vestibular diseases

Summary

Summary: Pathological processes of the VESTIBULAR LABYRINTH which contains part of the balancing apparatus. Patients with vestibular diseases show instability and are at risk of frequent falls.

Top Publications

  1. Ricci N, Aratani M, Dona F, Macedo C, Caovilla H, Ganança F. A systematic review about the effects of the vestibular rehabilitation in middle-age and older adults. Rev Bras Fisioter. 2010;14:361-71 pubmed
    ..to summarize the results of clinical trials on vestibular rehabilitation (VR) in middle-aged and elderly people with vestibular disorders...
  2. Bechly K, Carender W, Myles J, Sienko K. Determining the preferred modality for real-time biofeedback during balance training. Gait Posture. 2013;37:391-6 pubmed publisher
  3. Bhat A, Davenport J, Cocalis M. Partial anomalous left pulmonary artery along with aortic coarctation in an infant with Kabuki syndrome. Echocardiography. 2012;29:E145-7 pubmed publisher
    ..While coarctation and hypoplastic left heart syndrome are observed in this syndrome, this is the second reported case of aLPA in KS and the first with the forme fruste of left-sided obstruction as well as aLPA in this group of patients...
  4. Grabherr L, Cuffel C, Guyot J, Mast F. Mental transformation abilities in patients with unilateral and bilateral vestibular loss. Exp Brain Res. 2011;209:205-14 pubmed publisher
  5. Hannibal M, Buckingham K, Ng S, Ming J, Beck A, McMillin M, et al. Spectrum of MLL2 (ALR) mutations in 110 cases of Kabuki syndrome. Am J Med Genet A. 2011;155A:1511-6 pubmed publisher
    ..These results are important for understanding the phenotypic consequences of MLL2 mutations for individuals and their families as well as for providing a basis for the identification of additional genes for Kabuki syndrome. ..
  6. Heinze B, Swanepoel D, Hofmeyr L. Systematic review of vestibular disorders related to human immunodeficiency virus and acquired immunodeficiency syndrome. J Laryngol Otol. 2011;125:881-90 pubmed publisher
    ..Disorders of the auditory and vestibular system are often associated with human immunodeficiency virus infection and acquired immunodeficiency syndrome. However, the extent and nature of these vestibular manifestations are unclear...
  7. Lederer D, Grisart B, Digilio M, Benoit V, Crespin M, Ghariani S, et al. Deletion of KDM6A, a histone demethylase interacting with MLL2, in three patients with Kabuki syndrome. Am J Hum Genet. 2012;90:119-24 pubmed publisher
    ..This study identifies KDM6A mutations as another cause of KS and highlights the growing role of histone methylases and histone demethylases in multiple-congenital-anomaly and intellectual-disability syndromes...
  8. Miyake N, Mizuno S, Okamoto N, Ohashi H, Shiina M, Ogata K, et al. KDM6A point mutations cause Kabuki syndrome. Hum Mutat. 2013;34:108-10 pubmed publisher
    ..In this study, we investigated KDM6A in 32 KS patients without an MLL2 mutation. We identified two nonsense mutations and one 3-bp deletion of KDM6A in three KS cases. This is the first report of KDM6A point mutations associated with KS...
  9. Paulussen A, Stegmann A, Blok M, Tserpelis D, Posma Velter C, Detisch Y, et al. MLL2 mutation spectrum in 45 patients with Kabuki syndrome. Hum Mutat. 2011;32:E2018-25 pubmed publisher
    ..0040) when comparing KS patients with an MLL2 mutation compared to patients without a mutation. Our data double the number of MLL2 mutations in KS reported so far and widen the spectrum of MLL2 mutations and disease mechanisms in KS...

More Information

Publications81

  1. Goodworth A, Wall C, Peterka R. A balance control model predicts how vestibular loss subjects benefit from a vibrotactile balance prosthesis. Conf Proc IEEE Eng Med Biol Soc. 2011;2011:1306-9 pubmed publisher
  2. Loughlin P, Mahboobin A, Furman J. Designing vibrotactile balance feedback for desired body sway reductions. Conf Proc IEEE Eng Med Biol Soc. 2011;2011:1310-3 pubmed publisher
    ..Simulation results are provided to illustrate the results...
