skull base

Summary

Summary: The inferior region of the skull consisting of an internal (cerebral), and an external (basilar) surface.

Top Publications

  1. doi Neuro-ophthalmologic manifestations of benign anterior skull base lesions
    Mark Hornyak
    Department of Neurosurgery, University of Utah, Salt Lake City, UT 84132, USA
    Postgrad Med 121:103-14. 2009
  2. doi Endoscopic endonasal skull base surgery: analysis of complications in the authors' initial 800 patients
    Amin B Kassam
    Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    J Neurosurg 114:1544-68. 2011
  3. ncbi Tumefactive fibroinflammatory lesion of the neck with progressive invasion of the meninges, skull base, orbit, and brain
    A I Holodny
    Department of Radiology, New Jersey Medical School, University Hospital, 150 Bergen Street, Newark, NJ 07103, USA
    AJNR Am J Neuroradiol 22:876-9. 2001
  4. doi Nasoseptal flap reconstruction of high flow intraoperative cerebral spinal fluid leaks during endoscopic skull base surgery
    Adam M Zanation
    Department of Otolaryngology Head and Neck Surgery, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599, USA
    Am J Rhinol Allergy 23:518-21. 2009
  5. doi Endoscopic pedicled nasoseptal flap reconstruction for pediatric skull base defects
    Rupali N Shah
    Department of Otolaryngology Head and Neck Surgery, University of North Carolina Hospitals, Chapel Hill, North Carolina 27599, USA
    Laryngoscope 119:1067-75. 2009
  6. doi High incidence of optic canal involvement in tuberculum sellae meningiomas: rationale for aggressive skull base approach
    Burak Sade
    Brain Tumor and Neuro Oncology Center, Neurological Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Surg Neurol 72:118-23; discussion 123. 2009
  7. doi Endoscopic skull base reconstruction of large dural defects: a systematic review of published evidence
    Richard J Harvey
    Department of Otolaryngology and Skull Base Surgery, St Vincent s Hospital, Sydney, New South Wales, Australia
    Laryngoscope 122:452-9. 2012
  8. doi Reconstruction techniques in skull base surgery
    Filippo Gagliardi
    Department of Neurosurgery, San Raffaele Scientific Institute, Vita Salute University, Milan, Italy
    J Craniofac Surg 22:1015-20. 2011
  9. doi Cranial base growth in patients with Down syndrome: a longitudinal study
    Juan J Alio
    Prophylaxis, Odonthopediatrics and Orthodontics Department, Universidad Complutense de Madrid, Universidad Complutense de Madrid, Madrid, Spain
    Am J Orthod Dentofacial Orthop 133:729-37. 2008
  10. doi Nasoseptal flap takedown and reuse in revision endoscopic skull base reconstruction
    Adam M Zanation
    Department of Otolaryngology Head and Neck Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Laryngoscope 121:42-6. 2011

Detail Information

Publications262 found, 100 shown here

  1. doi Neuro-ophthalmologic manifestations of benign anterior skull base lesions
    Mark Hornyak
    Department of Neurosurgery, University of Utah, Salt Lake City, UT 84132, USA
    Postgrad Med 121:103-14. 2009
    Visual disturbance is a common presenting symptom of anterior skull base lesions. These lesions cause deterioration in visual acuity, restriction of the visual field, or reduction of ocular mobility...
  2. doi Endoscopic endonasal skull base surgery: analysis of complications in the authors' initial 800 patients
    Amin B Kassam
    Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    J Neurosurg 114:1544-68. 2011
    ..of endoscopic endonasal approaches, albeit in the early stages, represents part of the continuous evolution of skull base surgery...
  3. ncbi Tumefactive fibroinflammatory lesion of the neck with progressive invasion of the meninges, skull base, orbit, and brain
    A I Holodny
    Department of Radiology, New Jersey Medical School, University Hospital, 150 Bergen Street, Newark, NJ 07103, USA
    AJNR Am J Neuroradiol 22:876-9. 2001
    ..The lesion caused destruction of the skull base and a subdural hematoma...
  4. doi Nasoseptal flap reconstruction of high flow intraoperative cerebral spinal fluid leaks during endoscopic skull base surgery
    Adam M Zanation
    Department of Otolaryngology Head and Neck Surgery, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599, USA
    Am J Rhinol Allergy 23:518-21. 2009
    ..The goals of this study are to prospectively evaluate the nasoseptal flap and high-risk cerebral spinal fluid (CSF) leak variables...
  5. doi Endoscopic pedicled nasoseptal flap reconstruction for pediatric skull base defects
    Rupali N Shah
    Department of Otolaryngology Head and Neck Surgery, University of North Carolina Hospitals, Chapel Hill, North Carolina 27599, USA
    Laryngoscope 119:1067-75. 2009
    ..radioanatomic analysis of computed tomography (CT) scans to determine limitations of the nasoseptal flap in pediatric skull base reconstruction and to describe clinical outcomes after using the nasoseptal flap in six pediatric patients.
  6. doi High incidence of optic canal involvement in tuberculum sellae meningiomas: rationale for aggressive skull base approach
    Burak Sade
    Brain Tumor and Neuro Oncology Center, Neurological Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Surg Neurol 72:118-23; discussion 123. 2009
    ..Current literature on TSMs underemphasizes the significance of OCI by the tumor. In this study, we aimed to document the incidence of OCI, its management using a SBT, and its significance with relation to the visual outcome...
  7. doi Endoscopic skull base reconstruction of large dural defects: a systematic review of published evidence
    Richard J Harvey
    Department of Otolaryngology and Skull Base Surgery, St Vincent s Hospital, Sydney, New South Wales, Australia
    Laryngoscope 122:452-9. 2012
    Systematically review the outcomes of endoscopic endonasal techniques to reconstruct large skull base defects (ESBR)...
  8. doi Reconstruction techniques in skull base surgery
    Filippo Gagliardi
    Department of Neurosurgery, San Raffaele Scientific Institute, Vita Salute University, Milan, Italy
    J Craniofac Surg 22:1015-20. 2011
    ..A variety of endoscopic pedicled mucosal flaps within the nasal cavity have also been described. The different reconstruction techniques are described and discussed in terms of indications, advantages, and drawbacks...
