vestibular neuronitis

Summary

Summary: Idiopathic inflammation of the VESTIBULAR NERVE, characterized clinically by the acute or subacute onset of VERTIGO; NAUSEA; and imbalance. The COCHLEAR NERVE is typically spared and HEARING LOSS and TINNITUS do not usually occur. Symptoms usually resolve over a period of days to weeks. (Adams et al., Principles of Neurology, 6th ed, p304)

Top Publications

  1. Gacek R, Gacek M. Vestibular neuronitis: a viral neuropathy. Adv Otorhinolaryngol. 2002;60:54-66 pubmed
  2. Godemann F, Linden M, Neu P, Heipp E, Dörr P. A prospective study on the course of anxiety after vestibular neuronitis. J Psychosom Res. 2004;56:351-4 pubmed
    ..Critical life events trigger intense emotions. Anxiety is one of the most frequent of these emotions. It is unclear which factors determine the intensity and course of anxiety after a critical life event...
  3. Lee H, Sohn S, Cho Y, Lee S, Ahn B, Park B, et al. Cerebellar infarction presenting isolated vertigo: frequency and vascular topographical patterns. Neurology. 2006;67:1178-83 pubmed
    ..To determine the frequency of cerebellar infarction mimicking vestibular neuritis (VN), the pattern of clinical presentation, and the territory of the cerebellar infarction when it simulates VN...
  4. Goebel J, O Mara W, Gianoli G. Anatomic considerations in vestibular neuritis. Otol Neurotol. 2001;22:512-8 pubmed
    ..The purpose of the study was to investigate anatomic differences between the superior vestibular nerve and singular nerve canals...
  5. Schmid Priscoveanu A, Böhmer A, Obzina H, Straumann D. Caloric and search-coil head-impulse testing in patients after vestibular neuritis. J Assoc Res Otolaryngol. 2001;2:72-8 pubmed
    ..Chronic patients, however, were reliably identified only by search-coil head-impulse testing, which suggests that the low-frequency function of the labyrinths often becomes symmetrical, leading to a normal canal paresis factor...
  6. Cutfield N, Cousins S, Seemungal B, Gresty M, Bronstein A. Vestibular perceptual thresholds to angular rotation in acute unilateral vestibular paresis and with galvanic stimulation. Ann N Y Acad Sci. 2011;1233:256-62 pubmed publisher
  7. Dieterich M, Brandt T. Functional brain imaging of peripheral and central vestibular disorders. Brain. 2008;131:2538-52 pubmed publisher
  8. Strupp M, Brandt T. Vestibular neuritis. Semin Neurol. 2009;29:509-19 pubmed publisher
  9. Karlberg M, Magnusson M. Treatment of acute vestibular neuronitis with glucocorticoids. Otol Neurotol. 2011;32:1140-3 pubmed publisher
    To report the effects of glucocorticoid treatment of acute vestibular neuronitis on recovery of vestibular function and length of hospital stay.

More Information

Publications62

  1. Shupak A, Nachum Z, Stern Y, Tal D, Gil A, Gordon C. Vestibular neuronitis in pilots: follow-up results and implications for flight safety. Laryngoscope. 2003;113:316-21 pubmed
    OBJECTIVES To report our experience over the past 12 years with the evaluation and follow-up of pilots with vestibular neuronitis and to discuss points relevant to flight safety and the resumption of flying duties...
  2. Alessandrini M, Napolitano B, Bruno E, Belcastro L, Ottaviani F, Schillaci O. Cerebral plasticity in acute vestibular deficit. Eur Arch Otorhinolaryngol. 2009;266:1547-51 pubmed publisher
  3. Bense S, Bartenstein P, Lochmann M, Schlindwein P, Brandt T, Dieterich M. Metabolic changes in vestibular and visual cortices in acute vestibular neuritis. Ann Neurol. 2004;56:624-30 pubmed
    ..Contrary to experimental vestibular stimulation, the activation of the vestibular cortex was not bilateral but was unilateral and contralateral to the right-sided labyrinthine failure...
  4. Milionis H, Mittari V, Exarchakos G, Kalaitzidis R, Skevas A, Elisaf M. Lipoprotein (a) and acute-phase response in patients with vestibular neuronitis. Eur J Clin Invest. 2003;33:1045-50 pubmed
    b>Vestibular neuronitis (VN) is a relatively common condition characterized by the acute onset of vertigo, nausea and vomiting, in the absence of auditory or central nervous system involvement...
