animal tarsus

Summary

Summary: The region in the hindlimb of a quadruped, corresponding to the human ANKLE.

Top Publications

  1. ncbi IL-1 alpha beta blockade prevents cartilage and bone destruction in murine type II collagen-induced arthritis, whereas TNF-alpha blockade only ameliorates joint inflammation
    L A Joosten
    Department of Rheumatology, University Hospital Nijmegen, The Netherlands
    J Immunol 163:5049-55. 1999
  2. ncbi The surgical management of a fractured tibial tarsal bone in a Kelpie sheepdog
    J A L Maxwell
    Katanning Regional Veterinary Hospital PO Box 273 Katanning, Western Australia 6317
    Aust Vet J 84:40-2. 2006
  3. ncbi Arthroscopic removal and curettage of osteochondrosis lesions on the lateral and medial trochlear ridges of the talus in two dogs
    J L Cook
    Veterinary Medical Teaching Hospital, University of Missouri-Columbia, 65211, USA
    J Am Anim Hosp Assoc 37:75-80. 2001
  4. ncbi The effect of implanting gentamicin-impregnated polymethylmethacrylate beads in the tarsocrural joint of the horse
    K D Farnsworth
    Marion duPont Scott Equine Medical Center and the Department of Pathology, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Leesburg, VA, USA
    Vet Surg 30:126-31. 2001
  5. ncbi Effects of continuous intra-articular infusion of gentamicin on synovial membrane and articular cartilage in the tarsocrural joint of horses
    Timothy B Lescun
    Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47906, USA
    Am J Vet Res 63:683-7. 2002
  6. ncbi Is there a characteristic distal tarsal subchondral bone plate thickness pattern in horses with no history of hindlimb lameness?
    M V Branch
    Centre for Equine Studies, The Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk CB8 7UU, UK
    Equine Vet J 37:450-5. 2005
  7. pmc Morphologic changes associated with functional adaptation of the navicular bone of horses
    V A Bentley
    Comparative Orthopaedic Research Laboratory, School of Veterinary Medicine, University of Wisconsin Madison, Madison, WI 53706, USA
    J Anat 211:662-72. 2007
  8. ncbi A study of ten cases of focal peritarsal infection as a cause of severe lameness in the thoroughbred racehorse: clinical signs, differential diagnosis, treatment and outcome
    R C Pilsworth
    Beaufort Cottage Stables, Newmarket, Suffolk, UK
    Equine Vet J 33:366-70. 2001
  9. ncbi Carpal and fetlock conformation of the juvenile Thoroughbred from birth to yearling auction age
    E M Santschi
    Department of Surgical Sciences, School of Veterinary Medicine, 2015 Linden Drive, Madison, Wisconsin 53706, USA
    Equine Vet J 38:604-9. 2006
  10. ncbi Pitx1 determines the morphology of muscle, tendon, and bones of the hindlimb
    April DeLaurier
    Division of Developmental Biology, National Institute for Medical Research, Mill Hill, London, NW7 1AA, UK
    Dev Biol 299:22-34. 2006

Research Grants

Detail Information

Publications138 found, 100 shown here

  1. ncbi IL-1 alpha beta blockade prevents cartilage and bone destruction in murine type II collagen-induced arthritis, whereas TNF-alpha blockade only ameliorates joint inflammation
    L A Joosten
    Department of Rheumatology, University Hospital Nijmegen, The Netherlands
    J Immunol 163:5049-55. 1999
    ..These results indicate that blocking of IL-1 is a cartilage- and bone-protective therapy in destructive arthritis, whereas the TNF-alpha antagonist has little effect on tissue destruction...
  2. ncbi The surgical management of a fractured tibial tarsal bone in a Kelpie sheepdog
    J A L Maxwell
    Katanning Regional Veterinary Hospital PO Box 273 Katanning, Western Australia 6317
    Aust Vet J 84:40-2. 2006
  3. ncbi Arthroscopic removal and curettage of osteochondrosis lesions on the lateral and medial trochlear ridges of the talus in two dogs
    J L Cook
    Veterinary Medical Teaching Hospital, University of Missouri-Columbia, 65211, USA
    J Am Anim Hosp Assoc 37:75-80. 2001
    ..Removal of all osteochondral fragments (i.e., joint mice) and debridement and curettage of the remaining talar defects were accomplished arthroscopically. Both dogs had excellent short-term outcomes...
  4. ncbi The effect of implanting gentamicin-impregnated polymethylmethacrylate beads in the tarsocrural joint of the horse
    K D Farnsworth
    Marion duPont Scott Equine Medical Center and the Department of Pathology, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Leesburg, VA, USA
    Vet Surg 30:126-31. 2001
    ..CLINICAL RELEVANCE: Temporary intra-articular administration of antibiotic-impregnated PMMA may be an effective way to treat septic joints that require constant high concentrations of antibiotics...
  5. ncbi Effects of continuous intra-articular infusion of gentamicin on synovial membrane and articular cartilage in the tarsocrural joint of horses
    Timothy B Lescun
    Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47906, USA
    Am J Vet Res 63:683-7. 2002
    ..To determine the effects of a continuous intra-articular infusion of gentamicin on the synovial membrane and articular cartilage in the tarsocrural joint of horses...
  6. ncbi Is there a characteristic distal tarsal subchondral bone plate thickness pattern in horses with no history of hindlimb lameness?
    M V Branch
    Centre for Equine Studies, The Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk CB8 7UU, UK
    Equine Vet J 37:450-5. 2005
    ..Thickening of the subchondral bone (SCB) plate has been related to the development of OA, but SCB plate patterns in the equine tarsus have not been documented...
