strongyloidiasis

Summary

Summary: Infection with nematodes of the genus STRONGYLOIDES. The presence of larvae may produce pneumonitis and the presence of adult worms in the intestine could lead to moderate to severe diarrhea.

Top Publications

  1. Roxby A, Gottlieb G, Limaye A. Strongyloidiasis in transplant patients. Clin Infect Dis. 2009;49:1411-23 pubmed publisher
    ..but physicians in the United States often miss opportunities to identify patients with chronic strongyloidiasis. Screening tests have limitations, and clinical suspicion remains an important component of the evaluation ..
  2. Croker C, Reporter R, Redelings M, Mascola L. Strongyloidiasis-related deaths in the United States, 1991-2006. Am J Trop Med Hyg. 2010;83:422-6 pubmed publisher
    The objective of this study was to 1) assess the incidence of strongyloidiasis in the United States, 2) evaluate demographic and regional associations, and 3) identify comorbid conditions as risk factors for death...
  3. Suarez A, Sánchez C. [Strongyloides stercoralis: histopathological findings of duodenal mucosa (1999-2005)]. Rev Gastroenterol Peru. 2006;26:44-8 pubmed
    b>Strongyloidiasis is a parasitosis, which endoscopic and histopathologic presentations are very varied. It is mainly found in the duodenum, where the larva matures into adult female and induces varied patterns of inflammatory reactions...
  4. Aregawi D, Lopez D, Wick M, Scheld W, Schiff D. Disseminated strongyloidiasis complicating glioblastoma therapy: a case report. J Neurooncol. 2009;94:439-43 pubmed publisher
    ..Here we report an immunocompromised patient with glioblastoma who developed disseminated strongyloidiasis 6 weeks after completion of standard radiotherapy and concurrent temozolomide chemotherapy...
  5. Basuni M, Muhi J, Othman N, Verweij J, Ahmad M, Miswan N, et al. A pentaplex real-time polymerase chain reaction assay for detection of four species of soil-transmitted helminths. Am J Trop Med Hyg. 2011;84:338-43 pubmed publisher
    ..05). In conclusion, the real-time PCR assay described in this study provides a specific and sensitive diagnostic tool for the detection of these four helminth species in epidemiological studies and monitoring of treatment programs...
  6. Krishnamurthy R, Dincer H, Whittemore D. Strongyloides stercoralis hyperinfection in a patient with rheumatoid arthritis after anti-TNF-alpha therapy. J Clin Rheumatol. 2007;13:150-2 pubmed
    b>Strongyloidiasis is epidemic in tropical and subtropical regions where the regional prevalence may exceed 25%. In the United States, highest infection rates are found in immigrants...
  7. Marcos L, Terashima A, DuPont H, Gotuzzo E. Strongyloides hyperinfection syndrome: an emerging global infectious disease. Trans R Soc Trop Med Hyg. 2008;102:314-8 pubmed publisher
    ..HS is an example of an emerging tropical infection migrating to developed countries and requiring greater clinician awareness. ..
  8. Sykes A, McCarthy J. A coproantigen diagnostic test for Strongyloides infection. PLoS Negl Trop Dis. 2011;5:e955 pubmed publisher
    ..These results indicate that diagnosis of human strongyloidiasis by detection of coproantigen is an approach worthy of further development.
  9. Minematsu H, Hokama A, Makishi T, Arakaki K, Kinjo F, Fujita J. Colonoscopic findings and pathologic characteristics of Strongyloides colitis: a case series. Digestion. 2011;83:210-4 pubmed publisher
    b>Strongyloidiasis, which is caused by Strongyloides stercoralis, is one of the prevalent infections in the tropical and subtropical regions worldwide...

More Information

Publications123 found, 100 shown here

  1. Feliciano N, Gonzaga H, Gonçalves Pires M, Gonçalves A, Rodrigues R, Ueta M, et al. Hydrophobic fractions from Strongyloides venezuelensis for use in the human immunodiagnosis of strongyloidiasis. Diagn Microbiol Infect Dis. 2010;67:153-61 pubmed publisher
    ..and aqueous phases of total saline (TS) and alkaline extracts of Strongyloides venezuelensis for human strongyloidiasis immunodiagnosis...
  2. Kosmadakis G, Georgoulias C, Filiopoulos V, Stefanou I, Smirloglou D, Michail S. Lethal Strongyloides stercoralis superinfection in an immunocompromised patient. Ren Fail. 2010;32:750-2 pubmed publisher
    ..A large worm load of Strongyloides stercoralis larvae was identified in the sputum. The patient was treated with thiopental 25 mg/kgBW/12 h through a Levine tube and died 24 h later. ..
  3. Martin S, Cohen P, MacFarlane D, Grossman M. Cutaneous manifestations of Strongyloides stercoralis hyperinfection in an HIV-seropositive patient. Skinmed. 2011;9:199-202 pubmed
    ..These findings confirmed the diagnosis of disseminated strongyloidiasis. On hospital day 35, the patient was doing poorly and was started on thiabendazole (1250 mg twice daily for ..
