garcinia mangostana

Summary

Summary: A plant genus of the family CLUSIACEAE. It is the source of the mangosteen fruit.

Top Publications

  1. ncbi Antimycobacterial activity of prenylated xanthones from the fruits of Garcinia mangostana
    Sunit Suksamrarn
    Department of Chemistry, Faculty of Science, Srinakharinwirot University, Bangkok, Thailand
    Chem Pharm Bull (Tokyo) 51:857-9. 2003
  2. ncbi Xanthones and benzophenones from Garcinia griffithii and Garcinia mangostana
    Lien Hoa D Nilar Nguyen
    Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Republic of Singapore
    Phytochemistry 66:1718-23. 2005
  3. ncbi Antioxidant xanthones from the pericarp of Garcinia mangostana (Mangosteen)
    Hyun Ah Jung
    Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, USA
    J Agric Food Chem 54:2077-82. 2006
  4. doi Medicinal properties of mangosteen (Garcinia mangostana)
    José Pedraza-Chaverri
    Facultad de Quimica, Departamento de Biologia, Universidad Nacional Autonoma de Mexico, Ciudad Universitaria, 04510 Mexico, DF, Mexico
    Food Chem Toxicol 46:3227-39. 2008
  5. pmc α-Mangostin, a xanthone from mangosteen fruit, promotes cell cycle arrest in prostate cancer and decreases xenograft tumor growth
    Jeremy J Johnson
    Department of Pharmacy Practice, University of Illinois at Chicago College of Pharmacy, 833 South Wood Street, Chicago, IL 60612 7230, USA
    Carcinogenesis 33:413-9. 2012
  6. ncbi Effect of Garcinia mangostana on inflammation caused by Propionibacterium acnes
    Mullika Traidej Chomnawang
    Department of Microbiology, Faculty of Pharmacy, Mahidol University, Rachathevi, Bangkok, Thailand
    Fitoterapia 78:401-8. 2007
  7. ncbi Antifungal activity of alpha-mangostin against Candida albicans
    Ruchadaporn Kaomongkolgit
    Oral Diagnosis Department, Faculty of Dentistry, Naresuan University, Phitsanulok, Thailand
    J Oral Sci 51:401-6. 2009
  8. ncbi Antibacterial activity of alpha-mangostin against vancomycin resistant Enterococci (VRE) and synergism with antibiotics
    Y Sakagami
    Osaka Prefectural Institute of Public Health, Osaka, Japan
    Phytomedicine 12:203-8. 2005
  9. ncbi Cardioprotective effect of alpha-mangostin, a xanthone derivative from mangosteen on tissue defense system against isoproterenol-induced myocardial infarction in rats
    Pandima Devi Sampath
    Centre for Advanced Studies in Botany, University of Madras, Guindy Campus, Chennai, India
    J Biochem Mol Toxicol 21:336-9. 2007
  10. ncbi Anti-inflammatory activity of mangostins from Garcinia mangostana
    Lih Geeng Chen
    Graduate Institute of Biomedical and Biopharmaceutical Sciences, College of Life Sciences, National Chiayi University, 300 University Road, Chiayi 600, Taiwan, ROC
    Food Chem Toxicol 46:688-93. 2008

Research Grants

Scientific Experts

Detail Information

Publications107 found, 100 shown here

  1. ncbi Antimycobacterial activity of prenylated xanthones from the fruits of Garcinia mangostana
    Sunit Suksamrarn
    Department of Chemistry, Faculty of Science, Srinakharinwirot University, Bangkok, Thailand
    Chem Pharm Bull (Tokyo) 51:857-9. 2003
    Prenylated xanthones, isolated from the fruit hulls and the edible arils and seeds of Garcinia mangostana, were tested for their antituberculosis potential...
  2. ncbi Xanthones and benzophenones from Garcinia griffithii and Garcinia mangostana
    Lien Hoa D Nilar Nguyen
    Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Republic of Singapore
    Phytochemistry 66:1718-23. 2005
    ..The acetone extract of the heartwood of Garcinia mangostana contained one new diprenylated xanthone (mangoxanthone) and a new benzophenone (3',6-dihydroxy-2,4,4'-..
  3. ncbi Antioxidant xanthones from the pericarp of Garcinia mangostana (Mangosteen)
    Hyun Ah Jung
    Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, USA
    J Agric Food Chem 54:2077-82. 2006
    As part of ongoing research on cancer chemopreventive agents from botanical dietary supplements, Garcinia mangostana L. (commonly known as mangosteen) was selected for detailed study...
  4. doi Medicinal properties of mangosteen (Garcinia mangostana)
    José Pedraza-Chaverri
    Facultad de Quimica, Departamento de Biologia, Universidad Nacional Autonoma de Mexico, Ciudad Universitaria, 04510 Mexico, DF, Mexico
    Food Chem Toxicol 46:3227-39. 2008
    Many tropical plants have interesting biological activities with potential therapeutic applications. Garcinia mangostana Linn. (GML) belongs to the family of Guttiferae and is named "the queen of fruits"...
  5. pmc α-Mangostin, a xanthone from mangosteen fruit, promotes cell cycle arrest in prostate cancer and decreases xenograft tumor growth
    Jeremy J Johnson
    Department of Pharmacy Practice, University of Illinois at Chicago College of Pharmacy, 833 South Wood Street, Chicago, IL 60612 7230, USA
    Carcinogenesis 33:413-9. 2012
    ..01). The ability of α-mangostin to inhibit PCa in vitro and in vivo suggests α-mangostin may be a novel agent for the management of PCa...
  6. ncbi Effect of Garcinia mangostana on inflammation caused by Propionibacterium acnes
    Mullika Traidej Chomnawang
    Department of Microbiology, Faculty of Pharmacy, Mahidol University, Rachathevi, Bangkok, Thailand
    Fitoterapia 78:401-8. 2007
    ..Antioxidant activity was determined by DPPH scavenging and NBT reduction assay. The result showed that Garcinia mangostana possessed the most significant antioxidant activity and reduced reactive oxygen species production...
  7. ncbi Antifungal activity of alpha-mangostin against Candida albicans
    Ruchadaporn Kaomongkolgit
    Oral Diagnosis Department, Faculty of Dentistry, Naresuan University, Phitsanulok, Thailand
    J Oral Sci 51:401-6. 2009
    ..The strong antifungal activity and low toxicity of alpha-mangostin make it a promising agent for treatment of oral candidiasis...