  5. Ochi K, Ohashi T, Watanabe S. Vestibular-evoked myogenic potential in patients with unilateral vestibular neuritis: abnormal VEMP and its recovery. J Laryngol Otol. 2003;117:104-8 pubmed
    ..Disorders of the inferior vestibular nerve function and their recovery was confirmed by our current results. The time course of recoveries of the superior and inferior vestibular nerve systems were similar in the two patients...
  6. Matsuzaki M, Murofushi T. Vestibular evoked myogenic potentials in patients with idiopathic bilateral vestibulopathy. Report of three cases. ORL J Otorhinolaryngol Relat Spec. 2001;63:349-52 pubmed
    ..As previously reported in the cases of vestibular neuritis, VEMP could be useful for classifying IBV according to the function of the inferior vestibular nerve...
  7. Helmchen C, Klinkenstein J, Machner B, Rambold H, Mohr C, Sander T. Structural changes in the human brain following vestibular neuritis indicate central vestibular compensation. Ann N Y Acad Sci. 2009;1164:104-15 pubmed publisher
    ..As increase of GMV was related to an improvement of vestibular function, structural alterations may be related to central vestibular compensation...
  8. zu Eulenburg P, Stoeter P, Dieterich M. Voxel-based morphometry depicts central compensation after vestibular neuritis. Ann Neurol. 2010;68:241-9 pubmed publisher
    ..Patients who have had vestibular neuritis (VN) show a remarkable clinical improvement especially in gait and posture >6 months after disease onset...
  9. Aw S, Fetter M, Cremer P, Karlberg M, Halmagyi G. Individual semicircular canal function in superior and inferior vestibular neuritis. Neurology. 2001;57:768-74 pubmed
    ..To examine the concept of selective superior and inferior vestibular nerve involvement in vestibular neuritis by studying the distribution of semicircular canal (SCC) involvement in such patients...
  10. Zingler V, Weintz E, Jahn K, Mike A, Huppert D, Rettinger N, et al. Follow-up of vestibular function in bilateral vestibulopathy. J Neurol Neurosurg Psychiatry. 2008;79:284-8 pubmed
    ..The main goal of this study was to determine the frequency and degree of recovery or worsening of vestibular function over time...
  11. Huppert D, Strupp M, Theil D, Glaser M, Brandt T. Low recurrence rate of vestibular neuritis: a long-term follow-up. Neurology. 2006;67:1870-1 pubmed
    ..VN affected the contralateral ear in both and caused less severe distressing vertigo and postural imbalance. Unlike Bell's palsy and sudden hearing loss, a relapse in the same ear did not occur...
  12. Guan Q, Zhang L, Hong W, Yang Y, Chen Z, Zhang D, et al. [Video head impulse test for evaluation of vestibular function in patients with vestibular neuritis and benign paroxysmal positional vertigo]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2017;46:52-58 pubmed
    ..b>Conclusion: Video head impulse test can quantitatively evaluate the vestibular dysfunction of VN and can help early diagnosis of VN, which may be widely used in clinic. ..
  13. Alessandrini M, D Erme G, Bruno E, Napolitano B, Magrini A. Vestibular compensation: analysis of postural re-arrangement as a control index for unilateral vestibular deficit. Neuroreport. 2003;14:1075-9 pubmed
    ..Our results seem to provide an early index of a proper occurring compensation so that we can adjust therapeutic protocols according to each patient's functional modifications...
  14. Allum J, Honegger F. Relation between head impulse tests, rotating chair tests, and stance and gait posturography after an acute unilateral peripheral vestibular deficit. Otol Neurotol. 2013;34:980-9 pubmed publisher
  15. Rapoport A, Kupchik M, Gilad R, Lampl Y, Sadeh M. Laboral outcome after acute unilateral vestibulopathy. Neurol Neurochir Pol. 2001;35 Suppl 3:45-9 pubmed
    ..Older individuals had significantly attributed a change in work to disease other than APV. Change attributed to APV occurred significantly more frequently in women than in men. The therapeutic approach seems beneficial...