  4. Galioto A, Hess J, Nolan T, Schad G, Lee J, Abraham D. Role of eosinophils and neutrophils in innate and adaptive protective immunity to larval strongyloides stercoralis in mice. Infect Immun. 2006;74:5730-8 pubmed
    ..stercoralis in mice...
  5. Schär F, Trostdorf U, Giardina F, Khieu V, Muth S, Marti H, et al. Strongyloides stercoralis: Global Distribution and Risk Factors. PLoS Negl Trop Dis. 2013;7:e2288 pubmed publisher
    ..However, current information underscore that S. stercoralis must not be neglected. Further assessments in socio-economic and ecological settings are needed and integration into global helminth control is warranted. ..
  6. Jayaprakash B, Sandhya S, Anithakumari K. Pulmonary strongyloidiasis. J Assoc Physicians India. 2009;57:535-6 pubmed
    ..She had no evidence of immunosuppression and CT chest showed a lesion suspicious of malignancy, sputum cytology showed strongyloides larvae and the patient had complete recovery with treatment. ..
  7. Vandebosch S, Mana F, Goossens A, Urbain D. Strongyloides Stercoralis infection associated with repititive bacterial meningitis and SIADH: a case report. Acta Gastroenterol Belg. 2008;71:413-7 pubmed
    b>Strongyloidiasis is an infection by the intestinal parasite Strongyloides Stercoralis, which usually stays asymptomatic. In some situations a hyperinfection or disseminated disease can occur...
  8. Ratner L, Grant C, ZIMMERMAN B, Fritz J, Weil G, Denes A, et al. Effect of treatment of Strongyloides infection on HTLV-1 expression in a patient with adult T-cell leukemia. Am J Hematol. 2007;82:929-31 pubmed
    ..This case provides support for the hypothesis that Strongyloides is a cofactor for ATLL via T-cell stimulation. ..
  9. Janwan P, Intapan P, Thanchomnang T, Lulitanond V, Anamnart W, Maleewong W. Rapid detection of Opisthorchis viverrini and Strongyloides stercoralis in human fecal samples using a duplex real-time PCR and melting curve analysis. Parasitol Res. 2011;109:1593-601 pubmed publisher
  10. Abraham D, Hess J, Mejia R, Nolan T, Lok J, Lustigman S, et al. Immunization with the recombinant antigen Ss-IR induces protective immunity to infection with Strongyloides stercoralis in mice. Vaccine. 2011;29:8134-40 pubmed publisher
    ..demonstrate that Ss-IR, in combination with alum, induces high levels of protective immunity through an antibody dependent mechanism and may therefore be suitable for further development as a vaccine against human strongyloidiasis.
  11. Inês E, Souza J, Santos R, Souza E, Santos F, Silva M, et al. Efficacy of parasitological methods for the diagnosis of Strongyloides stercoralis and hookworm in faecal specimens. Acta Trop. 2011;120:206-10 pubmed publisher
    ..6%, 28.4% and 23% of samples, respectively when re-examined by the APC. As a definitive diagnosis of strongyloidiasis depends on the microscopic demonstration of parasites, increasing the sensitivity of the detection requires ..
  12. Bisoffi Z, Buonfrate D, Angheben A, Boscolo M, Anselmi M, Marocco S, et al. Randomized clinical trial on ivermectin versus thiabendazole for the treatment of strongyloidiasis. PLoS Negl Trop Dis. 2011;5:e1254 pubmed publisher
    b>Strongyloidiasis may cause a life-threatening disease in immunosuppressed patients. This can only be prevented by effective cure of chronic infections. Direct parasitologic exams are not sensitive enough to prove cure if negative...
  13. N dri K, Kouame K, Sahari R, Hommel D, Hulin A. [Strongyloides stercoralis hyperinfection syndrome with acute meningoencephalitis associated to HTLV-1 and HTLV-2 virus co-infection]. Med Mal Infect. 2008;38:162-4 pubmed publisher
  14. Takashima N, Yazawa S, Ishihara A, Sugimoto S, Shiomi K, Hiromatsu K, et al. [Fulminant strongyloidiasis successfully treated by subcutaneous ivermectin: an autopsy case]. Rinsho Shinkeigaku. 2008;48:30-5 pubmed
    ..man who was a human T-cell leukemia virus type 1 (HTLV-1) carrier, born in Okinawa prefecture where both strongyloidiasis and HTLV-1 are endemic. He presented with fever, headache and urinary retention...
  15. Meamar A, Rezaian M, Mohraz M, Hadighi R, Kia E. Strongyloides stercoralis hyper-infection syndrome in HIV+/AIDS patients in Iran. Parasitol Res. 2007;101:663-5 pubmed
    ..alteration in immune status, can cause a syndrome of severe hyper-infection or potentially fatal disseminated strongyloidiasis. Due to the increasing numbers of immunocompromised patients in Iran, strongyloidiasis is an emerging public ..
