from perineal damage is responsible for this finding...
  47. ncbi Descending perineum syndrome: are abdominal hysterectomy and bowel habits linked?
    Filippo Pucciani
    Dipartimento di Area Critica Medico Chirurgica, Sezione di Clinica Chirurgica Generale e Discipline Chirurgiche, Unità di Colon Proctologia, Universita di Firenze, Firenze Careggi, Italy
    Dis Colon Rectum 48:2094-9. 2005
    This retrospective study evaluates the effect of abdominal hysterectomy on patients affected by descending perineum syndrome.
  48. ncbi A prospective observational study on tears during vaginal delivery: occurrences and risk factors
    Ellen Samuelsson
    Perinatal Center, Department of Obstetrics and Gynecology, Sahlgrenska University Hospital Ostra, 416 85 Goteborg, Sweden
    Acta Obstet Gynecol Scand 81:44-9. 2002
    ..To ascertain the occurrence and distribution of various types of I-IV degree tears, during childbirth, and analyze risk factors for perineal II degree tears...
  49. ncbi Pedicled gracilis myocutaneous flap for treatment of recalcitrant hidradenitis suppurativa of the groin and perineum
    N S Solanki
    Clinical School of Medicine, Cambridge University, Cambridge, UK
    J Wound Care 18:111-2. 2009
    ..Use of this flap achieved immediate closure of a complex groin wound following a radical excision. The patient recovered quickly and was pleased with the aesthetic results, while there was no sign of recurrence at three-month follow-up...
  50. ncbi Relaxin of prostatic origin might be linked to perineal hernia formation in dogs
    Gert W Niebauer
    Clinic for Surgery, University of Veterinary Medicine, Veterinaerplatz 1, Vienna, Austria, A 1210
    Ann N Y Acad Sci 1041:415-22. 2005
    ..Relaxin of prostatic origin, therefore, is possibly a local factor in connective tissue weakening and subsequently in perineal hernia formation...
  51. ncbi Perineal trauma and postpartum perineal morbidity in Asian and non-Asian primiparous women giving birth in Australia
    Hannah Dahlen
    Royal Hospital for Women and University of Technology, Sydney, Australia
    J Obstet Gynecol Neonatal Nurs 37:455-63. 2008
    ..To describe the postpartum perineal morbidity of primiparous women who had a vaginal birth and compare outcomes between Asian and non-Asian women in the first 2 days following the birth and at 6 and 12 weeks postpartum...
  52. ncbi Is severe perineal damage increased in women with prior anal sphincter injury?
    Heather Edwards
    Department of Obstetrics and Gynecology, Temple University Hospital, Philadelphia, PA 19140, USA
    J Matern Fetal Neonatal Med 19:723-7. 2006
    ..This retrospective chart review seeks to examine the risk of recurrence of obstetric anal sphincter lacerations...
  53. ncbi Postpartum sexual functioning and its relationship to perineal trauma: a retrospective cohort study of primiparous women
    L B Signorello
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Am J Obstet Gynecol 184:881-8; discussion 888-90. 2001
    ..retrospective cohort design in 3 groups of primiparous women after vaginal birth: Group 1 (n = 211) had an intact perineum or first-degree perineal tear; group 2 (n = 336) had second-degree perineal trauma; group 3 (n = 68) had third- ..
  54. ncbi [Risk factors for 3rd and 4th degree perineal ruptures during delivery]
    V Kalis
    Gynekologicko porodnická klinika LF UK a FN, Plzen
    Ceska Gynekol 70:30-6. 2005
    ..Summary of the mutual relationship between vaginal delivery and anal incontinence...
  55. ncbi The use of porcine small intestinal submucosa as a biomaterial for perineal herniorrhaphy in the dog
    Melissa R Stoll
    Department of Veterinary Medicine and Surgery, The Comparative Orthopaedic Laboratory, The College of Engineering, University of Missouri, Columbia, MO, USA
    Vet Surg 31:379-90. 2002
    ....
  56. ncbi Fetal head circumference and length of second stage of labor are risk factors for levator ani muscle injury, diagnosed by 3-dimensional transperineal ultrasound in primiparous women
    Dan V Valsky
    Department of Obstetrics and Gynecology, Hadassah Hebrew University Medical Centers, Jerusalem, Israel
    Am J Obstet Gynecol 201:91.e1-7. 2009
    ..We evaluated rate of levator ani muscle (LAM) avulsion among primiparae using 3-dimensional transperineal ultrasound to identify possible risk factors for such trauma...