  3. Allum J, Carpenter M, Horslen B, Davis J, Honegger F, Tang K, et al. Improving impaired balance function: real-time versus carry-over effects of prosthetic feedback. Conf Proc IEEE Eng Med Biol Soc. 2011;2011:1314-8 pubmed publisher
    ..However, the prospect for longer term (>1 week) effects of prosthetic training on balance control remains currently unknown...
  4. Curthoys I. The interpretation of clinical tests of peripheral vestibular function. Laryngoscope. 2012;122:1342-52 pubmed publisher
  5. Li Y, Bögershausen N, Alanay Y, Simsek Kiper P, Plume N, Keupp K, et al. A mutation screen in patients with Kabuki syndrome. Hum Genet. 2011;130:715-24 pubmed publisher
    ..Our results indicate that MLL2 is the major gene for Kabuki syndrome with a wide spectrum of de novo mutations and strongly suggest further genetic heterogeneity...
  6. Micale L, Augello B, Fusco C, Selicorni A, Loviglio M, Silengo M, et al. Mutation spectrum of MLL2 in a cohort of Kabuki syndrome patients. Orphanet J Rare Dis. 2011;6:38 pubmed publisher
    ..Recently mutations in the histone methyl transferase MLL2 gene have been identified as its underlying cause...
  7. Lee B, Kim J, Chen S, Sienko K. Cell phone based balance trainer. J Neuroeng Rehabil. 2012;9:10 pubmed publisher
  8. Banka S, Veeramachaneni R, Reardon W, Howard E, Bunstone S, Ragge N, et al. How genetically heterogeneous is Kabuki syndrome?: MLL2 testing in 116 patients, review and analyses of mutation and phenotypic spectrum. Eur J Hum Genet. 2012;20:381-8 pubmed publisher
    ..Moreover, phenotypic variability of KS suggests that MLL2 testing should be considered even in atypical patients...
  9. Schubert M, Minor L. Vestibulo-ocular physiology underlying vestibular hypofunction. Phys Ther. 2004;84:373-85 pubmed
  10. Uneri A, Polat S. Vestibular rehabilitation with electrotactile vestibular substitution: early effects. Eur Arch Otorhinolaryngol. 2009;266:1199-203 pubmed publisher
    ..In conclusion, these preliminary results demonstrate efficacy of the EVSS in improving patients symptoms and signs and signify the evidence of sensory substitution in the early post-training period. ..
  11. Iwasaki S, McGarvie L, Halmagyi G, Burgess A, Kim J, Colebatch J, et al. Head taps evoke a crossed vestibulo-ocular reflex. Neurology. 2007;68:1227-9 pubmed
    ..These responses probably reflect vestibular function via crossed otolith-ocular pathways...
  12. Smulders Y, Welgampola M, Burgess A, McGarvie L, Halmagyi G, Curthoys I. The n10 component of the ocular vestibular-evoked myogenic potential (oVEMP) is distinct from the R1 component of the blink reflex. Clin Neurophysiol. 2009;120:1567-76 pubmed publisher
    ..n10 is distinguished from R1 by its earlier onset, laterality, modulation by gaze position and dissociation in patient groups. The n10 component evoked by BCV at Fz is not the R1 component of the blink reflex. ..
  13. Lang E, McConn Walsh R. Vestibular function testing. Ir J Med Sci. 2010;179:173-8 pubmed publisher
    ..The vestibular and balance assessment modalities which are available to help optimise the management of vestibular disease are also discussed. ..
  14. Teggi R, Giordano L, Pistorio V, Bussi M. Vestibular function in HIV patients: preliminary report. Acta Otorhinolaryngol Ital. 2006;26:140-6 pubmed
    ..In order to evaluate equilibrium in these patients, a Dynamic Gait Index (DGI) test was performed. Scores were >21 points in 85.7% of Class A patients and decreased in Classes B and C. ..