  9. doi Cranial base growth in patients with Down syndrome: a longitudinal study
    Juan J Alio
    Prophylaxis, Odonthopediatrics and Orthodontics Department, Universidad Complutense de Madrid, Universidad Complutense de Madrid, Madrid, Spain
    Am J Orthod Dentofacial Orthop 133:729-37. 2008
    ..The purpose of this study was to assess the growth of the cranial base in a sample of patients diagnosed with Down syndrome (DS)...
  10. doi Nasoseptal flap takedown and reuse in revision endoscopic skull base reconstruction
    Adam M Zanation
    Department of Otolaryngology Head and Neck Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Laryngoscope 121:42-6. 2011
    ..a description of the techniques and limitations of nasoseptal flap takedown and reuse during second-stage and revision endoscopic skull base surgery and review the institutional experience with the use of this reconstructive technique.
  11. doi Long-term outcomes of fractionated stereotactic radiotherapy for intracranial skull base benign meningiomas in single institution
    Shunsuke Onodera
    Department of Radiation Medicine, Hokkaido University Graduate School of Medicine, North 15, West 7, Kita ku, Sapporo 060 8638, Japan
    Jpn J Clin Oncol 41:462-8. 2011
    ..the outcome of linac-based fractionated stereotactic radiotherapy over the last 10 years for intracranial skull base benign meningiomas in patients who were inoperable, who had residual tumors with some components of high mitotic ..
  12. doi Extended endoscopic endonasal approach to the skull base
    O L Arbolay
    Department of Neurosurgery, Hermanos Ameijeiras Hospital, La Habana City, Cuba
    Minim Invasive Neurosurg 52:114-8. 2009
    Different approaches to the skull base have been developed through the sphenoidal sinus. Traditional boundaries of the trans-sphenoidal approach can be extended in antero-posterior and lateral planes...
  13. doi Temporalis muscle flap for reconstruction of skull base defects
    Jesse E Smith
    Department of Otolaryngology Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Head Neck 32:199-203. 2010
    The temporalis muscle flap (TMF) is a valuable reconstructive technique utilized in a variety of challenging defects. However, its use for repair of skull base defects is less commonly reported.
  14. ncbi Radiology of skull base neoplasms
    D D Durden
    Department of Radiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA
    Otolaryngol Clin North Am 34:1043-64, vii. 2001
    Computed tomography (CT) and magnetic resonance (MR) imaging are used routinely to stage skull base neoplasms preoperatively, define the extent of the tumor, identify perineural spread, plan surgery and radiation therapy, and evaluate the ..
  15. pmc Detecting plasma Epstein-Barr virus DNA to diagnose postradiation nasopharyngeal skull base lesions in nasopharyngeal carcinoma patients: a prospective study
    Fa Ya Liang
    Department of Head and Neck Surgery, Sun Yat Sen Memorial Hospital, Sun Yat Sen University, Guangzhou, Guangdong 510120, P R China
    Chin J Cancer 31:142-9. 2012
    The diagnosis of postradiation nasopharyngeal skull base lesions in petients with nasopharyngeal carcinoma (NPC) is still a tough problem in clinical practice. An early and accurate diagnosis is important for subsequent management...
  16. ncbi Stereotactic proton beam therapy of skull base meningiomas
    F J Vernimmen
    Department of Radiation Oncology, Tygerberg Hospital, Tygerberg, South Africa
    Int J Radiat Oncol Biol Phys 49:99-105. 2001
    To review outcomes for patients with skull base meningiomas treated using the stereotactic proton beam at the National Accelerator Center (NAC), Republic of South Africa.
  17. ncbi Fibrous dysplasia involving the skull base and temporal bone
    L R Lustig
    Department of Otolaryngology Head and Neck Surgery, The Johns Hopkins University, JHOC Sixth Floor, 601 N Caroline St, Baltimore, MD 21287 0910, USA
    Arch Otolaryngol Head Neck Surg 127:1239-47. 2001
    To gain a broader appreciation of the clinical presentation, operative treatment, and outcome of patients with fibrous dysplasia involving the skull base.
  18. doi Janus flap: bilateral nasoseptal flaps for anterior skull base reconstruction
    Gurston G Nyquist
    Department of Otorhinolaryngology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY, USA
    Otolaryngol Head Neck Surg 142:327-31. 2010
    Large dural defects after extended endoscopic endonasal skull base resections require meticulous reconstruction to prevent a cerebrospinal fluid leak postoperatively...
  19. ncbi A comparison of craniofacial morphology in patients with and without facial asymmetry--a three-dimensional analysis with computed tomography
    T G Kwon
    Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyungpook National University, Samduck 2 Ga, Jung Gu, Daegu 700 421, South Korea
    Int J Oral Maxillofac Surg 35:43-8. 2006
    ..The asymmetric condyle position was found to be associated with skull base characteristics...
  20. ncbi Intraoperative facial motor evoked potential monitoring with transcranial electrical stimulation during skull base surgery
    Charles C J Dong
    Division of Neurosurgery, Department of Surgery, University of British Columbia, Vancouver, BC, Canada
    Clin Neurophysiol 116:588-96. 2005
    ....
  21. ncbi A revolution in skull base surgery: the quality of life matters!
    James I Ausman
    Surg Neurol 65:635-6. 2006
  22. ncbi World Health Organization Grades II and III meningiomas are rare in the cranial base and spine
    Burak Sade
    Brain Tumor Institute, The Cleveland Clinic, Cleveland, Ohio 44195, USA
    Neurosurgery 61:1194-8; discussion 1198. 2007
    ..This study was undertaken to assess a possible relationship between the tumor location and the incidence of World Health Organization (WHO) Grades II and III meningiomas...
  23. ncbi First clinical evaluation of the navigated controlled drill at the lateral skull base
    M Hofer
    BMBF Innovation Center Computer Assisted Surgery ICCAS, University of Leipzig, Germany
    Stud Health Technol Inform 132:171-3. 2008
    Surgery on the lateral skull base puts delicate structures at risk. To support the surgeon in identifying and protecting the risk structures the principle of Navigated Control (NC) can be used for preventing iatrogenic injuries...
  24. doi Prevention and management of vascular injuries in endoscopic surgery of the sinonasal tract and skull base
    C Arturo Solares
    Department of Otolaryngology, Medical College of Georgia, Augusta, GA 30907, USA
    Otolaryngol Clin North Am 43:817-25. 2010
    ..These techniques have been further expanded to manage skull base pathologies. This expansion has been facilitated by a better understanding of the endonasal skull base anatomy...