  7. pmc Morphologic changes associated with functional adaptation of the navicular bone of horses
    V A Bentley
    Comparative Orthopaedic Research Laboratory, School of Veterinary Medicine, University of Wisconsin Madison, Madison, WI 53706, USA
    J Anat 211:662-72. 2007
    ....
  8. ncbi A study of ten cases of focal peritarsal infection as a cause of severe lameness in the thoroughbred racehorse: clinical signs, differential diagnosis, treatment and outcome
    R C Pilsworth
    Beaufort Cottage Stables, Newmarket, Suffolk, UK
    Equine Vet J 33:366-70. 2001
    ..It is concluded that, in the majority of cases, prompt treatment with antibiotic therapy, analgesics and forced exercise results in complete resolution of the condition...
  9. ncbi Carpal and fetlock conformation of the juvenile Thoroughbred from birth to yearling auction age
    E M Santschi
    Department of Surgical Sciences, School of Veterinary Medicine, 2015 Linden Drive, Madison, Wisconsin 53706, USA
    Equine Vet J 38:604-9. 2006
    ..There is little information available about conformational changes in the forelimbs of growing foals...
  10. ncbi Pitx1 determines the morphology of muscle, tendon, and bones of the hindlimb
    April DeLaurier
    Division of Developmental Biology, National Institute for Medical Research, Mill Hill, London, NW7 1AA, UK
    Dev Biol 299:22-34. 2006
    ..In contrast, misexpression of Tbx4 in the forelimb does not result in a transformation of limb-type morphology. These results demonstrate that Pitx1, but not Tbx4, determines the morphological identity of hindlimb tissues...
  11. ncbi Diffusion of mepivacaine between adjacent synovial structures in the horse. Part 2: tarsus and stifle
    M R Gough
    Department of Veterinary Clinical Studies, Royal Dick School of Veterinary Studies, University of Edinburgh, Easter Bush Veterinary Centre, Midlothian, Scotland, UK
    Equine Vet J 34:85-90. 2002
    ..Therefore, commonly performed intrasynovial local analgesic techniques in the hindlimb of the horse are not as specific as first thought...
  12. ncbi Oral hyaluronan gel reduces post operative tarsocrural effusion in the yearling Thoroughbred
    B J Bergin
    Rood and Riddle Equine Hospital, Lexington, Kentucky 40580 2070, USA
    Equine Vet J 38:375-8. 2006
    ..Hyaluronan (HA) has been used to treat joint disease via intra-articular, i.v. and oral administration. The efficacy of intra-articular and i.v. use has been evaluated but the oral route has yet to be examined...
  13. ncbi Occult subchondral osseous cyst-like lesions of the equine tarsocrural joint
    José M García-López
    Department of Clinical Sciences, Tufts University School of Veterinary Medicine, North Grafton, MA 01536, USA
    Vet Surg 33:557-64. 2004
    ..To report the clinical signs, diagnosis, management, and outcome of horses with occult sub-chondral osseous cyst-like lesions of the tarsocrural joint...
  14. ncbi Correlation of magnetic resonance images with anatomic features of the equine tarsus
    Rafael Latorre
    Department of Veterinary Anatomy, Veterinary Faculty, University of Murcia, Campus de Espinardo, 30071 Murcia, Spain
    Am J Vet Res 67:756-61. 2006
    ..To correlate anatomic features of the equine tarsus identified in plastinated sections with images obtained via magnetic resonance imaging (MRI)...
  15. ncbi What is your diagnosis? An osseous mass associated with the lateral aspect of the tuber calcaneus, with some degree of soft-tissue swelling
    Tara S Rabuffo
    New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square 19348, USA
    J Am Vet Med Assoc 221:635-6. 2002
  16. ncbi Estimation of genetic parameters for the prevalence of osseous fragments in limb joints of Hanoverian Warmblood horses
    K F Stock
    Institute of Animal Breeding and Genetics, University of Veterinary Medicine Hannover, Hannover, Germany
    J Anim Breed Genet 122:271-80. 2005
    ..75). We conclude from our results that osseous fragments in phalangeal and hock joints are genetically different traits but sex-specific expression of osseous fragments was unlikely...
  17. ncbi What is your diagnosis? Tarsometatarsal subluxation
    William G Marshall
    Hollywood Animal Hospital, 2864 Hollywood Blvd, Hollywood, FL 33020, USA
    J Am Vet Med Assoc 231:1809-10. 2007
  18. ncbi Epiphyseal cartilage canal blood supply to the tarsus of foals and relationship to osteochondrosis
    K Olstad
    The Norwegian School of Veterinary Science, Department of Companion Animal Clinical Sciences, Section for Equine Medicine and Surgery, Oslo, Norway
    Equine Vet J 40:30-9. 2008
    ..Pathological changes in the blood supply to growth cartilage have been implicated in the pathogenesis of osteochondrosis (OC) in horses, but have not been reported using vascular perfusion techniques...
  19. ncbi Imaging diagnosis--Avulsion of the medial collateral ligament of the tarsus in a horse
    Patricia L Rose
    Department of Companion Animals, Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown, Prince Edward Island, Canada C1A 4P3
    Vet Radiol Ultrasound 44:657-9. 2003
  20. ncbi Toe out angle: a functional index for the evaluation of sciatic nerve recovery in the rat model
    Artur S P Varejao
    Department of Pathology and Veterinary Clinics, CETAV, University of Tras os Montes e Alto Douro, Vila Real, Portugal
    Exp Neurol 183:695-9. 2003
    ..Moreover, the TOA provides information on the biomechanical consequences of the external rotation of the foot in the stance phase of walking...
