potyvirus

Summary

Summary: A large genus of plant viruses of the family POTYVIRIDAE which infect mainly plants of the Solanaceae. Transmission is primarily by aphids in a non-persistent manner. The type species is potato virus Y.

Top Publications

  1. pmc Kinetic mechanism for the binding of eIF4F and tobacco Etch virus internal ribosome entry site rna: effects of eIF4B and poly(A)-binding protein
    Mateen A Khan
    Department of Chemistry and Biochemistry, Hunter College and Graduate Center of the City University of New York, New York, New York 10065, USA
    J Biol Chem 284:35461-70. 2009
  2. ncbi The HC-pro protein of potato virus Y interacts with NtMinD of tobacco
    Yongsheng Jin
    State Key Laboratory of Agro Biotechnology, China Aricultural University, Beijing, P R China
    Mol Plant Microbe Interact 20:1505-11. 2007
  3. ncbi Molecular dissection of the potato virus Y VPg virulence factor reveals complex adaptations to the pvr2 resistance allelic series in pepper
    Valérie Ayme
    INRA, UR407 Pathologie Végétale, F 84143 Montfavet, France
    J Gen Virol 88:1594-601. 2007
  4. pmc Distribution of fitness and virulence effects caused by single-nucleotide substitutions in Tobacco Etch virus
    Purificación Carrasco
    Instituto de Biología Molecular y Celular de Plantas CSIC UPV, Avenida de los Naranjos s n, 46022 Valencia, Spain
    J Virol 81:12979-84. 2007
  5. pmc Formation of complexes at plasmodesmata for potyvirus intercellular movement is mediated by the viral protein P3N-PIPO
    Taiyun Wei
    Southern Crop Protection and Food Research Centre, Agriculture and Agri Food Canada, London, Ontario, Canada
    PLoS Pathog 6:e1000962. 2010
  6. ncbi Genetic evidence for an essential role for potyvirus CI protein in cell-to-cell movement
    J C Carrington
    Institute of Biological Chemistry, Washington State University, Pullman 99164, USA
    Plant J 14:393-400. 1998
  7. pmc Capsid protein-mediated recruitment of host DnaJ-like proteins is required for Potato virus Y infection in tobacco plants
    Daniel Hofius
    Copenhagen Biocenter, University of Copenhagen, Ole Maaloes Vej 5, DK 2200 Copenhagen N, Denmark
    J Virol 81:11870-80. 2007
  8. doi Cylindrical inclusion protein of potato virus A is associated with a subpopulation of particles isolated from infected plants
    Rasa Gabrenaite-Verkhovskaya
    Department of Applied Chemistry and Microbiology, FIN 00014 University of Helsinki, Finland
    J Gen Virol 89:829-38. 2008
  9. pmc Structural flexibility allows the functional diversity of potyvirus genome-linked protein VPg
    Kimmo I Rantalainen
    Department of Food and Environmental Sciences, University of Helsinki, Finland
    J Virol 85:2449-57. 2011
  10. pmc Epistasis between mutations is host-dependent for an RNA virus
    Jasna Lalić
    Instituto de Biologia Molecular y Celular de Plantas, CSIC UPV, Valencia, Spain
    Biol Lett 9:20120396. 2013

Research Grants

  1. GENETIC ANALYSIS OF RNA VIRUS-HOST INTERACTION
    JAMES CARRINGTON; Fiscal Year: 2006
  2. GENETIC ANALYSIS OF RNA VIRUS-HOST INTERACTION
    JAMES CARRINGTON; Fiscal Year: 2005
  3. GENETIC ANALYSIS OF RNA VIRUS-HOST INTERACTION
    JAMES CARRINGTON; Fiscal Year: 2007
  4. GENETIC ANALYSIS OF RNA VIRUS-HOST INTERACTION
    JAMES CARRINGTON; Fiscal Year: 2004
  5. GENETIC ANALYSIS OF RNA VIRUS-HOST INTERACTION
    JAMES CARRINGTON; Fiscal Year: 2003
  6. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin Hughes; Fiscal Year: 2006
  7. GENETICS OF ALZHEIMER'S DISEASE IN ISRAELI ARABS
    ROBERT FRIEDLAND; Fiscal Year: 2006
  8. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin Hughes; Fiscal Year: 2007
  9. GENETICS OF ALZHEIMER'S DISEASE IN ISRAELI ARABS
    Alan Lerner; Fiscal Year: 2007
  10. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin Hughes; Fiscal Year: 2008

Detail Information

Publications247 found, 100 shown here

  1. pmc Kinetic mechanism for the binding of eIF4F and tobacco Etch virus internal ribosome entry site rna: effects of eIF4B and poly(A)-binding protein
    Mateen A Khan
    Department of Chemistry and Biochemistry, Hunter College and Graduate Center of the City University of New York, New York, New York 10065, USA
    J Biol Chem 284:35461-70. 2009
    ..Poly(A)-binding protein and eIF4B mainly affect the eIF4F/TEV association rate. These results demonstrate the first direct kinetic measurements of translation initiation factor binding to an IRES...
  2. ncbi The HC-pro protein of potato virus Y interacts with NtMinD of tobacco
    Yongsheng Jin
    State Key Laboratory of Agro Biotechnology, China Aricultural University, Beijing, P R China
    Mol Plant Microbe Interact 20:1505-11. 2007
    ....
  3. ncbi Molecular dissection of the potato virus Y VPg virulence factor reveals complex adaptations to the pvr2 resistance allelic series in pepper
    Valérie Ayme
    INRA, UR407 Pathologie Végétale, F 84143 Montfavet, France
    J Gen Virol 88:1594-601. 2007
    ..They provide a better understanding of the variable levels of durability of the resistance conferred by the different pvr2 alleles, and have important consequences for a durable management of the resistances...
  4. pmc Distribution of fitness and virulence effects caused by single-nucleotide substitutions in Tobacco Etch virus
    Purificación Carrasco
    Instituto de Biología Molecular y Celular de Plantas CSIC UPV, Avenida de los Naranjos s n, 46022 Valencia, Spain
    J Virol 81:12979-84. 2007
    ..Here we used site-directed mutagenesis to create a collection of 66 clones of Tobacco etch potyvirus, each carrying a different, randomly chosen, single-nucleotide substitution...
  5. pmc Formation of complexes at plasmodesmata for potyvirus intercellular movement is mediated by the viral protein P3N-PIPO
    Taiyun Wei
    Southern Crop Protection and Food Research Centre, Agriculture and Agri Food Canada, London, Ontario, Canada
    PLoS Pathog 6:e1000962. 2010
    ..Previous genetic and ultrastructural data revealed that the potyvirus cyclindrical inclusion (CI) protein is directly involved in cell-to-cell movement, likely through the formation ..
  6. ncbi Genetic evidence for an essential role for potyvirus CI protein in cell-to-cell movement
    J C Carrington
    Institute of Biological Chemistry, Washington State University, Pullman 99164, USA
    Plant J 14:393-400. 1998
    The potyvirus cylindrical inclusion (CI) protein, an RNA helicase required for genome replication, was analyzed genetically using alanine-scanning mutagenesis...
