mucor

Summary

Summary: A genus of zygomycetous fungi of the family Mucoraceae, order Mucorales. It is primarily saprophytic, but may cause MUCORMYCOSIS in man from spores germinating in the lungs.

Top Publications

  1. doi Two distinct RNA-dependent RNA polymerases are required for initiation and amplification of RNA silencing in the basal fungus Mucor circinelloides
    Silvia Calo
    Departamento de Genética y Microbiología, Facultad de Biologia, Universidad de Murcia, 30100 Murcia, Spain
    Mol Microbiol 83:379-94. 2012
  2. pmc Endogenous short RNAs generated by Dicer 2 and RNA-dependent RNA polymerase 1 regulate mRNAs in the basal fungus Mucor circinelloides
    Francisco Esteban Nicolas
    School of Biological Sciences, University of East Anglia, Norwich, NR4 7TJ, UK
    Nucleic Acids Res 38:5535-41. 2010
  3. ncbi Biochemical events leading to the diversion of carbon into storage lipids in the oleaginous fungi Mucor circinelloides and Mortierella alpina
    J P Wynn
    Centre for Advanced Lipid Research, Department of Biological Sciences, University of Hull, Hull HU6 7RX, UK
    Microbiology 147:2857-64. 2001
  4. pmc A single dicer gene is required for efficient gene silencing associated with two classes of small antisense RNAs in Mucor circinelloides
    Juan P de Haro
    Departamento de Genética y Microbiología, Facultad de Biologia, Universidad de Murcia, 30100 Murcia, Spain
    Eukaryot Cell 8:1486-97. 2009
  5. ncbi Overexpression of acetyl-CoA carboxylase gene of Mucor rouxii enhanced fatty acid content in Hansenula polymorpha
    Rawisara Ruenwai
    School of Bioresources and Technology, King Mongkut s University of Technology Thonburi, Bangkhuntien, Bangkok, 10150, Thailand
    Mol Biotechnol 42:327-32. 2009
  6. pmc Two classes of small antisense RNAs in fungal RNA silencing triggered by non-integrative transgenes
    Francisco E Nicolas
    Departamento de Genética y Microbiología, Facultad de Biologia, Universidad de Murcia, 30071 Murcia, Spain
    EMBO J 22:3983-91. 2003
  7. doi Effects of different growth forms of Mucor indicus on cultivation on dilute-acid lignocellulosic hydrolyzate, inhibitor tolerance, and cell wall composition
    Patrik R Lennartsson
    School of Engineering, University of Borås, 501 90 Borås, Sweden Department of Chemical and Biological Engineering, Chalmers University of Technology, 41296 Goteborg, Sweden
    J Biotechnol 143:255-61. 2009
  8. pmc A subunit of protein kinase a regulates growth and differentiation in the fungus Mucor circinelloides
    J Ocampo
    Departamento de Genética y Microbiología, Facultad de Biologia, Universidad de Murcia, 30071 Murcia, Spain
    Eukaryot Cell 8:933-44. 2009
  9. doi Transcriptional activation increases RNA silencing efficiency and stability in the fungus Mucor circinelloides
    Francisco E Nicolas
    Departamento de Genética y Microbiología Unidad asociada al IQFR CSIC, Facultad de Biologia, Universidad de Murcia, 30071 Murcia, Spain
    J Biotechnol 142:123-6. 2009
  10. ncbi cigA, a light-inducible gene involved in vegetative growth in Mucor circinelloides is regulated by the carotenogenic repressor crgA
    María D Quiles-Rosillo
    Departamento de Genética y Microbiología, Facultad de Biologia, Universidad de Murcia, 30071, Murcia, Spain
    Fungal Genet Biol 38:122-32. 2003

Research Grants

Detail Information

Publications208 found, 100 shown here

  1. doi Two distinct RNA-dependent RNA polymerases are required for initiation and amplification of RNA silencing in the basal fungus Mucor circinelloides
    Silvia Calo
    Departamento de Genética y Microbiología, Facultad de Biologia, Universidad de Murcia, 30100 Murcia, Spain
    Mol Microbiol 83:379-94. 2012
    ..RNA silencing in the zygomycete Mucor circinelloides exhibits uncommon features, such as induction by self-replicative sense transgenes and an ..
  2. pmc Endogenous short RNAs generated by Dicer 2 and RNA-dependent RNA polymerase 1 regulate mRNAs in the basal fungus Mucor circinelloides
    Francisco Esteban Nicolas
    School of Biological Sciences, University of East Anglia, Norwich, NR4 7TJ, UK
    Nucleic Acids Res 38:5535-41. 2010
    ..Here, we show that the basal fungus Mucor circinelloides produces new classes of esRNAs that map to exons and regulate the expression of many protein coding ..
  3. ncbi Biochemical events leading to the diversion of carbon into storage lipids in the oleaginous fungi Mucor circinelloides and Mortierella alpina
    J P Wynn
    Centre for Advanced Lipid Research, Department of Biological Sciences, University of Hull, Hull HU6 7RX, UK
    Microbiology 147:2857-64. 2001
    The biochemical events associated with the onset of lipid accumulation in Mucor circinelloides and Mortierella alpina, under conditions of nitrogen-limited growth, have been elucidated; they differ in key aspects from those described in ..
  4. pmc A single dicer gene is required for efficient gene silencing associated with two classes of small antisense RNAs in Mucor circinelloides
    Juan P de Haro
    Departamento de Genética y Microbiología, Facultad de Biologia, Universidad de Murcia, 30100 Murcia, Spain
    Eukaryot Cell 8:1486-97. 2009
    RNA silencing in the zygomycete Mucor circinelloides exhibits uncommon features, such as induction by self-replicative sense transgenes and the accumulation of two size classes of antisense small interfering RNAs (siRNAs)...
  5. ncbi Overexpression of acetyl-CoA carboxylase gene of Mucor rouxii enhanced fatty acid content in Hansenula polymorpha
    Rawisara Ruenwai
    School of Bioresources and Technology, King Mongkut s University of Technology Thonburi, Bangkhuntien, Bangkok, 10150, Thailand
    Mol Biotechnol 42:327-32. 2009
    ..In this work, a gene coding for acetyl-CoA carboxylase (ACC) was isolated from an oleaginous fungus, Mucor rouxii...
  6. pmc Two classes of small antisense RNAs in fungal RNA silencing triggered by non-integrative transgenes
    Francisco E Nicolas
    Departamento de Genética y Microbiología, Facultad de Biologia, Universidad de Murcia, 30071 Murcia, Spain
    EMBO J 22:3983-91. 2003
    Transformation of Mucor circinelloides with self-replicative plasmids containing a wild-type copy of the carotenogenic gene carB causes silencing of the carB function in 3% of transformants...
  7. doi Effects of different growth forms of Mucor indicus on cultivation on dilute-acid lignocellulosic hydrolyzate, inhibitor tolerance, and cell wall composition
    Patrik R Lennartsson
    School of Engineering, University of Borås, 501 90 Borås, Sweden Department of Chemical and Biological Engineering, Chalmers University of Technology, 41296 Goteborg, Sweden
    J Biotechnol 143:255-61. 2009
    The dimorphic fungus Mucor indicus was grown in different forms classified as purely filamentous, mostly filamentous, mostly yeast-like and purely yeast-like, and the relationship between morphology and metabolite production, inhibitor ..
