penicillium

Summary

Summary: A mitosporic Trichocomaceae fungal genus that develops fruiting organs resembling a broom. When identified, teleomorphs include Eupenicillium and TALAROMYCES. Several species (but especially PENICILLIUM CHRYSOGENUM) are sources of the antibiotic penicillin.

Top Publications

  1. ncbi Glucose oxidase from Penicillium amagasakiense. Primary structure and comparison with other glucose-methanol-choline (GMC) oxidoreductases
    M Kiess
    Department of Molecular Structure Research, Gesellschaft fur Biotechnologische Forschung, Braunschweig, Germany
    Eur J Biochem 252:90-9. 1998
  2. doi Sex in Penicillium: combined phylogenetic and experimental approaches
    M López-Villavicencio
    Origine, Structure, Evolution de la Diversité, UMR 7205 CNRS MNHN, Museum national d histoire naturelle, CP39, 57 rue Cuvier, 75231 Paris Cedex 05, France
    Fungal Genet Biol 47:693-706. 2010
  3. doi Characterization of beta-glucosidase from a strain of Penicillium purpurogenum KJS506
    Marimuthu Jeya
    Department of Chemical Engineering, Konkuk University, Seoul, 143 701, South Korea
    Appl Microbiol Biotechnol 86:1473-84. 2010
  4. ncbi Penicinoline, a new pyrrolyl 4-quinolinone alkaloid with an unprecedented ring system from an endophytic fungus Penicillium sp
    Chang Lun Shao
    Key Laboratory of Marine Drugs, The Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People s Republic of China
    Bioorg Med Chem Lett 20:3284-6. 2010
  5. pmc Germination of penicillium paneum Conidia is regulated by 1-octen-3-ol, a volatile self-inhibitor
    Gilma S Chitarra
    Laboratory of Food Microbiology, Wageningen University, 6703 HD Wageningen, The Netherlands
    Appl Environ Microbiol 70:2823-9. 2004
  6. doi A fungal sexual revolution: Aspergillus and Penicillium show the way
    Paul S Dyer
    School of Biology, University Park, University of Nottingham, Nottingham, NG7 2RD, UK
    Curr Opin Microbiol 14:649-54. 2011
  7. ncbi Penicillium parvulum and Penicillium georgiense, sp. nov., isolated from the conidial heads of Aspergillus species
    Stephen W Peterson
    Microbial Genomics and Bioprocessing Research Unit, National Center for Agricultural Utilization Research, Agricultural Research Service, U S Department of Agriculture, Peoria, Illinois 61604, USA
    Mycologia 101:71-83. 2009
  8. pmc Differences in clinical and laboratory diagnostic characteristics of penicilliosis marneffei in human immunodeficiency virus (HIV)- and non-HIV-infected patients
    S S Wong
    Division of Infectious Diseases, Department of Microbiology, The University of Hong Kong
    J Clin Microbiol 39:4535-40. 2001
  9. pmc Chemical epigenetics alters the secondary metabolite composition of guttate excreted by an atlantic-forest-soil-derived Penicillium citreonigrum
    Xiaoru Wang
    Natural Products Discovery Group, Department of Chemistry and Biochemistry, 620 Parrington Oval, Room 208, and Ecology and Evolutionary Biology Program, University of Oklahoma, Norman, Oklahoma 73019 3032, USA
    J Nat Prod 73:942-8. 2010
  10. pmc The G-protein alpha-subunit GasC plays a major role in germination in the dimorphic fungus Penicillium marneffei
    Sophie Zuber
    Department of Genetics, University of Melbourne, 3010 Victoria, Australia
    Genetics 164:487-99. 2003

