costus

Summary

Summary: A plant genus of the family Costaceae (sometimes classified in Zingiberaceae), order Zingiberales, subclass Zingiberidae, class Liliopsida (monocotyledons). It is a source of SAPONINS and furostanol glycosides.

Top Publications

  1. ncbi Evaluation of the in vitro anticancer, antimicrobial and antioxidant activities of some Yemeni plants used in folk medicine
    R A A Mothana
    Department of Pharmacognosy, Faculty of Pharmacy, Sana a University, Sana a, Yemen
    Pharmazie 64:260-8. 2009
  2. ncbi Snakebites and ethnobotany in the northwest region of Colombia: Part II: neutralization of lethal and enzymatic effects of Bothrops atrox venom
    R Otero
    Programa de Ofidismo, Facultad de Medicina, Universidad de Antioquia, A A 1226, Medellin, Colombia
    J Ethnopharmacol 71:505-11. 2000
  3. ncbi A molecular phylogeny of Costaceae (Zingiberales)
    C D Specht
    Department of Biology, New York University, New York, New York 10003, USA
    Mol Phylogenet Evol 21:333-45. 2001
  4. ncbi Ethnobotanical survey and antibacterial activity of some plants used in Guinean traditional medicine
    F B Magassouba
    Centre de Recherche et de Valorisation des Plantes Médicinales de Dubréka, BP 6411 Conakry, Guinea
    J Ethnopharmacol 114:44-53. 2007
  5. ncbi Antihyperglycemic and hypolipidemic effects of Costus speciosus in alloxan induced diabetic rats
    Jasmin H Bavarva
    Department of Biosciences, Sardar Patel University, Vallabh Vidyanagar 388120, Gujarat, India
    Phytother Res 22:620-6. 2008
  6. ncbi Probing key targets in insulin signaling and adipogenesis using a methanolic extract of Costus pictus and its bioactive molecule, methyl tetracosanoate
    Kusampudi Shilpa
    Centre for Biotechnology, Anna University, Chennai, Tamil Nadu, 600025, India
    Biotechnol Lett 31:1837-41. 2009
  7. ncbi Antidiabetic and antilipidemic effect of eremanthin from Costus speciosus (Koen.)Sm., in STZ-induced diabetic rats
    J Eliza
    Department of Biotechnology, Holy Cross College, Trichy 620002, Tamil Nadu, India
    Chem Biol Interact 182:67-72. 2009
  8. ncbi Costus pictus extracts stimulate insulin secretion from mouse and human islets of Langerhans in vitro
    Altaf Al-Romaiyan
    Diabetes Research Group, King s College London, London, United Kingdom
    Cell Physiol Biochem 26:1051-8. 2010
  9. ncbi Hypoglycemic potential of Morus indica. L and Costus igneus. Nak.--a preliminary study
    Vishalakshi D Devi
    Department of Studies in Food Science and Nutrition, University of Mysore, Manasagangotri, Mysore 570 006, India
    Indian J Exp Biol 46:614-6. 2008
  10. ncbi Screening of Costus speciosus extracts for antioxidant activity
    M A Vijayalakshmi
    Centre for Bio Separation Technology, V IT University, Vellore 14, Tamil Nadu, India
    Fitoterapia 79:197-8. 2008

Scientific Experts

  • Kathleen M Kay
  • Akhila J Shetty
  • God swill Nduka Anyasor
  • Caroline Plessis
  • Bimba N Joshi
  • Nurul AMN Hazalin
  • Jenn M Yost
  • Wolfgang Wanek
  • Thomas Moeslinger
  • Cheryl A Lans
  • G Indrayanto
  • Madan Mohan Pandey
  • Altaf Al-Romaiyan
  • Ramzi A Mothana
  • Madelaine E Bartlett
  • M Placzek
  • R Otero
  • Francisco A B Cunha
  • J Eliza
  • Daisy Pitchai
  • Veeramuthu Duraipandiyan
  • Savarimuthu Ignacimuthu
  • Anthoneth Ndidi Ezejiofor
  • Orish Ebere Orisakwe
  • Pazhanichamy Kalailingam
  • Hongwei Fan
  • Guangyan Li
  • Chinna Nneka Orish
  • Sandhya V G Nair
  • Kripa Krishnan
  • Arjuna B Medagama
  • Anthonet Ndidi Ezejiofor
  • Eevera Tamilmani
  • Rajendran Kaliaperumal
  • Yann Surget-Groba
  • Arul Albert Baskar
  • Aluana G Abreu
  • Shruti Srivastava
  • Manjula Kesavan
  • Chih Ya Wang
  • Ramasamy S Annadurai
  • K Manjula
  • José G M Costa
  • Henrique D M Coutinho
  • Felipe S Ferreira
  • Samuel V Brito
  • Edinardo F F Matias
  • João Marcelo A Braga
  • Lidiane Feitoza
  • J Qiu
  • L Feitoza
  • Yong Qin Chang
  • Raquel Moreira Britto
  • Wanwisa Lijuan
  • Tasqiah Julianti
  • Jaime Niño
  • Nirmala Arul Rayan
  • Omonike O Ogbole
  • Sanjib Bhattacharya
  • Lucindo J Quintans Júnior
  • Omonkhelini J Owolabi
  • Don Trinh Nguyen
  • S Ignacimuthu
  • P Daisy
  • James Eliza
  • Kusampudi Shilpa
  • G Gireesh
  • Amy C Keller
  • Michael Fürnkranz
  • Jasmin H Bavarva
  • A Robinson
  • Vishalakshi D Devi
  • M A Vijayalakshmi
  • Yu Jin Wang
  • F B Magassouba
  • Wenjie Peng
  • Bernadete P da Silva
  • A O Anaga
  • Aloa Machado De Souza
  • N R Vijayalakshmi
  • Shiying Fang
  • A Helen
  • Noriaki Kawano
  • Fei Liu
  • Maohong Xu
  • K Inoue
  • S W Annie Bligh
  • Menik Hettihewa
  • SAKHILA BANU
  • Dequn Wang

Detail Information

Publications77

  1. ncbi Evaluation of the in vitro anticancer, antimicrobial and antioxidant activities of some Yemeni plants used in folk medicine
    R A A Mothana
    Department of Pharmacognosy, Faculty of Pharmacy, Sana a University, Sana a, Yemen
    Pharmazie 64:260-8. 2009
    ..As a result of this work, 12 Yemeni herbs namely Centaurothamus maximus, Costus arabicus, Cupressus sempervirens, Dichrocephala integrifolia, Euphorbia schimperi, Gomphocarpus fruticosus, ..
