labyrinth diseases


Summary: Pathological processes of the inner ear (LABYRINTH) which contains the essential apparatus of hearing (COCHLEA) and balance (SEMICIRCULAR CANALS).

Top Publications

  1. Minor L. Clinical manifestations of superior semicircular canal dehiscence. Laryngoscope. 2005;115:1717-27 pubmed
    ..To investigate hypotheses about the effects of superior canal dehiscence. To analyze the outcomes in patients who underwent surgical repair of the dehiscence...
  2. Ozgen B, Oguz K, Atas A, Sennaroglu L. Complete labyrinthine aplasia: clinical and radiologic findings with review of the literature. AJNR Am J Neuroradiol. 2009;30:774-80 pubmed publisher
    ..The purpose of this study was to document the imaging findings in a series of patients with CLA, with review of the literature, to better understand this anomaly...
  3. Chen G, Zhang X, Yang F, Mu L. Disposition of nanoparticle-based delivery system via inner ear administration. Curr Drug Metab. 2010;11:886-97 pubmed
    ..The routes and applications for local inner-ear drug delivery will also be mentioned. In closing, this review will give an overview of the potential future development in inner ear administration with nanoparticles...
  4. Hirvonen T, Weg N, Zinreich S, Minor L. High-resolution CT findings suggest a developmental abnormality underlying superior canal dehiscence syndrome. Acta Otolaryngol. 2003;123:477-81 pubmed
    ..Findings on temporal bone CT were analyzed to determine if a developmental abnormality is associated with the syndrome...
  5. Ciuman R. Communication routes between intracranial spaces and inner ear: function, pathophysiologic importance and relations with inner ear diseases. Am J Otolaryngol. 2009;30:193-202 pubmed publisher
    ..They possess a key role in inner ear pressure regulation and fluid homeostasis and are related to inner ear diseases...
  6. Ciuman R. Auditory and vestibular hair cell stereocilia: relationship between functionality and inner ear disease. J Laryngol Otol. 2011;125:991-1003 pubmed publisher
    ..g. Ménière's disease). The anatomical and physiological characteristics of stereocilia are discussed in relation to inner ear malfunctions...
  7. Hansen M, Luxford W. Surgical outcomes in patients with endolymphatic sac tumors. Laryngoscope. 2004;114:1470-4 pubmed
    ..Taken together with other reports, these results suggest that ELSTs are best managed by complete surgical resection. This can generally be accomplished with minimal additional morbidity. ..
  8. Vellin J, Bozorg Grayeli A, Cyna Gorse F, Refass A, Bouccara D, Sterkers O. [Labyrinthine hemorrhage caused by anticoagulant therapy]. Ann Otolaryngol Chir Cervicofac. 2005;122:194-7 pubmed
    ..Labyrinthine hemorrhage should be evoked in the event of sudden sensorineural hearing loss in patients with anticoagulant therapy. MRI is a useful diagnostic tool in this case. ..
  9. Schmal F. [Episodic attacks of vertigo]. HNO. 2003;51:845-58; quiz 859 pubmed

More Information

Publications115 found, 100 shown here

  1. Agrawal S, Parnes L. Transmastoid superior semicircular canal occlusion. Otol Neurotol. 2008;29:363-7 pubmed publisher
    ..The transmastoid approach for superior canal occlusion may not be possible when the dura is low hanging or when there is extensive cranial base dehiscence requiring reconstruction. ..
  2. Zhang L, Sha Y, Dai C. Another etiology for vertigo due to idiopathic lateral semicircular canal bony defect. Auris Nasus Larynx. 2011;38:402-5 pubmed publisher
  3. Pyykko I, Zou J, Zhang W, Zhang Y. Nanoparticle-based delivery for the treatment of inner ear disorders. Curr Opin Otolaryngol Head Neck Surg. 2011;19:388-96 pubmed publisher
    ..Within a few years, when the synthetic vectors have been optimized, the first human drugs/proteins/gene product-based therapies will become available in a phase I study. ..
  4. Mantello E, Moriguti J, Rodrigues Júnior A, Ferrioli E. Vestibular rehabilitation's effect over the quality of life of geriatric patients with labyrinth disease. Braz J Otorhinolaryngol. 2008;74:172-80 pubmed
    ..based on quality of life scales showed that the individuals treated and assessed improved after Vestibular Rehabilitation. we concluded that VR, based on the protocols of Cawthorne and Cooksey, could be beneficial to this population. ..