  8. pmc A subunit of protein kinase a regulates growth and differentiation in the fungus Mucor circinelloides
    J Ocampo
    Departamento de Genética y Microbiología, Facultad de Biologia, Universidad de Murcia, 30071 Murcia, Spain
    Eukaryot Cell 8:933-44. 2009
    ..To determine whether PKA plays a similar function in zygomycete fungi, a mutant of Mucor circinelloides was generated that lacks pkaR1, one of the regulatory subunits of PKA...
  9. doi Transcriptional activation increases RNA silencing efficiency and stability in the fungus Mucor circinelloides
    Francisco E Nicolas
    Departamento de Genética y Microbiología Unidad asociada al IQFR CSIC, Facultad de Biologia, Universidad de Murcia, 30071 Murcia, Spain
    J Biotechnol 142:123-6. 2009
    ..of the RNA silencing mechanism was investigated after transcriptional activation of the transgene carB in Mucor circinelloides...
  10. ncbi cigA, a light-inducible gene involved in vegetative growth in Mucor circinelloides is regulated by the carotenogenic repressor crgA
    María D Quiles-Rosillo
    Departamento de Genética y Microbiología, Facultad de Biologia, Universidad de Murcia, 30071, Murcia, Spain
    Fungal Genet Biol 38:122-32. 2003
    ..target genes controlled by crgA, a negative regulator of the light-inducible carotenogenesis in the fungus Mucor circinelloides...
  11. doi Hepatic and renal artery rupture due to Aspergillus and Mucor mixed infection after combined liver and kidney transplantation: a case report
    H X Zhan
    Department of Hepatobiliary Surgery, First Affiliated Hospital, Medical College, Xi an Jiaotong University, Xi an, People s Republic of China
    Transplant Proc 40:1771-3. 2008
    ..The incidence of Aspergillus or Mucor infection is low compared with Candida species...
  12. doi A RING-finger photocarotenogenic repressor involved in asexual sporulation in Mucor circinelloides
    Francisco E Nicolas
    Departamento de Genética y Microbiología, Facultad de Biologia, Universidad de Murcia Murcia, Spain
    FEMS Microbiol Lett 280:81-8. 2008
    b>Mucor circinelloides responds to blue light by activating the biosynthesis of carotenoids and bending its sporangiophores towards the light source...
  13. doi The mating-related loci sexM and sexP of the zygomycetous fungus Mucor mucedo and their transcriptional regulation by trisporoid pheromones
    Jana Wetzel
    Institute of General Microbiology and Microbe Genetics, Friedrich Schiller University Jena, Neugasse 24, D 07743 Jena, Germany
    Microbiology 158:1016-23. 2012
    ..primers derived from the amino acid sequence of the RNA helicase to sequence a fragment of this gene from Mucor mucedo...
  14. ncbi A gene coding for ornithine decarboxylase (odcA) is differentially expressed during the Mucor circinelloides yeast-to-hypha transition
    José L Blasco
    Departamento de Microbiologia y Genetica, Universidad de Salamanca, Spain
    Res Microbiol 153:155-64. 2002
    The differential display technique was used to identify genes from Mucor circinelloides involved in the yeast-to-hypha transition...
  15. doi Degradation pathway of pentachlorophenol by Mucor plumbeus involves phase II conjugation and oxidation-reduction reactions
    Mariana B Carvalho
    Instituto de Tecnologia Quimica e Biologica, Universidade Nova de Lisboa, Oeiras, Portugal
    J Hazard Mater 198:133-42. 2011
    ..Mucorales from the Zygomycota phylum are often observed to be competitive in field conditions and Mucor plumbeus, in particular, can efficiently deplete PCP from media...
  16. ncbi Aleuria aurantia lectin exhibits antifungal activity against Mucor racemosus
    Koh Amano
    Graduate School of Science and Technology, Chiba University, Matsudo, Chiba, Japan
    Biosci Biotechnol Biochem 76:967-70. 2012
    ..To investigate this, we analyzed the interaction between AAL and, a zygomycete fungus Mucor racemosus, which is assumed to contain fucose in its cell wall. AAL specifically bound to the hyphae of M...
  17. pmc Sporangiospore size dimorphism is linked to virulence of Mucor circinelloides
    Charles H Li
    Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America
    PLoS Pathog 7:e1002086. 2011
    b>Mucor circinelloides is a zygomycete fungus and an emerging opportunistic pathogen in immunocompromised patients, especially transplant recipients and in some cases otherwise healthy individuals...
  18. ncbi Protein kinase A is involved in the control of morphology and branching during aerobic growth of Mucor circinelloides
    Tina Lübbehüsen
    Center for Process Biotechnology, Technical University of Denmark, Building 223, DK 2800 Lyngby, Denmark
    Microbiology 150:143-50. 2004
    The cAMP signal transduction pathway controls many processes in fungi. The Mucor circinelloides pkaR and pkaC genes, encoding the regulatory (PKAR) and catalytic (PKAC) subunit of the cAMP-dependent protein kinase A (PKA), have been ..
  19. pmc Protein kinase A regulatory subunit isoforms regulate growth and differentiation in Mucor circinelloides: essential role of PKAR4
    J Ocampo
    Departamento de Quimica Biologica, Universidad de Buenos Aires, Ciudad Universitaria, Buenos Aires, Argentina
    Eukaryot Cell 11:989-1002. 2012
    ..kinase A (PKA) signaling pathway plays a role in regulating growth and differentiation in the dimorphic fungus Mucor circinelloides. PKA holoenzyme is comprised of two catalytic (C) and two regulatory (R) subunits. In M...
  20. ncbi Fed-batch cultivation of Mucor indicus in dilute-acid lignocellulosic hydrolyzate for ethanol production
    Keikhosro Karimi
    Department of Chemical Engineering and Environmental Science, Chalmers University of Technology, 412 96, Goteborg, Sweden
    Biotechnol Lett 27:1395-400. 2005
    b>Mucor indicus fermented dilute-acid lignocellulosic hydrolyzates to ethanol in fed-batch cultivation with complete hexose utilization and partial uptake of xylose. The fungus was tolerant to the inhibitors present in the hydrolyzates...
  21. ncbi Inactivation of Mucor plumbeus by the combined actions of chitinase and high hydrostatic pressure
    M Fenice
    Dipartimento di Agrobiologia e Agrochimica, University of Tuscia, Viterbo, Italy
    Int J Food Microbiol 52:109-13. 1999
    ..and/or fungal chitinase in order to study the inhibition of germination and growth of the food spoiling mold Mucor plumbeus. Total fungal inhibition was obtained either at 4...
  22. ncbi Molecular cloning of Mucor hiemalis endo-beta-N-acetylglucosaminidase and some properties of the recombinant enzyme
    Kiyotaka Fujita
    Division of Integrated Life Science, Graduate School of Biostudies, Kyoto University, Kyoto 606 8502, Japan
    Arch Biochem Biophys 432:41-9. 2004
    Endo-M, endo-beta-N-acetylglucosaminidase from Mucor hiemalis, is known as a useful enzyme for the synthesis of neoglycopeptides due to its transglycosylation activity...
  23. doi Biotransformation using Mucor rouxii for the production of oleanolic acid derivatives and their antimicrobial activity against oral pathogens
    Clarissa S Capel
    Faculdade de Ciencias Farmaceuticas de Ribeirao Preto, Universidade de Sao Paulo, Avenida do Café, S N, Ribeirao Preto, SP, 14040 903, Brazil
    J Ind Microbiol Biotechnol 38:1493-8. 2011
    The goal of this study is to produce oleanolic acid derivatives by biotransformation process using Mucor rouxii and evaluate their antimicrobial activity against oral pathogens...