  16. Pollak L, Book M, Smetana Z, Alkin M, Soupayev Z, Mendelson E. Herpes simplex virus type 1 in saliva of patients with vestibular neuronitis: a preliminary study. Neurologist. 2011;17:330-2 pubmed publisher
    b>Vestibular neuronitis (VN) is an inflammatory disease of the vestibular nerve, presumably caused by reactivation of the herpes simplex virus type l (HSV-1)...
  17. Venail F, Biboulet R, Mondain M, Uziel A. A protective effect of 5-HT3 antagonist against vestibular deficit? Metoclopramide versus ondansetron at the early stage of vestibular neuritis: a pilot study. Eur Ann Otorhinolaryngol Head Neck Dis. 2012;129:65-8 pubmed publisher
    ..Ondansetron is an antiemetic 5-HT3 receptor antagonist with proven efficacy in central balance disorder. A pilot study investigated impact on acute unilateral vestibular neuritis...
  18. Fundakowski C, Anderson J, Angeli S. Cross-sectional vestibular nerve analysis in vestibular neuritis. Ann Otol Rhinol Laryngol. 2012;121:466-70 pubmed
  19. Lorin P, Manceau C, Foubert F. Effect of vestibular neuritis on postural control using wavelets and fractal analysis. Rev Laryngol Otol Rhinol (Bord). 2010;131:235-41 pubmed
  20. Jáuregui Renaud K, Hermosillo A, Gómez A, Marquez M, Cardenas M, Bronstein A. Vestibular function interferes in cardiovascular reflexes [corrected]. Arch Med Res. 2003;34:200-4 pubmed
    ..However, there are no studies of cardiovascular reflexes during vertigo due to human acute vestibular lesions...
  21. Strupp M, Arbusow V, Brandt T. Exercise and drug therapy alter recovery from labyrinth lesion in humans. Ann N Y Acad Sci. 2001;942:79-94 pubmed
    ..3) Preliminary results of an interim analysis from an ongoing randomized, prospective study showed that methylprednisolone (plus an antiviral agent?) may be useful for improving peripheral vestibular function in vestibular neuritis...
  22. Neuhauser H, Lempert T. Vertigo: epidemiologic aspects. Semin Neurol. 2009;29:473-81 pubmed publisher
  23. Califano L, Mazzone S, Salafia F. Utility of the hyperventilation test in the evaluation of the dizzy patient. Curr Opin Otolaryngol Head Neck Surg. 2013;21:487-91 pubmed publisher
  24. Hansen S, Ninn Pedersen M, Caye Thomasen P. [An oto-neurological approach to the acutely dizzy patient]. Ugeskr Laeger. 2011;173:2497-503 pubmed
    Benign paroxysmal positional vertigo, vestibular neuronitis and Menière's disease cause most cases of acute vertigo. However, doctors must consider central neurological reasons to vertigo...
  25. Roehm P, Camarena V, Nayak S, Gardner J, Wilson A, Mohr I, et al. Cultured vestibular ganglion neurons demonstrate latent HSV1 reactivation. Laryngoscope. 2011;121:2268-75 pubmed publisher
    ..We developed an in vitro system to study HSV1 infection of vestibular ganglion neurons (VGNs) using a cell culture model system...
  26. Baloh R, Halmagyi G, Zee D. The history and future of neuro-otology. Continuum (Minneap Minn). 2012;18:1001-15 pubmed publisher
    ..Since that time, scientific discovery has advanced our knowledge of the physiology and the pathophysiology of the vestibular system. This article describes where we have been, where we are now, and where we need to go from here...
  27. Morita S, Suzuki M, Iizuka K. False-negative diffusion-weighted MRI in acute cerebellar stroke. Auris Nasus Larynx. 2011;38:577-82 pubmed publisher
    ..To heighten physician awareness of false-negative diffusion-weighted (DW) magnetic-resonance imaging findings in patients with acute cerebellar infarction and the importance of periodically observing nystagmus after symptom onset...
  28. Ochi K, Ohashi T, Nishino H. Variance of vestibular-evoked myogenic potentials. Laryngoscope. 2001;111:522-7 pubmed
    ..In addition, clinical application of VEMP was examined in patients with acoustic tumors (ATs) and vestibular neurolabyrinthitis (VNL)...
