ruta

Summary

Summary: A plant genus of the family RUTACEAE. Members contain quinoline alkaloids.

Top Publications

  1. ncbi Effect of Ruta graveolens L. and Euphorbia peplus L. anti-inflammatory extracts on nutritional status of rats and the safety of their use
    Sahar Y Al-Okbi
    Food Sciences and Nutrition Department, National Research Centre, Dokki, Cairo, Egypt
    Indian J Exp Biol 40:45-8. 2002
  2. ncbi Anti-tumour activity of Ruta graveolens extract
    K C Preethi
    Amala Cancer Research Centre, Amala Nagar, Thrissur, Kerala 680555, India
    Asian Pac J Cancer Prev 7:439-43. 2006
  3. ncbi Inhibition of lipopolysaccharide-inducible nitric oxide synthase and IL-1beta through suppression of NF-kappaB activation by 3-(1'-1'-dimethyl-allyl)-6-hydroxy-7-methoxy-coumarin isolated from Ruta graveolens L
    Sunil Kumar Raghav
    Proteomics and Structural Biology Division, Institute of Genomics and Integrative Biology, Delhi University Campus, Mall Road, Delhi 110 007, India
    Eur J Pharmacol 560:69-80. 2007
  4. ncbi Anti-inflammatory effect of Ruta graveolens L. in murine macrophage cells
    S K Raghav
    Institute of Genomics and Integrative Biology, Delhi University Campus, Mall Road, Delhi 110007, India
    J Ethnopharmacol 104:234-9. 2006
  5. pmc Ethnomedicines used in Trinidad and Tobago for reproductive problems
    Cheryl Lans
    BCICS, University of Victoria, British Columbia, V8W 2Y2, Canada
    J Ethnobiol Ethnomed 3:13. 2007
  6. doi Unusually divergent 4-coumarate:CoA-ligases from Ruta graveolens L
    Alexander Endler
    Institut fur Pharmazeutische Biologie, Philipps Universitat Marburg, Marburg, Germany
    Plant Mol Biol 67:335-46. 2008
  7. ncbi Algicidal and antifungal compounds from the roots of Ruta graveolens and synthesis of their analogs
    Kumudini M Meepagala
    USDA ARS, Natural Products Utilization Research Unit, P O Box 8048, University, MS 38677, USA
    Phytochemistry 66:2689-95. 2005
  8. ncbi Specific accumulation and revised structures of acridone alkaloid glucosides in the tips of transformed roots of Ruta graveolens
    Inna Kuzovkina
    Timiryazev Institute of Plant Physiology, Russian Academy of Sciences, Botanicheskaya ul 35, 127276 Moscow, Russia
    Phytochemistry 65:1095-100. 2004
  9. ncbi Investigation of cytotoxic activity on human cancer cell lines of arborinine and furanoacridones isolated from Ruta graveolens
    Borbála Réthy
    Department of Pharmacodynamics and Biopharmacy, University of Szeged, Szeged, Hungary
    Planta Med 73:41-8. 2007
  10. ncbi Free phenolic acids in Ruta graveolens L. in vitro culture
    H Ekiert
    Department of Pharmaceutical Botany, Jagiellonian University, Collegium Medicum, Faculty of Pharmacy, Krakow, Poland
    Pharmazie 64:694-6. 2009

Scientific Experts

Detail Information

Publications119 found, 100 shown here

  1. ncbi Effect of Ruta graveolens L. and Euphorbia peplus L. anti-inflammatory extracts on nutritional status of rats and the safety of their use
    Sahar Y Al-Okbi
    Food Sciences and Nutrition Department, National Research Centre, Dokki, Cairo, Egypt
    Indian J Exp Biol 40:45-8. 2002
    ..graveolens. The results suggest that both plant extracts have no harmful effect on nutritional status and are safe towards kidney functions, while Euphorbia is more safe than Ruta in relation to liver functions.
  2. ncbi Anti-tumour activity of Ruta graveolens extract
    K C Preethi
    Amala Cancer Research Centre, Amala Nagar, Thrissur, Kerala 680555, India
    Asian Pac J Cancer Prev 7:439-43. 2006
    An extract of Ruta graveolens was found to be cytotoxic to Dalton's lymphoma ascites (DLA), Ehrlich ascites carcinoma (EAC) and L929 cells in culture (IC100=16 mg/ml) and also to increase the lifespan of tumour bearing animals...
  3. ncbi Inhibition of lipopolysaccharide-inducible nitric oxide synthase and IL-1beta through suppression of NF-kappaB activation by 3-(1'-1'-dimethyl-allyl)-6-hydroxy-7-methoxy-coumarin isolated from Ruta graveolens L
    Sunil Kumar Raghav
    Proteomics and Structural Biology Division, Institute of Genomics and Integrative Biology, Delhi University Campus, Mall Road, Delhi 110 007, India
    Eur J Pharmacol 560:69-80. 2007
    The Ruta graveolens L. plant is used in traditional medicine to treat a large number of diseases...
  4. ncbi Anti-inflammatory effect of Ruta graveolens L. in murine macrophage cells
    S K Raghav
    Institute of Genomics and Integrative Biology, Delhi University Campus, Mall Road, Delhi 110007, India
    J Ethnopharmacol 104:234-9. 2006
    b>Ruta graveolens L. (Rutaceae) is used for several therapeutic purposes worldwide...
  5. pmc Ethnomedicines used in Trinidad and Tobago for reproductive problems
    Cheryl Lans
    BCICS, University of Victoria, British Columbia, V8W 2Y2, Canada
    J Ethnobiol Ethnomed 3:13. 2007
    ..Some folk uses are ancient and were documented by Galen and Pliny the Elder...
  6. doi Unusually divergent 4-coumarate:CoA-ligases from Ruta graveolens L
    Alexander Endler
    Institut fur Pharmazeutische Biologie, Philipps Universitat Marburg, Marburg, Germany
    Plant Mol Biol 67:335-46. 2008
    ..The common rue, Ruta graveolens L...
  7. ncbi Algicidal and antifungal compounds from the roots of Ruta graveolens and synthesis of their analogs
    Kumudini M Meepagala
    USDA ARS, Natural Products Utilization Research Unit, P O Box 8048, University, MS 38677, USA
    Phytochemistry 66:2689-95. 2005
    Bioassay-guided fractionation of the ethyl acetate extract of Ruta graveolens roots yielded rutacridone epoxide with potent selective algicidal activity towards the 2-methyl-isoborneol (MIB)-producing blue-green alga Oscillatoria ..
