ferula

Summary

Summary: A plant genus of the family APIACEAE. It contains pungent oils and resins. It is used to flavor curries, as a carminative, and as cat and dog repellent. The occasionally used common name of 'giant fennel' should not be confused with true fennel (FOENICULUM).

Top Publications

  1. ncbi Asafoetida inhibits early events of carcinogenesis: a chemopreventive study
    M Saleem
    Department of Medical Elementology and Toxicology, Faculty of Science, Jamia Hamdard (Hamdard University, New Delhi, India
    Life Sci 68:1913-21. 2001
  2. ncbi Evaluation of the anticonvulsant activity of the seed acetone extract of Ferula gummosa Boiss. against seizures induced by pentylenetetrazole and electroconvulsive shock in mice
    Mohammad Sayyah
    Department of Physiology and Pharmacology, Institute Pasteur of Iran, Tehran, Iran
    J Ethnopharmacol 82:105-9. 2002
  3. ncbi An unusual sesquiterpene derivative from Ferula kuhistanica
    Kimiko Tamemoto
    Faculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1 78, Japan
    J Nat Prod 65:1323-4. 2002
  4. ncbi Sesquiterpenes from Ferula penninervis
    Yasuhiro Shikishima
    Faculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1 78, Tokushima 770 8505, Japan
    J Nat Prod 65:1897-903. 2002
  5. ncbi Sesquiterpene coumarins from Ferula fukanensis and nitric oxide production inhibitory effects
    Tsunetake Motai
    College of Pharmacy, Nihon University, 7 7 1 Narashinodai, Funabashi, Chiba 274 8555, Japan
    J Nat Prod 67:432-6. 2004
  6. ncbi Traditional uses, phytochemistry and pharmacology of asafoetida (Ferula assa-foetida oleo-gum-resin)-a review
    Milad Iranshahy
    Biotechnology Research Center and School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
    J Ethnopharmacol 134:1-10. 2011
  7. ncbi Ferulsinaic acid, a sesquiterpene coumarin with a rare carbon skeleton from Ferula species
    Ahmed A Ahmed
    Department of Chemistry, El Minia University, El Minia 61519, Egypt
    Phytochemistry 68:680-6. 2007
  8. ncbi Two matrix metalloproteinases inhibitors from Ferula persica var. persica
    A R Shahverdi
    Department of Pharmaceutical Biotechnology and Medicinal Plant Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
    Phytomedicine 13:712-7. 2006
  9. ncbi Chemomodulatory influence of Ferula asafoetida on mammary epithelial differentiation, hepatic drug metabolizing enzymes, antioxidant profiles and N-methyl-N-nitrosourea-induced mammary carcinogenesis in rats
    G U Mallikarjuna
    Cancer Biology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India
    Breast Cancer Res Treat 81:1-10. 2003
  10. ncbi Effects of Ferula gummosa Boiss. fractions on morphine dependence in mice
    M Ramezani
    Department of Pharmacognosy and Biotechnology, School of Pharmacy, Mashhad University of Medical Sciences, P O Box 91775 1365, Mashhad, Iran
    J Ethnopharmacol 77:71-5. 2001

Scientific Experts

Detail Information

Publications149 found, 100 shown here

  1. ncbi Asafoetida inhibits early events of carcinogenesis: a chemopreventive study
    M Saleem
    Department of Medical Elementology and Toxicology, Faculty of Science, Jamia Hamdard (Hamdard University, New Delhi, India
    Life Sci 68:1913-21. 2001
    b>Ferula (a genus of many species) commonly known as asafoetida is used as a flavoring agent in food and is used as a traditional medicine for many diseases in many parts of world...
  2. ncbi Evaluation of the anticonvulsant activity of the seed acetone extract of Ferula gummosa Boiss. against seizures induced by pentylenetetrazole and electroconvulsive shock in mice
    Mohammad Sayyah
    Department of Physiology and Pharmacology, Institute Pasteur of Iran, Tehran, Iran
    J Ethnopharmacol 82:105-9. 2002
    b>Ferula gummosa Boiss. (Apiaceae) which has been used as an antiepileptic remedy in Iranian traditional medicine was evaluated for anticonvulsant activity against experimental seizures. The seed acetone extract of F...
  3. ncbi An unusual sesquiterpene derivative from Ferula kuhistanica
    Kimiko Tamemoto
    Faculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1 78, Japan
    J Nat Prod 65:1323-4. 2002
    ..new sesquiterpene derivative, kuhistaferone (1), was isolated from the fruits of the Uzbekistan medicinal plant Ferula kuhistanica. The structure of 1 was established on the basis of spectroscopic evidence...
  4. ncbi Sesquiterpenes from Ferula penninervis
    Yasuhiro Shikishima
    Faculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1 78, Tokushima 770 8505, Japan
    J Nat Prod 65:1897-903. 2002
    The ethyl acetate soluble extract of the dried roots of Ferula penninervis gave 17 new sesquiterpenes [15 of the guaiane-type, ferupennins A-O (1-15), and two of the eudesmane-type, 1alpha-hydroxy-2-oxo-5alpha,7beta,11betaH-eudesm-3-en-..
  5. ncbi Sesquiterpene coumarins from Ferula fukanensis and nitric oxide production inhibitory effects
    Tsunetake Motai
    College of Pharmacy, Nihon University, 7 7 1 Narashinodai, Funabashi, Chiba 274 8555, Japan
    J Nat Prod 67:432-6. 2004
    ..fukanefuromarin D (8), and fukanemarin A (9), were isolated from a 80% aqueous methanol extract of the roots of Ferula fukanensis...
  6. ncbi Traditional uses, phytochemistry and pharmacology of asafoetida (Ferula assa-foetida oleo-gum-resin)-a review
    Milad Iranshahy
    Biotechnology Research Center and School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
    J Ethnopharmacol 134:1-10. 2011
    The old traditional phytomedicine asafoetida, an oleo-gum-resin obtained from the roots of different Ferula assa-foetida, is used in different countries for various purposes...
  7. ncbi Ferulsinaic acid, a sesquiterpene coumarin with a rare carbon skeleton from Ferula species
    Ahmed A Ahmed
    Department of Chemistry, El Minia University, El Minia 61519, Egypt
    Phytochemistry 68:680-6. 2007
    Fractionation of methylene chloride extracts of the resin of Ferula vesceritensis and F. sinaica afforded three sesquiterpene coumarins and a glucose derivative. One of them was a sesquiterpene with a rare carbon skeleton...
