Summary: A person 13 to 18 years of age.

Top Publications

  1. Idele P, Gillespie A, Porth T, Suzuki C, Mahy M, Kasedde S, et al. Epidemiology of HIV and AIDS among adolescents: current status, inequities, and data gaps. J Acquir Immune Defic Syndr. 2014;66 Suppl 2:S144-53 pubmed publisher
    ..To examine levels and patterns of HIV prevalence, knowledge, sexual behavior, and coverage of selected HIV services among adolescents aged 10-19 years and highlight data gaps and challenges...
  2. Sonne C, Gustavson K, Riget F, Dietz R, Krüger T, Bonefeld Jørgensen E. Physiologically based pharmacokinetic modeling of POPs in Greenlanders. Environ Int. 2014;64:91-7 pubmed publisher
    ..Based on these results we suggest that PBPK modeling is implemented as a tool in future human health exposure and effect assessments in Greenland. ..
  3. Kashanian M, Hassan M, Roohi M, Yousefi H. Maternal outcomes of intimate partner violence during pregnancy: study in Iran. Public Health. 2014;128:410-5 pubmed publisher
  4. Ganchimeg T, Ota E, Morisaki N, Laopaiboon M, Lumbiganon P, Zhang J, et al. Pregnancy and childbirth outcomes among adolescent mothers: a World Health Organization multicountry study. BJOG. 2014;121 Suppl 1:40-8 pubmed publisher
    ..Risk of adverse pregnancy outcomes among adolescent mothers. A total of 124 446 mothers aged ?24 years and their infants were analysed...
  5. Stern D, Piernas C, Barquera S, Rivera J, Popkin B. Caloric beverages were major sources of energy among children and adults in Mexico, 1999-2012. J Nutr. 2014;144:949-56 pubmed publisher
    ..Because caloric soda is currently 1 of the top beverages consumed, a 10% tax on SSBs might help to significantly reduce added sugars intake in Mexico. ..
  6. Reed E, Miller E, Raj A, Decker M, Silverman J. Teen dating violence perpetration and relation to STI and sexual risk behaviours among adolescent males. Sex Transm Infect. 2014;90:322-4 pubmed publisher
    ..b>Adolescent male survey participants (N=134) were aged 14-20?years, recruited from urban health centres...
  7. Mavedzenge S, Luecke E, Ross D. Effective approaches for programming to reduce adolescent vulnerability to HIV infection, HIV risk, and HIV-related morbidity and mortality: a systematic review of systematic reviews. J Acquir Immune Defic Syndr. 2014;66 Suppl 2:S154-69 pubmed publisher
    ..There is a pressing need for more rigorous research on how best to enable adolescents to access these effective interventions. ..
  8. Schunter B, Cheng W, Kendall M, Marais H. Lessons learned from a review of interventions for adolescent and young key populations in Asia Pacific and opportunities for programming. J Acquir Immune Defic Syndr. 2014;66 Suppl 2:S186-92 pubmed publisher
    ..The review was initiated to identify interventions in the region with demonstrated or potential impact for adolescent and young key populations (YKP) looking at the role of individual and structural factors in accessibility and ..
  9. Hayes R, Ayles H, Beyers N, Sabapathy K, Floyd S, Shanaube K, et al. HPTN 071 (PopART): rationale and design of a cluster-randomised trial of the population impact of an HIV combination prevention intervention including universal testing and treatment - a study protocol for a cluster randomised trial. Trials. 2014;15:57 pubmed publisher
    ..Importantly, the three-arm design will enable assessment of how much could be achieved by optimal delivery of current policies and the costs and benefits of extending this to UTT. NCT01900977. ..

More Information


  1. Sulheim D, Fagermoen E, Winger A, Andersen A, Godang K, Muller F, et al. Disease mechanisms and clonidine treatment in adolescent chronic fatigue syndrome: a combined cross-sectional and randomized clinical trial. JAMA Pediatr. 2014;168:351-60 pubmed publisher
    ..69; P?=?.02) compared with the CFS placebo group. Adolescent CFS is associated with enhanced sympathetic nervous activity, low-grade systemic inflammation, attenuated ..
