carum

Summary

Summary: A plant genus of the family Apiaceae. The seeds are used as flavoring.

Top Publications

  1. ncbi Antibacterial activity of Cuminum cyminum L. and Carum carvi L. essential oils
    Nicola S Iacobellis
    Dipartimento di Biologia, Difesa e Biotecnologie Agro Forestali, Universita degli Studi della Basilicata, Viale dell Ateneo Lucano 10, 85100 Potenza, Italy
    J Agric Food Chem 53:57-61. 2005
  2. ncbi Inhibitory effects of caraway (Carum carvi L. ) and its component on N-methyl-N'-nitro-N-nitrosoguanidine-induced mutagenicity
    Masanori Mazaki
    Department of Molecular Bacteriology, Institute of Health Biosciences, The University of Tokushima Graduate School, Japan
    J Med Invest 53:123-33. 2006
  3. doi Antioxidant and hepatoprotective potential of essential oils of coriander (Coriandrum sativum L.) and caraway (Carum carvi L.) (Apiaceae)
    Isidora Samojlik
    Department of Pharmacology and Toxicology, Hajduk Veljkova 3, 21000 Novi Sad, Serbia
    J Agric Food Chem 58:8848-53. 2010
  4. doi Relaxant effect of ethanol extract of Carum carvi on dispersed intestinal smooth muscle cells of the guinea pig
    Mohammed K Al-Essa
    Department of Physiology and Biochemistry, Faculty of Medicine, University of Jordan, Amman, Jordan
    Pharm Biol 48:76-80. 2010
  5. doi Antioxidant and antimutagenic activity of Carum copticum fruit extracts
    Maryam Zahin
    Department of Agricultural Microbiology, Faculty of Agricultural Sciences, Aligarh Muslim University, Aligarh 202002, India
    Toxicol In Vitro 24:1243-9. 2010
  6. ncbi Antitussive effect of Carum copticum in guinea pigs
    M H Boskabady
    Department of Physiology, Ghaem Medical Centre, Mashhad University of Medical Sciences, Post Code 91735, Mashhad, Iran
    J Ethnopharmacol 97:79-82. 2005
  7. doi Anticonvulsant and depressant effects of aqueous extracts of Carum copticum seeds in male rats
    Mohammad Ebrahim Rezvani
    Department of Physiology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
    Epilepsy Behav 22:220-5. 2011
  8. ncbi Diuretic activity of the aqueous extracts of Carum carvi and Tanacetum vulgare in normal rats
    Sanaa Lahlou
    UFR Physiology Pharmacology, Laboratory of Animal Physiology, Department of Biology, Fez, Morocco
    J Ethnopharmacol 110:458-63. 2007
  9. ncbi Suppressive effects of caraway (Carum carvi) extracts on 2, 3, 7, 8-tetrachloro-dibenzo-p-dioxin-dependent gene expression of cytochrome P450 1A1 in the rat H4IIE cells
    B Naderi-Kalali
    Department of Medical Biotechnology, Faculty of Medical Sciences, Tarbiat Modarres University, P O BOX 14115 111, Tehran, Iran
    Toxicol In Vitro 19:373-7. 2005
  10. ncbi Molluscicidal activity of Ferula asafoetida, Syzygium aromaticum and Carum carvi and their active components against the snail Lymnaea acuminata
    Pradeep Kumar
    Department of Zoology, DDU Gorakhpur University, Gorakhpur, UP 273 009, India
    Chemosphere 63:1568-74. 2006

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Publications85

  1. ncbi Antibacterial activity of Cuminum cyminum L. and Carum carvi L. essential oils
    Nicola S Iacobellis
    Dipartimento di Biologia, Difesa e Biotecnologie Agro Forestali, Universita degli Studi della Basilicata, Viale dell Ateneo Lucano 10, 85100 Potenza, Italy
    J Agric Food Chem 53:57-61. 2005
    Essential oils extracted by hydrodistillation from fruits of Cuminum cyminum L. and Carum carvi L. were analyzed by gas chromatography (GC) and GC-mass spectrometry (MS). The main components of C...
  2. ncbi Inhibitory effects of caraway (Carum carvi L. ) and its component on N-methyl-N'-nitro-N-nitrosoguanidine-induced mutagenicity
    Masanori Mazaki
    Department of Molecular Bacteriology, Institute of Health Biosciences, The University of Tokushima Graduate School, Japan
    J Med Invest 53:123-33. 2006
    ..These results indicate that caraway does not directly inactivate MNNG and that Ogt-O6-methylguanine-DNA methyltransferase may be involved in the antimutagenic activity of caraway...
  3. doi Antioxidant and hepatoprotective potential of essential oils of coriander (Coriandrum sativum L.) and caraway (Carum carvi L.) (Apiaceae)
    Isidora Samojlik
    Department of Pharmacology and Toxicology, Hajduk Veljkova 3, 21000 Novi Sad, Serbia
    J Agric Food Chem 58:8848-53. 2010
    Essential oils of Coriandrum sativum L. and Carum carvi L...
  4. doi Relaxant effect of ethanol extract of Carum carvi on dispersed intestinal smooth muscle cells of the guinea pig
    Mohammed K Al-Essa
    Department of Physiology and Biochemistry, Faculty of Medicine, University of Jordan, Amman, Jordan
    Pharm Biol 48:76-80. 2010
    The present study investigates the direct effects of Carum carvi L. (Apiaceae) ethanol extract on dispersed intestinal smooth muscle cells (SMC) of guinea pigs...
  5. doi Antioxidant and antimutagenic activity of Carum copticum fruit extracts
    Maryam Zahin
    Department of Agricultural Microbiology, Faculty of Agricultural Sciences, Aligarh Muslim University, Aligarh 202002, India
    Toxicol In Vitro 24:1243-9. 2010
    The ajowain (Carum copticum (L.)) is a popular spice and traditionally used in Indian system of medicine. Considering the importance of natural products in modern phytomedicine, the antioxidant and antimutagenic activities of C...