  7. pmc Capsid protein-mediated recruitment of host DnaJ-like proteins is required for Potato virus Y infection in tobacco plants
    Daniel Hofius
    Copenhagen Biocenter, University of Copenhagen, Ole Maaloes Vej 5, DK 2200 Copenhagen N, Denmark
    J Virol 81:11870-80. 2007
    ..Therefore, we propose that NtCPIPs act as important susceptibility factors during PVY infection, possibly by recruiting heat shock protein 70 chaperones for viral assembly and/or cellular spread...
  8. doi Cylindrical inclusion protein of potato virus A is associated with a subpopulation of particles isolated from infected plants
    Rasa Gabrenaite-Verkhovskaya
    Department of Applied Chemistry and Microbiology, FIN 00014 University of Helsinki, Finland
    J Gen Virol 89:829-38. 2008
    ..The results are discussed in the context of a model for CI-mediated functions...
  9. pmc Structural flexibility allows the functional diversity of potyvirus genome-linked protein VPg
    Kimmo I Rantalainen
    Department of Food and Environmental Sciences, University of Helsinki, Finland
    J Virol 85:2449-57. 2011
    ..Taken together, our experimental data support the features presented in the model and the idea that the functional diversity is attributable to structural flexibility...
  10. pmc Epistasis between mutations is host-dependent for an RNA virus
    Jasna Lalić
    Instituto de Biologia Molecular y Celular de Plantas, CSIC UPV, Valencia, Spain
    Biol Lett 9:20120396. 2013
    ..Understanding the effect of host species in the sign and magnitude of epistasis will provide insights into the evolutionary ecology of infectious diseases and the predictability of viral emergence...
  11. ncbi Point mutations in helper component protease of clover yellow vein virus are associated with the attenuation of RNA-silencing suppression activity and symptom expression in broad bean
    M L M Yambao
    Pathogen Plant Interactions Group, Plant Breeding Science, Graduate School of Agriculture, Hokkaido University, Sapporo, Japan
    Arch Virol 153:105-15. 2008
    Helper component protease (HC-Pro) is a potyvirus-encoded multifunctional protein and a major determinant of symptom expression in a susceptible plant...
  12. doi Recessive resistance to plant viruses
    V Truniger
    Centro de Edafología y Biología Aplicada del Segura CEBAS, Consejo Superior de Investigaciones Cientificas CSIC, Apdo Correos 164, 30100 Espinardo Murcia, Spain
    Adv Virus Res 75:119-59. 2009
    ..We review actual and probable recessive resistance mechanisms, and bring the chapter to a close by summarizing the current state-of-the-art and offering perspectives on potential future developments...
  13. pmc A cysteine-rich plant protein potentiates Potyvirus movement through an interaction with the virus genome-linked protein VPg
    P Dunoyer
    John Innes Centre, Norwich NR4 7UH, United Kingdom
    J Virol 78:2301-9. 2004
    ..The factor, called Potyvirus VPg-interacting protein (PVIP), is a plant-specific protein with homologues in all the species examined, i.e...
  14. pmc Sequential recruitment of the endoplasmic reticulum and chloroplasts for plant potyvirus replication
    Taiyun Wei
    Southern Crop Protection and Food Research Centre, AAFC, 1391 Sandford Street, London, Ontario N5V 4T3, Canada
    J Virol 84:799-809. 2010
    ..that induces the formation of 6K-containing membranous vesicles at endoplasmic reticulum (ER) exit sites for potyvirus genome replication...
  15. pmc Estimation of the number of virus particles transmitted by an insect vector
    Benoit Moury
    Institut National de la Recherche Agronomique, UR407, Pathologie Végétale, F 84143 Montfavet, Cedex, France
    Proc Natl Acad Sci U S A 104:17891-6. 2007
    ..Such narrow bottlenecks emphasize the strength of stochastic events acting on virus populations, and we illustrate, in modeling virus emergence, why estimating this parameter is important...
  16. pmc Turnip mosaic virus RNA replication complex vesicles are mobile, align with microfilaments, and are each derived from a single viral genome
    Sophie Cotton
    Department of Plant Science, McGill University, 21, 111 Lakeshore, Ste Anne de Bellevue, Quebec H9X 3V9, Canada
    J Virol 83:10460-71. 2009
    ..A single-genome origin and presence of protein synthetic machinery components suggest that translation of viral RNA is taking place within the vesicle...
  17. ncbi Structural basis for the substrate specificity of tobacco etch virus protease
    Jason Phan
    Macromolecular Crystallography Laboratory, Center for Cancer Research, NCI Frederick, National Institutes of Health, Frederick, Maryland 21702 1201, USA
    J Biol Chem 277:50564-72. 2002
    ..Analysis of the protein-ligand interactions helps to delineate the structural determinants of substrate specificity and provides guidance for reengineering the enzyme to further improve its utility for biotechnological applications...
  18. pmc Visualization of the interaction between the precursors of VPg, the viral protein linked to the genome of turnip mosaic virus, and the translation eukaryotic initiation factor iso 4E in Planta
    Chantal Beauchemin
    Institut Armand Frappier, Institut National de la Recherche Scientifique, 531 Boulevard des Prairies, Laval, Quebec, Canada H7V 1B7
    J Virol 81:775-82. 2007
    ..VPg-Pro interaction with eIF(iso)4E may be involved in perturbing normal cellular functions, while 6K-VPg-Pro interaction with the translation factor may be needed for viral RNA translation and/or replication...
  19. doi Mutational analysis of the putative pipo of soybean mosaic virus suggests disruption of PIPO protein impedes movement
    R H Wen
    Department of Entomology and Plant Pathology, The University of Tennessee, Knoxville, TN 37996, USA
    Virology 400:1-7. 2010
    The presence of a small open reading frame embedded in the P3 cistron of potyvirus turnip mosaic virus, termed "pipo," was recently discovered. We have now studied the putative pipo of soybean mosaic virus (SMV)...
  20. ncbi Arabidopsis SGS2 and SGS3 genes are required for posttranscriptional gene silencing and natural virus resistance
    P Mourrain
    Laboratoire de Biologie Cellulaire, Institut National de la Recherche Agronomique, Versailles, France
    Cell 101:533-42. 2000
    ..Both sgs2 and sgs3 mutants show enhanced susceptibility to virus, definitively proving that PTGS is an antiviral defense mechanism that can also target transgene RNA for degradation...
  21. pmc Silencing on the spot. Induction and suppression of RNA silencing in the Agrobacterium-mediated transient expression system
    L K Johansen
    Institute of Biological Chemistry, Washington State University, Pullman, Washington 99164-6340, USA
    Plant Physiol 126:930-8. 2001
    ..They also indicate that RNA silencing may be a significant limitation to expression of genes in the Agrobacterium-mediated transient assay but that this limitation can be overcome by using RNA silencing suppressors...
  22. pmc In situ spatial organization of Potato virus A coat protein subunits as assessed by tritium bombardment
    L A Baratova
    N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, Moscow 119899, Russia
    J Virol 75:9696-702. 2001
    ..This is the first model of the three-dimensional structure of a potyvirus coat protein.
