toxoplasmosis

Summary

Summary: The acquired form of infection by Toxoplasma gondii in animals and man.

Top Publications

  1. Andrade W, Souza M, Ramos Martínez E, Nagpal K, Dutra M, Melo M, et al. Combined action of nucleic acid-sensing Toll-like receptors and TLR11/TLR12 heterodimers imparts resistance to Toxoplasma gondii in mice. Cell Host Microbe. 2013;13:42-53 pubmed publisher
    ..single or even the triple NAS-TLR-deficient animals recapitulated the 3d susceptible phenotype to experimental toxoplasmosis. Investigating this further, we found that while parasite RNA and DNA activate innate immune responses via ..
  2. Vanagas L, Jeffers V, Bogado S, Dalmasso M, Sullivan W, Angel S. Toxoplasma histone acetylation remodelers as novel drug targets. Expert Rev Anti Infect Ther. 2012;10:1189-201 pubmed publisher
    ..Finally, the authors discuss the distinct possibility that the unique nucleosome composition of Toxoplasma, which harbors a nonconserved H2Bv variant histone, might be targeted in novel therapeutics directed against this parasite. ..
  3. Dupont C, Christian D, Hunter C. Immune response and immunopathology during toxoplasmosis. Semin Immunopathol. 2012;34:793-813 pubmed publisher
    ..we will review current knowledge of the innate and adaptive immune responses required for resistance to toxoplasmosis, the events that lead to the development of immunopathology, and the natural regulatory mechanisms that limit ..
  4. Kravets E, Degrandi D, Weidtkamp Peters S, Ries B, Konermann C, Felekyan S, et al. The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii. J Biol Chem. 2012;287:27452-66 pubmed publisher
    ..Ultimately, we show that the GTPase domain regulates efficient recruitment to T. gondii in response to IFN-?. ..
  5. Jones J, Dubey J. Foodborne toxoplasmosis. Clin Infect Dis. 2012;55:845-51 pubmed publisher
    b>Toxoplasmosis can be due to congenital infection or acquired infection after birth and is one of the leading illnesses associated with foodborne hospitalizations and deaths...
  6. Amerizadeh A, Idris Z, Khoo B, Kotresha D, Yunus M, Karim I, et al. Identification of Toxoplasma gondii in-vivo induced antigens by cDNA library immunoscreening with chronic toxoplasmosis sera. Microb Pathog. 2013;54:60-6 pubmed publisher
    b>Toxoplasmosis is an infection caused by the parasite Toxoplasma gondii. Chronically-infected individuals with a compromised immune system are at risk for reactivation of the disease...
  7. Morris J, Greenspan A, Howell K, Gargano L, Mitchell J, Jones J, et al. Southeastern Center for Emerging Biologic Threats tabletop exercise: foodborne toxoplasmosis outbreak on college campuses. Biosecur Bioterror. 2012;10:89-97 pubmed publisher
  8. Amerizadeh A, Khoo B, Teh A, Golkar M, Abdul Karim I, Osman S, et al. Identification and real-time expression analysis of selected Toxoplasma gondii in-vivo induced antigens recognized by IgG and IgM in sera of acute toxoplasmosis patients. BMC Infect Dis. 2013;13:287 pubmed publisher
    ..In this study in-vivo induced antigens of this parasite was investigated using in-vivo induced antigen technology (IVIAT) and pooled sera from patients with serological evidence of acute infection...
  9. Zemene E, Yewhalaw D, Abera S, Belay T, Samuel A, Zeynudin A. Seroprevalence of Toxoplasma gondii and associated risk factors among pregnant women in Jimma town, Southwestern Ethiopia. BMC Infect Dis. 2012;12:337 pubmed publisher
    b>Toxoplasmosis is a common parasitic infection caused by an obligate intracellular protozoan, Toxoplasma gondii...

More Information

Publications79

  1. Flegr J, Lenochova P, Hodny Z, Vondrová M. Fatal attraction phenomenon in humans: cat odour attractiveness increased for toxoplasma-infected men while decreased for infected women. PLoS Negl Trop Dis. 2011;5:e1389 pubmed publisher
    Latent toxoplasmosis, a lifelong infection with the protozoan Toxoplasma gondii, has cumulative effects on the behaviour of hosts, including humans...