  57. ncbi Anal sphincter lacerations and upright delivery postures--a risk analysis from a randomized controlled trial
    Daniel Altman
    Pelvic Floor Center, Department of Obstetrics and Gynecology, Karolinska Institute Danderyd Hospital, Stockholm, Sweden
    Int Urogynecol J Pelvic Floor Dysfunct 18:141-6. 2007
    ..To evaluate obstetric sphincter lacerations after a kneeling or sitting position at second stage of labor in a multivariate risk analysis model...
  58. ncbi A Prospective longitudinal evaluation of quality of life after abdominoperineal resection
    Pascal Gervaz
    Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    J Surg Oncol 97:14-9. 2008
    ..Abdominoperineal resection (APR) is a disfiguring procedure, frequently associated with significant urogenital dysfunction. The aim of this prospective study was to repeatedly assess quality of life (QoL) 1, 6, and 12 months after APR...
  59. ncbi [Immediate and long term complications of episiotomy]
    B Langer
    Département de gynécologie obstétrique, Hopital de Hautepierre, Avenue Moliere, 67098 Strasbourg Cedex
    J Gynecol Obstet Biol Reprod (Paris) 35:1S59-1S67. 2006
    ..The objective of this review was to describe the complications of episiotomy...
  60. ncbi Rupture of the sphincter ani: the recurrence rate in second delivery
    Ibtesam Elfaghi
    Department of Obstetrics and Gynaecology, Helsingborg Hospital, Sweden
    BJOG 111:1361-4. 2004
    ..Injury to the genital tract sustained during childbirth can lead to transient or protracted morbidity. Attention should be paid to avoidable risk factors that can cause this complication...
  61. ncbi Episiotomy and increase in the risk of obstetric laceration in a subsequent vaginal delivery
    Marianna Alperin
    Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee Womens Hospital, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Obstet Gynecol 111:1274-8. 2008
    ..To examine whether episiotomy at first vaginal delivery increases the risk of spontaneous obstetric laceration in the subsequent delivery...
  62. ncbi The pros and cons of suctioning at the perineum (intrapartum) and post-delivery with and without meconium
    Sithembiso Velaphi
    Department of Pediatrics, University of the Witwatersrand, Johannesburg, South Africa
    Semin Fetal Neonatal Med 13:375-82. 2008
    ..Although depressed infants born through MSAF are at risk of developing MAS, there is no evidence that endotracheal suctioning of these infants reduces MAS...
  63. ncbi Risk factors for perineal wound complications following abdominoperineal resection
    Caprice K Christian
    Department of Surgery, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Dis Colon Rectum 48:43-8. 2005
    ..Perineal wound complications are common following abdominoperineal resection. This study investigates the factors contributing to these complications...
  64. ncbi [Prevalence of urinary incontinence and pelviperineal rehabilitation during the postpartum in a cohort of primipara and secondipara patients]
    L Driul
    Clinica di Ginecologia ed Ostetricia, Universita Degli Studi di Udine, 33100 Udine, Italia
    Minerva Ginecol 61:89-95. 2009
    ..The aim of the present study was to evaluate the prevalence of urinary incontinence and pelviperineal disorders in the local context, and also that of pelviperineal rehabilitation...
  65. ncbi Incidence, severity, and determinants of perineal pain after vaginal delivery: a prospective cohort study
    Alison J Macarthur
    Department of Anesthesia, University of Toronto, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, Canada M5G 1X5
    Am J Obstet Gynecol 191:1199-204. 2004
    ..Four hundred forty-four women were followed up, including women with an intact perineum (n=84), first-/second-degree tears (n=220), episiotomies (n=97), or third-/fourth-degree tears (n=46)...
  66. ncbi Does perineal suturing make a difference? The SUNS trial
    Valerie E M Fleming
    School of Nursing, Midwifery and Community Health, Glasgow Caledonian University, UK
    BJOG 110:684-9. 2003
    ..To examine differences in outcome between primiparous women who do and who do not have suturing to first or second degree perineal lacerations sustained during spontaneous vaginal births after 37 weeks of gestation...