  23. ncbi Structural characterization of HC-Pro, a plant virus multifunctional protein
    Celia Plisson
    Universite Rennes I, Unité Mixte de Recherche 6026 CNRS, Campus de Beaulieu, Rennes 35042, Cedex, France
    J Biol Chem 278:23753-61. 2003
    The helper component proteinase (HC-Pro) is a key protein encoded by plant viruses of the genus Potyvirus. HC-Pro is involved in different steps of the viral cycle, aphid transmission, replication, and virus cell-to-cell and systemic ..
  24. doi RNA silencing-mediated resistance to a crinivirus (Closteroviridae) in cultivated sweet potato (Ipomoea batatas L.) and development of sweet potato virus disease following co-infection with a potyvirus
    Jan F Kreuze
    International Potato Center CIP, Applied Biotechnology Laboratory, Germplasm Enhancement and Crop Improvement Division, PO Box 1558, Lima 12, Peru
    Mol Plant Pathol 9:589-98. 2008
    ..complexes when co-infecting with other viruses, including sweet potato feathery mottle virus (SPFMV; genus Potyvirus, family Potyviridae)...
  25. ncbi Inter- and intralineage recombinants are common in natural populations of Turnip mosaic virus
    Zhongyang Tan
    Laboratory of Plant Virology, Faculty of Agriculture, Saga University, Saga 840 8502, Japan
    J Gen Virol 85:2683-96. 2004
    ..It seems that the presence of recombination sites, as well as sequence similarities, may be used to trace the migration and evolution of TuMV...
  26. doi Natural variation and functional analyses provide evidence for co-evolution between plant eIF4E and potyviral VPg
    Carine Charron
    INRA UR1052, Genetics and Breeding of Fruits and Vegetables, Domaine St Maurice, BP94, F 84143 Montfavet, France
    Plant J 54:56-68. 2008
    ..amino acid changes in the central part of the viral genome-linked protein (VPg) are responsible for the potyvirus's ability to overcome eIF4E-mediated resistance...
  27. pmc RTM3, which controls long-distance movement of potyviruses, is a member of a new plant gene family encoding a meprin and TRAF homology domain-containing protein
    Patrick Cosson
    UMR Génomique, Diversité et Pouvoir Pathogène, INRA Université Bordeaux 2, Institut de Biologie Végétale Moléculaire, Villenave D Ornon, France
    Plant Physiol 154:222-32. 2010
    ..Taken together, these observations strongly suggest the RTM proteins might form a multiprotein complex in the resistance mechanism to block the long-distance movement of potyviruses...
  28. ncbi The Arabidopsis eukaryotic initiation factor (iso)4E is dispensable for plant growth but required for susceptibility to potyviruses
    Anne Duprat
    CEA Cadarache DSV DEVM, Laboratoire du Métabolisme Carboné, UMR 163 CNRS CEA, Univ Méditerranée UMR 163, F 13108 Saint Paul lez Durance, Cedex, France
    Plant J 32:927-34. 2002
    ....
  29. doi HC-Pro protein of sugar cane mosaic virus interacts specifically with maize ferredoxin-5 in vitro and in planta
    Yu Qin Cheng
    Department of Plant Pathology and State Key Laboratory of Agro Biotechnology, China Agricultural University, Beijing 100094, PR China
    J Gen Virol 89:2046-54. 2008
    ....
  30. ncbi Transcriptional changes and oxidative stress associated with the synergistic interaction between Potato virus X and Potato virus Y and their relationship with symptom expression
    Alberto García-Marcos
    Departamento de Biología de Plantas, Centro de Investigaciones Biologicas, CSIC, Ramiro de Maeztu 9, 28040 Madrid, Spain
    Mol Plant Microbe Interact 22:1431-44. 2009
    ..Interestingly, expression of genes encoding oxylipin biosynthesis was uniquely upregulated by the synergistic infection. Virus-induced gene silencing of alpha-dioxygenase1 delayed cell death during PVX-PVY infection...
  31. pmc Magnitude and sign epistasis among deleterious mutations in a positive-sense plant RNA virus
    J Lalic
    Instituto de Biologia Molecular y Celular de Plantas, Consejo Superior de Investigaciones Científicas UPV, Valencia, Spain
    Heredity (Edinb) 109:71-7. 2012
    ..In this study we generated 53 Tobacco etch potyvirus genotypes carrying pairs of single-nucleotide substitutions and measured their separated and combined ..
  32. ncbi Selective involvement of members of the eukaryotic initiation factor 4E family in the infection of Arabidopsis thaliana by potyviruses
    Masanao Sato
    Pathogen Plant Interactions Group, Graduate School of Agriculture, Hokkaido University, Sapporo 060 8589, Japan
    FEBS Lett 579:1167-71. 2005
    ..of eIF4E (eIF(iso)4E) were tested for susceptibility to Clover yellow vein virus (ClYVV), a member of the genus Potyvirus. ClYVV accumulated in both inoculated and upper uninoculated leaves of mutant plants lacking eIF(iso)4E, but not ..
  33. ncbi Genetic structure of a population of Potato virus Y inducing potato tuber necrotic ringspot disease in Japan; comparison with North American and European populations
    Tetsuji Ogawa
    Aino Potato Branch, Nagasaki Agriculture and Forestry Experiment Station, Nagasaki 854 0302, Japan
    Virus Res 131:199-212. 2008
    ..Our results suggest that PVY PTNRD was recently introduced into Japan more than once, and has expanded throughout Japan from founder populations...
  34. pmc HSP70 and its cochaperone CPIP promote potyvirus infection in Nicotiana benthamiana by regulating viral coat protein functions
    Anders Hafrén
    Department of Applied Chemistry and Microbiology, University of Helsinki, 00014 Helsinki, Finland
    Plant Cell 22:523-35. 2010
    ..In conclusion, CPIP and HSP70 are crucial components of a distinct translation activity that is associated with potyvirus replication.
  35. ncbi A point mutation in the polymerase of Potato virus Y confers virulence toward the Pvr4 resistance of pepper and a high competitiveness cost in susceptible cultivar
    Berenger Janzac
    INRA, UR407 Pathologie Végétale, R 84140 Montfavet, France
    Mol Plant Microbe Interact 23:823-30. 2010
    To understand why the Pvr4 resistance of pepper against Potyvirus spp...
  36. doi Interaction between potyvirus P3 and ribulose-1,5-bisphosphate carboxylase/oxygenase (RubisCO) of host plants
    Lin Lin
    State Key Laboratory Breeding Base for Zhejiang Sustainable Pest and Disease Control, Institute of Virology and Biotechnology, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310021, China
    Virus Genes 43:90-2. 2011
    ..It is possible that the potyvirus P3 protein affects the normal functions of RubisCO which thus contributes to symptom development.