  2. Lundberg P, Karow A, Nienhold R, Looser R, Hao Shen H, Nissen I, et al. Clonal evolution and clinical correlates of somatic mutations in myeloproliferative neoplasms. Blood. 2014;123:2220-8 pubmed publisher
    ..Our data show that comprehensive mutational screening at diagnosis and during follow-up has considerable potential to identify patients at high risk of disease progression. ..
  3. Viborg N, Wångby Lundh M, Lundh L. Reciprocal prospective associations between disordered eating and other psychological problems in a community sample of Swedish adolescent girls. Eat Behav. 2014;15:159-63 pubmed publisher
    ..difficulties and body satisfaction were prospectively studied in a community sample of 13-15 year old adolescent girls (N=428)...
  4. Hemphälä M, Hodgins S. Do psychopathic traits assessed in mid-adolescence predict mental health, psychosocial, and antisocial, including criminal outcomes, over the subsequent 5 years?. Can J Psychiatry. 2014;59:40-9 pubmed
    ..L’information sur le niveau de ces traits peut être utile pour planifier un traitement. ..
  5. Frederick C, Snellman K, Putnam R. Increasing socioeconomic disparities in adolescent obesity. Proc Natl Acad Sci U S A. 2014;111:1338-42 pubmed publisher
    ..Additional analyses suggest that socioeconomic differences in the levels of physical activity, as well as differences in calorie intake, may have contributed to the growing obesity gradient. ..
  6. COOK B, Wayne G, Kafali E, Liu Z, Shu C, Flores M. Trends in smoking among adults with mental illness and association between mental health treatment and smoking cessation. JAMA. 2014;311:172-82 pubmed publisher
    ..This suggests that tobacco control policies and cessation interventions targeting the general population have not worked as effectively for persons with mental illness. ..
  7. Dabelea D, Mayer Davis E, Saydah S, Imperatore G, Linder B, Divers J, et al. Prevalence of type 1 and type 2 diabetes among children and adolescents from 2001 to 2009. JAMA. 2014;311:1778-86 pubmed publisher
    ..Between 2001 and 2009 in 5 areas of the United States, the prevalence of both type 1 and type 2 diabetes among children and adolescents increased. Further studies are required to determine the causes of these increases. ..
  8. Ng M, Freeman M, Fleming T, Robinson M, Dwyer Lindgren L, Thomson B, et al. Smoking prevalence and cigarette consumption in 187 countries, 1980-2012. JAMA. 2014;311:183-92 pubmed publisher
    ..As tobacco remains a threat to the health of the world's population, intensified efforts to control its use are needed. ..
  9. Browning A, Lewis A, Whiteside S. Predicting women at risk for developing obstetric fistula: a fistula index? An observational study comparison of two cohorts. BJOG. 2014;121:604-9 pubmed publisher
    ..To ascertain if a predictor of obstructed labour and obstetric fistula (OF) occurrence could be devised...
  10. Patton G, Coffey C, Romaniuk H, MacKinnon A, Carlin J, Degenhardt L, et al. The prognosis of common mental disorders in adolescents: a 14-year prospective cohort study. Lancet. 2014;383:1404-11 pubmed publisher
    Most adults with common mental disorders report their first symptoms before 24 years of age. Although adolescent anxiety and depression are frequent, little clarity exists about which syndromes persist into adulthood or resolve before ..
  11. Horne J, Flannery R, Usman S. Adolescent idiopathic scoliosis: diagnosis and management. Am Fam Physician. 2014;89:193-8 pubmed
    b>Adolescent idiopathic scoliosis is the most common form of scoliosis, affecting approximately 2% to 4% of adolescents...