Detail Information

Publications303 found, 100 shown here

  1. ncbi Glucose oxidase from Penicillium amagasakiense. Primary structure and comparison with other glucose-methanol-choline (GMC) oxidoreductases
    M Kiess
    Department of Molecular Structure Research, Gesellschaft fur Biotechnologische Forschung, Braunschweig, Germany
    Eur J Biochem 252:90-9. 1998
    The complete amino acid sequence of glucose oxidase from Penicillium amagasakiense was determined by Edman degradation and mass spectrometry of peptide fragments derived from three different specific proteolytic digests and a cyanogen ..
  2. doi Sex in Penicillium: combined phylogenetic and experimental approaches
    M López-Villavicencio
    Origine, Structure, Evolution de la Diversité, UMR 7205 CNRS MNHN, Museum national d histoire naturelle, CP39, 57 rue Cuvier, 75231 Paris Cedex 05, France
    Fungal Genet Biol 47:693-706. 2010
    We studied the mode of reproduction and its evolution in the fungal subgenus Penicillium Biverticillium using phylogenetic and experimental approaches...
  3. doi Characterization of beta-glucosidase from a strain of Penicillium purpurogenum KJS506
    Marimuthu Jeya
    Department of Chemical Engineering, Konkuk University, Seoul, 143 701, South Korea
    Appl Microbiol Biotechnol 86:1473-84. 2010
    A novel beta-glucosidase (BGL)-producing strain was isolated and identified as Penicillium purpurogenum KJS506 based on its morphology and internal transcribed spacer (ITS) rDNA gene sequence...
  4. ncbi Penicinoline, a new pyrrolyl 4-quinolinone alkaloid with an unprecedented ring system from an endophytic fungus Penicillium sp
    Chang Lun Shao
    Key Laboratory of Marine Drugs, The Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People s Republic of China
    Bioorg Med Chem Lett 20:3284-6. 2010
    ..The structure of 1a was unambiguously confirmed by single-crystal X-ray analysis. Penicinoline (1) showed potent in vitro cytotoxicity toward 95-D and HepG2 cell lines with IC(50) values of 0.57 and 6.5 microg/mL, respectively...
  5. pmc Germination of penicillium paneum Conidia is regulated by 1-octen-3-ol, a volatile self-inhibitor
    Gilma S Chitarra
    Laboratory of Food Microbiology, Wageningen University, 6703 HD Wageningen, The Netherlands
    Appl Environ Microbiol 70:2823-9. 2004
    b>Penicillium paneum is an important contaminant of cereal grains which is able to grow at low temperature, low pH, high levels of carbon dioxide, and under acid conditions. P...
  6. doi A fungal sexual revolution: Aspergillus and Penicillium show the way
    Paul S Dyer
    School of Biology, University Park, University of Nottingham, Nottingham, NG7 2RD, UK
    Curr Opin Microbiol 14:649-54. 2011
    ..Using experimental and genomic findings from Aspergillus and Penicillium species as examples, it is argued that evidence such as the presence and expression of apparently functional ..
  7. ncbi Penicillium parvulum and Penicillium georgiense, sp. nov., isolated from the conidial heads of Aspergillus species
    Stephen W Peterson
    Microbial Genomics and Bioprocessing Research Unit, National Center for Agricultural Utilization Research, Agricultural Research Service, U S Department of Agriculture, Peoria, Illinois 61604, USA
    Mycologia 101:71-83. 2009
    Two new Penicillium species were isolated from peanut-field soils in Georgia. The species were noted particularly because they sporulated on the conidial heads of Aspergillus species...
  8. pmc Differences in clinical and laboratory diagnostic characteristics of penicilliosis marneffei in human immunodeficiency virus (HIV)- and non-HIV-infected patients
    S S Wong
    Division of Infectious Diseases, Department of Microbiology, The University of Hong Kong
    J Clin Microbiol 39:4535-40. 2001
    ..By a Penicillium marneffei-specific mannoprotein Mp1p enzyme-linked immunosorbent assay, serum antigen titers were found to be ..
  9. pmc Chemical epigenetics alters the secondary metabolite composition of guttate excreted by an atlantic-forest-soil-derived Penicillium citreonigrum
    Xiaoru Wang
    Natural Products Discovery Group, Department of Chemistry and Biochemistry, 620 Parrington Oval, Room 208, and Ecology and Evolutionary Biology Program, University of Oklahoma, Norman, Oklahoma 73019 3032, USA
    J Nat Prod 73:942-8. 2010
    Chemical epigenetic manipulation of Penicillium citreonigrum led to profound changes in the secondary metabolite profile of its guttate...
  10. pmc The G-protein alpha-subunit GasC plays a major role in germination in the dimorphic fungus Penicillium marneffei
    Sophie Zuber
    Department of Genetics, University of Melbourne, 3010 Victoria, Australia
    Genetics 164:487-99. 2003
    The opportunistic human pathogen Penicillium marneffei exhibits a temperature-dependent dimorphic switch. At 25 degrees, multinucleate, septate hyphae that can undergo differentiation to produce asexual spores (conidia) are produced...