  15. Scheenstra R, Rijntjes E, Tavy D, Kingma H, Heijerman H. Vestibulotoxicity as a consequence of systemically administered tobramycin in cystic fibrosis patients. Acta Otolaryngol. 2009;129:4-7 pubmed publisher
    ..The results of the questionnaire could not predict the results of ENG with caloric irrigation. Physical examination showed no abnormalities in any patients. No age- or dose-related predictive factors were found. ..
  16. Whitney S, Jacob R, Sparto P, Olshansky E, Detweiler Shostak G, Brown E, et al. Acrophobia and pathological height vertigo: indications for vestibular physical therapy?. Phys Ther. 2005;85:443-58 pubmed
    ..Vestibular physical therapy may have a role in the management of height phobia related to excessive height vertigo. ..
  17. Welgampola M, Colebatch J. Characteristics and clinical applications of vestibular-evoked myogenic potentials. Neurology. 2005;64:1682-8 pubmed
  18. Herdman S, Hall C, Schubert M, Das V, Tusa R. Recovery of dynamic visual acuity in bilateral vestibular hypofunction. Arch Otolaryngol Head Neck Surg. 2007;133:383-9 pubmed
    ..We theorize that exercises may foster the use of centrally programmed eye movements that could substitute for the vestibulo-ocular reflex. clinicaltrials.gov Identifier: NCT00411216. ..
  19. Goebel J, Sinks B, Parker B, Richardson N, OLOWIN A, Cholewiak R. Effectiveness of head-mounted vibrotactile stimulation in subjects with bilateral vestibular loss: a phase 1 clinical trial. Otol Neurotol. 2009;30:210-6 pubmed publisher
    ..Head-mounted vibrotactile stimulation produced significant improvement in postural stability in subjects with BVL undergoing SOT 5 and 6 testing with no effect on subjective visual vertical during DSVV testing. ..
  20. Whitney S, Marchetti G, Morris L, Sparto P. The reliability and validity of the Four Square Step Test for people with balance deficits secondary to a vestibular disorder. Arch Phys Med Rehabil. 2007;88:99-104 pubmed
    ..The FSST is a reliable and valid tool for measuring the ability to perform multidirectional movements in people with balance deficits secondary to vestibular disorders. ..
  21. Wall C, Kentala E. Effect of displacement, velocity, and combined vibrotactile tilt feedback on postural control of vestibulopathic subjects. J Vestib Res. 2010;20:61-9 pubmed publisher
    ..The improvement by using a predictor is consistent with compensating for a neural processing delay. ..
  22. Weinberg M, Wall C, Robertsson J, O Neil E, Sienko K, Fields R. Tilt determination in MEMS inertial vestibular prosthesis. J Biomech Eng. 2006;128:943-56 pubmed
    ..Positive results in initial testing and a sound theoretical basis for the hardware warrant continued development and testing, which is being conducted at three sites. ..
  23. Faralli M, Ricci G, Molini E, Longari F, Altissimi G, Frenguelli A. Determining subjective visual vertical: dynamic versus static testing. Otol Neurotol. 2007;28:1069-71 pubmed
    ..Given the greater sensitivity of this test, the reduction in perception error time makes it more suitable for revealing false negatives that emerged when using the static test alone. ..
  24. Dozza M, Chiari L, Horak F. Audio-biofeedback improves balance in patients with bilateral vestibular loss. Arch Phys Med Rehabil. 2005;86:1401-3 pubmed
    ..9%, decreased trunk accelerations by 46%+/-9.9%, and increased time spent within +/-1 degrees sway threshold by 195%+/-34.6%. ABF improved stance stability of participants with BVL by increasing the amount of postural corrections. ..
  25. Meli A, Zimatore G, Badaracco C, De Angelis E, Tufarelli D. Vestibular rehabilitation and 6-month follow-up using objective and subjective measures. Acta Otolaryngol. 2006;126:259-66 pubmed
    ..Improvement in objective test results was also seen. These results were stable at follow-up. A correlation was found between different subjective measures, but there was no correlation between subjective and objective measures. ..