  6. ncbi Antitussive effect of Carum copticum in guinea pigs
    M H Boskabady
    Department of Physiology, Ghaem Medical Centre, Mashhad University of Medical Sciences, Post Code 91735, Mashhad, Iran
    J Ethnopharmacol 97:79-82. 2005
    Several therapeutic effects including anti-asthma and dyspnea have been described for the seeds of Carum copticum In previous studies the relaxant and anticholinergic (functional antagonism) effects, histamine (H(1)) inhibitory effect of ..
  7. doi Anticonvulsant and depressant effects of aqueous extracts of Carum copticum seeds in male rats
    Mohammad Ebrahim Rezvani
    Department of Physiology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
    Epilepsy Behav 22:220-5. 2011
    In this study, the effects of aqueous extracts of Carum copticum seeds (CCS) were evaluated in kindling models of epilepsy. Additionally, the sedative and anxiolytic effects of the extract were assessed...
  8. ncbi Diuretic activity of the aqueous extracts of Carum carvi and Tanacetum vulgare in normal rats
    Sanaa Lahlou
    UFR Physiology Pharmacology, Laboratory of Animal Physiology, Department of Biology, Fez, Morocco
    J Ethnopharmacol 110:458-63. 2007
    In the Moroccan traditional medicine, the ripe fruits of Carum carvi L. (Apiaceae) and the leaves of Tanacetum vulgare L. (Asteraceae/Compositae), two widely available plant materials, are used as diuretics...
  9. ncbi Suppressive effects of caraway (Carum carvi) extracts on 2, 3, 7, 8-tetrachloro-dibenzo-p-dioxin-dependent gene expression of cytochrome P450 1A1 in the rat H4IIE cells
    B Naderi-Kalali
    Department of Medical Biotechnology, Faculty of Medical Sciences, Tarbiat Modarres University, P O BOX 14115 111, Tehran, Iran
    Toxicol In Vitro 19:373-7. 2005
    ..This study was carried out for assessment of the genomic and proteomic effects of caraway (Carum carvi) extracts containing high levels of both flavonoids and steroid-like substances on ethoxy resorufin ..
  10. ncbi Molluscicidal activity of Ferula asafoetida, Syzygium aromaticum and Carum carvi and their active components against the snail Lymnaea acuminata
    Pradeep Kumar
    Department of Zoology, DDU Gorakhpur University, Gorakhpur, UP 273 009, India
    Chemosphere 63:1568-74. 2006
    ..of dried root latex powder of Ferula asafoetida, flower-bud powder of Syzygium aromaticum and seed powder of Carum carvi against the snail Lymnaea acuminata was studied...
  11. doi Raman analysis of caraway (Carum carvi L.) single fruits. Evaluation of essential oil content and its composition
    K Seidler-Lozykowska
    Institute of Natural Fibres and Medicinal Plants, Poznan, Poland
    J Agric Food Chem 58:5271-5. 2010
    FT-Raman spectroscopy was applied for in situ analysis of single and intact fruits obtained from a diverse caraway (Carum carvi L.) collection...
  12. ncbi Dose-response efficacy of caraway (Carum carvi L.) on tissue lipid peroxidation and antioxidant profile in rat colon carcinogenesis
    Muthaiyan Kamaleeswari
    Department of Biochemistry, Annamalai University, Annamalainagar, 608 002, Tamilnadu, India
    J Pharm Pharmacol 58:1121-30. 2006
    ..This study was conducted to examine the efficacy of different doses of dietary caraway (Carum carvi L.) on tissue lipid peroxidation (LPO) and antioxidant profile in rat colon carcinogenesis...
  13. ncbi The analgesic effect of Carum copticum extract and morphine on phasic pain in mice
    Mohammad Hossein Dashti-Rahmatabadi
    Department of Physiology Sahid Sadughi Medical University, Yazd, Iran
    J Ethnopharmacol 109:226-8. 2007
    Pain is a universal complaint, which needs further investigations for new pain relieving agents. Carum copticum (L...
  14. doi Fatty acid and essential oil composition of three Tunisian caraway (Carum carvi L.) seed ecotypes
    Bochra Laribi
    National Agronomic Institute of Tunisia, 43 Av Charles Nicolle 1082, Tunis, Tunisia bochra
    J Sci Food Agric 90:391-6. 2010
    The essential oil and fatty acid composition of Tunisian annual caraway (Carum carvi L.) seeds from three ecotypes was investigated by gas chromatography and gas chromatography-mass spectrometry analyses.
  15. ncbi Studies on the antihypertensive, antispasmodic, bronchodilator and hepatoprotective activities of the Carum copticum seed extract
    A H Gilani
    Department of Biological and Biomedical Sciences, The Aga Khan University, Karachi 74800, Pakistan
    J Ethnopharmacol 98:127-35. 2005
    ..antispasmodic, bronchodilator and hepatoprotective activities of the aqueous-methanolic extract of Carum copticum Benth. seeds (CSE) to rationalize some of its traditional uses...
  16. ncbi Effect of dietary caraway (Carum carvi L.) on aberrant crypt foci development, fecal steroids, and intestinal alkaline phosphatase activities in 1,2-dimethylhydrazine-induced colon carcinogenesis
    Muthaiyan Kamaleeswari
    Department of Biochemistry and Biotechnology, Annamalai University, Annamalainagar 608 002, Tamilnadu, India
    Toxicol Appl Pharmacol 214:290-6. 2006
    ..Caraway (Carum carvi L. Umbelliferae) is a shrub with a long history as a medicinal plant since ancient times...
