cocculus

Summary

Summary: A plant genus of the family MENISPERMACEAE. Members contain sinococuline, coccuvine and other ALKALOIDS.

Top Publications

  1. ncbi Diuretic, laxative and toxicity studies of Cocculus hirsutus aerial parts
    S Ganapaty
    Department of Pharmaceutical Sciences, Andhra University, Visakhapatnam, A P 530003, India
    Fitoterapia 73:28-31. 2002
  2. doi Simultaneous determination of structurally diverse compounds in different Fangchi species by UHPLC-DAD and UHPLC-ESI-MS/MS
    Hee Jung Sim
    College of Pharmacy, Kyung Hee University, Hoegi dong, Dongdaemoon gu, Seoul 130 701, Korea
    Molecules 18:5235-50. 2013
  3. ncbi Inhibition of the bacterial surface protein anchoring transpeptidase sortase by medicinal plants
    Soo Whan Kim
    Natural Products Research Institute, Seoul National University, 28 Yungun, Jongro, Seoul 110 460, Korea
    Biosci Biotechnol Biochem 66:2751-4. 2002
  4. doi Laboratory study on larvicidal activity of indigenous plant extracts against Anopheles subpictus and Culex tritaeniorhynchus
    G Elango
    PG and Research Department of Zoology, C Abdul Hakeem College, Vellore District, Tamil Nadu, India
    Parasitol Res 104:1381-8. 2009
  5. doi Acute and chronic diuretic effect of ethanolic extract of leaves of Cocculus hirsutus (L.) Diles in normal rats
    Sachin L Badole
    Department of Pharmacology, Poona College of Pharmacy, Bharati Vidyapeeth University, Erandwane, Pune, India
    J Pharm Pharmacol 61:387-93. 2009
  6. doi Bisbenzylisoquinoline alkaloids from Cocculus pendulus
    - Atta-Ur-Rahman
    H E J Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan
    Nat Prod Res 23:1265-73. 2009
  7. doi Oviposition-deterrent, ovicidal, and repellent activities of indigenous plant extracts against Anopheles subpictus Grassi (Diptera: Culicidae)
    G Elango
    Unit of Bioactive Natural Products, P G and Research Department of Zoology, C Abdul Hakeem College, Melvisharam, 632 509, Tamil Nadu, India
    Parasitol Res 105:1567-76. 2009
  8. doi Evaluation of the phototoxic potential of plants used in oriental medicine
    Ki Min Bark
    Department of Chemical Education and Research Institute of Life Science, Gyeongsang National University, Jinju, 660 701, South Korea
    J Ethnopharmacol 127:11-8. 2010
  9. doi Efficacy of botanical extracts against Japanese encephalitis vector, Culex tritaeniorhynchus
    Gandhi Elango
    Unit of Bioactive Natural Products, Post Graduate and Research Department of Zoology, C Abdul Hakeem College, Melvisharam, 632509 Vellore District, Tamil Nadu, India
    Parasitol Res 106:481-92. 2010
  10. doi Studies on effects of indigenous plant extracts on filarial vector Culex tritaeniorhynchus Giles
    G Elango
    Unit of Bioactive Natural Products, Post Graduate and Research Department of Zoology, C Abdul Hakeem College, Melvisharam, 632 509, Vellore District, Tamil Nadu, India
    Parasitol Res 107:167-76. 2010