  2. ncbi Snakebites and ethnobotany in the northwest region of Colombia: Part II: neutralization of lethal and enzymatic effects of Bothrops atrox venom
    R Otero
    Programa de Ofidismo, Facultad de Medicina, Universidad de Antioquia, A A 1226, Medellin, Colombia
    J Ethnopharmacol 71:505-11. 2000
    ..05) were: leaves, branches and stem of Costus lasius (Costaceae); the whole plant of Sida acuta (Malvaceae); rhizomes of Dracontium croatii (Araceae); leaves ..
  3. ncbi A molecular phylogeny of Costaceae (Zingiberales)
    C D Specht
    Department of Biology, New York University, New York, New York 10003, USA
    Mol Phylogenet Evol 21:333-45. 2001
    ..The genus Costus is broadly paraphyletic but Costus subgenus Eucostus K. Schum...
  4. ncbi Ethnobotanical survey and antibacterial activity of some plants used in Guinean traditional medicine
    F B Magassouba
    Centre de Recherche et de Valorisation des Plantes Médicinales de Dubréka, BP 6411 Conakry, Guinea
    J Ethnopharmacol 114:44-53. 2007
    ..Ximenia americana, Annona senegalensis, Cochlospermum tinctorium, Cochlospermum planchonii, Lantana camara, Costus afer, Psidium guajava, Terminalia glaucescens, Uapaca somon and Swartzia madagascariensis...
  5. ncbi Antihyperglycemic and hypolipidemic effects of Costus speciosus in alloxan induced diabetic rats
    Jasmin H Bavarva
    Department of Biosciences, Sardar Patel University, Vallabh Vidyanagar 388120, Gujarat, India
    Phytother Res 22:620-6. 2008
    ..In the present study, the antihyperglycemic, antihyperlipemic and antioxidant potency of an ethanol extract of Costus speciosus root was investigated in alloxan-induced diabetic male (Charles Foster) rats...
  6. ncbi Probing key targets in insulin signaling and adipogenesis using a methanolic extract of Costus pictus and its bioactive molecule, methyl tetracosanoate
    Kusampudi Shilpa
    Centre for Biotechnology, Anna University, Chennai, Tamil Nadu, 600025, India
    Biotechnol Lett 31:1837-41. 2009
    A methanolic extract of Costus pictus (CPME) showed optimum anti-diabetic activity at 100 ng/ml. Bioactivity-guided purification of CPME led to the isolation of methyl tetracosanoate (MT) which showed an optimum glucose uptake at 1 ng/ml...
  7. ncbi Antidiabetic and antilipidemic effect of eremanthin from Costus speciosus (Koen.)Sm., in STZ-induced diabetic rats
    J Eliza
    Department of Biotechnology, Holy Cross College, Trichy 620002, Tamil Nadu, India
    Chem Biol Interact 182:67-72. 2009
    ..b>Costus speciosus is widely used in Indian medicine to treat various diseases. Eremanthin was isolated from C. speciosus...
  8. ncbi Costus pictus extracts stimulate insulin secretion from mouse and human islets of Langerhans in vitro
    Altaf Al-Romaiyan
    Diabetes Research Group, King s College London, London, United Kingdom
    Cell Physiol Biochem 26:1051-8. 2010
    ..Extracts of Costus pictus (CP), a plant belonging to the Costaceae family, are reported to have antidiabetic activity in vivo...
  9. ncbi Hypoglycemic potential of Morus indica. L and Costus igneus. Nak.--a preliminary study
    Vishalakshi D Devi
    Department of Studies in Food Science and Nutrition, University of Mysore, Manasagangotri, Mysore 570 006, India
    Indian J Exp Biol 46:614-6. 2008
    ..The preliminary results suggest that both the plants possess potent hypoglycemic activity...
  10. ncbi Screening of Costus speciosus extracts for antioxidant activity
    M A Vijayalakshmi
    Centre for Bio Separation Technology, V IT University, Vellore 14, Tamil Nadu, India
    Fitoterapia 79:197-8. 2008
    Different parts of Costus speciosus were investigated for their polyphenol content and antioxidant activity.