  8. ncbi Specific accumulation and revised structures of acridone alkaloid glucosides in the tips of transformed roots of Ruta graveolens
    Inna Kuzovkina
    Timiryazev Institute of Plant Physiology, Russian Academy of Sciences, Botanicheskaya ul 35, 127276 Moscow, Russia
    Phytochemistry 65:1095-100. 2004
    The root tips of Ruta graveolens (common rue) show strong autofluorescence of acridone alkaloids, which are characteristic secondary metabolites of this plant...
  9. ncbi Investigation of cytotoxic activity on human cancer cell lines of arborinine and furanoacridones isolated from Ruta graveolens
    Borbála Réthy
    Department of Pharmacodynamics and Biopharmacy, University of Szeged, Szeged, Hungary
    Planta Med 73:41-8. 2007
    The cytotoxic effects of a series of furanoacridones isolated from Ruta graveolens L...
  10. ncbi Free phenolic acids in Ruta graveolens L. in vitro culture
    H Ekiert
    Department of Pharmaceutical Botany, Jagiellonian University, Collegium Medicum, Faculty of Pharmacy, Krakow, Poland
    Pharmazie 64:694-6. 2009
    Eight phenolic acids were determined using HPLC method in methanolic extracts of Ruta graveolens L...
  11. doi Methanolic extract of Ruta graveolens L. inhibits inflammation and oxidative stress in adjuvant induced model of arthritis in rats
    M Ratheesh
    Department of Biochemistry, University of Kerala, Kariavattom, Thiruvananthapuram 695581, India
    Inflammopharmacology 17:100-5. 2009
    b>Ruta graveolens L. (Rutaceae) are traditionally used for the treatment of rheumatism, arthritis and other inflammatory conditions in the traditional medicine of India...
  12. doi A 2-oxoglutarate-dependent dioxygenase from Ruta graveolens L. exhibits p-coumaroyl CoA 2'-hydroxylase activity (C2'H): a missing step in the synthesis of umbelliferone in plants
    Guilhem Vialart
    UMR 1121 Lorraine University, INRA Agronomie et Environnement Nancy Colmar, ENSAIA, 2 Avenue de la Foret de Haye, 54505 Vandœuvre Lès Nancy, France
    Plant J 70:460-70. 2012
    ..approach and a cDNA library screen to identify an orthologous ORF (Genbank accession number JF799117) from Ruta graveolens L...
  13. pmc In silico target fishing for rationalized ligand discovery exemplified on constituents of Ruta graveolens
    Judith M Rollinger
    Institute of Pharmacy, Pharmacognosy, and Center for Molecular Biosciences, University of Innsbruck, 6020 Innsbruck, Austria
    Planta Med 75:195-204. 2009
    ..potential targets for 16 secondary metabolites isolated and identified from the aerial parts of the medicinal plant RUTA GRAVEOLENS L...
  14. ncbi Effect of Ruta graveolens L. on pregnant mice
    Tanise Gonçalves de Freitas
    Department of Morphological Sciences, Institute of Health Basic Sciences, Federal University of Rio Grande do Sul, Porto Alegre, RS90050 170, Brazil
    Contraception 71:74-7. 2005
    b>Ruta graveolens L. is used in many countries, including Brazil, as an abortifacient...
  15. ncbi Phytotoxins from the leaves of Ruta graveolens
    Amber L Hale
    Department of Pharmacognosy, University of Mississippi, University, Mississippi 38677, USA
    J Agric Food Chem 52:3345-9. 2004
    Bioassay-guided fractionation of the ethyl acetate extract of Ruta graveolens (common rue) leaves led to the isolation of the furanocoumarins 5-methoxypsoralen (5-MOP), 8-methoxypsoralen (8-MOP), and the quinolone alkaloid graveoline as ..
  16. doi Continuity and change in the Mediterranean medical tradition: Ruta spp. (rutaceae) in Hippocratic medicine and present practices
    A Pollio
    Dipartimento delle Scienze Biologiche, Sezione di Biologia Vegetale, University Federico II of Naples, Via Foria 223, 80139 Naples, Italy
    J Ethnopharmacol 116:469-82. 2008
    b>Ruta is a genus of Rutaceae family. It features mainly shrubby plants, native to the Mediterranean region and present in traditional medicine of this region since Antiquity. The three most diffused species Ruta chalepensis L...
  17. ncbi Ruta graveolens aqueous extract retards mouse preimplantation embryo development
    Jorge L Gutierrez-Pajares
    Laboratorio de Reproducción y Biología del Desarrollo, Facultad de Ciencias Biologicas, Universidad Nacional Mayor de San Marcos, Lima, Peru
    Reprod Toxicol 17:667-72. 2003
    This work was undertaken to examine possible embryotoxicity of Ruta graveolens (rue), a plant used by indigenous communities for the purposes of therapeutic and fertility regulation...
  18. ncbi Prolongation of AV nodal refractoriness by Ruta graveolens in isolated rat hearts. Potential role as an anti-arrhythmic agent
    Vahid Khori
    Golestan Cardiovascular Research Center, Faculty of Medicine, Golestan University of Medical Sciences, Golestan, Gorgan, Iran
    Saudi Med J 29:357-63. 2008
    To evaluate concentration-dependent effects of total extract of Ruta graveolens and its purified alkaloid fraction on the nodal basic and functional properties.
  19. ncbi Antimicrobial and cytotoxic activity of Ruta graveolens
    A Ivanova
    Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia 1113, Bulgaria
    Fitoterapia 76:344-7. 2005
    The methanol, petroleum ether, ethyl acetate and water-methanol extracts of Ruta graveolens were found to possess antimicrobial and cytotoxic activities.
  20. ncbi Potential allelochemicals from the essential oil of Ruta graveolens
    Vincenzo De Feo
    Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Salerno, Via Ponte Don Melillo, I 84084 Salerno, Fisciano, Italy
    Phytochemistry 61:573-8. 2002
    The essential oil of aerial parts of Ruta graveolens was obtained by hydrodistillation with a 0.74% yield on a dry weight basis. Thirty-eight components were identified by GC and GC-MS analyses...
  21. ncbi Natural fungicides from Ruta graveolens L. leaves, including a new quinolone alkaloid
    Anna Oliva
    Department of Life Science, Second University of Naples, Via Vivaldi 43, 81100 Naples, Italy
    J Agric Food Chem 51:890-6. 2003
    Bioassay-directed isolation of antifungal compounds from an ethyl acetate extract of Ruta graveolens leaves yielded two furanocoumarins, one quinoline alkaloid, and four quinolone alkaloids, including a novel compound, 1-methyl-2-[6'-(3' '..