  37. ncbi Evidence for diversifying selection in Potato virus Y and in the coat protein of other potyviruses
    Benoit Moury
    Station de Pathologie Vegetale, Institut National de la Recherche Agronomique, F 84143 Montfavet cedex, France
    J Gen Virol 83:2563-73. 2002
    ..their biological functions and is essential to an understanding of the evolutionary constraints exerted on the potyvirus genome...
  38. doi A high level of transgenic viral small RNA is associated with broad potyvirus resistance in cucurbits
    Diana Leibman
    Department of Plant Pathology and Weed Sciences, ARO The Volcani Center, Bet Dagan 50250, Israel
    Mol Plant Microbe Interact 24:1220-38. 2011
    ..Transgenic cucumber and melon lines harboring a hairpin construct of the Zucchini yellow mosaic potyvirus (ZYMV) HC-Pro gene accumulated different levels of t-siRNA (6 to 44% of total siRNA) and exhibited resistance to ..
  39. doi Helper component-proteinase (HC-Pro) protein of Papaya ringspot virus interacts with papaya calreticulin
    Wentao Shen
    Key Biotechnology Laboratory for Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology ITBB, Chinese Academy of Tropical Agriculture Sciences CATAS, 4 Xueyuan Road, Haikou, 571101, China
    Mol Plant Pathol 11:335-46. 2010
    ....
  40. ncbi Characterisation of Potato virus Y nnp strain inducing veinal necrosis in pepper: a naturally occurring recombinant strain of PVY
    A Fanigliulo
    Dipartimento di Biologia, Difesa e Biotecnologie Agro Forestali, Universita degli Studi della Basilicata, Potenza, Italy
    Arch Virol 150:709-20. 2005
    ....
  41. ncbi Coordinated and selective recruitment of eIF4E and eIF4G factors for potyvirus infection in Arabidopsis thaliana
    Valerie Nicaise
    Interactions Plante Virus IPV, UMR 1090, INRA Bordeaux 2, BP 81, F 33883 Villenave d Ornon, France
    FEBS Lett 581:1041-6. 2007
    ..analyses of Arabidopsis mutants knocked-out for At-eIF4G genes showed that eIF4G factors are indispensable for potyvirus infection...
  42. pmc Adaptation of tobacco etch potyvirus to a susceptible ecotype of Arabidopsis thaliana capacitates it for systemic infection of resistant ecotypes
    Jasna Lalić
    Instituto de Biologia Molecular y Celular de Plantas, Consejo Superior de Investigaciones Científicas UPV, 46022 Valencia, Spain
    Philos Trans R Soc Lond B Biol Sci 365:1997-2007. 2010
    ..However, empirical tests of this hypothesis are scarce. Arabiodpsis thaliana--tobacco etch potyvirus (TEV) provides an experimentally suitable pathosystem to explore the interplay between genetic variation in host'..
  43. ncbi Biochemical and genetic evidence for interactions between potato A potyvirus-encoded proteins P1 and P3 and proteins of the putative replication complex
    A Merits
    Viikki Biocenter, University of Helsinki, Helsinki, FIN 00014, Finland
    Virology 263:15-22. 1999
    Interactions of the first and third proteins (P1 and P3) of the potato A potyvirus (PVA) with the other six main proteins of PVA were studied using Escherichia coli-expressed recombinant proteins in two in vitro interaction assays and a ..
  44. doi Involvement of the cylindrical inclusion (CI) protein in the overcoming of an eIF4E-mediated resistance against Lettuce mosaic potyvirus
    Anas Abdul-Razzak
    Interactions Plante Virus, UMR GDPP 1090, INRA Université de Bordeaux 2, BP 81, F 33883 Villenave d Ornon, France
    Mol Plant Pathol 10:109-13. 2009
    ..Site-directed mutagenesis pinpointed a key role of the amino acid at position 621 in the virulence. This is the first example of the involvement of a potyviral CI protein in the breaking of an eIF4E-mediated resistance...
  45. ncbi Interaction of the viral protein genome linked of turnip mosaic potyvirus with the translational eukaryotic initiation factor (iso) 4E of Arabidopsis thaliana using the yeast two-hybrid system
    S Wittmann
    Centre de Recherche en Virologie, Institut Armand Frappier, Ville de Laval, Quebec, Canada
    Virology 234:84-92. 1997
    ..order to identify proteins that interact with the viral protein genome linked (VPg)-proteinase of turnip mosaic potyvirus. The screen allowed the isolation of four candidate cDNA clones...
  46. ncbi A natural recessive resistance gene against potato virus Y in pepper corresponds to the eukaryotic initiation factor 4E (eIF4E)
    Sandrine Ruffel
    Genetics and Breeding of Fruits and Vegetable, Dom St Maurice, BP94, F 84143 Montfavet
    Plant J 32:1067-75. 2002
    ..Several lines of evidence indicate that interaction between the potyvirus genome-linked protein (VPg) and eIF4E are important for virus infectivity, suggesting that the recessive ..
  47. pmc The eukaryotic translation initiation factor 4E controls lettuce susceptibility to the Potyvirus Lettuce mosaic virus
    Valerie Nicaise
    Interactions Plante Virus, Institut de Biologie Végétale Moléculaire, Institut National de la Recherche Agronomique, boite postale 81, F 33883 Villenave d Ornon Cedex, France
    Plant Physiol 132:1272-82. 2003
    ..Lactuca sativa) that are susceptible, tolerant, or resistant to infection by Lettuce mosaic virus (LMV; genus Potyvirus) were cloned and sequenced...
  48. ncbi Interaction of VPg-Pro of turnip mosaic virus with the translation initiation factor 4E and the poly(A)-binding protein in planta
    Simon Léonard
    Institut National de la Recherche Scientifique, Institut Armand Frappier, 531 Boulevard des Prairies, Laval, Quebec, Canada H7V 1B7
    J Gen Virol 85:1055-63. 2004
    ..Direct interaction between VPg-Pro and PABP was shown by an ELISA-based binding assay. These experiments suggest that a multi-protein complex may form around VPg-Pro of TuMV...
  49. pmc Biogenesis of cytoplasmic membranous vesicles for plant potyvirus replication occurs at endoplasmic reticulum exit sites in a COPI- and COPII-dependent manner
    Taiyun Wei
    Southern Crop Protection and Food Research Centre, AAFC, 1391 Sandford Street, London, Ontario N5V 4T3, Canada
    J Virol 82:12252-64. 2008
    ..Previously, a 6-kDa potyvirus membrane protein (6K) was shown to interact with the endoplasmic reticulum (ER) and to induce the formation of ..
  50. ncbi Spatial analysis of arabidopsis thaliana gene expression in response to Turnip mosaic virus infection
    Chunling Yang
    Department of Plant Pathology, Iowa State University, Ames, Iowa 50011, USA
    Mol Plant Microbe Interact 20:358-70. 2007
    ..The functions of these downregulated genes are consistent with viral symptoms, such as chlorosis and stunted growth, providing new insight into mechanisms of pathogenesis...
  51. ncbi The potyvirus recessive resistance gene, sbm1, identifies a novel role for translation initiation factor eIF4E in cell-to-cell trafficking
    Zhihuan Gao
    John Innes Centre, Norwich Research Park, Colney, Norwich NR4 7UH, UK
    Plant J 40:376-85. 2004
    ..the eukaryotic translation initiation factor, eIF4E, as a susceptibility factor required for infection with the Potyvirus, Pea seed-borne mosaic virus...