  67. ncbi [Defecation problems following radical perineal prostatectomy. A prospective study]
    R Kirschner-Hermanns
    Urologische Klinik, Universitatsklinikum, RWTH, Aachen
    Urologe A 42:677-84. 2003
    ..The true incidence of bowel symptoms prior to radical prostatectomy, as evaluated by a differentiated questionnaire, is unknown. We therefore performed a prospective study on patients who were scheduled for radical perineal prostatectomy...
  68. ncbi Maternal position at midwife-attended birth and perineal trauma: is there an association?
    Barbara Soong
    Department of Maternal Fetal Medicine, Mater Mothers Hospital, Brisbane, Queensland, Australia
    Birth 32:164-9. 2005
    ..This study aimed to examine the association between maternal position at birth and perineal outcome in women who had a midwife-attended, spontaneous vaginal birth and an uncomplicated pregnancy at term...
  69. ncbi One-stage posttraumatic bladder reconstruction and soft-tissue coverage of the lower abdomen or perineum
    Chih Wei Wu
    Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Chang Gung University and Medical College, Taoyuan, Taiwan
    Ann Plast Surg 64:65-8. 2010
    ..on pelvis may be complicated by urinary bladder ruptures and soft-tissue avulsion of the lower abdominal wall or perineum. With retraction of the avulsed abdominal wall or perineum, as well as bladder tissue loss secondary to trauma or ..
  70. ncbi Prostate cancer distribution in patients diagnosed by transperineal template-guided saturation biopsy
    Gregory S Merrick
    Schiffler Cancer Center, Wheeling Hospital and Wheeling Jesuit University, Wheeling, WV 26003 6300, USA
    Eur Urol 52:715-23. 2007
    ..To determine the prostate cancer incidence, anatomic distribution, Gleason score profile, and tumor burden in patients diagnosed by transperineal template-guided saturation biopsy (TTSB)...
  71. ncbi Hands on or hands off the perineum: a survey of care of the perineum in labour (HOOPS)
    Ruben Trochez
    The Chilterns, Women s Health, Southmead Hospital, Bristol, BS10 5NB, UK
    Int Urogynecol J 22:1279-85. 2011
    There seems to be a temporal association between increasing use of "hands off" the perineum in labour and reduced use of episiotomy with an increasing rate of anal sphincter injuries...
  72. ncbi A novel concept for the surgical anatomy of the perineal body
    Ahmed Shafik
    Department of Surgery and Experimental Research, Faculty of Medicine, Cairo University, Cairo, Egypt
    Dis Colon Rectum 50:2120-5. 2007
    ..We investigated the hypothesis that perineal body is the site across which perineal muscles pass uninterrupted from one side to the other...
  73. ncbi Comparative effectiveness of perineal versus retropubic and minimally invasive radical prostatectomy
    Sandip M Prasad
    Division of Urologic Surgery, Brigham and Women s Hospital, Boston, Massachusetts, USA
    J Urol 185:111-5. 2011
    ..In our population based study we compared the use and outcomes of perineal radical prostatectomy vs retropubic and minimally invasive radical prostatectomy...
  74. ncbi Obstetric perineal injury: risk factors and strategies for prevention
    Colm O'Herlihy
    Department of Obstetrics and Gynecology, University College Dublin, National Maternity Hospital, Dublin, Ireland
    Semin Perinatol 27:13-9. 2003
    ..Injury can be prevented or minimized by enhancing uterine contractility during first labors, optimizing perineal repair technique, and by appropriate postnatal assessment of symptomatic women...
  75. ncbi Extensive transperineal template biopsies of prostate: modified technique and results
    Simon R J Bott
    Department of Urology, Royal Surrey County Hospital, Guildford, Surrey, United Kingdom
    Urology 68:1037-41. 2006
    ..To describe the modified technique and results of extensive transperineal template prostate biopsies in men with a high risk of prostate cancer in whom repeated transrectal biopsies are not diagnostic...
  76. ncbi Birth position, accoucheur, and perineal outcomes: informing women about choices for vaginal birth
    Allison Shorten
    Faculty of Health and Behavioural Sciences, University of Wollongong, New South Wales, Australia
    Birth 29:18-27. 2002
    ....