Scientific Experts

  • J P Varshney
  • Tetsuo Gotoh
  • Kuei Meng Wu
  • Joseph E Jablonski
  • Attakorn Palasuwan
  • Fang Rong Chang
  • S Ganapaty
  • J Nortier
  • Claus F Claussen
  • Mohammad I Choudhary
  • Vaishali C Joshi
  • Surachai Nimgirawath
  • Gandhi Elango
  • G Elango
  • Abdul Abdul Rahuman
  • A Bagavan
  • C Kamaraj
  • A Abduz Zahir
  • A Abdul Rahuman
  • - Atta-Ur-Rahman
  • Abdul Abduz Zahir
  • Chinnaperumal Kamaraj
  • Asokan Bagavan
  • Hee Jung Sim
  • H Heinle
  • Ki Min Bark
  • Govindasamy Rajakumar
  • Sampath Marimuthu
  • Thirunavukkarasu Santhoshkumar
  • Sachin L Badole
  • Marco Lucertini
  • - Atia-tul-Wahab
  • Hua Zhang
  • Dali M Tsakadze
  • Soo Whan Kim
  • Ji Hee Kim
  • Jongki Hong
  • Kang Ro Lee
  • Chidambaram Jayaseelan
  • Eun Phil Heo
  • W M Kuebler
  • S Marimuthu
  • G Rajakumar
  • Man Bae Kim
  • Seong Tae Lee
  • C Tober
  • Eun Mee Gil
  • D Zhang
  • Ki Deuk Han
  • T Santhoshkumar
  • R Jaggi
  • Tae Heung Kim
  • Subhash L Bodhankar
  • S Zia Sultani
  • Subodh Bhardwaj
  • Naimesh M Patel
  • C Venkatesan
  • Sarfraz A Nawaz
  • Nadia Mirante
  • Pierandrea Trivelloni
  • Maria Casagrande
  • Vittoria Lugli
  • Jian Min Yue
  • Abdulatip Abdusamatov
  • Shota A Samsoniya
  • Richsivoi Ziaev
  • Iqbal M Choudhary
  • Sarfraz Ahmad Nawaz
  • Il Moo Chang
  • Ki Bong Oh