  24. ncbi Transformation of Mucor miehei results in plasmid deletion and phenotypic instability
    Aurelia Monfort
    Instituto de Agroquimica y Tecnologia de Alimentos, Consejo Superior de Investigaciones Cientificas, Apartado de Correos 73, E 46100 Burjassot, Valencia, Spain
    FEMS Microbiol Lett 224:101-6. 2003
    b>Mucor miehei transformants resistant to geneticin have been obtained by treatment of protoplasts with different plasmids and by Agrobacterium-mediated DNA transfer...
  25. doi Morphological changes of the filamentous fungus Mucor mucedo and inhibition of chitin synthase activity induced by anethole
    Masahiro Yutani
    Graduate School of Science, Osaka City University, 3 3 138 Sugimoto, Sumiyoshi ku, Osaka 558 8585, Japan
    Phytother Res 25:1707-13. 2011
    ..Anethole demonstrated antifungal activity against the filamentous fungus, Mucor mucedo IFO 7684, accompanied by hyphal morphological changes such as swollen hyphae at the tips...
  26. ncbi Malic enzyme: the controlling activity for lipid production? Overexpression of malic enzyme in Mucor circinelloides leads to a 2.5-fold increase in lipid accumulation
    Ying Zhang
    Department of Biological Sciences, University of Hull, Hull HU6 7RX, UK
    Microbiology 153:2013-25. 2007
    ..The genes encoding the isoform of ME involved in fatty acid synthesis were identified in Mucor circinelloides and Mortierella alpina, two commercially useful oil-producing fungi, using degenerate primers...
  27. doi Orbital and cranial nerve presentations and sequelae are hallmarks of invasive fungal sinusitis caused by Mucor in contrast to Aspergillus
    Avani P Ingley
    Department of Otolaryngology, Emory University School of Medicine, Atlanta, Georgia
    Am J Rhinol 22:155-8. 2008
    ..Outcome differences have been found in patients with Mucor and Aspergillus...
  28. ncbi Cloning and characterization of a gene encoding a malic enzyme involved in anaerobic growth in Mucor circinelloides
    Yonghua Li
    Centre for Lipid Research, University of Hull, Cottingham Road, Hull HU6 7RX, UK
    Mycol Res 109:461-8. 2005
    A 3193 bp contiguous sequence has been cloned from the oleaginous fungus Mucor circinelloides, that contains a full-length gene encoding a putative NADP+: dependent malic enzyme (EC. 1.1.1.40)...
  29. ncbi Production of phytase by Mucor racemosus in solid-state fermentation
    Barbara Bogar
    Department of Agricultural Chemical Technology, Budapest University of Technology and Economics, 1111 Budapest, Gellert ter 4, Hungary
    Biotechnol Prog 19:312-9. 2003
    Phytase production was studied by three Mucor and eight Rhizopus strains by solid-state fermentation (SSF) on three commonly used natural feed ingredients (canola meal, coconut oil cake, wheat bran)...
  30. ncbi A multicopy vector system for genetic studies in Mucor circinelloides and other zygomycetes
    K F Appel
    Department of Fungal Biotechnology, Biotechnological Institute, Kogle Alle 2, DK 2970, Hørsholm, Denmark
    Mol Genet Genomics 271:595-602. 2004
    Transformation of Mucor circinelloides is routinely achieved by using a plasmid containing the wild-type leuA gene to complement the leucine requirement of an auxotrophic host strain...
  31. ncbi Complementary mating types of Mucor circinelloides show electrophoretic karyotype heterogeneity
    J M Diaz-Minguez
    Departamento de Microbiologia y Genetica, Universidad de Salamanca, Spain
    Curr Genet 36:383-9. 1999
    Electrophoretic karyotypes of ten strains of Mucor circinelloides f. lusitanicus were generated by contour-clamped homogeneous electric field (CHEF) gel-electrophoresis...
  32. ncbi Mutants defective in a Mucor circinelloides dicer-like gene are not compromised in siRNA silencing but display developmental defects
    Francisco E Nicolas
    Departamento de Genética y Microbiología, Facultad de Biologia, Universidad de Murcia 30071 Murcia, Spain
    Fungal Genet Biol 44:504-16. 2007
    ..We have isolated a dicer-like gene (dcl-1) of Mucor circinelloides, the first gene of this family to be identified in zygomycetes...
  33. ncbi Morphology and physiology of the dimorphic fungus Mucor circinelloides (syn. M. racemosus) during anaerobic growth
    Tina L Lübbehüsen
    Center for Process Biotechnology, Building 223, BioCentrum DTU, Technical University of Denmark, DK 2800 Kgs Lyngby, Denmark
    Mycol Res 107:223-30. 2003
    The dimorphic Mucor circinelloides requires an anaerobic atmosphere and the presence of 30% CO2 to grow as a multipolar budding yeast, otherwise hyphal growth predominates...
  34. doi High reliability transformation of the basal fungus Mucor circinelloides by electroporation
    Adrián Gutiérrez
    Departamento de Genética y Microbiología Unidad asociada al IQFR CSIC, Facultad de Biologia, Universidad de Murcia, 30071 Murcia, Spain
    J Microbiol Methods 84:442-6. 2011
    Molecular approaches to study the biology of the zygomycete Mucor circinelloides depend mainly on the existence of a polyethylene glycol-based transformation method, which is one of the most efficient in zygomycete fungi...
  35. ncbi Comparison of phytase production on wheat bran and oilcakes in solid-state fermentation by Mucor racemosus
    Krishnan Roopesh
    Biotechnology Division, Regional Research Laboratory, CSIR, Trivandrum 695 019, India
    Bioresour Technol 97:506-11. 2006
    ..made for phytase production using wheat bran (WB) and oilcakes as substrates in solid-state fermentation (SSF) by Mucor racemosus NRRL 1994. WB was also used as mixed substrate with oil cakes...
  36. pmc Alternative splicing produces two endoglucanases with one or two carbohydrate-binding modules in Mucor circinelloides
    Yuko Baba
    Food and Health R and D Laboratories, Meiji Seika Kaisha, Ltd, 5 3 1, Chiyoda, Sakado shi, Saitama 350 0289, Japan
    J Bacteriol 187:3045-51. 2005
    ..In this study, two cDNAs homologous to the rce1 gene, designated the mce1 and mce2 cDNAs, were cloned from Mucor circinelloides, a member of the subdivision Zygomycota...
  37. ncbi Mucor rouxii Rho1 protein; characterization and possible role in polarized growth
    Silvia Argimon
    Departamento de Quimica Biologica, Facultad de Ciencias Exactas y Naturales, Ciudad Universitaria, Pabellon 2, Piso 4, 1428, Buenos Aires, Argentina
    Antonie Van Leeuwenhoek 91:237-51. 2007
    We have previously shown that protein kinase A of the medically important zygomycete Mucor rouxii participates in fungal morphology through cytoskeletal organization...
  38. ncbi A pre-genetic study of the isoforms of malic enzyme associated with lipid accumulation in Mucor circinelloides
    Y Song
    Centre for Advanced Lipid Research, Department of Biological Sciences, University of Hull, Hull HU6 7RX, UK
    Microbiology 147:1507-15. 2001
    The oleaginous fungus Mucor circinelloides possesses at least six isoforms of malic enzyme (EC 1.1.1.40), a key lipogenic enzyme in filamentous fungi...
  39. pmc In vivo activity of posaconazole against Mucor spp. in an immunosuppressed-mouse model
    Qiu N Sun
    Division of Infectious Disease, Department of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
    Antimicrob Agents Chemother 46:2310-2. 2002
    ..The in vitro MICs of posaconazole and itraconazole for the strains of Mucor spp. used in this study ranged from 0.125 to 8 microg/ml and 0.25 to 8 microg/ml, respectively...