  52. ncbi The coat and cylindrical inclusion proteins of a potyvirus are associated with connections between plant cells
    E Rodriguez-Cerezo
    Centro Nacional de Biotecnologia CSIC, Madrid, Spain
    Virology 236:296-306. 1997
    ....
  53. pmc Intrinsic disorder in Viral Proteins Genome-Linked: experimental and predictive analyses
    Eugenie Hebrard
    UMR 1097 Résistance des Plantes aux Bio agresseurs, IRD, CIRAD, Universite de Montpellier II, BP 64501, 34394 Montpellier Cedex 5, France
    Virol J 6:23. 2009
    ..To date, structural data are still limited to small picornaviral VPgs. Recently three phytoviral VPgs were shown to be natively unfolded proteins...
  54. ncbi Potyvirus terminal protein VPg, effector of host eukaryotic initiation factor eIF4E
    R Grzela
    Institute of Biochemistry and Biophysics IBB, Polish Academy of Sciences, Warsaw, Poland
    Biochimie 88:887-96. 2006
    b>Potyvirus RNA contains at the 5' end a covalently linked virus-encoded protein VPg, which is required for virus infectivity...
  55. ncbi An unusual structure at one end of potato potyvirus particles
    Lesley Torrance
    Scottish Crop Research Institute, Invergowrie, Dundee DD2 5DA, UK
    J Mol Biol 357:1-8. 2006
    ..Our results show that some of the potyvirus particles contain a protruding tip at one end of the virus particles, which is presumably associated with the 5'-..
  56. ncbi Discussion paper: The naming of Potato virus Y strains infecting potato
    R P Singh
    Potato Research Centre, Agriculture and Agri Food Canada, New Brunswick, Canada
    Arch Virol 153:1-13. 2008
    ..A more systematic investigation and characterization of PVY from potato at the biological and molecular levels should eventually result in a biologically meaningful genetic strain concept...
  57. doi Molecular characterization and detection of recombinant isolates of potato virus Y from China
    Xinxi Hu
    Hunan Provincial Engineering Research Center for Potatoes, College of Horticulture and Landscape, Hunan Agricultural University, Changsha, Hunan 410128, China
    Arch Virol 154:1303-12. 2009
    ..Further analysis of these samples using enzyme-linked immunosorbent assay and bioassay revealed that 'HN2' possesses a PVY(O) serotype, a PVY(N) pathotype in tobacco and a PVY(NTN) pathotype in potato...
  58. pmc Phosphorylation of the potyvirus capsid protein by protein kinase CK2 and its relevance for virus infection
    Konstantin I Ivanov
    Institute of Biotechnology, University of Helsinki, FIN 00014 Helsinki, Finland
    Plant Cell 15:2124-39. 2003
    ..These results suggest that the phosphorylation of PVA CP by CK2 plays an important regulatory role in virus infection...
  59. ncbi HcPro, a multifunctional protein encoded by a plant RNA virus, targets the 20S proteasome and affects its enzymic activities
    Lionel Ballut
    UMR 1095 ASP INRA Université Blaise Pascal, Campus des Cézeaux, 24 avenue des Landais, 63177 Aubiere Cedex, France
    J Gen Virol 86:2595-603. 2005
    ..evidence that a plant virus protein, the helper component-proteinase (HcPro) of Lettuce mosaic virus (LMV; genus Potyvirus), interferes with the 20S proteasome ribonuclease is reported here...
  60. ncbi Application of game theory to the interaction between plant viruses during mixed infections
    Susana Martin
    Instituto de Biología Molecular y Celular de Plantas CSIC UPV, 46022 Valencia, Spain
    J Gen Virol 90:2815-20. 2009
    ..Cauliflower mosaic caulimovirus (CaMV) has often been found in mixed infections with turnip mosaic potyvirus (TuMV) in plants of the genus Brassica...
  61. doi The determinant of potyvirus ability to overcome the RTM resistance of Arabidopsis thaliana maps to the N-terminal region of the coat protein
    V Decroocq
    UMR GDPP, INRA Université Bordeaux II, IBVM, Centre INRA de Bordeaux, BP 81, 33883 Villenave d Ornon Cedex France
    Mol Plant Microbe Interact 22:1302-11. 2009
    ..Taken together, these findings demonstrate that the potyvirus CP N-terminal region determines the outcome of the interaction with the RTM-mediated resistance.
  62. ncbi Genomic variability in Potato potyvirus Y (PVY): evidence that PVY(N)W and PVY(NTN) variants are single to multiple recombinants between PVY(O) and PVY(N) isolates
    L Glais
    UMR BiO3P, INRA, Station de Pathologie Vegetale, Rennes Le Rheu, France
    Arch Virol 147:363-78. 2002
    ..Nevertheless, multiple recombination events observed in the PVY(NTN) genome may play a role in the latter phenomenon...
  63. pmc Functional dissection of naturally occurring amino acid substitutions in eIF4E that confers recessive potyvirus resistance in plants
    Inhwa Yeam
    Department of Plant Breeding and Genetics, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY 14853, USA
    Plant Cell 19:2913-28. 2007
    ..Overexpression of the Capsicum-eIF4E protein containing the G107R amino acid substitution in Solanum lycopersicum indicated that this polymorphism alone is sufficient for the acquisition of resistance against several TEV strains...
  64. doi The Tobacco etch virus P3 protein forms mobile inclusions via the early secretory pathway and traffics along actin microfilaments
    Xiaoyan Cui
    College of Plant Protection, Northwest A and F University, Yangling, Shaanxi 712100, P R China
    Virology 397:56-63. 2010
    ..Taken together, these data support previous suggestions that P3 may play dual roles in virus movement and replication...
  65. doi Role of plant virus movement proteins
    Michael Taliansky
    Scottish Crop Research Institute, Invergowrie, Dundee, DD2 5DA, UK
    Methods Mol Biol 451:33-54. 2008
    ..In this review, we focus on the functions and properties of different classes of MPs encoded by RNA containing plant viruses...
  66. ncbi Fluorescent labelling reveals spatial separation of potyvirus populations in mixed infected Nicotiana benthamiana plants
    Christof Dietrich
    Institute of Plant Diseases and Plant Protection, University of Hannover, Herrenhauser Str 2, 30419 Hannover, Germany
    J Gen Virol 84:2871-6. 2003
    ..Plants infected by any of the PVX/potyvirus combinations exhibited synergistic symptoms and large numbers of cells were doubly infected...
  67. ncbi Rapid diagnosis of plant virus diseases by transmission electron microscopy
    Bernd Zechmann
    University of Graz, Institute of Plant Sciences, Schubertstrasse 51, 8010 Graz, Austria
    J Virol Methods 162:163-9. 2009
    ..These methods will contribute towards a rapid and clear identification of virus diseases of plants and will be useful for diagnostic purposes in agriculture and in plant phytopathology...