Detail Information

Publications29

  1. ncbi Diuretic, laxative and toxicity studies of Cocculus hirsutus aerial parts
    S Ganapaty
    Department of Pharmaceutical Sciences, Andhra University, Visakhapatnam, A P 530003, India
    Fitoterapia 73:28-31. 2002
    The aqueous extract of the Cocculus hirsutus aerial parts (100 and 200 mg/kg, p.o.) showed significant diuretic activity and laxative effect in rats. The acute toxicity, orally evaluated in mice, was found to be higher than 3000 mg/kg.
  2. doi Simultaneous determination of structurally diverse compounds in different Fangchi species by UHPLC-DAD and UHPLC-ESI-MS/MS
    Hee Jung Sim
    College of Pharmacy, Kyung Hee University, Hoegi dong, Dongdaemoon gu, Seoul 130 701, Korea
    Molecules 18:5235-50. 2013
    ..the quality control of Fangchi species of different origins, including Sinomenium acutum, Stephania tetrandra, Cocculus trilobus and Aristolochia fangchi...
  3. ncbi Inhibition of the bacterial surface protein anchoring transpeptidase sortase by medicinal plants
    Soo Whan Kim
    Natural Products Research Institute, Seoul National University, 28 Yungun, Jongro, Seoul 110 460, Korea
    Biosci Biotechnol Biochem 66:2751-4. 2002
    ..Among 80 medicinal plants tested, Cocculus trilobus, Fritillaria verticillata, Liriope platyphylla, and Rhus verniciflua had strong inhibitory activity...
  4. doi Laboratory study on larvicidal activity of indigenous plant extracts against Anopheles subpictus and Culex tritaeniorhynchus
    G Elango
    PG and Research Department of Zoology, C Abdul Hakeem College, Vellore District, Tamil Nadu, India
    Parasitol Res 104:1381-8. 2009
    ..Correa ex Roxb, Andrographis lineata Wallich ex Nees., Andrographis paniculata (Burm.f.) Wall. ex Nees., Cocculus hirsutus (L.) Diels, Eclipta prostrata L., and Tagetes erecta L...
  5. doi Acute and chronic diuretic effect of ethanolic extract of leaves of Cocculus hirsutus (L.) Diles in normal rats
    Sachin L Badole
    Department of Pharmacology, Poona College of Pharmacy, Bharati Vidyapeeth University, Erandwane, Pune, India
    J Pharm Pharmacol 61:387-93. 2009
    The objective of this study was to evaluate the acute and chronic diuretic effect of the ethanolic extract of the leaves of Cocculus hirsutus (L.) Diles.
  6. doi Bisbenzylisoquinoline alkaloids from Cocculus pendulus
    - Atta-Ur-Rahman
    H E J Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan
    Nat Prod Res 23:1265-73. 2009
    ..1), and four known bisbenzylisoquinoline alkaloids 2-5, along with a morphinan alkaloid 6 were isolated from Cocculus pendulus. The structures for these compounds were deduced by spectroscopic methods...
  7. doi Oviposition-deterrent, ovicidal, and repellent activities of indigenous plant extracts against Anopheles subpictus Grassi (Diptera: Culicidae)
    G Elango
    Unit of Bioactive Natural Products, P G and Research Department of Zoology, C Abdul Hakeem College, Melvisharam, 632 509, Tamil Nadu, India
    Parasitol Res 105:1567-76. 2009
    ..Correa ex Roxb, Andrographis lineata Wallich ex Nees, and Cocculus hirsutus (L...
  8. doi Evaluation of the phototoxic potential of plants used in oriental medicine
    Ki Min Bark
    Department of Chemical Education and Research Institute of Life Science, Gyeongsang National University, Jinju, 660 701, South Korea
    J Ethnopharmacol 127:11-8. 2010
    ..Phototoxicity can be either harmful or beneficial. Yet the phototoxicity of oriental medicinal plants is an understudied area. The purpose of this study is to fill in this gap...
  9. doi Efficacy of botanical extracts against Japanese encephalitis vector, Culex tritaeniorhynchus
    Gandhi Elango
    Unit of Bioactive Natural Products, Post Graduate and Research Department of Zoology, C Abdul Hakeem College, Melvisharam, 632509 Vellore District, Tamil Nadu, India
    Parasitol Res 106:481-92. 2010
    ..effect of leaf hexane and chloroform extracts of Aegle marmelos, Andrographis lineata, Andrographis paniculata, Cocculus hirsutus, Eclipta prostrata, and Tagetes erecta on repellent, ovicidal, and oviposition-deterrent activities ..
  10. doi Studies on effects of indigenous plant extracts on filarial vector Culex tritaeniorhynchus Giles
    G Elango
    Unit of Bioactive Natural Products, Post Graduate and Research Department of Zoology, C Abdul Hakeem College, Melvisharam, 632 509, Vellore District, Tamil Nadu, India
    Parasitol Res 107:167-76. 2010
    ..Acanthaceae), Andrographis paniculata (Burm.f.) Wall. ex Nees. (Acanthaceae), Cocculus hirsutus (L.) Diels (Menispermaceae), Eclipta prostrata L. (Asteraceae) and Tagetes erecta L...