  40. ncbi Fungemia and cutaneous zygomycosis due to Mucor circinelloides in an intensive care unit patient: case report and review of literature
    Murat Dizbay
    Department of Infectious Diseases, Gazi University School of Medicine, Ankara, Turkey
    Jpn J Infect Dis 62:146-8. 2009
    b>Mucor spp. are rarely pathogenic in healthy adults, but can cause fatal infections in patients with immuosuppression and diabetes mellitus. Documented mucor fungemia is a very rare condition in the literature...
  41. ncbi Substrate specificity and preference of Delta6-desaturase of Mucor rouxii
    Sutthicha Na-Ranong
    School of Bioresources and Technology, King Mongkut s University of Technology Thonburi, Bangkuntien, Bangkok, Thailand
    FEBS Lett 579:2744-8. 2005
    ..expression in Saccharomyces cerevisiae, substrate specificity and preference of Delta(6)-desaturase of Mucor rouxii...
  42. ncbi Cloning of glyceraldehyde-3-phosphate dehydrogenase-encoding genes in Mucor circinelloides (Syn. racemosus) and use of the gpd1 promoter for recombinant protein production
    Anne Mette Wolff
    Department of Fungal Biotechnology, Biotechnological Institute, Kogle Alle 2, Hørsholm, DK 2970, Denmark
    Fungal Genet Biol 35:21-9. 2002
    ..gpd2, and gpd3) encoding glyceraldehyde-3-phosphate dehydrogenase were isolated from the dimorphic zygomycete Mucor circinelloides by PCR using degenerated primers...
  43. ncbi Physical and chemical adsorption of Mucor javanicus lipase on SBA-15 mesoporous silica. Synthesis, structural characterization, and activity performance
    Andrea Salis
    Department of Chemical Sciences, University of Cagliari, S S 554 Bivio Sestu 09042 Monserrato CA, Italy
    Langmuir 21:5511-6. 2005
    ..Immobilization by physical adsorption of a commercial lipase preparation from Mucor javanicus was performed at different pH values (pH 5-8)...
  44. ncbi Mutants of Mucor hiemalis endo-beta-N-acetylglucosaminidase show enhanced transglycosylation and glycosynthase-like activities
    Midori Umekawa
    Division of Integrated Life Science, Graduate School of Biostudies, Kyoto University, Kitashirakawa, Sakyo ku, Kyoto 606 8502, Japan
    J Biol Chem 283:4469-79. 2008
    Endo-beta-N-acetylglucosaminidase from Mucor hiemalis (Endo-M), a family 85 glycoside hydrolase, acts on the beta1,4 linkage of N,N'-diacetylchitobiose moiety in the N-linked glycans of glycoproteins and catalyzes not only the hydrolysis ..
  45. ncbi Heterologous expression of astaxanthin biosynthesis genes in Mucor circinelloides
    Tamas Papp
    Department of Microbiology, Faculty of Sciences, University of Szeged, P O Box 533, 6701, Szeged, Hungary
    Appl Microbiol Biotechnol 69:526-31. 2006
    Most Mucor species accumulate beta-carotene as the main carotenoid. The crtW and crtZ astaxanthin biosynthesis genes from Agrobacterium aurantiacum were placed under the control of Mucor circinelloides expression signals...
  46. ncbi Distinct white collar-1 genes control specific light responses in Mucor circinelloides
    Fatima Silva
    Departamento de Genética y Microbiología, Facultad de Biologia, Universidad de Murcia, 30071 Murcia, Spain
    Mol Microbiol 61:1023-37. 2006
    ..The best-known light response in the fungus Mucor circinelloides is the biosynthesis of beta-carotene. Here, we show that M...
  47. ncbi Purification and characterisation of an acid phosphatase with phytase activity from Mucor hiemalis Wehmer
    A Boyce
    Department of Chemical and Environmental Sciences, University of Limerick, Limerick City, Ireland
    J Biotechnol 132:82-7. 2007
    An acid phosphatase with phytase activity, produced by Mucor hiemalis Wehmer, was purified to homogeneity by a combination of anion exchange, gel filtration and hydrophobic interaction chromatography...
  48. ncbi Newly discovered neutral glycosphingolipids in aureobasidin A-resistant zygomycetes: Identification of a novel family of Gala-series glycolipids with core Gal alpha 1-6Gal beta 1-6Gal beta sequences
    Kazuhiro Aoki
    Graduate School of Biostudies, Kyoto University, Oiwake cho, Kitashirakawa, Sakyo ku, Kyoto 606 8502, Japan
    J Biol Chem 279:32028-34. 2004
    ..A novel family of neutral glycosphingolipids (GSLs) was found in these fungi and isolated from Mucor hiemalis, which is a typical Zygomycetes species...
  49. ncbi Molecular analysis of an NAD-dependent alcohol dehydrogenase from the zygomycete Mucor circinelloides
    R A Rangel-Porras
    Instituto de Investigación en Biología Experimental Facultad de Química, Universidad de Guanajuato, Noria Alta s n Apartado Postal 187, 36000, Guanajuato, Mexico
    Mol Genet Genomics 274:354-63. 2005
    ..was detected mainly in the cytosol of aerobically cultured mycelium and in anaerobically grown yeast cells of Mucor circinelloides. ADH levels were about 2...
  50. ncbi Phase II metabolites of etofesalamide in filamentous fungi
    Hai Hua Huang
    Department of Pharmaceutical Microbiology, Shenyang Pharmaceutical University, Shenyang 110016, China
    Acta Pharmacol Sin 26:893-6. 2005
    ..To study phase II metabolites of etofesalamide in filamentous fungi...
  51. ncbi Predictors of pulmonary zygomycosis versus invasive pulmonary aspergillosis in patients with cancer
    Georgios Chamilos
    Department of Infectious Diseases, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Clin Infect Dis 41:60-6. 2005
    ..Most cases of PZ in such patients develop as breakthrough infections if treatment with antifungal agents effective against Aspergillus species is administered. However, clinical criteria to differentiate PZ from IPA are lacking...
  52. ncbi Isolation, identification and antifungal susceptibility of lemon pathogenic and non pathogenic fungi
    María Cristina Maldonado
    Instituto de Biotecnologia, Facultad de Bioquimica, Quimica y Farmacia, Universidad Nacional de Tucuman, Tucuman, Argentina
    Rev Iberoam Micol 22:57-9. 2005
    ..flavus, Aspergillus clavatus, Geotrichum candidum, Rhizopus sp, Penicillium sp, Penicillium digitatum and Mucor sp were studied. All the tested strains were resistant to thiabendazole...
  53. pmc Posaconazole enhances the activity of amphotericin B against hyphae of zygomycetes in vitro
    Susanne Perkhofer
    Department of Hygiene, Microbiology and Social Medicine, Medical University Innsbruck, Fritz Pregl Str 3, A 6020 Innsbruck, Austria
    Antimicrob Agents Chemother 52:2636-8. 2008
    ..The combination of posaconazole with amphotericin B was found to be significantly more synergistic (40%) against hyphae (P < 0.05) than against conidia (10%). Antagonism was not observed...
  54. ncbi Evidence for selective hydrolysis of aliphatic copolyesters induced by lipase catalysis
    Paola Rizzarelli
    Istituto di Chimica e Tecnologia dei Polimeri, Consiglio Nazionale delle Ricerche, Viale A Doria 6, 95125 Catania, Italy
    Biomacromolecules 5:433-44. 2004
    ..P(BS-co-BA), with different composition, were synthesized and subjected to enzymatic hydrolysis by Lipase from Mucor miehei or from Rhizopus arrhizus...