  11. ncbi Antioxidant activity of costunolide and eremanthin isolated from Costus speciosus (Koen ex. Retz) Sm
    J Eliza
    Department of Biotechnology, Holy Cross College, Trichy 620002, Tamil Nadu, India
    Chem Biol Interact 188:467-72. 2010
    ..was aimed at assessing the antioxidant property of costunolide and eremanthin isolated from a medicinal plant Costus speciosus (Koen ex. Retz) Sm. rhizome. Experimental diabetes was induced by a single dose of STZ (60mg/kg, i.p...
  12. ncbi Normo-glycemic and hypolipidemic effect of costunolide isolated from Costus speciosus (Koen ex. Retz.)Sm. in streptozotocin-induced diabetic rats
    James Eliza
    Department of Biotechnology, Holy Cross College, Trichy 620002, Tamil Nadu, India
    Chem Biol Interact 179:329-34. 2009
    ..Many plants have successfully been used to overcome this problem. Costus speciosus is widely used in Indian medicine to treat various diseases including diabetes...
  13. ncbi Investigations of the methanolic leaf extract of Costus afer. Ker for pharmacological activities in vitro and in vivo
    A O Anaga
    Department of Veterinary Physiology and Pharmacology, University of Nigeria, Nsukka, Enugu State
    Phytomedicine 11:242-8. 2004
    The methanolic leaf extract of Costus afer. Ker (family: Zingiberaceae) was investigated for some pharmacological effects in vivo and in vitro. Brine shrimp lethality test showed that the extract was significantly (p < 0...
  14. ncbi Efficacy of natural diosgenin on cardiovascular risk, insulin secretion, and beta cells in streptozotocin (STZ)-induced diabetic rats
    Pazhanichamy Kalailingam
    Department of Biotechnology, Periyar Maniammai University, Vallam 613403, Tamil Nadu, India
    Phytomedicine 21:1154-61. 2014
    b>Costus igneus, has been prescribed for the treatment of diabetic mellitus in India for several years...
  15. ncbi Cytological and biochemical studies during the progression of alloxan-induced diabetes and possible protection of an aqueous leaf extract of Costus afer
    Anthoneth Ndidi Ezejiofor
    Faculty of Pharmaceutical Sciences, University of Port Harcourt, Rivers State, Nigeria
    Chin J Nat Med 12:745-52. 2014
    Some plants have proven efficacy in the management of diabetes mellitus, of which Costus afer is one...
  16. ncbi The use of complementary and alternative medicines (CAMs) in the treatment of diabetes mellitus: is continued use safe and effective?
    Arjuna B Medagama
    Department of Medicine, University of Peradeniya, Peradeniya, Sri Lanka
    Nutr J 13:102. 2014
    ..Data on safety and efficacy is limited, but the consumption is wide. Crepe ginger (Costus speciosus) and Ivy gourd (Coccinia grandis) are 2 plants used widely in the Asian region for their presumed ..
  17. ncbi The search for new odorants: synthesis of animalic fragrant and musky/ambery compounds
    Caroline Plessis
    Mane S A, Chemistry Research Centre, 620 route de Grasse, F 06620 Le Bar sur Loup, phone 33 4 9309 7000 fax 33 4 9342 5425
    Chem Biodivers 11:1517-39. 2014
    ..such as bicyclic pentanols, glycolates, or tricyclic ketones, and all show interesting notes in the animalic fragrant family: from costus, leathery to ambery and musky scents, making them all attractive for different purposes.
  18. ncbi Anti-inflammatory potential of β-amyrin, a triterpenoid isolated from Costus igneus
    Kripa Krishnan
    Department of Biochemistry, University of Kerala, Kariavattom Campus, Thiruvananthpuram, 695581, Kerala, India
    Inflammopharmacology 22:373-85. 2014
    b>Costus igneus, common name Fiery Costus or Spiral Flag, is a species of herbaceous plant in the Costaceae family. It is cultivated in India for its use in traditional medicine especially for diabetes...
  19. ncbi [Textual research on Costus root (Aucklandia lappa Decne) in the Sheng nong ben cao jing (Shennong's Classic of Materia Medica)]
    Guangyan Li
    School of Pharmacy, West Anhui Health Vocational College, Liu an, 237000, China
    Zhonghua Yi Shi Za Zhi 44:135-7. 2014
    ..Through the textual research of herbal literature, it was found that the costus root in the Sheng nong ben cao jing perhaps was not the plant of Aucklandia lappa Decne of Compositae, but the ..
  20. ncbi Costus afer ker gawl leaves against gentamicin-induced nephrotoxicity in rats
    Anthonet Ndidi Ezejiofor
    Faculty of Pharmacy University of Port Harcourt, Rivers State, Nigeria
    Iran J Kidney Dis 8:310-3. 2014
    The nephroprotective effect of the aqueous extract of Costus afer leaves was evaluated in male albino Wistar rats with gentamicin-induced kidney injury.
  21. ncbi In vitro and in silico evaluation of NF-κB targeted costunolide action on estrogen receptor-negative breast cancer cells--a comparison with normal breast cells
    Daisy Pitchai
    Holy Cross College, PG and Research Department of Biotechnology, Trichy, Tamil Nadu, India
    Phytother Res 28:1499-505. 2014
    ..The present study aims to evaluate the cytotoxic effect of costunolide isolated from Costus speciosus rhizome extract on MDA-MB-231 cells and explore its targeted action in comparison with its action on the ..