  17. ncbi Antioxidant and biocidal activities of Carum nigrum (seed) essential oil, oleoresin, and their selected components
    Gurdip Singh
    Chemistry Department, D D U Gorakhpur University, Gorakhpur 273009, India
    J Agric Food Chem 54:174-81. 2006
    In the present study, chemical constituents of the essential oil and oleoresin of the seed from Carum nigrum obtained by hydrodistillation and Soxhlet extraction using acetone, respectively, have been studied by GC and GC-MS techniques...
  18. ncbi Chemistry, antioxidant, antibacterial and antifungal activities of volatile oils and their components
    Laura De Martino
    Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Salerno, Via Ponte Don Melillo, 84084 Fisciano, Salerno, Italy
    Nat Prod Commun 4:1741-50. 2009
    ..Analysis showed that three oils (Carum carvi L., Verbena officinalis L. and Majorana hortensis L...
  19. ncbi Comparative study of the major Iranian cereal cultivars and some selected spices in relation to support Aspergillus parasiticus growth and aflatoxin production
    Mansour Zare
    Faculty of Veterinary Sciences, Azad University, Garmsar, Iran
    Iran Biomed J 12:229-36. 2008
    ..In this study, the ability of a toxigenic Aspergillus parasiticus to produce various aflatoxins on major Iranian cereals was evaluated with special focus on plant susceptibility to toxin production at cultivar level...
  20. ncbi Hypolipidemic effect of aqueous extract of Carum carvi (black Zeera) seeds in diet induced hyperlipidemic rats
    Muhammad Rashad Saghir
    Department of Pharmacology, University of Health Sciences, Khayaban e Jamia Punjab, Lahore, Pakistan
    Pak J Pharm Sci 25:333-7. 2012
    ..The purpose of the present study was to assess the effect of aqueous extract of Carum carvi seeds in diet induced hyperlipidemia in rats...
  21. doi In vitro lethal effect of ajowan (Trachyspermum ammi L.) essential oil on hydatid cyst protoscoleces
    Mohammad Moazeni
    School of Veterinary Medicine, Shiraz University, Shiraz 71345 1731, Iran
    Vet Parasitol 187:203-8. 2012
    ..The results of this study revealed that the EO of ajowan is rich in thymol, γ-terpinene and p-cymene, has high scolicidal power and it may be used as a natural scolicidal agent...
  22. doi Evaluation of antioxidant and antimicrobial activities of essential oils from Carum copticum seed and Ferula assafoetida latex
    Gholamreza Kavoosi
    Inst of Biotechnology, Faculty of Agriculture, Univ of Shiraz, Shiraz, 71441 65186, Iran
    J Food Sci 78:T356-61. 2013
    b>Carum copticum and Ferula assafoetida have several medicinal properties including antispasmodic, carminative, sedative, analgesic, and antiseptic...
  23. ncbi In vitro and in vivo anti-plasmodial activity of essential oils, including hinokitiol
    Ryuichi Fujisaki
    Teikyo University Hospital, School of Medicine, Teikyo University, Tokyo, Hachioji, Tokyo, Japan
    Southeast Asian J Trop Med Public Health 43:270-9. 2012
    ..Caraway oil and hinokitiol dissolved in carrier oil, applied to the skin of hairless mice caused high levels in the blood, with concentrations exceeding their IC50 values...
  24. ncbi Fumigant toxicity of plant essential oils against Camptomyia corticalis (Diptera: Cecidomyiidae)
    Jun Ran Kim
    Research Institute for Agriculture and Life Science, Seoul National University, Seoul 151 921, Republic of Korea
    J Econ Entomol 105:1329-34. 2012
    ..027 mg/cm3). The LC50 of caraway (Carum carvi L.) seed, armoise (Artemisia vulgaris L.), clary sage (Salvia sclarea L.), oregano (Origanum vulgare L...
  25. ncbi Preliminary evaluation of antimicrobial activity of cream formulated with essential oil of Trachyuspermum ammi
    Gilani Rubina Gilani
    Department of Chemistry, University of Engineering and Technology, Lahore, Pakistan
    Pak J Pharm Sci 26:893-6. 2013
    ..The oil was used to formulate a cream and the pH, physiochemical stability, phase separation and dermal irritation of cream were investigated. The cream was examined for healing wound in rabbits in comparison with Iodine tincture. ..
  26. doi Insecticidal and acetylcholine esterase inhibition activity of Apiaceae plant essential oils and their constituents against adults of German cockroach (Blattella germanica)
    Hwa Jeong Yeom
    Division of Forest Insect Pests and Diseases, Korea Forest Research Institute, Seoul 130 712, Republic of Korea
    J Agric Food Chem 60:7194-203. 2012
    ..Of the 11 Apiaceae plant essential oils tested, dill (Anethum graveolens), carvi (Carum carvi), and cumin (Cuminum cyminum) demonstrated >90% fumigant toxicity against adult male German cockroaches ..
  27. ncbi Essential oils as potential adulticides against two populations of Aedes aegypti, the laboratory and natural field strains, in Chiang Mai province, northern Thailand
    Dana Chaiyasit
    Department of Parasitology, Chiang Mai University, Chiang Mai 50200, Thailand
    Parasitol Res 99:715-21. 2006
    Essential oils derived from five plant species, celery (Apium graveolens), caraway (Carum carvi), zedoary (Curcuma zedoaria), long pepper (Piper longum), and Chinese star anise (Illicium verum), were subjected to investigation of ..
  28. ncbi Element analysis and biological studies on ten oriental spices using XRF and Ames test
    Barakat A Al-Bataina
    Physics Department, Yarmouk University, Irbid, Jordan
    J Trace Elem Med Biol 17:85-90. 2003
    ..XRF): nutmeg (Myristica fragrans), coriander (Coriandrum sativum), safflower (Carthamus tinctorius), caraway (Carum carvi), Sicilian sumac (Rhus coriaria), aniseed (Anisum vulgare), black pepper (Piper nigrum), cardamom (Elettaria ..