  12. Xing W, Liao Q, Viboud C, Zhang J, Sun J, Wu J, et al. Hand, foot, and mouth disease in China, 2008-12: an epidemiological study. Lancet Infect Dis. 2014;14:308-318 pubmed publisher
  13. Biton V, Berkovic S, Abou Khalil B, Sperling M, Johnson M, Lu S. Brivaracetam as adjunctive treatment for uncontrolled partial epilepsy in adults: a phase III randomized, double-blind, placebo-controlled trial. Epilepsia. 2014;55:57-66 pubmed publisher
    ..Adjunctive BRV at a daily dose of 50 mg was associated with statistically significant reductions in seizure frequency compared with PBO. All doses of BRV showed good tolerability throughout the study. ..
  14. Keeble S, Abel G, Saunders C, McPhail S, Walter F, Neal R, et al. Variation in promptness of presentation among 10,297 patients subsequently diagnosed with one of 18 cancers: evidence from a National Audit of Cancer Diagnosis in Primary Care. Int J Cancer. 2014;135:1220-8 pubmed publisher
    ..These findings can help to prioritise public awareness initiatives and research focusing on symptoms of cancers associated with greater risk of non-prompt presentation, such as oro-pharyngeal and oesophageal cancer. ..
  15. Hedström A, Lima Bomfim I, Barcellos L, Gianfrancesco M, Schaefer C, Kockum I, et al. Interaction between adolescent obesity and HLA risk genes in the etiology of multiple sclerosis. Neurology. 2014;82:865-72 pubmed publisher
    ..Prevention of adolescent obesity may thus lower the risk of developing MS, predominantly among people with a genetic susceptibility to ..
  16. Vora N, Holman R, Mehal J, Steiner C, Blanton J, Sejvar J. Burden of encephalitis-associated hospitalizations in the United States, 1998-2010. Neurology. 2014;82:443-51 pubmed publisher
    ..To estimate the burden of encephalitis-associated hospitalizations in the United States for 1998-2010...
  17. Ogden C, Carroll M, Kit B, Flegal K. Prevalence of childhood and adult obesity in the United States, 2011-2012. JAMA. 2014;311:806-14 pubmed publisher
    ..More than one-third of adults and 17% of youth in the United States are obese, although the prevalence remained stable between 2003-2004 and 2009-2010...
  18. Ashley E, Dhorda M, Fairhurst R, Amaratunga C, Lim P, Suon S, et al. Spread of artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med. 2014;371:411-23 pubmed publisher
    ..Funded by the U.K. Department of International Development and others; number, NCT01350856.). ..
  19. Lawlor D, Callaway M, Macdonald Wallis C, Anderson E, Fraser A, Howe L, et al. Nonalcoholic fatty liver disease, liver fibrosis, and cardiometabolic risk factors in adolescence: a cross-sectional study of 1874 general population adolescents. J Clin Endocrinol Metab. 2014;99:E410-7 pubmed publisher
    The impact of adolescent nonalcoholic fatty liver disease (NAFLD) on health, independent of fat mass, is unclear...
  20. Stoner R, Chow M, Boyle M, Sunkin S, Mouton P, Roy S, et al. Patches of disorganization in the neocortex of children with autism. N Engl J Med. 2014;370:1209-1219 pubmed publisher
    ..Our data support a probable dysregulation of layer formation and layer-specific neuronal differentiation at prenatal developmental stages. (Funded by the Simons Foundation and others.). ..
  21. Caci H, Morin A, Tran A. Prevalence and correlates of attention deficit hyperactivity disorder in adults from a French community sample. J Nerv Ment Dis. 2014;202:324-32 pubmed publisher
    ..Adults can be screened for ADHD symptoms using the ASRS; negative long-term outcomes should be assessed in patients' relatives too. ..
  22. Hainsworth G, Engel D, Simon C, Rahimtoola M, Ghiron L. Scale-up of adolescent contraceptive services: lessons from a 5-country comparative analysis. J Acquir Immune Defic Syndr. 2014;66 Suppl 2:S200-8 pubmed publisher
    ..faces in accessing health services and highlights a gap in the availability of appropriate services, including adolescent-friendly contraceptive services (AFCS)...
  23. Kapogiannis B, Legins K, Chandan U, Lee S. Evidence-based programming for adolescent HIV prevention and care: operational research to inform best practices. J Acquir Immune Defic Syndr. 2014;66 Suppl 2:S228-35 pubmed publisher
    ..Operational research among adolescent populations affected by HIV is critically needed to close the knowledge and investment gaps, and scale-up ..