  16. Leung V, Al Rawahi G, Grant J, Fleckenstein L, Bowie W. Case report: failure of subcutaneous ivermectin in treating Strongyloides hyperinfection. Am J Trop Med Hyg. 2008;79:853-5 pubmed
    ..We report the first documented total and free levels of subcutaneous ivermectin used for therapy. ..
  17. Gupta S, Jain A, Fanning T, Couriel D, Jimenez C, Eapen G. An unusual cause of alveolar hemorrhage post hematopoietic stem cell transplantation: a case report. BMC Cancer. 2006;6:87 pubmed
    ..Strongyloides stercoralis hyperinfection is an unusual cause of alveolar hemorrhage early after hematopoietic stem cell transplant with very high mortality. ..
  18. Al Hasan M, McCormick M, Ribes J. Invasive enteric infections in hospitalized patients with underlying strongyloidiasis. Am J Clin Pathol. 2007;128:622-7 pubmed
    Disseminated strongyloidiasis is often associated with enteric bacterial infections...
  19. Machado E, Carlos D, Lourenço E, Sorgi C, Silva E, Ramos S, et al. Counterregulation of Th2 immunity by interleukin 12 reduces host defenses against Strongyloides venezuelensis infection. Microbes Infect. 2009;11:571-8 pubmed publisher
    ..Together, our results showed that the absence of IL-12 upregulates the Th2 immune response, which is important for control of S. venezuelensis infection...
  20. Hsieh Y, Wen Y, Chen M. Minimal change nephrotic syndrome in association with strongyloidiasis. Clin Nephrol. 2006;66:459-63 pubmed
    ..Although parasitic infections have been known to be associated with immune complex-mediated glomerular lesions, strongyloidiasis-related glomerulopathy has not been well documented...
  21. Verweij J, Canales M, Polman K, Ziem J, Brienen E, Polderman A, et al. Molecular diagnosis of Strongyloides stercoralis in faecal samples using real-time PCR. Trans R Soc Trop Med Hyg. 2009;103:342-6 pubmed publisher
    ..stercoralis infections, with a two-fold increase in the detection rate as compared with the commonly used Baermann sedimentation method...
  22. Rivasi F, Pampiglione S, Boldorini R, Cardinale L. Histopathology of gastric and duodenal Strongyloides stercoralis locations in fifteen immunocompromised subjects. Arch Pathol Lab Med. 2006;130:1792-8 pubmed
    b>Strongyloidiasis is a worldwide parasitic infection affecting approximately 75 million people. In Italy, it was more prevalent in the past among rural populations of irrigated areas...
  23. Boulware D, Stauffer W, Hendel Paterson B, Rocha J, Seet R, Summer A, et al. Maltreatment of Strongyloides infection: case series and worldwide physicians-in-training survey. Am J Med. 2007;120:545.e1-8 pubmed
    b>Strongyloidiasis infects hundreds of millions of people worldwide and is an important cause of mortality from intestinal helminth infection in developed countries...
  24. Morrell M, Dallas J, Kollef M. A 50-year-old woman with abdominal pain and respiratory failure 3 months after kidney transplantation. Chest. 2008;134:442-446 pubmed publisher
  25. Hamilton K, Abt P, Rosenbach M, Bleicher M, Levine M, Mehta J, et al. Donor-derived Strongyloides stercoralis infections in renal transplant recipients. Transplantation. 2011;91:1019-24 pubmed publisher
    ..One patient was treated successfully with oral ivermectin. The other patient also had complete resolution of strongyloidiasis, but required a course of parenteral ivermectin because of malabsorption from severe gastrointestinal ..
  26. Showler A, Boggild A. Strongyloidiasis presenting as larva currens 38 years after presumed exposure. J Cutan Med Surg. 2012;16:433-5 pubmed
    We present a case of strongyloidiasis presenting as larva currens 38 years after potential exposure in a country with what is typically thought of as low epidemiologic risk...
  27. Qazilbash M, Ueno N, Hosing C, De Lima M, Cortes J, Massaro A, et al. Strongyloidiasis after unrelated nonmyeloablative allogeneic stem cell transplantation. Bone Marrow Transplant. 2006;38:393-4 pubmed
  28. Thompson F, Barker G, Hughes L, Viney M. Genes important in the parasitic life of the nematode Strongyloides ratti. Mol Biochem Parasitol. 2008;158:112-9 pubmed publisher
    ..ratti and, perhaps, other parasitic nematodes. These analyses have identified genes likely to play a key role in the parasitic life of S. ratti; these genes should be the priority for further investigation...
  29. Buonfrate D, Requena Méndez A, Angheben A, Munoz J, Gobbi F, Van Den Ende J, et al. Severe strongyloidiasis: a systematic review of case reports. BMC Infect Dis. 2013;13:78 pubmed publisher
    b>Strongyloidiasis is commonly a clinically unapparent, chronic infection, but immuno suppressed subjects can develop fatal disease...