  8. ncbi Antibacterial activity of alpha-mangostin against vancomycin resistant Enterococci (VRE) and synergism with antibiotics
    Y Sakagami
    Osaka Prefectural Institute of Public Health, Osaka, Japan
    Phytomedicine 12:203-8. 2005
    alpha-Mangostin, isolated from the stem bark of Garcinia mangostana L., was found to be active against vancomycin resistant Enterococci (VRE) and methicillin resistant Staphylococcus aureus (MRSA), with MIC values of 6.25 and 6.25 to 12...
  9. ncbi Cardioprotective effect of alpha-mangostin, a xanthone derivative from mangosteen on tissue defense system against isoproterenol-induced myocardial infarction in rats
    Pandima Devi Sampath
    Centre for Advanced Studies in Botany, University of Madras, Guindy Campus, Chennai, India
    J Biochem Mol Toxicol 21:336-9. 2007
    ..These findings indicate the protective effect of alpha-mangostin on lipid peroxidation and antioxidant tissue defense system during ISO-induced myocardial infarction in rats...
  10. ncbi Anti-inflammatory activity of mangostins from Garcinia mangostana
    Lih Geeng Chen
    Graduate Institute of Biomedical and Biopharmaceutical Sciences, College of Life Sciences, National Chiayi University, 300 University Road, Chiayi 600, Taiwan, ROC
    Food Chem Toxicol 46:688-93. 2008
    The fruit hull of Garcinia mangostana Linn (Guttiferae) is used as an anti-inflammatory drug in Southeast Asia. Two xanthones, alpha- and gamma-mangostins, were isolated from the fruit hull of G...
  11. ncbi Panaxanthone isolated from pericarp of Garcinia mangostana L. suppresses tumor growth and metastasis of a mouse model of mammary cancer
    Hitoshi Doi
    Department of Anatomy and Cell Biology, Osaka Medical College, Takatsuki, Osaka 569 8686, Japan
    Anticancer Res 29:2485-95. 2009
    ....
  12. doi Garcinia mangostana L.: a phytochemical and pharmacological review
    Dmitriy Obolskiy
    Center for Pharmacognosy and Phytotherapy, The School of Pharmacy University of London, 29 39 Brunswick Square, London WC1N 1AX, UK
    Phytother Res 23:1047-65. 2009
    b>Garcinia mangostana L. (mangosteen, Clusiaceae) has a long history of use as a medical plant, mostly in Southeast Asia. This is a review of the phytochemistry and pharmacology of mangosteen...
  13. ncbi Quantitative and qualitative determination of six xanthones in Garcinia mangostana L. by LC-PDA and LC-ESI-MS
    Xiuhong Ji
    National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS 38677, USA
    J Pharm Biomed Anal 43:1270-6. 2007
    ..The developed methods were applied to the determination of six xanthones in Garcinia mangostana products. The satisfactory results showed that the methods are effective for the analysis of real samples.
  14. doi Fatty acid synthase inhibitors of phenolic constituents isolated from Garcinia mangostana
    He Zhong Jiang
    State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China
    Bioorg Med Chem Lett 20:6045-7. 2010
    ..The bioassay-guided chemical investigation of the hulls of Garcinia mangostana led to the isolation of 13 phenolic compounds (1-13) mainly including xanthone and benzophenone, in which ..
  15. pmc Cytotoxic xanthone constituents of the stem bark of Garcinia mangostana (mangosteen)
    Ah Reum Han
    College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, USA
    J Nat Prod 72:2028-31. 2009
    Bioassay-guided fractionation of a chloroform-soluble extract of Garcinia mangostana stem bark, using the HT-29 human colon cancer cell line and an enzyme-based ELISA NF-kappaB assay, led to the isolation of a new xanthone, 11-hydroxy-3-..
  16. pmc Xanthones from the botanical dietary supplement mangosteen (Garcinia mangostana) with aromatase inhibitory activity
    Marcy J Balunas
    Department of Medicinal Chemistry and Pharmacognosy, Program for Collaborative Research in the Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Nat Prod 71:1161-6. 2008
    Twelve xanthone constituents of the botanical dietary supplement mangosteen (the pericarp of Garcinia mangostana) were screened using a noncellular, enzyme-based microsomal aromatase inhibition assay...
  17. doi Xanthone constituents of the fruits of Garcinia mangostana with anticomplement activity
    Gui Hua Quan
    Immune Modulators Research Center, Korea Research Institute of Bioscience and Biotechnology, 685 1 Ochangeup, Cheongwongun, Chungbuk 363 883, South Korea
    Phytother Res 24:1575-7. 2010
    Phytochemical investigation of a chloroform-soluble fraction of the freeze-dried fruits of Garcinia mangostana (Clusiaceace) with anticomplement activity in the classical pathway led to the identification of five known xanthones...
  18. ncbi Topical application of Garcinia mangostana L. pericarp gel as an adjunct to periodontal treatment
    Supanee Rassameemasmaung
    Department of Oral Medicine, Faculty of Dentistry, Mahidol University, Ratchathewi, Bangkok 10400, Thailand
    Complement Ther Med 16:262-7. 2008
    To evaluate the effects of gel containing Garcinia mangostana L. pericarp extract (GM gel) applied topically as an adjunct to periodontal treatment.
  19. doi Inhibitory effect of xanthones isolated from the pericarp of Garcinia mangostana L. on rat basophilic leukemia RBL-2H3 cell degranulation
    Tomohiro Itoh
    Gifu International Institute of Biotechnology, Bio active Substances Research, 1 1 Naka fudogaoka, Kakamigahara, Gifu 504 0838, Japan
    Bioorg Med Chem 16:4500-8. 2008
    Mangostin, Garcinia mangostana L. is used as a traditional medicine in southeast Asia for inflammatory and septic ailments...
  20. doi Effect of a mangosteen dietary supplement on human immune function: a randomized, double-blind, placebo-controlled trial
    Yu Ping Tang
    Department of Preventive Medicine, Yanjing Medical School, School of Public Health and Family Medicine, Capital Medical University, Beijing
    J Med Food 12:755-63. 2009
    ..001). The results indicated that the intake of an antioxidant-rich product significantly enhanced immune responses and improved the subject's self-appraisal on his or her overall health status...