  8. ncbi Two matrix metalloproteinases inhibitors from Ferula persica var. persica
    A R Shahverdi
    Department of Pharmaceutical Biotechnology and Medicinal Plant Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
    Phytomedicine 13:712-7. 2006
    ..Here we studied the chloroform extract of Ferula persica var. persica. The influence of these extracts vs...
  9. ncbi Chemomodulatory influence of Ferula asafoetida on mammary epithelial differentiation, hepatic drug metabolizing enzymes, antioxidant profiles and N-methyl-N-nitrosourea-induced mammary carcinogenesis in rats
    G U Mallikarjuna
    Cancer Biology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India
    Breast Cancer Res Treat 81:1-10. 2003
    The present study was conducted to ascertain the modulatory influences of Ferula asafoetida L...
  10. ncbi Effects of Ferula gummosa Boiss. fractions on morphine dependence in mice
    M Ramezani
    Department of Pharmacognosy and Biotechnology, School of Pharmacy, Mashhad University of Medical Sciences, P O Box 91775 1365, Mashhad, Iran
    J Ethnopharmacol 77:71-5. 2001
    Activity-guided fractionation of methanol-chloroform (1:1) extract of Ferula gummosa was carried out to investigate the isolation of the active component(s) responsible for the alleviation of morphine withdrawal syndrome induced by ..
  11. ncbi Galbanic acid isolated from Ferula assafoetida exerts in vivo anti-tumor activity in association with anti-angiogenesis and anti-proliferation
    Kwan Hyun Kim
    College of Oriental Medicine, Kyung Hee University, 1 Hoegi dong, Dongdaemun Gu, Seoul 130 701, Republic of Korea
    Pharm Res 28:597-609. 2011
    ..To investigate whether galbanic acid (GBA) exerts anti-angiogenic and anti-cancer activities...
  12. ncbi Biologically active sesquiterpene coumarins from Ferula species
    Zeinab Esmail Nazari
    Biotechnology Research Center and School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
    Phytother Res 25:315-23. 2011
    Extracts from different species of the genus Ferula (Apiaceae) have had various biomedical applications for many centuries...
  13. ncbi Sesquiterpene coumarins from Ferula gumosa
    Mehrdad Iranshahi
    Biotechnology Research Center and School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
    J Nat Prod 73:1958-62. 2010
    ..acantrifoside E and 4-hydroxybenzoic acid 4-(6-O-sulfo)glucopyranoside, were isolated from a methanolic extract of Ferula gumosa roots. The structures of 1-3 were elucidated by spectroscopic data interpretation...
  14. ncbi Polar secondary metabolites of Ferula persica roots
    Mehrdad Iranshahi
    Department of Pharmacognosy and Biotechnology, Biotechnology Research Center, Faculty of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
    Phytochemistry 69:473-8. 2008
    Phytochemical investigation of the methanolic extract of the dried roots of Ferula persica resulted in four sesquiterpene coumarin glycosides, persicaosides A-D, and two known phytosterol glucosides, sitosterol 3-O-beta-glucoside and ..
  15. ncbi Activity of single components of Ferula hermonis on male rat sexual behavior
    P Zanoli
    Department of Pharmaceutical Sciences and National InterUniversity Consortium for the Study of Natural Active Principles CINSPAN, University of Modena and Reggio Emilia, Modena, Italy
    Int J Impot Res 17:513-8. 2005
    The influence of the single components of Ferula hermonis extract on sexual behavior was studied in male rats. Sexually potent and sluggish/impotent animals were orally treated acutely (2.5 mg/kg) and subchronically (0...
  16. ncbi Antiproliferative effects of daucane esters from Ferula communis and F. arrigonii on human colon cancer cell lines
    F Poli
    Department of Evolutionary and Experimental Biology, University of Bologna, Italy
    Phytother Res 19:152-7. 2005
    Certain jaesekanadiol p-hydroxy- and p-methoxybenzoates - typical of Ferula communis and Ferula arrigonii sardinian plants - show antiproliferative activity on human colon cancer less...
  17. ncbi New sesquiterpenes from Ferula ferulaeoides (Steud.) Korovin. VI. Isolation and identification of three new dihydrofuro[2,3-b]chromones
    Akito Nagatsu
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan
    Chem Pharm Bull (Tokyo) 50:675-7. 2002
    ..were isolated from the roots of Ferula ferulaeoides. The structures were established by comprehensive spectral analysis...
  18. ncbi Sesquiterpene coumarins from Ferula szowitsiana and in vitro antileishmanial activity of 7-prenyloxycoumarins against promastigotes
    Mehrdad Iranshahi
    Department of Pharmacognosy and Biotechnology, Faculty of Pharmacy, Mashhad, Iran
    Phytochemistry 68:554-61. 2007
    ..B (8), farnesiferol C (9), persicasulfide A (10), beta-sitosterol and stigmasterol were isolated from the roots of Ferula szowitsiana...
  19. ncbi Diversolides A-G, guaianolides from the roots of Ferula diversivittata
    Mehrdad Iranshahi
    Department of Pharmacognosy and Biotechnology, Biotechnology Research Center, Faculty of Pharmacy, Mashhad University of Medical Sciences, Vakilabad Boulevard, Mashhad, Iran
    Phytochemistry 69:2753-7. 2008
    ..A-G (1-7), together with two known compounds, diversin (8) and stigmasterol, were isolated from the roots of Ferula diversivittata...
  20. ncbi Anti-diabetic activity of Ferula assafoetida extract in normal and alloxan-induced diabetic rats
    Ahmed Saber Abu-Zaiton
    Department of Biological Sciences, Al Hussein Bin Talal University, P O Box 20, Ma an, Jordan
    Pak J Biol Sci 13:97-100. 2010
    ....
  21. ncbi Farnesiferol A from Ferula persica and galbanic acid from Ferula szowitsiana inhibit P-glycoprotein-mediated rhodamine efflux in breast cancer cell lines
    Mohammad Yahya Hanafi-Bojd
    Biotechnology Research Center and School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
    Planta Med 77:1590-3. 2011
    ..In the current study, we investigated the effects of galbanic acid (from the roots of Ferula szowitsiana) and farnesiferol A (from the roots of Ferula persica) on functionality of the drug transporter P-..