  55. ncbi Antifungal activity of essential oils against filamentous fungi determined by broth microdilution and vapour contact methods
    V Tullio
    Department of Public Health and Microbiology, University of Turin, Turin, Italy
    J Appl Microbiol 102:1544-50. 2007
    ..The in vitro activity of some essential oils (EO) (thyme red, fennel, clove, pine, sage, lemon balm and lavender) against clinical and environmental fungal strains was determined...
  56. ncbi Study of lipase-catalyzed hydrolysis of some monoterpene esters
    T Chatterjee
    Department of Chemical Technology, University Colleges of Science and Technology, University of Calcutta, India
    Can J Microbiol 47:397-403. 2001
    ..geranyl, and terpenyl acetates by commercially available lipases of Candida rugosa, Rhizopus arrhizus, and Mucor miehei are presented...
  57. ncbi Stereoselectivity of the generation of 3-mercaptohexanal and 3-mercaptohexanol by lipase-catalyzed hydrolysis of 3-acetylthioesters
    Hidehiko Wakabayashi
    Lehrstuhl fur Allgemeine Lebensmitteltechnologie, Technische Universitat Munchen, Am Forum 2, D 85350 Freising Weihenstephan, Germany
    J Agric Food Chem 51:4349-55. 2003
    ..The sulfur-containing compounds investigated possess attractive odor properties, and only one of the enantiomers exhibits the pleasant citrus type note...
  58. ncbi Gas-phase enzymatic esterification on immobilized lipases in MCM-41 molecular sieves
    Emerson Luis Pires
    Department of Chemical Processes, School of Chemical Engineering, State University of Campinas, SP, Brazil
    Appl Biochem Biotechnol 98:963-76. 2002
    ....
  59. ncbi Cerebral zygomycosis
    C Sundaram
    Department of Pathology, Nizam s Institute of Medical Sciences, Punjagutta, Hyderabad, India
    Mycoses 48:396-407. 2005
    ..Of these, ten were culture proven (Rhizopus oryzae in eight and Mucor in two); 30 were diagnosed as probable and 16 were diagnosed possible; mixed infections were seen in three ..
  60. ncbi Contemporary treatment and outcomes of zygomycosis in a non-oncologic tertiary care center
    Charles R Sims
    Laboratory of Mycology Research, Division of Infectious Diseases, University of Texas Houston Medical School, Houston, Texas 77030, USA
    Arch Med Res 38:90-3. 2007
    ..Zygomycosis is an emerging mycosis of increasing relevance. Limited data exist for outcomes with contemporary therapies...
  61. pmc Bacterial endosymbiosis is widely present among zygomycetes but does not contribute to the pathogenesis of mucormycosis
    Ashraf S Ibrahim
    Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, CA 90502, USA
    J Infect Dis 198:1083-90. 2008
    ....
  62. ncbi Native-like tertiary structure in the Mucor miehei lipase molten globule state obtained at low pH
    Sadaf Fatima
    Interdisciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh, India
    IUBMB Life 59:179-86. 2007
    Studies on the acid-induced denaturation of Mucor miehei lipase (E.C. 3.1.1...
  63. ncbi Improvement in extraction and catalytic activity of Mucor javanicus lipase by modification of AOT reverse micelle
    Mahabubur Rahman Talukder
    Institute of Chemical and Engineering Sciences, Singapore, Singapore
    Biotechnol J 2:1369-74. 2007
    ..The modified AOT reverse micellar system was used to extract Mucor javanicus lipase from the aqueous phase to the reverse micellar phase...
  64. ncbi Microbial transformations of alpha-santonin
    Athar Ata
    Department of Chemistry, The University of Winnipeg, 515 Portage Avenue, Winnipeg, Manitoba, Canada R3B 2E9
    Z Naturforsch C 59:209-14. 2004
    Fungal biotransformations of alpha-santonin (1) were conducted with Mucor plumbeus (ATCC 4740), Cunninghamella bainieri (ATCC 9244), Cunninghamella echinulata (ATCC 9245), Curvularia lunata (ATCC 12017) and Rhizopus stolonifer (ATCC ..
  65. ncbi Enzymatic synthesis of phosphocarnitine, phosphogabob and fosfomycin
    Ke Wang
    Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai, 200032, China
    Org Biomol Chem 1:3564-9. 2003
    ..obtained from easily available diethyl 3-chloro-2-oxopropanephosphonates, followed by subsequent reduction, Mucor miehei lipase (IM) mediated resolution, amination and dealkylation...
  66. ncbi Highly regioselective enzymatic synthesis of polymerizable derivatives of methyl shikimate
    Chao Li
    Department of Chemistry, Key Laboratory of Green Chemistry and Technology Ministry of Education, Sichuan University, Chengdu 610064, PR China
    Bioorg Med Chem Lett 17:6687-90. 2007
    ..Lipase acrylic resin from Candida antarctica (CAL-B) and immobilized lipase from Mucor miehei (MML) showed high regioselectivity toward the secondary hydroxyl of methyl shikimate, which presents three ..
  67. ncbi Effect of media composition and in vitro activity of posaconazole, caspofungin and voriconazole against zygomycetes
    Cristina Gil-Lamaignere
    Department of Paediatrics III, Paediatric Pulmonology and Infectious Diseases, University of Heidelberg, Im Neuenheimer Feld 153, D 69120 Heidelberg, Germany
    J Antimicrob Chemother 55:1016-9. 2005
    ..The effect of different media and composition on the in vitro activity of posaconazole, caspofungin and voriconazole against 59 zygomycetes species was determined...
  68. ncbi The fungal profile of otomycosis patients in Ilorin, Nigeria
    C Nwabuisi
    Department of Medical Microbiology, Faculty of Health Sciences, University of Ilorin, P.M.B. 1515, Ilorin, Kwara State
    Niger J Med 10:124-6. 2001
    ..76(54%) were positive for at least one organism. The isolates included: Aspergillus (63.2%), Candida (35.5%), and Mucor (0.7%). Further analysis showed that Candida species comprised C. albicans (18.4%), C. tropicalis (10.5%), and C...
  69. ncbi Fungi, aflatoxins, fumonisin Bl and zearalenone contaminating sorghum-based traditional malt, wort and beer in Botswana
    David O Nkwe
    Department of Biological Sciences, University of Botswana, Gaborone
    Mycopathologia 160:177-86. 2005
    ..Rhizopus, Fusarium, Mucor, and Aspergillus were the most common genera isolated...
  70. doi Semisynthetic and biotransformation studies of (1S,2E,4S,6R,7E,11E)-2,7,11-cembratriene-4,6-diol
    Khalid A El Sayed
    Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe 71209, USA
    J Nat Prod 71:117-22. 2008
    ..Biotransformation of 1 using Mucor ramannianus ATCC 9628 and Cunninghamella elegans ATCC 7929 afforded the known 10 S,11 S-epoxy analogue of 1 (4) as ..
  71. doi Microbial transformation of isosteviol and bioactivities against the glucocorticoid/androgen response elements
    Shwu Fen Chang
    Department of Medicinal Chemistry, College of Pharmacy, Taipei Medical University, Taiwan, Republic of China
    J Nat Prod 71:87-92. 2008
    Preparative-scale fermentation of isosteviol ( ent-16-oxobeyeran-19-oic acid) (1) with Mucor recurvatus MR 36, Absidia pseudocylindrospora ATCC 24169, and Aspergillus niger BCRC 32720 afforded nine known metabolites ( 2, 3, 5-10, and 14) ..