  25. doi Anterior and middle cranial fossa skull base reconstruction using microvascular free tissue techniques: surgical complications and functional outcomes
    Ernest S Chiu
    Tulane Health Sciences Center, New Orleans, LA, USA
    Ann Plast Surg 60:514-20. 2008
    Surgical ablation for oncologic disease requiring skull base resection can result in both facial disfigurement and a complex wound defect with exposed orbital content, oral cavity, bone, and dural lining...
  26. doi Prevention and management of skull base injury
    Esther Kim
    Division of Rhinology, Department of Otolaryngology, Vanderbilt University Medical Center, 7209 Medical Center East South Tower, 1215 21st Avenue South, Nashville, TN 37232 8605, USA
    Otolaryngol Clin North Am 43:809-16. 2010
    b>Skull base defects and injuries are rare, but may occur during endoscopic sinus surgery, as a result of facial trauma, or as a result of tumors in the anterior cranial fossa...
  27. ncbi Inflammatory pseudotumour involving the skull base and cervical spine
    Y S Cho
    Department of Otorhinolaryngology-Head and Neck Surgery, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea
    J Laryngol Otol 115:580-4. 2001
    ..IPT involving the skull base and cervical spine is distinctly rare and usually indistinguishable from aggressive neoplasms or infection...
  28. doi Endoscopic management of skull base defects associated with persistent pneumocephalus following previous open repair: a preliminary report
    David W Clark
    Department of Otorhinolaryngology Head and Neck Surgery, Texas Sinus Institute, Texas Skull Base Institute, University of Texas at Houston Medical School, Houston, TX 77030, USA
    Otolaryngol Head Neck Surg 142:820-6. 2010
    To describe the management of anterior skull base defects in patients who present with pneumocephalus after previous open neurosurgical intervention.
  29. doi Endoscopic endonasal anatomy and approaches to the anterior skull base: a neurosurgeon's viewpoint
    Bashar Abuzayed
    Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    J Craniofac Surg 21:529-37. 2010
    The objective of this study was to review the endoscopic anatomy of the anterior skull base, defining the pitfalls of endoscopic endonasal approaches to this region...
  30. ncbi [Transnasal endoscopic approaches to the cranial base]
    Tomasz Lyson
    Klinika Neurochirurgii, Uniwersytet Medyczny w Białymstoku, Białystok
    Neurol Neurochir Pol 47:63-73. 2013
    ..The authors of this contribution use most of these approaches in their endoscopic skull base surgery...
  31. doi Intraoperative facial nerve motor evoked potential monitoring during skull base surgery predicts long-term facial nerve function outcomes
    Masafumi Fukuda
    Department of Neurosurgery, Brain Research Institute, University of Niigata, Japan
    Neurol Res 33:578-82. 2011
    This study was designed to clarify whether facial nerve motor evoked potentials (FNMEPs) elicited by transcranial electrical stimulation during skull base surgery are useful for predicting long-term facial nerve function.
  32. doi Pulsed laser-induced liquid jet for skull base tumor removal with vascular preservation through the transsphenoidal approach: a clinical investigation
    Yoshikazu Ogawa
    Department of Neurosurgery, Kohnan Hospital, Nagamachiminami, Taihaku ku, Sendai, Miyagi, Japan
    Acta Neurochir (Wien) 153:823-30. 2011
    ..To overcome these problems, we have developed a pulsed laser-induced liquid jet (LILJ) system to dissect tumor tissue with preservation of fine blood vessels within deep and narrow working spaces and evaluated its utility and safety...
  33. pmc The natural evolution of endoscopic approaches in skull base surgery: robotic-assisted surgery?
    I Dallan
    Otorhinolaryngologic Unit, University of Insubria, Italy
    Acta Otorhinolaryngol Ital 31:390-4. 2011
    ..This is particularly intriguing in skull base regions...
  34. doi Computed tomography of the anterior skull base in Kallmann syndrome reveals specific ethmoid bone abnormalities associated with olfactory bulb defects
    Luigi Maione
    Universite Paris Sud, Faculte de Medecine Paris Sud, Assistance Publique Hopitaux de Paris, Hopital de Bicetre, Service d endocrinologie et des maladies de la reproduction, Le Kremlin Bicetre, France
    J Clin Endocrinol Metab 98:E537-46. 2013
    ..Kallmann syndrome (KS) is characterized by congenital hypogonadotropic hypogonadism (CHH) and an impaired sense of smell related to defective development of the olfactory system...
  35. doi Clinical utility of the inferior turbinate flaps in the reconstruction of the nasal septum and skull base
    Dong Hoon Lee
    Department of Otolaryngology Head and Neck Surgery, Chonnam National University Medical School and Hwasun Hospital, Hwasun, South Korea
    J Craniofac Surg 23:e322-6. 2012
    ..been used for the repair of the septal perforation, and the PPITF has been used for the reconstruction of the skull base. Because of the technical difficulties of endoscopic preparation of the ITF, clinical studies on endoscopic ..
  36. ncbi Intracranial infection as a common complication following war missile skull base injury
    B Splavski
    Division of Neurosurgery, Osijek University Hospital, Osijek, Croatia
    Injury 31:233-7. 2000
    ..therapy, and early surgery in the management of intracranial infection following war missile penetrating skull base injury. There were 21 skull base missile injuries treated surgically in a 4-year period...
  37. ncbi History of endoscopic skull base surgery: its evolution and current reality
    Daniel M Prevedello
    Department of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville, Virginia, USA
    J Neurosurg 107:206-13. 2007
    ..between otorhinolaryngologists and neurosurgeons has produced a new subspecialty of "endoscopic skull base surgery...
  38. doi Endoscopic endonasal versus open transcranial resection of anterior midline skull base meningiomas
    Ricardo J Komotar
    Department of Neurological Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    World Neurosurg 77:713-24. 2012
    To assess the advantages and limitations of the endoscopic endonasal approach to anterior skull base meningiomas, a minimally invasive approach that avoids extensive bone drilling, brain retraction, and manipulation of nerves and critical ..
  39. doi Mucocele after transnasal endoscopic repair of traumatic anterior skull base fistula in children
    Benjamin Verillaud
    Department of Pediatric Otolaryngology, Head and Neck Surgery, Hopital d Enfants Armand Trousseau, APHP and University Paris VI, 26 Avenue Arnold Netter, 75571 Paris Cedex 12, France
    Int J Pediatr Otorhinolaryngol 75:1137-42. 2011
    To report the long-term sinonasal complications after endoscopic repair of anterior skull base fractures in children. This study describes mucocele formation in 6 patients treated endoscopically for posttraumatic CSF fistulae...