  22. ncbi Cinnamic acid 4-hydroxylase mechanism-based inactivation by psoralen derivatives: cloning and characterization of a C4H from a psoralen producing plant-Ruta graveolens-exhibiting low sensitivity to psoralen inactivation
    Antoine Gravot
    UMR 1121 Agronomie Environnement INPL INRA, ENSAIA 2, Av de la Forêt de Haye, 54505 Vandoeuvre Les Nancy Cedex, France
    Arch Biochem Biophys 422:71-80. 2004
    Cinnamate 4-hydroxylase (C4H, EC 1.14.13.11) complete cDNA was cloned from the leaves of Ruta graveolens, a psoralen producing plant. The recombinant enzyme (classified CYP73A32) was expressed in Saccharomyces cerevisiae...
  23. ncbi Antiandrogenic activity of Ruta graveolens L in male Albino rats with emphasis on sexual and aggressive behavior
    Nabil Azar Khouri
    Department of Anatomy, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan
    Neuro Endocrinol Lett 26:823-9. 2005
    The Ruta graveolens L. is currently used by the Jordanian population systemically for its antispasmodic, diuretic, sedative, and analgesic effects and externally for its antirheumatic effect.
  24. ncbi Ruta 6 selectively induces cell death in brain cancer cells but proliferation in normal peripheral blood lymphocytes: A novel treatment for human brain cancer
    Sen Pathak
    Department of Molecular Genetics, M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Oncol 23:975-82. 2003
    ..We investigated the brain cancer cell-killing activity of a homeopathic medicine, Ruta, isolated from a plant, Ruta graveolens...
  25. ncbi Neuropharmacological profile of an ethanol extract of Ruta chalepensis L. in mice
    M E Gonzalez-Trujano
    Direccion de Investigaciones en Neurociencias del Instituto Nacional de Psiquiatria Ramon de la Fuente, Calz Mexico Xochimilco 101, Col Sn Lorenzo Huipulco, 14370 Mexico, D F, Mexico
    J Ethnopharmacol 106:129-35. 2006
    The effects of an ethanol extract of the aerial parts of Ruta chalepensis on the central nervous system (CNS) and LD(50) determination were studied in mice...
  26. ncbi Inhibitory effects of Ruta graveolens L. extract on guinea pig liver aldehyde oxidase
    Saieed Pirouzpanah
    School of Health and Nutrition, Tabriz University of Medical Sciences, Iran
    Chem Pharm Bull (Tokyo) 54:9-13. 2006
    b>Ruta graveolens L. is a flavonoid-containing medicinal plant with various biological properties. In the present study, the effects of R. graveolens extract on aldehyde oxidase, a molybdenum hydroxylase, are investigated...
  27. ncbi Phytochemical studies on Ruta chalepensis (Lam.) Lamarck
    Keriman Günaydin
    Department of Chemistry, Faculty of Liberal Arts and Sciences, Mustafa Kemal University, 31024, Hatay, Turkey
    Nat Prod Res 19:203-10. 2005
    b>Ruta chalepensis is a rich source of important secondary metabolites such as furanocoumarins and alkaloids. Besides, it is a medicinal plant and still used in traditional medicine...
  28. ncbi Combinatorial synthesis by nature: volatile organic sulfur-containing constituents of Ruta chalepensis L
    Sina Escher
    Firmenich SA, Corporate R and D Division, P O Box 239, CH 1211 Geneva 8
    Chem Biodivers 3:943-57. 2006
    ..new natural fragrance and flavor ingredients prompted us to examine a solvent extract of sulfurous-sweaty smelling Ruta chalepensis L. (Rutaceae) plant material more closely...
  29. ncbi Medicinal plant use in the Bredasdorp/Elim region of the Southern Overberg in the Western Cape Province of South Africa
    T S A Thring
    Department of Biodiversity and Conservation Biology, University of the Western Cape, Private Bag X17, Bellville 7535, South Africa
    J Ethnopharmacol 103:261-75. 2006
    ..A more structured questionnaire was used to determine which plants were most popular for particular ailments. It was found that Artemisia afra and Ruta graveolens were the most popular.
  30. ncbi Preliminary observations on experimental Ruta graveolens toxicosis in Nubian goats
    S E I el Agraa
    Department of Veterinary Medicine, Pharmacology and Toxicology, University of Khartoum, PO Box 32, Khartoum North, Sudan
    Trop Anim Health Prod 34:271-81. 2002
    We present the first reported study of Ruta graveolens toxicity in 7-8-month-old Nubian goats. Oral administration of 5 g/kg bw per day of R...
  31. ncbi Rue the herb: Ruta graveolens--associated phytophototoxicity
    Kimberly Eickhorst
    Department of Dermatology, St Luke s Roosevelt Hospital, New York, NY, USA
    Dermatitis 18:52-5. 2007
    We describe an unusual case of phytophototoxicity induced by an herbal plant, Ruta graveolens, from the Rutaceae family. This common herb, also called rue, can be found throughout rural settings in the United States...
  32. ncbi Ethnoveterinary medicines used to treat endoparasites and stomach problems in pigs and pets in British Columbia, Canada
    Cheryl Lans
    BCICS, University of Victoria, British Columbia V8W 2Y2, Canada
    Vet Parasitol 148:325-40. 2007
    ..Ranunculaceae), Juglans nigra L. (Juglandaceae), Olea europaea L. (Oleaceae) and Ruta graveolens L. (Rutaceae)). Stomach problems were treated with: Achillea millefolium L. (Asteraceae), Aloe vera (L...
  33. ncbi Comparative study of the assay of Artemia salina L. and the estimate of the medium lethal dose (LD50 value) in mice, to determine oral acute toxicity of plant extracts
    A Logarto Parra
    Drug Research and Development Center CIDEM, Biologic Research Department, Ciudad de La Habana, Cuba
    Phytomedicine 8:395-400. 2001
    ..Plantaginaceae); Plectranthus amboinicus (Lour.) Spreng. (Lamiaceae); Ruta graveolens L. (Rutaceae); Senna alata (L.) Roxb. (Fabaceae); Stachytarpheta jamaicensis (L...
  34. ncbi The ecological aspect of ethnobotany and ethnopharmacology of population in Bosnia and Herzegovina
    Sulejman S Redzić
    Center of Ecology and Natural Resources, Faculty of Science University of Sarajevo, Sarajevo, Bosnia and Herzegovina
    Coll Antropol 31:869-90. 2007
    ..asclepiadea, Helichrysum italicum, Lycopodium clavatum, Marrubium vulgare, Nepeta cataria, Populus tremula, Ruta graveolens, Tamus communis, Teucrium montanum, T. chamaedrys, and endemic plants Gentiana lutea subsp...