  2. Galvan Ramirez M, Troyo R, Roman S, Calvillo Sanchez C, Bernal Redondo R. A systematic review and meta-analysis of Toxoplasma gondii infection among the Mexican population. Parasit Vectors. 2012;5:271 pubmed publisher
    b>Toxoplasmosis is a disease caused by Toxoplasma gondii and at least one-third of the world's population has detectable T. gondii antibodies. The seroprevalence of T.gondii ranges from 15% to 50% among the Mexican general population...
  3. Liu Q, Singla L, Zhou H. Vaccines against Toxoplasma gondii: status, challenges and future directions. Hum Vaccin Immunother. 2012;8:1305-8 pubmed publisher
    ..Effective vaccines may contribute toward preventing and controlling the spread of toxoplasmosis. The present communication addresses the current status of development of vaccines against T. gondii...
  4. Wallon M, Peyron F, Cornu C, Vinault S, Abrahamowicz M, Kopp C, et al. Congenital toxoplasma infection: monthly prenatal screening decreases transmission rate and improves clinical outcome at age 3 years. Clin Infect Dis. 2013;56:1223-31 pubmed publisher
    ..with acute Toxoplasma infection in Lyon (France) from 1987 to 2008 and assessed how the risks of congenital toxoplasmosis and of clinical signs at age 3 years vary depending on GA at the time of maternal infection...
  5. Flatt A, Shetty N. Seroprevalence and risk factors for toxoplasmosis among antenatal women in London: a re-examination of risk in an ethnically diverse population. Eur J Public Health. 2013;23:648-52 pubmed publisher
    ..The objective of our study was to evaluate seroprevalence of and analyse risk factors for toxoplasmosis in antenatal women from 2006 to 2008 in an ethnically diverse population of Central London to re-examine the ..
  6. Hunter C, Sibley L. Modulation of innate immunity by Toxoplasma gondii virulence effectors. Nat Rev Microbiol. 2012;10:766-78 pubmed publisher
    ..Here, we review recent advances that illustrate how these virulence factors disarm innate immunity and promote survival of the parasite. ..
  7. Lang C, Hildebrandt A, Brand F, Opitz L, Dihazi H, Lüder C. Impaired chromatin remodelling at STAT1-regulated promoters leads to global unresponsiveness of Toxoplasma gondii-infected macrophages to IFN-?. PLoS Pathog. 2012;8:e1002483 pubmed publisher
    ..Taken together, these results indicate that Toxoplasma-infected M? are unable to respond to IFN-? due to disturbed chromatin remodelling, but can be rescued using histone deacetylase inhibitors. ..
  8. Gebremedhin E, Abebe A, Tessema T, Tullu K, Medhin G, Vitale M, et al. Seroepidemiology of Toxoplasma gondii infection in women of child-bearing age in central Ethiopia. BMC Infect Dis. 2013;13:101 pubmed publisher
    ..Prevalence and risk factors of toxoplasmosis in women of child-bearing age in Ethiopia are unknown...
  9. Dubey J, Ferreira L, Martins J, McLeod R. Oral oocyst-induced mouse model of toxoplasmosis: effect of infection with Toxoplasma gondii strains of different genotypes, dose, and mouse strains (transgenic, out-bred, in-bred) on pathogenesis and mortality. Parasitology. 2012;139:1-13 pubmed publisher
    ..In the present study, pathogenesis of toxoplasmosis was studied in mice of different strains, including Human Leukocyte Antigen (HLA) transgenic mice infected ..
  10. Nance J, Vannella K, Worth D, David C, Carter D, Noor S, et al. Chitinase dependent control of protozoan cyst burden in the brain. PLoS Pathog. 2012;8:e1002990 pubmed publisher
    ..These data demonstrate chitinase activity in the brain in response to a protozoan pathogen and provide a novel mechanism to facilitate cyst clearance during chronic infections...
  11. Boughattas S, Abdallah R, Siala E, Aoun K, Bouratbine A. An atypical strain associated with congenital toxoplasmosis in Tunisia. New Microbiol. 2011;34:413-6 pubmed
    We report the identification and typing of a congenital toxoplasmosis case in a diabetic pregnant young woman living in Tunis...