  40. doi Anteriorly based inferior turbinate flap for endoscopic skull base reconstruction
    Ziv Gil
    The Head and Neck Surgery Unit, Department of Otolaryngology Head and Neck Surgery, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel Aviv University, Israel Tel Aviv, Israel
    Otolaryngol Head Neck Surg 146:842-7. 2012
    In the absence of the nasal septal flap, there is limited ability to reconstruct the anterior skull base because of the paucity of alternative intranasal vascularized flaps...
  41. ncbi Orthopedic cervical headgear with an expanded inner bow in class II correction
    M Kirjavainen
    Department of Pedodontics and Orthodontics, University of Helsinki, Finland
    Angle Orthod 70:317-25. 2000
    ..The cephalometric analysis suggested that the observed improvement of the occlusion was due to an inhibition of forward growth of the maxilla and anterior downward rotation of the palate...
  42. ncbi Endoscopic endonasal surgery (EES) in skull base repairs and CSF leakage
    C Bachert
    ENT-Department Head and Neck Surgery, University Hospital Ghent, Belgium
    Acta Otorhinolaryngol Belg 54:179-89. 2000
    This report aims to summarise the current role of Endoscopic Endonasal Surgery (EES) for skull base and cerebrospinal fluid (CSF) leakage repair, to provide some guidelines for the clinical diagnosis and technical procedures of repair, to ..
  43. ncbi Real-time computed tomography image update for endoscopic skull base surgery
    B A Woodworth
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, Pennsylvania 19104, USA
    J Laryngol Otol 122:361-5. 2008
    ..However, conventional computer-aided systems do not provide intra-operative updated computed tomography imaging. We describe the technical aspects of the xCAT, a new intra-operative mobile volume computed tomography scanner...
  44. doi Efficacy of the pedicled nasoseptal flap without cerebrospinal fluid (CSF) diversion for repair of skull base defects: incidence of postoperative CSF leaks
    Jean Anderson Eloy
    Department of Otolaryngology Head and Neck Surgery, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, NJ 07103, USA
    Int Forum Allergy Rhinol 2:397-401. 2012
    The advances in endoscopic skull base surgery have led to the resection of increasingly larger cranial base lesions and the creation of larger skull base defects with the potential for increased postoperative high-flow cerebrospinal fluid ..
  45. ncbi Endoscopic endonasal surgery of the midline skull base: anatomical study and clinical considerations
    Luigi M Cavallo
    Division of Neurosurgery, Department of Neurological Sciences, Universita degli Studi di Napoli Federico II, Naples, Italy
    Neurosurg Focus 19:E2. 2005
    The midline skull base is an anatomical area that extends from the anterior limit of the cranial fossa down to the anterior border of the foramen magnum...
  46. doi Inferior turbinate pedicle flap for endoscopic skull base defect repair
    Richard J Harvey
    Department of Otolaryngology Skull Base Surgery, St Vincent s Hospital, Darlinghurst, Sydney, NSW 2010, Australia
    Am J Rhinol Allergy 23:522-6. 2009
    Endoscopic skull base reconstruction (ESBR) is an important advance in the management of skull base defects...
  47. doi Endoscopic endonasal repair of anterior skull base non-traumatic cerebrospinal fluid leaks, meningoceles, and encephaloceles
    Gurston G Nyquist
    Department of Otorhinolaryngology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York 10065, USA
    J Neurosurg 113:961-6. 2010
    ..endonasal approach has become the preferred technique for CSF leak and encephalocele repair of the anterior skull base. The purpose of this study is to identify patient characteristics; review adjunctive perioperative treatments, ..
  48. doi One thousand endoscopic skull base surgical procedures demystifying the infection potential: incidence and description of postoperative meningitis and brain abscesses
    Yuriko Kono
    Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Infect Control Hosp Epidemiol 32:77-83. 2011
    Endonasal endoscopic skull base surgery (ESBS) is perceived as having a high risk of infection because it is performed through the sinuses, which are not sterile...
  49. ncbi Skull base trauma: diagnosis and management
    Madjid Samii
    Department of Neurosurgery, Hannover College of Medicine, Carl Neuberg Strasse 1, D 30625 Hannover, Germany
    Neurol Res 24:147-56. 2002
    ..Extensive dural laceration and severe neurovascular damage may accompany skull base injuries...
  50. doi Gamma knife surgery for skull base meningiomas
    Robert M Starke
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg 116:588-97. 2012
    b>Skull base meningiomas are challenging tumors owing in part to their close proximity to important neurovascular structures...
  51. ncbi Endoscopic management of anterior skull base encephaloceles
    Mark E Boseley
    Department of Otolaryngology Head and Neck Surgery, University of Cincinnati Medical Center, Cincinnati, Ohio, USA
    Ann Otol Rhinol Laryngol 113:30-3. 2004
    Encephaloceles are relatively rare phenomena produced by the protrusion of brain and dura through an anterior skull base defect. Although they can occur as congenital defects, encephaloceles can also present after trauma...
  52. doi 10 pearls for safe endoscopic skull base surgery
    Madeleine R Schaberg
    Department of Otolaryngology, Weill Medical College of Cornell University, New York Presbyterian Hospital, 1305 York Avenue, Fifth Floor, New York, NY 10065, USA
    Otolaryngol Clin North Am 43:945-54. 2010
    The introduction of the endoscopic endonasal approach for the management of lesions of the skull base has produced a paradigm shift in the way complicated lesions of this complex anatomic location are managed...
  53. doi Latissimus dorsi free flap reconstruction of anterior skull base defects
    Angelique Girod
    Head and Neck Oncologic Surgery Unit, Institut Curie, 26 Rue d Ulm, 75005 Paris, France
    J Craniomaxillofac Surg 40:177-9. 2012
    Surgery of extensive skull base tumour results of a defect of soft and hard tissue and dura. Free flap reconstruction provides tissue to restore the defect and separate the intracranial content from the bacterial flora of the nasal fossae...