  77. ncbi Factors related to genital tract trauma in normal spontaneous vaginal births
    Leah L Albers
    College of Nursing, and in the Department of Obstetrics and Gynecology, School of Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131 5688, USA
    Birth 33:94-100. 2006
    ..The purpose of this investigation was to identify maternal and clinical factors related to genital tract trauma in normal, spontaneous vaginal births...
  78. ncbi Impact of a novel, extended approach of perineal radical prostatectomy on surgical margins in localized prostate cancer
    Shogo Inoue
    Department of Urology, Shimane University School of Medicine, Izumo, Japan
    BJU Int 106:44-8. 2010
    ..Therapy (case series) Level of Evidence 4...
  79. ncbi The anatomic radical perineal prostatectomy: an outcomes-based evolution
    Michael J Harris
    Northern Institute of Urology, 4100 Park Forest Drive, Suite 200, Traverse City, MI 49684, USA
    Eur Urol 52:81-8. 2007
    ..Perineal prostatectomy is modified to incorporate contemporary surgical ideas, including preservation of cavernosal nerve bundles, sphincteric urethra at the prostatic apex, and the bladder neck...
  80. ncbi Radical perineal prostatectomy for treatment of localized prostate cancer in obese and nonobese patients: a matched control study
    Benjamin K Yang
    Division of Urologic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Urology 67:990-5. 2006
    ..To compare the perioperative outcomes of severely obese and nonobese patients undergoing radical perineal prostatectomy (RPP)...
  81. ncbi Role of transperineal six-core prostate biopsy in patients with prostate-specific antigen level greater than 10 ng/mL and abnormal digital rectal examination findings
    Lorenzo G Luciani
    Department of Urology, S M Misericordia Hospital University of Udine, Udine, Italy
    Urology 67:555-8. 2006
    ..Recent studies have suggested that the six-core biopsy is inadequate for the diagnosis of prostate cancer; however, it remains controversial whether an increased number of cores is justified in all patients...
  82. ncbi The practice of episiotomy in public hospitals in Hong Kong
    K W Lam
    Department of Obstetrics and Gynaecology, University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong
    Hong Kong Med J 12:94-8. 2006
    ..To review the use of episiotomy during vaginal delivery in Hong Kong public hospitals...
  83. ncbi Proximal-type epithelioid sarcoma: report of two cases in the perineum: differential diagnosis and review of soft tissue tumors with epithelioid and/or rhabdoid features
    Eduardo Alfredo Zevallos-Giampietri
    Department of Pathology, King Khali Hospital, Jeddah, Saudi Arabia
    Appl Immunohistochem Mol Morphol 13:221-30. 2005
    ..magnetic resonance imaging showed a 14-cm nonencapsulated tumor involving the soft tissues of the inner thigh and perineum, as well as metastasis in right inguinal and retroperitoneal lymph nodes...
  84. ncbi Breeding status affects motoneuron number and muscle size in naked mole-rats: recruitment of perineal motoneurons?
    Marianne Seney
    Department of Psychology and Center for Neuroendocrine Studies, University of Massachusetts, Amherst, Massachusetts 01003, USA
    J Neurobiol 66:1354-64. 2006
    ..We propose that small, relatively undifferentiated cells are recruited to the pool of large Onuf's nucleus motoneurons when subordinate naked mole-rats become breeders...
  85. ncbi Test-retest and intra-observer repeatability of two-, three- and four-dimensional perineal ultrasound of pelvic floor muscle anatomy and function
    Ingeborg Hoff Braekken
    Department of Sports Medicine, Norwegian School of Sport Sciences, P O Box 4014, Ulleval Stadion, 0806 Oslo, Norway
    Int Urogynecol J Pelvic Floor Dysfunct 19:227-35. 2008
    ..56, 0.59 and 0.51, respectively. Perineal ultrasound is a reliable method for measuring most of the tested parameters of morphology and function of the PFMs...
  86. ncbi Perineal lipomas associated with anorectal malformations
    Tomas Wester
    Department of Paediatric Surgery, University Children s Hospital, 751 85, Uppsala, Sweden
    Pediatr Surg Int 22:979-81. 2006
    ..Excision is best performed at time of anorectal reconstruction. Although our experience is limited, bowel function seems to be compromised by these lesions...