  35. ncbi Compounds from Ageratum conyzoides: isolation, structural elucidation and insecticidal activity
    Márcio D Moreira
    Departamento de Biologia Animal, Universidade Federal de Vicosa, Vicosa, MG 36571 000, Brazil
    Pest Manag Sci 63:615-21. 2007
    ..Coleoptera: Bostrichidae). The plant species used were: basil (Ocimum selloi Benth.), rue (Ruta graveolens L.), lion's ear (Leonotis nepetaefolia L.), Jimson weed (Datura stramonium L...
  36. doi Repellent activity of plant-derived compounds against Amblyomma cajennense (Acari: Ixodidae) nymphs
    Sara Fernandes Soares
    Centro de Parasitologia Veterinária, Escola de Veterinaria, Universidade Federal de Goias UFG, Campus II Samambaia, Caixa Postal 131, 74001 970 Goiania, GO, Brazil
    Vet Parasitol 167:67-73. 2010
    ..Cymbopogon nardus, Spiranthera odoratissima, Chenopodium ambrosioides, Ageratum conyzoides, Mentha pulegium, Ruta graveolens, and Memora nodosa were studied. Among these the extract of C...
  37. ncbi In vitro susceptibility of Entamoeba histolytica and Giardia lamblia to plants used in Mexican traditional medicine for the treatment of gastrointestinal disorders
    Fernando Calzada
    Unidad de Investigación Médica en Farmacología de Productos Naturales, Hospital de Pediatria, 2 Piso, Centro Medico Nacional Siglo XXI, IMSS, Av Cuauhtemoc 330, Col Doctores, CP 06725, Mexico, DF, Mexico
    J Ethnopharmacol 108:367-70. 2006
    ..Dorstenia contrajerva, Senna villosa and Ruta chalepensis were the most active toward Giardia lamblia with IC50 < 38 microg/ml...
  38. ncbi An acridone-producing novel multifunctional type III polyketide synthase from Huperzia serrata
    Kiyofumi Wanibuchi
    School of Pharmaceutical Sciences and the COE 21 Program, University of Shizuoka, Japan
    FEBS J 274:1073-82. 2007
    ..Interestingly, Hu. serrata polyketide synthase 1 lacks most of the consensus active site sequences with acridone synthase from Ruta graveolens (Rutaceae).
  39. ncbi Effects of ephedrine and phenylephrine on uterine and placental circulations and fetal outcome following fetal hypoxaemia and epidural-induced hypotension in a sheep model
    T Erkinaro
    Department of Anaesthesiology, University Hospital of Oulu, PO Box 21, FIN 90029 OYS, Finland
    Br J Anaesth 93:825-32. 2004
    ..We hypothesized that ephedrine and phenylephrine, administered for maternal hypotension following fetal hypoxaemia, are equal in respect of fetal outcome...
  40. ncbi 'Translation is not enough': using the Global Person Generated Index (GPGI) to assess individual quality of life in Bangladesh, Thailand, and Ethiopia
    Laura Camfield
    Wellbeing in Developing Countries ESRC Research Group, University of Bath, Bath BA2 7AY, UK
    Qual Life Res 16:1039-51. 2007
    ..The GPGI is based on the widely used Patient Generated Index (Ruta, Camfield, & Martin, (2004) Quality of Life Research, 13, 1545...
  41. doi Phylogenetic relationships of Ruteae (Rutaceae): new evidence from the chloroplast genome and comparisons with non-molecular data
    Gabriele Salvo
    Institute of Systematic Botany, University of Zurich, Zollikerstrasse 107, Ch 8008 Zurich, Switzerland
    Mol Phylogenet Evol 49:736-48. 2008
    ..The phylogenetic analyses determined that Haplophyllum and Ruta form reciprocally exclusive monophyletic groups and that Dictamnus is not closely related to the other genera of ..
  42. doi Evaluation of antileishmanial, cytotoxic and antioxidant activities of essential oils extracted from plants issued from the leishmaniasis-endemic region of Sned (Tunisia)
    S Ben Hadj Ahmed
    Departement de Biologie, Faculté des Sciences de Gafsa, Campus Universitaire Zarroug Gafsa 2112, Gafsa, Tunisia
    Nat Prod Res 25:1195-201. 2011
    ..62% and camphor at 13.82%) is significantly active against both L. major and L. infantum, whereas Ruta chalepensis EO (rich on 2-undecanone at 84.28%) is only active against L. infantum...
  43. ncbi Molluscicidal activity of some Moroccan medicinal plants
    M Hmamouchi
    Unité de recherche Substances Naturelles, Faculte de Medecine et de Pharmacie, Rabat, B P 6203, Rabat Institut, Maroc
    Fitoterapia 71:308-14. 2000
    ..activity, ethyl acetate extract from Origanum compactum and hexane extracts from both Chenopodium ambrosioides and Ruta chalepensis were the most active (LC(90)=2.00, 2.23 and 2...
  44. ncbi Transvaginal Doppler-guided uterine artery occlusion for the treatment of symptomatic fibroids: summary results from two pilot studies
    George A Vilos
    Department of Obstetrics and Gynecology, St Joseph s Health Care, London, ON
    J Obstet Gynaecol Can 32:149-54. 2010
    ..To evaluate the feasibility, safety, and short-term efficacy of bilateral uterine artery occlusion, using a transvaginal Doppler-guided vascular clamp as a minimally invasive therapy for symptomatic uterine leiomyomas...
  45. ncbi [Toxic hepatitis due to the use of Ruta herbal medicine]
    Elena Rabaev
    Department of Family Medicine, Dimona Dalet Clalit Health Services, Beer Sheba, Israel
    Harefuah 150:235-6, 305. 2011
    ..In this case report, we present an example of toxic hepatitis due to use of Ruta herbal medicine, an unfamiliar side effect of the common herbal medicine Ruta.
  46. ncbi Purification and properties of acridone synthase from cell suspension cultures of Ruta graveolens L
    A Baumert
    , Halle Saale, Bundesrepublik Deutschland
    Z Naturforsch C 49:26-32. 1994
    Acridone synthase has been purified from cell suspension cultures of Ruta graveolens using a combination of gel filtration and ion exchange chromatography...
  47. ncbi Long-term outcome from uterine fibroid embolization with tris-acryl gelatin microspheres: results of a multicenter study
    James B Spies
    Department of Radiology, Georgetown University Hospital, 3800 Reservoir Rd NW, CG 201, Washington, DC 20007 2197, USA
    J Vasc Interv Radiol 18:203-7. 2007
    ..To determine the long-term outcome of uterine fibroid therapy (UFE) using tris-acryl gelatin microspheres (TAGM)...