  26. Hegeman J, Honegger F, Kupper M, Allum J. The balance control of bilateral peripheral vestibular loss subjects and its improvement with auditory prosthetic feedback. J Vestib Res. 2005;15:109-17 pubmed
    ..Future work will need to determine the effect of a training time on the improvement in balance control using such a prosthetic device and the ideal position and velocity auditory feedback combination. ..
  27. Whitney S, Wrisley D, Furman J. Concurrent validity of the Berg Balance Scale and the Dynamic Gait Index in people with vestibular dysfunction. Physiother Res Int. 2003;8:178-86 pubmed
    ..The Dynamic Gait Index appears to be a more sensitive assessment tool in identifying people with vestibular disorders who are at increased risk for falling, based on currently published criteria. ..
  28. Soler Martín C, Díez Padrisa N, Boadas Vaello P, Llorens J. Behavioral disturbances and hair cell loss in the inner ear following nitrile exposure in mice, guinea pigs, and frogs. Toxicol Sci. 2007;96:123-32 pubmed
    ..This conclusion highlights the potential interest of this toxic effect and offers new animal models in which to decipher its basis...
  29. Polensek S, Sterk C, Tusa R. Screening for vestibular disorders: a study of clinicians' compliance with recommended practices. Med Sci Monit. 2008;14:CR238-242 pubmed
    ..The aim of this study was to examine clinical assessments used by providers in evaluating dizzy patients in outpatient clinics and the emergency department...
  30. Borel L, Harlay F, Lopez C, Magnan J, Chays A, Lacour M. Walking performance of vestibular-defective patients before and after unilateral vestibular neurotomy. Behav Brain Res. 2004;150:191-200 pubmed
    ..They argue for an increased weight of visual reference frame on locomotor functions when vestibular function is unilaterally impaired...
  31. Jung J, Kim J, Chung P, Woo S, Rhee C. Effect of vestibular rehabilitation on dizziness in the elderly. Am J Otolaryngol. 2009;30:295-9 pubmed publisher
    ..Dizziness in the elderly is relatively common, but only a few studies are available. The purpose of this study was to analyze the effect of vestibular rehabilitation on dizziness in elderly patients...
  32. Cohen H. Disability and rehabilitation in the dizzy patient. Curr Opin Neurol. 2006;19:49-54 pubmed
  33. Dozza M, Wall C, Peterka R, Chiari L, Horak F. Effects of practicing tandem gait with and without vibrotactile biofeedback in subjects with unilateral vestibular loss. J Vestib Res. 2007;17:195-204 pubmed
  34. Faralli M, Longari F, Ricci G, Ibba M, Frenguelli A. Influence of extero- and proprioceptive afferents of the plantar surface in determining subjective visual vertical in patients with unilateral vestibular dysfunction. Acta Otorhinolaryngol Ital. 2009;29:245-50 pubmed
  35. Bronstein A, Lempert T. Management of the patient with chronic dizziness. Restor Neurol Neurosci. 2010;28:83-90 pubmed publisher
    ..In contrast, vestibular suppressants or tranquilisers should be reduced or, if possible, stopped. ..
  36. Vichare V, Wall C, Balkwill M, Sienko M. Assessing the effect of vibrotactile feedback during continuous multidirectional platform motion: a frequency domain approach. Conf Proc IEEE Eng Med Biol Soc. 2009;2009:6910-3 pubmed publisher
    ..3 Hz. The lack of a consistent difference among tactor configurations argue in favor of the simplest 4-column configuration during multidirectional continuous surface perturbations...
  37. Polensek S, Tusa R, Sterk C. The challenges of managing vestibular disorders: a qualitative study of clinicians' experiences associated with low referral rates for vestibular rehabilitation. Int J Clin Pract. 2009;63:1604-12 pubmed publisher
    ..To explore clinicians' perspectives influencing the under-diagnosis and management of patients with vestibular impairment (VI)...
  38. Weber K, Macdougall H, Halmagyi G, Curthoys I. Impulsive testing of semicircular-canal function using video-oculography. Ann N Y Acad Sci. 2009;1164:486-91 pubmed publisher
    ..This system is easy to use in a clinical setting, provides an objective measure of the vestibulo-ocular reflex (VOR), and detects both overt and covert catch-up saccades in patients with vestibular loss...