  30. Yoshida H, Endo H, Tanaka S, Ishikawa A, Kondo H, Nakamura T. Recurrent paralytic ileus associated with strongyloidiasis in a patient with systemic lupus erythematosus. Mod Rheumatol. 2006;16:44-7 pubmed
    We present an interesting case of recurrent paralytic ileus due to strongyloidiasis in a woman who was being treated with corticosteroids and immunosuppressants for systemic lupus erythematosus (SLE)...
  31. Kishimoto K, Hokama A, Hirata T, Ihama Y, Nakamoto M, Kinjo N, et al. Endoscopic and histopathological study on the duodenum of Strongyloides stercoralis hyperinfection. World J Gastroenterol. 2008;14:1768-73 pubmed
    ..stercoralis hyperinfection who had had an esophagogastroduodenoscopy before undergoing treatment for strongyloidiasis. The clinical and endoscopic findings were analyzed retrospectively...
  32. Glinz D, N Guessan N, Utzinger J, N Goran E. High prevalence of Strongyloides stercoralis among school children in rural Côte d'Ivoire. J Parasitol. 2010;96:431-3 pubmed publisher
    ..an important parasite from a public health perspective, surveys should consider the use of appropriate diagnostic methods to further our understanding of the epidemiology of strongyloidiasis and to better target control interventions.
  33. Olsen A, van Lieshout L, Marti H, Polderman T, Polman K, Steinmann P, et al. Strongyloidiasis--the most neglected of the neglected tropical diseases?. Trans R Soc Trop Med Hyg. 2009;103:967-72 pubmed publisher
    ..stercoralis infections range from asymptomatic light infections to chronic symptomatic strongyloidiasis. Uncontrolled multiplication of the parasite (hyperinfection) and potentially life-threatening dissemination ..
  34. Abrescia F, Falda A, Caramaschi G, Scalzini A, Gobbi F, Angheben A, et al. Reemergence of strongyloidiasis, northern Italy. Emerg Infect Dis. 2009;15:1531-3 pubmed publisher
  35. Marques C, da Penha Zago Gomes M, Goncalves C, Pereira F. Alcoholism and Strongyloides stercoralis: daily ethanol ingestion has a positive correlation with the frequency of Strongyloides larvae in the stools. PLoS Negl Trop Dis. 2010;4:e717 pubmed publisher
    ..These results confirm and reinforce the hypothesis that chronic alcoholism is associated with Strongyloides infection, which is in direct relationship with the severity of alcoholism, independently of the presence of liver cirrhosis. ..
  36. Sudré A, Siqueira R, Barreto M, Peralta R, Macedo H, Peralta J. Identification of a 26-kDa protein fraction as an important antigen for application in the immunodiagnosis of strongyloidiasis. Parasitol Res. 2007;101:1117-23 pubmed
    b>Strongyloidiasis caused by the intestinal nematode Strongyloides stercoralis typically occurs in the asymptomatic form. The definitive diagnosis is usually done by detection of larvae on fecal samples...
  37. Greiner K, Bettencourt J, Semolic C. Strongyloidiasis: a review and update by case example. Clin Lab Sci. 2008;21:82-8 pubmed
    ..Review the pathogenesis, diagnosis and treatment of strongyloidiasis; alert laboratory professionals to the importance of early detection of Strongyloides stercoralis in ..
  38. Padigel U, Hess J, Lee J, Lok J, Nolan T, Schad G, et al. Eosinophils act as antigen-presenting cells to induce immunity to Strongyloides stercoralis in mice. J Infect Dis. 2007;196:1844-51 pubmed publisher
    ..These experiments demonstrate that eosinophils function as antigen-presenting cells for the induction of the primary and the expansion of the secondary Th2 immune responses to S. stercoralis in mice. ..
  39. Marcilla A, Sotillo J, Perez Garcia A, Igual Adell R, Valero M, Sánchez Pino M, et al. Proteomic analysis of Strongyloides stercoralis L3 larvae. Parasitology. 2010;137:1577-83 pubmed publisher
    b>Strongyloidiasis can be perpetuated by autoinfection with the filariform larvae L3, causing asymptomatic chronic infections and creating a population of carriers, affecting not only developing countries...
  40. Blankenhaus B, Klemm U, Eschbach M, Sparwasser T, Huehn J, Kuhl A, et al. Strongyloides ratti infection induces expansion of Foxp3+ regulatory T cells that interfere with immune response and parasite clearance in BALB/c mice. J Immunol. 2011;186:4295-305 pubmed publisher
    ..Taken together, we provide evidence that Treg expansion during S. ratti infection suppresses the protective immune response to this pathogenic nematode and, thus, represents a mechanism of immune evasion...
  41. Posey D, Blackburn B, Weinberg M, Flagg E, Ortega L, Wilson M, et al. High prevalence and presumptive treatment of schistosomiasis and strongyloidiasis among African refugees. Clin Infect Dis. 2007;45:1310-5 pubmed
    Schistosomiasis and strongyloidiasis cause substantial morbidity and mortality among hundreds of millions of infected persons worldwide...
