european continental ancestry group

Summary

Summary: Individuals whose ancestral origins are in the continent of Europe.

Top Publications

  1. ncbi High-density SNP genotyping detects homogeneity of Spanish and French Basques, and confirms their genomic distinctiveness from other European populations
    Naiara Rodriguez-Ezpeleta
    Genome Analysis Platform, Functional Genomics Unit, CIC bioGUNE, Bizkaia Technology Park, Building 502, 48160, Derio, Spain
    Hum Genet 128:113-7. 2010
  2. pmc Biological, clinical and population relevance of 95 loci for blood lipids
    Tanya M Teslovich
    Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA
    Nature 466:707-13. 2010
  3. ncbi The structure of haplotype blocks in the human genome
    Stacey B Gabriel
    Whitehead MIT Center for Genome Research, Cambridge, MA 02139, USA
    Science 296:2225-9. 2002
  4. pmc Genome-wide association study identifies eight loci associated with blood pressure
    Christopher Newton-Cheh
    Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA
    Nat Genet 41:666-76. 2009
  5. doi Genetics of gene expression and its effect on disease
    Valur Emilsson
    deCODE Genetics, 101 Reykjavik, Iceland
    Nature 452:423-8. 2008
  6. pmc Assessing the evolutionary impact of amino acid mutations in the human genome
    Adam R Boyko
    Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, USA
    PLoS Genet 4:e1000083. 2008
  7. ncbi Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey
    Earl S Ford
    Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Mailstop E 17, Atlanta, GA 30333
    JAMA 287:356-9. 2002
  8. pmc The history of African gene flow into Southern Europeans, Levantines, and Jews
    Priya Moorjani
    Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS Genet 7:e1001373. 2011
  9. pmc Demographic differences and trends of vitamin D insufficiency in the US population, 1988-2004
    Adit A Ginde
    Department of Emergency Medicine, University of Colorado Denver School of Medicine, Aurora, 80045, USA
    Arch Intern Med 169:626-32. 2009
  10. ncbi Sequence variations in PCSK9, low LDL, and protection against coronary heart disease
    Jonathan C Cohen
    Donald W Reynolds Cardiovascular Clinical Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390 9046, USA
    N Engl J Med 354:1264-72. 2006

Detail Information

Publications251 found, 100 shown here

  1. ncbi High-density SNP genotyping detects homogeneity of Spanish and French Basques, and confirms their genomic distinctiveness from other European populations
    Naiara Rodriguez-Ezpeleta
    Genome Analysis Platform, Functional Genomics Unit, CIC bioGUNE, Bizkaia Technology Park, Building 502, 48160, Derio, Spain
    Hum Genet 128:113-7. 2010
    ..Here, we present the first high-throughput analysis including Basques from Spanish and French provinces, and show that all Basques constitute a homogeneous group that can be clearly differentiated from other European populations...
  2. pmc Biological, clinical and population relevance of 95 loci for blood lipids
    Tanya M Teslovich
    Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA
    Nature 466:707-13. 2010
    ..Taken together, our findings provide the foundation to develop a broader biological understanding of lipoprotein metabolism and to identify new therapeutic opportunities for the prevention of CAD...
  3. ncbi The structure of haplotype blocks in the human genome
    Stacey B Gabriel
    Whitehead MIT Center for Genome Research, Cambridge, MA 02139, USA
    Science 296:2225-9. 2002
    ..Our results provide a foundation for the construction of a haplotype map of the human genome, facilitating comprehensive genetic association studies of human disease...
  4. pmc Genome-wide association study identifies eight loci associated with blood pressure
    Christopher Newton-Cheh
    Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA
    Nat Genet 41:666-76. 2009
    ..These associations between common variants and blood pressure and hypertension offer mechanistic insights into the regulation of blood pressure and may point to novel targets for interventions to prevent cardiovascular disease...
  5. doi Genetics of gene expression and its effect on disease
    Valur Emilsson
    deCODE Genetics, 101 Reykjavik, Iceland
    Nature 452:423-8. 2008
    ..A core network module in humans and mice was identified that is enriched for genes involved in the inflammatory and immune response and has been found to be causally associated to obesity-related traits...
  6. pmc Assessing the evolutionary impact of amino acid mutations in the human genome
    Adam R Boyko
    Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, USA
    PLoS Genet 4:e1000083. 2008
    ....
  7. ncbi Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey
    Earl S Ford
    Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Mailstop E 17, Atlanta, GA 30333
    JAMA 287:356-9. 2002
    ..Limited information is available about the prevalence of the metabolic syndrome in the United States, however...
  8. pmc The history of African gene flow into Southern Europeans, Levantines, and Jews
    Priya Moorjani
    Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS Genet 7:e1001373. 2011
    ..For the Jewish admixture, we obtain an average estimated date of about 72 generations. This may reflect descent of these groups from a common ancestral population that already had some African ancestry prior to the Jewish Diasporas...
  9. pmc Demographic differences and trends of vitamin D insufficiency in the US population, 1988-2004
    Adit A Ginde
    Department of Emergency Medicine, University of Colorado Denver School of Medicine, Aurora, 80045, USA
    Arch Intern Med 169:626-32. 2009
    ..Vitamin D insufficiency is associated with suboptimal health. The prevalence of vitamin D insufficiency may be rising, but population-based trends are uncertain. We sought to evaluate US population trends in vitamin D insufficiency...
  10. ncbi Sequence variations in PCSK9, low LDL, and protection against coronary heart disease
    Jonathan C Cohen
    Donald W Reynolds Cardiovascular Clinical Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390 9046, USA
    N Engl J Med 354:1264-72. 2006
    ..We examined the effect of DNA-sequence variations that reduce plasma levels of LDL cholesterol on the incidence of coronary events in a large population...
  11. pmc Ancestry informative marker sets for determining continental origin and admixture proportions in common populations in America
    Roman Kosoy
    Rowe Program in Human Genetics, Department of Biochemistry, University of California Davis, Davis, California 95616, USA
    Hum Mutat 30:69-78. 2009
    ..We conclude that investigators can use TaqMan assays for the selected AIMs as a simple and cost efficient tool to control for differences in continental ancestry when conducting association studies in ethnically diverse populations...
  12. pmc Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer
    M D Ritchie
    Program in Human Genetics, Department of Molecular Physiology and Biophysics, Vanderbilt University Medical School, Nashville, TN 37232, USA
    Am J Hum Genet 69:138-47. 2001
    ..To our knowledge, this is the first report of a four-locus interaction associated with a common complex multifactorial disease...
  13. pmc Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
    Yurii S Aulchenko
    1 Department of Epidemiology and Biostatistics, Erasmus University Medical Center, P O Box 2040, 3000 CA Rotterdam, The Netherlands 2 These authors contributed equally to this work
    Nat Genet 41:47-55. 2009
    ..001) and coronary heart disease incidence (P = 0.04). The genetic risk score improves the screening of high-risk groups of dyslipidemia over classical risk factors...
  14. pmc Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways
    Nicole Soranzo
    Human Genetics, Wellcome Trust Sanger Institute, Hinxton, U K
    Diabetes 59:3229-39. 2010
    ..We aimed to identify such genetic factors and investigate the extent to which they influence diabetes classification based on HbA₁(c) levels...
  15. ncbi Asians are different from Caucasians and from each other in their body mass index/body fat per cent relationship
    P Deurenberg
    Wageningen University, The Netherlands
    Obes Rev 3:141-6. 2002
    ..Hence, the relationship between BF% and BMI is ethnic-specific. For comparisons of obesity prevalence between ethnic groups, universal BMI cut-off points are not appropriate...