  29. doi Seed rain and its relationship with above-ground vegetation of degraded Kobresia meadows
    Zhan Huan Shang
    International Centre for Tibetan Plateau Ecosystem Management, State Key Laboratory of Grassland Farming Systems, College of Pastoral Agriculture Science and Technology, Lanzhou University, No 768, Jiayuguan West Road, Lanzhou, Gansu 730020, China
    J Plant Res 126:63-72. 2013
    ..meadow on the Tibetan plateau is exacerbated by the seed input of weed species (such as Oxytropis ochrocephala, Carum carvi, Aconitum pendulum, Pedicularis kansuensis in this study)...
  30. doi Antioxidant activity of medicinal plant extracts in cookies
    Aleksandra Mišan
    Inst for Food Technology, Bulevar Cara Lazara 1, 21000 Novi Sad, Serbia
    J Food Sci 76:C1239-44. 2011
    ..Finally, "Vitalplant" extract addition (2%, 4%, and 6%) improved antioxidant activity and oxidative stability of the cookies in dose-dependent manner...
  31. doi Gut and airways relaxant effects of Carum roxburghianum
    Munasib Khan
    Natural Products Research Unit, Department of Biological and Biomedical Sciences, The Aga Khan University Medical College, Karachi 74800, Pakistan
    J Ethnopharmacol 141:938-46. 2012
    b>Carum roxburghianum is traditionally used in hyperactive gastrointestinal and respiratory disorders...
  32. ncbi [Influence of spiced feed additives on taste of hen's eggs]
    Th Richter
    Institut für Lebensmittelhygiene, Veterinärmedizinische Fakultät, Universitat Leipzig
    Berl Munch Tierarztl Wochenschr 115:200-2. 2002
    The effect of the spices garlic (Allium sativum), extract from garlic, sage (Salvia officinalis), caraway (Carum carvi), peppermint (Mentha piperita), fennel (Foeniculum vulgare), thyme (Thymus vulgaris), paprika (Capsicum annuum), ..
  33. doi Loop-mediated isothermal amplification (LAMP): methods for plant species identification in food
    Felix Focke
    Hamburg School of Food Science, Institute of Food Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg, Germany
    J Agric Food Chem 61:2943-9. 2013
    ..An existing (real-time) PCR method (for the detection of spices) was used for comparison. It could be shown that the developed LAMP methods have potential as alternative strategies to PCR in DNA-based analysis...
  34. doi Anti-leishmanial and toxicity activities of some selected Iranian medicinal plants
    Hamidreza Kheiri Manjili
    Department of Nano Biotechnology, Tarbiat Modarres University, Tehran, Iran
    Parasitol Res 111:2115-21. 2012
    ..Four plants, Caesalpinia gilliesii, Satureia hortensis, Carum copticum heirm, and Thymus migricus, displayed high anti-leishmanial activity (IC50, 9.76 ± 1.27, 15...
  35. doi The effect of Carum Copticum extract on acetylcholine induced contraction in isolated rat's ileum
    Seyed Hassan Hejazian-Y
    Herbal Medicine Research Center, School of Medicine, Shahid Sadughi University of Medical Sciences and Health Services, Yazd, Iran
    J Acupunct Meridian Stud 2:75-8. 2009
    ..It has been reported that Carum Copticum is a bactericidal agent and possesses anticholinergic, antihistaminic and b-adrenergic stimulatory ..
  36. ncbi Comparison of different extraction methods for the determination of essential oils and related compounds from aromatic plants and optimization of solid-phase microextraction/gas chromatography
    Jana Richter
    Institute of Bioanalytical Sciences IBAS, Center of Life Sciences, Anhalt University of Applied Sciences, Strenzfelder Allee 28, 06406, Bernburg, Germany
    Anal Bioanal Chem 387:2207-17. 2007
    ..caraway (Carum carvi L.), sage (Salvia officinalis L.), and thyme (Thymus vulgaris L.) have been compared...
  37. doi Chemistry and antioxidant activity of essential oil and oleoresins of black caraway (Carum bulbocastanum) fruits: Part 69
    Inder Pal Singh Kapoor
    Chemistry Department, D D U Gorakhpur University, Gorakhpur 273009, India
    J Sci Food Agric 90:385-90. 2010
    ..The paper also explains the importance of the extracted oil and oleoresins in the antioxidant activities of target plant species...
  38. ncbi The reno-protective effect of aqueous extract of Carum carvi (black zeera) seeds in streptozotocin induced diabetic nephropathy in rodents
    Soban Sadiq
    Department of Pharmacology, University of Health Sciences, Khayaban e Jamia Punjab, Lahore, Pakistan
    Saudi J Kidney Dis Transpl 21:1058-65. 2010
    To assess the effect of aqueous extract of Carum carvi seeds in experimentally induced diabetic nephropathy (DN) in rodents, we studied 48 adult male Wistar rats divided into 4 groups: normal controls (group A), diabetes positive control ..
  39. ncbi Isothymol in Ajowan essential oil
    Chahrazed Bekhechi
    Laboratoire des Produits Naturels, Departement de Biologie, Université Abou Bekr Belkaid, BP 119, Tlemcen, Algeria
    Nat Prod Commun 5:1107-10. 2010
    ..In other cases, thymol is the predominant constituent...
  40. doi Novel compound from Trachyspermum ammi (Ajowan caraway) seeds with antibiofilm and antiadherence activities against Streptococcus mutans: a potential chemotherapeutic agent against dental caries
    R Khan
    Interdisciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh, India
    J Appl Microbiol 109:2151-9. 2010
    ..The objective of this study was to isolate and characterize the active compound from Trachyspermum ammi seeds, exhibiting antibiofilm activity against Streptococcus mutans, a major causal organism of dental caries...