  42. Ramanathan R, Burbelo P, Groot S, Iadarola M, Neva F, Nutman T. A luciferase immunoprecipitation systems assay enhances the sensitivity and specificity of diagnosis of Strongyloides stercoralis infection. J Infect Dis. 2008;198:444-51 pubmed publisher
    ..We investigated whether luciferase immunoprecipitation systems (LIPS) can be the basis for a more rapid, specific, and standardized assay for the diagnosis of Strongyloides stercoralis infection...
  43. Taniuchi M, Verweij J, Noor Z, Sobuz S, Lieshout L, Petri W, et al. High throughput multiplex PCR and probe-based detection with Luminex beads for seven intestinal parasites. Am J Trop Med Hyg. 2011;84:332-7 pubmed publisher
    ..In conclusion, this multiplex PCR-bead protocol provides a sensitive diagnostic screen for a large panel of intestinal parasites...
  44. Massoud A, El Shazly A, Awad S, Morsy A, Sadek G, Morsy T. New trends in diagnosis and treatment of chronic intestinal strongyloidiasis stercoralis in Egyptian patients. J Egypt Soc Parasitol. 2006;36:827-44 pubmed
    b>Strongyloidiasis, caused by Strongyloides stercoralis, is diagnosis considered as a challenge to clinician and laboratory technician...
  45. Vithayasai N, Jennuvat S. Gastrointestinal manifestations in severe strongyloidiasis: report of 3 cases and literature review. Southeast Asian J Trop Med Public Health. 2010;41:22-7 pubmed
    We report here three cases of severe strongyloidiasis in normal and immunocompromised hosts. The first was a patient with a normal immune system who presented with acute severe abdominal pain...
  46. Mattioni S, Valin N, Cracco C, Thellier M, Danis M, Caumes E. Fatal relapse of disseminated strongyloidiasis in an HIV-positive patient, despite ivermectin treatment. Ann Trop Med Parasitol. 2008;102:693-8 pubmed publisher
    There are no established guidelines for the treatment of disseminated strongyloidiasis in immunosuppressed patients, and many different treatment regimens have been used...
  47. Feely N, Waghorn D, Dexter T, Gallen I, Chiodini P. Strongyloides stercoralis hyperinfection: difficulties in diagnosis and treatment. Anaesthesia. 2010;65:298-301 pubmed publisher
    ..Once the diagnosis of strongyloidiasis was made, the patient was successfully treated with subcutaneous antihelminthic drugs...
  48. Foreman E, Abraham P, Garland J. Not your typical strongyloides infection: a literature review and case study. South Med J. 2006;99:847-52 pubmed
    Strongyloides hyperinfection syndrome is one of several clinical manifestations of strongyloidiasis and has a mortality rate exceeding 85%...
  49. Drug V, Haliga R, Akbar Q, Mihai C, Cijevschi Prelipcean C, Stanciu C. Ascites with Strongyloides stercoralis in a patient with acute alcoholic pancreatitis and liver cirrhosis. J Gastrointestin Liver Dis. 2009;18:367-9 pubmed
    ..The patient had no evident immunosupression (HIV negative and absence of immunosupressive therapy). This is the first reported case where acute pancreatitis could have precipitated infection of ascitic fluid with S. stercoralis. ..
  50. Malnick S, Somin M, Beilinson N, Basevitch A, Bregman G, Zimhony O. Strongyloides hyperinfection in Ethiopian immigrants in Israel. Isr Med Assoc J. 2009;11:660-3 pubmed
    ..Testing for Strongyloides infestation in this susceptible population by enzyme-linked immunosorbent assay serology, stool testing or duodenal aspiration may prevent the fatal complications of hyperinfection. ..
  51. Boscolo M, Gobbo M, Mantovani W, Degani M, Anselmi M, Monteiro G, et al. Evaluation of an indirect immunofluorescence assay for strongyloidiasis as a tool for diagnosis and follow-up. Clin Vaccine Immunol. 2007;14:129-33 pubmed
    ..To assess diagnostic sensitivity, sera from 156 patients with known strongyloidiasis were collected...
  52. Eschbach M, Klemm U, Kolbaum J, Blankenhaus B, Brattig N, Breloer M. Strongyloides ratti infection induces transient nematode-specific Th2 response and reciprocal suppression of IFN-gamma production in mice. Parasite Immunol. 2010;32:370-83 pubmed publisher
    ..Finally, comparing artificial infections induced by subcutaneous injection of larvae to natural infections, we observed similar antigen-specific T cell responses although the natural infection led to a significantly lower worm burden...
  53. Angheben A, Mistretta M, Gobbo M, Bonafini S, Iacovazzi T, Sepe A, et al. Acute strongyloidiasis in Italian tourists returning from Southeast Asia. J Travel Med. 2011;18:138-40 pubmed publisher
    b>Strongyloidiasis is a soil-transmitted helmithiasis with worldwide distribution. Contrary to chronic form, hyperinfestation and life-threatening dissemination, first (invasive) stages of the disease are not well characterized...