  21. ncbi Nuclear scintigraphic evaluation of the distal tarsal region in normal horses
    Rachel C Murray
    Animal Health Trust, Kentford, Newmarket, CB8 7UU, UK
    Vet Radiol Ultrasound 45:345-51. 2004
    ..Elite showjumpers had significantly higher RU ratio compared with the lower-level riding horses, but no significant alterations in the pattern of RU were detected...
  22. ncbi What is your diagnosis? Avulsion fracture of the plantar aspect of the distal end of the calcaneus and plantar proximal intertarsal subluxation
    Arathi Vinayak
    Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville 37996, USA
    J Am Vet Med Assoc 224:39-40. 2004
  23. ncbi Tibiotarsal arthroscopy. Applications and long-term outcome in dogs
    J Miller
    Virinia Maryland Regional College of Veterinary Medicine, Small Animal Clinical Sciences, Blacksburg, USA
    Vet Comp Orthop Traumatol 21:159-65. 2008
    ..The minimally invasive nature of arthroscopy preserved joint stability while allowing complete examination of the articular cartilage. In most cases long term tibiotarsal DJD advancement was the rule...
  24. ncbi Short-latency crossed inhibitory responses in extensor muscles during locomotion in the cat
    Alain Frigon
    Groupe de Recherche sur le Système Nerveux Central, Department of Physiology, Faculty of Medicine, Universite de Montreal, Montreal, Quebec, Canada
    J Neurophysiol 99:989-98. 2008
    ..Short-latency crossed inhibition in ankle extensors appears to be an integral component of cutaneous reflex pathways in intact cats during locomotion, which could be important in synchronizing EMG bursts in muscles of both legs...
  25. ncbi Scintigraphic evaluation of the distal tarsal region in horses with distal tarsal pain
    Rachel C Murray
    Animal Health Trust, Lanwades Park, Kentford, Newmarket CB8 7UU, UK
    Vet Radiol Ultrasound 46:171-8. 2005
    ..The findings also suggest that distal tarsal RU in lame limbs is greater than in limbs without pain, and that painful limbs with radiographic evidence of OA have a greater RU than painful limbs without radiographic evidence of OA...
  26. ncbi High detail radiography and histology of the centrodistal tarsal joint of Icelandic horses age 6 months to 6 years
    S Bjornsdottir
    Hólar Agricultural College, IS 551 Saudárkrókur, Iceland
    Equine Vet J 36:5-11. 2004
    ..Osteoarthrosis (OA) in the distal tarsal joints, bone spavin, is a well known condition which is common in Icelandic horses age 6-12 years...
  27. ncbi Hindlimb adaptations in Ourayia and Chipetaia, relatively large-bodied omomyine primates from the Middle Eocene of Utah
    Rachel H Dunn
    Department of Anthropology, Washington University, St Louis, Missouri 63130, USA
    Am J Phys Anthropol 131:303-10. 2006
    ..The results of our comparisons suggest that the later, larger, more herbivorous omomyines from Utah retained a skeletal structure characteristic of earlier, smaller North American omomyids...
  28. ncbi Hock injury prevalence and associated risk factors on organic and nonorganic dairy farms in the United Kingdom
    K M D Rutherford
    Animal Behaviour and Welfare, Sustainable Livestock Systems, Scottish Agricultural College, West Mains Rd, Edinburgh, EH9 3JG, Scotland
    J Dairy Sci 91:2265-74. 2008
    ..Efforts are needed to improve housing standards to reduce the prevalence of hock injury and consequently improve cow welfare...
  29. ncbi Bovine claw and limb disorders related to reproductive performance and production diseases
    A M Sogstad
    Department of Production Animal Medicine, Norwegian School of Veterinary Science, 0033 Oslo, Norway
    J Dairy Sci 89:2519-28. 2006
    ..4). Our study shows that claw disorders are associated with poorer reproductive performance and some production diseases...
  30. ncbi Rupture of the plantar ligament in a goat
    S E Taylor
    Department of Veterinary Clinical Studies, Royal Dick School of Veterinary Studies, University of Edinburgh, Easter Bush Veterinary Centre, Roslin, Midlothian EH25 9RG
    Vet Rec 155:335-6. 2004
  31. ncbi Differences in stride between healthy ostriches (Struthio camelus) and those affected by tibiotarsal rotation
    R G Cooper
    Division of Physiology, UCE Birmingham, Baker Building, Room 701, Franchise Street, Perry Barr, Birmingham B42 2SU, UK
    J S Afr Vet Assoc 78:52-3. 2007
    ..05) reduced speeds. Hens may be able to escape danger faster than cocks. The occurrence of tibiotarsal rotation necessitates consideration of genetics, management, sex, nutrition and growth rates...
  32. ncbi Complications following tarsal arthrodesis using bone plate fixation in dogs
    S P Roch
    Willows Referral Service, 78 Tanworth Lane, Shirley, Soluhull b90 4DF, UK
    J Small Anim Pract 49:117-26. 2008
    ..To report the complications encountered following tarsal arthrodesis surgery with bone plate fixation and describe the previously unreported complication of plantar necrosis...
  33. ncbi Low frequency and low intensity pulsed electromagnetic field exerts its antiinflammatory effect through restoration of plasma membrane calcium ATPase activity
    Ramasamy Selvam
    Department of Pharmacology and Toxicology, Madras Veterinary College, Vepery, Chennai, India
    Life Sci 80:2403-10. 2007
    ..The results of this study indicated that PEMF could be developed as a potential therapy for RA in human beings...