  41. ncbi Caraway and caper: potential anti-hyperglycaemic plants in diabetic rats
    M Eddouks
    Laboratory of Endocrinian Physiology, FSTE Boutalamine and Pharmacology, EDDOUKS, UFR PNPE, BP 21, Errachidia 52000, Morocco
    J Ethnopharmacol 94:143-8. 2004
    The hypoglycaemic effect of aqueous extracts of Carum carvi (CC) and Capparis spinosa L. (CS) fruit were investigated in normal and streptozotocin (STZ) diabetic rats...
  42. ncbi Bait formulations of molluscicides and their effects on biochemical changes in the ovotestis of snail Lymnaea acuminata (Mollusca; Gastropoda:Lymnaeidae)
    Pradeep Kumar
    Department of Zoology, Malacology Laboratory, DDU Gorakhpur University, Gorakhpur, UP, India
    Rev Inst Med Trop Sao Paulo 53:271-5. 2011
    ..molluscicidal component of Ferula asafoetida (ferulic acid, umbelliferone), Syzygium aromaticum (eugenol) and Carum carvi (limonene) on biochemical changes in the ovotestis of snail Lymnaea acuminata were studied...
  43. pmc Anti-proliferative and pro-apoptotic effect of carvacrol on human hepatocellular carcinoma cell line HepG-2
    Qing Hua Yin
    Department of Medical Oncology, the First Affiliated Hospital of University of South China, Hengyang, 421001, People s Republic of China
    Cytotechnology 64:43-51. 2012
    Carvacrol is one of the members of monoterpene phenol and is present in the volatile oils of Thymus vulgaris, Carum copticum, origanum and oregano...
  44. ncbi Antifungal activity of some essential oils against toxigenic Aspergillus species
    Alireza Alizadeh
    Department of Plant Pathology, College of Agriculture and Natural Resources University of Tehran, Karaj 31587 77871, Iran
    Commun Agric Appl Biol Sci 75:761-7. 2010
    ..activity of the essential oils of Zataria multiflora, Thymus migricus, Satureja hortensis, Foeniculum vulgare, Carum capticum and thiabendazol fungicide on survival and growth of different species of Aspergillus...
  45. doi Heart and kidney oxidative stress status in septic rats treated with caraway extracts
    Abolfazl Dadkhah
    Department of Medicine, Faculty of Medicine, Qom Branch, Islamic Azad University, P O Box 37185 364, Qom, Iran
    Pharm Biol 49:679-86. 2011
    b>Carum carvi L., (Umbelliferae) known as caraway, is a famous traditional herbal plant supposed to contain active components with pharmacological properties.
  46. ncbi Antimicrobial activity of plant essential oils against bacterial and fungal species involved in food poisoning and/or food decay
    Brînduşa Elena Lixandru
    Cantacuzino National Institute of Research Development for Microbiology and Immunology, Bucharest, Romania
    Roum Arch Microbiol Immunol 69:224-30. 2010
    ..sage (Salvia officinalis L.), fennel (Foeniculum vulgare L.), spearmint (Mentha spicata L.) and carraway (Carum carvi L...
  47. doi Inhibitory effects of dietary caraway essential oils on 1,2-dimethylhydrazine-induced colon carcinogenesis is mediated by liver xenobiotic metabolizing enzymes
    A Dadkhah
    Department of Clinical Biochemistry, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran
    Nutr Cancer 63:46-54. 2011
    ....
  48. doi An attempt of postharvest orange fruit rot control using essential oils from Mediterranean plants
    Ippolito Camele
    Department of Biology, Protection and Agro Forestry Biotechnology, University of Basilicata, Potenza, Italy
    J Med Food 13:1515-23. 2010
    ..Family Lamiaceae), Verbena officinalis (Family Verbenaceae), and Pimpinella anisum, Foeniculum vulgare, and Carum carvi (Family Apiaceae). Because preliminary in vitro experiments showed that only the oils from V. officinalis, T...
  49. doi Insecticidal activity of essential oil of Carum Carvi fruits from China and its main components against two grain storage insects
    Rui Fang
    Protection and Utilization of Traditional Chinese Medicine of Beijing Area Major Laboratory, Beijing Normal University, Haidian District, Beijing 100875, China
    Molecules 15:9391-402. 2010
    During our screening program for agrochemicals from Chinese medicinal herbs and wild plants, the essential oil of Carum carvi fruits was found to possess strong contact toxicity against Sitophilus zeamais and Tribolium castaneum adults, ..
  50. ncbi Essential oils in the treatment of intestinal dysbiosis: A preliminary in vitro study
    Jason A Hawrelak
    School of Health and Human Sciences, Southern Cross University
    Altern Med Rev 14:380-4. 2009
    ....
  51. ncbi Solid phase microextraction with gas chromatography-mass spectrometry: a very rapid method for identification of volatile organic compounds emitted by Carum copticum
    Shiva Dehghan Abkenar
    Faculty of Science, Department of Chemistry, University of Tehran, Tehran, Iran
    Nat Prod Res 20:850-9. 2006
    ..microextraction coupled with gas chromatography-mass spectrometry was used to identify the volatile components of Carum copticum (C. copticum) cultivated in Iran...
  52. ncbi Dose dependent inhibitory effect of dietary caraway on 1,2-dimethylhydrazine induced colonic aberrant crypt foci and bacterial enzyme activity in rats
    Kumaraswami Deeptha
    Department of Biochemistry and Biotechnology, Annamalai University, Annamalainagar 608 002, Tamilnadu, India
    Invest New Drugs 24:479-88. 2006
    Colon cancer has become one of the major causes of cancer mortality. We determined the effect of caraway (Carum carvi L...