  11. doi Evaluation of repellent properties of botanical extracts against Culex tritaeniorhynchus Giles (Diptera: Culicidae)
    Gandhi Elango
    Unit of Nanotechnology and Bioactive Natural Products, Post Graduate and Research Department of Zoology, C Abdul Hakeem College, Melvisharam, Vellore District, Tamil Nadu, India
    Parasitol Res 107:577-84. 2010
    ..Correa ex Roxb, Andrographis lineata Wallich ex Nees., Andrographis paniculata (Burm.f.) Wallich ex Nees., Cocculus hirsutus (L.) Diels, Eclipta prostrata L., and Tagetes erecta L...
  12. doi The low-dose combination preparation Vertigoheel activates cyclic nucleotide pathways and stimulates vasorelaxation
    H Heinle
    Institute of Physiology, University of Tuebingen, Tuebingen, Germany
    Clin Hemorheol Microcirc 46:23-35. 2010
    ..Vertigoheel and one of its constituents, Anamirta cocculus, stimulated adenylate cyclase activity, while another constituent, Conium maculatum, inhibited phosphodiesterase ..
  13. doi Evaluation of medicinal plant extracts against ticks and fluke
    Gandhi Elango
    Unit of Nanotechnology and Bioactive Natural Products, P G and Research Department of Zoology, C Abdul Hakeem College, Melvisharam, 632 509 Vellore District, Tamil Nadu, India
    Parasitol Res 108:513-9. 2011
    ..Correa ex Roxb, Andrographis lineata Wallich ex Nees., Andrographis paniculata (Burm.f.) Wallich ex Nees., Cocculus hirsutus (L.) Diels, Eclipta prostrata L., and Tagetes erecta L...
  14. ncbi Studies on effects of indigenous plant extracts on malarial vector, Anopheles subpictus Grassi (Diptera:Culicidae)
    G Elango
    Unit of Bioactive Natural Products, Post Graduate and Research Department of Zoology, C Abdul Hakeem College, Melvisharam 632 509, Vellore District, Tamil Nadu, India
    Trop Biomed 27:143-54. 2010
    ..of leaf hexane and chloroform extracts of Aegle marmelos, Andrographis lineata, Andrographis paniculata, Cocculus hirsutus, Eclipta prostrata and Tagetes erecta against Anopheles subpictus Grassi (Diptera:Culicidae)...
  15. doi Efficacy of medicinal plant extracts against malarial vector, Anopheles subpictus Grassi
    Gandhi Elango
    Unit of Nanotechnology and Bioactive Natural Products, Post Graduate and Research Department of Zoology, C Abdul Hakeem College, Melvisharam, 632 509, Vellore District, Tamil Nadu, India
    Parasitol Res 108:1437-45. 2011
    ..Correa ex Roxb, Andrographis lineata Wallich ex Nees., Andrographis paniculata (Burm.f.) Wall. ex Nees., Cocculus hirsutus L. Diels, Eclipta prostrata L., and Tagetes erecta L...
  16. doi Total synthesis and antimicrobial activity of +/--laurelliptinhexadecan-1-one and +/--laurelliptinoctadecan-1-one
    Surachai Nimgirawath
    Department of Chemistry, Faculty of Science, Silpakorn University, Nakorn Pathom, Thailand
    Molecules 13:2935-47. 2008
    ..previously assigned to (+)-laurelliptinhexadecan-1-one (1a) and (+)-laurelliptinoctadecan-1-one (1b) from Cocculus orbiculatus (L.) DC. (Menispermaceae) have been confirmed by total synthesis of the racemic alkaloids...
  17. doi Stability of picrotoxin during yogurt manufacture and storage
    J E Jablonski
    U S Food and Drug Administration FDA, Natl Center for Food Safety and Technology NCFST, 6502 S Archer Rd, Summit Argo, IL 60501, USA
    J Food Sci 73:T121-8. 2008
    Picrotoxin is a neurotoxin found in the berries of Anamirta cocculus, a plant native to Southeast Asia. Picrotoxin has potential for being used as a biological weapon since the toxin is relatively easy to isolate and purify...
  18. ncbi Renal interstitial fibrosis and urothelial carcinoma associated with the use of a Chinese herb (Aristolochia fangchi)
    J L Nortier
    Department of Nephrology, Erasme Hospital, Universite Libre de Bruxelles, 808 Route de Lennik, B 1070 Brussels, Belgium
    Toxicology 181:577-80. 2002
    ..are considered interchangeable with certain other herbal ingredients and are also sometimes mistaken for ST, Akebia, Asarum, Clematis spp. and Cocculus spp. in herbal remedies.
  19. ncbi New cholinesterase inhibiting bisbenzylisoquinoline alkaloids from Cocculus pendulus
    - Atta-Ur-Rahman
    H E J Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Pakistan
    Chem Pharm Bull (Tokyo) 52:802-6. 2004
    Phytochemical investigation on Cocculus pendulus (J. R. & G. FORST.) resulted in the isolation of two new and three known bisbenzylisoquinoline alkaloids...
  20. ncbi Alkaloid and phenolic compounds of Galanthus caucasicus, Magnolia obovata, Cocculus laurifolius, and Veratrum lobelianum grown in Georgia