  72. ncbi Biotransformation of 20(S)-protopanaxatriol by Mucor spinosus and the cytotoxic structure activity relationships of the transformed products
    Jie Zhang
    Division of Pharmacognostical Biotechnology, School of Pharmaceutical Sciences, Peking University, Beijing 100083, China
    Phytochemistry 68:2523-30. 2007
    Biotransformation of 20(S)-protopanaxatriol (1) by the fungus Mucor spinosus AS 3.3450 gave 10 metabolites (2-10), of which 2-5 were previously known...
  73. pmc Development and application of an assay for uranyl complexation by fungal metabolites, including siderophores
    Joanna C Renshaw
    Centre for Radiochemistry Research, Department of Chemistry, The University of Manchester, Manchester M13 9PT, United Kingdom
    Appl Environ Microbiol 69:3600-6. 2003
    ..Three isolates were selected for further study and were identified as two Pencillium species and a Mucor species...
  74. ncbi Microbial hydroxylation of bufalin by Cunninghamella blakesleana and Mucor spinosus
    Min Ye
    The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xueyuan Road 38, Beijing 100083, People s Republic of China
    J Nat Prod 68:626-8. 2005
    ..Two minor products were isolated from the culture broth of Mucor spinosus and were identified as 7beta,15alpha-dihydroxybufalin (6) and 5beta,7beta-dihydroxybufalin (7), ..
  75. ncbi Microbial transformation of dehydrocostuslactone by Mucor polymorphosporus
    X C Ma
    The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China
    J Asian Nat Prod Res 8:713-8. 2006
    Biotransformation of dehydrocostuslactone (1) by Mucor polymorphosporus yielded four compounds, and their structures were identified as 11alpha,13-dihydrodehydrocostuslactone (2), 3alpha-hydroxy-11alpha,13-dihydrodehydrocostuslactone (3),..
  76. ncbi Microbial metabolism of steviol and steviol-16alpha,17-epoxide
    Li Ming Yang
    Department of Medicinal Chemistry, College of Pharmacy, Taipei Medical University, Taipei, Taiwan
    Phytochemistry 68:562-70. 2007
    ..Incubation of 2 with the microorganisms Bacillus megaterium ATCC 14581, Mucor recurvatus MR 36, and Aspergillus niger BCRC 32720 yielded one new metabolite, ent-7alpha,11beta,13-trihydroxykaur-..
  77. ncbi Structural determination of three new germacrane-type sesquiterpene alcohols from curdione by microbial transformation
    Xiao Chi Ma
    The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xueyuan Road 38, Beijing 100083, P R China
    Magn Reson Chem 45:90-2. 2007
    ..Among them, 4, 5 and 6 are new compounds...
  78. ncbi Microbial transformation of 20(S)-protopanaxatriol by Mucor spinosus
    Yin Tian
    The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xueyuan Road 38, Beijing 100083, People s Republic of China
    J Nat Prod 68:678-80. 2005
    Microbial biotransformation of 20(S)-protopanaxatriol (1) by the fungus Mucor spinosus (AS 3...
  79. ncbi The microbiological transformation of the diterpenes dehydroabietanol and teideadiol by Mucor plumbeus
    Braulio M Fraga
    Instituto de Productos Naturales y Agrobiologia, CSIC, Avda Astrofísico F Sánchez 3, La Laguna, 38206 Tenerife, Canary Islands, Spain
    Phytochemistry 63:663-8. 2003
    The microbiological transformation of dehydroabietanol (18-hydroxy-dehydroabietane) by Mucor plumbeus led to 2alpha,18-dihydroxy-abieta-8,11,13,15-tetraene, 2alpha,15-dihydroxy-dehydroabietanol, 2alpha-hydroxy-15-methoxy-dehydroabietanol,..
  80. ncbi Microbial transformation of the diterpene mulin-11,13-dien-20-oic acid by Mucor plumbeus
    Carlos Areche
    Department of Chemistry, Faculty of Sciences, University of Chile, Santiago, Chile
    Magn Reson Chem 46:765-8. 2008
    ..by microbial transformation of mulin-11,13-dien-20-oic acid (1), along with tyrosol (4) using liquid cultures of Mucor plumbeus. The latter compound has not been previously identified in the genus Mucor...
  81. ncbi Biotransformation of the diterpenes epicandicandiol and candicandiol by Mucor plumbeus
    Braulio M Fraga
    Instituto de Productos Naturales y Agrobiologia, PO Box 195, CSIC, 38206 La Laguna, Tenerife, Canary Islands, Spain
    J Nat Prod 66:327-31. 2003
    The microbiological transformation of the diterpene epicandicandiol (1) with Mucor plumbeus gave foliol (3), sideritriol (5), and 7beta,16alpha,17,18-tetrahydroxy-ent-kaurane (7), while the incubation of candicandiol (2) gave 7alpha,..
  82. ncbi A novel fungal prenyl diphosphate synthase in the dimorphic zygomycete Mucor circinelloides
    Antonio Velayos
    Area de Genetica, Departamento de Microbiologia y Genetica, Universidad de Salamanca, Edificio Departamental, Lab 301 2, Avenida Campo Charro s n, 37007 Salamanca, Spain
    Curr Genet 45:371-7. 2004
    Two Mucor circinelloides structural genes involved in isoprenoid biosynthesis were isolated and characterised. The isoA gene encodes a typical eukaryotic farnesyl diphosphate synthase (EC 2.5.1...
  83. ncbi Differential expression of desaturases and changes in fatty acid composition during sporangiospore germination and development in Mucor rouxii
    Sauvarat Khunyoshyeng
    School of Bioresources and Technology, King Mongkut s University of Technology Thonburi, Bangkok, Thailand
    Fungal Genet Biol 37:13-21. 2002
    ..gamma-linolenic acid (C18:3), constituted the majority in the total fatty acid content (44%) of sporangiospores of Mucor rouxii...
  84. ncbi Significance of fatty acid supplementation on profiles of cell growth, fatty acid, and gene expression of three desaturases in Mucor rouxii
    Sakda Khoomrung
    Pilot Plant Development and Training Institute, King Mongkut s University of Technology Thonburi, Bangkhuntien, Bangkok, Thailand
    Appl Microbiol Biotechnol 80:499-506. 2008
    ..of gamma-linolenic acid (GLA), a nutritionally important polyunsaturated fatty acid, were implemented in Mucor rouxii by supplementation with exogenous fatty acids...
  85. ncbi Characterization of the Mucor circinelloides life cycle by on-line image analysis
    T L Lübbehüsen
    Center for Process Biotechnology, BioCentrum DTU, Building 223, Technical University of Denmark, DK 2800 Lyngby, Denmark
    J Appl Microbiol 95:1152-60. 2003
    The life cycle of the dimorphic fungus Mucor circinelloides was studied in a temperature-controlled flow-through cell, which constitutes an ideal tool when following the development of individual cells, with a view to understanding the ..
  86. ncbi [Activity of NAD-dependent isocitrate dehydrogenase, isocitrate lyase, and malate dehydrogenase in Mucor circinelloides var. lusitanicus INMI under different modes of nitrogen supply]
    I S Mysiakina
    Mikrobiologiia 77:453-9. 2008
    ..and activity of the enzymes of the tricarboxylic acid cycle and the glyoxylate cycle were studied in the fungus Mucor circinelloides var...
  87. ncbi Post-harvest fungal quality of selected chewing sticks
    E Etebu
    Department of Biological Sciences, Plant Pathology Unit, Rivers State University of Science and Technology, Rivers State, Port Harcourt, Nigeria
    Oral Dis 9:95-8. 2003
    ..To study post-harvest fungal overgrowth on chewing sticks used for oral hygiene measures and role of disinfection...