  22. pmc Apoptotic and inhibitory effects on cell proliferation of hepatocellular carcinoma HepG2 cells by methanol leaf extract of Costus speciosus
    Sandhya V G Nair
    Department of Environmental Sciences, Faculty of Agriculture, Dalhousie University, Truro, NS, Canada B2N 5E3
    Biomed Res Int 2014:637098. 2014
    b>Costus speciosus is a medicinal plant commonly known as wild ginger distributed in South and Southeast Asian countries. Leaves of this plant are used for ayurvedic treatment regimes in malignancies and mental illness...
  23. ncbi Structure of a homofructosan from Saussurea costus and anti-complementary activity of its sulfated derivatives
    Hongwei Fan
    The MOE Key Laboratory for Standardization of Chinese Medicines and The SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
    Carbohydr Polym 105:152-60. 2014
    ..9kDa, was isolated and characterized from the roots of Saussurea costus. Five sulfated derivatives of APS-W1 with different degrees of sulfation were prepared and they showed strong ..
  24. ncbi Anti-inflammatory and antioxidant activities of Costus afer Ker Gawl. hexane leaf fraction in arthritic rat models
    Godswill Nduka Anyasor
    Department of Biochemistry, Benjamin S Carson School of Medicine, College of Health and Medical Sciences, Babcock University, Ilisan Remo, Ogun State, P M B 21244 Ikeja, Lagos, Nigeria Electronic address
    J Ethnopharmacol 155:543-51. 2014
    b>Costus afer Ker Gawl is an indigenous tropical African medicinal plant used as therapy in the treatment of inflammatory ailments such as rheumatoid arthritis...
  25. ncbi Phytochemical screening, antibacterial activity and in vitro interactions between Costus cf. arabicus L. with UV-A and aminoglycosides
    Francisco A B Cunha
    Laboratório de Microbiologia e Biologia Molecular, Universidade Regional do Cariri, Crato CE, Brazil
    Nat Prod Res 26:380-6. 2012
    In this study, the methanol extracts of of Costus cf. arabicus L. were evaluated for antibacterial activity against multiresistant strains of Escherichia coli and Staphylococcus aureus...
  26. pmc Next generation sequencing and de novo transcriptome analysis of Costus pictus D. Don, a non-model plant with potent anti-diabetic properties
    Ramasamy S Annadurai
    MTP Biology, ITC R and D Centre, Peenya Industrial Area, Bangalore, Karnataka, India
    BMC Genomics 13:663. 2012
    ..A number of plant species are known to possess diabetic control properties. Costus pictus D...
  27. ncbi Free radical scavenging potential of Saussarea costus
    Madan Mohan Pandey
    Pharmacognosy and Ethnopharmacology Division, National Botanical Research Institute, Lucknow 226 001, India
    Acta Pharm 55:297-304. 2005
    Saussurea costus (Falc.) Lipschitz from the family Asteraceae is an important medicinal drug, the roots of which are widely used in folk medicine...
  28. ncbi Orally active hypoglycemic protein from Costus igneus N. E. Br.: an in vitro and in vivo study
    Bimba N Joshi
    Biometry and Nutrition Group, Agharkar Research Institute, Pune 411 004, India
    Biochem Biophys Res Commun 436:278-82. 2013
    ..In the present study, insulin-like protein (ILP) is purified from Costus igneus belonging to family Costaceae from Western ghats of India...
  29. ncbi Permanent genetic resources added to Molecular Ecology Resources Database 1 October 2011-30 November 2011
    Aluana G Abreu
    Molecular Ecology Resources Editorial Office, 6270 University Blvd, Vancouver BC V6T1Z4, Canada
    Mol Ecol Resour 12:374-6. 2012
    ..Loci were developed for the following species: Aglaoctenus lagotis, Costus pulverulentus, Costus scaber, Culex pipiens, Dascyllus marginatus, Lupinus nanus Benth, Phloeomyzus passerini, ..
  30. pmc Evaluation of anti-arthritic potential of the methanolic extract of the aerial parts of Costus speciosus
    Shruti Srivastava
    Department of Pharmacognosy, Teerthanker Mahaveer College of Pharmacy, Teerthanker Mahaveer University, Moradabad, Uttar Pradesh, India
    J Ayurveda Integr Med 3:204-8. 2012
    b>Costus speciosus Koen. (Keu, Crape ginger), an ornamental plant, widely distributed in India is traditionally used as astringent, aphrodisiac, purgative, anthelmintic, depurative, febrifuge and expectorant...
  31. ncbi Effect of Costus igneus stem extract on calcium oxalate urolithiasis in albino rats
    K Manjula
    Department of Biotechnology, Periyar Maniammai University, Tamil Nadu, India
    Urol Res 40:499-510. 2012
    The effects of aqueous and ethanolic extracts of Costus igneus (stem) and isolated compounds lupeol and stigmasterol on calcium oxalate urolithiasis have been studied in male albino Wistar rats...
  32. pmc Antimicrobial activity of sesquiterpene lactones isolated from traditional medicinal plant, Costus speciosus (Koen ex.Retz.) Sm
    Veeramuthu Duraipandiyan
    Department of Botany and Microbiology, Addiriyah Chair for Environmental Studies, College of Science, King Saud University, Riyad, Saudi Arabia
    BMC Complement Altern Med 12:13. 2012
    b>Costus speciosus (Koen ex.Retz.) Sm (Costaceae) is an Indian ornamental plant which has long been used medicinally in traditional systems of medicine. The plant has been found to possess diverse pharmacological activities...