  22. ncbi Sesquiterpenes from aerial parts of Ferula vesceritensis
    Karima Oughlissi-Dehak
    Universite de Lyon, UMR 5557 CNRS, Département de Pharmacognosie, Botanique et Phytothérapie, Faculte de Pharmacie, 8 avenue Rockefeller, 69373 Lyon Cedex 08, France
    Phytochemistry 69:1933-8. 2008
    From the dichloromethane extract of aerial parts of Ferula vesceritensis (Apiaceae), 11 sesquiterpene derivatives were isolated...
  23. ncbi Cancer chemopreventive activity of terpenoid coumarins from Ferula species
    Mehrdad Iranshahi
    Department of Pharmacognosy and Biotechnology, Biotechnology Research Center, Faculty of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
    Planta Med 74:147-50. 2008
    ..In the present study, we carried out a primary screening of ten terpenoid coumarins isolated from plants of the Ferula species, examining their possible inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation ..
  24. ncbi Conferone from Ferula schtschurowskiana enhances vinblastine cytotoxicity in MDCK-MDR1 cells by competitively inhibiting P-glycoprotein transport
    Chantal Barthomeuf
    UMR INSERM U 484, Universite d Auvergne, Centre hospitalier J Perrin, Laboratoire de Pharmacognosie et de Biotechnologie, Faculte de Pharmacie, Clermont Ferrand, France
    Planta Med 72:634-9. 2006
    ..The present study shows that conferone, a sesquiterpene coumarin ether isolated for the first time from Ferula schtschurowskiana, endemic in Uzbekistan, enhances the cell toxicity of vinblastine (VBL) in MDR1-transfected ..
  25. ncbi New sesquiterpene coumarins from the roots of Ferula flabelliloba
    Mehrdad Iranshahi
    Department of Pharmacognosy, Biotechnology Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
    Pharm Biol 48:217-20. 2010
    ..A, conferdione, umbelliprenin, conferone, feselol, lehmferin and farnesiferol B were isolated from the roots of Ferula flabelliloba Rech. f. & Aell. (Apiaceae)...
  26. ncbi Spasmolytic activity of essential oil and various extracts of Ferula gummosa Boiss. on ileum contractions
    H Sadraei
    Department of Pharmacology, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Iran
    Phytomedicine 8:370-6. 2001
    Traditional herbal medicines such as Ferula gummosa Boiss. have been used for treatment of intestinal disorders in Iran. To date no pharmacological evidence for their effectiveness has been reported...
  27. ncbi Ferula harmonis 'zallouh' and enhancing erectile function in rats: efficacy and toxicity study
    T S El-Thaher
    ARAGEN Biotechnology, Naor, Jordan
    Int J Impot Res 13:247-51. 2001
    b>Ferula harmonis, which is locally called 'zallouh' in the Middle East, is used as an aphrodisiac as it is reputed to enhance male sexual behavior, however, there is no scientific verification...
  28. ncbi Antimycobacterial constituents from Juniperus procera, Ferula communis and Plumbago zeylanica and their in vitro synergistic activity with isonicotinic acid hydrazide
    Jaber S Mossa
    Department of Pharmacognosy, College of Pharmacy, King Saud University, P O Box 2457, Riyadh 11451, Saudi Arabia
    Phytother Res 18:934-7. 2004
    ..procera. The MIC values of totarol, ferulenol (from Ferula communis) and plumbagin (from Plumbago zeylanica) were thus lowered from 1.25-2.5 to 0.15-0...
  29. ncbi Antispasmodic and hypotensive effects of Ferula asafoetida gum extract
    Mohammad Fatehi
    Department of Physiology and Pharmacology, Faculty of Medicine, Mashhad University of Medical Sciences, P O Box 91775 1843, Mashhad, Iran
    J Ethnopharmacol 91:321-4. 2004
    The effects of Ferula asafoetida gum extract on the contractile responses of the isolated guinea-pig ileum induced by acetylcholine, histamine and KCl, and on the mean arterial blood pressure of rat were investigated...
  30. ncbi Molluscicidal activity of Ferula asafoetida, Syzygium aromaticum and Carum carvi and their active components against the snail Lymnaea acuminata
    Pradeep Kumar
    Department of Zoology, DDU Gorakhpur University, Gorakhpur, UP 273 009, India
    Chemosphere 63:1568-74. 2006
    The molluscicidal activity of dried root latex powder of Ferula asafoetida, flower-bud powder of Syzygium aromaticum and seed powder of Carum carvi against the snail Lymnaea acuminata was studied...
  31. ncbi Molecular modelling and QSAR analysis of the estrogenic activity of terpenoids isolated from Ferula plants
    B F Rasulev
    Computational Center for Molecular Structure and Interactions, Jackson State University, 1235 J R Lynch Street, Jackson, MS 39217 0510, USA
    SAR QSAR Environ Res 18:663-73. 2007
    ..estrogenic activity in a series of terpenoid esters with aromatic and aliphatic acid substituents isolated from Ferula plants, was studied...
  32. ncbi Galbanic acid from Ferula szowitsiana enhanced the antibacterial activity of penicillin G and cephalexin against Staphylococcus aureus
    Ahmad Reza Shahverdi
    Department of Pharmaceutical Biotechnology and Medicinal Plant Research Center, Faculty of Pharmacy, Medical Sciences University of Tehran, Tehran 1417614411, Iran
    Biol Pharm Bull 30:1805-7. 2007
    In this study the enhancement effect of Ferula szowitsiana roots' acetone extract on the antibacterial activity of penicillin G and cephalexin was evaluated against Staphylococcus aureus...
  33. ncbi Umbelliprenin from Ferula szowitsiana inhibits the growth of human M4Beu metastatic pigmented malignant melanoma cells through cell-cycle arrest in G1 and induction of caspase-dependent apoptosis
    Chantal Barthomeuf
    University Clermont1, Laboratoire de Pharmacognosie Biotechnologies, INSERM, U484, Groupe de Recherche Clinique, UFR Pharmacie, Clermont Fd F 63001, France
    Phytomedicine 15:103-11. 2008
    ..the resazurin reduction test and FACS analysis to assess the cytostatic and cytotoxic effect of umbelliprenin from Ferula szowitsiana (Apiaceae) on human solid cancer cells and human primary fibroblasts...