    Dali M Tsakadze
    Department of Chemistry, Iv Javakhishvili Tbilisi State University, Chavchavadze, Tbilisi, GA, USA
    Mol Divers 9:41-4. 2005
    A collection of plants from the country of Georgia (Galanthus caucasicus, Magnolia obovata, Cocculus laurifolius, and Veratrum lobelianum) has been studied for their alkaloid content...
  21. ncbi New bisbenzylisoquinolines, fatty acid amidic aporphines, and a protoberberine from Formosan Cocculus orbiculatus
    Fang Rong Chang
    Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan, Republic of China
    J Nat Prod 68:1056-60. 2005
    ..one new protoberberine (-)-4-methoxy-13,14-dihydrooxypalmatine (8) have been isolated from the stems of Taiwanese Cocculus orbiculatus...
  22. ncbi Inhibition of Heinz body induction in an in vitro model and total antioxidant activity of medicinal Thai plants
    Attakorn Palasuwan
    Department of Clinical Microscopy, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand
    Asian Pac J Cancer Prev 6:458-63. 2005
    ..extracts from Terminalia citrina, Cassia timoriensis, and Derris elliptica were the highest followed by Anamirta cocculus, and Oroxylum indicum respectively...
  23. ncbi Does the number of diapausing eggs laid on bark affect the population dynamics of the spider mite Panonychus mori?
    Tetsuo Gotoh
    Laboratory of Applied Entomology and Zoology, Faculty of Agriculture, Ibaraki University, Ami, Ibaraki 300 0393, Japan
    Exp Appl Acarol 39:75-83. 2006
    ..Panonychus mori showed a single population density peak on its host plant moonseed, Cocculus trilobus...
  24. ncbi New bisbenzylisoquinoline alkaloids from Cocculus laurifolius
    Hua Zhang
    State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, P R China
    Nat Prod Res 20:553-7. 2006
    ..alpha, alpha'-dioxo-7'-O-demethylstebisimine (1) and 7'-O-demethylstebisimine (2), along with 14 known alkaloids, were isolated from the roots of Cocculus laurifolius. These alkaloids were characterized mainly by spectroscopic methods.
  25. ncbi Complexities of the herbal nomenclature system in traditional Chinese medicine (TCM): lessons learned from the misuse of Aristolochia-related species and the importance of the pharmaceutical name during botanical drug product development
    K M Wu
    Center for Drug Evaluation and Research, FDA, 10903 New Hampshire Avenue, Silver Spring, MD 20993, USA
    Phytomedicine 14:273-9. 2007
    ..to multiple species): the herb fangji refers to the root of either Aristolochia fangchi, Stephania tetrandra or Cocculus trilobus; in this case, the first belongs to a different family (Aristolochiaceae) than the latter two (..
  26. ncbi Clinical management of idiopathic epilepsy in dogs with homeopathic Belladonna 200C: a case series
    J P Varshney
    Division of Medicine, Indian Veterinary Research Institute, Izatnagar, India
    Homeopathy 96:46-8. 2007
    ..Four dogs with head shaking syndrome in addition to seizures were given Cocculus 6C, 3-4 drops orally weekly for 3 months in addition...
  27. ncbi The effect of cinnarizine and cocculus indicus on simulator sickness
    Marco Lucertini
    Aeronautica Militare Centro Sperimentale di Volo Reparto Medicina Aeronautica e Spaziale, Pomezia Roma, Italy
    Physiol Behav 91:180-90. 2007
    ..to an experimental design based on a double-blind, balanced administration of either 30 mg cinnarizine (CIN), or Cocculus Indicus 6CH (COC), or placebo (PLC) before one trial of about one hour spent inside a spatial disorientation ..
  28. ncbi The slow-brainstem syndrome: tinnitus and dyssynchrony in the central nervous system
    Claus F Claussen
    Neurootological 4 G Forschung Research Institute, Bad Kissingen, Germany
    Int Tinnitus J 13:105-9. 2007
    ..By evaluating therapeutic responses, we noted especially in this group that a combination of cocculus (picrotoxin), conium (Coniine), amber, and petroleum (Vertigoheel) has a "tune-up" effect on the brainstem...
  29. doi Authentication of Stephania tetrandra S. Moore (Fang Ji) and differentiation of its common adulterants using microscopy and HPLC analysis
    Vaishali C Joshi
    National Center for Natural Products Research, Research Institute of Pharmaceutical Science, School of Pharmacy, University of Mississippi, P O Box 1848, University, MS 38677, USA
    J Nat Med 62:117-21. 2008
    ..C. Wu ex L. D. Chow and S. M. Hwang, Cocculus orbiculatus (L.) DC., Stephania tetrandra S. Moore, and Sinomenium acutum Rehder and E. H. Wilson...