  34. ncbi Osseous lesion of the calcaneus following the use of shock wave therapy in a horse
    N Diakakis
    Department of Clinical Studies, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, St Voutyra 11, 546 27 Thessaloniki, Greece
    J Vet Med A Physiol Pathol Clin Med 52:481-3. 2005
    ..On clinical re-evaluation 6 months after treatment, the degree of lameness was stable (1/10) and flexion test of the limb was negative...
  35. ncbi Arthrodesis of the tarsometatarsal joints in a cat with a two hole advanced locking plate system
    R Inauen
    Koch and Bass Referal Practice for Small Animal Surgery, Basadingerstrasse 26, 8253 Diessenhofen, Switzerland
    Vet Comp Orthop Traumatol 22:166-9. 2009
    ..Radiographs made after six weeks showed uneventful healing. ALPS offers an alternative to existing plating systems when selecting an implant for the stabilisation of dorsal tarsometatarsal instabilities in cats...
  36. ncbi Chip fractures from the distal lateral trochlear ridge of the talus of a quarter horse gelding: a veterinary medicine clinical report
    L Groves
    The Whole Horse, San Marcus, TX, USA
    Cell Mol Biol (Noisy-le-grand) 51:239-44. 2005
    ..The horse was treated initially with arthroscopic surgery. He was given a non-steroidal anti-inflammatory agent, and a chondroprotective agent to prevent further damage to, and aid in the healing of, the damaged joint...
  37. ncbi Small clades at the periphery of passerine morphological space
    Robert E Ricklefs
    Department of Biology, University of Missouri, St Louis, Missouri 63121 4499, USA
    Am Nat 165:651-9. 2005
    ....
  38. ncbi Prevalence of osseous fragments in distal and proximal interphalangeal, metacarpo- and metatarsophalangeal and tarsocrural joints of Hanoverian Warmblood horses
    K F Stock
    Institute of Animal Breeding and Genetics, University of Veterinary Medicine Hannover Foundation, Bunteweg 17p, D 30559 Hannover, Germany
    J Vet Med A Physiol Pathol Clin Med 52:388-94. 2005
    ..The results of this study indicate the need to act against the high prevalences of osseous fragments in the limb joints of young Warmblood riding horses...
  39. ncbi Ectopic cartilage formation of unknown origin in the plantar pouch of the tarsocrural joint in a yearling
    B Carstanjen
    Département hippique, Ecole Nationale Veterinaire de Lyon, 1 avenue Bourgelat, 69280 Marcy l Etoile, France
    Vet Rec 157:630-2. 2005
  40. pmc Sequential expression of type IV collagen networks: testis as a model and relevance to spermatogenesis
    Scott J Harvey
    Division of Pathology, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada
    Am J Pathol 168:1587-97. 2006
    ..This situation is analogous to the glomerular basement membrane in Alport syndrome. In conclusion, testis can serve as a model system to study the sequence of type IV collagen network expression...
  41. ncbi Prevalence of various presale radiographic findings and association of findings with sales price in Thoroughbred yearlings sold in Kentucky
    Stephanie A Preston
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610 0136, USA
    J Am Vet Med Assoc 236:440-5. 2010
    ....
  42. ncbi Extra domain B fibronectin as a target for near-infrared fluorescence imaging of rheumatoid arthritis affected joints in vivo
    Sonja Vollmer
    Bayer Schering Pharma, AG, Berlin, Germany
    Mol Imaging 8:330-40. 2009
    ..Given that AP39 is a fully human antibody fragment, this molecular imaging approach for arthritis detection might be translated to humans...
  43. pmc Kinematics of gait in golden retriever muscular dystrophy
    Anthony P Marsh
    Department of Health and Exercise Science, Wake Forest University, Winston Salem, NC 27109, USA
    Neuromuscul Disord 20:16-20. 2010
    ..This is the first kinematic study of gait in the GRMD dog, an important step in using this model in pre-clinical trials...
  44. ncbi Is there a relationship between clinical presentation, diagnostic and radiographic findings and outcome in horses with osteoarthritis of the small tarsal joints?
    K L Byam-Cook
    Division of Veterinary Clinical Studies, University of Liverpool, Leahurst, Neston, Cheshire CH64 7TE, UK
    Equine Vet J 41:118-23. 2009
    ....
  45. ncbi The candidate gene XIRP2 at a quantitative gene locus on equine chromosome 18 associated with osteochondrosis in fetlock and hock joints of South German Coldblood horses
    Catherine Wittwer
    Institute for Animal Breeding and Genetics, University of Veterinary Medicine Hannover, Foundation Bünteweg 17p, Hannover, Germany
    J Hered 100:481-6. 2009
    ..01-0.02) for hock OC. Homozygous (A/A or T/T) and heterozygous horses were at a 1.3- to 2.4-fold higher risk for fetlock and hock OC. These results suggest that dominant variants of XIRP2 may be involved in pathogenesis of equine OC...
  46. ncbi Different effects of spinally applied prostaglandin D2 on responses of dorsal horn neurons with knee input in normal rats and in rats with acute knee inflammation
    A Telleria-Diaz
    Department of Physiology I, Neurophysiology, Friedrich Schiller Universitat Jena, Teichgraben 8, D 07740 Jena, Germany
    Neuroscience 156:184-92. 2008
    ....
  47. ncbi Cartilage matrix changes in the developing epiphysis: early events on the pathway to equine osteochondrosis?
    M Lecocq
    Departement de Sciences Cliniques, Faculte de Medecine Veterinaire, Universite de Montreal, Quebec, Canada
    Equine Vet J 40:442-54. 2008
    ..The earliest osteochondrosis (OC) microscopic lesion reported in the literature was present in the femorotibial joint of a 2-day-old foal suggesting that OC lesions and factors initiating them may arise prior to birth...