  16. doi Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia
    Johan Rung
    McGill University and Genome Quebec Innovation Centre, Montreal, Canada
    Nat Genet 41:1110-5. 2009
    ....
  17. pmc The landscape of recombination in African Americans
    Anjali G Hinch
    Wellcome Trust Centre for Human Genetics, Oxford University, Roosevelt Drive, Oxford OX3 7BN, UK
    Nature 476:170-5. 2011
    ..Sites of this motif are predicted to be risk loci for disease-causing genomic rearrangements in individuals carrying these alleles. More generally, this map provides a resource for research in human genetic variation and evolution...
  18. pmc FTO, type 2 diabetes, and weight gain throughout adult life: a meta-analysis of 41,504 subjects from the Scandinavian HUNT, MDC, and MPP studies
    Jens K Hertel
    Department of Clinical Medicine, University of Bergen, Bergen, Norway
    Diabetes 60:1637-44. 2011
    ..FTO is the most important polygene identified for obesity. We aimed to investigate whether a variant in FTO affects type 2 diabetes risk entirely through its effect on BMI and how FTO influences BMI across adult life span...
  19. pmc Epidemiology of basal-like breast cancer
    Robert C Millikan
    Department of Epidemiology, CB 7435, School of Public Health, University of North Carolina, Chapel Hill, NC 27599 7435, USA
    Breast Cancer Res Treat 109:123-39. 2008
    ..Among younger African-American women, we estimate that up to 68% of basal-like breast cancer could be prevented by promoting breastfeeding and reducing abdominal adiposity...
  20. pmc Runs of homozygosity in European populations
    Ruth McQuillan
    Public Health Sciences, University of Edinburgh Medical School, Edinburgh EH8 9AG, UK
    Am J Hum Genet 83:359-72. 2008
    ....
  21. doi Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus
    Kazuki Yasuda
    Department of Metabolic Disorder, Research Institute, International Medical Center of Japan, Tokyo 162 8655, Japan
    Nat Genet 40:1092-7. 2008
    ..Our data thus implicate KCNQ1 as a diabetes susceptibility gene in groups of different ancestries...
  22. ncbi Waist circumference percentiles in nationally representative samples of African-American, European-American, and Mexican-American children and adolescents
    Jose R Fernandez
    Section on Statistical Genetics, Department of Biostatistics, Clinical Nutrition Research Center, University of Alabama at Birmingham, 35294 3360, USA
    J Pediatr 145:439-44. 2004
    ..To describe and provide estimates of the distribution of waist circumference (WC) according to percentiles in African-, European-, and Mexican-American children, and to test for group differences at different percentiles...
  23. pmc Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability
    Serena Sanna
    Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche CNR, Monserrato, Italy
    PLoS Genet 7:e1002198. 2011
    ..Further, our results suggest that, as prelude to large-scale sequencing efforts, targeted re-sequencing efforts paired with large-scale genotyping will increase estimates of complex trait heritability explained by known loci...
  24. pmc Genetic structure of Europeans: a view from the North-East
    Mari Nelis
    Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia
    PLoS ONE 4:e5472. 2009
    ..Together with previously published data, our results allow the creation of a comprehensive European genetic map that will greatly facilitate inter-population genetic studies including genome wide association studies (GWAS)...
  25. doi Cumulative effects and predictive value of common obesity-susceptibility variants identified by genome-wide association studies
    Shengxu Li
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK
    Am J Clin Nutr 91:184-90. 2010
    ..Large-scale genome-wide association studies have identified 12 genetic loci that are robustly associated with body mass index (BMI)...
  26. doi Inferring ancestral origin using a single multiplex assay of ancestry-informative marker SNPs
    C Phillips
    Forensic Genetics Department, University of Santiago de Compostela, 15782, and Centro Nacional de Genotipado CeGen, Hospital Clinico Universitario, 15706 Galicia, Spain
    Forensic Sci Int Genet 1:273-80. 2007
    ..This study shows that by choosing SNPs exhibiting marked allele frequency differences between population-groups a practical forensic test for assigning the most likely ancestry can be achieved from a single multiplexed assay...
  27. doi A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci
    Yukinori Okada
    Center for Genomic Medicine, Institute of Physical and Chemical Research, RIKEN, Kanagawa, Japan
    Hum Mol Genet 19:2303-12. 2010
    ..26 cm (95% confidence interval: 1.18-1.34) per 1.0 increase of the normalized Z score for height-increasing alleles, explaining 4.6% of the total variance of adult height...
  28. pmc Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals
    Zari Dastani
    Department of Epidemiology, Biostatistics, and Occupational Health, Jewish General Hospital, Lady Davis Institute, McGill University, Montreal, Canada
    PLoS Genet 8:e1002607. 2012
    ..4×10(-4), n = 121,335). These findings identify novel genetic determinants of adiponectin levels, which, taken together, influence risk of T2D and markers of insulin resistance...
  29. doi SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations
    Hiroyuki Unoki
    Laboratory for Endocrinology and Metabolism, Center for Genomic Medicine, RIKEN, Yokohama, Kanagawa 230 0045, Japan
    Nat Genet 40:1098-102. 2008
    ..5 x 10(-3); OR = 1.14, rs2237897, P = 2.4 x 10(-4); OR = 1.22) and Danish populations (additive model: rs2237895, P = 3.7 x 10(-11); OR = 1.24, rs2237897, P = 1.2 x 10(-4); OR = 1.36)...
  30. pmc An ancestry informative marker set for determining continental origin: validation and extension using human genome diversity panels
    Rami Nassir
    Rowe Program in Human Genetics, Departments of Biochemistry and Medicine, University of California Davis, Davis, CA 95616, USA
    BMC Genet 10:39. 2009
    ..Previously, we described a panel of 128 SNP AIMs that were designed as a tool for ascertaining the origins of subjects from Europe, Sub-Saharan Africa, Americas, and East Asia...
  31. doi Tumor immunobiological differences in prostate cancer between African-American and European-American men
    Tiffany A Wallace
    Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892 4258, USA
    Cancer Res 68:927-36. 2008
    ..The profiles portray the existence of a distinct tumor microenvironment in these two patient groups...
  32. pmc A predominantly neolithic origin for European paternal lineages
    Patricia Balaresque
    Department of Genetics, University of Leicester, Leicester, United Kingdom
    PLoS Biol 8:e1000285. 2010
    ....
  33. ncbi Differences in breast carcinoma characteristics in newly diagnosed African-American and Caucasian patients: a single-institution compilation compared with the National Cancer Institute's Surveillance, Epidemiology, and End Results database
    Gloria J Morris
    Department of Medical Oncology, Kimmel Cancer Center, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA
    Cancer 110:876-84. 2007
    ..Breast carcinomas in African-American patients appear to be more aggressive than in Caucasian patients due to multifactorial differences...
  34. ncbi State of disparities in cardiovascular health in the United States
    George A Mensah
    Office of the Director, Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control, Mail Stop K 40, 4770 Buford Hwy NE, Atlanta, GA 30341 3717, USA
    Circulation 111:1233-41. 2005
    ..Having timely access to current data on disparities is important for policy and program development. Accordingly, we assessed the current magnitude of disparities in cardiovascular disease (CVD) and its risk factors in the United States...