  12. Fritz H, Bowyer P, Bogyo M, Conrad P, Boothroyd J. Proteomic analysis of fractionated Toxoplasma oocysts reveals clues to their environmental resistance. PLoS ONE. 2012;7:e29955 pubmed publisher
    ..The latter are known from other systems to be key to enabling survival against desiccation...
  13. Sagel U, Kramer A, Mikolajczyk R. Incidence of maternal Toxoplasma infections in pregnancy in Upper Austria, 2000-2007. BMC Infect Dis. 2011;11:348 pubmed publisher
    Despite three decades of prenatal screening program for toxoplasmosis in Austria, population-based estimates for the incidence of maternal infections with Toxoplasma gondii during pregnancy are lacking...
  14. Khammari I, Saghrouni F, Yaacoub A, Gaied Meksi S, Ach H, Garma L, et al. IgG western blot for confirmatory diagnosis of equivocal cases of toxoplasmosis by EIA-IgG and fluorescent antibody test. Korean J Parasitol. 2013;51:485-8 pubmed publisher
    The performance values of available techniques used in serodiagnosis of toxoplasmosis are satisfactory but they raise problems of equivocal and discordant results for very low IgG titers...
  15. Zhang N, Chen J, Wang M, Petersen E, Zhu X. Vaccines against Toxoplasma gondii: new developments and perspectives. Expert Rev Vaccines. 2013;12:1287-99 pubmed publisher
    b>Toxoplasmosis caused by the protozoan Toxoplasma gondii is a major public health problem, infecting one-third of the world human beings, and leads to abortion in domestic animals...
  16. Arias I, Sorlozano A, Villegas E, De Dios Luna J, McKenney K, Cervilla J, et al. Infectious agents associated with schizophrenia: a meta-analysis. Schizophr Res. 2012;136:128-36 pubmed publisher
    ..001), Chlamydophila psittaci (OR=29.05; CI 95%: 8.91-94.70; p<0.001) and Toxoplasma gondii (OR=2.70; CI 95%: 1.34-4.42; p=0.005). The implications of these findings are discussed and further research options are also explicated...
  17. Ferezin R, Bertolini D, Demarchi I. [Prevalence of positive sorology for HIV, hepatitis B, toxoplasmosis and rubella in pregnant women from the northwestern region of the state of Paraná]. Rev Bras Ginecol Obstet. 2013;35:66-70 pubmed
    To ascertain the seroprevalence of human immunodeficiency virus (HIV), hepatitis B (HBV), toxoplasmosis and rubella infections in pregnant women in northwestern Paraná.
  18. Craven M, Egan C, Dowd S, McDonough S, Dogan B, Denkers E, et al. Inflammation drives dysbiosis and bacterial invasion in murine models of ileal Crohn's disease. PLoS ONE. 2012;7:e41594 pubmed publisher
    ..We sought to examine the dynamics of the relationship between inflammation, the ileal microbiome, and host genetics in murine models of ileitis...
  19. Yang Z, Cho P, Ahn S, Ahn H, Kim T, Chong C, et al. A surge in the seroprevalence of toxoplasmosis among the residents of islands in Gangwha-gun, Incheon, Korea. Korean J Parasitol. 2012;50:191-7 pubmed publisher
    ..5%), and maintained or increased in 94 persons (14.2%). This rapid increase in the prevalence of toxoplasmosis in Gangwha islands may be due to in part peculiar changes in the toxoplasmic environment of the islands and ..
  20. Sun X, Ji Y, Elashram S, Lu Z, Liu X, Suo X, et al. Identification of antigenic proteins of Toxoplasma gondii RH strain recognized by human immunoglobulin G using immunoproteomics. J Proteomics. 2012;77:423-32 pubmed publisher
    ..had a broad reactivity with Toxoplasma-positive sera, indicating their potential as diagnostic markers for toxoplasmosis. Each of several combinations of the identified proteins offered 100% detection of Toxoplasma infections of ..
  21. Rodriguez J, Szajnman S. New antibacterials for the treatment of toxoplasmosis; a patent review. Expert Opin Ther Pat. 2012;22:311-33 pubmed publisher
    Toxoplasma gondii is an opportunistic protozoan parasite responsible for toxoplasmosis. T. gondii is able to infect a wide range of hosts, particularly humans and warm-blooded animals...