  11. ncbi Aspergillus and Penicillium allergens: focus on proteases
    Horng Der Shen
    Department of Medical Research and Education, Taipei Veterans General Hospital, Shih Pai, Taipei, 11217, Taiwan
    Curr Allergy Asthma Rep 7:351-6. 2007
    b>Penicillium and Aspergillus species are prevalent airborne fungi. It is imperative to identify and characterize their major allergens...
  12. pmc A transcriptomic approach highlights induction of secondary metabolism in citrus fruit in response to Penicillium digitatum infection
    Luis González-Candelas
    Departamento de Ciencia de los Alimentos, Instituto de Agroquimica y Tecnologia de Alimentos CSIC, Apartado de Correos 73, Burjassot, E46100 Valencia, Spain
    BMC Plant Biol 10:194. 2010
    Postharvest losses of citrus fruit due to green mold decay, caused by the fungus Penicillium digitaum, have a considerable economic impact...
  13. ncbi The plant growth-promoting fungus Penicillium simplicissimum GP17-2 induces resistance in Arabidopsis thaliana by activation of multiple defense signals
    Md Motaher Hossain
    United Graduate School of Agricultural Sciences, Gifu University, Yanagido 1 1, Gifu, Japan
    Plant Cell Physiol 48:1724-36. 2007
    Arabidopsis thaliana grown in soil amended with barley grain inocula of Penicillium simplicissimum GP17-2 or receiving root treatment with its culture filtrate (CF) exhibited clear resistance to Pseudomonas syringae pv...
  14. pmc Fungal indole alkaloid biosynthesis: genetic and biochemical investigation of the tryptoquialanine pathway in Penicillium aethiopicum
    Xue Gao
    Department of Chemical and Biomolecular Engineering, University of California Los Angeles, Los Angeles, California 90095, USA
    J Am Chem Soc 133:2729-41. 2011
    ..This work provides new genetic and biochemical insights into the biosynthesis of this group of fungal alkaloids, including the tremorgens related to 2...
  15. ncbi Discrimination of Penicillium isolates by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry fingerprinting
    Justin M Hettick
    Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Health Effects Laboratory Division, 1095 Willowdale Road, Morgantown, WV 26505, USA
    Rapid Commun Mass Spectrom 22:2555-60. 2008
    ..spectrometry (MALDI-TOF MS) was used to generate highly reproducible mass spectral 'fingerprints' for twelve Penicillium species...
  16. ncbi Disseminated Penicillium marneffei infection among HIV-infected patients in Manipur state, India
    K H Ranjana
    Department of Microbiology, J N Medical Hospital, Imphal 795001, Manipur, India
    J Infect 45:268-71. 2002
    To further describe the clinical and epidemiological characteristics of Penicillium marneffei infection in human immunodeficiency virus (HIV) infected patients in India.
  17. doi Penicillium araracuarense sp. nov., Penicillium elleniae sp. nov., Penicillium penarojense sp. nov., Penicillium vanderhammenii sp. nov. and Penicillium wotroi sp. nov., isolated from leaf litter
    Jos Houbraken
    CBS KNAW Fungal Biodiversity Centre, PO Box 85167, 3508 AD Utrecht, The Netherlands
    Int J Syst Evol Microbiol 61:1462-75. 2011
    Several species of the genus Penicillium were isolated during a survey of the mycobiota of leaf litter and soil in Colombian Amazon forest. Five species, Penicillium penarojense sp. nov...
  18. ncbi Identity and effects of quorum-sensing inhibitors produced by Penicillium species
    Thomas Bovbjerg Rasmussen
    Center for Biomedical Microbiology, BioCentrum DTU, Technical University of Denmark, DK 2800 Kgs Lyngby, Denmark
    Microbiology 151:1325-40. 2005
    ..During a screening of 100 extracts from 50 Penicillium species, 33 were found to produce QS inhibitory (QSI) compounds...
  19. pmc Penicillium marneffei infection and recent advances in the epidemiology and molecular biology aspects
    Nongnuch Vanittanakom
    Department of Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand
    Clin Microbiol Rev 19:95-110. 2006
    b>Penicillium marneffei infection is an important emerging public health problem, especially among patients infected with human immunodeficiency virus in the areas of endemicity in southeast Asia, India, and China. Within these regions, P...
  20. pmc Identification of novel hexapeptides bioactive against phytopathogenic fungi through screening of a synthetic peptide combinatorial library
    Belen Lopez-Garcia
    Departamento de Ciencia de los Alimentos, Instituto de Agroquimica y Tecnologia de Alimentos CSIC, E 46100 Valencia, Spain
    Appl Environ Microbiol 68:2453-60. 2002
    ..PAF32 (Ac-rkwhfw-NH(2)), and PAF34 (Ac-rkwlfw-NH(2)) showed stronger activity than PAF19 against isolates of Penicillium digitatum, Penicillium italicum, and Botrytis cinerea...
  21. doi Microsatellite loci to recognize species for the cheese starter and contaminating strains associated with cheese manufacturing