  48. pmc Ruta graveolens L. toxicity in Vampirolepis nana infected mice
    R B Freire
    Department of Environmental Technology, Universidade tecnológica Federal do Paraná, Campus Medianeira, Avenida Brasil 4232, Medianeira, PR, 85884000, Brazil
    Indian J Pharmacol 42:345-50. 2010
    To determine possible toxic effects of Ruta graveolens hydroalcoholic extract in gastrointestinal parasitic infection.
  49. ncbi Deletion analysis of the Escherichia coli rho-dependent transcription terminator trp t'
    F Zalatan
    Department of Biology, University of Rochester, New York 14642
    J Biol Chem 268:17051-6. 1993
    ..that together appear to be important for full transcription termination efficiency in vitro and are similar to the rutA and rutB sequence elements in the lambda tR1 rho-dependent terminator previously described by Chen and Richardson (..
  50. ncbi Oxidative profile in patients with colon cancer: effects of Ruta chalepensis L
    R Acquaviva
    Department of Biochemistry, Medical Chemistry and Molecular Biology, University of Catania, Catania, Italy
    Eur Rev Med Pharmacol Sci 15:181-91. 2011
    To verify the involvement of free radicals in tumor progression and to investigate the effects of an ethanolic extract of Ruta Chalepensis L. and of rutin in blood of patients with colon cancer.
  51. ncbi Inhibition of chemically induced carcinogenesis by drugs used in homeopathic medicine
    K B Hari Kumar
    Amala Cancer Research Centre, Amala Nagar, Thrissur, Kerala State, India
    Asian Pac J Cancer Prev 8:98-102. 2007
    ..We have used Ruta, Hydrastis, Lycopodium and Thuja, which are commonly employed in homeopathy for treating cancer...
  52. pmc A previously undescribed pathway for pyrimidine catabolism
    Kevin D Loh
    Department of Plant and Microbial Biology, 111 Koshland Hall, University of California, Berkeley, CA 94720 3102, USA
    Proc Natl Acad Sci U S A 103:5114-9. 2006
    ..We propose that the genes of this operon be named rutA-G for pyrimidine utilization...
  53. ncbi An improved assay for the detection of alterations in bacterial DNA supercoiling in vivo
    M Abu Mraheil
    Pharmaceutical Biology and Microbiology, University of Hamburg, Germany
    Pharmazie 68:541-8. 2013
    ....
  54. doi Bioactivity against Bursaphelenchus xylophilus: Nematotoxics from essential oils, essential oils fractions and decoction waters
    Jorge M S Faria
    Universidade de Lisboa, Faculdade de Ciencias de Lisboa, DBV, IBB, Centro de Biotecnologia Vegetal, C2, Campo Grande, 1749 016 Lisboa, Portugal
    Phytochemistry 94:220-8. 2013
    ..Twenty EOs showed corrected mortalities ⩾96% at 2 μL/mL. These were further tested at lower concentrations. Ruta graveolens, Satureja montana and Thymbra capitata EOs showed lethal concentrations (LC100)<0.4μL/mL...
  55. ncbi [Transformation of the names of certain herbs by linguistic transfer - colchicum, wormseed, soybean, nandina and wijnruit]
    Masao Uchibayashi
    Yakushigaku Zasshi 39:350-4. 2004
    ..and soybeans, (4) from the Japanese plant nanten to the genus Nandina, and (5) from the Dutch term wijnruit (wine-ruta) to hen-ruda in Japanese...
  56. ncbi Furanocoumarin biosynthesis in Ammi majus L. Cloning of bergaptol O-methyltransferase
    Marc Hehmann
    Institut fur Pharmazeutische Biologie, Philipps Universitat Marburg, Germany
    Eur J Biochem 271:932-40. 2004
    ..had been reported to methylate bergaptol to bergapten and xanthotoxol to xanthotoxin, from induced cell cultures of Ruta graveolens, Petroselinum crispum and Ammi majus...
  57. ncbi Field trials on the repellent activity of four plant products against mainly Mansonia population in western Ethiopia
    Mamuye Hadis
    Ethiopian Health and Nutrition Research Institute, PO Box 1242, Addis Ababa, Ethiopia
    Phytother Res 17:202-5. 2003
    The repellent activity of essential oils of lemon eucalyptus (Eucalyptus maculata citrodion), rue (Ruta chalepensis), oleoresin of pyrethrum (Chrysanthemum cinerariaefolium) and neem (Azadiracta indica) have been field tested as 40%, 50% ..
  58. doi Furanocoumarins: novel topoisomerase I inhibitors from Ruta graveolens L
    Renuka Diwan
    Department of Botany, University of Pune, Pune 411007, Maharashtra, India
    Bioorg Med Chem 17:7052-5. 2009
    Topoisomerase I inhibitors from Ruta graveolens are reported for the first time. Potent topoisomerase I inhibitory activity from in vitro culture extracts R. graveolens were observed...
  59. ncbi Evaluating companion planting and non-host masking odors for protecting roses from the Japanese beetle (Coleoptera: Scarabaeidae)
    D W Held
    Department of Entomology, University of Kentucky, Lexington, KY 40546 0091, USA
    J Econ Entomol 96:81-7. 2003
    ..Three reputedly effective companion species, rue (Ruta graveolens L.), zonal geranium (Pelargonium x hortorum Bailey), and garlic chives (Allium scheonparum L...
  60. ncbi Perinatal toxicology of Ruta chalepensis (Rutaceae) in mice
    R Zeichen de Sa
    Departamento de Farmacologia, Instituto Nacional de Medicamentos, Administración Nacional de Medicamentos, Alimentos y Tecnología Médica, Buenos Aires, Argentina
    J Ethnopharmacol 69:93-8. 2000
    Dried leaf infusions of Ruta chalepensis L. (Rutaceae), 'rue', 'ruda', were found to cause perinatal changes in mice, at daily doses of 0.16, 0.80 and 1.60 g/kg, administered p.o. from 1 to 14 days post coitum...
  61. doi Oral administration of alkaloid fraction from Ruta graveolens inhibits oxidative stress and inflammation in hypercholesterolemic rabbits
    M Ratheesh
    Department of Biochemistry, University of Kerala, Thiruvananthapuram, India
    Pharm Biol 51:1552-8. 2013
    The anti-atherogenic effect of alkaloid fraction from Ruta graveolens Linn (Rutaceae) extract is suspected to be related to its activities of antioxidation and anti-inflammation.
  62. doi Induction of apoptosis of tumor cells by some potentiated homeopathic drugs: implications on mechanism of action
    Korengath Preethi
    Amala Cancer Research Centre, Thrissur, Kerala, India
    Integr Cancer Ther 11:172-82. 2012
    ..Earlier studies indicated that homoeopathic medicines are cytotoxic to tumor cells and reduced animal tumors. However, the mechanism of homoeopathic medicines at the cellular level is not known...