  39. Agrawal Y, Carey J, Della Santina C, Schubert M, Minor L. Disorders of balance and vestibular function in US adults: data from the National Health and Nutrition Examination Survey, 2001-2004. Arch Intern Med. 2009;169:938-44 pubmed publisher
  40. Minasyan A, Keisala T, Zou J, Zhang Y, Toppila E, Syvälä H, et al. Vestibular dysfunction in vitamin D receptor mutant mice. J Steroid Biochem Mol Biol. 2009;114:161-6 pubmed publisher
    ..These data suggest that VDR deficiency in mice is associated with decreased balance function, and may be relevant to poorer balance/posture control in humans with low levels of vitamin D...
  41. Lai C, Shiao A. Chronological changes of hearing in pediatric patients with large vestibular aqueduct syndrome. Laryngoscope. 2004;114:832-8 pubmed
    ..To describe the chronologic changes of hearing in patients with large vestibular aqueduct syndrome (LVAS) and identify the prognostic factors...
  42. Bach Y Rita P. Tactile sensory substitution studies. Ann N Y Acad Sci. 2004;1013:83-91 pubmed
    ..These are common and fully developed devices. The problem is the brain-machine interface (BMI). In this short report, only two substitution systems are discussed, vision and vestibular substitution...
  43. Pau H, Hawker K, Fuchs H, de Angelis M, Steel K. Characterization of a new mouse mutant, flouncer, with a balance defect and inner ear malformation. Otol Neurotol. 2004;25:707-13 pubmed
    ..Furthermore, we asked whether the mutation responsible for the defects was located in the same region of mouse chromosome 4 as several other mouse mutations that we have previously described...
  44. Whitney S, Marchetti G, Schade A, Wrisley D. The sensitivity and specificity of the Timed "Up & Go" and the Dynamic Gait Index for self-reported falls in persons with vestibular disorders. J Vestib Res. 2004;14:397-409 pubmed
    ..Slower scores on the TUG (> 11.1 seconds) and lower scores on the DGI (18) correlated with reports of falls in persons with vestibular dysfunction...
  45. Gutiérrez Márquez A, Jáuregui Renaud K, Viveros Renteria L, Villanueva Padrón L. [Disability due to auditory and vestibular dysfunction in a specialized care center]. Gac Med Mex. 2005;141:105-10 pubmed
    ..To assess the frequency and characteristics of the disability associated with hearing loss and vestibular disease in a Specialized Medical Center of the Mexican Social Security Institute...
  46. Berrettini S, Forli F, Bogazzi F, Neri E, Salvatori L, Casani A, et al. Large vestibular aqueduct syndrome: audiological, radiological, clinical, and genetic features. Am J Otolaryngol. 2005;26:363-71 pubmed
    ..The aim of this study was to analyze the clinical, audiological, radiological, and genetic features of a group of patients affected with large vestibular aqueduct syndrome...
  47. Teggi R, Ceserani N, Luce F, Lazzarin A, Bussi M. Otoneurological findings in human immunodeficiency virus positive patients. J Laryngol Otol. 2008;122:1289-94 pubmed publisher
    ..To investigate vestibular function in human immunodeficiency virus positive subjects...
  48. Weber K, Aw S, Todd M, McGarvie L, Curthoys I, Halmagyi G. Head impulse test in unilateral vestibular loss: vestibulo-ocular reflex and catch-up saccades. Neurology. 2008;70:454-63 pubmed publisher
    ..Bedside HIT identifies subsequent catch-up saccades after the head rotation as indirect signs of VOR deficit...
  49. Mira E. Improving the quality of life in patients with vestibular disorders: the role of medical treatments and physical rehabilitation. Int J Clin Pract. 2008;62:109-14 pubmed
    ..A profile of the compound betahistine and its efficacy on QoL indices in the treatment of Menière's disease and other forms of peripheral vertigo is also presented...