  22. Holec Gasior L. Toxoplasma gondii recombinant antigens as tools for serodiagnosis of human toxoplasmosis: current status of studies. Clin Vaccine Immunol. 2013;20:1343-51 pubmed publisher
    Toxoplasma gondii is a parasitic protozoan which is the cause of toxoplasmosis. Although human toxoplasmosis in healthy adults is usually asymptomatic, serious disease can occur in the case of congenital infections and immunocompromised ..
  23. Torrey E, Bartko J, Yolken R. Toxoplasma gondii and other risk factors for schizophrenia: an update. Schizophr Bull. 2012;38:642-7 pubmed publisher
    ..01), specific genetic polymorphisms (OR 1.09-1.24; 95% CI 1.06-1.45), birth seasonality (OR 1.07-1.95; 95% CI 1.05-2.91), maternal exposure to influenza (RR 1.05; 95% CI 0.98-1.12), or prenatal stress (RR 0.98-1.00; 95% CI 0.85-1.16)...
  24. Dziadek B, Gatkowska J, Grzybowski M, Dziadek J, Dzitko K, Dlugonska H. Toxoplasma gondii: the vaccine potential of three trivalent antigen-cocktails composed of recombinant ROP2, ROP4, GRA4 and SAG1 proteins against chronic toxoplasmosis in BALB/c mice. Exp Parasitol. 2012;131:133-8 pubmed publisher
    b>Toxoplasmosis is one of the world's most widespread zoonoses caused by protozoan parasite Toxoplasma gondii...
  25. Robert Gangneux F, Dardé M. Epidemiology of and diagnostic strategies for toxoplasmosis. Clin Microbiol Rev. 2012;25:264-96 pubmed publisher
    ..In particular, we provide critical information on diagnostic methods according to the patient's background and discuss the implementation of screening tools for congenital toxoplasmosis according to health policies.
  26. Linguissi L, Nagalo B, Bisseye C, Kagoné T, Sanou M, Tao I, et al. Seroprevalence of toxoplasmosis and rubella in pregnant women attending antenatal private clinic at Ouagadougou, Burkina Faso. Asian Pac J Trop Med. 2012;5:810-3 pubmed publisher
    To evaluate the prevalence of toxoplasmosis and rubella among pregnant women at Ouagadougou in Burkina Faso.
  27. Yuan Z, Ren D, Zhou D, Zhang X, Petersen E, Li X, et al. Evaluation of protective effect of pVAX-TgMIC13 plasmid against acute and chronic Toxoplasma gondii infection in a murine model. Vaccine. 2013;31:3135-9 pubmed publisher
    ..gondii RH strain and cysts of the T. gondii PRU strain, respectively, demonstrating that T. gondii MIC13 is a potential vaccine candidate, worth being included in future vaccine development against acute and chronic T. gondii infection. ..
  28. Holec Gasior L, Ferra B, Drapała D, Lautenbach D, Kur J. A new MIC1-MAG1 recombinant chimeric antigen can be used instead of the Toxoplasma gondii lysate antigen in serodiagnosis of human toxoplasmosis. Clin Vaccine Immunol. 2012;19:57-63 pubmed publisher
    ..1)-MAG1 (matrix antigen 1) Toxoplasma gondii recombinant chimeric antigen for the serodiagnosis of human toxoplasmosis for the first time...
  29. Fabiani S, Pinto B, Bruschi F. Toxoplasmosis and neuropsychiatric diseases: can serological studies establish a clear relationship?. Neurol Sci. 2013;34:417-25 pubmed publisher
    b>Toxoplasmosis is a widespread infection, with clinical spectrum ranging from a completely asymptomatic infection to multi-organ involvement...
  30. Walle F, Kebede N, Tsegaye A, Kassa T. Seroprevalence and risk factors for Toxoplasmosis in HIV infected and non-infected individuals in Bahir Dar, Northwest Ethiopia. Parasit Vectors. 2013;6:15 pubmed publisher
    b>Toxoplasmosis, a zoonotic disease distributed worldwide, is an infection caused by the ubiquitous obligatory intracellular coccidian protozoan organism, Toxoplasma gondii...