  5. Sun H, Huang A, Cao S. Current status and prospects of gene therapy for the inner ear. Hum Gene Ther. 2011;22:1311-22 pubmed publisher
    ..We also discuss the progress and prospects of inner ear gene therapy, the advances and shortcomings, with possible solutions in this field of research. ..
  6. Ichijo H. Cupulolithiasis of the horizontal semicircular canal. Eur Arch Otorhinolaryngol. 2012;269:53-6 pubmed publisher
    ..01). These results suggest that vertical and torsional components occur from the horizontal semicircular canal, and the response to ampullopetal bending is more than two times as strong as that to ampullofugal bending. ..
  7. Taylor R, Bradshaw A, Halmagyi G, Welgampola M. Tuning characteristics of ocular and cervical vestibular evoked myogenic potentials in intact and dehiscent ears. Audiol Neurootol. 2012;17:207-18 pubmed publisher
    ..Age-matched oVEMP amplitudes provided excellent separation between SCD and control ears. Although cVEMP amplitudes overlapped between SCD and control ears, better separation was achieved by using a 2-kHz stimulus. ..
  8. Milojcic R, Guinan J, Rauch S, Herrmann B. Vestibular evoked myogenic potentials in patients with superior semicircular canal dehiscence. Otol Neurotol. 2013;34:360-7 pubmed
    ..A probability predictive function from logistic regression of the adjusted cVEMP may be clinically applicable. ..
  9. Brantberg K, Verrecchia L. Testing vestibular-evoked myogenic potentials with 90-dB clicks is effective in the diagnosis of superior canal dehiscence syndrome. Audiol Neurootol. 2009;14:54-8 pubmed publisher
    ..e. estimation of VEMP threshold) is not only time-consuming, but there is also difficulty related to the low signal-to-noise ratio close to the threshold. ..
  10. Fritsch M. Endoscopy of the inner ear. Otolaryngol Clin North Am. 2009;42:1209-22, Table of Contents pubmed publisher
    ..Endoscopic inner ear surgery is a challenging, but potentially very useful method to address inner ear problems. ..
  11. Stephenson M, Saliba I. Prognostic indicators of hearing after complete resection of cholesteatoma causing a labyrinthine fistula. Eur Arch Otorhinolaryngol. 2011;268:1705-11 pubmed publisher
    ..High-resolution preoperative CT-scan is very precise in diagnosing labyrinthine fistula and its radiologic size helps to predict the type of the fistula. ..
  12. Hayashi H, Aoki M, Yamada N, Kuze B, Mizuta K, Ito Y. [Superior semicircular canal dehiscence syndrome treated by calcium phosphate cement canal plugging: a case report]. Nihon Jibiinkoka Gakkai Kaiho. 2011;114:568-72 pubmed
    ..Surgical dehiscence plugging with calcium phosphate cement via the middle fossa resolved vestibular and cochlear symptoms in the more than two years since. ..
  13. Rinaldi V, Portmann D. Vestibular-evoked myogenic potentials after superior semicircular canal obliteration. Rev Laryngol Otol Rhinol (Bord). 2011;132:85-7 pubmed
    ..To analyse vestibular evoked myogenic potentials (VEMPs) characteristics in patients with superior semicircular canal dehiscence syndrome (SCDS) after surgical plugging...
  14. Imhof H, Henk C, Dirisamer A, Czerny C, Gstöttner W. [CT and MRI characteristics of tumours of the temporal bone and the cerebello-pontine angle]. Radiologe. 2003;43:219-26 pubmed
    ..These imaging methods shall be used complementary and may have a great impact for the therapeutic planning. ..
  15. Jung T, Hunter L, Alper C, Paradise J, Roberts J, Park S, et al. Recent advances in otitis media. 9. Complications and sequelae. Ann Otol Rhinol Laryngol Suppl. 2005;194:140-60 pubmed
  16. Fujita N, Yamanaka T, Okamoto H, Hosoi H. [Horizontal canal benign paroxysmal positional vertigo--its affected side and horizontal semicircular canal function]. Nihon Jibiinkoka Gakkai Kaiho. 2005;108:202-6 pubmed
    ..The mechanism causing a difference in caloric test results between canalolithiasis and cupulolithiasis patients thus requires a larger patient population and further examination to be conclusive. ..