  48. ncbi Multiple pathways to osteoarthritis and articular fractures: is subchondral bone the culprit?
    Antonio M Cruz
    Department of Clinical Studies, Comparative Orthopaedics Research Laboratory, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, Canada
    Vet Clin North Am Equine Pract 24:101-16. 2008
    ..Early recognition of these potentially career-ending diseases may require understanding of the progression of changes occurring in SCB with time and exercise...
  49. ncbi Physiological, morphological and behavioural effects of selecting zebra finches for divergent levels of corticosterone
    M L Roberts
    Centre for Ecology and Conservation, School of Biosciences, University of Exeter, Cornwall Campus, Penryn, Cornwall, UK
    J Exp Biol 210:4368-78. 2007
    ..Overall, our results suggest that the cell-mediated immune response is associated with a reduction in the humoral response, but only in males, and that there is no simple relationship between peak CORT levels and immune function...
  50. ncbi Diagnostic imaging of the equine tarsal region using radiography and ultrasonography. Part 1: the soft tissues
    Katrien Vanderperren
    Department of Medical Imaging, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Vet J 179:179-87. 2009
    ..In current clinical practice a combination of radiography and ultrasonography is still most frequently used to arrive at a diagnosis...
  51. ncbi Alteration of distal tarsal subchondral bone thickness pattern in horses with tarsal pain
    M V Branch
    Centre for Equine Studies, The Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk CB8 7UU, UK
    Equine Vet J 39:101-5. 2007
    ..Magnetic resonance imaging is often used in the analysis of human osteoarthritis (OA) because it is sensitive to early changes...
  52. ncbi Arthroscopic removal of fractures of the lateral malleolus of the tibia in the tarsocrural joint: a retrospective study of 13 cases
    H D O'Neill
    Donnington Grove Veterinary Surgery, Newbury, Berkshire, UK
    Equine Vet J 42:558-62. 2010
    ....
  53. pmc Protective effect of eotaxin-2 inhibition in adjuvant-induced arthritis
    J N Ablin
    Sourasky Medical Center, Rheumatology Institute, Tel Aviv University, Tel Aviv, Israel
    Clin Exp Immunol 161:276-83. 2010
    ..Inhibition of eotaxin-2 by monoclonal antibodies has a significant protective effect in adjuvant arthritis. These results may introduce a novel therapeutic target in rheumatoid arthritis and additional inflammatory joint disorders...
  54. ncbi Parasitism reduces the potential for evolution in a wild bird population
    Anne Charmantier
    Centre d Ecologie Fonctionnelle and Evolutive, Centre National de la Recherche Scientifique, 1919 Route de Mende, F 34293 Montpellier cedex 5, France
    Evolution 58:203-6. 2004
    ..To our knowledge, this experiment provides the first evidence of host quantitative genetics being influenced by parasitism, and illustrates the potential for parasitism to constrain an evolutionary response to selection...
  55. ncbi Dorsal tarsal instability in three racing greyhounds
    M J Guilliard
    Nantwich Veterinary Hospital, Crewe Road, Cheshire CW5 5SF
    J Small Anim Pract 44:415-7. 2003
    ..In these three cases, stability was restored by the insertion of a wire tension band anchored to two bone screws, allowing the development of periarticular fibrosis. The dogs raced again with no loss of form...
  56. ncbi Age-related changes in primary somatosensory cortex of rats: evidence for parallel degenerative and plastic-adaptive processes
    Ben Godde
    Institute of Medical Psychology and Behavioral Neurobiology, University of Tubingen, Gartenstr 29, 72074, Tubingen, Germany
    Neurosci Biobehav Rev 26:743-52. 2002
    ..We discuss the implications of these findings for cognitive functions at old age and possible treatments of age-related changes in human subjects...
  57. ncbi High-impact exercise and growing bone: relation between high strain rates and enhanced bone formation
    S Judex
    McCaig Centre for Joint Injury and Arthritis Research, University of Calgary, Alberta, Canada
    J Appl Physiol (1985) 88:2183-91. 2000
    ..Comparing the mechanical milieus produced by running and drop jumps revealed that jumping significantly elevated only peak strain rates. This further emphasized the sensitivity of immature bone to high strain rates...
  58. ncbi Osteosarcoma of the tarsus in a horse
    F Jenner
    Tufts University School of Veterinary Medicine, 200 Westborough Road, North Grafton, Massachusetts 01536, USA
    Equine Vet J 35:214-6. 2003
  59. ncbi The morphological basis of hallucal orientation in extant birds
    K M Middleton
    Department of Ecology and Evolutionary Biology, Brown University, Providence, Rhode Island 02912, USA
    J Morphol 250:51-60. 2001
    ..This method also avoids potential misinterpretations of hallucal orientation in fossil birds that could result from preserved appearance alone...
  60. ncbi Chronic intrathecal baclofen treatment and withdrawal: I. Changes in ankle torque and hind limb posture in normal rats
    David C Wang
    Department of Neuroscience, Evelyn F and William L McKnight Brain Institute, University of Florida, Gainesville, Florida 32610 0244, USA
    J Neurotrauma 19:875-86. 2002
    ..These studies were performed to provide a foundation for evaluation of treatment and withdrawal in the setting of experimental chronic contusion spinal cord injury...
  61. ncbi Radiographic changes in Thoroughbred yearlings. Part 2: Associations with racing performance
    A J Kane
    Equine Orthopaedic Research Laboratory, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado 80523, USA
    Equine Vet J 35:366-74. 2003
    ..Although the radiographic examination of yearlings has become commonplace at some large Thoroughbred sales, there are few data to support the decisions facing veterinarians who are asked to evaluate future racing potential...