  31. Zhao G, Zhou A, Lv G, Meng M, Sun M, Bai Y, et al. Toxoplasma gondii cathepsin proteases are undeveloped prominent vaccine antigens against toxoplasmosis. BMC Infect Dis. 2013;13:207 pubmed publisher
    ..Both of these proteases are potential therapeutic targets in T. gondii. The aim of this study was to investigate TgCPB and TgCPL for their potential as DNA vaccines against T. gondii...
  32. Dubey J, Tiao N, Gebreyes W, Jones J. A review of toxoplasmosis in humans and animals in Ethiopia. Epidemiol Infect. 2012;140:1935-8 pubmed
    b>Toxoplasmosis caused by the protozoan parasite, Toxoplasma gondii, is a worldwide zoonosis. In this paper published information on toxoplasmosis in humans and other animals in Ethiopia is reviewed...
  33. Chew W, Segarra I, Ambu S, Mak J. Significant reduction of brain cysts caused by Toxoplasma gondii after treatment with spiramycin coadministered with metronidazole in a mouse model of chronic toxoplasmosis. Antimicrob Agents Chemother. 2012;56:1762-8 pubmed publisher
    ..Male BALB/c mice were fed 1,000 tachyzoites orally to develop chronic toxoplasmosis. Four weeks later, infected mice underwent different treatments: (i) infected untreated mice (n = 9), which ..
  34. Fernàndez Sabé N, Cervera C, Farinas M, Bodro M, Munoz P, Gurgui M, et al. Risk factors, clinical features, and outcomes of toxoplasmosis in solid-organ transplant recipients: a matched case-control study. Clin Infect Dis. 2012;54:355-61 pubmed publisher
    Solid-organ transplant (SOT) recipients are considered to be at increased risk for toxoplasmosis. However, risk factors for this infection have not been assessed...
  35. Vittecoq M, Elguero E, Lafferty K, Roche B, Brodeur J, Gauthier Clerc M, et al. Brain cancer mortality rates increase with Toxoplasma gondii seroprevalence in France. Infect Genet Evol. 2012;12:496-8 pubmed publisher
    ..While this novel evidence of a significant statistical association between T. gondii infection and brain cancer does not demonstrate causation, these results suggest that investigations at the scale of the individual are merited...
  36. Santana S, Silva D, Vaz L, Pirovani C, Barros G, Lemos E, et al. Analysis of IgG subclasses (IgG1 and IgG3) to recombinant SAG2A protein from Toxoplasma gondii in sequential serum samples from patients with toxoplasmosis. Immunol Lett. 2012;143:193-201 pubmed publisher
    ..comparatively to soluble Toxoplasma antigen (STAg) by ELISA in sequential serum samples of patients with toxoplasmosis up to 12 months of illness onset...
  37. Reid A, Vermont S, Cotton J, Harris D, Hill Cawthorne G, Könen Waisman S, et al. Comparative genomics of the apicomplexan parasites Toxoplasma gondii and Neospora caninum: Coccidia differing in host range and transmission strategy. PLoS Pathog. 2012;8:e1002567 pubmed publisher
    ..caninum may be associated with the evolution of reduced virulence in this species...
  38. Doggett J, Nilsen A, Forquer I, Wegmann K, Jones Brando L, Yolken R, et al. Endochin-like quinolones are highly efficacious against acute and latent experimental toxoplasmosis. Proc Natl Acad Sci U S A. 2012;109:15936-41 pubmed
    ..gondii growth in vitro and is effective against acute and latent toxoplasmosis in mice. We screened 50 ELQs against T...
  39. Torrey E, Yolken R. Toxoplasma oocysts as a public health problem. Trends Parasitol. 2013;29:380-4 pubmed publisher
    ..The proper disposal of cat litter, keeping cats indoors, reducing the feral cat population, and protecting the play areas of children might potentially reduce the oocyst burden. ..
  40. Cebrian I, Visentin G, Blanchard N, Jouve M, Bobard A, Moita C, et al. Sec22b regulates phagosomal maturation and antigen crosspresentation by dendritic cells. Cell. 2011;147:1355-68 pubmed publisher
    ..Our findings provide insight into an intracellular traffic pathway required for crosspresentation and show that Sec22b-dependent recruitment of ER proteins to Phgs critically influences phagosomal functions in DCs...