  33. ncbi Synthesis of tamarixetin and isorhamnetin 3-O-neohesperidoside
    Wenjie Peng
    State Key Laboratory of Catalyst, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China
    Carbohydr Res 340:1682-8. 2005
    Two isomeric flavonol 3-O-glycosides, tamarixetin and isorhamnetin 3-O-neohesperidoside (1 and 2), were synthesized. The natural product from Costus spicatus assigned as the former compound is revised to the latter structure.
  34. ncbi Restricted gene flow within and between rapidly diverging Neotropical plant species
    Yann Surget-Groba
    Key Laboratory of Tropical Forest Ecology, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Mengla, Menglun, Yunnan, 666303, China
    Mol Ecol 22:4931-42. 2013
    ..Here, we document patterns of gene flow within and between two members of a rapid Neotropical species radiation, Costus pulverulentus and Costus scaber (Costaceae)...
  35. ncbi In vitro antioxidant and antiproliferative potential of medicinal plants used in traditional Indian medicine to treat cancer
    Arul Albert Baskar
    Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia
    Redox Rep 17:145-56. 2012
    ..Cynodon dactylon (L.) Pers, Costus speciosus (J. Koenig.) Smith Costaceae, Achyranthes aspera L., Amaranthus tristis Roxb...
  36. ncbi In vitro evaluation of calcium oxalate monohydrate crystals influenced by Costus igneus aqueous extract
    Manjula Kesavan
    Department of Biotechnology, Periyar Maniammai University, Thanjavur, Tamil Nadu, India
    Scand J Urol Nephrol 46:290-7. 2012
    ..Calcium oxalate monohydrate (COM) crystals are frequently found in urinary calculi (stones)...
  37. pmc Dehydrocostuslactone suppresses angiogenesis in vitro and in vivo through inhibition of Akt/GSK-3β and mTOR signaling pathways
    Chih Ya Wang
    Pharmacological Institute, College of Medicine, National Taiwan University, Taipei, Taiwan
    PLoS ONE 7:e31195. 2012
    The traditional Chinese medicine component dehydrocostuslactone (DHC) isolated from Saussurea costus (Falc.) Lipschitz, has been shown to have anti-cancer activity...
  38. ncbi The effects of wild ginger (Costus speciosus (Koen) Smith) rhizome extract and diosgenin on rat uterine contractions
    Wanwisa Lijuan
    Institute of Science, Suranaree University of Technology, Nakhon Ratchasima, Thailand
    Reprod Sci 18:516-24. 2011
    The aim of this study was to investigate the effects of wild ginger (Costus speciosus (Koen) Smith, Costaceae) rhizome extract on uterine contractility...
  39. ncbi [Studies on chemical constituents of two plants from Costus]
    Chun Feng Qiao
    Department of Pharmacognosy, China Pharmaceutical University, Nanjing 210038, Jiangsu, China
    Zhongguo Zhong Yao Za Zhi 27:123-5. 2002
    To study the chemical constituents of Costus speciosus and C. tonkinensis (Zingiberaceae) distributed in Yunnan province.
  40. ncbi In vitro antibacterial, phototoxic, and synergistic activity of ethanol extracts from Costus cf. arabicus L
    Francisco A B Cunha
    Laboratory of Microbiology and Molecular Biology, Regional University of Cariri, Crato, Ceará State, Brazil
    J Med Food 14:964-8. 2011
    In this study, ethanol extracts of stems and leaves of Costus cf. arabicus L. were evaluated for antibacterial activity against multidrug-resistant strains of Escherichia coli and Staphylococcus aureus...
  41. ncbi Changes in expression pattern of the teosinte branched1-like genes in the Zingiberales provide a mechanism for evolutionary shifts in symmetry across the order
    Madelaine E Bartlett
    Department of Plant and Microbial Biology, University of California Berkeley, 111 Koshland Hall, Berkeley, California 94720, USA
    Am J Bot 98:227-43. 2011
    ..In the Zingiberales, evolutionary shifts in symmetry have occurred in all floral whorls, making the order ideal for studying the evolution of this ecologically significant trait...
  42. ncbi Costunolide inhibits proinflammatory cytokines and iNOS in activated murine BV2 microglia
    Nirmala Arul Rayan
    Department of Biotechnology, Holy Cross College, Tiruchirapalli, India
    Front Biosci (Elite Ed) 3:1079-91. 2011
    Costunolide, a sesquiterpene lactone present in Costus speciosus root exerts a variety of pharmacological activity but its effects on neuroinflammation have not been studied...
  43. ncbi Antitrypanosomal sesquiterpene lactones from Saussurea costus
    Tasqiah Julianti
    Division of Pharmaceutical Biology, University of Basel, CH 4056 Basel, Switzerland
    Fitoterapia 82:955-9. 2011
    In the course of a larger screen of 1800 plant and fungal extracts, the ethyl acetate extract of Saussurea costus roots potently inhibited the growth of Trypanosoma brucei rhodesiense...