  54. doi Enabling an unimpeded surgical approach to the skull base in patients with cranial hyperostosis, exemplarily demonstrated for craniometaphyseal dysplasia
    Philipp Juergens
    Department of Cranio Maxillofacial Surgery, University Hospital Basel, University of Basel, Switzerland
    J Neurosurg 115:528-35. 2011
    ..Skull bone more than 50 mm thick in some regions was reduced to physiological thickness. The patient was thus in a stage that neurosurgical interventions could be performed with a regular risk within a reasonable time of treatment...
  55. doi Mucocele rate after endoscopic skull base reconstruction using vascularized pedicled flaps
    Benjamin S Bleier
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Rhinol Allergy 25:186-7. 2011
    Postoperative cerebrospinal fluid leak is a significant risk after endoscopic skull base surgery. Recently, novel reconstructive techniques using vascularized pedicled mucosal flaps have been applied to decrease this potential risk...
  56. doi Prevertebral corridor: posterior pathway for reconstruction of the ventral skull base
    Abdullah Durmaz
    Department of Otorhinolaryngology and Head and Neck Surgery, Gulhane Military Medical School, Ankara, Turkey
    J Craniofac Surg 22:848-53. 2011
    ..flaps, such as the pericranial and temporoparietal fascia flaps, are currently used for reconstruction of skull base defects after endoscopic endonasal surgery whenever local vascularized flaps, such as the nasoseptal flap, are ..
  57. doi Navigated surgery at the lateral skull base and registration and preoperative imagery: experimental results
    Florian Kral
    Department of Otorhinolaryngology, Innsbruck Medical University, Anichstr 35, 6020 Innsbruck, Austria
    Arch Otolaryngol Head Neck Surg 137:144-50. 2011
    To assess factors that affect the accuracy of navigated surgery at the human lateral skull base, including the choice of registration procedures and preoperative computed tomography (CT) section thickness, and to compare target ..
  58. ncbi Nasopharyngeal carcinoma with skull base invasion and hydrocephalus: a case report
    Chih Jen Wang
    Department of Neurosurgery, Kaohsiung Medical University, Kaohsiung, Taiwan
    Kaohsiung J Med Sci 18:582-4. 2002
    We describe a case of nasopharyngeal carcinoma (NPC) with diffuse skull base bony destruction, resulting in obstructive hydrocephalus...
  59. ncbi Parapharyngeal neuroglial heterotopia extending through the skull base in a neonate with airway obstruction
    Thierry A G M Huisman
    Department of Diagnostic Imaging, University Hospital Zurich, CH 8032 Zurich, Switzerland
    J Pediatr Surg 42:1764-7. 2007
    ..Preoperative identification of intracranial extension is essential for planning surgery to prevent postoperative cerebrospinal fluid leaks or possible meningitis...
  60. doi Localization and infliction pattern of iatrogenic skull base defects following endoscopic sinus surgery at a teaching hospital
    Klaus Bumm
    Department of Otorhinolaryngology, Head and Neck Surgery, Friedrich Alexander University Erlangen Nuremberg, Waldstrasse 1, D 91054 Erlangen, Germany
    Auris Nasus Larynx 36:671-6. 2009
    ..We present our results of over 14 years of experience from endoscopic repair of CSF rhinorrhea with long-term follow-up...
  61. ncbi Fully endoscopic expanded endonasal approach treating skull base lesions in pediatric patients
    Amin Kassam
    Minimally Invasive endoNeurosurgery Center, University of Pittsburgh School of Medicine, Pennsylvania, USA
    J Neurosurg 106:75-86. 2007
    ..endoscopic approaches to determine their safety and efficacy in the treatment of pediatric patients who harbor skull base lesions...
  62. pmc An integrated system for planning, navigation and robotic assistance for skull base surgery
    Tian Xia
    Department of Computer Science, Johns Hopkins University, Baltimore, MD 21218, USA
    Int J Med Robot 4:321-30. 2008
    We developed an image-guided robot system to provide mechanical assistance for skull base drilling, which is performed to gain access for some neurosurgical interventions, such as tumour resection...
  63. doi Transoral robotic surgery of the skull base: a cadaver and feasibility study
    John Y K Lee
    Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA
    ORL J Otorhinolaryngol Relat Spec 72:181-7. 2010
    The goal of this study was to determine the potential role as well as the current limitations of the da Vinci Surgical System robot in transoral surgery of the skull base.
  64. ncbi Incidence of skull base and orbital erosion in allergic fungal rhinosinusitis (AFRS) and non-AFRS
    Mark D Ghegan
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, USA
    Otolaryngol Head Neck Surg 134:592-5. 2006
    ..To compare the incidence of bony erosion associated with allergic fungal rhinosinusitis (AFRS) with the incidence of bony erosion seen in other types of inflammatory sinusitis...
  65. ncbi Skull base abnormalities in osteogenesis imperfecta: a cephalometric evaluation of 54 patients and 108 control volunteers
    Outi Kovero
    Department of Oral Radiology, Institute of Dentistry, University of Helsinki, Finland
    J Neurosurg 105:361-70. 2006
    ..The head is often abnormally shaped, and changes in skull base anatomy in the form of basilar impression and basilar invagination have been reported...
  66. ncbi Diagnosis and management of skull base osteoradionecrosis after radiotherapy for nasopharyngeal carcinoma
    Xiao ming Huang
    Department of Otolaryngology, The Second Affiliated Hospital, Sun Yat Sen University, Guangzhou, Guangdong, P R China
    Laryngoscope 116:1626-31. 2006
    The objective of this study was to investigate the diagnosis and management of skull base osteoradionecrosis (ORN) after radiotherapy for nasopharyngeal carcinoma (NPC).
  67. ncbi Skull base approaches in the pediatric population
    Ziv Gil
    Skull Base Surgery Unit and the Department of Otolaryngology, Head and Neck Surgery, Tel Aviv Sourasky Medical Center, 6 Weizmann St, Tel Aviv 64239, Israel
    Head Neck 27:682-9. 2005
    This study aimed to examine the surgical, oncologic, and developmental results of infants and children undergoing extirpation of skull base tumors.
  68. ncbi Concomitant fibrous dysplasia and aneurysmal bone cyst of the skull base. Case report and review of the literature
    G F Haddad
    American University of Beirut, New York, N Y, USA
    Pediatr Neurosurg 28:147-53. 1998
    The combination of fibrous dysplasia and aneurysmal bone cyst of the skull base is extremely rare yet it should be recognized, lest the rapid growth of the lesion and the radiological picture lead to the wrong diagnosis of a malignant ..