  24. Paton N, Kityo C, Hoppe A, Reid A, Kambugu A, Lugemwa A, et al. Assessment of second-line antiretroviral regimens for HIV therapy in Africa. N Engl J Med. 2014;371:234-47 pubmed publisher
    ..Removing the NRTIs or replacing them with raltegravir may provide a benefit...
  25. Magill S, Edwards J, Bamberg W, Beldavs Z, Dumyati G, Kainer M, et al. Multistate point-prevalence survey of health care-associated infections. N Engl J Med. 2014;370:1198-208 pubmed publisher
    ..We conducted a prevalence survey in 10 geographically diverse states to determine the prevalence of health care-associated infections in acute care hospitals and generate updated estimates of the national burden of such infections...
  26. Bandopadhayay P, Bergthold G, London W, Goumnerova L, Morales La Madrid A, Marcus K, et al. Long-term outcome of 4,040 children diagnosed with pediatric low-grade gliomas: an analysis of the Surveillance Epidemiology and End Results (SEER) database. Pediatr Blood Cancer. 2014;61:1173-9 pubmed publisher
    ..Treatment strategies for pediatric tumors should therefore aim for disease control during childhood and adolescence with an emphasis on minimizing long-term treatment induced toxicities. ..
  27. Zanoni B, Mayer K. The adolescent and young adult HIV cascade of care in the United States: exaggerated health disparities. AIDS Patient Care STDS. 2014;28:128-35 pubmed publisher
    ..We explore the cascade of care from HIV diagnosis through viral suppression for HIV-infected adolescents and young adults in the United States to highlight areas for improvement in the poor engagement of the infected youth population...
  28. D Onofrio B, Rickert M, Frans E, Kuja Halkola R, Almqvist C, Sjölander A, et al. Paternal age at childbearing and offspring psychiatric and academic morbidity. JAMA Psychiatry. 2014;71:432-8 pubmed publisher
    ..individuals born in Sweden in 1973-2001 (N = 2,615,081), with subsets of the data used to predict childhood or adolescent morbidity...
  29. Rotunno G, Mannarelli C, Guglielmelli P, Pacilli A, Pancrazzi A, Pieri L, et al. Impact of calreticulin mutations on clinical and hematological phenotype and outcome in essential thrombocythemia. Blood. 2014;123:1552-5 pubmed publisher
    ..Genotyping for CALR mutations represents a novel useful tool for establishing a clonal myeloproliferative disorder in JAK2 and MPL wt patients with thrombocytosis and may have prognostic and therapeutic relevance. ..
  30. Welch A, MacGregor A, Minihane A, Skinner J, Valdes A, Spector T, et al. Dietary fat and fatty acid profile are associated with indices of skeletal muscle mass in women aged 18-79 years. J Nutr. 2014;144:327-34 pubmed publisher
    ..These findings indicate that a dietary fat profile already associated with cardiovascular disease protection may also be beneficial for conservation of skeletal muscle mass. ..
  31. Ward E, DeSantis C, Robbins A, Kohler B, Jemal A. Childhood and adolescent cancer statistics, 2014. CA Cancer J Clin. 2014;64:83-103 pubmed publisher
    ..In addition to cancer statistics, this article will provide an overview of risk factors, symptoms, treatment, and long-term and late effects for common pediatric cancers...
  32. Wang C, Chen P, Zhuang J. A national survey of physical activity and sedentary behavior of Chinese city children and youth using accelerometers. Res Q Exerc Sport. 2013;84 Suppl 2:S12-28 pubmed
    ..No differences in PA and SB were found across different BMI categories. The findings warn of the insufficiency of PA and the excess of SB in Chinese city children and youth. ..
  33. Cross M, Smith E, Hoy D, Nolte S, Ackerman I, Fransen M, et al. The global burden of hip and knee osteoarthritis: estimates from the global burden of disease 2010 study. Ann Rheum Dis. 2014;73:1323-30 pubmed publisher
    ..With the aging and increasing obesity of the world's population, health professions need to prepare for a large increase in the demand for health services to treat hip and knee OA. ..