  87. ncbi Meshless repair of perineal hernia after abdominoperineal resection: case report
    F H Remzi
    Cleveland Clinic Foundation, Department of Colorectal Surgery, A 30, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA
    Tech Coloproctol 9:142-4. 2005
    ..The patient recovered well and after 35 months of follow-up, there was no evidence of hernia recurrence. When mesh placement is not feasible, this bladder mobilization technique can replace it...
  88. ncbi Multiple polypoid basal cell carcinomas on the perineum of a patient with basal cell nevus syndrome
    Steven Q Wang
    Department of Medicine, Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    J Am Acad Dermatol 57:S36-7. 2007
    ..patient with basal cell nevus syndrome (BCNS) who developed multiple polypoid basal cell carcinomas (PBCC) in the perineum. PBCC is a rare variant of nodular BCCs. Clinically, PBCCs mimic acrochordons...
  89. ncbi Surgisis mesh repair of a postsacrectomy perineal hernia along with posterior proctosigmoidectomy for concomitant stricture
    Abdullah A Al-Haddad
    Department of Surgery, Division of Colon and Rectal Surgery, DeWitt Daughtry Family Department of Surgery, Miller School of Medicine, University of Miami, Miami, Florida 33136, USA
    Am Surg 73:1129-32. 2007
    ..We additionally present a review of the literature and treatment of this rare disease...
  90. ncbi Primary perineal posterior hernia: an abdominoperineal approach for mesh repair of the pelvic floor
    Mara R Salum
    Department of Gastroenterological Surgery, UNIFESP, SaoPaulo, SP, Brazil
    Clinics (Sao Paulo) 60:71-4. 2005
    ..Long-term follow-up has shown no recurrence of the condition and normal bowel function. It is concluded that primary perineal hernia can be repaired by a combined surgical approach, by using prosthetic material...
  91. ncbi Rectus flap reconstruction decreases perineal wound complications after pelvic chemoradiation and surgery: a cohort study
    David B Chessin
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Surg Oncol 12:104-10. 2005
    ..Our purpose was to determine the effect of rectus abdominus myocutaneous (RAM) flap reconstruction on perineal wound morbidity in this population...
  92. ncbi Surgical management of perineal masses in patients with anorectal malformations
    Donald B Shaul
    Childrens Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA 90027, USA
    J Pediatr Surg 40:188-91. 2005
    ..The aim of this study was to review the outcome of surgical management of various types of perineal masses encountered in patients with anorectal malformations (ARM)...
  93. ncbi Phenotypic variation in functional disorders of defecation
    Adil E Bharucha
    Division of Gastroenterology and Hepatology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
    Gastroenterology 128:1199-210. 2005
    ..Our aim was to characterize phenotypic variability in constipated patients by anorectal assessments...
  94. ncbi Prenatal sonographic diagnosis of congenital perineal skin tag: case report and review of the literature
    Angelika Bord
    Department of Obstetrics and Gynecology, Hadassah University Hospital Mt Scopus, Jerusalem, Israel
    Prenat Diagn 26:1065-7. 2006
    ..Skin tags, or acrochordons, are benign, soft, fleshy tumors that are composed of hyperplastic epidermis covering a dermal connective tissue stalk...
  95. ncbi Perineal descent and levator ani hernia: a dynamic magnetic resonance imaging study
    Susan L Gearhart
    Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Dis Colon Rectum 47:1298-304. 2004
    ..This study was designed to identify any specific symptoms and/or physical findings associated with these hernias...
  96. ncbi Racial differences in severe perineal lacerations after vaginal delivery
    Jay Goldberg
    Department of Obstetrics and Gynecology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Am J Obstet Gynecol 188:1063-7. 2003
    ..The purpose of this study was to determine the relationship between maternal race and rates of third- and fourth-degree laceration after vaginal delivery...
  97. ncbi Perineal rectosigmoidectomy (Altemeier's procedure): a review of physiology, technique and outcome
    A P Zbar
    Department of Medicine and Clinical Research, Queen Elisabeth Hospital, University of West Indies, Martindales Road, St Michael, Barbados
    Tech Coloproctol 6:109-16. 2002
    ..The lack of prospective randomized data regarding this perineal approach makes clinical interpretation difficult at the present time...