  34. ncbi Auraptene from Ferula szowitsiana protects human peripheral lymphocytes against oxidative stress
    Fatemeh Soltani
    Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
    Phytother Res 24:85-9. 2010
    ..This study suggests that the antigenotoxic property of auraptene is of great pharmacological importance and might be beneficial for cancer prevention...
  35. ncbi Chemical composition and antimicrobial activity of the essential oil from Ferula glauca L. (F. communis L. subsp. glauca) growing in Marche (central Italy)
    Filippo Maggi
    Department of Environmental Sciences, Section of Botany and Ecology, University of Camerino, Via Pontoni 5, I 62032 Camerino, Italy
    Fitoterapia 80:68-72. 2009
    The essential oil obtained from different parts of Ferula glauca L. (formerly considered as a subspecies of F. communis) growing in Marche (central Italy), was analyzed for the first time by GC-FID and GC-MS...
  36. ncbi Sesquiterpenoids from the fruits of Ferula kuhistanica and antibacterial activity of the constituents of F. kuhistanica
    K Tamemoto
    Faculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, 770-8505, Tokushima, Japan
    Phytochemistry 58:763-7. 2001
    Ethyl acetate extracts of the air-dried fruits of Ferula kuhistanica afforded three daucane esters: kuhistanicaol H, I and J, together with nine other known compounds...
  37. ncbi Role of energy metabolism in the pregnancy interceptive action of Ferula assafoetida and Melia azedarach extracts in rat
    Govind Keshri
    Division of Endocrinology, Central Drug Research Institute, P O Box 173 Mahatma Gandhi Marg, Lucknow 226001, India
    Contraception 70:429-32. 2004
    Ethanolic extract of Ferula assafoetida and chloroform fraction of Melia azedarach, both devoid of estrogenic activity, were examined for their pregnancy interceptive property...
  38. ncbi Protective effects of selected medicinal plants against protein degradation, lipid peroxidation and deformability loss of oxidatively stressed human erythrocytes
    S M Suboh
    Department of Biological Sciences, University of Jordan, Amman, Jordan
    Phytother Res 18:280-4. 2004
    The effects of seven medicinal plants including Artemisia herba-alba, Ferula hermonis, Hibiscus sabdariffa, Nigella sativa, Teucrium polium, Trigonella foenum-graecum, and Allium sativum on protein degradation, lipid peroxidation, ..
  39. ncbi Sesquiterpene coumarins from Ferula fukanensis and nitric oxide production inhibitory effects
    Tsunetake Motai
    College of Pharmacy, Nihon University, Chiba, Japan
    Chem Pharm Bull (Tokyo) 52:1215-8. 2004
    ..fukanefuromarin F (3) and fukanefuromarin G (5) were isolated from a 80% aqueous methanol extract of the roots of Ferula fukanensis...
  40. ncbi Feruhermonins A-C: three daucane esters from the seeds of Ferula hermonis (Apiaceae)
    Abdurazag A Auzi
    Phytochemistry Research Laboratory, Department of Pharmaceutical Sciences, University of Strathclyde, Glasgow, UK
    J Asian Nat Prod Res 10:711-7. 2008
    Seventeen daucane esters have been isolated from the seeds of Ferula hermonis Boiss (Apiaceae)...
  41. ncbi Ferula hermonis impairs sexual behavior in hormone-primed female rats
    Paola Zanoli
    Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Italy
    Physiol Behav 86:69-74. 2005
    The influence of Ferula hermonis root extract on sexual behavior was studied in female rats...
  42. ncbi Novel antioxidants isolated from plants of the genera Ferula, Inula, Prangos and Rheum collected in Uzbekistan
    K Kogure
    Faculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1, 770 8505 Tokushima, Japan
    Phytomedicine 11:645-51. 2004
    We examined the effects of 48 compounds isolated from Ferula pallida, F. penninervis, Inula macrophylla, Prangos pabularia, P...
  43. ncbi Daucane phytoestrogens: a structure-activity study
    Giovanni Appendino
    Dipartimento di Scienze Chimiche, Alimentari, Farmaceutiche e Farmacologiche, Universita del Piemonte Orientale, Viale Ferrucci 33, 28100 Novara, Italy
    J Nat Prod 65:1612-5. 2002
    ..Homologation and vinylation were both detrimental for activity, as were methylation of the p-hydroxyl substituent and the introduction of oxygen functions on the adjacent carbons...
  44. ncbi The in vitro effect of Assafoetida on Trichomonas vaginalis
    Nashwa I Ramadan
    Department of Parasitology, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt
    J Egypt Soc Parasitol 33:615-30. 2003
    Assafoetida is an oleo-gum resin obtained from the roots and stems of many Ferula species such as F. foetida Regel, F. asafoetida Linn, F. alliacea Boiss. and F...
  45. ncbi Umbelliprenin from Ferula persica roots inhibits the red pigment production in Serratia marcescens
    Mehrdad Iranshahi
    Department of Pharmacognosy Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
    Z Naturforsch C 59:506-8. 2004
    The chloroform extract of Ferula persica var. persica roots was found to inhibit red pigment production of Serratia marcescens. A bioguided fractionation study by preparative thin layer chromatography (PTLC) detected a fraction (Rf = 0...
  46. ncbi A comparative study of Ferula hermonis root extracts and sildenafil on copulatory behaviour of male rats
    K A Hadidi
    Department of Pathology, Microbiology and Forensic Medicine, Faculty of Medicine, University of Jordan, Amman 11942, Jordan
    Fitoterapia 74:242-6. 2003
    The effect of 600 mg/kg given by oral route to rats of Ferula hermonis roots extracts (petroleum ether, ethyl acetate, methanol and water) was evaluated on sexual behaviour of male rats...
  47. ncbi Larvicidal activity of plant extracts used alone and in combination with known synthetic larvicidal agents against Aedes aegypti
    Gauri Harve
    Department of Zoonosis, Haffkine Institute, Mumbai 400012, India
    Indian J Exp Biol 42:1216-9. 2004
    Larvicidal activity of acetone and petroleum ether extracts of four plants Murraya koenigii, Coriandrum sativum, Ferula asafoetida, Trigonella foenum graceum and synthetic larvicides Fenthion and Temephos used alone and in combination was ..