  54. Requena Méndez A, Chiodini P, Bisoffi Z, Buonfrate D, Gotuzzo E, Munoz J. The laboratory diagnosis and follow up of strongyloidiasis: a systematic review. PLoS Negl Trop Dis. 2013;7:e2002 pubmed publisher
    b>Strongyloidiasis is frequently under diagnosed since many infections remain asymptomatic and conventional diagnostic tests based on parasitological examination are not sufficiently sensitive...
  55. Fardet L, Genereau T, Cabane J, Kettaneh A. Severe strongyloidiasis in corticosteroid-treated patients. Clin Microbiol Infect. 2006;12:945-7 pubmed
    Severe strongyloidiasis, caused by Strongyloides stercoralis, is a preventable life-threatening disease that can occur in any corticosteroid-treated patient who has travelled to a country with infested soil, even if the contact occurred ..
  56. Bangs M, Sirait S, Purnomo -, Maguire J. Strongyloidiasis with gastric mucosal invasion presenting with acute interstitial nephritis. Southeast Asian J Trop Med Public Health. 2006;37:641-7 pubmed
    ..stercoralis filariform larvae and free-living adult worms, corroborating the diagnosis. The infection was associated with acute interstitial nephritis. The patient showed rapid and dramatic improvement after treatment with mebendazole...
  57. Boscolo M, Bisoffi Z. Dissemination: the fatal risk for a missed diagnosis of Strongyloides stercoralis infection. J Infect. 2007;55:284-5 pubmed
  58. Ali H, Walkenstein M. Bilateral nodular pulmonary infiltrates in an immunocompromised host. Thorax. 2008;63:746, 753 pubmed publisher
  59. Pattison D, Speare R. Strongyloidiasis in personnel of the Regional Assistance Mission to Solomon Islands (RAMSI). Med J Aust. 2008;189:203-6 pubmed
    To investigate the first reported cases of strongyloidiasis in the Solomon Islands, and to establish whether this disease poses a risk to personnel of the Regional Assistance Mission to Solomon Islands (RAMSI).
  60. Agrawal V, Agarwal T, Ghoshal U. Intestinal strongyloidiasis: a diagnosis frequently missed in the tropics. Trans R Soc Trop Med Hyg. 2009;103:242-6 pubmed publisher
    ..The initial stool examination and peripheral blood eosinophil count were normal in all patients. Strongyloidiasis was not suspected clinically in any patient and the diagnosis was achieved on endoscopic biopsy...
  61. Steinmann P, Zhou X, Du Z, Jiang J, Xiao S, Wu Z, et al. Tribendimidine and albendazole for treating soil-transmitted helminths, Strongyloides stercoralis and Taenia spp.: open-label randomized trial. PLoS Negl Trop Dis. 2008;2:e322 pubmed publisher
  62. Biggs B, Caruana S, Mihrshahi S, Jolley D, Leydon J, Chea L, et al. Management of chronic strongyloidiasis in immigrants and refugees: is serologic testing useful?. Am J Trop Med Hyg. 2009;80:788-91 pubmed
    We assessed the usefulness of serologic testing in monitoring strongyloidiasis in immigrants after treatment with two doses of ivermectin...
  63. Bon B, Houze S, Talabani H, Magne D, Belkadi G, Develoux M, et al. Evaluation of a rapid enzyme-linked immunosorbent assay for diagnosis of strongyloidiasis. J Clin Microbiol. 2010;48:1716-9 pubmed publisher
    Diagnosis of strongyloidiasis using stool examination remains unsatisfactory due to the lack of sensitivity and fastidious techniques...
  64. Bonne Annee S, Hess J, Abraham D. Innate and adaptive immunity to the nematode Strongyloides stercoralis in a mouse model. Immunol Res. 2011;51:205-14 pubmed publisher
    ..These studies demonstrate that there are redundancies in the mechanisms used by the immune response to kill the parasite and that a vaccine with a single antigen may be suitable as a prophylactic vaccine to prevent human strongyloidiasis.
  65. Wang C, Xu J, Zhou X, Li J, Yan G, James A, et al. Strongyloidiasis: an emerging infectious disease in China. Am J Trop Med Hyg. 2013;88:420-5 pubmed publisher
    Since the first case of strongyloidiasis reported in China in 1973, there have been 330 confirmed cases as of 2011...
  66. Mir A, Benahmed D, Igual R, Borras R, O Connor J, Moreno M, et al. Eosinophil-selective mediators in human strongyloidiasis. Parasite Immunol. 2006;28:397-400 pubmed
    ..namely eotaxin and interleukin-5 (IL-5), using an enzyme-linked immunosorbent assay in patients with strongyloidiasis. Serum expression of eotaxin and IL-5 were significantly increased in patients compared with the control ..
  67. Hirata T, Kishimoto K, Kinjo N, Hokama A, Kinjo F, Fujita J. Association between Strongyloides stercoralis infection and biliary tract cancer. Parasitol Res. 2007;101:1345-8 pubmed
    ..stercoralis infection in patients with biliary tract cancer appears significantly higher than that in control patients. Thus, we propose that S. stercoralis infection is a risk factor for biliary tract cancer...