  41. Ekman C, Chiossi M, Meireles L, Andrade Junior H, Figueiredo W, Marciano M, et al. Case-control study of an outbreak of acute toxoplasmosis in an industrial plant in the state of São Paulo, Brazil. Rev Inst Med Trop Sao Paulo. 2012;54:239-44 pubmed
    ..We described an outbreak of nine clustered cases of acute illness resembling acute toxoplasmosis in an industrial plant with 2300 employees...
  42. Zhou H, Min J, Zhao Q, Gu Q, Cong H, Li Y, et al. Protective immune response against Toxoplasma gondii elicited by a recombinant DNA vaccine with a novel genetic adjuvant. Vaccine. 2012;30:1800-6 pubmed publisher
    ..of IFN-? and low levels of IL-4 or IL-10 in BALB/c mice, and partial protection against the acute phase of toxoplasmosis as compared to pSAG1, pGRA2 and controls...
  43. Rahbari A, Keshavarz H, Shojaee S, Mohebali M, Rezaeian M. IgG avidity ELISA test for diagnosis of acute toxoplasmosis in humans. Korean J Parasitol. 2012;50:99-102 pubmed publisher
    ..2), then the avidity index (AI) was calculated. Sixteen out of 18 (88.9%) sera with acute toxoplasmosis showed low avidity levels (AI ? 50), and 76 out of 82 (92...
  44. Saadatnia G, Golkar M. A review on human toxoplasmosis. Scand J Infect Dis. 2012;44:805-14 pubmed publisher
    b>Toxoplasmosis is a worldwide infection caused by the intracellular parasite Toxoplasma gondii. At least a third of the world human population are infected with the parasite, making it one of the most successful parasitic infections...
  45. Neves E, Curi A, Albuquerque M, Palhano Silva C, Silva L, Bueno W, et al. Genetic polymorphism for IFN? +874T/A in patients with acute toxoplasmosis. Rev Soc Bras Med Trop. 2012;45:757-60 pubmed
    ..This study aimed to evaluate the association of IFN?+874T/A SNP with duration of disease, morbidity, and development of retinochoroiditis in acute toxoplasmosis.
  46. Joshi P, Lele V, Mahajan P. Lymphadenopathy resulting from acute toxoplasmosis mimicking relapse of non-Hodgkin's lymphoma on fluorodeoxyglucose positron emission tomography/computed tomography. J Cancer Res Ther. 2012;8:126-8 pubmed publisher
    ..FDG) accumulation in cervical, supraclavicular and axillary lymph nodes resulting from acute toxoplasmosis. A 50-year-old Indian female with history of non-Hodgkin's lymphoma (NHL) of left breast, postchemotherapy ..
  47. Soares J, Carvalho S, Caldeira A. Profile of pregnant women and children treated at a reference center for congenital toxoplasmosis in the northern state of Minas Gerais, Brazil. Rev Soc Bras Med Trop. 2012;45:55-9 pubmed
    To describe the clinical and epidemiological profile of pregnant women and children treated at a reference outpatient clinic for congenital toxoplasmosis.
  48. Pearce B, Kruszon Moran D, Jones J. The relationship between Toxoplasma gondii infection and mood disorders in the third National Health and Nutrition Survey. Biol Psychiatry. 2012;72:290-5 pubmed publisher
    ..4; 95% CI: 1.2-4.8; p < .05). In a population-based sample, T. gondii seroprevalence is not elevated in unipolar mood disorders but is higher in a subset of respondents with a history of bipolar disorder type 1. ..
  49. Robbins J, Zeldovich V, Poukchanski A, Boothroyd J, Bakardjiev A. Tissue barriers of the human placenta to infection with Toxoplasma gondii. Infect Immun. 2012;80:418-28 pubmed publisher
  50. Dubey J, Lago E, Gennari S, Su C, Jones J. Toxoplasmosis in humans and animals in Brazil: high prevalence, high burden of disease, and epidemiology. Parasitology. 2012;139:1375-424 pubmed publisher
    ..The burden of clinical toxoplasmosis in humans is considered to be very high...