  35. pmc Adiposity, cardiometabolic risk, and vitamin D status: the Framingham Heart Study
    Susan Cheng
    Framingham Heart Study, Framingham, Massachusetts, USA
    Diabetes 59:242-8. 2010
    ..Few studies relating vitamin D deficiency to obesity have included direct measures of adiposity. Furthermore, the degree to which vitamin D is associated with metabolic traits after adjusting for adiposity measures is unclear...
  36. ncbi Variants conferring risk of atrial fibrillation on chromosome 4q25
    Daniel F Gudbjartsson
    deCODE Genetics, Sturlugata 8, 101 Reykjavik, Iceland
    Nature 448:353-7. 2007
    ..42 per copy. A stronger association was observed in individuals with typical atrial flutter. Both variants are adjacent to PITX2, which is known to have a critical function in left-right asymmetry of the heart...
  37. pmc CUBN is a gene locus for albuminuria
    Carsten A Böger
    Department of Internal Medicine II, University Medical Center Regensburg, Regensburg, Germany
    J Am Soc Nephrol 22:555-70. 2011
    ..In summary, we identified a missense CUBN variant that associates with levels of albuminuria in both the general population and in individuals with diabetes...
  38. pmc Identification of a new prostate cancer susceptibility locus on chromosome 8q24
    Meredith Yeager
    Core Genotyping Facility, SAIC Frederick, Inc, NCI Frederick, Frederick, Maryland, USA
    Nat Genet 41:1055-7. 2009
    ..3 x 10(-10), heterozygote OR = 1.17, 95% CI 1.10-1.24; homozygote OR = 1.33, 95% CI 1.21-1.45). This defines a new locus associated with prostate cancer susceptibility on 8q24...
  39. pmc Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways
    Lisette Stolk
    Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
    Nat Genet 44:260-8. 2012
    ..Gene-set enrichment pathway analyses using the full GWAS data set identified exoDNase, NF-κB signaling and mitochondrial dysfunction as biological processes related to timing of menopause...
  40. ncbi Race and gender differences in C-reactive protein levels
    Amit Khera
    Donald W Reynolds Cardiovascular Clinical Research Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9047, USA
    J Am Coll Cardiol 46:464-9. 2005
    ..This study sought to determine whether there are race and gender differences in the distribution of C-reactive protein (CRP) levels...
  41. doi Will all Americans become overweight or obese? estimating the progression and cost of the US obesity epidemic
    Youfa Wang
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    Obesity (Silver Spring) 16:2323-30. 2008
    ..Timely, dramatic, and effective development and implementation of corrective programs/policies are needed to avoid the otherwise inevitable health and societal consequences implied by our projections ...
  42. ncbi Hypovitaminosis D prevalence and determinants among African American and white women of reproductive age: third National Health and Nutrition Examination Survey, 1988-1994
    Shanna Nesby-O'Dell
    Division of Nutrition and Physical Activity, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta 30341 3717, USA
    Am J Clin Nutr 76:187-92. 2002
    ..African American women are at higher risk of vitamin D deficiency than are white women, but few studies have examined determinants of hypovitaminosis D in this population...
  43. doi No significant association of 14 candidate genes with schizophrenia in a large European ancestry sample: implications for psychiatric genetics
    Alan R Sanders
    Department of Psychiatry and Behavioural Sciences, Evanston Northwestern Healthcare Research Institute, Evanston, IL 60201 3137, USA
    Am J Psychiatry 165:497-506. 2008
    ....
  44. pmc Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene
    Manfred Kayser
    Department of Forensic Molecular Biology, Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands
    Am J Hum Genet 82:411-23. 2008
    ..Testing markers in the HERC2-OCA2 region may be useful in forensic applications to predict eye color phenotypes of unknown persons of European genetic origin...
  45. ncbi Visceral adipose tissue accumulation differs according to ethnic background: results of the Multicultural Community Health Assessment Trial (M-CHAT)
    Scott A Lear
    School of Kinesiology, Simon Fraser University, Vancouver, BC, Canada
    Am J Clin Nutr 86:353-9. 2007
    ..Previous studies have not adequately investigated differences in discrete regions of abdominal adiposity across ethnic groups...
  46. pmc A genome-wide association study of serum uric acid in African Americans
    Bashira A Charles
    Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD 20892, USA
    BMC Med Genomics 4:17. 2011
    ....
  47. pmc Reproductive history and oral contraceptive use in relation to risk of triple-negative breast cancer
    Amanda I Phipps
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    J Natl Cancer Inst 103:470-7. 2011
    ..Hormonally mediated risk factors may be differentially related to risk of triple-negative and ER+ breast cancers...
  48. pmc Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption
    Gunter Schumann
    Medical Research Council Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College, London SE5 8AF, United Kingdom
    Proc Natl Acad Sci U S A 108:7119-24. 2011
    ..001). Our finding of a regulator of alcohol consumption adds knowledge to our understanding of genetic mechanisms influencing alcohol drinking behavior...
  49. pmc The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans
    Nancy L Saccone
    Department of Genetics, Washington University, St Louis, Missouri 63110, UA
    Cancer Res 69:6848-56. 2009
    ..The nonsynonymous SNP rs16969968, a known risk variant in populations of European-descent, is also significantly associated with risk in African-Americans. Additional SNPs contribute to risk in distinct ways in these two populations...
  50. pmc A major Y-chromosome haplogroup R1b Holocene era founder effect in Central and Western Europe
    Natalie M Myres
    Sorenson Molecular Genealogy Foundation, Salt Lake City, UT, USA
    Eur J Hum Genet 19:95-101. 2011
    ....
  51. doi Race and triple negative threats to breast cancer survival: a population-based study in Atlanta, GA
    Mary Jo Lund
    Department of Epidemiology, Rollins School of Public Health, Emory University, 1518 Clifton Road, NE, Atlanta, GA 30322, USA
    Breast Cancer Res Treat 113:357-70. 2009
    ..This study examines association of the ER/PR/HER2 subtypes with race and breast cancer survival...
  52. pmc Complete Khoisan and Bantu genomes from southern Africa
    Stephan C Schuster
    Pennsylvania State University, Center for Comparative Genomics and Bioinformatics, 310 Wartik Lab, University Park, Pennsylvania 16802, USA
    Nature 463:943-7. 2010
    ..Adding the described variants to current databases will facilitate inclusion of southern Africans in medical research efforts, particularly when family and medical histories can be correlated with genome-wide data...
  53. doi Genomic and geographic distribution of SNP-defined runs of homozygosity in Europeans
    Michael Nothnagel
    Institute of Medical Informatics and Statistics, Christian Albrechts University, 24105 Kiel, Germany
    Hum Mol Genet 19:2927-35. 2010
    ..As a consequence, the planning, design and interpretation of ROH-based genetic studies must take sample origin into account in order for such studies to be sensible and valid...
  54. pmc Genetic architecture of transcript-level variation in humans
    Shiwei Duan
    Section of Hematology Oncology, Department of Medicine, University of Chicago, Chicago, IL 60637, USA
    Am J Hum Genet 82:1101-13. 2008
    ..We highlight in the EPHX1 gene a deleterious nonsynonymous SNP that is distantly associated with gene expression of ORMDL3, a susceptibility gene for asthma...