  17. Catalano P, Jonnalagadda S, Yu V. Balloon catheter dilatation of Eustachian tube: a preliminary study. Otol Neurotol. 2012;33:1549-52 pubmed publisher
    ..One complication is reported. Endoscopic transnasal ET balloon dilation is a novel approach to treating ET dysfunction. Benefits can be durable up to 3 years. This technique holds much promise and merits further investigation. ..
  18. McKinnon B, Watts T. Subcutaneous emphysema and pneumolabyrinth plus pneumocephalus as complications of middle ear implant and cochlear implant surgery. Ear Nose Throat J. 2013;92:298-300 pubmed
  19. Maiorana C, Staecker H. Advances in inner ear gene therapy: exploring cochlear protection and regeneration. Curr Opin Otolaryngol Head Neck Surg. 2005;13:308-12 pubmed
    ..Gene therapy can protect the inner ear from damage and even restore function through the regeneration of hair cells. ..
  20. García Berrocal J, Ramírez Camacho R, González García J, Verdaguer J, Trinidad A. Does the serological study for viral infection in autoimmune inner ear disease make sense?. ORL J Otorhinolaryngol Relat Spec. 2008;70:16-19; discussion 19-20 pubmed publisher
    ..On the basis of the low efficacy of serological testing and due to the lack of evidence, we do not recommend to carry out serologic studies for viral infection. ..
  21. Crovetto M, Whyte J, Rodriguez O, Lecumberri I, Martinez C, Elexpuru J. Anatomo-radiological study of the Superior Semicircular Canal Dehiscence Radiological considerations of Superior and Posterior Semicircular Canals. Eur J Radiol. 2010;76:167-72 pubmed publisher
    ..We have also analysed the relation between the ossification state of the semicircular canals and the degree of mastoid pneumatization and integrity of Tegmen Tympani...
  22. Nadaraja G, Gurgel R, Fischbein N, Anglemyer A, Monfared A, Jackler R, et al. Radiographic evaluation of the tegmen in patients with superior semicircular canal dehiscence. Otol Neurotol. 2012;33:1245-50 pubmed publisher
    ..The tegmen should be carefully evaluated in patients with SSCD. We have also proposed a new system for radiographically grading the integrity of the tegmen. ..
  23. Topdag M, Iseri M, Gelenli E, Yardimoglu M, Yazir Y, Ulubil S, et al. Effect of intratympanic dexamethasone, memantine and piracetam on cellular apoptosis due to cisplatin ototoxicity. J Laryngol Otol. 2012;126:1091-6 pubmed publisher
    ..05). Dexamethasone and memantine were found superior to piracetam in reducing apoptosis due to cisplatin ototoxicity. Further studies of this subject are needed, incorporating electron microscopy and auditory brainstem response testing. ..
  24. Grasland A, Pouchot J, Hachulla E, Bletry O, Papo T, Vinceneux P. Typical and atypical Cogan's syndrome: 32 cases and review of the literature. Rheumatology (Oxford). 2004;43:1007-15 pubmed
  25. Koo J, Moon I, Shim W, Moon S, Kim J. Value of lying-down nystagmus in the lateralization of horizontal semicircular canal benign paroxysmal positional vertigo. Otol Neurotol. 2006;27:367-71 pubmed
    ..The direction of lying-down nystagmus may help lateralizing the involved ear in horizontal canal benign paroxysmal positional vertigo. ..
  26. Granados O, Meza G. A direct HPLC method to estimate streptomycin and its putative ototoxic derivative, streptidine, in blood serum: application to streptomycin-treated humans. J Pharm Biomed Anal. 2007;43:625-30 pubmed
    ..Therefore, the validated method used can be a valuable tool to measure and follow these compounds in serum of streptomycin-treated patients. ..
  27. McEvoy T, Mikulec A, Armbrecht E, Lowe M. Quantification of hearing loss associated with superior semi-circular canal dehiscence. Am J Otolaryngol. 2013;34:345-9 pubmed publisher
    ..The presence of statistically significant conductive hearing loss in the low frequencies was confirmed for SSCD ears. SSCD may also predispose ears to high frequency sensorineural hearing loss. ..