  63. doi Chemical composition and antimicrobial activity of the essential oils from four Ruta species growing in Algeria
    Farah Haddouchi
    Laboratory of Natural Products, Department of Biology, Faculty of Sciences, Abou Bekr Belkaid University, B P 119, Tlemcen 13000, Algeria
    Food Chem 141:253-8. 2013
    ..of this research is to study the antibacterial and antifungal effects of four traditional plants essential oils, Ruta angustifolia, Ruta chalepensis, Ruta graveolens and Ruta tuberculata, against standard bacterial and fungal strains...
  64. pmc CYP98A22, a phenolic ester 3'-hydroxylase specialized in the synthesis of chlorogenic acid, as a new tool for enhancing the furanocoumarin concentration in Ruta graveolens
    Fazeelat Karamat
    Université de Lorraine UMR 1121, Agronomie et Environnement Nancy Colmar, ENSAIA 2 avenue de la forêt de Haye, 54505 Vandœuvre Lès Nancy, France
    BMC Plant Biol 12:152. 2012
    ..with proven therapeutic properties and are produced in only a small number of medicinal plant species such as Ruta graveolens. In vivo, these molecules play a protective role against phytophageous insect attack...
  65. ncbi Effect of polyamines on shoot multiplication and furanocoumarin production in Ruta graveolens cultures
    Renuka Diwan
    Department of Botany, University of Pune, India
    Nat Prod Commun 7:895-8. 2012
    ..furanocoumarin production was investigated by exogenous addition, at different concentrations, to shoot cultures of Ruta graveolens at different phases of growth...
  66. doi Anti-inflammatory effect of quinoline alkaloid skimmianine isolated from Ruta graveolens L
    M Ratheesh
    Department of Biochemistry, Kerala University, Trivandrum, India
    Inflamm Res 62:367-76. 2013
    The present study evaluates the anti-inflammatory effect of the quinoline alkaloid skimmianine (SKM), isolated from Ruta graveolens L., against carrageenan-induced acute inflammation.
  67. ncbi [Effects of ruta SSP on the activity of the smooth gastrointestinal muscle isolated of rat]
    Carlota A Grigorjev
    Cátedra de Farmacología General Escuela Práctica Facultad de Ciencias Médicas Universidad Nacional de Córdoba Santa Rosa 1085, 5000 Cordoba, Argentina
    Rev Fac Cien Med Univ Nac Cordoba 67:77-80. 2010
    b>Ruta graveolens L. and Ruta chalepensis L. are plants used in folkloric medicine as antispasmodics, digestive and for intestinal gases...
  68. pmc Catalysis of a flavoenzyme-mediated amide hydrolysis
    Tathagata Mukherjee
    Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, USA
    J Am Chem Soc 132:5550-1. 2010
    ..The seven-gene Rut operon is required for this conversion. Here we demonstrate that the flavoenzyme RutA catalyzes the initial uracil ring-opening reaction to give 3-ureidoacrylate...
  69. doi Molecular authentication of the medicinal herb Ruta graveolens (Rutaceae) and an adulterant using nuclear and chloroplast DNA markers
    F Al-Qurainy
    Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia
    Genet Mol Res 10:2806-16. 2011
    ..b>Ruta graveolens, sold as a dried medicinal herb, can be adulterated with Euphorbia dracunculoides...
  70. doi Inhibitory effect of Ruta graveolens L. on oxidative damage, inflammation and aortic pathology in hypercholesteromic rats
    M Ratheesh
    Department of Biochemistry, University of Kerala, Kariavattom, Thiruvananthapuram 695 581, India
    Exp Toxicol Pathol 63:285-90. 2011
    The purpose of the study was to investigate the efficacy of methanolic extract of Ruta graveolens L. in reducing oxidative damage, inflammation and aortic pathology in hypercholesteremic rats...
  71. ncbi High-resolution gas-chromatographic analysis of the secondary metabolites obtained by subcritical-fluid extraction from Colombian rue (Ruta graveolens L.)
    E E Stashenko
    Phytochemistry and Chromatography Laboratory, School of Chemistry, Industrial University of Santander, A A 678, Bucaramanga, Colombia
    J Biochem Biophys Methods 43:379-90. 2000
    ..Extractor, was used to isolate secondary metabolites from leaves, flowers, stems and roots of Colombian rue (Ruta graveolens L.)...
  72. ncbi Intracranial cysticercosis: an effective treatment with alternative medicines
    P Banerji
    PBH Research Foundation, 10 3 1 Elgin Road, Calcutta 700 020, West Bengal, India
    In Vivo 15:181-4. 2001
    The purpose of this study was to demonstrate the cysticidal activities of Ruta graveolens and calcium phosphate in fractional dilutions as a completely new approach for the treatment of neurocysticercosis in humans...
  73. doi Protective effects of isolated polyphenolic and alkaloid fractions of Ruta graveolens L. on acute and chronic models of inflammation
    M Ratheesh
    Department of Biochemistry, University of Kerala, Kariavattom, Thiruvananthapuram 695 581, India
    Inflammation 33:18-24. 2010
    b>Ruta graveolens L...
  74. doi Floral ontogeny of Ruteae (Rutaceae) and its systematic implications
    L Wei
    State Key Laboratory of Systematic and Evolutionary Botany, Institute of Botany, Chinese Academy of Sciences, Xiangshan, Beijing, China
    Plant Biol (Stuttg) 14:190-7. 2012
    Floral development was investigated in Ruta graveolens and Psilopeganum sinense, representing two genera in the tribe Ruteae. Special attention was paid to the sequence of initiation of organ whorls in the androecium and gynoecium...
  75. ncbi Cell cycle analysis and cytotoxic potential of Ruta graveolens against human tumor cell lines
    P Varamini
    Shiraz Institute for Cancer Research, Shiraz Univeristy of Medical Sciences, Shiraz, Iran
    Neoplasma 56:490-3. 2009
    There are reports on the presence of various compounds exerting different biological activities in Ruta graveolens, a plant of Rutaceae family. The aim of the present study was to evaluate in vitro cytotoxicity of the total extract of R...
  76. pmc The Rut pathway for pyrimidine degradation: novel chemistry and toxicity problems
    Kwang Seo Kim
    Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720 3102, USA
    J Bacteriol 192:4089-102. 2010
    ..The RutA and RutB proteins are central: no spontaneous suppressors arise in strains lacking them...