  62. ncbi The effect of number of lengthening contractions on rat isometric force production at different frequencies of nerve stimulation
    M E T Willems
    Faculty of Sport, Exercise and Health Sciences, University of Chichester, Chichester, UK
    Acta Physiol (Oxf) 196:351-6. 2009
    ..To test the effect of 3, 10, 60 and 240 lengthening contractions (LC) on maximal isometric force of rat plantar flexor muscles at different stimulation frequencies...
  63. ncbi Adjuvant-induced joint inflammation causes very rapid transcription of beta-preprotachykinin and alpha-CGRP genes in innervating sensory ganglia
    D G Bulling
    Molecular Endocrinology, Molecular Medicine Centre, Western General Hospital, Edinburgh, UK
    J Neurochem 77:372-82. 2001
    ....
  64. ncbi Islet amyloid polypeptide and calcitonin gene-related peptide expression are upregulated in lumbar dorsal root ganglia after unilateral adjuvant-induced inflammation in the rat paw
    H Mulder
    Department of Physiology and Neuroscience, University of Lund, Lund University Hospital, Sweden
    Brain Res Mol Brain Res 50:127-35. 1997
    ..Thus, IAPP could play a role in the initial phase of localized inflammation...
  65. ncbi Activity-driven synaptic and axonal degeneration in canine motor neuron disease
    Dario I Carrasco
    Department of Physiology, Emory University School of Medicine, 615 Michael Street, Atlanta, GA 30322, USA
    J Neurophysiol 92:1175-81. 2004
    ..The results indicate that motor neuron action potential activity is a major contributing factor to the loss of motor-unit function and degeneration in inherited canine motor neuron disease...
  66. ncbi Osteoclast numbers in Lewis rats with adjuvant-induced arthritis: identification of preferred sites and parameters for rapid quantitative analysis
    B Bolon
    Department of Pathology, Amgen, Inc, Thousand Oaks, CA, USA
    Vet Pathol 41:30-6. 2004
    ..These data show that the navicular tarsal is the most sensitive site at which to assess arthritis in rats with this variant of adjuvant-induced arthritis...
  67. ncbi [Navicular disease in the hind limb of a Warmblood horse]
    M C Meijer
    Hoofdafdeling Gezondheidszorg Paard, Faculteit der Diergeneeskunde, Universiteit Utrecht
    Tijdschr Diergeneeskd 124:536-8. 1999
    ..The therapy was repeated following recurrence of the lameness. According to the owner the horse is currently performing at its previous level...
  68. ncbi Gender and viability selection on morphology in fledgling pied flycatchers
    J Potti
    Departamento de Biologia Animal, Facultad de Biologia, Universidad de Alcala, E 28871 Alcala de Henares, Madrid, Spain
    Mol Ecol 11:1317-26. 2002
    ..Overall, selection on fledgling viability on the basis of morphological traits and hatching date was not confounded by an individual's gender...
  69. ncbi Force output during and following active stretches of rat plantar flexor muscles: effect of velocity of ankle rotation
    M E Willems
    Department of Physiology, West Virginia University, Morgantown, WV 26506, USA
    J Biomech 33:1035-8. 2000
    ..The change in time constant of force decay during stress relaxation in response to a series of repeated stretches might provide information on the sarcomere length distribution in skeletal muscles...
  70. ncbi Preliminary study of joint disease in poultry by the analysis of synovial fluid
    S A Corr
    Division of Small Animal Clinical Studies, University of Glasgow Veterinary School, Bearsden Road, Glasgow G61 1QH
    Vet Rec 152:549-54. 2003
    ..The birds fed ad libitum which were treated with carprofen had more cells in the synovial fluid than the birds given the placebo. A large number of the samples of synovial fluid from the ad libitum-fed broilers contained blood...
  71. ncbi Sensory and vascular changes in a rat monoarthritis model: prophylactic and therapeutic effects of meloxicam
    Javeria Ali Hashmi
    Department of Physiology and Pharmacology, University of Western Ontario, London, ON, Canada
    Inflamm Res 59:667-78. 2010
    ..The objective of this study was to determine the ability of meloxicam prophylaxis and therapy to blunt the effect of complete Freund's adjuvant (CFA) induced monoarthritis...
  72. ncbi Testing the phenotypic gambit: phenotypic, genetic and environmental correlations of colour
    J D Hadfield
    Division of Biology, Imperial College London, Ascot, Berkshire, UK
    J Evol Biol 20:549-57. 2007
    ..For this group of traits, the phenotypic gambit cannot be made and we suggest caution when inferring genetic patterns from phenotypic data, especially for behavioural and life-history traits...
  73. ncbi Analysis of avian bone response to mechanical loading-Part one: Distribution of bone fluid shear stress induced by bending and axial loading
    Li Y Mi
    New York Center for Biomedical Engineering, Department of Electrical Engineering, The City College of New York CUNY, New York, NY 10031, USA
    Biomech Model Mechanobiol 4:118-31. 2005
    ..These results suggest that the radial strain gradient is the driving force for bone fluid flow in the radially distributed lacunar-canalicular system and that bone formation is not linearly related to the loading-induced local stimulus...
  74. ncbi Are kinematics of the walk related to the locomotion of a warmblood horse at the trot?
    W Back
    Department of General and Large Animal Surgery, Faculty of Veterinary Medicine, Utrecht University, The Netherlands
    Vet Q 18:S79-84. 1996
    ..In conclusion, kinematics recorded at the walk in a group of horses were similar to and thus predictive for locomotion at the trot providing the decreased stance duration and the increased speed of the trot are taken into consideration...