  28. Brandt T, Baloh R. Rotational vertebral artery occlusion: a clinical entity or various syndromes?. Neurology. 2005;65:1156-7 pubmed
  29. Gershwin M. The mosaic of autoimmunity. Autoimmun Rev. 2008;7:161-3 pubmed publisher
  30. Zhou G, Gopen Q, Kenna M. Delineating the hearing loss in children with enlarged vestibular aqueduct. Laryngoscope. 2008;118:2062-6 pubmed publisher
    ..To explore the clinical characteristics and audiologic outcomes in children with enlarged vestibular aqueduct (EVA)...
  31. Borghi C, Pirodda A. Omega-3 fatty acids: a promising possible treatment for Meniere's disease and other inner ear disorders of unknown origin?. Med Hypotheses. 2012;79:468-70 pubmed publisher
  32. Krombach G, Martiny S, Di Martino E, Westhofen M, Stanzel S, Haage P, et al. T2-weighted turbo spin-echo images, maximum-intensity projections, and three-dimensional volume-rendering for delineation of pathologies and anatomic details of the inner ear. Invest Radiol. 2004;39:756-66 pubmed
    ..However, reconstructions can be valuable for assessing the extent of pathologies and their spatial relation to the anatomic structures. ..
  33. Friedland D, Michel M. Cranial thickness in superior canal dehiscence syndrome: implications for canal resurfacing surgery. Otol Neurotol. 2006;27:346-54 pubmed
    ..Resurfacing methods may have a higher failure rate as the bone graft has reduced mass and maybe prone to resorption. Canal plugging methods may provide a more definitive means of addressing the dehiscent labyrinth than resurfacing. ..
  34. Badaracco C, Labini F, Meli A, De Angelis E, Tufarelli D. Vestibular rehabilitation outcomes in chronic vertiginous patients through computerized dynamic visual acuity and Gaze stabilization test. Otol Neurotol. 2007;28:809-13 pubmed
    ..Moreover, these new parameters permit to completely evaluate vestibular rehabilitation outcomes, adding new information to the generally used tests that only assess vestibulospinal reflex. ..
  35. Fujimoto C, Murofushi T, Sugasawa K, Chihara Y, Ushio M, Yamasoba T, et al. Bilateral vestibulopathy with dissociated deficits in the superior and inferior vestibular systems. Ann Otol Rhinol Laryngol. 2012;121:383-8 pubmed
    ..Idiopathic cases could be categorized into a novel subtype of idiopathic BV. ..
  36. Morvan J, Cathelinaud O, Riviere D, Vatin L, Bousquet F, Verdalle P. [Diagnosis and treatment of post-traumatic perilymphatic fistula: Report of 16 cases]. Rev Laryngol Otol Rhinol (Bord). 2012;133:171-6 pubmed
    ..9%, a loss of tinnitus in 45% and in 27% improvement. The diagnosis must be supported by various diagnostic tests. If evidence in favor of a perilymphatic fistula is credible, surgery has always achieved an excellent functional outcome. ..
  37. Zdebik A, Wangemann P, Jentsch T. Potassium ion movement in the inner ear: insights from genetic disease and mouse models. Physiology (Bethesda). 2009;24:307-16 pubmed publisher
    ..This review focuses on cellular ion transport mechanisms in the stria vascularis that generate the major electrochemical gradients for sensory transduction. ..
  38. Wiatr M, Składzień J, Tomik J, Morawska A, Oles K, Hydzik Sobocińska K. [Vertigo and labyrinthine fistules at the patients operated on chronic otitis media]. Przegl Lek. 2009;66:948-51 pubmed
    ..The fistules were sealed routinely with a fragment of fascia. This procedure proved effective. ..
  39. Cohen S, Roland P, Shoup A, Lowenstein M, Silverstein H, Kavanaugh A, et al. A pilot study of rituximab in immune-mediated inner ear disease. Audiol Neurootol. 2011;16:214-21 pubmed publisher
    ..No significant adverse events were reported. The results of this study suggest further evaluation of rituximab as a treatment for IMED is indicated. ..
  40. Xia L, Yin S, Wang J. Inner ear gene transfection in neonatal mice using adeno-associated viral vector: a comparison of two approaches. PLoS ONE. 2012;7:e43218 pubmed publisher
    ..Transfection efficiency via RWM puncture (58% and 19% for IHCs and OHCs, respectively) was slightly higher, but the difference was not significant. ..