  44. ncbi The centromeric heterochromatin of Costus spiralis: poorly methylated and transiently acetylated during meiosis
    L Feitoza
    Laboratory of Plant Cytogenetics, Department of Botany, Federal University of Pernambuco, Recife, Brazil
    Cytogenet Genome Res 135:160-6. 2011
    The centromeric region of Costus spiralis is characteristically composed of a small heterochromatic DAPI(+) band flanked by a discrete decondensed region...
  45. ncbi Aqueous fraction from Costus spiralis (Jacq.) Roscoe leaf reduces contractility by impairing the calcium inward current in the mammalian myocardium
    Raquel Moreira Britto
    Laboratório de Biofísica do Coração, Departamento de Fisiologia, Universidade Federal de Sergipe, Aracaju, SE, Brazil
    J Ethnopharmacol 138:382-9. 2011
    Brazilian folk medicine uses infusion of Costus spiralis leaf to help people to treat arterial hypertension and syndromes of cardiac hyperexcitability.
  46. ncbi Antioxidant and antitopoisomerase activities in plant extracts of some Colombian flora from La Marcada Natural Regional Park
    Jaime Niño
    Grupo de Biotecnología Productos Naturales, Escuela de Tecnología Química, Universidad Tecnologica de Pereira, Pereira, Colombia
    Rev Biol Trop 59:1089-97. 2011
    ..In the DPPH assay, the n-hexane crude extract from Costus sp...
  47. pmc Assessment of anti-nociceptive efficacy of costus speciosus rhizome in swiss albino mice
    Sanjib Bhattacharya
    Bengal School of Technology A College of Pharmacy, Hooghly, West Bengal India
    J Adv Pharm Technol Res 1:34-40. 2010
    Present study attempts to evaluate the anti-nociceptive activity of the aqueous and ethanol extracts of Costus speciosus rhizome (CPA and CPE) in Swiss albino mice...
  48. ncbi Different types of plant chromatin associated with modified histones H3 and H4 and methylated DNA
    Lidiane Feitoza
    Laboratory of Plant Cytogenetics, Department of Botany, Federal University of Pernambuco, Recife, Brazil
    Genetica 139:305-14. 2011
    ..Both species, Costus spiralis and Eleutherine bulbosa, additionally have a small amount of classical heterochromatin detected by CMA/..
  49. pmc Traditional management of tuberculosis in Ogun State of Nigeria: the practice and ethnobotanical survey
    Omonike O Ogbole
    Department of Pharmacognosy, Faculty of Pharmacy, Olabisi Onabanjo University, Sagamu, Nigeria
    Afr J Tradit Complement Altern Med 7:79-84. 2010
    ..Cola acumminata (fruit), Garcinia kola (leaf), Vitallaria parodoxa (oil), Costus afer (stem), Pycnanthus angolensis (stem bark) and Aframomum melegueta (fruit) were the most frequently mentioned ..
  50. ncbi Surfactant-assisted pressurized liquid extraction for determination of flavonoids from Costus speciosus by micellar electrokinetic chromatography
    Yong Qin Chang
    Natural Sciences and Science Education Academic Group, Nanyang Technological University, Singapore
    J Sep Sci 34:462-8. 2011
    ..namely surfactant-assisted pressurized liquid extraction (PLE), was developed for the extraction of flavonoids in Costus speciosus flowers before MEKC analysis...
  51. ncbi Evaluation of phototoxic properties of fragrances
    Marianne Placzek
    Department of Dermatology and Allergology, Ludwig Maximilians University Munchen, Germany
    Acta Derm Venereol 87:312-6. 2007
    ..Moderate UVA-induced haemolysis (5-11%) was found with benzyl alcohol, bergamot oil, costus root oil, lime oil, orange oil, alpha-amyl cinnamic aldehyde and laurel leaf oil...
  52. ncbi Saussurea costus: botanical, chemical and pharmacological review of an ayurvedic medicinal plant
    Madan Mohan Pandey
    Pharmacognosy and Ethnopharmacology Division, National Botanical Research Institute, Rana Pratap Marg, Lucknow, India
    J Ethnopharmacol 110:379-90. 2007
    Saussurea costus (Falc.) Lipschitz, syn Saussurea lappa C.B. Clarke is a well known and important medicinal plant widely used in several indigenous systems of medicine for the treatment of various ailments, viz...
  53. pmc Phylogenetic origins of the Himalayan endemic Dolomiaea, Diplazoptilon and Xanthopappus (Asteraceae: Cardueae) based on three DNA regions
    Yu Jin Wang
    Key Laboratory of Qinghai Tibetan Plateau Ecological Adaptation, Northwest Plateau Institute of Biology, Chinese Academy of Sciences, Xining 810008, Qinghai, China
    Ann Bot 99:311-22. 2007
    ..In the present study, the phylogenetic relationships and origins of three such endemic genera were analysed, Dolomiaea, Diplazoptilon and Xanthopappus, all in the tribe Cardueae of Asteraceae...
  54. ncbi Reproductive isolation between two closely related hummingbird-pollinated neotropical gingers
    Kathleen M Kay
    Department of Plant Biology, Michigan State University, East Lansing 48824, USA
    Evolution 60:538-52. 2006
    ..I investigated the factors contributing to reproductive isolation between Costus pulverulentus and C. scaber (Costaceae), two closely related hummingbird-pollinated understory Neotropical herbs...