  98. ncbi Continuous versus interrupted perineal repair with standard or rapidly absorbed sutures after spontaneous vaginal birth: a randomised controlled trial
    Christine Kettle
    Academic Department of Obstetrics and Gynaecology, Women and Children s Division, City General Site, Stoke on Trent ST4 6QG, UK
    Lancet 359:2217-23. 2002
    Trauma to the perineum is a serious and frequent problem after childbirth, with about 350000 women each year in the UK needing sutures for perineal injury after spontaneous vaginal delivery, and many millions more worldwide...
  99. ncbi How to treat the persistent perineal sinus after rectal excision
    John H Pemberton
    Division of Colon and Rectal Surgery, Mayo Clinic and Mayo Foundation, East 6 A 200 First Street SW, Rochester, MN 55905, USA
    Colorectal Dis 5:486-9. 2003
    ..e. perineum), varies between simple closure on one hand and creation of complex gluteal and rectus abdominus flaps on the ..
  100. ncbi Postoperative perineal hernia
    Alaa S O Abdul Jabbar
    Department of Surgery MBC 40, King Faisal Specialist Hospital and Research Centre, PO Box 3354, Riyadh 11211, Kingdom of Saudi Arabia
    Hernia 6:188-90. 2002
    ..This report describes a patient with a large perineal hernia after an abdominoperineal resection. The spectrum of perineal hernias, the aetiology, and the different techniques of surgical repair are discussed...
  101. ncbi Perineal stapled prolapse resection: a new procedure for external rectal prolapse
    Roland Scherer
    Center for Colorectal and Pelvic Floor Surgery, Waldfriede Hospital, Berlin, Germany
    Dis Colon Rectum 51:1727-30. 2008
    ..This technique has been modified to the perineal stapled prolapse resection. The surgical technique and the preliminary results of the new procedure for external rectal prolapse are presented...

Research Grants46

  1. Neuroprosthesis development utilizing afferent neural activity recorded with non-
    TIMOTHY M BRUNS; Fiscal Year: 2012
    ..Unlike other neural structures, cell bodies are packed closely under the DRG perineum, making it an ideal candidate for obtaining activity from individual cells without using penetrating electrodes...
  2. Genetics of Reproductive Senescence
    Marc Tatar; Fiscal Year: 2010
    ..understand human reproductive aging because we can accurately determine their life-long menstrual behavior from perineum turgescence and, like humans, are non-seasonal breeders...
  3. ACCEPTABILITY AND SAFETY STUDY OF JANESWAY FEMALE CONDOM
    Ron Frezieres; Fiscal Year: 2000
    ..S. today. The commercially available product is anchored by an external ring that only partially covers the perineum and can be accidentally pushed into the vagina during intercourse...
  4. Visualization and real-time dosimetry for prostate brachytherapy using ultrasound
    Septimiu Salcudean; Fiscal Year: 2007
    ..The seeds are loaded into hollow needles which are then inserted into the prostate through the perineum using a marked insertion template...
  5. DO 3-D COMPUTER MODELS OF ANATOMY ENHANCE LEARNING?
    James Johnson; Fiscal Year: 2002
    ..The subject of these learning packages will be the female pelvis and perineum. These areas of anatomy are particularly difficult to demonstrate by dissection and increasingly important for ..
  6. MOLECULAR MECHANISM FEMALE STRESS URINARY INCONTINENCE
    Tom Lue; Fiscal Year: 2002
    ..by using pregnant rats and placed a intravaginal balloon under traction to direct the force to the levators and perineum to simulate the human situation...
  7. NEUROMUSCULAR INJURY AND RECOVERY AFTER VAGINAL DELIVERY
    Alison Weidner; Fiscal Year: 2003
    ..perineal muscle function, 3) studying the effects of epidural analgesia on striated muscle of maternal pelvis and perineum, and 4) comparing magnetic resonance imaging (MRI) studies of the pelvic anatomy of these women and correlating ..
  8. MECHANISMS OF SEXUAL DIFFERENTIATION IN NERVOUS SYSTEM
    NANCY FORGER; Fiscal Year: 2001
    ..Motoneurons of the spinal nucleus of the bulbocavernosus (SNB) of rodents innervate striated muscles of the perineum. The number of SNB motoneurons and the survival of SNB target muscles depend on exposure to androgen during ..
  9. STEROID CONTROL OF MOTONEURON NUMBER AND CONNECTIVITY
    DALE SENGELAUB; Fiscal Year: 1990
    ..These nuclei innervate muscles of the perineum, and both the nuclei and the muscles they innervate are present in males but reduced or absent in females...