  21. doi Ameliorative prospective of alpha-mangostin, a xanthone derivative from Garcinia mangostana against beta-adrenergic cathecolamine-induced myocardial toxicity and anomalous cardiac TNF-alpha and COX-2 expressions in rats
    Pandima Devi Sampath
    Centre for Advanced Studies in Botany, University of Madras, Guindy Campus, Chennai, India
    Exp Toxicol Pathol 60:357-64. 2008
    ..Restoration of cellular normalcy accredits the cytoprotective role of alpha-mangostin...
  22. doi Apoptotic effects of γ-mangostin from the fruit hull of Garcinia mangostana on human malignant glioma cells
    Hui Fang Chang
    Department of Pharmacognosy, School of Pharmacy, College of Pharmacy, and Center of e CAM, Taipei Medical University, 250 Wusing St, Taipei 110, Taiwan
    Molecules 15:8953-66. 2010
    ..effects of γ-mangostin, a xanthone derivative isolated and purified from the hull of the tropical fruit Garcinia mangostana. The γ-mangostin showed potent antiproliferative activity toward MGs in dose- and time-dependent manners...
  23. ncbi Antioxidative and neuroprotective activities of extracts from the fruit hull of mangosteen (Garcinia mangostana Linn.)
    Wanlop Weecharangsan
    Faculty of Pharmacy, Silpakorn University, Nakhonpathom, Thailand
    Med Princ Pract 15:281-7. 2006
    The aim of this study was to investigate the antioxidative and neuroprotective activities of various extracts from the fruit hull of mangosteen (Garcinia mangostana Linn., GM).
  24. doi Effects of compounds from Garcinia mangostana on inflammatory mediators in RAW264.7 macrophage cells
    Supinya Tewtrakul
    Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat Yai, Songkhla 90112, Thailand
    J Ethnopharmacol 121:379-82. 2009
    The fruit hull of Garcinia mangostana Linn. has been used in Thai traditional medicine for treatment of abscess and skin infection.
  25. pmc Doxorubicin-induced central nervous system toxicity and protection by xanthone derivative of Garcinia mangostana
    J Tangpong
    School of Allied Health Sciences and Public Health, Thasala, Nakhon Si Thammarat, Thailand
    Neuroscience 175:292-9. 2011
    ..The present study tested the protective effect of a xanthone derivative of Garcinia Mangostana against Dox-induced neuronal toxicity...
  26. ncbi Inhibition of cyclooxygenase and prostaglandin E2 synthesis by gamma-mangostin, a xanthone derivative in mangosteen, in C6 rat glioma cells
    Keigo Nakatani
    Department of Pharmaceutical Molecular Biology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba, Aramaki, Aoba ku, 980 8578, Sendai, Japan
    Biochem Pharmacol 63:73-9. 2002
    The fruit hull of mangosteen, Garcinia mangostana L., has been used for many years as a medicine for treatment of skin infection, wounds, and diarrhea in Southeast Asia...
  27. doi A MYB transcription factor regulates anthocyanin biosynthesis in mangosteen (Garcinia mangostana L.) fruit during ripening
    Yossapol Palapol
    Department of Horticulture, Faculty of Agriculture, Kasetsart University, Bangkok, 10900, Thailand
    Planta 229:1323-34. 2009
    Mangosteen (Garcinia mangostana L.) fruit undergo rapid red colour development, both on the tree and after harvest, resulting in high anthocyanin production in the pericarp...
  28. ncbi Inhibitions of histamine release and prostaglandin E2 synthesis by mangosteen, a Thai medicinal plant
    Keigo Nakatani
    Department of Pharmaceutical Molecular Biology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan
    Biol Pharm Bull 25:1137-41. 2002
    The fruit hull of mangosteen, Garcinia mangostana L. has been used as a Thai indigenous medicine for many years. However, its mechanism of action as a medicine has not been elucidated...
  29. ncbi Inhibitory effects of crude alpha-mangostin, a xanthone derivative, on two different categories of colon preneoplastic lesions induced by 1, 2-dimethylhydrazine in the rat
    Viengvansay Nabandith
    Tumor Pathology Division, Faculty of Medicine, University of the Ryukyus, Okinawa 903 0215, Japan
    Asian Pac J Cancer Prev 5:433-8. 2004
    ..study was to examine whether crude alpha-mangostin (a major xanthone derivative in mangosteen pericarp (Garcinia mangostana)) has short-term chemopreventive effects on putative preneoplastic lesions involved in rat colon ..
  30. ncbi Comparative study of health properties and nutritional value of durian, mangosteen, and snake fruit: experiments in vitro and in vivo
    Ratiporn Haruenkit
    Faculty of Agricultural Industry and Department of Soil Science, King Mongkut s Institute of Technology Ladkrabang, Ladkrabang, Bangkok 10520, Thailand
    J Agric Food Chem 55:5842-9. 2007
    ..were compared with snake fruit (Salacca edulis Reinw.) and mangosteen (Garcinia mangostana). Dietary fibers, minerals, and trace metals were comparable...
  31. ncbi What are the facts and myths about mangosteen?
    Wendy Marcason
    American Dietetic Association s Knowledge Center, Chicago, IL, USA
    J Am Diet Assoc 106:986. 2006
  32. doi Systematic analysis of in vitro photo-cytotoxic activity in extracts from terrestrial plants in Peninsula Malaysia for photodynamic therapy
    Cheng Yi Ong
    Cancer Research Initiatives Foundation CARIF, Subang Jaya Medical Centre, 1, Jalan SS12 1A, 47500 Subang Jaya, Selangor Darul Ehsan, Malaysia
    J Photochem Photobiol B 96:216-22. 2009
    ..Irvingiaceae), Knema curtisii (Myristicaceae), Dysoxylum sericeum (Meliaceae), Garcinia atroviridis, Garcinia mangostana and Calophyllum inophyllum (Clusiaceae), Ervatamia hirta (Apocynaceae), Cassia alata, Entada phaseoloides ..
  33. doi Berry fruits: compositional elements, biochemical activities, and the impact of their intake on human health, performance, and disease
    Navindra P Seeram
    Center for Human Nutrition, David Geffen School of Medicine, University of California, Los Angeles, California 90095, USA
    J Agric Food Chem 56:627-9. 2008
    ..the pomegranate ( Punica granatum), goji berries ( Lycium barbarum; also known as wolfberry), mangosteen ( Garcinia mangostana), the Brazilian açaí berry ( Euterpe oleraceae), and the Chilean maqui berry ( Aristotelia chilensis)...