  50. Badke M, Shea T, Miedaner J, Grove C. Outcomes after rehabilitation for adults with balance dysfunction. Arch Phys Med Rehabil. 2004;85:227-33 pubmed
    ..To assess balance, dynamic gait, and dynamic visual acuity outcomes after a vestibular and balance rehabilitation program and to determine which variables were significantly associated with improved balance and ambulation...
  51. Whitney S, Wrisley D. The influence of footwear on timed balance scores of the modified clinical test of sensory interaction and balance. Arch Phys Med Rehabil. 2004;85:439-43 pubmed
  52. Neuhauser H, von Brevern M, Radtke A, Lezius F, Feldmann M, Ziese T, et al. Epidemiology of vestibular vertigo: a neurotologic survey of the general population. Neurology. 2005;65:898-904 pubmed
    ..The purpose of this study was to determine the prevalence and incidence of vestibular vertigo in the general population and to describe its clinical characteristics and associated factors...
  53. Wall C, Kentala E. Control of sway using vibrotactile feedback of body tilt in patients with moderate and severe postural control deficits. J Vestib Res. 2005;15:313-25 pubmed
    ..This trend was found for both SOT 5 and 6, as well as the medium and large MCT. Additionally, during the MCT, the peak deflection and mean recovery time also decreased significantly...
  54. Manckoundia P, Mourey F, Pfitzenmeyer P, Van Hoecke J, Perennou D. Is backward disequilibrium in the elderly caused by an abnormal perception of verticality? A pilot study. Clin Neurophysiol. 2007;118:786-93 pubmed
    ..We hypothesised that backward disequilibrium (BD), defined by a posterior position of the centre of mass with respect to the base of support, could be caused by a backward tilt in the perception of verticality...
  55. Baker K, Brough D, Staecker H. Repair of the vestibular system via adenovector delivery of Atoh1: a potential treatment for balance disorders. Adv Otorhinolaryngol. 2009;66:52-63 pubmed publisher
    ..Additionally, mice treated with atoh1 recover balance function. Currently vestibular diseases have few treatment options and several lines of evidence suggest that regeneration of hair cells may be ..
  56. Horlings C, Küng U, Honegger F, van Engelen B, van Alfen N, Bloem B, et al. Vestibular and proprioceptive influences on trunk movements during quiet standing. Neuroscience. 2009;161:904-14 pubmed publisher
    ..We conclude that there is relative motion between the upper trunk and pelvis during quiet stance and suggest that it may contribute to balance control...
  57. Sienko K, Vichare V, Balkwill M, Wall C. Assessment of vibrotactile feedback on postural stability during pseudorandom multidirectional platform motion. IEEE Trans Biomed Eng. 2010;57:944-52 pubmed publisher
    ..However, the spatial resolution of the tactor displays did not affect subjects' performance, thereby supporting the use of a lower spatial resolution display in future device designs...
  58. Asseman F, Bronstein A, Gresty M. Using vibrotactile feedback of instability to trigger a forward compensatory stepping response. J Neurol. 2007;254:1555-61 pubmed
    ..We conclude that the effectiveness of vibration biofeedback appears limited. Any enhancement of compensatory stepping might be triggered by speeding the decision to step rather than by creating a specific stimulus-response loop...
  59. Jen J. Bilateral vestibulopathy: clinical, diagnostic, and genetic considerations. Semin Neurol. 2009;29:528-33 pubmed publisher
    ..Furthermore, the study of bilateral vestibulopathy may shed light on the pathophysiology of more common vestibular syndromes such as benign recurrent vertigo and vestibular migraine...
  60. McGibbon C, Krebs D, Wolf S, Wayne P, Scarborough D, Parker S. Tai Chi and vestibular rehabilitation effects on gaze and whole-body stability. J Vestib Res. 2004;14:467-78 pubmed
    ..We conclude that GZS is most improved in those who receive VR, but that TC improves WBS and FFS without improving GZS, suggesting patients with VSP can rely on non-gaze related mechanisms to improve postural control...