  69. ncbi Angiogenesis and skin carcinomas with skull base invasion: a case-control study
    Claudio R Cernea
    Department of Head and Neck Surgery, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Head Neck 26:396-400. 2004
    ..In this study, the expression of CD34 in basal cell carcinomas ( BCCs) and squamous cell carcinomas (SCCs) with skull base invasion was compared with that in tumors with good outcome.
  70. doi Skull base osteomyelitis: the effect of comorbid disease on hospitalization
    Vanessa S Rothholtz
    Department of Otolaryngology Head and Neck Surgery, University of California Irvine, Orange, California 92868, USA
    Laryngoscope 118:1917-24. 2008
    b>Skull base osteomyelitis is a rare disease that has a high morbidity and mortality rate if diagnosis and treatment are delayed. Our objective was to perform a more detailed analysis of skull base osteomyelitis in the inpatient population...
  71. ncbi Skull base growth in childhood
    S Sgouros
    Department of Craniofacial Surgery, Birmingham Children s Hospital, Birmingham, UK
    Pediatr Neurosurg 31:259-68. 1999
    While studying skull base changes in craniosynostosis, it became apparent that there is a lack of reference studies quantifying the changes of three-dimensional (3D) parameters of the normal skull base throughout childhood...
  72. doi Phenotypic manifestations and management of hyperostosis cranialis interna, a hereditary bone dysplasia affecting the calvaria and the skull base
    J J Waterval
    Department of Otorhinolaryngology Head and Neck Surgery, Maastricht University Medical Center, Maastricht, The Netherlands
    Am J Med Genet A 152:547-55. 2010
    ..bone disorder that is characterized by endosteal hyperostosis and osteosclerosis of the calvaria and the skull base (OMIM 144755)...
  73. ncbi Central skull base osteomyelitis in patients without otitis externa: imaging findings
    Patrick C Chang
    Department of Radiology, University of California, San Francisco, School of Medicine, San Francisco, CA 94143, USA
    AJNR Am J Neuroradiol 24:1310-6. 2003
    b>Skull base osteomyelitis typically arises as a complication of ear infection in older diabetic patients, involves the temporal bone, and has Pseudomonas aeruginosa as the usual pathogen...
  74. ncbi Prognostic factors in sinonasal tumors involving the anterior skull base
    Carlos Suarez
    Department of Otolaryngology, Hospital Central de Asturias, Celestino Villaamil, S N, 33006 Oviedo, Spain
    Head Neck 26:136-44. 2004
    ..Anterior craniofacial resection is a standardized procedure for the treatment of ethmoid and frontal orbital tumors with intracranial invasion...
  75. ncbi Gamma knife radiosurgery for glomus jugulare tumors: therapeutic advantages of minimalism in the skull base
    Manish S Sharma
    Department of Neurosurgery and Gamma Knife, All India Institute of Medical Sciences, New Delhi 110 029, India
    Neurol India 56:57-61. 2008
    ..Glomus jugulare (GJ) tumors are paragangliomas found in the region of the jugular foramen. Surgery with/without embolization and conventional radiotherapy has been the traditional management option...
  76. ncbi [Reconstruction of traumatic skull base defects with alloplastic, resorbable fleece]
    R O Seidl
    Klinik fur Hals, Nasen, Ohrenheilkunde, Kopf und Halschirurgie, Unfallkrankenhaus Berlin
    HNO 48:753-7. 2000
    Defects of the frontal skull base can be reconstructed with different types of material. Homologous material possibly involves the risk of infection and thus complicated wound healing...
  77. ncbi Treatment of traumatic aneurysms and arteriovenous fistulas of the skull base by using endovascular stents
    G Redekop
    Department of Neurosurgery, The University of British Columbia, Vancouver, Canada
    J Neurosurg 95:412-9. 2001
    ..clinical experience with the use of endovascular stents in the treatment of traumatic vascular lesions of the skull base region...
  78. ncbi Long-term effects of palate repair on craniofacial morphology in patients with unilateral cleft lip and palate
    Yu Fang Liao
    Department of Dentistry, Craniofacial Center, and Sleep Center, Chang Gung Memorial Hospital, Taipei, Taiwan
    Cleft Palate Craniofac J 42:594-600. 2005
    ..To identify the long-term effects of palate repair on craniofacial growth in patients with unilateral cleft lip and palate (UCLP)...
  79. ncbi Craniofacial development in children with unilateral cleft lip and palate
    Servet Doğan
    Ege University School of Dentistry, Department of Orthodontics, Bornova, Izmir, Turkey
    Br J Oral Maxillofac Surg 44:28-33. 2006
    ..01). The profile of the soft tissue was more convex (p<0.001) and the upper lip was thinner than in the children in the control group (p<0.01), and their noses were relatively further backwards and downwards (p<0.01)...
  80. ncbi Long-term effects of clefts on craniofacial morphology in patients with unilateral cleft lip and palate
    Yu Fang Liao
    Department of Dentistry, Craniofacial Center, Chang Gung Memorial Hospital, Taipei, Taiwan
    Cleft Palate Craniofac J 42:601-9. 2005
    ....
  81. ncbi [Comparative study between medieval (12th -14th c.) and modern skulls samples of five cranio-facial measures]
    R Esclassan
    Faculté de Chirurgie Dentaire de Toulouse, sous section Prothèse, Toulouse
    Rev Stomatol Chir Maxillofac 107:17-22. 2006
    ..The aim of this study was to compare cephalometric norms of complete medieval skulls (n=35) with contemporary skulls (n=41), all from the same region, taking five craniofacial measures...
  82. ncbi Dentocraniofacial morphology of 21 patients with unilateral cleft lip and palate: a cephalometric study
    Miranda Corbo
    Department of Maxillofacial Surgery, Queen Fabiola University Children s Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Cleft Palate Craniofac J 42:618-24. 2005
    ....
  83. ncbi Mandibular distraction osteogenesis in hemifacial microsomia: long-term follow-up
    Maria Costanza Meazzini
    Department of Maxillo Facial Surgery, San Gerardo Hospital, University of Milano Bicocca, Monza, Italy
    J Craniomaxillofac Surg 33:370-6. 2005
    ..Prospective, longitudinal, clinical long-term follow-up study of a homogeneous sample of children affected by hemifacial microsomia and treated by mandibular distraction osteogenesis...