  34. ncbi Field suppression of the invasive ant Wasmannia auropunctata (Hymenoptera: Formicidae) in a tropical fruit orchard in Hawaii
    Evann Souza
    Tropical Conservation Biology and Environmental Science Program, University of Hawaii at Hilo, Hilo, HI96720, USA
    J Econ Entomol 101:1068-74. 2008
    ..auropunctata in a rambutan, Nephelium lappaceum L. and mangosteen, Garcinia mangostana L., orchard by making treatments every 2 wk for 16 wk...
  35. doi Enhanced growth of lactobacilli in soymilk upon immobilization on agrowastes
    Sue Siang Teh
    School of Industrial Technology, Univ Sains Malaysia, 11800 Penang, Malaysia
    J Food Sci 75:M155-64. 2010
    ..the effects of agrowastes from durian (Durio zibethinus), cempedak (Artocarpus champeden), and mangosteen (Garcinia mangostana) as immobilizers for lactobacilli grown in soymilk...
  36. doi Xanthones with neuraminidase inhibitory activity from the seedcases of Garcinia mangostana
    Hyung Won Ryu
    Division of Applied Life Science BK21 program, EB NCRC, Institute of Agriculture and Life Science, Graduate School of Gyeongsang National University, Jinju 660 701, Republic of Korea
    Bioorg Med Chem 18:6258-64. 2010
    ..A series of xanthones 1-12 was isolated from the seedcases of Garcinia mangostana and evaluated for bacteria neuraminidase inhibitory activity...
  37. pmc Anti-cancer effects of xanthones from pericarps of mangosteen
    Yukihiro Akao
    Gifu International Institute of Biotechnology, 1 1 Naka fudogaoka, Kakamigahara, Gifu 504 0838, Japan Tel 81 583 71 4646
    Int J Mol Sci 9:355-70. 2008
    Mangosteen, Garcinia mangostana Linn, is a tree found in South East Asia, and its pericarps have been used as traditional medicine...
  38. ncbi Xanthones from Garcinia mangostana (Guttiferae)
    G C L Ee
    Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia
    Nat Prod Res 20:1067-73. 2006
    Studies on the stem of Garcinia mangostana have led to the isolation of one new xanthone mangosharin (1) (2,6-dihydroxy-8-methoxy-5-(3-methylbut-2-enyl)-xanthone) and six other prenylated xanthones, alpha-mangostin (2), beta-mangostin (3)..
  39. doi Activity of mangosteen xanthones and teleocidin a-2 in death receptor expression enhancement and tumor necrosis factor related apoptosis-inducing ligand assays
    Hiroyuki Kikuchi
    Graduate School of Pharmaceutical Sciences, Chiba University, Chiba 263 8522, Japan
    J Nat Prod 73:452-5. 2010
    ..5 (DR5) expression was carried out, and bioassay-guided fractionation of two organisms, the pericarp of Garcinia mangostana (mangosteen) and actinomycete CKK609 strain, led to the isolation of eight xanthone derivatives (1-8) and ..
  40. ncbi Xanthones from the green fruit hulls of Garcinia mangostana
    Sunit Suksamrarn
    Department of Chemistry, Faculty of Science, Srinakharinwirot University, Bangkok 10110, Thailand
    J Nat Prod 65:761-3. 2002
    ..mangostenol (1), mangostenone A (2), and mangostenone B (3), were isolated from the green fruit hulls of Garcinia mangostana, along with the known xanthones, trapezifolixanthone, tovophyllin B (4), alpha- and beta-mangostins, ..
  41. ncbi Antiproliferation, antioxidation and induction of apoptosis by Garcinia mangostana (mangosteen) on SKBR3 human breast cancer cell line
    Primchanien Moongkarndi
    Department of Microbiology, Faculty of Pharmacy, Mahidol University, Sri Ayudthaya Road, Rajdhevee, Bangkok 10400, Thailand
    J Ethnopharmacol 90:161-6. 2004
    ..apoptotic and antioxidative properties of crude methanolic extract (CME) from the pericarp of Garcinia mangostana (family Guttiferae) using human breast cancer (SKBR3) cell line as a model system...
  42. ncbi Two novel xanthones from Garcinia mangostana
    G Gopalakrishnan
    Centre for Natural Products SPIC Science Foundation 111, Mount Road, Chennai 600 032, India
    Fitoterapia 71:607-9. 2000
    The isolation of two novel xanthones isolated from the fruit hulls of Garcinia mangostana is reported. The structures were elucidated by means of spectroscopic analysis.
  43. ncbi Immunomodulatory activities of alpha-mangostin on peripheral blood mononuclear cells
    Pimolkan Kasemwattanaroj
    Department of Microbiology, Faculty of Pharmacy, Mahidol University, Bangkok 10400, Thailand
    Nat Prod Commun 8:1257-60. 2013
    Mangosteen (Garcinia mangostana L.) a tropical fruit, has been used in traditional medicine. A frequently used part of mangosteen is the pericarp, containing a high content of xanthones...
  44. ncbi Alpha-mangostin induces Ca2+-ATPase-dependent apoptosis via mitochondrial pathway in PC12 cells
    Ayumi Sato
    Department of Pharmaceutical Molecular Biology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan
    J Pharmacol Sci 95:33-40. 2004
    ..Among these compounds, alpha-mangostin, from the fruit hull of Garcinia mangostana L., had the most potent effect with the EC(50) value of 4 microM...
  45. ncbi gamma-Mangostin inhibits inhibitor-kappaB kinase activity and decreases lipopolysaccharide-induced cyclooxygenase-2 gene expression in C6 rat glioma cells
    Keigo Nakatani
    Department of Pharmaceutical Molecular Biology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba, Aramaki, Aoba ku, Sendai 980 8578, Japan
    Mol Pharmacol 66:667-74. 2004
    We investigated the effect of gamma-mangostin purified from the fruit hull of the medicinal plant Garcinia mangostana on spontaneous prostaglandin E(2) (PGE(2)) genase release and inducible cyclooxy-2 (COX-2) gene expression in C6 rat ..
  46. ncbi Biological activity and stability of mangosteen as a potential natural color
    Nattaya Lourith
    School of Cosmetic Science, Mae Fah Luang University, Chiang Rai, Thailand
    Biosci Biotechnol Biochem 75:2257-9. 2011
    ..0 mg/mL at pH 3 at 23 °C over 7 d. Mangosteen pericarp extracts can therefore be used in pharmaceutical products that require low to medium pH...