  53. ncbi Cholesterol and triglycerides lowering activities of caraway fruits in normal and streptozotocin diabetic rats
    A Lemhadri
    UFR PNPE B P 21, Errachidia 52000, Morocco
    J Ethnopharmacol 106:321-6. 2006
    ..of this study was to examine the effect of single and repeated oral administration of the aqueous extract of Carum carvi L...
  54. ncbi In vitro susceptibility of Helicobacter pylori to botanical extracts used traditionally for the treatment of gastrointestinal disorders
    Gail B Mahady
    Program for Collaborative Research in the Pharmaceutical Sciences, University of Illinois at Chicago, 833 S Wood Street M C 877, 60612, USA
    Phytother Res 19:988-91. 2005
    ..Botanical extracts with a MIC of 100 microg/mL included Carum carvi (seed), Elettaria cardamomum (seed), Gentiana lutea (roots), Juniper communis (berry), Lavandula ..
  55. ncbi Evaluation of contraceptive activity of a mineralo-herbal preparation in Sprague-Dawley rats
    Shobha Rani Srivastava
    Endocrinology Division, Central Drug Research Institute, Lucknow 226 001, India
    Contraception 72:454-8. 2005
    ....
  56. pmc Molecular epidemiology of Salmonella enterica serovar Agona: characterization of a diffuse outbreak caused by aniseed-fennel-caraway infusion
    W Rabsch
    National Reference Centre for Salmonella and other Enteric Pathogens, Robert Koch Institute, Wernigerode, Germany
    Epidemiol Infect 133:837-44. 2005
    ..It is suggested that strains of S. Agona will continue to be of public health concern, and that phage typing together with PFGE typing should be applied as reliable and rapid tools for epidemiological subtyping and future monitoring...
  57. ncbi Study on the transfer of components of Aetheroleum carvi and Aetheroleum foeniculi oils
    C Lado
    Department of Biochemistry and Food Technology, Budapest University of Technology and Economics, H 1111 Budapest, Muegyetem rkp 3 9, Hungary
    Fitoterapia 76:166-72. 2005
    The transfer through a membrane of the main organic components and mineral elements of Carum carvi and Foeniculum vulgare volatile oils was studied. The transfer was studied from buffer solution pH 1.1 (stomach) and pH 6...
  58. ncbi Antioxidant activity of the aqueous extracts of spicy food additives--evaluation and comparison with ascorbic acid in in-vitro systems
    S Satyanarayana
    Pharmacology Division, Department of Pharmaceutical Services, Andhra University, Visakhapatnam, Andhra Pradesh 530 003, India
    J Herb Pharmacother 4:1-10. 2004
    The antioxidant activity of the aqueous extracts of five umbelliferous fruits--caraway (Carum carvi), coriander (Coriandrum sativum), cumin (Cuminum cyminum), dill (Anethum graveolens) and fennel (Foeniculum vulgare)--were investigated ..
  59. ncbi Relaxant effects of different fractions of essential oil from Carum copticum on guinea pig tracheal chains
    M H Boskabady
    Department of Physiology, Ghaem Medical Centre, Mashhad, Iran
    Phytother Res 17:1145-9. 2003
    ..and anticholinergic (functional antagonism), histamine(H1) inhibitory, and xanthine-like activity effect of Carum copticum have been demonstrated on guinea pig tracheal chains...
  60. ncbi Sensitivity-dependent hierarchical receptor codes for odors
    Hiroshi Hamana
    Life Electronics Laboratory, National Institute of Advanced Industrial Science and Technology, Amagasaki, Hyogo, Japan
    Chem Senses 28:87-104. 2003
    ....
  61. ncbi Studies on essential oils: part 10; antibacterial activity of volatile oils of some spices
    G Singh
    Chemistry Department, DDU Gorakhpur University, Gorakhpur 273009, India
    Phytother Res 16:680-2. 2002
    The essential oils extracted from the seeds of seven spices, Anethum graveolens, Carum capticum, Coriandrum sativum, Cuminum cyminum, Foeniculum vulgare, Pimpinella anisum and Seseli indicum have been studied for antibacterial activity ..
  62. ncbi Water-soluble constituents of caraway: aromatic compound, aromatic compound glucoside and glucides
    Tetsuko Matsumura
    Showa Pharmaceutical University, Higashi Tamagawagakuen 3, Machida, Tokyo, 194 8543, Japan
    Phytochemistry 61:455-9. 2002
    From the water-soluble portion of the methanolic extract of caraway (fruit of Carum carvi L.), an aromatic compound, an aromatic compound glucoside and a glucide were isolated together with 16 known compounds...
  63. ncbi Systematic review: herbal medicinal products for non-ulcer dyspepsia
    J Thompson Coon
    Department of Complementary Medicine, School of Sport and Health Sciences, University of Exeter, UK
    Aliment Pharmacol Ther 16:1689-99. 2002
    ..Herbal medicinal products are often used for the relief of dyspeptic symptoms...
  64. ncbi Occupational rhinoconjunctivitis and food allergy because of aniseed sensitization
    Juan Jesús García-González
    Allergy Section, Complejo Hospitalario Carlos Haya, Malaga, Spain
    Ann Allergy Asthma Immunol 88:518-22. 2002
    ..Aniseed is a spice frequently used in Mediterranean cooking and, as with other Umbelliferae, it has been involved in clinical allergy...