  84. ncbi Bite force and maxillofacial morphology in patients with Duchenne-type muscular dystrophy
    Koichiro Ueki
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kanazawa University, Kanazawa, Japan
    J Oral Maxillofac Surg 65:34-9. 2007
    ..The purpose of this study is to evaluate maxillofacial morphology and bite force in patients with severe Duchenne-type myodystrophy...
  85. ncbi Craniofacial morphology in Chinese female twins: a semi-longitudinal cephalometric study
    Jing Peng
    Department of Pediatric Dentistry, Peking University School of Stomatology, Bejing, China
    Eur J Orthod 27:556-61. 2005
    ..01), whilst genetic effects on face height were also significant (P < 0.01). The results suggest that early orthodontic intervention would have a greater influence on the antero-posterior rather than on the vertical plane of growth...
  86. ncbi Class II malocclusion with maxillary protrusion from the deciduous through the mixed dentition: a longitudinal study
    Antonino Antonini
    Department of Orthodontics, University of Florence, Florence, Italy
    Angle Orthod 75:980-6. 2005
    ..Sucking habits appeared to be correlated with the skeletal maxillary protrusion...
  87. ncbi Reconstruction of skull base defects after minimally invasive endoscopic resection of anterior skull base neoplasms
    Jern Lin Leong
    Department of Otolaryngology, Singapore General Hospital, Singapore
    Am J Rhinol 20:476-82. 2006
    ..resection of the cribriform plate during minimally invasive endoscopic resection (MIER) of the anterior skull base neoplasms may result in large anterior skull base defects...
  88. doi Cephalometric findings in patients with Papillon-Lefèvre syndrome
    Naif A Bindayel
    School of Dental Medicine, Tufts University, Boston, Mass, USA
    Am J Orthod Dentofacial Orthop 134:138-44. 2008
    ..The aim of this retrospective study was to investigate the cephalometric findings of patients with PLS...
  89. doi Longitudinal growth changes in untreated subjects with Class II Division 1 malocclusion
    Franka Stahl
    Department of Orthodontics, University of Rostock, Rostock, Germany
    Am J Orthod Dentofacial Orthop 134:125-37. 2008
    ....
  90. doi Accuracy of three-dimensional (3D) craniofacial cephalometric landmarks on a low-dose 3D computed tomograph
    R Olszewski
    Department of Oral and Maxillofacial Surgery, Av Hippocrate 10, Saint Luc University Clinics, Universite Catholique de Louvain, 1200 Brussels, Belgium
    Dentomaxillofac Radiol 37:261-7. 2008
    ..The absorbed dose levels for radiosensitive organs in the maxillofacial region during the exposure for both 3D-CT protocols were also measured...
  91. ncbi Endoscopic cranial base surgery: ready for prime time?
    Daniel M Prevedello
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Clin Neurosurg 54:48-57. 2007
  92. doi The neurocranial and craniofacial morphology in children with solitary median maxillary central incisor (SMMCI)
    F Tabatabaie
    Department of Orthodontics, Institute of Odontology, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
    Orthod Craniofac Res 11:96-104. 2008
    ..The purpose of this study was to describe the neurocranial and craniofacial morphology on profile radiographs of children with single median maxillary central incisor (SMMCI)...
  93. doi Linear accuracy and reliability of cone beam CT derived 3-dimensional images constructed using an orthodontic volumetric rendering program
    Danielle R Periago
    Department of Orthodontic and Pediatric Dentistry, University of Louisville School of Dentistry, Louisville, KY, USA
    Angle Orthod 78:387-95. 2008
    ..To compare accuracy of linear measurements made on cone beam computed tomographic (CBCT) derived 3-dimensional (3D) surface rendered volumetric images to direct measurements made on human skulls...
  94. doi Morphometric investigation in the skulls of young adults. A comparative study between 19th century and modern Italian samples
    Efisio Defraia
    Department of Orthodontics, University of Florence, Florence, Italy
    Angle Orthod 78:641-6. 2008
    ..To test the hypothesis that there are no differences in the shape of the cranial complex between two samples from the same restricted geographical area and separated by almost 150 years...
  95. ncbi Preoperative osseous dysmorphology in unilateral complete cleft lip and palate
    Stephen A Schendel
    Plast Reconstr Surg 120:2114-5. 2007
  96. doi Craniofacial computerized tomography analysis of the midface of patients with repaired complete unilateral cleft lip and palate
    Sunjay Suri
    Discipline of Orthodontics, Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada
    Am J Orthod Dentofacial Orthop 134:418-29. 2008
    ....
  97. ncbi Huge primary myxoma of skull base: a report of an uncommon case
    H Yin
    Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China
    Acta Neurochir (Wien) 149:713-7. 2007
    ..A huge chondrosarcoma, arising from the skull base with extension into the middle cranial fossa and nasal cavity was suspected...
  98. ncbi Paraganglioma of the skull base: a case report
    Murat Unal
    Mersin University School of Medicine, Department of Otolaryngology, Mersin, Turkey
    Auris Nasus Larynx 34:427-30. 2007
    ..woman with paraganglioma arising in the middle and posterior cranial fossa with extended destruction of the skull base and clivus...
  99. ncbi A cephalometric study on craniofacial morphology of Iranian children with beta-thalassemia major
    F Amini
    Department of Orthodontics and Dentofacial Orthopedics, Dental College of Islamic Azad Medical University, Tehran, Iran
    Orthod Craniofac Res 10:36-44. 2007
    ..To study cephalometric and facial features of Iranian children with beta-thalassemia major...
  100. ncbi Craniofacial, craniocervical, and pharyngeal morphology in bilateral cleft lip and palate and obstructive sleep apnea patients
    Barbara C M Oosterkamp
    Department of Orthoontics, University Medical Center, Groningen, The Netherlands
    Cleft Palate Craniofac J 44:1-7. 2007
    ..The aim of this study was to analyze craniofacial, craniocervical, and pharyngeal morphology in surgically treated bilateral cleft lip and palate (BCLP) men, untreated men with obstructive sleep apnea (OSA), and a reference group of men...
  101. ncbi Hypodontia patterns and variations in craniofacial morphology in Japanese orthodontic patients
    Toshiya Endo
    Department of Orthodontics, The Nippon Dental University Niigata Hospital, Niigata, Japan
    Angle Orthod 76:996-1003. 2006
    ..The purpose of this study was to explore the association of hypodontia patterns and variations in craniofacial morphology in Japanese orthodontic patients...