  34. Specht I, Toft G, Hougaard K, Lindh C, Lenters V, Jonsson B, et al. Associations between serum phthalates and biomarkers of reproductive function in 589 adult men. Environ Int. 2014;66:146-56 pubmed publisher
    ..Metabolic pathways differed significantly between the three study sites, but without major effect on semen quality or reproductive hormones. ..
  35. Mburu G, Hodgson I, Kalibala S, Haamujompa C, Cataldo F, Lowenthal E, et al. Adolescent HIV disclosure in Zambia: barriers, facilitators and outcomes. J Int AIDS Soc. 2014;17:18866 pubmed publisher
    ..Further research is needed to explore the potential role of trusted family members in contributing to the disclosure process. ..
  36. Colen C, Ramey D. Is breast truly best? Estimating the effects of breastfeeding on long-term child health and wellbeing in the United States using sibling comparisons. Soc Sci Med. 2014;109:55-65 pubmed publisher
  37. Gidding S, Bacha F, Bjornstad P, Levitt Katz L, Levitsky L, Lynch J, et al. Cardiac Biomarkers in Youth with Type 2 Diabetes Mellitus: Results from the TODAY Study. J Pediatr. 2018;192:86-92.e5 pubmed publisher
    ..Elevated serum concentrations of cardiac biomarkers were common in youth with type 2 diabetes, but their clinical significance is unclear and will require further long-term study. ClinicalTrials.govNCT00081328. ..
  38. Cortaredona S, Ventelou B. The extra cost of comorbidity: multiple illnesses and the economic burden of non-communicable diseases. BMC Med. 2017;15:216 pubmed publisher
  39. Katsurada N, Suzuki M, Aoshima M, Yaegashi M, Ishifuji T, Asoh N, et al. The impact of virus infections on pneumonia mortality is complex in adults: a prospective multicentre observational study. BMC Infect Dis. 2017;17:755 pubmed publisher
    ..10, 95% CI 0.01-0.70) but not with chronic respiratory disease. These effects were not affected by age group. The impact of virus infections on pneumonia mortality varies by virus type and comorbidity status in adults. ..
  40. Kumar P, Ram U. Patterns, factors associated and morbidity burden of asthma in India. PLoS ONE. 2017;12:e0185938 pubmed publisher
    ..According to recent WHO report, nearly 235 million people are suffering from asthma leading to 383000 deaths in 2015. The burden of asthma morbidity is higher in developed countries and is increasing in developing countries...
  41. Li G, Xu L, Zhao Y, Li L, Fu J, Zhang Q, et al. Leptin-adiponectin imbalance as a marker of metabolic syndrome among Chinese children and adolescents: The BCAMS study. PLoS ONE. 2017;12:e0186222 pubmed publisher
    ..A total of 3,428 subjects aged 6-18 years were selected from Beijing Child and Adolescent Metabolic Syndrome study. Adipokine leptin and adiponectin were measured using enzyme-linked immunosorbent assay...
  42. Ababu Y, Braka F, Teka A, Getachew K, Tadesse T, Michael Y, et al. Behavioral determinants of immunization service utilization in Ethiopia: a cross-sectional community-based survey. Pan Afr Med J. 2017;27:2 pubmed publisher
    ..The study employed the Modified Steps of Behavioral Change (SBC) Model as a theoretical lens...
  43. Dieye Y, Storey H, Barrett K, Gerth Guyette E, Di Giorgio L, Golden A, et al. Feasibility of utilizing the SD BIOLINE Onchocerciasis IgG4 rapid test in onchocerciasis surveillance in Senegal. PLoS Negl Trop Dis. 2017;11:e0005884 pubmed publisher
    ..This study provides evidence of the feasibility of implementing the Ov16 rapid test in Senegal and may be informative to other country programs transitioning to Ov16 serologic tools...