  47. pmc Xanthones in mangosteen juice are absorbed and partially conjugated by healthy adults
    Chureeporn Chitchumroonchokchai
    Department of Human Nutrition, The Ohio State University, Columbus, OH, USA
    J Nutr 142:675-80. 2012
    ..These results show that xanthones in mangosteen juice are absorbed when ingested along with a high-fat meal, although release of xanthones from pericarp particles during digestion may be limited...
  48. pmc Alterations in cell cycle and induction of apoptotic cell death in breast cancer cells treated with α-mangostin extracted from mangosteen pericarp
    Hitomi Kurose
    Division of Life Sciences, Department of Anatomy and Cell Biology, Osaka Medical College, Takatsuki, Osaka, Japan
    J Biomed Biotechnol 2012:672428. 2012
    ..In conclusion, α-mangostin may be useful as a therapeutic agent for breast cancer carrying a p53 mutation and having HER2- and hormone receptor-negative subtypes...
  49. ncbi Antibacterial activity of extracts from five medicinal plants and their formula against bacteria that cause chronic wound infection
    Pornthep Temrangsee
    Faculty of Medicine, Thammasat University, Pathumthani, Thailand
    J Med Assoc Thai 94:S166-71. 2011
    ..Antibacterial activity of several herbal plants has been reported. Thai medicinal plants which possess biological activities are potential to develop an alternative treatment of bacterial infection...
  50. doi In vivo toxicity and antitumor activity of mangosteen extract
    Nuttavut Kosem
    Innovation Center for Medical Redox Navigation, Kyushu University, Fukuoka, 812 8582, Japan
    J Nat Med 67:255-63. 2013
    Mangosteen (Garcinia mangostana) has been widely used in the traditional medicine of Thailand to treat various ailments, especially diseases of the digestive system and infections...
  51. doi Anti-skin cancer properties of phenolic-rich extract from the pericarp of mangosteen (Garcinia mangostana Linn.)
    Jing J Wang
    Level 4, Health Science Building, Department of Medical Biotechnology, Flinders Medical Sciences and Technology, School of Medicine, Faculty of Health Science, Flinders University, Registry Road, Bedford Park, Adelaide 5042, Australia
    Food Chem Toxicol 50:3004-13. 2012
    ..Apoptosis was significantly increased after MPEE treatment of SK-MEL-28 cells. Hence, MPEE showed strong anti-skin cancer effect on these two skin cancer cell lines, with potential as an anti-skin cancer agent...
  52. doi Gamma-mangostin, a micronutrient of mangosteen fruit, induces apoptosis in human colon cancer cells
    Hui Fang Chang
    Department of Pharmacognosy, School of Pharmacy, College of Pharmacy, and Center of e CAM, Taipei Medical University, 250 Wusing St, Taipei 110, Taiwan
    Molecules 17:8010-21. 2012
    ..The treatment of colorectal cancer includes surgery, radiation therapy and chemotherapy. Mangosteen (Garcinia mangostana) is a famous Asian tropical fruit. γ-Mangostin is a xanthone derivative isolated from the fruit hull...
  53. pmc In vitro and in vivo anti-colon cancer effects of Garcinia mangostana xanthones extract
    Abdalrahim F A Aisha
    Department of Pharmacology, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden, 11800, Pulau Penang, Malaysia
    BMC Complement Altern Med 12:104. 2012
    ..Xanthones are a group of oxygen-containing heterocyclic compounds with remarkable pharmacological effects such as anti-cancer, antioxidant, anti-inflammatory, and antimicrobial activities...
  54. ncbi [Optimize technique of extracting alpha-mangostin from pericarp of Garcinia mangostana by supersonic wave using central composite design-response surface methodology]
    Yan Zhao
    College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China
    Zhong Yao Cai 35:973-7. 2012
    To optimize the extraction technique for alpha-mangostin from pericarp of Garcinia Mangostana.
  55. doi Chemical genetic screen in fission yeast reveals roles for vacuolar acidification, mitochondrial fission, and cellular GMP levels in lifespan extension
    Jessica Stephan
    Zentrum für Medizinische Biotechnologie, Universitat Duisburg Essen, Essen, Germany
    Aging Cell 12:574-83. 2013
    ..Taken together, these results reveal unanticipated anti-aging activities for several phytochemicals and open up opportunities for the development of novel anti-aging therapies...
  56. doi Pharmacokinetic properties of pure xanthones in comparison to a mangosteen fruit extract in rats
    Li Li
    Department of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, FL, USA
    Planta Med 79:646-53. 2013
    The xanthones α-mangostin and γ-mangostin are the major bioactive compounds in Garcinia mangostana (mangosteen) fruit extracts. Previously, we reported the pharmacokinetic properties of α-mangostin in rats...
  57. doi Phytochemical, antimicrobial and antiprotozoal evaluation of Garcinia mangostana pericarp and α-mangostin, its major xanthone derivative
    Shaza M Al-Massarani
    Department of Pharmacognosy, College of Pharmacy, King Saud University, P O Box 2457, Riyadh 11451, Saudi Arabia
    Molecules 18:10599-608. 2013
    Five xanthone derivatives and one flavanol were isolated from the dichloromethane extract of Garcinia mangostana. Dichloromethane, ethyl acetate extract and the major xanthone (α-mangostin) were evaluated in vitro against erythrocytic ..
  58. doi Antitumour and free radical scavenging effects of γ-mangostin isolated from Garcinia mangostana pericarps against hepatocellular carcinoma cell
    Hui Fang Chang
    Department of Pharmacognosy, School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, Taiwan
    J Pharm Pharmacol 65:1419-28. 2013
    ..In this study, we wanted to select and develop some of novel effectual agents or phytochemicals of γ-mangostin for clinical management or prevent hepatocellular carcinoma cell (HCC)...
  59. ncbi Effect of mangosteen (Garcinia mangostana L.) extracts as a feed additive on growth and hematological parameters of African catfish (Clarias gariepinus) fingerlings
    C Soosean
    Department of Biotechnology, Faculty of Applied Sciences, AIMST University Batu 31 2 Bukit Air Nasi, Jalan Bedong Semeling, Bedong, Kedah Darul Aman, Malaysia
    Eur Rev Med Pharmacol Sci 14:605-11. 2010
    The efficacy of dietary inclusion of various parts of mangosteen (Garcinia mangostana L.) extract on growth and hematological parameters of African catfish (Clarias gariepinus) fingerlings were investigated.