  41. Connor S, Sriskandan N. Imaging of dizziness. Clin Radiol. 2014;69:111-22 pubmed publisher
    ..We review the relevant anatomy, differential diagnosis, and key imaging features of central and peripheral causes of dizziness, as well as the literature for the diagnostic yield in acute and outpatient settings. ..
  42. Nicoucar K, Sakbani K, Vukanovic S, Guyot J. Intralabyrinthine haemorrhage following cocaine consumption. Acta Otolaryngol. 2005;125:899-901 pubmed
    ..The MRI scans were compatible with an intralabyrinthine haemorrhage. To our knowledge, this is the first case of cochleovestibular deficit due to an intralabyrinthine haemorrhage following cocaine consumption. ..
  43. Ayache D, Schmerber S, Lavieille J, Roger G, Gratacap B. [Middle ear cholesteatoma]. Ann Otolaryngol Chir Cervicofac. 2006;123:120-37 pubmed
  44. Bannykh S, Fan X, Hunt G, Moser F. Endolymphatic sac papillary tumor. J Neurooncol. 2008;89:47-8 pubmed publisher
  45. Koike T, Sakamoto C, Sakashita T, Hayashi K, Kanzaki S, Ogawa K. Effects of a perilymphatic fistula on the passive vibration response of the basilar membrane. Hear Res. 2012;283:117-25 pubmed publisher
    ..This model assists in elucidating the mechanisms of hearing loss due to a PLF from the view of dynamics...
  46. Farahmand R, Merchant G, Lookabaugh S, Roosli C, Ulku C, McKenna M, et al. The Audiometric and Mechanical Effects of Partial Ossicular Discontinuity. Ear Hear. 2016;37:206-15 pubmed publisher
    ..The clinical and experimental findings suggest that when encountering larger ABGs at high frequencies when compared with low frequencies, partial ossicular discontinuity should be considered in the differential diagnosis. ..
  47. Abdullah A, Mahmud M, Maimunah A, Zulfiqar M, Saim L, Mazlan R. Preoperative high resolution CT and MR imaging in cochlear implantation. Ann Acad Med Singapore. 2003;32:442-5 pubmed
    ..The above findings contribute significantly to our surgical decisions regarding candidacy for surgery, side selection and surgical technique in cochlear implantation. ..
  48. Mehta D, Statham M, Choo D. Actinomycosis of the temporal bone with labyrinthine and facial nerve involvement. Laryngoscope. 2007;117:1999-2001 pubmed
    ..Prompt tissue diagnosis with suspicion for nonmalignant causes of bone erosive disease can help in implementing appropriate treatment. ..
  49. Brookler K. Illustrative cases of unorthodox tinnitus management. Noise Health. 2013;15:143-7 pubmed publisher
    ..The treatment effects led to a substantial reduction in subjective tinnitus. These findings suggest a potential convergence between bone pathophysiology and some forms of tinnitus. ..
  50. Achache M, Sanjuan Puchol M, Santini L, Lafont B, Cihanek M, Lavieille J, et al. Late pneumolabyrinth after undiagnosed post-traumatic perilymphatic fistula. Case report illustrating the importance of systematic emergency management. Eur Ann Otorhinolaryngol Head Neck Dis. 2013;130:283-7 pubmed publisher
    ..Labyrinth involvement is rare, but there is a risk of perilymphatic rupture that is often underestimated on initial clinical examination due to the predominance of neurological and/or somatic symptoms...
  51. Selmani Z, Ishizaki H, Pyykko I. Can low frequency sound stimulation during posturography help diagnosing possible perilymphatic fistula in patients with sensorineural hearing loss and/or vertigo?. Eur Arch Otorhinolaryngol. 2004;261:129-32 pubmed
    ..In eight cases, Hennebert's sign was present with nystagmus, without PLF. We conclude that pathological responses to the LFS test in posturography can also be encountered in other inner ear diseases without PLF...
  52. Kim M, Choi M, Choi D, Lee M, Kim K, Rhee J, et al. Asymmetric activation of extracellular signal-regulated kinase 1/2 in rat vestibular nuclei by unilateral labyrinthectomy. Brain Res. 2004;1011:238-42 pubmed
    ..These results suggest that unilateral deafferentation of the vestibular system triggers intracellular signal pathways that activate ERK 1/2 in the VN...