  51. Alvarado Esquivel C, Torres Castorena A, Liesenfeld O, Estrada Martínez S, Urbina Álvarez J. High seroprevalence of Toxoplasma gondii infection in a subset of Mexican patients with work accidents and low socioeconomic status. Parasit Vectors. 2012;5:13 pubmed publisher
    ..Socio-demographic, work, clinical and behavioral characteristics from each worker were obtained...
  52. Alvarado Esquivel C, Estrada Martínez S, García López C, Rojas Rivera A, Sifuentes Alvarez A, Liesenfeld O. Seroepidemiology of Toxoplasma gondii infection in Tepehuanos in Durango, Mexico. Vector Borne Zoonotic Dis. 2012;12:138-42 pubmed publisher
    ..Toxoplasma may be impacting the health of Tepehuanos. This is the first report of T. gondii infection in Tepehuanos, and the results should prove useful for the design of preventive measures...
  53. Robert Gangneux F, Murat J, Fricker Hidalgo H, Brenier Pinchart M, Gangneux J, Pelloux H. The placenta: a main role in congenital toxoplasmosis?. Trends Parasitol. 2011;27:530-6 pubmed publisher
    Systemic infections, such as toxoplasmosis, acquired during pregnancy can lead to placental infection and have profound effects on the mother-to-child relationship and the success of pregnancy...
  54. Sullivan W, Jeffers V. Mechanisms of Toxoplasma gondii persistence and latency. FEMS Microbiol Rev. 2012;36:717-33 pubmed publisher
    ..Bradyzoite tissue cysts can cause reactivated toxoplasmosis if host immunity becomes impaired...
  55. Murakami Y, Hoshi M, Hara A, Takemura M, Arioka Y, Yamamoto Y, et al. Inhibition of increased indoleamine 2,3-dioxygenase activity attenuates Toxoplasma gondii replication in the lung during acute infection. Cytokine. 2012;59:245-51 pubmed publisher
    ..Inhibition of the IDO activity or the elimination of IDO's substrate may be an effective therapy against microbial diseases...
  56. Sakikawa M, Noda S, Hanaoka M, Nakayama H, Hojo S, Kakinoki S, et al. Anti-Toxoplasma antibody prevalence, primary infection rate, and risk factors in a study of toxoplasmosis in 4,466 pregnant women in Japan. Clin Vaccine Immunol. 2012;19:365-7 pubmed publisher
    b>Toxoplasmosis is a zoonosis caused by infection with Toxoplasma gondii and is prevalent worldwide under various climatic conditions...
  57. Berenreiterová M, Flegr J, Kubena A, Nemec P. The distribution of Toxoplasma gondii cysts in the brain of a mouse with latent toxoplasmosis: implications for the behavioral manipulation hypothesis. PLoS ONE. 2011;6:e28925 pubmed publisher
    ..Paradoxically, the distribution of the parasite in the brain has received only scant attention...
  58. Gomez Marin J, de la Torre A, Barrios P, Cardona N, Alvarez C, Herrera C. Toxoplasmosis in military personnel involved in jungle operations. Acta Trop. 2012;122:46-51 pubmed publisher
    ..However, no knowledge exists about toxoplasmosis, an emergent disease in military personnel...
  59. Dubremetz J, Lebrun M. Virulence factors of Toxoplasma gondii. Microbes Infect. 2012;14:1403-10 pubmed publisher
    ..It is essentially defined in the mouse and little is known concerning human infection. The genetic dependence of virulence is a growing field, benefiting from the recent development of research of the population structure of T. gondii...
  60. Hao Y. [Difference of Toxoplasma gondii infection status between urban and rural childbearing age women visiting to hospitals in southwest region of Shandong Province]. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2013;25:113-4 pubmed
    ..05 for all). These results suggested that the corresponding prevention and control measures of toxoplasmosis should be formulated on the basis of different areas and occupations.
  61. Doudou Y, Renaud P, Coralie L, Jacqueline F, Hypolite S, Hypolite M, et al. Toxoplasmosis among pregnant women: high seroprevalence and risk factors in Kinshasa, Democratic Republic of Congo. Asian Pac J Trop Biomed. 2014;4:69-74 pubmed publisher
    To determine the seroprevalence of toxoplasmosis in pregnant women, as well as the proportion of acutely infected and risk factors in the Democratic Republic of Congo.