  68. Rajapurkar M, Hegde U, Rokhade M, Gang S, Gohel K. Respiratory hyperinfection with Strongyloides stercoralis in a patient with renal failure. Nat Clin Pract Nephrol. 2007;3:573-7 pubmed
    ..The patient's fever did not respond to empirical antibiotics or antitubercular therapy. Bronchoscopic alveolar lavage and stool examination revealed larval forms of Strongyloides stercoralis...
  69. Das P, Raghu P, Amit Kumar Dinda -, Garg P. Strongyloides hyperinfection in rheumatoid arthritis. Int J Surg Pathol. 2007;15:391-2 pubmed
  70. Hasegawa H, Hayashida S, Ikeda Y, Sato H. Hyper-variable regions in 18S rDNA of Strongyloides spp. as markers for species-specific diagnosis. Parasitol Res. 2009;104:869-74 pubmed publisher
  71. Pinatelle P, de Monbrison F, Bedock B. [Disseminated strongyloidiasis with parasitemia in a patient under corticosteroid-treatment]. Med Mal Infect. 2009;39:267-9 pubmed publisher
    We report a case of disseminated strongyloidiasis with parasitemia in a 53-year-old man under corticosteroid therapy. It occurred more than 16years after contamination and led to severe sepsis and acute respiratory failure with P...
  72. Bava A, Troncoso A. Strongyloides stercoralis hyperinfection in a patient with AIDS. J Int Assoc Physicians AIDS Care (Chic). 2009;8:235-8 pubmed publisher
    ..We report a case of S stercoralis hyperinfection in an HIV-infected patient, which resulted in death...
  73. Dawson Hahn E, Greenberg S, Domachowske J, Olson B. Eosinophilia and the seroprevalence of schistosomiasis and strongyloidiasis in newly arrived pediatric refugees: an examination of Centers for Disease Control and Prevention screening guidelines. J Pediatr. 2010;156:1016-1018.e1 pubmed publisher
    ..recommend examination of the absolute eosinophil count (AEC) to screen for asymptomatic schistosomiasis and strongyloidiasis. We examined the predictive validity of an AEC >400 cells/microL to identify refugees with serologic ..
  74. Hasegawa H, Sato H, Fujita S, Nguema P, Nobusue K, Miyagi K, et al. Molecular identification of the causative agent of human strongyloidiasis acquired in Tanzania: dispersal and diversity of Strongyloides spp. and their hosts. Parasitol Int. 2010;59:407-13 pubmed publisher
    In order to identify the causative agent of imported strongyloidiasis found in a Japanese mammalogist, who participated in a field survey in Tanzania, the hyper-variable region IV (HVR-IV) of 18S ribosomal DNA and partial mitochondrial ..
  75. Khieu V, Schär F, Marti H, Sayasone S, Duong S, Muth S, et al. Diagnosis, treatment and risk factors of Strongyloides stercoralis in schoolchildren in Cambodia. PLoS Negl Trop Dis. 2013;7:e2035 pubmed publisher
    ..stercoralis infections, using a multiple stool examination approach; and assessed efficacy of ivermectin treatment...
  76. Gillet N, Cook L, Laydon D, Hlela C, Verdonck K, Alvarez C, et al. Strongyloidiasis and infective dermatitis alter human T lymphotropic virus-1 clonality in vivo. PLoS Pathog. 2013;9:e1003263 pubmed publisher
    ..HTLV-1 causes a neuroinflammatory disease and adult T-cell leukemia/lymphoma. Strongyloidiasis, a gastrointestinal infection by the helminth Strongyloides stercoralis, and Infective Dermatitis associated ..
  77. Werneck Silva A, Alvares E, Gama P, Damiao A, Osaki L, Ogias D, et al. Intestinal damage in strongyloidiasis: the imbalance between cell death and proliferation. Dig Dis Sci. 2006;51:1063-9 pubmed
    b>Strongyloidiasis is an endemic tropical parasitosis caused by Strongyloides stercoralis that also affects immigrants in nontropical countries. The nematode colonizes the duodenum and upper jejunum, inducing mucosal alterations...
  78. Csermely L, Jaafar H, Kristensen J, Castella A, Gorka W, Chebli A, et al. Strongyloides hyper-infection causing life-threatening gastrointestinal bleeding. World J Gastroenterol. 2006;12:6401-4 pubmed
    ..Indeed, steroid therapy of vasculitis with other means of supportive care resulted in cessation of the bleeding and recovery of the patient...
  79. Vaiyavatjamai P, Boitano J, Techasintana P, Tungtrongchitr A. Immunocompromised group differences in the presentation of intestinal strongyloidiasis. Jpn J Infect Dis. 2008;61:5-8 pubmed
    ..For HIV patients with strongyloidiasis, the most common symptoms were chronic diarrhea, fever, persistent coughing and loss of weight, but only the ..
  80. Keiser J, Thiemann K, Endriss Y, Utzinger J. Strongyloides ratti: in vitro and in vivo activity of tribendimidine. PLoS Negl Trop Dis. 2008;2:e136 pubmed publisher
    b>Strongyloidiasis is a truly neglected tropical disease, but its public health significance is far from being negligible. At present, only a few drugs are available for the treatment and control of strongyloidiasis.