  10. Clinical Measures to Lower Genital Tract Trauma at Birth
    Leah Albers; Fiscal Year: 2004
    ..A randomized trial of 1200 low-risk women will compare three strategies on the likelihood of an intact perineum after birth, with control for confounding variables (maternal age and parity, birth position, style of pushing, ..
  11. Assessment of Penile Autonomic Innervation
    Claire Yang; Fiscal Year: 2007
    ..The ability to detect cavernous neuropathy is relevant to the evaluation of erectile dysfunction, as well as the development of disease-specific treatments for neurogenic erectile dysfunction. [unreadable] [unreadable]..
  12. Race Differences in Female UI: Epidemiology and Biology
    John DeLancey; Fiscal Year: 2005
    ..Knowledge of these factors can then provide the basis for risk factor identification and the development of preventive strategies appropriate to different racial groups. ..
  13. Epidemiology and Mechanisms of Fecal Incontinence
    Adil Bharucha; Fiscal Year: 2005
    ..abstract_text> ..
  14. Novel Application of Infection Control Strategies to Limit Transmission of ESBL'S
    Ebbing Lautenbach; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  15. Impact of Fiber Fermentation on Fecal Incontinence
    Donna Bliss; Fiscal Year: 2007
    ..Differences among the measures of the groups after supplementation will be compared after controlling for baseline values of these measures using ANCOVA. ..
  16. Breeding status and delayed motoneuron maturation in a eusocial mammal
    Marianne Seney; Fiscal Year: 2008
    ..This information could be used to develop treatments for degenerative diseases characterized by loss or atrophy of motoneurons, such as amyotrophic lateral sclerosis (ALS). [unreadable] [unreadable] [unreadable]..
  17. BOTULINUM TOXIN THERAPY FOR INTERSTITIAL CYSTITIS/CHRON*
    Mary FitzGerald; Fiscal Year: 2007
    ..abstract_text> ..
  18. QUINOLONE RESISTANCE IN NOSOCOMIAL URINARY INFECTIONS
    Ebbing Lautenbach; Fiscal Year: 2004
    ....
  19. URINE LOSS AND PROLAPSE IN NUNS AND THEIR PAROUS SISTERS
    GUNHILDE BUCHSBAUM; Fiscal Year: 2003
    ..A matched pair logistic regression will be performed to obtain an adjusted estimate of the impact of familiality and vaginal delivery in UT and POP, taking into account other risk factors. ..
  20. Patient-Oriented Models for Urinary Function in Women
    Linda Brubaker; Fiscal Year: 2008
    ..unreadable] b. To model urinary storage in health and disease [unreadable] c. To model urinary emptying in health and diseas [unreadable] [unreadable]..
  21. ALPHA-2 ADRENERGIC CONTROL OF COLONIC FUNCTION IN IBS
    Michael Camilleri; Fiscal Year: 2007
    ..abstract_text> ..
  22. ALPHA 2 ADRENERGIC CONTROL IN IRRITABLE BOWEL SYNDROME
    Michael Camilleri; Fiscal Year: 2008
    ..Significance: This project will characterize pharmacogenetic mechanisms determining the response to clonidine through studies of candidate genes that control alpha2-adrenoreceptor function and norepinephrine transport in IBS. ..
  23. Quinolone resistant E coli in long term care facilities
    Ebbing Lautenbach; Fiscal Year: 2009
    ..abstract_text> ..
  24. MALE UROGENITAL FUNCTION AND CHRONIC SPINAL CORD INJURY
    Charles Hubscher; Fiscal Year: 2009
    ..Parallel electrophysiological, neuroanatomical and behavioral studies are once again proposed. ..
  25. Raising Literacy and Capacity for Incontinence and Skin Care in Dementia
    Donna Bliss; Fiscal Year: 2009
    ....
  26. Function of the Urethra in Continent Women
    Kimberly Kenton; Fiscal Year: 2008
    ..Normative ranges will be calculated for EMG, current perception thresholds, and urethral pressures for Caucasian and African American women. These data can then be used by other centers as reference data. [unreadable] [unreadable]..
  27. Enteral vs. IV Feeding: Effect on Mucosal Immunity
    Kenneth A Kudsk; Fiscal Year: 2010
    ....