  88. ncbi An unusual case of anaphylaxis. Mold in pancake mix
    A T Bennett
    Office of the Chief Medical Examiner Department of Pathology and Laboratory Medicine, Forensic Section Medical University of South Carolina, Charleston, USA
    Am J Forensic Med Pathol 22:292-5. 2001
    ..mix was analyzed and found to contain a total mold count of 700/g of mix as follows: Penicillium, Fusarium, Mucor, and Aspergillus...
  89. ncbi Investigation of fungal contamination in sheep and goat cheeses in southern Italy
    M T Montagna
    DIMIMP Sez Igiene, Universita degli Studi di Bari, Bari, Italy
    Mycopathologia 158:245-9. 2004
    ..9%), followed by Geotrichum spp. (7.3%), Aspergillus spp. (4.2%) and Mucor spp. (4.2%)...
  90. ncbi Lycopene over-accumulation by disruption of the negative regulator gene crgA in Mucor circinelloides
    Francisco E Nicolás-Molina
    Departamento de Genética y Microbiología, Facultad de Biologia, Universidad de Murcia, 30071, Murcia, Spain
    Appl Microbiol Biotechnol 78:131-7. 2008
    ..The crgA gene, a negative regulator of carotenogenesis, was disrupted in the Mucor circinelloides strain MU202, which lacks the lycopene cyclase activity and accumulates lycopene instead of beta-..
  91. pmc Induction of glutathione S-transferase in biofilms and germinating spores of Mucor hiemalis strain EH5 from cold sulfidic spring waters
    Enamul Hoque
    GSF National Research Center for Environment and Health, Institute of Groundwater Ecology, Ingolstadter Landstr 1, Neuherberg, Germany
    Appl Environ Microbiol 73:2697-707. 2007
    ..to the occurrence and activation of GST and the GST activities of the aquatic fungal strains EH5 and EH7 of Mucor hiemalis isolated for the first time from such waters...
  92. ncbi Relationship between spore germination kinetics and lag time during growth of Mucor racemosus
    P Dantigny
    Laboratoire de Microbiologie, UMR INRA 1082, ENS BANA, Dijon, France
    Lett Appl Microbiol 35:395-8. 2002
    ..This paper aims at establishing a relationship between the percentage of germinated spores and parameters easily available from visible development...
  93. ncbi Ethanol-induced dimorphism and lipid composition changes in Mucor fragilis CCMI 142
    I Serrano
    , Instituto Nacional de Engenharia e Tecnologia Industrial, , Lisboa, Portugal
    Lett Appl Microbiol 33:89-93. 2001
    AIMS: To study the effect of ethanol on morphology, lipid production and fatty acid profile of Mucor fragilis CCMI 142 cultures. METHODS AND RESULTS: Cell inhibition in shake flask cultures due to alcohol toxicity grew linearly from 0...
  94. ncbi [Sporangiospores of the fungus Mucor lusitanicus 12M: correlation between lipid composition, viability, and morphology of growth upon germination]
    N S Funtikova
    Institute of Microbiology, Russian Academy of Sciences, pr 60 letiya Oktyabrya 7, k 2, Moscow, 117312 Russia
    Mikrobiologiia 72:775-9. 2003
    We studied viability of sporangiospores from a surface culture of the fungus Mucor lusitanicus 12M grown on wheat bran...
  95. ncbi [Dimorphism of the fungus Mucor lusitanicus 12M depends on the cultivation conditions of sporangiospores]
    N S Funtikova
    Mikrobiologiia 73:851-3. 2004
  96. ncbi [Detection of extracellular protease in Mucor species]
    Maria Helena Alves
    Universidade de Sao Paulo USP, and NPCIAMB, Recife, and Coordenacão de Biologia, Universidade Estadual Vale do Acarau, Av da Universidade, 850 Betania, Sobral, CE, CEP 62040 370, Brazil
    Rev Iberoam Micol 22:114-7. 2005
    ..The species of genus Mucor are a group of fungal microbes with important biotechnological potential, which are responsible for production of ..
  97. ncbi Carneic acids A and B, chemotaxonomically significant antimicrobial agents from the xylariaceous ascomycete Hypoxylon carneum
    Dang Ngoc Quang
    Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro cho, Tokushima 770 8514, Japan
    J Nat Prod 69:1198-202. 2006
    ..carneum from different geographic regions, but do not constitute major metabolites of more than 100 species of Xylariaceae. Their biological and chemotaxonomic significance is discussed...
  98. ncbi Hydroxylation of 10-deoxoartemisinin by Cunninghamella elegans
    Igor A Parshikov
    Department of Medicinal Chemistry, University of Mississippi, University, Mississippi 38677 1848, USA
    J Nat Prod 67:1595-7. 2004
    ..The metabolites 2 and 4 retained an intact peroxide group and are therefore useful scaffolds for synthetic modification in the search for new antimalarial agents...
  99. ncbi Ester synthesis catalyzed by Mucor miehei lipase immobilized on magnetic polysiloxane-polyvinyl alcohol particles
    Laura M Bruno
    Embrapa Agroindustria Tropical, Rua Dra Sara Mesquita, 2270, Pici, 60511 110, Fortaleza CE, Brazil
    Appl Biochem Biotechnol 113:189-99. 2004
    b>Mucor miehei lipase was immobilized on magnetic polysiloxane-polyvinyl alcohol particles by covalent binding with high activity recovered...
  100. ncbi Chemoenzymatic synthesis and in vitro studies on the hydrolysis of antimicrobial monoglycosyl diglycerides by pancreatic lipase
    Francesca Cateni
    Department of Pharmaceutical Sciences, University of Trieste, P zle Europa 1, 34127 Trieste, Italy
    Bioorg Med Chem Lett 17:1971-8. 2007
    ..The stereoselectivity of pancreatic lipase was investigated in vitro where the preference for the 1 position in MGDGs is strictly related to the length of the acyl chains...
  101. ncbi A novel hydrophilic support, CoFoam, for enzyme immobilization
    P T Vasudevan
    Department of Chemical Engineering, University of New Hampshire, Durham, NH 03824, USA
    Biotechnol Lett 26:473-7. 2004
    Lipases from different sources (porcine pancreas, Mucor miehei and Candida antarctica B) were covalently immobilized on a hydrophilic polyurethane composite (CoFoam). Their hydrolytic activities assayed with tributyrin were 0.55, 2...

Research Grants54

  1. High Performance Mass Spectrometry for Diagnosis of Fungal Pathogens
    Thomas A Hall; Fiscal Year: 2010
    ..caused by various species of Aspergillus and Candida, but also several Fusarium species and Zygomycota such as Mucor, among others...
  2. Sexual reproduction and virulence of zygomycete fungi
    Joseph Heitman; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Mucor circinelloides and Rhizopus oryzae are the most prevalent causal agents of the deadly fungal infection, mucormycosis, which is an emerging disease in immunocompromised patients and the second ..
  3. RAS GENES AND REGULATION OF CELLULAR MORPHOGENESIS
    John Linz; Fiscal Year: 1991
    ..The filamentous fungus, Mucor racemosus, is induced to undergo three characteristic types of cellular morphogenesis in response to changes in ..
  4. REGULATORY ROLE OF CYCLIC NUCLEOTIDES IN MUCOR
    PETER BORGIA; Fiscal Year: 1980
    This proposal deals with studies concerning the regulation of beta-glucosidase expression in the dimorphic fungus Mucor racemosus...