  48. ncbi Ethnoveterinary practices for the treatment of parasitic diseases in livestock in Cholistan desert (Pakistan)
    Zahid Farooq
    Department of Zoology and Fisheries, University of Agriculture, Faisalabad 38040, Pakistan
    J Ethnopharmacol 118:213-9. 2008
    ..This study was conducted to document the ethnoveterinary medicinal (EVM) practices for the treatment of different parasitic diseases of livestock in Cholistan desert, Pakistan...
  49. pmc In vitro screening of tumoricidal properties of international medicinal herbs: part II
    Elizabeth A Mazzio
    College of Pharmacy and Pharmaceutical Sciences, Florida A and M University, Tallahassee, Florida 32307, USA
    Phytother Res 24:1813-24. 2010
    ..Erythrorhizon) Family (Boraginaceae) > beth root (Trillium Pendulum), Family (Liliaceae) and galbanum (Ferula Galbaniflua), Family (Apiaceae). Gromwell root is traditionally used in the preparation of Chinese medicinal tea...
  50. pmc Development and evaluation of hepatoprotective polyherbal formulation containing some indigenous medicinal plants
    P M Dandagi
    Department of Pharmaceutics, K L E S s College of Pharmacy, Belgaum 590 010, India
    Indian J Pharm Sci 70:265-8. 2008
    The present study explores the hepatoprotective activity of various extracts of Ferula asafoetida, Momordica charantia Linn and Nardostachys jatamansi against experimental hepatotoxicity...
  51. ncbi Studies on the in vitro and in vivo hypoglycemic activities of some medicinal plants used in treatment of diabetes in Jordanian traditional medicine
    I I Hamdan
    Department of Pharmaceutical Sciences, Faculty of Pharmacy, University of Jordan, Queen Rania Street, Amman, Jordan
    J Ethnopharmacol 93:117-21. 2004
    b>Ferula persica, Paronychia argentea, and Pistacia atlantica are three of the plants widely recommended by the herbalists and used for their hypoglycemic activity in Jordan...
  52. ncbi Evaluation of sedative and anticonvulsant activities of Unmadnashak Ghrita
    Girish S Achliya
    Department of Pharmaceutical Sciences, Nagpur University Campus, Amravati Road, 440033, India
    J Ethnopharmacol 94:77-83. 2004
    Unmadnashak Ghrita' (UG) is a ayurvedic formulation containing Ferula narthex (6 g), Gardenia gummifera (6 g), Ellataria cardamom (6 g), Bacopa monneri (6 g), and cow's ghee (clarified butter fat) (76 g)...
  53. ncbi Investigation on the phenolics of some spices having pharmacotherapeuthic properties
    U P Singh
    Department of Mycology and Plant Pathology, Institute of Agricultural Sciences, Banaras Hindu University, Varanasi 221005, India
    J Herb Pharmacother 4:27-42. 2004
    ..The spices are known to significantly contribute to the flavor, taste, and medicinal properties of food because of phenolics...
  54. ncbi [Silphium from Cyrenaica, an extinct medicinal plant]
    Charles Haas
    Académie nationale de médecine
    Bull Acad Natl Med 192:153-60. 2008
    ..The botanical identification of silphium is dificult, but the plant was an Umbellifera and most closely resembled Ferula tingitana...
  55. ncbi Synthesis and structure-activity relationships of novel warfarin derivatives
    Markus Gebauer
    Repatriation General Hospital, Pharmacy Department, Daws Rd, Daw Park, Adelaide, SA 5041, Australia
    Bioorg Med Chem 15:2414-20. 2007
    ..An example of a 4-hydroxycoumarin with an isoprenyl side chain is the natural product ferulenol 19 derived from Ferula communis. Ferulenol 19 confers approximately 22 times more potent inhibition than warfarin and is approximately 1...
  56. ncbi Ionophoretic properties of ferutinin
    M V Zamaraeva
    Department of Biophysics, Tashkent State University, Uzbekistan
    Cell Calcium 22:235-41. 1997
    The influence of the natural terpenoid ferutinin (4-oxy-6-(4-oxybenzoyloxy) dauc-8,9-en), isolated from the plant Ferula tenuisecta, on ion permeability of biological and artificial membranes was investigated...
  57. ncbi [Study on callus induction of Ferula sinkiangensis]
    Jun Zhu
    Xin Jiang Institute of Chinese Traditional Medical and Ethical Materia Medica, Urumqi 830002, China
    Zhong Yao Cai 32:1655-8. 2009
    To explore the effect of different culture conditions and hormone combinations on callus induction of Ferula sinkiangensis.
  58. ncbi Herbal compound farnesiferol C exerts antiangiogenic and antitumor activity and targets multiple aspects of VEGFR1 (Flt1) or VEGFR2 (Flk1) signaling cascades
    Jae Ho Lee
    Cancer Preventive Material Development ResearchCenter, College of Oriental Medicine, Kyunghee University, Seoul, Korea
    Mol Cancer Ther 9:389-99. 2010
    Farnesiferol C (FC) is one of the major compounds isolated from Ferula assafoetida, an Asian herbal spice used for cancer treatment as a folk remedy...
  59. ncbi Galbanic acid, a cytotoxic sesquiterpene from the gum resin of Ferula asafoetida, blocks protein farnesyltransferase
    Mi Ran Cha
    Korea Research Institute of Chemical Technology, Daejeon, Korea
    Planta Med 77:52-4. 2011
    ..Bioassay-guided purification of Ferula asafoetida (Umbelliferae) extract led to the isolation of the coumarin-derived sesquiterpene galbanic acid (1) as ..
  60. ncbi Cancer chemopreventive activity of diversin from Ferula diversivittata in vitro and in vivo
    M Iranshahi
    Department of Pharmacognosy, Biotechnology Research Center, School of Pharmacy, Mashhad University of Medical Sciences, MUMS, P O Box 91775 1365, Mashhad, Iran
    Phytomedicine 17:269-73. 2010
    ..1) together with four new sesquiterpene lactones (diversolides A, D, F and G, 2-5) isolated from the roots of Ferula diversivittata were studied for their possible inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) ..
  61. ncbi Characterization of anti-coagulant properties of prenylated coumarin ferulenol
    Monia Monti
    Dipartimento di Biochimica e Biologia Molecolare, Universita di Ferrara, Italy
    Biochim Biophys Acta 1770:1437-40. 2007
    We investigated the mechanisms underlying severe bleeding occurring upon consumption of Ferula communis...