  28. Estrogen: Neuroprotection in the Perimenopause
    Anne M Etgen; Fiscal Year: 2010
    ..These experiments will provide new information on the potential for hormone therapy instituted during the perimenopausal transition to protect the brain from damage due to global ischemia. ..
  29. Shoulder Pain in Spinal Cord Injury (SCI): A Longitudinal Study
    Sara J Mulroy; Fiscal Year: 2010
    ..MANOVA will be employed to compare the biomechanical parameters of WCP for the shoulder pain and pain-free groups. ..
  30. Cannabinoid Mechanisms in Human Gastrointestinal Motor and Sensory Functions
    MICHAEL L CAMILLERI; Fiscal Year: 2010
    ..These actions may be relevant to develop new treatments for IBS. The studies will also provide further understanding of the potential of medications like medical marijuana on stomach function that may be relevant to appetite control. ..
  31. Molecular Analysis of Scarless Fetal Wound Healing
    Sandeep Kathju; Fiscal Year: 2007
    ..With these complementary approaches we hope to thereby arrive at a broad understanding of the gene patterns controlling both fetal and adult wound healing, and identify gene products/pathways critical to both. ..
  32. INTERVENTIONS FOR SCI SHOULDER FUNCTION IN WHEELCHAIRS
    Sara Mulroy; Fiscal Year: 2004
    ..Statistical significance of the findings will be determined by repeated measures MANOVA analyses with grouping factors for SCI level and exercise/control groups. ..
  33. A Female Mouse Model to Study Recurrent Genital Herpes
    Margaret Parr; Fiscal Year: 2002
    ..abstract_text> ..
  34. MECHANISMS OF SEXUAL DIFFERENTIATION IN NEURAL SYSTEMS
    NANCY FORGER; Fiscal Year: 2004
    ....
  35. Sensory Testing in Subjects with Interstitial Cystitis
    Mary FitzGerald; Fiscal Year: 2004
    ..abstract_text> ..
  36. ROLE OF HYALURONAN IN INFLAMMATORY BOWEL DISEASE
    Scott Strong; Fiscal Year: 2005
    ..abstract_text> ..
  37. EPIDEMIOLOGY OF CHRONIC PELVIC PAIN
    J Clemens; Fiscal Year: 2005
    ..abstract_text> ..
  38. Treatment Investigation for Posterior Prolapse
    GEOFFREY CUNDIFF; Fiscal Year: 2005
    ..All subjects will be followed for a total of three years. ..
  39. NEUROENDOCRINE BASES OF REPRODUCTIVE BEHAVIOR
    ANNE ETGEN; Fiscal Year: 2006
    ..Specific Aim 4 will determine how IGF-1 acutely potentiates a1-adrenoceptor signaling in the HYP-POA of E2-treated females and whether this is important for reproductive behavior. ..
  40. Functional analysis of C. perfringens epsilon toxin
    J Songer; Fiscal Year: 2006
    ..This information can be used to model the mode of action of ETX, and to define regions of the molecule that could be targeted for immunoprophylaxis and treatment. ..
  41. Clinical Impact of Quinolone-Resistant E.coli carriage
    Ebbing Lautenbach; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  42. Female Pelvic Floor Disorders and Sexual Functions
    Victoria Handa; Fiscal Year: 2007
    ..This powerful combination will provide the candidate with the necessary skills and experience to become a successful, independently funded investigator. [unreadable] [unreadable]..
  43. STEROID HORMONES--BRAIN AND BEHAVIOR
    ANNE ETGEN; Fiscal Year: 2007
    ..These studies will provide novel[unreadable] insights into the cellular and molecular mechanisms by which ovarian[unreadable] sterioids act in the brain and to produce predictable behavioral[unreadable] changes. ..
  44. Beaumont Interstitial Cystitis Clinical Research Network
    Kenneth Peters; Fiscal Year: 2007
    ..Adverse events and complications will be monitored. Ancillary studies as agreed upon by the ICCRN will be carried out in conjunction with the clinical trial. ..
  45. Chronic Prostatitis Collaborative Research Network
    Anthony Schaeffer; Fiscal Year: 2007
    ..abstract_text> ..
  46. ANORECTAL MANIFESTATIONS OF FEMALE PELVIC FLOOR DISORDER
    Adil Bharucha; Fiscal Year: 2002
    ..abstract_text> ..