  65. ncbi Ethnopharmacological survey of plants used in the traditional treatment of hypertension and diabetes in south-eastern Morocco (Errachidia province)
    A Tahraoui
    UFR Physiology Pharmacology, Laboratory of Animal Physiology, Department of Biology, Faculty of Sciences, Dhar El Mehraz, USMBA, BP 1976 Atlas Fez, Morocco
    J Ethnopharmacol 110:105-17. 2007
    ..region, the most frequently used plants to treat diabetes include Ajuga iva, Allium cepa, Artemisia herba-alba, Carum carvi, Lepidium sativum, Nigella sativa, Olea europaea, Peganum harmala, Phoenix dactylifera, Rosmarinus ..
  66. ncbi Use of gas chromatography-mass spectrometry combined with resolution methods to characterize the essential oil components of Iranian cumin and caraway
    Mehdi Jalali-Heravi
    Department of Chemistry, Sharif University of Technology, P O Box, 11365 9516 Tehran, Iran
    J Chromatogr A 1143:215-26. 2007
    ..64%) and in caraway are gamma-terpinene (24.40%), 2-methyl-3-phenyl-propanal (13.20%) and 2, 4(10)-thujadien (14.02%). In spite of different cultivation conditions, there are 28 components which are common between the two seeds...
  67. ncbi Aromatic plant-derived essential oil: an alternative larvicide for mosquito control
    B Pitasawat
    Department of Parasitology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand
    Fitoterapia 78:205-10. 2007
    Five aromatic plants, Carum carvi (caraway), Apium graveolens (celery), Foeniculum vulgare (fennel), Zanthoxylum limonella (mullilam) and Curcuma zedoaria (zedoary) were selected for investigating larvicidal potential against mosquito ..
  68. doi Pharmacokinetic interaction of some antitubercular drugs with caraway: implications in the enhancement of drug bioavailability
    B S Sachin
    Division of Pharmacology, Indian Institute of Integrative Medicine CSIR, Formerly Regional Research Laboratory, Jammu Tawi, India
    Hum Exp Toxicol 28:175-84. 2009
    ..the pharmacokinetic interaction of selected anti-TB drugs with a natural product (CC-1a) derived from caraway (Carum carvi, L.) seed...
  69. doi Fumigant antitermitic activity of plant essential oils and components from Ajowan ( Trachyspermum ammi ), Allspice ( Pimenta dioica ), caraway ( Carum carvi ), dill ( Anethum graveolens ), Geranium ( Pelargonium graveolens ), and Litsea ( Litsea cubeba )
    Seon Mi Seo
    Division of Forest Insect Pests and Diseases, Korea Forest Research Institute, Seoul 130 712, Republic of Korea
    J Agric Food Chem 57:6596-602. 2009
    ..was observed with the essential oils of ajowan ( Trachyspermum ammi ), allspice ( Pimenta dioica ), caraway ( Carum carvi ), dill ( Anethum graveolens ), geranium ( Pelargonium graveolens ), and litsea ( Litsea cubeba )...
  70. doi An antibacterial and antifungal phenylpropanoid from Carum montanum (Coss. et Dur.) Benth. et Hook
    Hocine Laouer
    Department of Biology, University of Setif, Mabouda, 19000, Setif, Algeria
    Phytother Res 23:1726-30. 2009
    The volatile constituents of the aerial parts of Carum montanum (Coss. et Dur.) Benth. et Hook. were analysed by GC-FID and GC-MS, and the main component was isolated and identified as nothoapiole...
  71. ncbi The potential application of plant essential oils as natural preservatives against Escherichia coli O157:H7
    A Fazlara
    Department of Food Hygiene, Faculty of Veterinary Medicine, Shahid Chamran University, P O Box 61355 145, Ahvaz, Iran
    Pak J Biol Sci 11:2054-61. 2008
    Investigation were carried out to compare the efficiency of three plant essential oils; Zataria multiflora, Carum carvi and Mentha piperita as natural food preservatives. The effect of these plant essential oils at concentrations of 0...
  72. ncbi Evaluation of antibacterial activity of selected Iranian essential oils against Staphylococcus aureus and Escherichia coli in nutrient broth medium
    Mohammad Mohsenzadeh
    Department of Food Hygiene and Public Health, Ferdowsi University of Mashhad, P O Box 91775 1793, Mashhad, Iran
    Pak J Biol Sci 10:3693-7. 2007
    ..01 to 15%) of thyme (Thymus vulgaris), peppermint (Mentha piperita L.) caraway seed (Carum carvi), fennel (Foeniculum vulgar), tarragon (Artmesia dracunculus) and pennyroyal (Mentha pullegium) essential ..
  73. doi Kinetics of enzyme inhibition by active molluscicidal agents ferulic acid, umbelliferone, eugenol and limonene in the nervous tissue of snail Lymnaea acuminata
    Pradeep Kumar
    Department of Zoology, DDU Gorakhpur University, Gorakhpur 273009, UP India
    Phytother Res 23:172-7. 2009
    Ferulic acid, umbelliferone (Ferula asafoetida), eugenol (Syzygium aromaticum) and limonene (Carum carvi) are active molluscicidal components that inhibited the activity of alkaline phosphatase and acetylcholinesterase in in vivo and in ..
  74. ncbi Water-soluble constituents of caraway: carvone derivatives and their glucosides
    Tetsuko Matsumura
    Showa Pharmaceutical University, Machida, Tokyo, Japan
    Chem Pharm Bull (Tokyo) 50:66-72. 2002
    ..seven glucosides were isolated from the water-soluble portion of the methanolic extract of the caraway (fruit of Carum carvi L.), and their structures were clarified by spectral investigation...
  75. doi Apoptotic activities of ethanol extracts from some Apiaceae on human leukaemia cell lines
    A Bogucka-Kocka
    Department of Pharmaceutical Botany, Medical University of Lublin, 1 Chodźki Str 20 093 Lublin Poland
    Fitoterapia 79:487-97. 2008
    ..of seven species of Apiaceae, Eryngium planum, Archangelica officinalis, Pastinaca sativa, Heracleum sibiricum, Carum carvi, Foeniculum vulgare, Levisticum officinale against ML-1--human acute myeloblastic leukaemia, J-45...