  68. ncbi Comparisons of the genetic structure of populations of Turnip mosaic virus in West and East Eurasia
    Kenta Tomimura
    Laboratory of Plant Virology, Faculty of Agriculture, Saga University, Saga 840 8502, Japan
    Virology 330:408-23. 2004
    ..These subpopulations seem to have evolved independently from the ancestral European population, and their genetic structure probably reflects founder effects...
  69. ncbi Mapping of viral genomic regions important in cross-protection between strains of a potyvirus
    Jari P T Valkonen
    Department of Plant Biology, Genetics Centre, SLU, Uppsala, Sweden
    Mol Plant Microbe Interact 15:683-92. 2002
    Cross-protection was tested between potato and tobacco strains of Potato virus A, a member of the genus Potyvirus (PVA), in tobacco plants. Cross-protection was effective only at the initiation of infection...
  70. ncbi Production of strain specific antibodies against a synthetic polypeptide corresponding to the N-terminal region of the plum pox potyvirus coat protein
    A Crescenzi
    Dipartimento di Biologia, Difesa e Biotecnologie Argo Forestali, Universita degli Studi della Basilicata, Potenza, Italy
    J Virol Methods 69:181-9. 1997
    Comparison of the predicted coat protein amino acid sequence of the 'sweet cherry' strain of plum pox potyvirus (PPV-SwC) with the corresponding regions of several other PPV strains indicated that the main differences are in the N-..
  71. ncbi Strains of Turnip mosaic potyvirus as defined by the molecular analysis of the coat protein gene of the virus
    F Sanchez
    Departamento de Biotecnologia, INIA, Autopista A 6, Km 7, Madrid 28040, Spain
    Virus Res 94:33-43. 2003
    Turnip mosaic virus (TuMV) is a member of the potyvirus genus with a wide host range and highly variable in its biological characteristics...
  72. pmc Genetic diversity of the ordinary strain of Potato virus Y (PVY) and origin of recombinant PVY strains
    Alexander V Karasev
    Department of PSES, University of Idaho, Moscow, ID 83843, USA
    Phytopathology 101:778-85. 2011
    ....
  73. doi HC-Pro, a potyvirus RNA silencing suppressor, cancels cycling of Cucumber mosaic virus in Nicotiana benthamiana plants
    Noriho Fukuzawa
    Plant Molecular Technology Research Group, Research Institute of Genome Based Biofactory, National Institute of Advanced Industrial Science and Technology, 2 17 1 1 Tsukisamuhigashi Toyohira Ku, Sapporo 062 8517, Japan
    Virus Genes 40:440-6. 2010
    The mixed infection of Cucumber mosaic virus (CMV) and a potyvirus has been known to increase CMV titer in Nicotiana benthamiana plants, resulting in synergistic viral symptoms...
  74. doi Complete genome sequence of Brugmansia suaveolens mottle virus, a potyvirus from an ornamental shrub
    Natalia Lucinda
    Departamento de Biologia Celular, Universidade de Brasilia, Brasilia, DF, Brazil
    Arch Virol 155:1729-32. 2010
    Brugmansia suaveolens mottle virus (BsMoV) was the first potyvirus isolated from "angel trumpet" (Brugmansia suaveolens), described in Brazil...
  75. ncbi Assembly of recombinant coat protein of sugarcane streak mosaic virus into potyvirus-like particles
    M Hema
    Department of Virology, College of Biological and Earth Sciences, Sri Venkateswara University, Tirupati 517 502, India
    Indian J Exp Biol 46:793-6. 2008
    ..Observation of purified SCSMV-AP rCP under electron microscope revealed the presence of potyvirus-like particles (PVLPs)...
  76. ncbi Amino acid substitutions within the Cys-rich domain of the tobacco etch potyvirus HC-Pro result in loss of transmissibility by aphids
    C Llave
    Departamento de Biología de Plantas, Centro de Investigaciones Biologicas, CSIC, Madrid, Spain
    Arch Virol 147:2365-75. 2002
    We examined the role of several amino acid residues located at the N-terminus of the tobacco etch potyvirus (TEV) helper component-proteinase (HC-Pro) in virus transmissibility by aphids...
  77. ncbi Molecular characterisation of an isolate of Dasheen mosaic virus from Zantedeschia aethiopica in China and comparisons in the genus Potyvirus
    J Chen
    College of Life Science, Zhejiang University, Hangzhou, China
    Arch Virol 146:1821-9. 2001
    ..The 9991 nucleotide genome was typical of the genus Potyvirus and phylogenetic analysis showed it to be a member of the Bean common mosaic virus subgroup...
  78. doi Cellular localisation of calcium ions during potato hypersensitive response to Potato virus Y
    Katarzyna Otulak
    Department of Botany, Faculty of Agriculture and Biology, Warsaw University of Life Sciences SGGW, ul Nowoursynowska 159, 02 776 Warsaw, Poland katarzyna
    Micron 42:381-91. 2011
    ..The precipitates of calcium antimonate were detected near the nuclear envelope, inside karyolymph and along tracheary elements, especially when virus particles were present inside...
  79. pmc Complete nucleotide sequence of a potato isolate of strain group C of Potato virus Y from 1938
    Annette M Dullemans
    Plant Research International, Part of Wageningen UR University and Research Centre, Wageningen, The Netherlands
    Arch Virol 156:473-7. 2011
    ..This is the first full-length sequence of a PVY (C) isolate from potato that belongs to the C1 phylogenetic subgroup, which was previously thought to exclusively contain non-potato isolates...
  80. ncbi Molecular resolution of a complex of potyviruses infecting solanaceous crops at the centre of origin in Peru
    C Spetz
    Department of Plant Biology and Forest Genetics, Genetics Centre, SLU, PO Box 7080, SE 750 07 Uppsala, Sweden
    J Gen Virol 84:2565-78. 2003
    ..Many potyviruses (genus Potyvirus) that infect these crops were described 20-30 years ago...
  81. doi Stability of Tobacco etch virus infectious clones in plasmid vectors
    Leonor C Bedoya
    Instituto de Biología Molecular y Celular de Plantas CSIC Universidad Politécnica de Valencia, Avenida de los Naranjos, 46022 Valencia, Spain
    Virus Res 149:234-40. 2010
    ..Using the different inocula produced from the three new plasmids the TEV infectivity was also compared. The results showed that agroinoculation is the most effective inoculation method and is where symptoms unfold earlier...
  82. pmc Recessive resistance in Pisum sativum and potyvirus pathotype resolved in a gene-for-cistron correspondence between host and virus
    I E Johansen
    Biotechnology Group, Danish Institute of Agricultural Sciences, Thorvaldsensvej 40, DK 1871 Frederiksberg C, Denmark
    J Virol 75:6609-14. 2001
    Pea seed-borne mosaic potyvirus (PSbMV) isolates are divided into pathotypes P-1, P-2, and P-4 according to their infection profile on a panel of Pisum sativum lines. P...