  62. ncbi The genetic diversity and spatial genetic structure of the Corso-Sardinian endemic Ferula arrigonii Bocchieri (Apiaceae)
    C A Dettori
    Dipartimento di Scienze della Vita e dell Ambiente, Centro Conservazione Biodiversità CCB, Universita degli Studi di Cagliari, Cagliari, Italy
    Plant Biol (Stuttg) 16:1005-13. 2014
    ..In this work, the first assessment is reported of the species-wide spatial genetic structure and diversity of Ferula arrigonii Bocchieri, a Corso-Sardinian endemic located in a few coastal sites and on small islands...
  63. ncbi Influence of ferutinin on bone metabolism in ovariectomized rats. I: role in preventing osteoporosis
    Carla Palumbo
    Section of Human Anatomy, Department of Anatomy and Histology, University of Modena and Reggio Emilia, Via del Pozzo 71 Area policlinico, 41100, Modena, Italy
    J Bone Miner Metab 27:538-45. 2009
    ..The aim of the present study was to investigate the influence of Ferutinin, a phytoestrogen found in the plants of Ferula genus, on bone loss in ovariectomized rats...
  64. ncbi Genetic polymorphism and taxonomic infrastructure of the Pleurotus eryngii species-complex as determined by RAPD analysis, isozyme profiles and ecomorphological characters
    G I Zervakis
    National Agricultural Research Foundation, Institute of Kalamata, Lakonikis 85, 24100 Kalamata, Greece
    Microbiology 147:3183-94. 2001
    ..b>Ferula communis, Cachrys ferulacea, Thapsia garganica and Elaeoselinum asclepium subsp...
  65. ncbi Ferutinin induces in vitro eryptosis/erythroptosis in human erythrocytes through membrane permeabilization and calcium influx
    Minghui Gao
    Programme of Biochemistry, School of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong
    Chem Res Toxicol 26:1218-28. 2013
    Ferutinin, isolated from the root of Ferula hermonis and proposed to be used as an antiosteoporosis phytoestrogen, has death promoting activities in a number of cancer cells...
  66. ncbi Chloroform extract of underground parts of Ferula heuffelii: secondary metabolites and spasmolytic activity
    Ivan Pavlovic
    University of Belgrade Faculty of Pharmacy, Department of Pharmacognosy, Vojvode Stepe 450, RS 11221 Belgrade, phone 381 11 3951322 fax 381 11 3972840
    Chem Biodivers 11:1417-27. 2014
    Plants from the genus Ferula L. (Apiaceae) were used for various purposes in traditional medicine of different nations throughout the history. Ferula heuffelii Griseb. ex Heuffel is a perennial species endemic for Balkan peninsula...
  67. ncbi Influenza A (H(1)N(1)) Antiviral and Cytotoxic Agents from Ferula assa-foetida
    Chia Lin Lee
    Graduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan, Republic of China
    J Nat Prod 72:1568-72. 2009
    ..acid (3), along with 27 known compounds, were isolated from a CHCl(3)-soluble extract of Ferula assa-foetida through bioassay-guided fractionation...
  68. pmc Effect of asafoetida extract on growth and quality of Pleurotus ferulic
    Zuoshan Feng
    China Agricultural University, Beijing, China
    Int J Mol Sci 11:41-51. 2009
    ..Asafoetida extract influenced the volatile components of Pleurotus ferulic greatly, making the volatile components of cultivated pleurotus more similar to those of wild pleurotus (WP)...
  69. ncbi Bioactive sesquiterpene coumarins from Ferula pseudalliacea
    Dara Dastan
    Department of Phytochemistry, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, G C Evin, Tehran, Iran
    Planta Med 80:1118-23. 2014
    One new and five known sesquiterpene coumarins were isolated from the roots of Ferula pseudalliacea...
  70. ncbi Chemistry of spices: bornyl 4-methoxybenzoate from Ferula ovina (Boiss.) Boiss. (Apiaceae) induces hyperalgesia in mice
    Niko S Radulović
    Department of Chemistry, Faculty of Science and Mathematics, University of Nis, Visegradska 33, RS 18000 Nis, Serbia
    Food Funct 4:1751-8. 2013
    b>Ferula ovina (Boiss.) Boiss. is a traditional Iranian flavoring agent used as an ingredient of spices and condiments.
  71. ncbi The efficacy of essential oils as natural preservatives in vegetable oil
    Mohaddese Mahboubi
    1Microbiology Department, Barij Essence Medicinal Plants Research Center, Kashan, Iran
    J Diet Suppl 11:334-46. 2014
    ..The preservative efficacy of Daucus carota, Ferula gummosa, Eugenium caryophyllata, Oliveria decumbens, Pelargonium graveolens, Ziziphora tenuir, Acorus calamus, and ..
  72. ncbi Conservation genetics of the endangered Iberian steppe plant Ferula loscosii (Apiaceae)
    E Pérez-Collazos
    Departamento de Agricultura y Economía Agraria, Escuela Politécnica Superior de Huesca, Universidad de Zaragoza, Huesca, Spain
    Plant Biol (Stuttg) 10:492-501. 2008
    b>Ferula loscosii (Lange) Willk (Apiaceae) is a threatened endemic species native to the Iberian Peninsula. The plant has a narrow and disjunct distribution in three regions, NE, C and SE Spain...
  73. ncbi Increasing the cisplatin cytotoxicity and cisplatin-induced DNA damage by conferone in 5637 cells
    Vajiheh Neshati
    Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran
    Nat Prod Res 26:1724-7. 2012
    ..The present study was carried out to estimate the effects of conferone, a sesquiterpene-coumarin isolated from Ferula badrakema, on increasing cisplatin cytotoxicity in 5637 cells...
  74. ncbi Structural and histomorphometric evaluations of ferutinin effects on the uterus of ovariectomized rats during osteoporosis treatment
    Marzia Ferretti
    Section of Human Morphology of the Department of Biomedical Sciences, University of Modena and Reggio Emilia, Modena, Italy
    Life Sci 90:161-8. 2012
    The effects of chronic administration of Ferutinin (phytoestrogen found in the plants of genus Ferula), compared with those elicited by estradiol benzoate, were evaluated, following ovariectomy, on the uterus of ovariectomized rats as ..