  55. ncbi Phyllosphere nitrogen relations: reciprocal transfer of nitrogen between epiphyllous liverworts and host plants in the understorey of a lowland tropical wet forest in Costa Rica
    Wolfgang Wanek
    Institute of Ecology and Conservation Biology, University of Vienna, Althanstrasse 14, A 1090 Vienna, Austria
    New Phytol 166:577-88. 2005
    ..interdependency, nitrogen fluxes between epiphyllous liverworts and their host leaves (Carludovica drudei, Costus laevis, Dieffenbachia concinna, Pentagonia wendlandii) were quantified by in situ15N-labelling techniques in a ..
  56. ncbi New steroidal saponins from rhizomes of Costus spiralis
    Bernadete P da Silva
    Laboratório de Química de Plantas Medicinais, Nucleo de Pesquisas de Produtos Naturais, Universidade Federal do Rio de Janeiro, PO Box 68045, CEP 21944 970 Rio de Janeiro, Brazil
    Z Naturforsch C 59:81-5. 2004
    Two new steroidal saponins were isolated from the rhizomes of Costus spiralis Rosc...
  57. ncbi Molecular cloning and functional expression of cDNAs encoding oxidosqualene cyclases from Costus speciosus
    Noriaki Kawano
    Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan
    Biol Pharm Bull 25:477-82. 2002
    b>Costus speciosus produces a large quantity of steroidal glycosides derived from the sole aglycone, diosgenin...
  58. pmc Medicinal and ethnoveterinary remedies of hunters in Trinidad
    C Lans
    Group Technology and Agrarian Development, Hollandseweg 1, 6706 KN Wageningen University, The Netherlands
    BMC Complement Altern Med 1:10. 2001
    ..Ethnomedicines are used by hunters for themselves and their hunting dogs in Trinidad. Plants are used for snakebites, scorpion stings, for injuries and mange of dogs and to facilitate hunting success...
  59. ncbi C-27 and C-3 glucosylation of diosgenin by cell suspension cultures of Costus speciosus
    G Indrayanto
    Laboratory of Pharmaceutical Biotechnology, Faculty of Pharmacy, Airlangga University, Surabaya, Indonesia
    J Asian Nat Prod Res 3:161-8. 2001
    ..27-O-beta-D-glucopyranosyl-(25R)-spirost-5-ene-3beta,27-diol was isolated from cell suspension cultures of Costus speciosus, following incubation with diosgenin, and its structure was elucidated using a combination of one- and ..
  60. ncbi Inhibition of inducible nitric oxide synthesis by the herbal preparation Padma 28 in macrophage cell line
    T Moeslinger
    Institute of Physiology, Vienna, Austria
    Can J Physiol Pharmacol 78:861-6. 2000
    ..Padma 28 decreased iNOS mRNA levels as shown by RT-PCR. Aqueous extracts from costi amari radix (costus root, the dried root of Saussurea lappa) and the outer cover of myrobalani fructus (the dried fruit of Terminalia ..
  61. ncbi Screening of Zingiberaceae extracts for antimicrobial and antioxidant activities
    M Habsah
    Department of Chemistry, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia
    J Ethnopharmacol 72:403-10. 2000
    Dichloromethane and methanol extracts of 13 Zingiberaceae species from the Alpinia, Costus and Zingiber genera were screened for antimicrobial and antioxidant activities...
  62. ncbi Molecular cloning and bacterial expression of a cDNA encoding furostanol glycoside 26-O-beta-glucosidase of Costus speciosus
    K Inoue
    Department of Pharmacognosy and Phytochemistry, Faculty of Pharmaceutical Sciences, The University of Tokyo, Japan
    FEBS Lett 389:273-7. 1996
    Furostanol glycoside 26-O-beta-glucosidase (F26G) purified from Costus speciosus rhizomes was digested with endoproteinase, and several internal peptide fragments were obtained...
  63. ncbi Nitrogen fixation by phyllosphere bacteria associated with higher plants and their colonizing epiphytes of a tropical lowland rainforest of Costa Rica
    Michael Fürnkranz
    Department of Chemical Ecology and Ecosystem Research, University of Vienna, Vienna, Austria
    ISME J 2:561-70. 2008
    ..N(2)-fixing bacterial communities of the plant species Carludovica drudei, Grias cauliflora and Costus laevis were investigated in more detail by analysis of the nifH gene and leaf-associated bacteria were identified ..
  64. ncbi The effects of subinhibitory concentrations of costus oil on virulence factor production in Staphylococcus aureus
    J Qiu
    Institute of Zoonoses, College of Animal Sciences and Veterinary Medicine, Jilin University, Changchun, China
    J Appl Microbiol 110:333-40. 2011
    To determine the antimicrobial activity of costus (Saussurea lappa) oil against Staphylococcus aureus, and to evaluate the influence of subinhibitory concentrations of costus oil on virulence-related exoprotein production in staph. aureus.
  65. pmc Effect of the insulin plant (Costus igneus) leaves on dexamethasone-induced hyperglycemia
    Akhila J Shetty
    Department of Pharmacology, Kasturba Medical College KMC, Mangalore Campus, Manipal University, Manipal, India
    Int J Ayurveda Res 1:100-2. 2010
    b>Costus igneus, commonly known as insulin plant in India, belongs to the family Costaceae...