  62. Xavier G, Cademartori B, Cunha Filho N, Farias N. Evaluation of seroepidemiological toxoplasmosis in HIV/AIDS patients in the south of Brazil. Rev Inst Med Trop Sao Paulo. 2013;55:25-30 pubmed
    b>Toxoplasmosis is considered one of the opportunistic infections for individuals with the Acquired Immunodeficiency Syndrome (AIDS), and is also a major cause of morbidity and mortality...
  63. Kannangai R, Sachithanandham J, Mahadevan A, Abraham A, Sridharan G, Desai A, et al. Association of neurotropic viruses in HIV-infected individuals who died of secondary complications of tuberculosis, cryptococcosis, or toxoplasmosis in South India. J Clin Microbiol. 2013;51:1022-5 pubmed publisher
    ..JCV was detectable in the CSF of 62% of cases and in 42% of brain tissues, with higher loads in progressive multifocal leukoencephalopathy (PML) (P < 0.05)...
  64. Wong W, Upton A, Thomas M. Neuropsychiatric symptoms are common in immunocompetent adult patients with Toxoplasma gondii acute lymphadenitis. Scand J Infect Dis. 2013;45:357-61 pubmed publisher
    Chronic toxoplasmosis has been shown to be strongly associated with a range of neuropsychiatric effects including schizophrenia and suicide...
  65. Hill D, Dubey J. Toxoplasma gondii prevalence in farm animals in the United States. Int J Parasitol. 2013;43:107-13 pubmed publisher
    b>Toxoplasmosis, caused by Toxoplasma gondii, is one of the most common parasitic infections of humans and other warmblooded animals. It has been found worldwide and nearly one-third of humans have been exposed to the parasite...
  66. Yamamoto M, Okuyama M, Ma J, Kimura T, Kamiyama N, Saiga H, et al. A cluster of interferon-?-inducible p65 GTPases plays a critical role in host defense against Toxoplasma gondii. Immunity. 2012;37:302-13 pubmed
    ..gondii in Gbp(chr3)-deleted cells. Our results suggest that Gbp(chr3) play a pivotal role in anti-T. gondii host defense by controlling IFN-?-mediated Irgb6-dependent cellular innate immunity...
  67. Niedelman W, Gold D, Rosowski E, Sprokholt J, Lim D, Farid Arenas A, et al. The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response. PLoS Pathog. 2012;8:e1002784 pubmed publisher
    ..These findings suggest that ROP18 and ROP5 have specifically evolved to block the IRGs and are unlikely to have effects in species that do not have the IRG system, such as humans...
  68. Fonseca A, Silva R, Fux B, Madureira A, Sousa F, Margonari C. Epidemiologic aspects of toxoplasmosis and evaluation of its seroprevalence in pregnant women. Rev Soc Bras Med Trop. 2012;45:357-64 pubmed
    The aim of the present study was to analyze the exposure to risk factors for toxoplasmosis disease and the level of knowledge in pregnant women who were treated by the Public Health Care System (SUS) from October 2007 to September 2008 ..
  69. Bittencourt L, Lopes Mori F, Mitsuka Breganó R, Valentim Zabott M, Freire R, Pinto S, et al. [Seroepidemiology of toxoplasmosis in pregnant women since the implementation of the Surveillance Program of Toxoplasmosis Acquired in Pregnancy and Congenital in the western region of Paraná, Brazil]. Rev Bras Ginecol Obstet. 2012;34:63-8 pubmed
    To evaluate the susceptibility to toxoplasmosis in pregnant women in the public health service from two cities in the western region of Paraná, Brazil.
  70. Alvarado Esquivel C, Estrada Martínez S, Liesenfeld O. Toxoplasma gondii infection in workers occupationally exposed to unwashed raw fruits and vegetables: a case control seroprevalence study. Parasit Vectors. 2011;4:235 pubmed publisher
    ..Through a case control seroprevalence study, we sought to determine the association of Toxoplasma gondii infection with occupational exposure to unwashed raw fruits and vegetables...