  75. ncbi Natural daucane sesquiterpenes with antiproliferative and proapoptotic activity against human tumor cells
    Stefano Dall'acqua
    Dipartimento di Scienze Farmaceutiche, Universita di Padova, Padova, Italy
    Bioorg Med Chem 19:5876-85. 2011
    Plants of the genera Ferula and Ferulago are known for their complex content in bioactive secondary metabolites such as coumarins, phenylpropanoids, and sesquiterpenes. We used the ground parts of Ferula communis subsp...
  76. ncbi Bleaching of Serratia marcescens by some coumarins: a spectrophotometric study
    Ahmad Reza Shahverdi
    Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
    J Basic Microbiol 45:470-4. 2005
    ..Also in this study the effect of the other coumarins extracted from Ferula persica roots were evaluated for depigmentation of Serratia marcescens ...
  77. ncbi Asimafoetidnol: a new sesquiterpenoid coumarin from the gum resin of Ferula assa-foetida
    Debasish Bandyopadhyay
    Department of Biochemistry, DCCS, Rajbandh, Durgapur, West Bengal, Pin 713212, India
    Nat Prod Commun 6:209-12. 2011
    Chemical investigation of the gum resin of Ferula assa-foetida L...
  78. ncbi Effect of Ferula assafoetida on experimental murine Schistosoma mansoni infection
    Nashwa I Ramadan
    Department of Parasitology, Faculty of Medicine, Ain Shams University, Cairo, Egypt
    J Egypt Soc Parasitol 34:1077-94. 2004
    b>Ferula assafoetida is a hard, resinous, oily herbaceous gum belonging to plant family Umbelliferae. It is used as a traditional medicine in many parts of the world and its wide use in medicine was listed by many authors...
  79. ncbi Effects of Cymbopogon citratus and Ferula assa-foetida extracts on glutamate-induced neurotoxicity
    Ghazaleh S Tayeboon
    Department of Toxicology and Pharmacology, Faculty of Pharmacy, Tehran University of Medical Sciences, P O Box 14155 6451, Tehran, Iran
    In Vitro Cell Dev Biol Anim 49:706-15. 2013
    ..Here, we wanted to investigate the effects of Cymbopogon citratus essential oil and Ferula assa-foetida extracts treatment on glutamate-induced cell damage in a primary culture of rat cerebellar granule ..
  80. ncbi Investigating the enhancement of cisplatin cytotoxicity on 5637 cells by combination with mogoltacin
    Fatemeh Behnam Rassouli
    Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran
    Toxicol In Vitro 25:469-74. 2011
    ..The aim of this study was to determine the ability of mogoltacin, a sesquiterpene-coumarin from Ferula badrakema, to enhance cytotoxic effects of cisplatin on 5637 cells, using MTT assay, comet method, DAPI staining ..
  81. pmc Cytotoxic activities of phytochemicals from Ferula species
    Seied Mojtaba Valiahdi
    Biotechnology Research Center and School of Pharmacy, Mashhad University of Medical Sciences, 91775 1365, Mashhad, Iran
    Daru 21:39. 2013
    b>Ferula species are reputed in folk medicine for the treatment of a variety of disorders. There have been sporadic reports on the chemopreventive and chemosensitizing activities of some terpenoid coumarin derivatives from the genus Ferula...
  82. ncbi Feselol enhances the cytotoxicity and DNA damage induced by cisplatin in 5637 cells
    Samaneh Mollazadeh
    Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran
    Z Naturforsch C 66:555-61. 2011
    ..In this study, the effects of feselol, a sesquiterpene coumarin extracted from Ferula badrakema, on cisplatin cytotoxicity were investigated in 5637 cells, a TCC subline...
  83. ncbi Disesquiterpene and sesquiterpene coumarins from Ferula pseudalliacea, and determination of their absolute configurations
    Dara Dastan
    Department of Phytochemistry, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, G C, Evin, Tehran, Iran
    Phytochemistry 78:170-8. 2012
    ..methyl galbanate, farnesiferol B, and a sesquiterpene, aristolone, were isolated from a n-hexane extract of Ferula pseudalliacea roots...
  84. ncbi Individual and concomitant effects of cardioprotective programs on cardiac apelinergic system and oxidative state in L-NAME-induced hypertension
    Seeyed Ali Akbar Mahmoody
    Department of Sport Physiology, College of Physical Education and Sport Science, Tarbiat Modarres University, Tehran, Iran
    Clin Exp Hypertens 35:20-7. 2013
    The effect of aerobic training and Ferula gummosa supplementation (90 mg/kg) on apelinergic system and markers of cardiac stress in hypertensive rats were studied...
  85. ncbi Studies on volatile organic compounds of Tuber borchii and T. asa-foetida
    Maurizio D'Auria
    Dipartimento di Chimica A M Tamburro, Universita della Basilicata, Via dell Ateneo Lucano 10, 85100 Potenza, Italy
    J Chromatogr Sci 50:775-8. 2012
    ..T. asa-foetida showed a compound, toluene, not present in T. borchii, which creates the penetrating "solvent" smell of the truffle...
  86. ncbi Combination of bioautography with HPTLC-MS/NMR: a fast identification of acetylcholinesterase inhibitors from galbanum(†)
    Hamid Reza Adhami
    Department of Pharmacognosy, University of Vienna, Vienna, Austria Hamid Reza
    Phytochem Anal 24:395-400. 2013
    In the search for new natural compounds with acetylcholinesterase (AChE) inhibitory activity this study focused on galbanum, the oleo gum-resin from Ferula gummosa Boiss., which had shown AChE inhibitory activity in a screening.
  87. ncbi Chemotaxonomic significance of the essential oils of 18 Ferula species (Apiaceae) from Iran
    Mohammad Reza Kanani
    Department of Biology, Faculty of Sciences, University of Isfahan, 81746 73441 Isfahan, Iran
    Chem Biodivers 8:503-17. 2011
    To evaluate the chemotaxonomic significance of the essential oils of 23 populations of 18 Iranian Ferula species, the chemical composition of the oils was investigated by GC/FID and GC/MS. Altogether, 84 constituents, representing 81.3-99...
  88. ncbi [Study on standard of Ferula sinkinangensis seed quality classification]
    Xin Zhao
    Shenyang Agriculture University, Shenyang 110161, China
    Zhong Yao Cai 33:1366-7. 2010
    Study on the standard of Ferula sinkinangensis seed quality classification.