  60. doi Antioxidant, free radical-scavenging activity and cytotoxicity of different solvent extracts and their phenolic constituents from the fruit hull of mangosteen (Garcinia mangostana)
    Tanasait Ngawhirunpat
    Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, Thailand
    Pharm Biol 48:55-62. 2010
    ..and cytotoxicity of three extracts (water, methanol, and hexane) from the fruit hull of mangosteen (Garcinia mangostana Linn...
  61. doi Removal of Pb(II), Cd(II) and Co(II) from aqueous solution using Garcinia mangostana L. fruit shell
    R Zein
    Faculty of Mathematics and Natural Sciences, Andalas University, Padang, Indonesia
    J Hazard Mater 181:52-6. 2010
    ..0 for cobalt. The metal removal rates were rapid, with 90% of the total adsorption taking place within 60 min. Mangosteen shell showed the highest potential for the removal of toxic metals in aqueous solution...
  62. doi Use of asiatic pennywort Centella asiatica aqueous extract as a bath treatment to control columnaris in Nile tilapia
    P Rattanachaikunsopon
    Department of Biological Science, Faculty of Science, Ubon Ratchathani University, Warin Chamrap, Ubon Ratchathani 34190, Thailand
    J Aquat Anim Health 22:14-20. 2010
    ..kalmegh Andrographis paniculata, candle bush Cassia alata, Asiatic pennywort Centella asiatica, mangosteen Garcinia mangostana, pomegranate Punica granatum, and guava Psidium guajava), the aqueous extract of Asiatic pennywort ..
  63. ncbi Antiproliferative activity of Thai medicinal plant extracts on human breast adenocarcinoma cell line
    Primchanien Moongkarndi
    Department of Microbiology, Faculty of Pharmacy, Mahidol University, Rajdhevee, Sri Ayudthaya Rd, Bangkok 10400, Thailand
    Fitoterapia 75:375-7. 2004
    ..b>Garcinia mangostana showed the most potent activity...
  64. ncbi Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines
    Kenji Matsumoto
    Gifu International Institute of Biotechnology, 1 1 Naka fudogaoka, Kakamigahara, Gifu 504 0838, Japan
    J Nat Prod 66:1124-7. 2003
    We examined the effects of six xanthones from the pericarps of mangosteen, Garcinia mangostana, on the cell growth inhibition of human leukemia cell line HL60. All xanthones displayed growth inhibitory effects...
  65. doi A new antioxidant xanthone from the pericarp of Garcinia mangostana Linn
    Yan Zhao
    College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China
    Nat Prod Res 24:1664-70. 2010
    The air-dried fruit hulls of Garcinia mangostana Linn. were extracted with 85% ethanol...
  66. ncbi Xanthones from the heartwood of Garcinia mangostana
    - Nilar
    Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore
    Phytochemistry 60:541-8. 2002
    Twelve xanthones were isolated from the hexane extract of the heartwood of Garcinia mangostana from Myanmar. Their structures were determined using 1D and 2D NMR techniques
  67. ncbi Sigmoid colon perforation by ingested Sandorica seed
    P Somboonpanya
    Department of Surgery, Prachomklao Hospital, Phetchaburi, Thailand
    J Med Assoc Thai 84:1751-3. 2001
    ..Post-operative complications included two cases of wound infection...
  68. ncbi Inhibition of chemiluminescence and chemotactic activity of phagocytes in vitro by the extracts of selected medicinal plants
    Ibrahim Jantan
    J Nat Med 65:400-5. 2011
    ..xanthorrhiza and Garcinia mangostana L. Among the extracts studied, C. mangga Valton & Vazsjip, Piper nigrum L. and Labisia pumila var...
  69. doi Pharmacokinetics of α-mangostin in rats after intravenous and oral application
    Li Li
    Department of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA
    Mol Nutr Food Res 55:S67-74. 2011
    The xanthone α-mangostin is one of the major bioactive secondary metabolites in Garcinia mangostana. Until now, in vivo studies on the absorption, bioavailability, disposition, and metabolism of α-mangostin are limited.
  70. doi γ-Mangostin increases serotonin 2A/2C, muscarinic, histamine and bradykinin receptor mRNA expression
    Monrudee Sukma
    Department of Pharmacology and Toxicology, Faculty of Pharmacy, Silpakorn University, Muang, Nakhon Pathom 73000, Thailand
    J Ethnopharmacol 135:450-4. 2011
    Mangostin is a xanthone found in the fruit hulls of Garcinia mangostana L., which have long been used in Southeast Asia as a traditional medicine for the treatment of abdominal pain, dysentery, wound infections, fever and convulsions...
  71. doi Two new xanthones from the pericarp of Garcinia mangostana
    Yan Zhao
    College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, China
    Nat Prod Res 26:61-5. 2012
    ..2), were isolated from the pericarp of Garcinia mangostana. Their structures were elucidated by spectral means (1-D and 2-D NMR, MS).
  72. doi Protective effect of α-mangostin on cardiac reperfusion damage by attenuation of oxidative stress
    Mabel Buelna-Chontal
    Department of Biology, Faculty of Chemistry, National Autonomous University of Mexico, Mexico City, Mexico
    J Med Food 14:1370-4. 2011
    This study was designed to investigate if α-mangostin (α-M), a xanthone present in the pericarp of Garcinia mangostana L., was able to protect against reperfusion injury in Langendorff-reperfused hearts...
  73. doi Alpha-mangostin suppresses PC-3 human prostate carcinoma cell metastasis by inhibiting matrix metalloproteinase-2/9 and urokinase-plasminogen expression through the JNK signaling pathway
    Shun Hsing Hung
    Division of Urology, Department of Surgery, Chi Mei Medical Center, No 901, Jhong Hua Road, Yong Kang, Tainan 710, Taiwan, Republic of China
    J Agric Food Chem 57:1291-8. 2009
    Alpha-mangostin, a component of Garcinia mangostana Linn, is a xanthone derivative shown to have antioxidant and anticarcinogen properties...
