Summary: Macroporous hydrogels that are produced at subzero temperatures. Cryogels have pores that are produced by growing ice crystals and have been developed with a tissue-like elasticity that is suitable for cell immunization experiments.
- Aydin D, Arslan M, Sanyal A, Sanyal R. Hooked on Cryogels: A Carbamate Linker Based Depot for Slow Drug Release. Bioconjug Chem. 2017;28:1443-1451 pubmed publisherPoly(ethylene glycol) (PEG) based bulk hydrogels and cryogels containing activated carbonate groups as amine reactive handles to facilitate drug conjugations through carbamate linkages were fabricated and evaluated as slow releasing drug ..
- Ghaderi Gandomani M, Sahebghadam Lotfi A, Kordi tamandani D, Arjmand S, Alizadeh S. The enhancement of differentiating adipose derived mesenchymal stem cells toward hepatocyte like cells using gelatin cryogel scaffold. Biochem Biophys Res Commun. 2017;491:1000-1006 pubmed publisher..Finally, the created 3D gelatin scaffold could provide an appropriate matrix for hepatogenic differentiation of hADSCs, which could be considered for liver tissue engineering applications. ..