  77. ncbi [Phagodeterrence by a crude extract of common rue (Ruta chalepensis, Rutaceae) and its partitions on Hypsipyla grandella (Lepidoptera: Pyralidae) larvae]
    Javier Barboza
    Escuela de Quimica, Universidad Nacional, Heredia, Costa Rica
    Rev Biol Trop 58:1-14. 2010
    ..In the search for a preventative method for managing it, the crude leaf extract of common rue (Ruta chalepensis L...
  78. pmc Ruta graveolens extract induces DNA damage pathways and blocks Akt activation to inhibit cancer cell proliferation and survival
    Khalda Fadlalla
    Department of Pathobiology, Center for Cancer Research, Tuskegee, AL 36088, USA
    Anticancer Res 31:233-41. 2011
    b>Ruta graveolens is a medicinal herb that has been used for centuries against various ailments. This study examined the anticancer properties of the herb using cancer cell lines.
  79. ncbi A new dicoumarinyl ether and two rare furocoumarins from Ruta montana
    Z Kabouche
    Université Mentouri Constantine, Faculte des Sciences, Laboratoire d Obtention de Substances Thérapeutiques L O S T, Campus Chaabet Ersas, Constantine 25000, Algerie
    Fitoterapia 74:194-6. 2003
    A new dicoumarinyl ether, rutamontine and two rare furocoumarins, heraclenol and isopimpinellin, were isolated from Ruta montana...
  80. doi Bioprocess optimization of furanocoumarin elicitation by medium renewal and re-elicitation: a perfusion-based approach
    Renuka Diwan
    Department of Botany, University of Pune, Maharashtra, India
    Appl Biochem Biotechnol 163:756-64. 2011
    ..niger) elicitors on furanocoumarin production and in situ product removal was studied using shoot cultures of Ruta graveolens L. Elicitation by yeast extract (1% w/v) on day 15 was most effective. It led to 7...
  81. doi Tracing the temporal and spatial origins of island endemics in the Mediterranean region: a case study from the citrus family (Ruta L., Rutaceae)
    Gabriele Salvo
    Institute of Systematic Botany, University of Zurich, Zurich, Switzerland
    Syst Biol 59:705-22. 2010
    ..including the Mediterranean basin and Macaronesia) provides the geographic backdrop for the diversification of Ruta L., the type genus of Rutaceae (citrus family)...
  82. doi Aliphatic ketones from Ruta chalepensis (Rutaceae) induce paralysis on root knot nematodes
    Nikoletta G Ntalli
    Department of Pharmaceutical Chemistry and Technology, University of Cagliari, Cagliari, Italy
    J Agric Food Chem 59:7098-103. 2011
    This paper reports on the use of Ruta chalepensis L. extracts as a potential nematicide against root knot nematodes Meloidogyne incognita and Meloidogyne javanica . The essential oil (REO) and methanol extract (RME) of R...
  83. doi Quality of life in women with bleeding disorders
    S Von Mackensen
    Institute for Medical Psychology and Policlinics, Centre of Psychosocial Medicine, University Medical Centre of Hamburg Eppendorf, Hamburg, Germany
    Haemophilia 17:33-7. 2011
    ..instruments are available for the adequate assessment of the impact of menorrhagia on HRQOL, namely the Ruta Menorrhagia Severity Scale, the menorrhagia multi-attribute utility scale and the Menorrhagia Impact Questionnaire...
  84. ncbi Accumulation of biologically active furanocoumarins in Ruta graveolens ssp. divaricata (Tenore) Gams in vitro culture
    H Ekiert
    Department of Pharmaceutical Botany, Collegium Medicum, Jagiellonian University, Krakow, Poland
    Pharmazie 60:66-8. 2005
    ..dynamics of accumulation of five linear furanocoumarins and umbelliferone in stationary liquid cultures of Ruta graveolens ssp. divaricata (Tenore) Gams during 6-week growth cycles...
  85. ncbi [Phagodeterrent and systemic activity of a fomulation derived from an extract of common rue (Ruta chalepensis, Rutaceae) on Hypsipyla grandella (Lepidoptera: Pyralidae) larvae]
    Javier Barboza
    Escuela de Quimica, Universidad Nacional, Heredia, Costa Rica
    Rev Biol Trop 58:15-29. 2010
    ..Since crude extracts of common rue foliage (Ruta chalepensis L.) have phagodeterrent activity on H...
  86. pmc Effect of Ruta graveolens and Cannabis sativa alcoholic extract on spermatogenesis in the adult wistar male rats
    M R Sailani
    Department of Biology, Faculty of Sciences, Isfahan University, Isfahan, Iran
    Indian J Urol 23:257-60. 2007
    The present study was undertaken to evaluate the effects of alcohol extracts of Ruta graveolens and Cannabis sativa that were used traditionally in medieval Persian medicine as male contraceptive drugs, on spermatogenesis in the adult ..
  87. ncbi Evaluation of antimicrobial activity of selected plant extracts by rapid XTT colorimetry and bacterial enumeration
    Amal G Al-Bakri
    Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, University of Jordan, Amman 11942, Jordan
    J Microbiol Methods 68:19-25. 2007
    ..The plant extracts of Hypericum triquetrifolium, Ballota undulata, Ruta chalepensis, Ononis natrix, Paronychia argentea and Marrubium vulgare had shown promising antimicrobial activity...
  88. ncbi Protection against murine endotoxemia by treatment with Ruta chalepensis L., a plant with anti-inflammatory properties
    Liliana Iauk
    Department of Microbiological and Gynaecological Sciences, Section of Microbiology, University of Catania, Via Androne 81, Catania 95124, Italy
    J Ethnopharmacol 90:267-72. 2004
    The anti-inflammatory effect of the extract of Ruta Chalepensis L. (Rutaceae) on the course of lethal endotoxemia in BALB/c mice was studied. When administered by gavage as 1 g/kg per day starting 14 or 7 days prior to injection of 0...
  89. ncbi Temporary uterine artery occlusion for treatment of menorrhagia and uterine fibroids using an incisionless Doppler-guided transvaginal clamp: case report
    G A Vilos
    Department of Obstetrics and Gynecology, University of Western Ontario, St Joseph s Health Care, London, Ontario, Canada
    Hum Reprod 21:269-71. 2006
    ..Menorrhagia symptoms were tracked with the Ruta Menorrhagia Severity Scale. Uterine and fibroid volumes were measured by analysis of magnetic resonance images...
  90. ncbi Anthranilate N-methyltransferase, a branch-point enzyme of acridone biosynthesis
    Britta Rohde
    Institut fur Pharmazeutische Biologie, Philipps Universitat Marburg, Deutschhausstrasse 17A, 35037 Marburg, Germany
    Plant J 53:541-53. 2008
    Acridone alkaloids formed by acridone synthase in Ruta graveolens L. are composed of N-methylanthraniloyl CoA and malonyl CoAs...