  55. pmc Digital quantification of human eye color highlights genetic association of three new loci
    Fan Liu
    Department of Forensic Molecular Biology, Erasmus University Medical Center, Rotterdam, The Netherlands
    PLoS Genet 6:e1000934. 2010
    ..A model for predicting quantitative eye colors explained over 50% of trait variance in the Rotterdam Study. Over all our data exemplify that fine phenotyping is a useful strategy for finding genes involved in human complex traits...
  56. pmc Impact of common variants of PPARG, KCNJ11, TCF7L2, SLC30A8, HHEX, CDKN2A, IGF2BP2, and CDKAL1 on the risk of type 2 diabetes in 5,164 Indians
    Ganesh Chauhan
    Functional Genomics Unit, Institute of Genomics and Integrative Biology CSIR, Delhi, India
    Diabetes 59:2068-74. 2010
    ..We have studied the association of common variants in these eight genes with type 2 diabetes and related traits in Indians by combining the data from two independent case-control studies...
  57. pmc Common variants in the trichohyalin gene are associated with straight hair in Europeans
    Sarah E Medland
    Queensland Institute of Medical Research, Brisbane 4029, Australia
    Am J Hum Genet 85:750-5. 2009
    ..5x10(-31)). These variants are at their highest frequency in Northern Europeans, paralleling the distribution of the straight-hair EDAR variant in Asian populations...
  58. pmc Acute effect of a single high-fat meal on forearm blood flow, blood pressure and heart rate in healthy male Asians and Caucasians: a pilot study
    Chumjit Bui
    Department of Health Promotion and Education, School of Public Health, Loma Linda University, Loma Linda, CA, USA
    Southeast Asian J Trop Med Public Health 41:490-500. 2010
    ..These findings suggest that a single HF meal may contribute to the detrimental effects on vascular health in Asian males and raises speculation regarding the cumulative impact of a chronic HF diet in this population...
  59. pmc Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder
    Colin A Hodgkinson
    Section of Human Neurogenetics and Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, Rockville, MD, USA
    Am J Hum Genet 75:862-72. 2004
    ..These data support the idea that these apparently distinct disorders have at least a partially convergent etiology and that variation at the DISC1 locus predisposes individuals to a variety of psychiatric disorders...
  60. ncbi Breast cancer in African-American women: differences in tumor biology from European-American women
    Kandace Amend
    Department of Oncological Sciences, Mount Sinai School of Medicine, New York, New York, USA
    Cancer Res 66:8327-30. 2006
    ..An overview of the current literature about racial differences in breast cancer prompts questions for future research to elucidate causes for the apparent disparities in tumor biology...
  61. pmc Color and genomic ancestry in Brazilians
    Flavia C Parra
    Departamento de Bioquimica e Imunologia, Universidade Federal de Minas Gerais, 31270 901 Belo Horizonte, Brazil
    Proc Natl Acad Sci U S A 100:177-82. 2003
    ..Our data suggest that in Brazil, at an individual level, color, as determined by physical evaluation, is a poor predictor of genomic African ancestry, estimated by molecular markers...
  62. ncbi Contextual analysis of breast and cervical cancer screening and factors associated with health care access among United States women, 2002
    Steven S Coughlin
    Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Soc Sci Med 66:260-75. 2008
    ..A significant interaction was also observed between the percentage of county female population who were Hispanic and the percentage who were non-Hispanic Black...
  63. pmc Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide association studies
    Marcel den Hoed
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK
    Diabetes 59:2980-8. 2010
    ..We examined associations of variants in these loci with anthropometric traits in children and adolescents...
  64. pmc Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study
    Christopher J Lessard
    Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA
    Am J Hum Genet 88:83-91. 2011
    ....
  65. ncbi The relationship of ethnicity, socioeconomic factors, and overweight in US adolescents
    Penny Gordon-Larsen
    University of North Carolina, Department of Nutrition, School of Public Health, Chapel Hill, NC 27516 3997, USA
    Obes Res 11:121-9. 2003
    ..To examine the extent to which race/ethnic differences in income and education account for sex-specific disparities in overweight prevalence in white, African American, Hispanic, and Asian U.S. teens...
  66. pmc The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research
    Matthew R Nelson
    GlaxoSmithKline, Research Triangle Park, NC 27709, USA
    Am J Hum Genet 83:347-58. 2008
    ..The genotype and demographic data from this reference sample are freely available through the NCBI database of Genotypes and Phenotypes (dbGaP)...
  67. pmc Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs
    Anke Tonjes
    Department of Medicine, University of Leipzig, Leipzig, Germany
    Hum Mol Genet 18:4662-8. 2009
    ..7 x 10(-8) (beta = 0.949). In conclusion, our GWAS suggests novel loci influencing height. In view of the robust replication in five different cohorts, we propose GPR133 to be a novel gene associated with adult height...
  68. pmc Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility
    Julius Gudmundsson
    deCODE Genetics, Reykjavik, Iceland
    Nat Genet 41:1122-6. 2009
    ..3% of the risk distribution are at a 2.5 times greater risk of developing the disease than members of the general population...
  69. pmc A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2
    Honglin Song
    Cancer Research UK Department of Oncology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK
    Nat Genet 41:996-1000. 2009
    ..82, 95% confidence interval (CI) 0.79-0.86, P(trend) = 5.1 x 10(-19)). The association differs by histological subtype, being strongest for serous ovarian cancers (OR 0.77, 95% CI 0.73-0.81, P(trend) = 4.1 x 10(-21))...
  70. ncbi Contribution of major diseases to disparities in mortality
    Mitchell D Wong
    Division of General Internal Medicine and Health Services Research, University of California at Los Angeles, Los Angeles 90095 1736, USA
    N Engl J Med 347:1585-92. 2002
    ..Mortality from all causes is higher for persons with fewer years of education and for blacks, but it is unknown which diseases contribute most to these disparities...
  71. pmc Candidate gene association resource (CARe): design, methods, and proof of concept
    Kiran Musunuru
    Broad Institute, Cambridge, MA 02142, USA
    Circ Cardiovasc Genet 3:267-75. 2010
    ..The goals of CARe include the discovery of new variants associated with traits using a candidate gene approach and the discovery of new variants using the genome-wide association mapping approach specifically in African Americans...
  72. ncbi Mentholated cigarette smoking inhibits nicotine metabolism
    Neal L Benowitz
    Division of Clinical Pharmacology and Experimental Therapeutics, University of California, San Francisco, Box 1220, San Francisco, CA 94143 1220, USA
    J Pharmacol Exp Ther 310:1208-15. 2004
    ..Our finding of impaired metabolism of nicotine while mentholated cigarette smoking suggests that mentholated cigarette smoking enhances systemic nicotine exposure...
  73. pmc Mentholated cigarettes and smoking habits in whites and blacks
    J E Muscat
    American Health Foundation, Valhalla, New York 10595, USA
    Tob Control 11:368-71. 2002
    ..To determine if cigarette mentholation is associated with the frequency of smoking and with quitting, and whether mentholation explains racial differences in these two smoking behaviours...
  74. ncbi Factors influencing cotinine half-life during smoking abstinence in African American and Caucasian women
    Karen L Ahijevych
    Ohio State University College of Nursing, Columbus 43210, USA
    Nicotine Tob Res 4:423-31. 2002
    ..To improve accuracy in correctly classifying non-smokers with cotinine levels, a period of at least 7 days of smoking abstinence may be warranted...