  89. ncbi Humulane and germacrane sesquiterpenes from Ferula lycia
    Racha Alkhatib
    Laboratoire de Pharmacognosie, E A GRIIOT, Faculte des Sciences Pharmaceutiques et Biologiques, Universite Lille Nord de France Lille 2, 3 rue du Professeur Laguesse, F 59006 Lille, France
    J Nat Prod 73:780-3. 2010
    Five new juniferol esters (1-5), along with six known humulane derivatives (6-11), were isolated from the roots of Ferula lycia, an endemic Turkish species...
  90. ncbi Antioxidant and antihaemolytic activities of Ferula foetida regel (Umbelliferae)
    S M Nabavi
    Pharmaceutical Sciences Research Center, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran
    Eur Rev Med Pharmacol Sci 15:157-64. 2011
    The Ferula genus (Umbelliferae) is a rich source of gum-resin and is much utilized in folklore medicine. This study is designed to examine antioxidant and antihaemolytic activities of Ferula foetida regel flower, stem and leaf extracts.
  91. ncbi Antimycobacterial activity of ferutinin alone and in combination with antitubercular drugs against a rapidly growing surrogate of Mycobacterium tuberculosis
    Ehab A Abourashed
    College of Pharmacy, Chicago State University, 9501 South King Drive, Chicago, IL 60628, USA
    Nat Prod Res 25:1142-9. 2011
    ..Based on this study and earlier studies with Staphylococcus aureus, the major constituent 1 may be responsible for the major part of the antimicrobial activity of the root of Ferula hermonis.
  92. ncbi Investigation of antibacterial activities of Albizia gummifera and Ferula communis on Streptococcus pneumoniae and Streptoccus pyogenes
    Abayneh Unasho
    Dilla College of Health Sciences, Dilla
    Ethiop Med J 47:25-32. 2009
    ..There is a failure to treat respiratory infections due to the emergence of antibiotic resistant strains among the most common respiratory pathogens...
  93. ncbi The enhancement of vincristine cytotoxicity by combination with feselol
    Samaneh Mollazadeh
    Department of Biology, Faculty of Sciences, Ferdowsi University of Mashhad, Mashhad, Iran
    J Asian Nat Prod Res 12:569-75. 2010
    ..In the present study, the effect of feselol, a sesquiterpene coumarin isolated from the fruits of Ferula badrakema, was investigated on VCR effectiveness...
  94. ncbi Persicasulphide C, a new sulphur-containing derivative from Ferula persica
    Mehrdad Iranshahi
    Department of Pharmacognosy, Biotechnology Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
    Nat Prod Res 23:1584-8. 2009
    A new sulphur-containing compound, persicasulphide C, was isolated from the roots of Ferula persica, and its structure was characterised by 1D- and 2D-NMR spectroscopy as well as HRMS...
  95. ncbi Disruption of mitochondrial membrane potential by ferulenol and restoration by propolis extract: antiapoptotic role of propolis
    Boussenane H Nadia
    Université de Jijel Département de Biologie Moléculaire et Cellulaire, Laboratoire de Toxicologie Moléculaire 18000 Jijel Algérie
    Acta Biol Hung 60:385-98. 2009
    ..membrane potential induced by ferulenol, a sesquiterpene prenylated coumarin derivative isolated from the plant Ferula vesceritensis . We show that ferulenol was able to induce the permeability transition pore (PTP) opening...
  96. pmc Essential oil composition analysis of three cultivars seeds of Resina ferulae from Xinjiang, China
    Xiaojin Li
    Chinese Medicine and National Medicine Research Institute of Xinjiang Uighur Autonomous Region, Urumqi 830002
    Pharmacogn Mag 7:116-20. 2011
    Three cultivars seeds of Resina ferulae were analyzed for essential oil composition, Ferula sinkiangensis K. M. Shen, Ferula fukangensis K. M. Shen, and Ferula ovina, investigated differences among different genera of medicinal R. ferulae.
  97. ncbi Antibacterial and antioxidant activities of three endemic plants from Algerian Sahara
    Elmouloud Bouchouka
    LSBO, Department of Chemistry, Annaba University, Algeria
    Acta Sci Pol Technol Aliment 11:61-5. 2012
    ..The purposes of this study were to measure the total phenolic compounds and total fl avonoid compounds, to determine antioxidant capacity, and to evaluate the antibacterial activity of three wild Saharan medicinal plants...
  98. ncbi Effect of Ferula hermonis root extract on rat skeletal muscle adaptation to exercise
    Mohammed Z Allouh
    Department of Anatomy, Faculty of Medicine, Jordan University of Science and Technology, PO Box 3030, Irbid 22110, Jordan
    Exp Biol Med (Maywood) 236:1373-8. 2011
    b>Ferula hermonis Boiss. is an aphrodisiac plant that grows in the Mediterranean region. It has been reported that treatment with acetonic extract from the root of this plant acutely increases serum testosterone in the rat...
  99. ncbi A systematic review of the potential herbal sources of future drugs effective in oxidant-related diseases
    Shirin Hasani-Ranjbar
    Endocrinology and Metabolism Research Center, and Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Inflamm Allergy Drug Targets 8:2-10. 2009
    ..This review focuses on the medicinal plants growing and having history of folk medicine in Iran and found effective as anti free radical damage in animal or human...
  100. ncbi Antimycobacterial coumarins from the sardinian giant fennel (Ferula communis)
    Giovanni Appendino
    Dipartimento di Scienze Chimiche, Alimentari, Farmaceutiche e Farmacologiche, Universita del Piemonte Orientale, Viale Ferrucci 33, 28100 Novara, Italy
    J Nat Prod 67:2108-10. 2004
    The structure of a new prenylated coumarin (E-omega-benzoyloxyferulenol, 1b) from the Sardinian giant fennel (Ferula communis) has been confirmed by synthesis...
  101. ncbi Microtubule-interacting activity and cytotoxicity of the prenylated coumarin ferulenol
    Claudia Bocca
    Department of Experimental Medicine and Oncology, University of Torino, Torino, Italy
    Planta Med 68:1135-7. 2002
    In this study we investigated biological activity of ferulenol, a prenylated 4-hydroxycoumarin from Ferula communis. Ferulenol stimulates tubulin polymerization in vitro, and inhibits the binding of radiolabeled colchicine to tubulin...