  53. Schipper J, Maier W, Rosahl S, Berlis A, Laszig R. [Tumour staged surgery of endolymphatic sac tumors (ELST)]. Laryngorhinootologie. 2004;83:493-500 pubmed
    ..This connection has been observed in 1992 for the first time and confirmed by molecular genetic analyses of the VHL gen. There is no agreement yet concerning diagnostics and therapy...
  54. Carmona S, Nieto D. The specificity and sensitivity of uninhibited COR in labyrinthine-defective patients. Ann N Y Acad Sci. 2005;1039:508-12 pubmed
    ..Therefore, STFH's specificity was 100%. We conclude that the study of the COR through STFH is a simple, useful, and clinically reliable test which should improve our knowledge of the interesting relationship between VOR and COR...
  55. Matteson E, Choi H, Poe D, Wise C, Lowe V, McDonald T, et al. Etanercept therapy for immune-mediated cochleovestibular disorders: a multi-center, open-label, pilot study. Arthritis Rheum. 2005;53:337-42 pubmed
    ..The objective of the current study was to preliminarily evaluate the efficacy of etanercept therapy for IMCVD...
  56. Huang N, Sataloff R. Autoimmune inner ear disease in children. Otol Neurotol. 2011;32:213-6 pubmed publisher
    ..To determine the response to treatment of pediatric patients diagnosed with autoimmune inner ear disease...
  57. McCall A, McKenna M, Merchant S, Curtin H, Lee D. Superior canal dehiscence syndrome associated with the superior petrosal sinus in pediatric and adult patients. Otol Neurotol. 2011;32:1312-9 pubmed publisher
    ..To determine whether pediatric and adult patients with superior canal dehiscence (SCD) at the superior petrosal sinus (SPS) develop superior canal dehiscence syndrome (SCDS)...
  58. Maranhão A, Andrade J, Godofredo V, Matos R, Penido N. Intratemporal complications of otitis media. Braz J Otorhinolaryngol. 2013;79:141-9 pubmed
    ..Otitis media (OM) is considered a potentially severe disease due to the risk of complications...
  59. Antoine M, Hübner C, Arezzo J, Hebert J. A causative link between inner ear defects and long-term striatal dysfunction. Science. 2013;341:1120-3 pubmed publisher
  60. Minor L. Labyrinthine fistulae: pathobiology and management. Curr Opin Otolaryngol Head Neck Surg. 2003;11:340-6 pubmed
  61. Lesinski S. Revision stapedectomy. Curr Opin Otolaryngol Head Neck Surg. 2003;11:347-54 pubmed
  62. Mitka M. Practice parameter: simple maneuver is best therapy for common form of vertigo. JAMA. 2008;300:157-8 pubmed publisher
  63. Haran F, Keshner E. Sensory reweighting as a method of balance training for labyrinthine loss. J Neurol Phys Ther. 2008;32:186-91 pubmed publisher
    ..The purpose of this case report is to describe an intervention that we found to improve balance in a patient with bilateral labyrinthine deficit using a training paradigm based on the sensory reweighting hypothesis...
  64. Youm I, Murowchick J, Youan B. Entrapment and release kinetics of furosemide from pegylated nanocarriers. Colloids Surf B Biointerfaces. 2012;94:133-42 pubmed publisher
    ..These results indicate that pegylated Fur-loaded NCs could be successfully prepared with high EE% and sustained release profile intended for the inner ear drug delivery...
  65. Kataoka Y, Ikezono T, Fukushima K, Yuen K, Maeda Y, Sugaya A, et al. Cochlin-tomoprotein (CTP) detection test identified perilymph leakage preoperatively in revision stapes surgery. Auris Nasus Larynx. 2013;40:422-4 pubmed publisher
    ..When PLF is suspected after stapes surgery, the CTP detection test can be a useful, highly sensitive, and less invasive method for preoperative diagnosis...
  66. Gianna Poulin C, Stallings V, Black F. Eye movement responses to active, high-frequency pitch and yaw head rotations in subjects with unilateral vestibular loss or posterior semicircular canal occlusion. J Vestib Res. 2003;13:131-41 pubmed
    ..Results in some PCP subjects suggested possible minor impairments of horizontal vestibulo-ocular reflexes...