  29. Best C, Eckhardt Henn A, Tschan R, Dieterich M. Psychiatric morbidity and comorbidity in different vestibular vertigo syndromes. Results of a prospective longitudinal study over one year. J Neurol. 2009;256:58-65 pubmed publisher
    ..The aim of this study was to evaluate the impact of vestibular function and vestibular deficits as well as preexisting psychiatric pathologies on the course of vestibular vertigo syndromes over 1 year...
  30. Bergenius J, Perols O. Vestibular neuritis: a follow-up study. Acta Otolaryngol. 1999;119:895-9 pubmed
    ..It is speculated whether the group of patients with residual symptoms had a different pathophysiological localization of their disease within the vestibular system than the group of patients with no symptoms at follow-up...
  31. Boniver R. [Recurrent paroxystic vertigo]. Rev Med Liege. 2004;59:326-30 pubmed
    ..The author describes the pathology, the symptoms and the treatment of these vertigo...
  32. Schneider E, Glasauer S, Dieterich M, Kalla R, Brandt T. Diagnosis of vestibular imbalance in the blink of an eye. Neurology. 2004;63:1209-16 pubmed
    ..On the basis of this observation, they hypothesized that blinks in patients with a vestibular tone imbalance would also trigger torsional quick phases...
  33. Heidenreich K, Carender W, Heidenreich M, Telian S. Strategies to distinguish benign paroxysmal positional vertigo from rotational vertebrobasilar ischemia. Ann Vasc Surg. 2010;24:553.e1-5 pubmed publisher
    ..Treatment of her BPPV led to complete resolution of her symptoms. A succinct overview of this common otologic disorder is provided, and strategies to help distinguish it from RVBI are discussed...
  34. Mandalà M, Santoro G, Awrey J, Nuti D. Vestibular neuritis: recurrence and incidence of secondary benign paroxysmal positional vertigo. Acta Otolaryngol. 2010;130:565-7 pubmed publisher
    ..To our knowledge, this study represents the only long-term longitudinal study on recurrence of VN and incidence of secondary BPPV in VN...
  35. Sazgar A, Yazdani N, Rezazadeh N, Yazdi A. Vestibular evoked myogenic potential (VEMP) in patients with auditory neuropathy: Auditory neuropathy or audiovestibular neuropathy?. Acta Otolaryngol. 2010;130:1130-4 pubmed publisher
    ..Our results suggest that isolated auditory or vestibular involvement is unlikely and in fact audiovestibular neuropathy can better explain auditory neuropathy...
  36. Volz Sidiropoulou E, Takahama J, Gauggel S, Westhofen M. [The 'dizziness handicap inventory': initial psychometric evaluation of the German version]. Laryngorhinootologie. 2010;89:418-23 pubmed publisher
    ..Standardized instruments such as the "Dizziness Handicap Inventory" (DHI) help clinicians assess this impact systematically. The purpose of this study was to analyse the psychometric quality of a German version of the DHI...
  37. Corvera J, Corvera Behar G, Lapilover V, Ysunza A. Objective evaluation of the effect of flunarizine on vestibular neuritis. Otol Neurotol. 2002;23:933-7 pubmed
    ..To determine whether vestibular autorotation tests (VAT) would show significant differences in vestibular oculomotor reflex (VOR) parameters in vertiginous patients before and after treatment with flunarizine...
  38. Dumas G, de Waele C, Hamann K, Cohen B, Negrevergne M, Ulmer E, et al. [Skull vibration induced nystagmus test]. Ann Otolaryngol Chir Cervicofac. 2007;124:173-83 pubmed
    ..To establish during a consensus meeting the fundamental basis, the validity criteria, the main indications and results of the skull vibration induced nystagmus test (SVINT) which explores the vestibule high frequencies...
  39. Ushio M, Murofushi T, Iwasaki S. Subjective visual horizontal in patients with posterior canal benign paroxysmal positional vertigo. Acta Otolaryngol. 2007;127:836-8 pubmed
    ..Patients with posterior canal benign paroxysmal positional vertigo (p-BPPV) could have mild excitation in the vestibular system on the affected side...
  40. Choi K, Oh S, Kim H, Koo J, Cho B, Kim J. Recovery of vestibular imbalances after vestibular neuritis. Laryngoscope. 2007;117:1307-12 pubmed
    ..To determine chronological characteristics of vestibular recovery after vestibular neuritis (VN) by using various clinical parameters...