  75. ncbi Effects of insulin resistance and type 2 diabetes on lipoprotein subclass particle size and concentration determined by nuclear magnetic resonance
    W Timothy Garvey
    Division of Endocrinology and Department of Medicine, Medical University of South Carolina, Charleston 29425, USA
    Diabetes 52:453-62. 2003
    ..It will be important to study whether NMR lipoprotein subclass parameters can be used to manage risk more effectively and prevent cardiovascular disease in patients with the IRS...
  76. pmc Common genetic variation near melatonin receptor MTNR1B contributes to raised plasma glucose and increased risk of type 2 diabetes among Indian Asians and European Caucasians
    John C Chambers
    Department of Epidemiology and Public Health, Imperial College London, London, U K
    Diabetes 58:2703-8. 2009
    ..Fasting plasma glucose and risk of type 2 diabetes are higher among Indian Asians than among European and North American Caucasians. Few studies have investigated genetic factors influencing glucose metabolism among Indian Asians...
  77. pmc Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height
    Matthew B Lanktree
    Department of Medicine and Biochemistry, University of Western Ontario, London, Ontario, N6A 5C1, Canada
    Am J Hum Genet 88:6-18. 2011
    ..Overall, we show that dense coverage of genes for uncommon SNPs, coupled with large-scale meta-analysis, can successfully identify additional variants associated with a common complex trait...
  78. ncbi Older adults' perceived physical activity enablers and barriers: a multicultural perspective
    Anna E Mathews
    Dept of Health and Exercise Science, Furman University, Greenville, SC, USA
    J Aging Phys Act 18:119-40. 2010
    ..Findings suggest several ways to promote PA among older people, including developing exercise programs designed for older adults and health messages promoting existing places and programs older adults can use to engage in PA...
  79. ncbi Racial/ethnic differences in hypertension and hypertension treatment and control in the multi-ethnic study of atherosclerosis (MESA)
    Holly Kramer
    Department of Preventive Medicine, Loyola University, Chicago, Illinois, USA
    Am J Hypertens 17:963-70. 2004
    ..Most previous studies investigating the association between ethnicity and hypertension focused on differences between African Americans and whites and did not include other racial/ethnic groups such as Chinese or Hispanics...
  80. ncbi Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy
    Hyun Hor
    Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland
    Nat Genet 42:786-9. 2010
    ..Cases almost never carried a trans DRB1*1301-DQB1*0603 haplotype (odds ratio = 0.02; P < 6 x 10(-14)). This unexpected protective HLA haplotype suggests a virtually causal involvement of the HLA region in narcolepsy susceptibility...
  81. doi Comprehensive analysis of genomic variation in the LPA locus and its relationship to plasma lipoprotein(a) in South Asians, Chinese, and European Caucasians
    Matthew B Lanktree
    Department of Medicine and Biochemistry, Robarts Research Institute and Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada
    Circ Cardiovasc Genet 3:39-46. 2010
    ..Genomic analysis of LPA, including both single-nucleotide polymorphisms (SNPs) and kringle IV type 2 (KIV-2) copy number, has yet to be performed...
  82. doi Blood pressure and hypertension in relation to levels of serum polychlorinated biphenyls in residents of Anniston, Alabama
    Alexey Goncharov
    Department of Environmental Health Sciences, School of Public Health, University at Albany, Rensselaer, New York 12144, USA
    J Hypertens 28:2053-60. 2010
    ..To determine risk factors for elevated blood pressure and hypertension in residents of Anniston, Alabama who live near a plant that manufactured polychlorinated biphenyls (PCBs)...
  83. pmc Genetic association of insulin-like growth factor-1 polymorphisms with high-grade myopia in an international family cohort
    Ravikanth Metlapally
    Center for Human GeneticsDepartment of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC 27710, USA
    Invest Ophthalmol Vis Sci 51:4476-9. 2010
    ..This study was conducted to determine whether IGF-1 polymorphisms are associated with myopia in a large, international dataset of Caucasian high-grade myopia pedigrees...
  84. ncbi Genetic variation in the SMAD3 gene is associated with hip and knee osteoarthritis
    Ana M Valdes
    Department of Twin Research and Genetic Epidemiology, St Thomas Hospital Campus, King s College London, London SE1 7EH, UK
    Arthritis Rheum 62:2347-52. 2010
    ..We undertook this study to investigate the role of genetic variation in SMAD3 in the risk of large-joint OA in humans...
  85. pmc Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies
    Fernando Rivadeneira
    Department of Internal Medicine, Rotterdam, The Netherlands
    Nat Genet 41:1199-206. 2009
    ..The many SNPs associated with BMD map to genes in signaling pathways with relevance to bone metabolism and highlight the complex genetic architecture that underlies osteoporosis and variation in BMD...
  86. pmc Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size
    Nicole Soranzo
    Human Genetics Department, Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom
    PLoS Genet 5:e1000445. 2009
    ..Further statistical tests in larger numbers of individuals will be required to verify if the height loci affect height preferentially through these subcomponents of height...
  87. pmc Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study
    Rahul C Deo
    Department of Genetics, Harvard Medical School, Boston, MA, USA
    PLoS Genet 5:e1000342. 2009
    ....
  88. pmc Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci
    John B Harley
    Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, Oklahoma 73104, USA
    Nat Genet 40:204-10. 2008
    ..Our results show that numerous genes, some with known immune-related functions, predispose to SLE...
  89. ncbi Coping and distress among women under treatment for early stage breast cancer: comparing African Americans, Hispanics and non-Hispanic Whites
    Jenifer L Culver
    Department of Psychology, University of Miami, Coral Gables, FL 33124 2070, USA
    Psychooncology 11:495-504. 2002
    ..The data also provided evidence of a maladaptive spiral of distress and avoidant coping over time. Although some ethnic differences were identified, findings also point to a great many similarities across groups...
  90. ncbi Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS
    Maureen P Martin
    Basic Research Program, SAIC Frederick, Frederick, Maryland 21702 1201, USA
    Nat Genet 31:429-34. 2002
    ..The strongest synergistic effect of these loci was on progression to depletion of CD4(+) T cells, which suggests that a protective response of NK cells involving KIR3DS1 and its HLA class I ligands begins soon after HIV-1 infection...
  91. ncbi Influence of socioeconomic and cultural factors on racial differences in late-stage presentation of breast cancer
    D R Lannin
    Department of Surgery, Leo W Jenkins Cancer Center, East Carolina University, Greenville, NC 27858, USA
    JAMA 279:1801-7. 1998
    ..Breast cancer mortality is higher among African American women than among white women in the United States, but the reasons for the racial difference are not known...
  92. doi Body size, body composition and fat distribution: comparative analysis of European, Maori, Pacific Island and Asian Indian adults
    Elaine C Rush
    Faculty of Health and Environmental Sciences, Centre for Physical Activity and Nutrition Research, AUT University, Private Bag 92006, Auckland 1020, New Zealand
    Br J Nutr 102:632-41. 2009
    ..The use of universal BMI cut-off points may not be appropriate for the comparison of obesity prevalence between ethnic groups...
  93. doi Lower quit rates among African American and Latino menthol cigarette smokers at a tobacco treatment clinic
    K K Gandhi
    Division of Addiction Psychiatry, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA
    Int J Clin Pract 63:360-7. 2009
    ..Lower rates of smoking cessation and higher rates of lung cancer in African American (AA) smokers may be linked to their preference for mentholated cigarettes...
  94. pmc Racial differences in exposure to environmental tobacco smoke among children
    Stephen E Wilson
    Division of General Internal Medicine, University of Cincinnati, Cincinnati, Ohio, USA
    Environ Health Perspect 113:362-7. 2005
    ..Identifying causes and consequences of increased cotinine may help explain the striking differences in tobacco-related illnesses...