  44. Rosbrook K, Erythropel H, DeWinter T, Falinski M, O MALLEY S, Krishnan Sarin S, et al. The effect of sucralose on flavor sweetness in electronic cigarettes varies between delivery devices. PLoS ONE. 2017;12:e0185334 pubmed publisher
  45. Michaels J, Chaumillon R, Nguyen Tri D, Watanabe D, Hirsch P, Bellavance F, et al. Driving simulator scenarios and measures to faithfully evaluate risky driving behavior: A comparative study of different driver age groups. PLoS ONE. 2017;12:e0185909 pubmed publisher
    ..Importantly, future research should continue to investigate the predictive utility of perceptual-cognitive tests in the domain of driving risk assessment. ..
  46. Schmeltz M, Gamble J. Risk characterization of hospitalizations for mental illness and/or behavioral disorders with concurrent heat-related illness. PLoS ONE. 2017;12:e0186509 pubmed publisher
    ..Our results suggest that hospitalizations among substance abusers may also be an important risk factor associated with heat morbidity. Improved understanding of these relative risks could help inform future public health strategies. ..
  47. Keller K, Bradley J, Sun Y, Yang Y, Acott T. Tunneling Nanotubes are Novel Cellular Structures That Communicate Signals Between Trabecular Meshwork Cells. Invest Ophthalmol Vis Sci. 2017;58:5298-5307 pubmed publisher
    ..Recently, specialized filopodia called tunneling nanotubes (TNTs) have been described, which communicate molecular signals and organelles directly between cells. Here, we investigate TNT formation by TM cells...
  48. Mosakhani N, Missiry M, Vakkila E, Knuutila S, Vakkila J. Low Expression of miR-18a as a Characteristic of Pediatric Acute Lymphoblastic Leukemia. J Pediatr Hematol Oncol. 2017;39:585-588 pubmed publisher
    ..Pediatric and adult patients with ALL have remarkably similar patterns of immune-cell-associated miRNAs in their bone marrow at diagnosis. However, the low expression of miR-18a in pediatric ALL is interesting and demands further study. ..
  49. Hardell L, Carlberg M. Mobile phones, cordless phones and rates of brain tumors in different age groups in the Swedish National Inpatient Register and the Swedish Cancer Register during 1998-2015. PLoS ONE. 2017;12:e0185461 pubmed publisher
    ..The real incidence would be higher. Thus, incidence trends based on the Cancer Register should be used with caution. Use of wireless phones should be considered in relation to the change of incidence rates...
  50. Zaremski J, McClelland J, Vincent H, Horodyski M. Trends in Sports-Related Elbow Ulnar Collateral Ligament Injuries. Orthop J Sports Med. 2017;5:2325967117731296 pubmed publisher
    Elbow ulnar collateral ligament (UCL) injuries are common, particularly in adolescent athletes playing overhead sports...
  51. Dimopoulou D, Trachana M, Pratsidou Gertsi P, Sidiropoulos P, Kanakoudi Tsakalidou F, Dimitroulas T, et al. Predictors and long-term outcome in Greek adults with juvenile idiopathic arthritis: a 17-year continuous follow-up study. Rheumatology (Oxford). 2017;56:1928-1938 pubmed publisher
    ..To describe the disease characteristics, continuous course and long-term outcome and to evaluate predictors of outcome in JIA in Greece...
  52. Momin B, Pinheiro P, Carreira H, Li C, Weir H. Liver cancer survival in the United States by race and stage (2001-2009): Findings from the CONCORD-2 study. Cancer. 2017;123 Suppl 24:5059-5078 pubmed publisher
    ..The number of Americans who are diagnosed with and die of liver cancer has been rising slowly each year. Using data from the CONCORD-2 study, this study examined population-based survival by state, race, and stage at diagnosis...
  53. Latham S, Hughes E, Budgen B, Mechinaud F, Crock C, Ekert H, et al. Sources of error in measurement of minimal residual disease in childhood acute lymphoblastic leukemia. PLoS ONE. 2017;12:e0185556 pubmed publisher
    ..The level of minimal residual disease (MRD) in marrow predicts outcome and guides treatment in childhood acute lymphoblastic leukemia (ALL) but accurate prediction depends on accurate measurement...