  75. ncbi Identified ankle extensor and flexor motoneurons display different firing profiles in the neonatal rat
    Florence Cotel
    Laboratoire de Neurobiologie des Signaux Intercellulaires, Centre National de la Recherche Scientifique Unité Mixte de Recherche CNRS UMR 7101, Universite Pierre et Marie Curie Paris 6, F 75252 Paris Cedex 05, France
    J Neurosci 29:2748-53. 2009
    ..Thus, during the early postnatal development, a significant part of the population of extensor motoneurons, but not flexors, are able to produce self-sustained discharges known to involve the activation of persistent inward currents...
  76. ncbi Sex-based comparison of limb segmentation in ostriches aged 14 months with and without tibiotarsal rotation
    R G Cooper
    Division of Physiology, City North Campus, Birmingham City University, 704 Baker Building, Franchise Street, Perry Barr, Birmingham B42 2SU, UK
    J S Afr Vet Assoc 79:142-4. 2008
    ..Birds suffering from TTR may experience an increased degree of stress due to movement restrictions in confinement...
  77. ncbi [Ultrasonographic findings of disorders of the tarsal region in 97 cattle--arthritis, bursitis, tenosynovitis, periarticular abscess and vein thrombosis]
    Johann Kofler
    Klinisches Department für Kleintiere und Pferde, Klinik für Orthopädie bei Huf und Klauentieren, Veterinärmedizinische Universität Wien, Wien, Osterreich
    Berl Munch Tierarztl Wochenschr 121:145-58. 2008
    ....
  78. ncbi Repair of a coracoid luxation and a tibiotarsal fracture in a bald eagle (Haliaeetus leucocephalus)
    David Sanchez Migallon Guzman
    Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803 8410, USA
    J Avian Med Surg 21:188-95. 2007
    ..7-mm DCP. The bird was successfully released, 105 days after the first surgery, near the location where it was found...
  79. pmc Functional role of muscle reflexes for force generation in the decerebrate walking cat
    R B Stein
    Department of Physiology and Division of Neuroscience, University of Alberta, Edmonton, AB, Canada T6G
    J Physiol 525:781-91. 2000
    ....
  80. ncbi Asymmetric adaptive modeling of central tarsal bones in racing greyhounds
    K A Johnson
    Department of Veterinary Clinical Sciences, The Ohio State University, Columbus, OH 43210 1089, USA
    Bone 27:257-63. 2000
    ..Racing greyhounds provide a model in which to study fatigue fracture and adaptation of cuboidal foot bones subjected to cyclic loading...
  81. ncbi Superficial digital flexor tendon lesions in racehorses as a sequela to muscle fatigue: a preliminary study
    M T Butcher
    Department of Biological Sciences, 132 Long Hall, Clemson University, Clemson, South Carolina 29634, USA
    Equine Vet J 39:540-5. 2007
    ..Racing and training related lesions of the forelimb superficial digital flexor tendon are a common career ending injury to racehorses but aetiology and/or predisposing causes of the injury are not completely understood...
  82. ncbi Intra-articular pressure profiles of the cadaveric equine fetlock joint in motion
    D da Gracca Macoris
    Department of Veterinary Clinic Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, USA
    Equine Vet J 33:184-90. 2001
    ..5. Additional in vivo studies are necessary to confirm our conclusions from this study and to identify the contributions of fluid absorption and the presence of ischaemia in a vascularised joint...
  83. ncbi Diagnostic imaging of the equine tarsal region using radiography and ultrasonography. Part 2: bony disorders
    Katrien Vanderperren
    Department of Medical Imaging, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Vet J 179:188-96. 2009
    ..The diagnostic use of arthroscopy, computed tomography and magnetic resonance are discussed. In current clinical practice the most frequently used combination to arrive at a diagnosis is still radiography and ultrasonography...
  84. ncbi Does the mechanical milieu associated with high-speed running lead to adaptive changes in diaphyseal growing bone?
    S Judex
    McCaig Centre for Joint Injury and Arthritis Research, University of Calgary, AB, Canada
    Bone 26:153-9. 2000
    ..This study also supports the tenet that the exercise-generated mechanical milieu must differ substantially from the habitual milieu to induce significant adaptations...
  85. ncbi An experimental study on the effects of polymorphiasis in common eider ducklings
    T Hollmen
    Faculty of Veterinary Medicine, Department of Basic Veterinary Sciences, University of Helsinki, Finland
    J Wildl Dis 35:466-73. 1999
    ..The parasites were attached to the mucosa of the posterior small intestine of the infected ducklings with a mixed inflammatory reaction consisting of heterophils and mononuclear lymphocytes surrounding the attachment sites...
  86. ncbi A novel, nonsurgical method for the treatment of tibiotarsal rotation in houbara bustard (Chlamydotis macqueenii) chicks
    Corinne Stiévenart
    National Wildlife Research Center, PO Box 1086, Taif, Saudi Arabia
    J Avian Med Surg 22:25-30. 2008
    ..Implementing the same corrective method at an older age was not successful. This cheap, accessible, and noninvasive technique may be applicable to other avian species...
  87. ncbi Force-sharing among the primary cat ankle muscles
    W Herzog
    University of Calgary, Faculty of Kinesiology, AB, Canada
    Eur J Morphol 36:280-7. 1998
    ....
  88. ncbi Horseradish peroxidase study of the spatial and electrotonic distribution of group Ia synapses on type-identified ankle extensor motoneurons in the cat
    R E Burke
    Laboratory of Neural Control, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20814 4455, USA
    J Comp Neurol 372:465-85. 1996
    ..The relations between these anatomical results and existing electrophysiological data on group Ia synaptic potentials are discussed...