  91. ncbi Effective biotic elicitation of Ruta graveolens L. shoot cultures by lysates from Pectobacterium atrosepticum and Bacillus sp
    A Orlita
    Faculty of Chemistry, University of Gdansk, ul Sobieskiego 18, Gdansk, Poland
    Biotechnol Lett 30:541-5. 2008
    Growth of Ruta graveolens shoots was induced when Bacillus sp. cell lysates were added to the culture medium...
  92. ncbi Herb of grace: an unusual cause of phytophotodermatitis mimicking burn injury
    Dominic Furniss
    Department of Plastic and Reconstructive Surgery, The West Wing, John Radcliffe Hospital, Oxford, United Kingdom
    J Burn Care Res 28:767-9. 2007
    ..of a 2-year-old child who suffered an acute phytophotodermatitis with systemic upset after contact with the herb Ruta Graveolens (common rue, Herb of Grace)...
  93. ncbi Isoflavones in the Rutaceae family: twenty selected representatives of the genera Citrus, Fortunella, Poncirus, Ruta and Severinia
    Radka Koblovska
    Department of Chemistry of Natural Compounds, Institute of Chemical Technology, Prague, Czech Republic
    Phytochem Anal 19:64-70. 2008
    ..Species belonging to five genera were studied, namely Citrus, Fortunella, Poncirus, Ruta and Severinia...
  94. ncbi A new coumarin glucoside, coumarins and alkaloids from Ruta corsica roots
    Cedric Bertrand
    Laboratoire Pharmacophores Redox, Phytochimie et Radiobiologie, EA 3030 Faculté des Sciences Pharmaceutiques, Université Paul Sabatier 35, chemin des Maraichers, 310362 Toulouse 4, France
    Fitoterapia 75:242-4. 2004
    ..one coumarin, five furanocoumarins, three bicoumarins, three quinoline alkaloids and one sinapoyl sucrose derivative have been isolated from the roots of Ruta corsica.
  95. ncbi Volatile components of some Rutaceae species
    Antoaneta Ivanova
    Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia 1113, Bulgaria
    Z Naturforsch C 59:169-73. 2004
    The volatile components of the aerial parts of Ruta graveolens and Haplophyllum suaveolens, as well as of leaves of Zanthoxylum limoncello, Z. panamense and Z. setulosum have been studied by GC/MS analysis.
  96. ncbi Mutagenicity testing of rutacridone epoxide and rutacridone, alkaloids in Ruta graveolens L., using the Salmonella/microsome assay
    H Paulini
    Institut fúr Botanik und Pharmazeutische Biologie der Universität Erlangen Nürnberg, FRG
    Mutagenesis 4:45-50. 1989
    ..Evidence is presented that rutacridone is metabolized by rat liver enzymes to the corresponding epoxide as the ultimate mutagen...
  97. ncbi Ruta Graveolens intoxication
    Chen June Seak
    Department of Emergency Medicine, Chang Gung Memorial Hospital, Linkou, Taiwan
    Clin Toxicol (Phila) 45:173-5. 2007
    We describe a case of unintentional poisoning from Ruta Graveolens, a medicinal herb that is used for heart protection in Taiwan...
  98. ncbi Unusual pseudosubstrate specificity of a novel 3,5-dimethoxyphenol O-methyltransferase cloned from Ruta graveolens L
    Laura Burga
    Institut fur Pharmazeutische Biologie, Philipps Universitat Marburg, Deutschhausstrasse 17A, D 35037 Marburg, Germany
    Arch Biochem Biophys 440:54-64. 2005
    A cDNA was cloned from Ruta graveolens cells encoding a novel O-methyltransferase (OMT) with high similarity to orcinol or chavicol/eugenol OMTs, but containing a serine-rich N-terminus and a 13 amino acid insertion between motifs IV and ..
  99. ncbi Identification of Ruta graveolens L. metabolites accumulated in the presence of abiotic elicitors
    Aleksandra Orlita
    Faculty of Chemistry, University of Gdansk, PL 80 952 Gdansk, ul Sobieskiego 18, Gdansk, Poland
    Biotechnol Prog 24:128-33. 2008
    ..The use of saccharin also increased the production of bergapten, isopimpinelin, pinnarin, psoralen, and xanthotoxin several times...
  100. ncbi Effect of homeopathic medicines on transplanted tumors in mice
    Sunila Es
    Amala Cancer Research Centre, Amala Nagar, Thrissur, Kerala State, India 680555
    Asian Pac J Cancer Prev 8:390-4. 2007
    ..It was found that Ruta graveolens 200c and Hydrastis canadensis 200c significantly increased the lifespan of Ehrlich Ascites Carcinoma and ..
  101. pmc Effect of homeopathy on analgesic intake following knee ligament reconstruction: a phase III monocentre randomized placebo controlled study
    A Paris
    INSERM, CIC003, CHU Grenoble, Grenoble F 38043, Grenoble, France
    Br J Clin Pharmacol 65:180-7. 2008
    ..complex of homeopathy tested in this study (Arnica montana 5 CH, Bryonia alba 5 CH, Hypericum perforatum 5 CH and Ruta graveolens 3 DH) is not superior to placebo in reducing 24 h morphine consumption after knee ligament reconstruction...

Research Grants5

  1. GENETIC STUDIES OF GLUTAMINE SYNTHETASE IN BACTERIA
    Sydney Kustu; Fiscal Year: 2007
    ..and biochemical approaches to identify the intermediates of the Rut pathway and the enzymatic activities of the RutA-RutF proteins. We will study the DNA binding and transcriptional repression activities of RutR in vitro...
  2. GENETIC STUDIES OF GLUTAMINE SYNTHETASE IN BACTERIA
    Sydney Kustu; Fiscal Year: 2009
    ..and biochemical approaches to identify the intermediates of the Rut pathway and the enzymatic activities of the RutA-RutF proteins. We will study the DNA binding and transcriptional repression activities of RutR in vitro...
  3. GENETIC STUDIES OF GLUTAMINE SYNTHETASE IN BACTERIA
    SYDNEY GOVONS KUSTU; Fiscal Year: 2010
    ..and biochemical approaches to identify the intermediates of the Rut pathway and the enzymatic activities of the RutA-RutF proteins. We will study the DNA binding and transcriptional repression activities of RutR in vitro...
  4. Small Molecule Kv1.3 Blockers as New Therapeutics for Multiple Sclerosis
    Heike Wulff; Fiscal Year: 2007
    ..Following up on anecdotal reports from the late 1980s that tea prepared from Ruta graveolens, the common rue, had beneficial effects in MS, we discovered that Ruta contained a small molecule called ..