  95. pmc APOA2, dietary fat, and body mass index: replication of a gene-diet interaction in 3 independent populations
    Dolores Corella
    Nutrition and Genomics Laboratory, Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, 711 Washington St, Boston, MA 02111 1524, USA
    Arch Intern Med 169:1897-906. 2009
    ..However, replication has been low. Our aim was to study interaction among a functional APOA2 polymorphism, food intake, and body mass index (BMI) in independent populations to replicate findings and to increase their evidence level...
  96. pmc Correlation of the leptin:adiponectin ratio with measures of insulin resistance in non-diabetic individuals
    F M Finucane
    MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke s Hospital, Cambridge, UK
    Diabetologia 52:2345-9. 2009
    ..We sought to assess the usefulness of the LAR as a measure of insulin resistance in non-diabetic white adults...
  97. pmc Relationship of alcohol consumption and type of alcoholic beverage consumed with plasma lipid levels: differences between Whites and African Americans of the ARIC study
    Kelly A Volcik
    Human Genetics Center, University of Texas Health Science Center, Houston, TX 77030, USA
    Ann Epidemiol 18:101-7. 2008
    ..The influence of different types of alcoholic beverages on plasma lipid levels has been investigated to a lesser extent and in limited populations...
  98. doi Genetic variation in sex hormone genes influences heel ultrasound parameters in middle-aged and elderly men: results from the European Male Aging Study (EMAS)
    Kate L Limer
    ARC Epidemiology Unit, The University of Manchester, Manchester, United Kingdom
    J Bone Miner Res 24:314-23. 2009
    ....
  99. ncbi Menthol cigarettes and risk of lung cancer
    Daniel R Brooks
    Department of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA
    Am J Epidemiol 158:609-16; discussion 617-20. 2003
    ..0 in separate analyses of male, female, Black, and White subjects. The results of this study do not support the hypothesis that smoking menthol cigarettes increases the risk of lung cancer relative to smoking nonmenthol cigarettes...
  100. pmc Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort
    Lavinia Athanasiu
    Institute of Psychiatry, University of Oslo, P O 1130, Blindern, N 0318 Oslo, Norway
    J Psychiatr Res 44:748-53. 2010
    ..The association of ANK3 with schizophrenia is intriguing in light of recent associations of ANK3 with bipolar disorder, thereby supporting the hypothesis of an overlap in genetic susceptibility between these psychopathological entities...
  101. pmc MYH9 is associated with nondiabetic end-stage renal disease in African Americans
    W H Linda Kao
    Department of Epidemiology, School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21287, USA
    Nat Genet 40:1185-92. 2008
    ....

Research Grants87

  1. SEER RRSS #4: Cancer in Arab American Estimating Rates and Fostering Research
    Ann Schwartz; Fiscal Year: 2009
    ..S. there will be the ability to discern differences in rates between the Middle East, first generation immigrants and more acculturated U.S. Middle Easterners. ..
  2. EFFICACY OF MOTIVATIONAL INTERVIEW TO LOWER DIABETES RISK IN AFRICAN AMERICANS
    LEWIS BLUE; Fiscal Year: 2011
    ..1994). Therefore, GAS will be used to monitor individual behavior change, provide feedback to the Ml participants, and to focus the motivational interview intervention. ..
  3. Gene Networks for Prostate Cancer Progression
    Leif Peterson; Fiscal Year: 2004
    ..Characterization of the FGFR1 and FGFR2 pathways in prostate cancer will contribute to the molecular understanding and early detection of patients that may experience rapid progression of metastases. ..
  4. Gene Networks for Prostate Cancer Progression
    Leif Peterson; Fiscal Year: 2005
    ..Characterization of the FGFR1 and FGFR2 pathways in prostate cancer will contribute to the molecular understanding and early detection of patients that may experience rapid progression of metastases. ..
  5. Gene Networks for Prostate Cancer Progression
    Leif Peterson; Fiscal Year: 2003
    ..Characterization of the FGFR1 and FGFR2 pathways in prostate cancer will contribute to the molecular understanding and early detection of patients that may experience rapid progression of metastases. ..
  6. Culturally Adapted Strategies to Enhance Kidney Donation in Native Communities
    Dedra S Buchwald; Fiscal Year: 2012
    ....
  7. Epidemiology of CHD of Men Aged 40+ in US, Hawaii, Japan
    Akira Sekikawa; Fiscal Year: 2009
    ....
  8. Epidemiology of CHD of Men Aged 40+ in US, Hawaii, Japan
    Akira Sekikawa; Fiscal Year: 2010
    ....
  9. JACKSON HEART STUDY
    HERMAN ALFRED TAYLOR; Fiscal Year: 2009
    ..abstract_text> ..
  10. Race, Ethnicity, Nativity and Housing Outcomes in Los Angeles
    EILEEN MCCONNELL; Fiscal Year: 2009
    ....
  11. JACKSON HEART STUDY
    Asoka Srinivasan; Fiscal Year: 2010
    ..abstract_text> ..
  12. JACKSON HEART STUDY
    ASOKA S SRINIVASAN; Fiscal Year: 2011
    ..abstract_text> ..
  13. JACKSON HEART STUDY
    Herman Taylor; Fiscal Year: 2010
    ..abstract_text> ..
  14. Race, Ethnicity, Nativity and Housing Outcomes in Los Angeles
    EILEEN DIAZ MCCONNELL; Fiscal Year: 2010
    ....
  15. JACKSON HEART STUDY
    HERMAN ALFRED TAYLOR; Fiscal Year: 2009
    ..abstract_text> ..
  16. Sources of Change and Stability in Low-Income Black Marriages
    BENJAMIN REUVEN KARNEY; Fiscal Year: 2010
    ..These data will be combined with data from an ongoing study of low-income Hispanic newlyweds in order to identify the sources of differences in marital outcomes for these two similarly underprivileged groups ..
  17. Sources of Change and Stability in Low-Income Black Marriages
    BENJAMIN KARNEY; Fiscal Year: 2009
    ..These data will be combined with data from an ongoing study of low-income Hispanic newlyweds in order to identify the sources of differences in marital outcomes for these two similarly underprivileged groups ..
  18. UNIVERSITY OF NEW MEXICO CANCER CENTER PLANNING GRANT
    Cheryl Willman; Fiscal Year: 2000
    ..abstract_text> ..
  19. UNIVERSITY OF NEW MEXICO CANCER CENTER PLANNING GRANT
    Cheryl Willman; Fiscal Year: 2001
    ..abstract_text> ..
  20. UNIVERSITY OF NEW MEXICO CANCER CENTER PLANNING GRANT
    Cheryl Willman; Fiscal Year: 2002
    ..abstract_text> ..
  21. UNIVERSITY OF NEW MEXICO CANCER CENTER PLANNING GRANT
    Cheryl Willman; Fiscal Year: 2003
    ..abstract_text> ..
  22. UNIVERSITY OF NEW MEXICO CANCER CENTER PLANNING GRANT
    Cheryl Willman; Fiscal Year: 2004
    ..abstract_text> ..
  23. HCV TREATMENT IN AFRICAN AMERICANS VS NON HISPANIC WHIT*
    Lennox Jeffers; Fiscal Year: 2003
    ..SPECIFIC AIM 7. To identify sociodemographic (e.g., age, education income, gender, ethnicity) and psychosocial (e.g., anxiety, depression, coping) predictors of adherence to treatment and virologic response to HCV RNA. ..