  5. GENE STRUCTURE AND EF-1A IN THE FUNGUS MUCOR
    PAUL SYPHERD; Fiscal Year: 1990
    The protein synthesis factor EF-1Alpha of Mucor racemosus hyphae contains 8 or 9 methylated lysines per molecule, while the factor from assexual sporangiospores is non-methylated...
  6. Phenotypic Multi-Drug Adaptation in Mucor racemosus
    KEITH MCGEE; Fiscal Year: 2001
    ..thought and may be an important impediment to the control of microbes with antibiotics or disinfectants Thus Mucor may serve as an important model for phenotypic resistance systems in microorganisms...
  7. BIOCHEMISTRY OF MORPHOGENESIS IN MUCOR
    Salomon Bartnicki Garcia; Fiscal Year: 1980
    ..is an attempt to elucidate the biochemical mechanisms responsible for morphological differentiation in the fungus, Mucor rouxii. Our study is focused on the cell wall...
  8. PYRUVATE KINASE AND DEVELOPMENT IN MUCOR
    JOHN PAZNOKAS; Fiscal Year: 1980
    ..With Mucor, celluar differentiation is reversible; mycelia are converted to yeast by a vegetative process and, likewise, ..
  9. DEVELOPMENTAL CHANGES IN THE PROTEIN-SYNTHETIC APPARATUS
    PAUL SYPHERD; Fiscal Year: 1980
    This proposal deals with a study of modifications of the translational system which occur in the dimorphic fungus, Mucor racemosus...
  10. POST-TRANSCRIPTIONAL REGULATION OF GENE EXPRESSION
    PAUL SYPHERD; Fiscal Year: 1980
    This proposal deals with studies on the post-transcriptional regulation of protein synthesis in the fungus Mucor racemosus...
  11. MBRS-SCORE Program at Alcorn State University
    Bettaiya Rajanna; Fiscal Year: 2003
    ..by lead and methyl mercury in the develop rat brain; a pilot project on phenotypic multi-drug adaptation in Mucor recemosus...
  12. MBRS-SCORE Program at Alcorn State University
    Bettaiya Rajanna; Fiscal Year: 2001
    ..by lead and methyl mercury in the develop rat brain; a pilot project on phenotypic multi-drug adaptation in Mucor recemosus...
  13. MBRS-SCORE Program at Alcorn State University
    Bettaiya Rajanna; Fiscal Year: 2004
    ..by lead and methyl mercury in the develop rat brain; a pilot project on phenotypic multi-drug adaptation in Mucor recemosus...
  14. MBRS-SCORE Program at Alcorn State University
    Bettaiya Rajanna; Fiscal Year: 2002
    ..by lead and methyl mercury in the develop rat brain; a pilot project on phenotypic multi-drug adaptation in Mucor recemosus...
  15. Innate Effectors of rAls3p-N Anti-Candida Vaccine
    Brad J Spellberg; Fiscal Year: 2010
    ..PNS 398/2590 (Rev. 11/07) Page - Continuation Format Page ..
  16. Activated Targeted Killer (ATAK) Cells for Invasive Fungal Infections
    Brad J Spellberg; Fiscal Year: 2010
    ..Completion of the proposed studies will enable us to create a safe and effective strategy to overcome the barriers to white blood cell transfusions, revolutionizing the treatment of infections in cancer patients. ..
  17. Mechanisms of Als vaccine protection against S. aureus
    Brad J Spellberg; Fiscal Year: 2010
    ..The insights into fundamental immunological mechanisms of protection against S. aureus will also be of extreme importance to the development of other vaccine candidates targeting S. aureus in the future. ..
  18. Activated Targeted Killer (ATAK) Cells for Invasive Fungal Infections
    Brad Spellberg; Fiscal Year: 2009
    ..Completion of the proposed studies will enable us to create a safe and effective strategy to overcome the barriers to white blood cell transfusions, revolutionizing the treatment of infections in cancer patients. ..
  19. Innate Effectors of rAls3p-N Anti-Candida Vaccine
    Brad Spellberg; Fiscal Year: 2009
    ..PNS 398/2590 (Rev. 11/07) Page - Continuation Format Page ..
  20. Mechanisms of Als vaccine protection against S. aureus
    Brad Spellberg; Fiscal Year: 2009
    ..The insights into fundamental immunological mechanisms of protection against S. aureus will also be of extreme importance to the development of other vaccine candidates targeting S. aureus in the future. ..
  21. Mechanisms of Als vaccine protection against S. aureus
    Brad Spellberg; Fiscal Year: 2008
    ..The insights into fundamental immunological mechanisms of protection against S. aureus will also be of extreme importance to the development of other vaccine candidates targeting S. aureus in the future. ..
  22. Mechanisms of Als vaccine protection against S. aureus
    Brad Spellberg; Fiscal Year: 2007
    ..The insights into fundamental immunological mechanisms of protection against S. aureus will also be of extreme importance to the development of other vaccine candidates targeting S. aureus in the future. ..
  23. Adrenergic Antagonism During Murine Candidiasis
    Brad Spellberg; Fiscal Year: 2007
    ..For these reasons, the potential for adrenergic antagonism to act as an effective immunotherapy is highly meritorious of investigation in this training application. ..
  24. Adrenergic Antagonism During Murine Candidiasis
    Brad Spellberg; Fiscal Year: 2008
    ..For these reasons, the potential for adrenergic antagonism to act as an effective immunotherapy is highly meritorious of investigation in this training application. ..
  25. Treatment of Fungal Infections with ATAK Cells
    Ashraf Ibrahim; Fiscal Year: 2004
    ..Furthermore, the genetic construct targeting ATAK cells to Candida can easily be adapted to any other pathogen against which a MAb has been raised. ..
  26. Iron Uptake and Mucormycosis Pathogenesis
    Ashraf Ibrahim; Fiscal Year: 2006
    ..Completion of the proposed studies will enable investigation of treatments that block R. oryzae uptake of iron. [unreadable] [unreadable] [unreadable]..
  27. Iron Uptake and Mucormycosis Pathogenesis
    Ashraf Ibrahim; Fiscal Year: 2007
    ..Completion of the proposed studies will enable investigation of treatments that block R. oryzae uptake of iron. [unreadable] [unreadable] [unreadable]..
  28. Iron Uptake and Mucormycosis Pathogenesis
    Ashraf S Ibrahim; Fiscal Year: 2010
    ..Completion of the proposed studies will enable investigation of treatments that block R. oryzae uptake of iron. ..
  29. Risk Factors and Outcomes of Candidemia in Children
    Theoklis Zaoutis; Fiscal Year: 2007
    ....
  30. Novel Antifungal Strategies for Lethal Mucormycosis
    Ashraf Ibrahim; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  31. Mortality in Transplant Patients with Aspergillosis
    John Baddley; Fiscal Year: 2007
    ....
  32. Iron Uptake and Mucormycosis Pathogenesis
    Ashraf Ibrahim; Fiscal Year: 2009
    ..Completion of the proposed studies will enable investigation of treatments that block R. oryzae uptake of iron. ..
  33. Mortality in Transplant Patients with Aspergillosis
    John Baddley; Fiscal Year: 2008
    ....
  34. Iron Uptake and Mucormycosis Pathogenesis
    Ashraf Ibrahim; Fiscal Year: 2008
    ..Completion of the proposed studies will enable investigation of treatments that block R. oryzae uptake of iron. ..
  35. Risk Factors and Outcomes of Candidemia in Children
    Theoklis Zaoutis; Fiscal Year: 2008
    ....