  66. ncbi Antinociceptive and anti-inflammatory effects of Costus spicatus in experimental animals
    Lucindo J Quintans Júnior
    Departamento de Fisiologia, Universidade Federal de Sergipe DFS UFS, Sao Cristovao, Sergipe, Brazil
    Pharm Biol 48:1097-102. 2010
    b>Costus spicatus Swartz (Costaceae), commonly called "cana-do-brejo'" in Brazil's northeast, is a medicinal plant found in wet coastal forests. In folk medicine an infusion of the aerial parts is taken to treat inflammation and pain.
  67. ncbi Evidence for the involvement of Globosa-like gene duplications and expression divergence in the evolution of floral morphology in the Zingiberales
    Madelaine E Bartlett
    Department of Plant and Microbial Biology, University of California Berkeley, CA 94720, USA
    New Phytol 187:521-41. 2010
    ..Expression of two GLO homologs was assessed in Costus spicatus and Musa basjoo...
  68. ncbi Oxytocic effects of the aqueous leaf extract of Costus lucanusianus - family Costaceae on isolated non-pregnant rat uterus
    Omonkhelini J Owolabi
    Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Benin, Nigeria
    Pak J Pharm Sci 23:207-11. 2010
    b>Costus lucanusianus J. Braun (Costaceae) is a climbing herb, found mainly in the Niger Delta region of Nigeria. This plant is locally used in situations of pains, inflammation, dysmenorrhoea and in pyrexia...
  69. pmc Biochemical conservation and evolution of germacrene A oxidase in asteraceae
    Don Trinh Nguyen
    Department of Biological Sciences, University of Calgary, Calgary T2N 1N4, Canada
    J Biol Chem 285:16588-98. 2010
    ..further isolated from the representative species of three major subfamilies of Asteraceae (sunflower, chicory, and costus from Asteroideae, Cichorioideae, and Carduoideae, respectively) and also from the phylogenetically basal species, ..
  70. pmc The evolution of postpollination reproductive isolation in Costus
    Jenn M Yost
    Department of Ecology and Evolutionary Biology, University of California, Santa Cruz, CA 95064, USA
    Sex Plant Reprod 22:247-55. 2009
    ..We then review empirical studies in the plant genus Costus, evaluating documented postpollination barriers in light of these hypotheses...
  71. pmc Cytotoxic and antibacterial activities of endophytic fungi isolated from plants at the National Park, Pahang, Malaysia
    Nurul A M N Hazalin
    Universiti Teknologi MARA, Selangor Darul Ehsan, Malaysia
    BMC Complement Altern Med 9:46. 2009
    ..Endophytes, microorganisms which reside in plant tissues, have potential in producing novel metabolites for exploitation in medicine. Cytotoxic and antibacterial activities of a total of 300 endophytic fungi were investigated...
  72. ncbi Antihyperglycemic and insulin secretory activity of Costus pictus leaf extract in streptozotocin induced diabetic rats and in in vitro pancreatic islet culture
    G Gireesh
    Molecular Neurobiology and Cell Biology Unit, Centre for Neuroscience, Department of Biotechnology, Cochin University of Science and Technology, Cochin 682022, Kerala, India
    J Ethnopharmacol 123:470-4. 2009
    The leaves of Costus pictus D. Don were used extensively for its antihyperglycemic activity by the people in Kerala, India...
  73. pmc Costus spicatus tea failed to improve diabetic progression in C57BLKS/J db/db mice, a model of type 2 diabetes mellitus
    Amy C Keller
    Department of Biological Sciences, Lehman College and The Graduate Center, The City University of New York, Bronx, NY 10468, USA
    J Ethnopharmacol 121:248-54. 2009
    b>Costus spicatus Sw. (Costaceae) is a prominent medicinal herb used by Dominicans in the Dominican Republic and the United States for the treatment of diabetes, a growing epidemic in the Hispanic community...
  74. ncbi Modulation of sodium pumps by steroidal saponins
    Aloa Machado De Souza
    Instituto de Biofisica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Centro de Ciencias da Saude, Rio de Janeiro, Brazil
    Z Naturforsch C 59:432-6. 2004
    b>Costus spicatus, used in Brazilian traditional medicine to expel kidney stones, contains steroidal saponins with different chemical characteristics...
  75. ncbi Natural selection reinforces speciation in a radiation of neotropical rainforest plants
    Kathleen M Kay
    Department of Plant Biology, 166 Plant Biology Building, Michigan State University, East Lansing, Michigan 48824, USA
    Evolution 62:2628-42. 2008
    ..We used two approaches to test for reinforcement in a species radiation of Neotropical gingers in the genus Costus. First, we conducted an intensive study of Costus pulverulentus and Costus scaber, two recently diverged species ..
  76. ncbi A new sesquiterpene lactone from the roots of Saussurea lappa: structure-anticancer activity study
    A Robinson
    Natural Products Laboratory, Division of Organic Chemistry 1, Indian Institute of Chemical Technology, Hyderabad 500 607, India
    Bioorg Med Chem Lett 18:4015-7. 2008
    The dried roots of Saussurea lappa, called costus roots, are used in the traditional system of medicine for the treatment of cancer...
  77. ncbi Purification and characterization of furostanol glycoside 26-O-beta-glucosidase from Costus speciosus rhizomes
    K Inoue
    Department of Pharmacognosy and Phytochemistry, Faculty of Pharmaceutical Sciences, University of Tokyo, Japan
    FEBS Lett 378:157-60. 1996
    ..F26G) involved in this conversion was purified to apparent homogeneity for the first time from Costus speciosus rhizomes which accumulate these glycosides...