  24. HCV TREATMENT IN AFRICAN AMERICANS VS NON HISPANIC WHIT*
    Lennox Jeffers; Fiscal Year: 2004
    ..SPECIFIC AIM 7. To identify sociodemographic (e.g., age, education income, gender, ethnicity) and psychosocial (e.g., anxiety, depression, coping) predictors of adherence to treatment and virologic response to HCV RNA. ..
  25. HCV TREATMENT IN AFRICAN AMERICANS VS NON HISPANIC WHIT*
    Lennox Jeffers; Fiscal Year: 2002
    ..SPECIFIC AIM 7. To identify sociodemographic (e.g., age, education income, gender, ethnicity) and psychosocial (e.g., anxiety, depression, coping) predictors of adherence to treatment and virologic response to HCV RNA. ..
  26. HCV TREATMENT IN AFRICAN AMERICANS VS NON HISPANIC WHIT*
    Lennox Jeffers; Fiscal Year: 2001
    ..SPECIFIC AIM 7. To identify sociodemographic (e.g., age, education income, gender, ethnicity) and psychosocial (e.g., anxiety, depression, coping) predictors of adherence to treatment and virologic response to HCV RNA. ..
  27. HCV TREATMENT IN AFRICAN AMERICANS VS NON HISPANIC WHIT*
    Lennox Jeffers; Fiscal Year: 2004
    ..SPECIFIC AIM 7. To identify sociodemographic (e.g., age, education income, gender, ethnicity) and psychosocial (e.g., anxiety, depression, coping) predictors of adherence to treatment and virologic response to HCV RNA. ..
  28. HCV TREATMENT IN AFRICAN AMERICANS VS NON HISPANIC WHIT*
    Lennox Jeffers; Fiscal Year: 2005
    ..SPECIFIC AIM 7. To identify sociodemographic (e.g., age, education income, gender, ethnicity) and psychosocial (e.g., anxiety, depression, coping) predictors of adherence to treatment and virologic response to HCV RNA. ..
  29. Disparities in cervical cancer precursors and deregulation of imprinted genes
    Susan Kay Murphy; Fiscal Year: 2012
    ..Data from this study will elucidate the role of epigenetic deregulation in CIN2+ and inform triage decisions, reducing disparities in cervical cancer incidence and mortality. ..
  30. Disparities in cervical cancer precursors and deregulation of imprinted genes
    Susan Kay Murphy; Fiscal Year: 2011
    ..Data from this study will elucidate the role of epigenetic deregulation in CIN2+ and inform triage decisions, reducing disparities in cervical cancer incidence and mortality. ..
  31. Disparities in cervical cancer precursors and deregulation of imprinted genes
    Susan Kay Murphy; Fiscal Year: 2010
    ..Data from this study will elucidate the role of epigenetic deregulation in CIN2+ and inform triage decisions, reducing disparities in cervical cancer incidence and mortality. ..
  32. Promoting Walking in African Americans with Peripheral Arterial Disease
    TRACIE CHIANTI COLLINS; Fiscal Year: 2010
    ....
  33. RACE AND ETHNIC DIFFERENCES IN U.S. BIRTH OUTCOMES
    Michael Grossman; Fiscal Year: 1990
    ..Can the upward trend in the percentage of illegitimate births explain the modest decline in the percentage of light births in the face of a rapid increase over time in the prompt initiation of prenatal care, especially among minorities?..
  34. A dataset for the study of the social determinants of health.
    Peter Muennig; Fiscal Year: 2009
    ..This dataset will greatly advance scientific understanding of the social causation of disease and health disparities. ..
  35. A dataset for the study of the social determinants of health.
    Peter A Muennig; Fiscal Year: 2010
    ..This dataset will greatly advance scientific understanding of the social causation of disease and health disparities. ..
  36. Transplant Social Worker Support for Live Kidney Donation in African Americans
    LEIGH E BOULWARE; Fiscal Year: 2012
    ..This proposal will study two novel social worker led interventions (one behavioral, one financial) to improve live kidney donation for African Americans in need of a kidney transplant. ..
  37. Ethnic Differences in Responses to Painful Stimuli
    Roger Fillingim; Fiscal Year: 2009
    ....
  38. GENETICS OF BLOOD PRESSURE CONTROL IN MEXICAN AMERICANS
    Larry Atwood; Fiscal Year: 1999
    ..Finally, all loci that have detectable effects on the intermediate phenotypes will be tested for their effects on blood pressure. ..
  39. GENETICS OF BLOOD PRESSURE CONTROL IN MEXICAN AMERICANS
    Larry Atwood; Fiscal Year: 2000
    ..Finally, all loci that have detectable effects on the intermediate phenotypes will be tested for their effects on blood pressure. ..
  40. Genotypes, Haplotypes, and Blood Pressure Change from Childhood to Adulthood
    DAVID HALLMAN; Fiscal Year: 2009
    ....
  41. VIRAHEP-C Clinical Center
    Hari Conjeevaram; Fiscal Year: 2003
    ..abstract_text> ..
  42. Reducing disparities in colorectal cancer screening in Vietnamese Americans
    Bang Nguyen; Fiscal Year: 2009
    ....
  43. VIRAHEP-C Clinical Center
    Hari Conjeevaram; Fiscal Year: 2004
    ..abstract_text> ..
  44. VIRAHEP-C Clinical Center
    Anna Lok; Fiscal Year: 2005
    ..abstract_text> ..
  45. VIRAHEP-C Clinical Center
    Hari Conjeevaram; Fiscal Year: 2002
    ..abstract_text> ..
  46. Reducing disparities in colorectal cancer screening in Vietnamese Americans
    Bang Nguyen; Fiscal Year: 2009
    ..abstract_text> ..
  47. VIRAHEP-C Clinical Center
    Hari Conjeevaram; Fiscal Year: 2001
    ..abstract_text> ..
  48. Dose-dependent anti-inflammatory effects of vitamin D in a human gingivitis model
    Raul Garcia; Fiscal Year: 2007
    ....
  49. Dose-dependent anti-inflammatory effects of vitamin D in a human gingivitis model
    Raul Garcia; Fiscal Year: 2009
    ....
  50. THE AGING OF BLACK VETERANS
    DORA COSTA; Fiscal Year: 2002
    ..The findings will also help forecast future retirement, mortality, and disability trends that will aid in the development of health and pension policies. ..
  51. THE AGING OF BLACK VETERANS
    DORA COSTA; Fiscal Year: 2001
    ..The findings will also help forecast future retirement, mortality, and disability trends that will aid in the development of health and pension policies. ..
  52. Intensive Outpatient v. Outpatient Treatment with Buprenorphine among African Ame
    Shannon Mitchell; Fiscal Year: 2009
    ....
  53. Intensive Outpatient v. Outpatient Treatment with Buprenorphine among African Ame
    Shannon Gwin Mitchell; Fiscal Year: 2010
    ....
  54. PHARMACOKINETICS AND PHARMACODYNAMICS OF NICOTINE
    Neal L Benowitz; Fiscal Year: 2010
    ..An ultimate objective is to use this knowledge to aid in the development of more effective smoking cessation interventions for African-Americans. ..