  74. ncbi Molecular diversity of fungal endophytes isolated from Garcinia mangostana and Garcinia parvifolia
    Jiun Horng Sim
    Department of Biomedical Science, Faculty of Medicine and Health Sciences, University Putra Malaysia, Serdang, Selangor Darul Ehsan, Malaysia
    J Microbiol Biotechnol 20:651-8. 2010
    ..Glomerella sp., Guignardia sp., and Phomopsis sp. appeared to be the predominant endophytic fungi group in Garcinia mangostana and Garcinia parvifolia...
  75. doi Assessment of antioxidant capacity and cytotoxicity of selected Malaysian plants
    Lai Teng Ling
    Department of Physiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    Molecules 15:2139-51. 2010
    Thirteen Malaysian plants; Artocarpus champeden, Azadirachta indica, Fragaria x ananassa, Garcinia mangostana, Lawsonia inermis, Mangifera indica, Nephelium lappaceum, Nephelium mutobile, Peltophorum pterocarpum, Psidium guajava and ..
  76. doi Protective effect of mangosteen extract against beta-amyloid-induced cytotoxicity, oxidative stress and altered proteome in SK-N-SH cells
    Primchanien Moongkarndi
    Department of Microbiology, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand
    J Proteome Res 9:2076-86. 2010
    ..b>Garcinia mangostana L. (mangosteen) has been recognized as a major source of natural antioxidants that could decrease ROS...
  77. ncbi Characterized mechanism of alpha-mangostin-induced cell death: caspase-independent apoptosis with release of endonuclease-G from mitochondria and increased miR-143 expression in human colorectal cancer DLD-1 cells
    Yoshihito Nakagawa
    Gifu International Institute of Biotechnology, 1 1 Naka fudogaoka, Kakamigahara, Gifu 504 0838, Japan
    Bioorg Med Chem 15:5620-8. 2007
    alpha-Mangostin, a xanthone from the pericarps of mangosteen (Garcinia mangostana Linn.), was evaluated for in vitro cytotoxicity against human colon cancer DLD-1 cells...
  78. ncbi Validation of LC for the determination of alpha-mangostin in mangosteen peel extract: a tool for quality assessment of Garcinia mangostana L
    Sukit Yodhnu
    Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand
    J Chromatogr Sci 47:185-9. 2009
    Mangosteen, Garcinia mangostana L., is known as the "Queen of fruits" and can be cultivated in the tropical rainforest such as Malaysia, Indonesia, and Thailand...
  79. ncbi HPLC analysis of selected xanthones in mangosteen fruit
    Edward B Walker
    Department of Chemistry, Weber State University, Ogden, Utah 84403 2503, USA
    J Sep Sci 30:1229-34. 2007
    ..This analytical method is applied to the analysis of these xanthones in the rind of the mangosteen fruit, Garcinia mangostana.
  80. ncbi Oligomeric proanthocyanidins from mangosteen pericarps
    Caili Fu
    Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Republic of Singapore
    J Agric Food Chem 55:7689-94. 2007
    ..The isolated proanthocyanidins are potent peroxyl radical scavengers as evidenced by the high oxygen radical scavenging capacity at 1.7 x 10 (4) micromol TE/g, much higher than that of pine bark and grape seed extracts...
  81. ncbi Assay-guided fractionation study of alpha-amylase inhibitors from Garcinia mangostana pericarp
    Alvin Eng Kiat Loo
    Department of Chemistry, National University of Singapore, Republic of Singapore
    J Agric Food Chem 55:9805-10. 2007
    Alpha-amylase inhibitor (alpha-AI) activity of Garcinia mangostana, commonly known as mangosteen, pericarp extracts was studied by assay guided fractionations from lipophilic to hydrophilic using combined solvent extraction and Amberlite ..
  82. doi Centrifugal partition chromatography directly interfaced with mass spectrometry for the fast screening and fractionation of major xanthones in Garcina mangostana
    E Destandau
    ICOA, Universite d Orleans, UMR CNRS 6005, 45067 Orleans Cedex 2, France
    J Chromatogr A 1216:1390-4. 2009
    ..The dual mode or elution-extrusion which are less solvent-consuming and faster than the elution mode were used without loss of ionisation and detection...
  83. doi Antibacterial activity of Thai medicinal plants against methicillin-resistant Staphylococcus aureus
    Mullika Traidej Chomnawang
    Department of Microbiology, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand
    Fitoterapia 80:102-4. 2009
    ..Seventeen Thai medicinal plants were investigated for their activity against MRSA. Garcinia mangostana was identified as the most potent plant, and its activity was traced to the prenylated xanthone, alpha-..
  84. doi Pichia garciniae sp. nov., isolated from a rotten mangosteen fruit (Garcinia mangostana L., Clusiaceae)
    Bhaskar Bhadra
    Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 500007, India
    Int J Syst Evol Microbiol 58:2665-9. 2008
    Ascogenous yeasts were isolated from a decaying mangosteen fruit (Garcinia mangostana L., Clusiaceae). Based on colony morphology and RAPD analysis, the strains were grouped into four groups (G-I, G-II, G-III and G-IV)...
  85. ncbi Thin-layer chromatography-densitometric analysis of alpha-mangostin content in Garcinia mangostana fruit rind extracts
    Werayut Pothitirat
    Mahidol University, Department of Pharmacognosy, Faculty of Pharmacy, 447 Sri Ayudhaya Rd, Ratchatewi, Bangkok, Thailand
    J AOAC Int 91:1145-8. 2008
    The fruit rinds of mangosteen (Garcinia mangostana Linn.) have long been used as traditional medicines for treatment of skin infections, wounds, and diarrhea...
  86. ncbi Evaluating the efficacy in improving facial photodamage with a mixture of topical antioxidants
    Jessica Hsu
    University of California, San Diego, USA
    J Drugs Dermatol 6:1141-8. 2007
    ..9 mm3. The addition of 3 antioxidants, green and white teas, mangosteen, and pomegranate, have an additive effect to enhance the improvement of age-related changes in the skin...
  87. ncbi Effects of alpha-mangostin from mangosteen pericarp extract and imidacloprid on Nilaparvata lugens (Stal.) and non-target organisms: toxicity and detoxification mechanism
    Vasakorn Bullangpoti
    Dept of Zoology, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand
    Commun Agric Appl Biol Sci 72:431-41. 2007
    ....