  81. Vadlamudi R, Van Dort M, Barklow T, Byrd R, Moorman J. Strongyloides hyperinfection syndrome complicating (ectopic) Cushing syndrome. South Med J. 2008;101:750-2 pubmed publisher
    b>Strongyloidiasis can present with a wide variety of symptoms and can lead to a potentially fatal hyperinfection...
  82. Montes M, Sanchez C, Verdonck K, Lake J, Gonzalez E, Lopez G, et al. Regulatory T cell expansion in HTLV-1 and strongyloidiasis co-infection is associated with reduced IL-5 responses to Strongyloides stercoralis antigen. PLoS Negl Trop Dis. 2009;3:e456 pubmed publisher
    Human strongyloidiasis varies from a chronic but limited infection in normal hosts to hyperinfection in patients treated with corticosteroids or with HTLV-1 co-infection. Regulatory T cells dampen immune responses to infections...
  83. El Badry A. ELISA-based coproantigen in human strongyloidiaisis: a diagnostic method correlating with worm burden. J Egypt Soc Parasitol. 2009;39:757-68 pubmed
    In order to overcome the false negative diagnosis of strongyloidiasis in the absence of rhabditiform larvae in stools, an ELISA-based Strongyloides stercoralis-specific coproantigen detection assay in stools of infected patients was ..
  84. Incani R, Hernandez M, Cortez J, Gonzalez M, Salazar Y. Staphylococcus warneri meningitis in a patient with Strongyloides stercoralis hyperinfection and lymphoma: first report of a case. Rev Inst Med Trop Sao Paulo. 2010;52:169-70 pubmed
    ..lymphoma after treatment with chemotherapy-immunotherapy and then immunotherapy alone, and diagnosis of strongyloidiasis. Meningitis was diagnosed by cerebrospinal fluid culture and tested with an automated plate system...
  85. Murali A, Rajendiran G, Ranganathan K, Shanthakumari S. Disseminated infection with Strongyloides stercoralis in a diabetic patient. Indian J Med Microbiol. 2010;28:407-8 pubmed publisher
    ..A follow-up echo done at discharge showed no pericardial effusion and the patient was completely asymptomatic. To our knowledge, this is the first reported case of Strongyloides pericardial effusion in a diabetic patient...
  86. Gonzaga H, Ribeiro V, Feliciano N, Manhani M, Silva D, Ueta M, et al. IgG avidity in differential serodiagnosis of human strongyloidiasis active infection. Immunol Lett. 2011;139:87-92 pubmed publisher
    ..avidity assays have been developed for several parasitic diseases although there are no researches focused in strongyloidiasis diagnosis...
  87. Jeyamani R, Joseph A, Chacko A. Severe and treatment resistant strongyloidiasis--indicator of HTLV-I infection. Trop Gastroenterol. 2007;28:176-7 pubmed
    The association between severe and persistent strongyloidiasis with human T cell lymphotropic virus type I (HTLV-1) infection is well documented in reports from HTLV-1 endemic regions like Japan and Jamaica...
  88. Liu H, Hsu J, Chang K. Strongyloides stercoralis hyperinfection presenting with symptoms mimicking acute exacerbation of chronic obstructive pulmonary disease. J Chin Med Assoc. 2009;72:442-5 pubmed publisher
    ..We suggest that a screening test be done for patients who live in endemic areas and those who are going to receive steroids for chronic disease...
  89. Galimberti R, Pontón A, Zaputovich F, Velasquez L, Galimberti G, Torre A, et al. Disseminated strongyloidiasis in immunocompromised patients--report of three cases. Int J Dermatol. 2009;48:975-8 pubmed publisher
    Strongyloides stercoralis is an intestinal nematode of humans. The characteristic cutaneous manifestation of strongyloidiasis is larva currens...
  90. Iriemenam N, Sanyaolu A, Oyibo W, Fagbenro Beyioku A. Strongyloides stercoralis and the immune response. Parasitol Int. 2010;59:9-14 pubmed publisher
    ..The solution to reducing the prevalence of strongyloidiasis remains on the effectiveness of pre-emptive measures in endemic communities, increased awareness, prompt ..
  91. Repetto S, Durán P, Lasala M, Gonzalez Cappa S. High rate of strongyloidosis infection, out of endemic area, in patients with eosinophilia and without risk of exogenous reinfections. Am J Trop Med Hyg. 2010;82:1088-93 pubmed publisher
    ..stercoralis infection to prevent disseminated infections secondary to corticoid therapy...
  92. Kramme S, Nissen N, Soblik H, Erttmann K, Tannich E, Fleischer B, et al. Novel real-time PCR for the universal detection of Strongyloides species. J Med Microbiol. 2011;60:454-8 pubmed publisher
    b>Strongyloidiasis is a neglected disease that is prevalent mainly in tropical and subtropical regions. It is caused by intestinal nematodes of the genus Strongyloides...