  67. Cherchi M, Huo E, Nelson N, Frankfurt O, Russell E, Raizer J. Gradual hearing loss with bilateral labyrinthine hemorrhage in chronic myelogenous leukemia. Neurology. 2006;67:177-8 pubmed
  68. Dai M, Raphan T, Cohen B. Labyrinthine lesions and motion sickness susceptibility. Exp Brain Res. 2007;178:477-87 pubmed
    ..This provides further evidence that motion sickness is generated through velocity storage, not the direct pathway, and suggests that motion sickness susceptibility can be reduced by reducing the aVOR time constant...
  69. Pirodda A, Brandolini C, Ferri G, Modugno G, Esposti D, Borghi C. Inner ear dysfunction of uncertain origin: a multidisciplinary approach could give something more. Med Hypotheses. 2009;72:188-9 pubmed publisher
  70. Rozengurt N, Lopez I, Chiu C, Kofuji P, Lester H, Neusch C. Time course of inner ear degeneration and deafness in mice lacking the Kir4.1 potassium channel subunit. Hear Res. 2003;177:71-80 pubmed stria vascularis, Kir4.1 helps to generate the cochlear endolymph; and (2). in spiral and vestibular ganglia, Kir4.1 in surrounding glial cells helps to support the spiral and vestibular ganglion neurons and their projecting axons...
  71. Peters T, Monnens L, Cremers C, Curfs J. Genetic disorders of transporters/channels in the inner ear and their relation to the kidney. Pediatr Nephrol. 2004;19:1194-201 pubmed
    ..Based on data from human disorders (with or without mouse counterparts) and mouse models (without human counterparts) this article focuses on the involvement of these transporters/channels in hearing loss...
  72. Tavassolie T, Penninger R, Zuñiga M, Minor L, Carey J. Multislice computed tomography in the diagnosis of superior canal dehiscence: how much error, and how to minimize it?. Otol Neurotol. 2012;33:215-22 pubmed publisher
    ..A threshold of the radiodensity of the bone over the superior semicircular canal may exist that could optimize prediction of an actual SSCD...
  73. Jothi S, Chin C, Rosbe K. Radiology quiz case 1. Autoimmune inner ear disease (AIED). Arch Otolaryngol Head Neck Surg. 2005;131:534, 536-7 pubmed
  74. Chai L, Gao Y, Gu Z, Ni D. [Apoptosis and apoptosis-related genes in experimental autoimmune inner ear disease]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2005;40:561-5 pubmed
    ..To investigate the protein and mRNA expression patterns of apoptosis-related genes, together with evidence of apoptosis, in relation to experimental autoimmune inner ear disease (AIED)...
  75. Dai C, Sha Y, Chi F, Wang Z. [Diagnosis of superior semicircular canal dehiscence syndrome]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2008;43:27-31 pubmed
    ..To better understand superior semicircular canal dehiscence (SSCD) syndrome...
  76. Kim J, Lee H. Inner ear dysfunction due to vertebrobasilar ischemic stroke. Semin Neurol. 2009;29:534-40 pubmed publisher
    ..Here the authors review the keys to the diagnosis of vertigo and hearing loss associated with vertebrobasilar ischemic stroke...
  77. Nomiya S, Cureoglu S, Kariya S, Morita N, Nomiya R, Schachern P, et al. Posterior semicircular canal dehiscence: a histopathologic human temporal bone study. Otol Neurotol. 2010;31:1122-7 pubmed publisher
    ..Posterior semicircular canal dehiscence has been shown to cause ear symptoms...
  78. Park P, Toung J, Smythe P, Telian S, La Marca F. Unilateral sensorineural hearing loss after spine surgery: Case report and review of the literature. Surg Neurol. 2006;66:415-8; discussion 418-9 pubmed
    ..Although multiple etiologies have been identified, infection and idiopathic SNHL are most common. Sudden sensorineural hearing loss after nonotologic noncardiac surgery is highly unusual, particularly after spinal surgery...