  41. Murofushi T, Iwasaki S, Ushio M. Recovery of vestibular evoked myogenic potentials after a vertigo attack due to vestibular neuritis. Acta Otolaryngol. 2006;126:364-7 pubmed
    ..Inferior vestibular nerve functions could recover in patients with vestibular neuritis (VN)...
  42. Lehrer J. The use of antiserotonin drugs in the nucleoreticular vestibular syndrome: preliminary observations. Int Tinnitus J. 2004;10:84-6 pubmed
    b>Vestibular neuronitis was described in 1949 and 1952 by Dix and Hallpike...
  43. Yoshida T, Yamamoto M, Nomura T, Ohwada S, Takazawa R, Ikemiyagi Y, et al. [Examination of dynamic body balance using the body tracking test in cases of vestibular neuronitis]. Nihon Jibiinkoka Gakkai Kaiho. 2008;111:617-22 pubmed
    ..The objects were the patients who were diagnosed as having vestibular neuronitis at the Department of Otolaryngology in Toho University medical center Sakura hospital, and were undergoing ..
  44. Lee H, Kim H, Koo J, Kim J. Progression of acute cochleovestibulopathy into anterior inferior cerebellar artery infarction. J Neurol Sci. 2009;278:119-22 pubmed publisher
    ..AICA infarction should be considered in acute audiovestibular syndrome, especially in aged patients with vascular risk factors, even though the classic brainstem or cerebellar signs are absent...
  45. Newman Toker D, Stanton V, Hsieh Y, Rothman R. Frontline providers harbor misconceptions about the bedside evaluation of dizzy patients. Acta Otolaryngol. 2008;128:601-4 pubmed publisher
  46. Oh S, Kim J, Yang T, Shin B, Jeong S. Cervical and ocular vestibular-evoked myogenic potentials in vestibular neuritis: comparison between air- and bone-conducted stimulation. J Neurol. 2013;260:2102-9 pubmed publisher
    ..In contrast, cVEMP elicited by either ACS or BCV may reflect function of the saccular afferents running in the inferior vestibular nerve...
  47. von Brevern M, Radtke A, Clarke A, Lempert T. Migrainous vertigo presenting as episodic positional vertigo. Neurology. 2004;62:469-72 pubmed
  48. Dieterich M. Dizziness. Neurologist. 2004;10:154-64 pubmed
    ..The functional ranges of the systems overlap, thus permitting them to compensate in part for each other's deficiencies...
  49. Runel Belliard C, Lesprit E, Quinet B, Wiener Vacher S, Saizou C, Grimprel E. [Vestibular neuronitis in a teenager with sickle cell disease. Treatment is urgent]. Arch Pediatr. 2008;15:1423-5 pubmed publisher
    ..They require urgent treatment consisting of exchange transfusion or maintaining optimal hydration associated with blood withdrawal. Treatment of vestibular syndrome in sickle cell disease is urgent...
  50. Pournaras I, Kos I, Guyot J. Benign paroxysmal positional vertigo: a series of eight singular neurectomies. Acta Otolaryngol. 2008;128:5-8 pubmed
    ..We also observed in one patient that BPPV may exist although no nystagmus can be elicited by provocative manoeuvres...
  51. Godemann F, Schabowska A, Naetebusch B, Heinz A, Strohle A. The impact of cognitions on the development of panic and somatoform disorders: a prospective study in patients with vestibular neuritis. Psychol Med. 2006;36:99-108 pubmed
    ..The aim of the present study was to examine the role played by cognitions in the development of panic and somatoform disorders...
  52. Monobe H, Sugasawa K, Murofushi T. The outcome of the canalith repositioning procedure for benign paroxysmal positional vertigo: are there any characteristic features of treatment failure cases?. Acta Otolaryngol Suppl. 2001;545:38-40 pubmed
    ..Patients with idiopathic BPPV showed a significantly higher success rate with CRP than those with secondary BPPV. Patients with secondary BPPV may have quantitatively or qualitatively different lesions than those with idiopathic BPPV...
  53. Macleod D, McAuley D. Vertigo: clinical assessment and diagnosis. Br J Hosp Med (Lond). 2008;69:330-4 pubmed
    ..This review focuses on bedside assessment of vertigo and, by looking at patterns of symptoms and signs, provides guidance as to when to suspect a central cause...