  83. ncbi Engineering zucchini yellow mosaic potyvirus as a non-pathogenic vector for expression of heterologous proteins in cucurbits
    T Arazi
    ViroGene Limited, Har-Hotzvim, P.O. Box 45010, 91045, Jerusalem, Israel
    J Biotechnol 87:67-82. 2001
    ..A novel attenuated zucchini yellow mosaic potyvirus (AG) was used for the development of an environmentally safe non-pathogenic virus vector...
  84. pmc Cap-independent translation conferred by the 5' leader of tobacco etch virus is eukaryotic initiation factor 4G dependent
    D R Gallie
    Department of Biochemistry, University of California, Riverside, California 92521 0129, USA
    J Virol 75:12141-52. 2001
    ..TEV IRES activity was enhanced moderately by the poly(A)-binding protein. These observations suggest that the TEV IRES directs cap-independent translation through a mechanism that involves eIF4G specifically...
  85. ncbi The I gene of bean: a dosage-dependent allele conferring extreme resistance, hypersensitive resistance, or spreading vascular necrosis in response to the potyvirus Bean common mosaic virus
    C W Collmer
    Department of Biological and Chemical Sciences, Wells College, Aurora, NY 13026, USA
    Mol Plant Microbe Interact 13:1266-70. 2000
    The resistance to the potyvirus Bean common mosaic virus (BCMV) conferred by the I allele in cultivars of Phaseolus vulgaris has been characterized as dominant, and it has been associated with both immunity and a systemic vascular ..
  86. pmc Helper component proteinase of the genus Potyvirus is an interaction partner of translation initiation factors eIF(iso)4E and eIF4E and contains a 4E binding motif
    Marjo Ala-Poikela
    Department of Agricultural Sciences, P O Box 27, FI 00014, University of Helsinki, Finland
    J Virol 85:6784-94. 2011
    The multifunctional helper component proteinase (HCpro) of potyviruses (genus Potyvirus; Potyviridae) shows self-interaction and interacts with other potyviral and host plant proteins...
  87. doi Evolutionary optimization of peptide substrates for proteases that exhibit rapid hydrolysis kinetics
    Kevin T Boulware
    Department of Chemical Engineering, University of California Santa Barbara, 93106, USA
    Biotechnol Bioeng 106:339-46. 2010
    ....
  88. doi Simultaneous equimolar expression of multiple proteins in plants from a disarmed potyvirus vector
    Leonor Bedoya
    Instituto de Biologia Molecular y Celular de Plantas, Consejo Superior de Investigaciones Cientificas Universidad Politecnica de Valencia, Avenida de los Naranjos, 46022 Valencia, Spain
    J Biotechnol 150:268-75. 2010
    ..The technology is based on the replacement of the viral RNA polymerase (NIb) cistron of a potyvirus by a cassette for the coexpression of multiple heterologous proteins...
  89. ncbi The role of the coat protein region in symptom formation on Physalis floridana varies between PVY strains
    Agnes Bukovinszki
    Agricultural Biotechnology Center, Godollo, Hungary
    Virus Res 127:122-5. 2007
    ..The results suggest that symptom determinants may be different even between strains of the same virus species in a particular host...
  90. ncbi Characterization of Potato virus Y (PVY) molecular determinants involved in the vein necrosis symptom induced by PVYN isolates in infected Nicotiana tabacum cv. Xanthi
    Michel Tribodet
    INRA ENSA, Unité mixte de recherche biologie des organismes et des populations appliquée à la protection des plantes BiO3P, Domaine de la Motte BP 35327, F 35653 Le Rheu cedex, France
    J Gen Virol 86:2101-5. 2005
    ..Site-directed mutagenesis was used to confirm that these two HC-Pro residues are involved in the TVN phenotype...
  91. ncbi Potyvirus genome-linked protein (VPg) determines pea seed-borne mosaic virus pathotype-specific virulence in Pisum sativum
    K E Keller
    USDA ARS, Horticultural Crops Research Laboratory, Oregon State University, Corvallis 97330, USA
    Mol Plant Microbe Interact 11:124-30. 1998
    The mechanism of Pisum sativum pathotype-specific resistance to pea seed-borne mosaic potyvirus (PSbMV) was investigated and the coding region determinant of PSbMV virulence was defined...
  92. doi A novel recombinant strain of Potato virus Y suggests a new viral genetic determinant of vein necrosis in tobacco
    Xiaojun Hu
    University of Idaho, Department of PSES, Moscow, ID 83844, United States
    Virus Res 143:68-76. 2009
    ..Taken together, these data suggest that the vein necrosis genetic determinant of PVY in tobacco is complex and includes other element(s), in addition to the C-terminal fragment of HC-Pro...
  93. doi Characterization of a new potyvirus infecting pepper crops in Ecuador
    Berenger Janzac
    Institut National de la Recherche Agronomique, UR 407 Pathologie Végétale, domaine St Maurice BP 94, Montfavet, France
    Arch Virol 153:1543-8. 2008
    Sequencing 2,951 nucleotides of the 3' proximal region of the genome of a potyvirus isolate collected from Capsicum pubescens (rocoto) pepper in Ecuador revealed that this was the first representative of a new species tentatively named ..
  94. ncbi A new approach for the simultaneous differentiation of biological and geographical strains of Potato virus Y by uniplex and multiplex RT-PCR
    Xianzhou Nie
    Potato Research Centre, Agriculture and Agri Food Canada, P O Box 20280, Fredericton, NB, Canada E3B 4Z7
    J Virol Methods 104:41-54. 2002
    ..Primer pairs can be used in a uniplex (single pair of primer) or multiplex (duplex, tetraplex or pentaplex) competitive RT-PCR, allowing simultaneous testing for any combination of PVY(O), EU-PVY(N/NTN), NA-PVY(N) and NA-PVY(NTN)...
  95. pmc Potato virus A genome-linked protein VPg is an intrinsically disordered molten globule-like protein with a hydrophobic core
    Kimmo I Rantalainen
    Department of Applied Chemistry and Microbiology, PO Box 27, FIN 00014, University of Helsinki, Finland
    Virology 377:280-8. 2008
    Genome-linked protein VPg of Potato virus A (PVA; genus Potyvirus) has essential functions in all critical steps of PVA infection, i.e. replication, movement, and virulence...
  96. ncbi Probable geographical grouping of PVY(N) and PVY(NTN) based on sequence variation in P1 and 5'-UTR of PVY genome and methods for differentiating North American PVY(NTN)
    Xianzhou Nie
    Potato Research Centre, Agriculture and Agri Food Canada, Fredericton, Canada
    J Virol Methods 103:145-56. 2002
    ..Thus sequencing of the P1 gene and use of competitive RT-PCR approach could be applicable for determining the possible origin of new occurrences of PVY(NTN) from other geographical regions...
  97. ncbi Mapping tightly linked genes controlling potyvirus infection at the Rsv1 and Rpv1 region in soybean
    M A Gore
    Department of Crop and Soil Environmental Sciences, Virginia Polytechnic Institute and State University, Blacksburg 24061, USA
    Genome 45:592-9. 2002
    ..Isolating and characterizing Rsv1 and Rpv1 are instrumental in providing insight into the molecular mechanism of potyvirus recognition in soybean...