  79. Pearce J. Robert Bárány. J Neurol Neurosurg Psychiatry. 2007;78:302 pubmed
  80. Swan E, Mescher M, Sewell W, Tao S, Borenstein J. Inner ear drug delivery for auditory applications. Adv Drug Deliv Rev. 2008;60:1583-99 pubmed publisher
    ..Innovative drug delivery systems to treat various inner ear ailments such as ototoxicity, sudden sensorineural hearing loss, autoimmune inner ear disease, and for preserving neurons and regenerating sensory cells are being explored...
  81. Platt M, Dilwali S, Elackattu A, Parikh J, Stankovic K. Mining immune epitopes in the inner ear. Otolaryngol Head Neck Surg. 2014;150:460-3 pubmed publisher
    ..If validated in future clinical trials, these candidate immune epitopes in the inner ear would be potential novel targets for diagnosis and treatment of some inner ear disorders and the resulting hearing loss. ..
  82. Potyagaylo V, Della Santina C, Minor L, Carey J. Superior canal dehiscence is not due to cephalic displacement of the labyrinth. Ann N Y Acad Sci. 2005;1039:498-502 pubmed
    ..Results showed that neither was the case. Instead, the defect may be in the process of ossification above the superior canal...
  83. Chang J, Kwon B, Han M, Kang H, Chang K. Kaposiform hemangioendothelioma arising from the internal auditory canal. AJNR Am J Neuroradiol. 2006;27:931-3 pubmed
    ..We present a case of Kaposiform hemangioendothelioma in the internal auditory canal that had no differential features on initial MR images and rapidly grew into a huge mass in a few months...
  84. Pirodda A, Brandolini C, Raimondi M, Modugno G. The possible role of proton pump inhibitors of the homeostasis of the inner ear. Med Hypotheses. 2009;72:325-6 pubmed publisher
    ..These considerations, deserving a further study, seem to be based on logical assessment and therefore in our opinion deserve to be kept in mind in trying to define inner ear disorders of uncertain origin...
  85. Pathak S, Hatam L, Bonagura V, Vambutas A. Innate immune recognition of molds and homology to the inner ear protein, cochlin, in patients with autoimmune inner ear disease. J Clin Immunol. 2013;33:1204-15 pubmed publisher
    ..In conclusion, the present studies indicate that fungal exposure can trigger autoimmunity in a subset of susceptible AIED patients. ..
  86. Kuruma T, Nakayama M, Nakano A, Wu M, Inafuku S, Feng G. [Immunohistochemical study for monoamine neurons in the brain of unilateral inner ear impaired rats]. Nihon Jibiinkoka Gakkai Kaiho. 2003;106:1143-51 pubmed
    ..We conclude that inner ear impairment may diminish the ipsilateral amount of monoamines in the brain but not the cotralateral, possibly inducing a vestibular compensation such as an upregulation of monoamine receptors...
  87. Vargas Dĭaz J, Garófalo Gómez N, Rodriguez U, Parra M, Barroso García E, Novoa López L, et al. [Mondini dysplasia: recurrent bacterial meningitis in adolescence]. Rev Neurol. 2004;39:935-9 pubmed
    ..Congenital deformity of the bony labyrinth can be linked to a fistulous tract communicating it with the intracranial subarachnoid space. Mondini deformity is a frequent malformation in congenitally deaf patients...
  88. Wang W, Chi F, Wu L, Lu H. [Normative data and clinical practice of sinusoidal harmonic acceleration test]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2010;45:14-8 pubmed
    ..To establish the normative data of sinusoidal harmonic acceleration test (SHAT) and evaluate the value of clinical application...
  89. Brookler K. Medicine-based evidence: reverse translational ear research recommendations. Int Tinnitus J. 2009;15:139-48 pubmed
  90. Roberts D, Lin H, Bhattacharyya N. Health care practice patterns for balance disorders in the elderly. Laryngoscope. 2013;123:2539-43 pubmed publisher
    ..Characterize health care practice patterns for balance disorders in the elderly...
  91. Richard G. Connexin gene pathology. Clin Exp Dermatol. 2003;28:397-409 pubmed
  92. Tirelli G, Russolo M. 360-Degree canalith repositioning procedure for the horizontal canal. Otolaryngol Head Neck Surg. 2004;131:740-6 pubmed
    ..To evaluate the efficacy of modifications to the standard canalith repositioning procedure (CRP) in the treatment of benign positional vertigo (BPV) of the horizontal semicircular canal (HSC)...