  61. Sienko K, Balkwill M, Oddsson L, Wall C. Effects of multi-directional vibrotactile feedback on vestibular-deficient postural performance during continuous multi-directional support surface perturbations. J Vestib Res. 2008;18:273-85 pubmed
    ..Therefore, a spatial resolution of 90 degrees (4 columns) seems to be as effective as a spatial resolution of 22.5 degrees (16 columns) for control of standing...
  62. Horak F, Dozza M, Peterka R, Chiari L, Wall C. Vibrotactile biofeedback improves tandem gait in patients with unilateral vestibular loss. Ann N Y Acad Sci. 2009;1164:279-81 pubmed publisher
    ..However, BF did not increase the rate of improvement or retention of improved stability during gait...
  63. Basta D, Singbartl F, Todt I, Clarke A, Ernst A. Vestibular rehabilitation by auditory feedback in otolith disorders. Gait Posture. 2008;28:397-404 pubmed publisher
    ..The results indicate that an auditory feedback rehabilitation program with exercises related to the specific neurotological disease could significantly improve the postural control in patients with otolith disorders...
  64. Rosengren S, McAngus Todd N, Colebatch J. Vestibular-evoked extraocular potentials produced by stimulation with bone-conducted sound. Clin Neurophysiol. 2005;116:1938-48 pubmed
    ..To investigate the origin, whether ocular or extraocular, of the short latency frontal potential (N15) reported by following vestibular stimulation...
  65. Bradshaw A, Curthoys I, Todd M, Magnussen J, Taubman D, Aw S, et al. A mathematical model of human semicircular canal geometry: a new basis for interpreting vestibular physiology. J Assoc Res Otolaryngol. 2010;11:145-59 pubmed publisher
    ..Finally, we mathematically model SCC geometry using Fourier series equations. This work has the potential to reinterpret physiology and pathophysiology in terms of real individual 3D morphology...
  66. Jeong S, Oh S, Kim H, Koo J, Kim J. Vestibular dysfunction in migraine: effects of associated vertigo and motion sickness. J Neurol. 2010;257:905-12 pubmed publisher
    ..The increased tilt suppression may be an adaptive cerebellar mechanism to suppress the hyperactive vestibular system in migraineurs...
  67. Hufner K, Barresi D, Glaser M, Linn J, Adrion C, Mansmann U, et al. Vestibular paroxysmia: diagnostic features and medical treatment. Neurology. 2008;71:1006-14 pubmed publisher
    ..Although VP was described more than 30 years ago by Jannetta and colleagues, we still need more reliable data on its diagnostic features and the efficacy of medical treatment...
  68. Dozza M, Horak F, Chiari L. Auditory biofeedback substitutes for loss of sensory information in maintaining stance. Exp Brain Res. 2007;178:37-48 pubmed
  69. Wagner J, Glaser M, Brandt T, Strupp M. Downbeat nystagmus: aetiology and comorbidity in 117 patients. J Neurol Neurosurg Psychiatry. 2008;79:672-7 pubmed
    ..We reviewed 117 patients to establish whether analysis of a large collective and improved diagnostic means would reduce the number of cases with "idiopathic DBN" and thus change the aetiological spectrum...
  70. Whitney S, Wrisley D, Brown K, Furman J. Is perception of handicap related to functional performance in persons with vestibular dysfunction?. Otol Neurotol. 2004;25:139-43 pubmed
    ..The purpose of this study was to determine if scores between 0 and 30 (mild), 31 and 60 (moderate), and 61 and 100 (severe) on the Dizziness Handicap Inventory (DHI) differentiated a person's functional abilities...
  71. Tyler M, Danilov Y, Bach Y Rita P. Closing an open-loop control system: vestibular substitution through the tongue. J Integr Neurosci. 2003;2:159-64 pubmed
    ..Moreover, postural stability persists for a period of time after removing the vestibular substitution, after which the open-loop instability reappears...
  72. Allum J, Oude Nijhuis L, Carpenter M. Differences in coding provided by proprioceptive and vestibular sensory signals may contribute to lateral instability in vestibular loss subjects. Exp Brain Res. 2008;184:391-410 pubmed