  55. Racial & Ethnic Disparities in Incidence and Inpatient Outcomes of Acute Stroke
    Amresh D Hanchate; Fiscal Year: 2010
    ..For effective targeting of interventions and public policy, our study aims to use evidence to identify and prioritize modifiable factors appropriate for each minority cohort. ..
  56. Disparities in CHD in the Jackson Heart Study
    Mario Sims; Fiscal Year: 2010
    ..This research will also show which factors health policy makers need to focus on in order to address and eliminate CHD disparities. ..
  57. PHARMACOKINETICS AND PHARMACODYNAMICS OF NICOTINE
    Neal Benowitz; Fiscal Year: 2009
    ..An ultimate objective is to use this knowledge to aid in the development of more effective smoking cessation interventions for African-Americans. ..
  58. Disparities in CHD in the Jackson Heart Study
    Mario Sims; Fiscal Year: 2007
    ..This research will also show which factors health policy makers need to focus on in order to address and eliminate CHD disparities. ..
  59. Racial & Ethnic Disparities in Incidence and Inpatient Outcomes of Acute Stroke
    Amresh Hanchate; Fiscal Year: 2009
    ..For effective targeting of interventions and public policy, our study aims to use evidence to identify and prioritize modifiable factors appropriate for each minority cohort. ..
  60. Disparities in CHD in the Jackson Heart Study
    Mario Sims; Fiscal Year: 2009
    ..This research will also show which factors health policy makers need to focus on in order to address and eliminate CHD disparities. ..
  61. Disparities in CHD in the Jackson Heart Study
    Mario Sims; Fiscal Year: 2006
    ..This research will also show which factors health policy makers need to focus on in order to address and eliminate CHD disparities. ..
  62. Resistance to Antiviral Therapy in Chronic Hepatitis C
    Norah Terrault; Fiscal Year: 2003
    ..Moreover, the methodologies developed for patient outreach within the context of this collaborative study will serve as a model for enhancing participation of African Americans in clinical research. ..
  63. Resistance to Antiviral Therapy in Chronic Hepatitis C
    Norah Terrault; Fiscal Year: 2005
    ..Moreover, the methodologies developed for patient outreach within the context of this collaborative study will serve as a model for enhancing participation of African Americans in clinical research. ..
  64. Resistance to Antiviral Therapy in Chronic Hepatitis C
    Norah Terrault; Fiscal Year: 2004
    ..Moreover, the methodologies developed for patient outreach within the context of this collaborative study will serve as a model for enhancing participation of African Americans in clinical research. ..
  65. Resistance to Antiviral Therapy in Chronic Hepatitis C
    Norah Terrault; Fiscal Year: 2001
    ..Moreover, the methodologies developed for patient outreach within the context of this collaborative study will serve as a model for enhancing participation of African Americans in clinical research. ..
  66. Resistance to Antiviral Therapy in Chronic Hepatitis C
    Norah Terrault; Fiscal Year: 2002
    ..Moreover, the methodologies developed for patient outreach within the context of this collaborative study will serve as a model for enhancing participation of African Americans in clinical research. ..
  67. INCIDENCE OF DIABETES AND CVD IN MEXICAN AMERICANS
    Michael Stern; Fiscal Year: 2002
    ..The investigators note that this will aid in the interpretation of data relating to possible ethnic differences in cause-specific mortality based on death certificate coding. ..
  68. INCIDENCE OF DIABETES AND CVD IN MEXICAN AMERICANS
    Michael Stern; Fiscal Year: 1999
    ..The investigators note that this will aid in the interpretation of data relating to possible ethnic differences in cause-specific mortality based on death certificate coding. ..
  69. INCIDENCE OF DIABETES AND CVD IN MEXICAN AMERICANS
    Michael Stern; Fiscal Year: 2001
    ..The investigators note that this will aid in the interpretation of data relating to possible ethnic differences in cause-specific mortality based on death certificate coding. ..
  70. INCIDENCE OF DIABETES AND CVD IN MEXICAN AMERICANS
    Michael Stern; Fiscal Year: 2000
    ..The investigators note that this will aid in the interpretation of data relating to possible ethnic differences in cause-specific mortality based on death certificate coding. ..
  71. Understanding Race and Culture in Living Donor Kidney Transplantation
    Larissa Myaskovsky; Fiscal Year: 2009
    ..Findings from this study are needed in order to develop patient, provider, and system-level interventions to increase rates of LDKT and improve post-transplant health outcomes among African Americans. ..
  72. Using Doctor-Patient Teams to Reduce Health Disparities
    Louis Penner; Fiscal Year: 2006
    ..If successful, the study should provide an exportable means of improving communication between physicians and minority group patients and reducing disparities in health care. [unreadable] [unreadable] [unreadable]..
  73. Using Doctor-Patient Teams to Reduce Health Disparities
    Louis Penner; Fiscal Year: 2007
    ..If successful, the study should provide an exportable means of improving communication between physicians and minority group patients and reducing disparities in health care. [unreadable] [unreadable] [unreadable]..
  74. Mexican-American Trial of Community Health Workers-MATCH
    Steven Rothschild; Fiscal Year: 2004
    ..Future translation of this research will be facilitated by a well-standardized intervention and rigorous monitoring of CHW encounters through audiotapes and documentation of intervention worksheets. ..
  75. Mexican-American Trial of Community Health Workers-MATCH
    Steven Rothschild; Fiscal Year: 2007
    ..Future translation of this research will be facilitated by a well-standardized intervention and rigorous monitoring of CHW encounters through audiotapes and documentation of intervention worksheets. [unreadable] [unreadable]..
  76. Mexican-American Trial of Community Health Workers-MATCH
    Steven Rothschild; Fiscal Year: 2005
    ..Future translation of this research will be facilitated by a well-standardized intervention and rigorous monitoring of CHW encounters through audiotapes and documentation of intervention worksheets. ..
  77. Mexican-American Trial of Community Health Workers-MATCH
    Steven Rothschild; Fiscal Year: 2006
    ..Future translation of this research will be facilitated by a well-standardized intervention and rigorous monitoring of CHW encounters through audiotapes and documentation of intervention worksheets. [unreadable] [unreadable]..
  78. Racial/Ethnic Disparities and High Volume Hospitals
    Bradford Gray; Fiscal Year: 2003
    ..S. Methodologically, we will explore a number of measurement issues, including the effects of alternative ways of operationalizing high volume and proximity. ..
  79. STROKE INCIDENCE AND RISK FACTORS IN A TRI-ETHNIC REGION
    Ralph Sacco; Fiscal Year: 2009
    ..We need to understand the importance of these conditions in predicting stroke, MI, vascular death, and determining cognitive decline among minority populations. ..
  80. STROKE INCIDENCE AND RISK FACTORS IN A TRI-ETHNIC REGION
    Ralph Sacco; Fiscal Year: 2009
    ..We need to understand the importance of these conditions in predicting stroke, MI, vascular death, and determining cognitive decline among minority populations. ..
  81. Information and Financial Interventions for Kidney Donation in African Americans
    LEIGH BOULWARE; Fiscal Year: 2009
    ....
  82. Characterizing Mitochondrial DNA Susceptibility to Breast, Colorectal, and Prosta
    Iona Cheng; Fiscal Year: 2009
    ..In addition, we will evaluate heterogeneity of effects by disease sub-groups, environmental factors and known genetic risk factors. ..
  83. Information and Financial Interventions for Kidney Donation in African Americans
    LEIGH BOULWARE; Fiscal Year: 2009
    ....