  98. ncbi Characterisation of a potyvirus and a potexvirus from Chinese scallion
    J Che
    Department of Biotechnology, College of Life Sciences, Zhejiang University, Hangzhou, People s Republic of China
    Arch Virol 147:683-93. 2002
    ..The complete sequences of a potyvirus and a potexvirus were determined and these were shown to represent different viruses from any in the databases...
  99. pmc From hypo- to hypersuppression: effect of amino acid substitutions on the RNA-silencing suppressor activity of the Tobacco etch potyvirus HC-Pro
    Clara Torres-Barceló
    Instituto de Biologia Molecular y Celular de Plantas, Consejo Superior de Investigaciones Científicas UPV, 46022 Valencia, Spain
    Genetics 180:1039-49. 2008
    ..Tobacco etch potyvirus (TEV) HC-Pro protein suppresses RNA silencing and participates in aphid-mediated transmission, polyprotein ..
  100. doi Covalent immobilization of tobacco-etch-virus NIa protease: a useful tool for cleavage of the histidine tag of recombinant proteins
    Ana Cristina Puhl
    Centro de Biologia Molecular Estrutural, Departamento de Bioquimica, Universidade Federal de Santa Catarina, 88040 900 Florianopolis, SC, Brazil
    Biotechnol Appl Biochem 53:165-74. 2009
    ....
  101. ncbi Processive degradation of nascent polypeptides, triggered by tandem AGA codons, limits the accumulation of recombinant tobacco etch virus protease in Escherichia coli BL21(DE3)
    Rachel B Kapust
    Protein Engineering Section, National Cancer Institute at Frederick, Frederick, Maryland 21702 1201, USA
    Protein Expr Purif 24:61-70. 2002
    ....

Research Grants26

  1. GENETIC ANALYSIS OF RNA VIRUS-HOST INTERACTION
    JAMES CARRINGTON; Fiscal Year: 2006
    ..model host to address the functions of two cellular compatibility factors that were identified in screens for potyvirus susceptibility mutants...
  2. GENETIC ANALYSIS OF RNA VIRUS-HOST INTERACTION
    JAMES CARRINGTON; Fiscal Year: 2005
    ..model host to address the functions of two cellular compatibility factors that were identified in screens for potyvirus susceptibility mutants...
  3. GENETIC ANALYSIS OF RNA VIRUS-HOST INTERACTION
    JAMES CARRINGTON; Fiscal Year: 2007
    ..model host to address the functions of two cellular compatibility factors that were identified in screens for potyvirus susceptibility mutants...
  4. GENETIC ANALYSIS OF RNA VIRUS-HOST INTERACTION
    JAMES CARRINGTON; Fiscal Year: 2004
    ..model host to address the functions of two cellular compatibility factors that were identified in screens for potyvirus susceptibility mutants...
  5. GENETIC ANALYSIS OF RNA VIRUS-HOST INTERACTION
    JAMES CARRINGTON; Fiscal Year: 2003
    ..model host to address the functions of two cellular compatibility factors that were identified in screens for potyvirus susceptibility mutants...
  6. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin Hughes; Fiscal Year: 2006
    ..abstract_text> ..
  7. GENETICS OF ALZHEIMER'S DISEASE IN ISRAELI ARABS
    ROBERT FRIEDLAND; Fiscal Year: 2006
    ..The ultimate goal of this study is to find new targets (genetic and non-genetic) for therapy. ..
  8. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin Hughes; Fiscal Year: 2007
    ..In addition, by increasing our understanding of the population diversity and evolutionary history of human immune system genes, this research will enhance our knowledge of human immune function in health and disease. ..
  9. GENETICS OF ALZHEIMER'S DISEASE IN ISRAELI ARABS
    Alan Lerner; Fiscal Year: 2007
    ..The ultimate goal of this study is to find new targets (genetic and non-genetic) for therapy. ..
  10. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin Hughes; Fiscal Year: 2008
    ..In addition, by increasing our understanding of the population diversity and evolutionary history of human immune system genes, this research will enhance our knowledge of human immune function in health and disease. ..
  11. GENETICS OF ALZHEIMER'S DISEASE IN ISRAELI ARABS
    ROBERT FRIEDLAND; Fiscal Year: 2008
    ..The ultimate goal of this study is to find new targets (genetic and non-genetic) for therapy. ..
  12. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin Hughes; Fiscal Year: 2009
    ..In addition, by increasing our understanding of the population diversity and evolutionary history of human immune system genes, this research will enhance our knowledge of human immune function in health and disease. ..
  13. GENETICS OF ALZHEIMER'S DISEASE IN ISRAELI ARABS
    ROBERT FRIEDLAND; Fiscal Year: 2009
    ..The ultimate goal of this study is to find new targets (genetic and non-genetic) for therapy. ..
  14. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin Hughes; Fiscal Year: 2000
    ....
  15. Symposium on Alzheimer's Disease in the Middle East
    ROBERT FRIEDLAND; Fiscal Year: 2005
    ..Topics to be covered include dementia, basic science, diagnoses, history, management and treatment, and ethics, with consideration of the unique cultural traditions of Arab and Jewish populations. ..
  16. Cong Intl. Soc Vascular Behavioral & Cognitive Disorders
    ROBERT FRIEDLAND; Fiscal Year: 2005
    ..Our second event will present in one large Congress the most recent advances in the field, including diagnostic and therapeutic developments by internationally recognized opinion leaders. ..
  17. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin Hughes; Fiscal Year: 1999
    ....
  18. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin Hughes; Fiscal Year: 2002
    ....
  19. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin Hughes; Fiscal Year: 2003
    ..abstract_text> ..
  20. Symposium on Alzheimer's Disease in the Middle East
    ROBERT FRIEDLAND; Fiscal Year: 2003
    ..Topics to be covered include dementia, basic science, diagnoses, history, management and treatment, and ethics, with consideration of the unique cultural traditions of Arab and Jewish populations. ..
  21. International Society for Vascular Behavioral Disorders
    ROBERT FRIEDLAND; Fiscal Year: 2003
    ..This meeting will present in one large Congress the most recent advances in the field, including diagnostic and therapeutic developments by internationally recognized opinion leaders. ..
  22. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin Hughes; Fiscal Year: 2004
    ..abstract_text> ..
  23. Gene Duplication and Genome Evolution
    Austin Hughes; Fiscal Year: 2004
    ..5) Examining the role of transposable elements in duplication of genomic segments by testing for nonrandom association between these elements and putatively duplicated blocks in the yeast genome. ..
  24. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin Hughes; Fiscal Year: 2005
    ..abstract_text> ..
  25. GENETICS OF ALZHEIMER'S DISEASE IN ISRAELI ARABS
    ROBERT FRIEDLAND; Fiscal Year: 2005
    ..The ultimate goal of this study is to find new targets (genetic and non-genetic) for therapy. ..
  26. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin L Hughes; Fiscal Year: 2010
    ..In addition, by increasing our understanding of the population diversity and evolutionary history of human immune system genes, this research will enhance our knowledge of human immune function in health and disease. ..