  76. ncbi Potential of biologically active plant oils to control mosquito larvae (Culex pipiens, Diptera: Culicidae) from an Egyptian locality
    Hanem Fathy Khater
    Parasitology Department, Faculty of Veterinary Medicine, Benha University, Egypt
    Rev Inst Med Trop Sao Paulo 50:107-12. 2008
    ..esculentus), mustard (Brassica compestris), olibanum (Boswellia serrata), rocket (Eruca sativa), and parsley (Carum ptroselinum), respectively. The tested oils altered some biological aspects of C...
  77. ncbi Bronchodilatory effect of Carum copticum in airways of asthmatic patients
    Mohammad Hossein Boskabady
    Department of Physiology, Ghaem Medical Centre, Mashhad University of Medical Sciences, Mashhad, Iran
    Therapie 62:23-9. 2007
    Several therapeutic effects including anti-asthma and dyspnea have been described for the seeds of Carum copticum...
  78. ncbi Toxicity of plant essential oils and their components against Lycoriella ingenua (Diptera: Sciaridae)
    Il Kwon Park
    Division of Forest Insect Pests and Diseases, Korea Forest Research Institute, Seoul 130 012, Republic of Korea
    J Econ Entomol 101:139-44. 2008
    ..ingenua was achieved with essential oils of caraway seed Carum carvi (L.)], lemongrass [Cymbopogon citratus (D.C.) Stapf...
  79. pmc Wild vascular plants gathered for consumption in the Polish countryside: a review
    Łukasz Łuczaj
    High School of Humanities and Economics in Łódź, Department of Humanities, 90 222 Łódź, Poland
    J Ethnobiol Ethnomed 3:17. 2007
    ..This paper is an ethnobotanical review of wild edible plants gathered for consumption from the end of the 18th century to the present day, within the present borders of Poland...
  80. ncbi The effect of oral administration of Carum carvi on weight, serum glucose, and lipid profile in streptozotocin-induced diabetic rats
    Fatemeh Haidari
    Department of Nutrition, Nutrition Research Center, Ahvaz Jondi Shapour University of Medical Sciences, Ahvaz, Iran
    Saudi Med J 32:695-700. 2011
    To evaluate the effect of oral administration of caraway (Carum carvi) on the blood glucose level, lipid profile, and the weight of diabetic rats.
  81. ncbi Occurrence and characterization of Colletotrichum dematium (Fr.) grove
    Zofia Machowicz-Stefaniak
    Department of Phytopathology, University of Life Sciences Lublin, Poland
    Pol J Microbiol 59:191-200. 2010
    ..C. dematium in dual culture with E. purpurascens, A. radicina, S. sclerotiorum, B. cinerea and R. solani produced an inhibition zone which indicated its capacity for antibiosis...
  82. pmc Cuminum cyminum and Carum carvi: An update
    R K Johri
    Pharmacokinetics Pharmacodynamics Toxicology Division, Indian Institute of Integrative Medicine, Jammu Tawi, India
    Pharmacogn Rev 5:63-72. 2011
    Cuminum cyminum and Carum carvi are the sources of cumin and caraway seeds respectively, which have been used since antiquity for the treatment of various indications in traditional healing systems in wide geographical areas...
  83. doi Phytotoxic activities of Mediterranean essential oils
    Luiz Fernando Rolim de Almeida
    Departamento de Botanica, Instituto de Biociencias de Botucatu, UNESP Campu de Botucatu Distrito de Rubião Júnior, S N, 18 618 000, Botucatu SP, Brazil
    Molecules 15:4309-23. 2010
    ..and Thymus vulgaris (Lamiaceae), Verbena officinalis (Verbenaceae), Pimpinella anisum, Foeniculum vulgare and Carum carvi (Apiaceae). The germination and radicle growth of tested seeds were affected in different ways by the oils...
  84. ncbi Non-invasive localization of thymol accumulation in Carum copticum (Apiaceae) fruits by chemical shift selective magnetic resonance imaging
    P V Gersbach
    Centre for Biostructural and Biomolecular Research, University of Western Sydney, Richmond, NSW, Australia
    Ann Bot 90:253-7. 2002
    Magnetic resonance imaging was used to localize the site of essential oil accumulation in fruit of Carum copticum L. (Apiaceae)...
  85. doi Breastfeeding facilitates acceptance of a novel dietary flavour compound
    Helene Hausner
    Department of Food Science, Faculty of Life Sciences, University of Copenhagen, Frederiksberg, Denmark
    Clin Nutr 29:141-8. 2010
    ..This study examines whether acceptance of a flavour compound develops over 10 exposures through mother's milk (part 1), and how such acceptance evolves after 10 exposures, on alternate days, to the same flavour in solid food (part 2)...

Research Grants4

  1. EVALUATION OF BOTANICALS FOR H .PYLORI INFECTIONS
    Gail Mahady; Fiscal Year: 2002
    ..pylori strains. Active extracts will be utilized for in vivo studies. The long-term objectives are to develop safe and effective botanical extracts for the treatment and prevention of H. pylori infections. ..
  2. Conference on Emerging Research Technologies
    Gail Mahady; Fiscal Year: 2004
    ....
  3. Botanicals for Chlamydia pneumonia infections-Revision 1
    Gail Mahady; Fiscal Year: 2005
    ..Data and active standardized extracts developed during this work will be used as the basis for future clinical trials. ..
  4. Botanicals from Central America for Menopause
    Gail Mahady; Fiscal Year: 2005
    ..Successful validation and standardization of traditional plant-based medicines used to treat menopause has great significance not only for the women of Central America but the rest of the world as well. ..