Research Grants72

  1. Pediatric Percutaneous Cochlear Implantation Clinical Validation & Implementation
    Robert F Labadie; Fiscal Year: 2010
    ..PCI reduces CI surgery to a single pass of a drill from the lateral skull base to the cochlea...
  2. Dynamic Vocal Fold Abduction for Bilateral Paralysis
    Michael Broniatowski; Fiscal Year: 2006
    ..Comparing vocal fold positions and the ability to breathe before and during stimulation will establish whether sufficient data are available to pursue clinical applications of laryngeal pacing after bilateral vocal cord paralysis. ..
  3. BONE MATRIX AND BONE RESORPTION
    PAUL ODGREN; Fiscal Year: 2006
    ..We will extend these studies to the synchondroses of the skull base, and use this approach to screen a series of mice with craniofacial and/or osteopetrotic mutations for similar ..
  4. WEARABLE ARTIFICIAL LABYRINTH IN MOTION SICKNESS/VERTIGO
    WESLEY KRUEGER; Fiscal Year: 2005
    ..and in the rehabilitative process in patients with dizziness following vestibular nerve section or removal of a skull base lesion such as acoustic tumor...
  5. PROTON RADIATION THERAPY RESEARCH
    Thomas Delaney; Fiscal Year: 2006
    ..gains in clinical outcomes for a number of disease sites including chondrosarcomas and chordomas of the skull base and cervical spine (95 percent and 50 percent local control, respectively), paranasal sinus tumors (87 percent ..
  6. GENE THERAPY FOR LARYNGEAL PARALYSIS
    Paul Flint; Fiscal Year: 2004
    ..paralysis usually occurs as a result of the surgical removal of tumor involving the head and neck region and skull base. Thyroid surgery, carotid endarterectomy, cardiothoracic and primary lung procedures may also result in ..
  7. An Integrated CT-based Image-Guided Neurosurgical System
    JOSEPH STAYMAN; Fiscal Year: 2005
    ..In many difficult procedures that involve vital structures, like the resection of tumors at the skull base, image-guidance can be a necessity...
  8. Modeling meningioma growth orthotopically in the nude mouse
    Anita Lal; Fiscal Year: 2007
    ..techniques of local drug delivery specifically to meningiomas which grow on the surface of the brain or the skull base, and for investigations into the unique tumor-host interactions of meningiomas...
  9. High-Performance Cone-Beam CT Guidance of Head and Neck Surgery
    Jeffrey H Siewerdsen; Fiscal Year: 2010
    ..in challenging interventional tasks, including ethmoid sinus ablation, trans-sphenoid approach to the CNS, and skull base lesion excision;and 3...
  10. High-Performance Cone-Beam CT Guidance of Head and Neck Surgery
    Jeffrey Siewerdsen; Fiscal Year: 2009
    ..in challenging interventional tasks, including ethmoid sinus ablation, trans-sphenoid approach to the CNS, and skull base lesion excision; and 3...
  11. High-Performance Cone-Beam CT Guidance of Head and Neck Surgery
    Jeffrey Siewerdsen; Fiscal Year: 2007
    ..in challenging interventional tasks, including ethmoid sinus ablation, trans-sphenoid approach to the CNS, and skull base lesion excision; and 3...
  12. Testing Surgery Guided by Molecular Fluorescence Imaging
    Quyen Nguyen; Fiscal Year: 2007
    ..She has also completed a postdoctoral fellowship in Skull Base Surgery at UCSD and now, will expand her combined training in clinical medicine and scientific research through ..
  13. IMPROVING TREATMENT OUTCOMES FOR PATIENTS WITH FACIAL DEFORMITY USING 3D IMAGING
    Lucia Cevidanes; Fiscal Year: 2007
    ..Involvement in these studies will enhance the candidate's prior training in cranio-maxillofacial problems and 3D imaging, while equipping her with tools to perform meaningful studies centered around patient oriented clinical research. ..
  14. Mineral and Mechanical Properties of Bone
    Sarandeep Huja; Fiscal Year: 2005
    ..Future interventional studies will examine the mechanisms for the initial and the long-term adaptive response in material properties of bone. ..
  15. PHENOGENETICS OF SKULL AND BRAIN INTEGRATION IN CRANIOSYNOSTOSIS
    JOAN THERESE RICHTSMEIER; Fiscal Year: 2010
    ....
  16. Gene therapy for treatment of craniofacial dysplasia
    Stephanos Kyrkanides; Fiscal Year: 2004
    ..Completion of this study will aid in the development of novel therapies for the management of genetic disorders. ..
  17. Dysmorphology Core (U24 Core)
    Kenneth Jones; Fiscal Year: 2005
    ..abstract_text> ..
  18. Trigeminal Neuralgia Association 5th National Conference
    Albert Rhoton; Fiscal Year: 2005
    ..abstract_text> ..
  19. Does peripheral localized chronic inflammation predispose to neurodegeneration?
    Stephanos Kyrkanides; Fiscal Year: 2007
    ..Such information is critical to our understanding of the benefits of anti-inflammatory therapy in AD and other conditions and will guide the rational application and development of targeted interventions. ..
  20. Dysmorphology Core - U24
    Kenneth Jones; Fiscal Year: 2007
    ....
  21. Optical imaging of epilepsy in rat and human neocortex
    THEODORE SCHWARTZ; Fiscal Year: 2007
    ..These experiments will set the groundwork for implementing optical recordings in general clinical practice as a novel technique for mapping and predicting human seizures. ..
  22. PHENOGENETICS OF SKULL AND BRAIN INTEGRATION IN CRANIOSYNOSTOSIS
    JOAN RICHTSMEIER; Fiscal Year: 2009
    ....
  23. Recombinant FIV vectors for the delivery of siRNA therapy to joints
    Stephanos Kyrkanides; Fiscal Year: 2007
    ..Emphasis will be given in evaluating COX-2 and/or mPGES-1 expression as they are targets of our FIV(siRNA) therapy over time as well as assessing potential inflammatory responses elicited by this siRNA therapy. ..
  24. Joint degeneration: Somatic mosaic analysis in a transgenic mouse
    Stephanos Kyrkanides; Fiscal Year: 2007
    ....
  25. NEURONAL FUNCTION IN CRANIOFACIAL DEVELOPMENT
    Stephanos Kyrkanides; Fiscal Year: 2004
    ..abstract_text> ..