  88. ncbi Electrospun poly(vinyl alcohol) fiber mats as carriers for extracts from the fruit hull of mangosteen
    Praneet Opanasopit
    Faculty of Pharmacy, Silpakorn University, Thailand
    J Cosmet Sci 59:233-42. 2008
    ..5%, 5%, and 10% w/w of the extract at 120 min were 73.2%, 83.6%, and 81.3% w/w, respectively. However, much slower release from the cast films was observed (i.e., 4.3%, 29.1%, and 40.8% w/w, respectively)...
  89. ncbi Effects of herbal mouthwash containing the pericarp extract of Garcinia mangostana L on halitosis, plaque and papillary bleeding index
    Supanee Rassameemasmaung
    Department of Oral Medicine, Faculty of Dentistry, Mahidol University, Bangkok, Thailand
    J Int Acad Periodontol 9:19-25. 2007
    ....
  90. doi Comparison of bioactive compounds content, free radical scavenging and anti-acne inducing bacteria activities of extracts from the mangosteen fruit rind at two stages of maturity
    Werayut Pothitirat
    Department of Pharmacognosy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand
    Fitoterapia 80:442-7. 2009
    ..Thus, the young and mature stages of mangosteen fruit rind should be beneficial for further development of antioxidant and anti-acne pharmaceutical preparations, respectively...
  91. ncbi Mangosteen for the cancer patient: facts and myths
    Simon Yeung
    Memorial Sloan Kettering Cancer Center, New York, NY, USA
    J Soc Integr Oncol 4:130-4. 2006
    ..Cancer patients should use caution before consuming mangosteen products as they can potentially interact with cancer treatments and also affect blood sugar levels...
  92. pmc Evaluation of Mangosteen juice blend on biomarkers of inflammation in obese subjects: a pilot, dose finding study
    Jay K Udani
    Medicus Research LLC, Northridge, CA 91325, USA
    Nutr J 8:48. 2009
    ..The purpose of this study was to evaluate the effect of multiple dosages of a proprietary Mangosteen Juice blend on indicators of inflammation and antioxidant levels in obese patients with elevated C-reactive protein (CRP) levels...
  93. doi Bioavailability and antioxidant effects of a xanthone-rich Mangosteen (Garcinia mangostana) product in humans
    Miwako Kondo
    Brunswick Laboratories, Norton, Massachusetts 02766, USA
    J Agric Food Chem 57:8788-92. 2009
    ..Overall, this study demonstrated the bioavailability of antioxidants from a xanthone-rich mangosteen product and its in vivo antioxidant effects...
  94. doi Mitigation of mitochondrial dysfunction and regulation of eNOS expression during experimental myocardial necrosis by alpha-mangostin, a xanthonic derivative from Garcinia mangostana
    Pandima Devi Sampath
    Center for Advanced Studies in Botany, University of Madras, Chennai, India
    Drug Chem Toxicol 32:344-52. 2009
    ....
  95. doi Two new prenylated xanthones and a new prenylated tetrahydroxanthone from the pericarp of Garcinia mangostana
    Yaozheng Zhang
    Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, PR China
    Fitoterapia 81:595-9. 2010
    ..garcimangosxanthone A-C (1-3), along with fourteen known xanthones were isolated from the pericarp of Garcinia mangostana. Their structures were elucidated on the basis of spectroscopic data...
  96. ncbi A geranylated biphenyl derivative from Garcinia malvgostana
    H R W Dharmaratne
    Natural Products Programme, Institute of Fundamental Studies, Kandy 20000, Sri Lanka
    Nat Prod Res 19:239-43. 2005
    Extracts of root bark, stem bark and the latex collected from the green fruits of Garcinia mangostana gave alpha-mangostin, beta-mangostin, gamma-mangostin, garcinone-E, methoxy-beta-mangostin and a new geranylated biphenyl derivative 3-..
  97. doi New medicinal properties of mangostins: analgesic activity and pharmacological characterization of active ingredients from the fruit hull of Garcinia mangostana L
    Jihong Cui
    Department of Biological Science and Technology, School of Life Sciences, Sun Yat Sen University, Guangzhou, Guangdong Province 510275, People s Republic of China
    Pharmacol Biochem Behav 95:166-72. 2010
    The fruit hull of Garcinia mangostana L...
  98. doi Xanthones from mangosteen inhibit inflammation in human macrophages and in human adipocytes exposed to macrophage-conditioned media
    Akkarach Bumrungpert
    Department of Nutrition, Faculty of Public Health, Mahidol University, Bangkok, Thailand
    J Nutr 140:842-7. 2010
    ....
  99. ncbi Antimicrobial effects of Thai medicinal plants against acne-inducing bacteria
    Mullika Traidej Chomnawang
    Department of Microbiology, Faculty of Pharmacy, Mahidol University, 447 Sri Ayudthaya Road, Rachathevi, Bangkok 10400, Thailand
    J Ethnopharmacol 101:330-3. 2005
    ..Among those, Senna alata, Eupatorium odoratum, Garcinia mangostana, and Barleria lupulina had strong inhibitory effects...
  100. ncbi Cytotoxic prenylated xanthones from the young fruit of Garcinia mangostana
    Sunit Suksamrarn
    Department of Chemistry, Faculty of Science, Srinakharinwirot University, Sukhumvit, Bangkok, Thailand
    Chem Pharm Bull (Tokyo) 54:301-5. 2006
    ..E (3), together with 16 known xanthones 4-19, were isolated from the young fruit (7-week maturity stage) of Garcinia mangostana. The structural elucidation of the new compounds was mainly established on the basis of 1D and 2D NMR and ..
  101. ncbi Prenylated xanthones as potential antiplasmodial substances
    Wilawan Mahabusarakam
    Department of Chemistry, Prince of Songkla University, Hat Yai, Songkhla, Thailand
    Planta Med 72:912-6. 2006
    Mangostin, the major xanthone of Garcinia mangostana, and a series of synthetic derivatives were investigated for their in vitro antiplasmodial activity against Plasmodium falciparum...

Research Grants10

  1. Magnesium and Asthma - Clinical Trials
    Judith Stern; Fiscal Year: 2004
    ..We do not anticipate that Mg supplementation will replace conventional treatment, but may complement and decrease the need for conventional medications. ..
  2. OBESE FEMALE RESTRAINED EATERS : TWO TREATMENT OPTIONS
    Judith Stern; Fiscal Year: 2002
    ..A manual of procedures will be generated to assist others in replicating the intervention. ..
  3. Discovery of Anticancer Agents of Diverse Natural Orgin
    ALAN KINGHORN; Fiscal Year: 2007
    ....