  89. ncbi In vitro and in vivo evaluation of ferric-hyaluronate implants for delivery of amikacin sulfate to the tarsocrural joint of horses
    Nicola C Cribb
    Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada
    Vet Surg 38:498-505. 2009
    ..To assess the antimicrobial elution characteristics, toxicity, and antimicrobial activity of amikacin-impregnated ferric-hyaluronate implants (AI-FeHAI) for amikacin delivery to the tarsocrural joint of horses...
  90. ncbi Morphology and neurophysiology of tarsal vibration receptors in the water strider Aquarius paludum (Heteroptera: Gerridae)
    Pablo Perez Goodwyn
    Laboratory of Insect Ecology, Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University, 606 8502, Kyoto, Japan
    J Insect Physiol 55:855-61. 2009
    ..In turn, four ventral subapical trichobothria that are in direct contact with the water surface during locomotion, proved to be mechanosensory. The anatomical and ultrastructural observations support these electro-physiological results...
  91. pmc Control of distal antennal identity and tarsal development in Drosophila by spineless-aristapedia, a homolog of the mammalian dioxin receptor
    D M Duncan
    Department of Biology, Washington University, St Louis, Missouri 63130, USA
    Genes Dev 12:1290-303. 1998
    ..The antennal transformation and tarsal deletions caused by ss loss-of-function mutations are probably atavistic, suggesting that ss played a central role in the evolution of distal structures in arthropod limbs...
  92. ncbi Use of a petroleum-based bolus for photon radiation therapy of distal extremities in dogs
    Monique N Mayer
    Radiation Products Design, Albertville, MN, USA
    Vet Radiol Ultrasound 50:235-8. 2009
    ..This petroleum-based bolus is equivalent to water in its photon attenuation, conforms well to an irregular patient contour, and retains its shape after positioning. Applications to other anatomical sites could be considered...
  93. pmc Analysis in Drosophila melanogaster of the interaction between sex combs reduced and extradenticle activity in the determination of tarsus and arista identity
    A Percival-Smith
    Department of Zoology, University of Western Ontario, London, Ontario N6A 5B7, Canada
    Genetics 150:189-98. 1998
    ....
  94. ncbi Relationship between hind limb lameness and radiographic signs of bone spavin in Icelandic horses in Sweden
    M Axelsson
    Department of Large Animal Clinical Sciences, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, Uppsala, Sweden
    Acta Vet Scand 39:349-57. 1998
    ..Using palpation, motion evaluation, and flexion test 75% of the horses with RSBS were identified. The rate of agreement between the clinical examination and the radiographic examination was 73%...
  95. ncbi Immobilization-induced cartilage degeneration mediated through expression of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and chondromodulin-I
    Junya Sakamoto
    Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Connect Tissue Res 50:37-45. 2009
    ..Our results showed that immobilization induces thinning of the articular cartilage and appearance of vascular channel, in areas with balanced expression of HIF-1alpha/VEGF and ChM-1...
  96. ncbi Nonrigid external fixation of the elbow, coxofemoral, and tarsal joints in dogs
    Zeev Schwartz
    The University of Illinois, IL, USA
    Compend Contin Educ Vet 30:648-53. 2008
    ..This article describes simple, cost effective techniques for the percutaneous application of external fixators to the elbow, coxofemoral, and tarsal joint of dogs...
  97. ncbi Virtual histology by means of high-resolution X-ray CT
    V Cnudde
    Department of Geology and Soil Science, Ghent University, Krijgslaan 281 S8, B 9000, Ghent, Belgium
    J Microsc 232:476-85. 2008
    ..ugct.ugent.be). This state-of-the-art set-up provides a 1 micron resolution and is therefore ideally suited for a direct comparison with standard light microscopy-based histology...
  98. ncbi Effects of a digital filter on detectability of a phantom lesion in a scintigram of the equine tarsus
    P Eksell
    Department of Clinical Radiology, Swedish University of Agricultural Sciences, Uppsala
    Vet Radiol Ultrasound 41:365-70. 2000
    ..Based on receiver operating characteristic analysis, filtering of a 50 kcount image improved image quality to that of a 150 kcount image...
  99. ncbi Eggshell pigmentation pattern in relation to breeding performance of blue tits Cyanistes caeruleus
    Juan Jose Sanz
    Departamento de Ecologia Evolutiva, Museo Nacional de Ciencias Naturales CSIC, José Gutiérrez Abascal, 2 E 28006 Madrid, Spain
    J Anim Ecol 78:31-41. 2009
    ..Further investigations are needed to understand the role of calcium availability as possible causal agent of deviant eggs and its relation to the maculation phenomenon...
  100. ncbi Effects of dorsolateral spinal lesions on stretch reflex threshold and stiffness in awake cats
    J Taylor
    Department of Neuroscience, University of Florida, Gainesville 32610, USA
    Eur J Neurosci 11:363-8. 1999
    ..These and related observations suggest that the postoperative increase in IDS in awake animals was not due to an increase in passive stiffness...
  101. ncbi Integration within and between muscles during terrestrial locomotion: effects of incline and speed
    Timothy E Higham
    Department of Organismic and Evolutionary Biology, Concord Field Station, Harvard University, 100 Old Causeway Road, Bedford, MA 01730, USA
    J Exp Biol 211:2303-16. 2008
    ..Our results demonstrate the capacity for functional diversity between and within muscle synergists, which occur with changes in gait, speed and grade...

Research Grants1

  1. Modulation of Bone's Mechanical Behavior by Bone Quality
    Stefan Judex; Fiscal Year: 2010
    ..Identification of these potential chemical targets will provide critical information for improved diagnostic, prophylactic, and therapeutic means of addressing bone quality defects in disease. ..