    Frederic Giraud
    Museum national d histoire naturelle, Departement Systematique et Evolution, UMR OSEB 7205, CP 39, 57 rue Cuvier, 75231 Paris Cedex 05, France
    Int J Food Microbiol 137:204-13. 2010
    We report the development of 17 microsatellite markers in the cheese fungi Penicillium camemberti and P. roqueforti, using an enrichment protocol. Polymorphism and cross-amplification were explored using 23 isolates of P...
  22. ncbi Development of a highly efficient gene targeting system allowing rapid genetic manipulations in Penicillium decumbens
    Zhong Hai Li
    State Key Laboratory of Microbial Technology, Shandong University, 27 Shanda South Road, Jinan, 250100, People s Republic of China
    Appl Microbiol Biotechnol 87:1065-76. 2010
    b>Penicillium decumbens is an important industrial filamentous fungus and has been widely used in biorefinery due to its high production of cellulase and hemicellulase...
  23. ncbi Production of galacto-manno-oligosaccharides from guar gum by beta-mannanase from Penicillium oxalicum SO
    Masahiro Kurakake
    Department of Applied Biological Science, Fukuyama University, Sanzou, Gakuenchou 1 banchi, Fukuyama, Hiroshima 729 0292, Japan
    J Agric Food Chem 54:7885-9. 2006
    Beta-mannanase from Penicillium oxalicum SO efficiently hydrolyzed guar galactomannan to galacto-manno-oligosaccharides. Gel filtration estimated the molecular weight of the beta-mannanase as 35 000 and SDS-PAGE as 29 000...
  24. pmc G-protein signaling mediates asexual development at 25 degrees C but has no effect on yeast-like growth at 37 degrees C in the dimorphic fungus Penicillium mameffei
    Sophie Zuber
    Department of Genetics, University of Melbourne, 3010 Victoria, Australia
    Eukaryot Cell 1:440-7. 2002
    The ascomycete Penicillium marneffei is an opportunistic human pathogen exhibiting a temperature-dependent dimorphic switch. At 25 degrees C, P...
  25. ncbi Atypical cutaneous lesions of Penicillium marneffei infection as a manifestation of the immune reconstitution inflammatory syndrome after highly active antiretroviral therapy
    Lahari Saikia
    Department of Microbiology, Assam Medical College, Dibrugarh 786 002, India
    Indian J Dermatol Venereol Leprol 76:45-8. 2010
    b>Penicillium marneffei infections normally manifest as molluscum contagiosum like skin lesion in HIV-infected persons. We report a case with verrucous lesions over nose and face due to Penicillium marneffei infection after HAART treatment...
  26. pmc Sporicidal activity of synthetic antifungal undecapeptides and control of Penicillium rot of apples
    Esther Badosa
    Laboratory of Plant Pathology, Institute of Food and Agricultural Technology CIDSAV XaRTA, University of Girona, Campus Montilivi, 17071 Girona, Spain
    Appl Environ Microbiol 75:5563-9. 2009
    ..A set of 15 sequences was screened in vitro against Fusarium oxysporum, Penicillium expansum, Aspergillus niger, and Rhizopus stolonifer. Most compounds were highly active against F...
  27. ncbi High concentration ethanol production from corncob residues by fed-batch strategy
    Kai Liu
    State Key Laboratory of Microbial Technology, National Glycoengineering Research Center, Shangdong University, No 27 Shanda Nan Road, Jinan Shandong 250100, China
    Bioresour Technol 101:4952-8. 2010
    ..Simultaneous saccharification and fermentation (SSF) was performed by adding crude cellulase preparations from Penicillium decumbens JUA10-1 at 30 degrees C...
  28. ncbi A novel cellulase free alkaliphilic xylanase from alkali tolerant Penicillium citrinum: production, purification and characterization
    T Dutta
    Department of Biochemistry, University College of Science, Calcutta University, Kolkata, West Bengal, India
    Lett Appl Microbiol 44:206-11. 2007
    ..The enzymatic hydrolysis of xylan has potential economic and environment-friendly applications. Therefore, attention is focused here on the discovery of new extremophilic xylanase in order to meet the requirements of industry...
  29. ncbi Anti-tumor effects of Rubratoxin B on cell toxicity, inhibition of cell proliferation, cytotoxic activity and matrix metalloproteinase-2,9
    Tao Wang
    Department of Pharmacognosy, Kyoto Pharmaceutical University, Kyoto 607 8412, Japan
    Toxicol In Vitro 21:646-50. 2007
    ..A bioassay-guided fractionation of soil fungus Penicillium purpurogenum fermentation, yielded the metabolite Rubratoxin B using morphological deformation of Pyricularia ..
  30. ncbi Filipin is a reliable in situ marker of ergosterol in the plasma membrane of germinating conidia (spores) of Penicillium discolor and stains intensively at the site of germ tube formation
    M R Van Leeuwen
    Applied and Industrial Mycology, CBS Fungal Biodiversity Centre, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands
    J Microbiol Methods 74:64-73. 2008
    ..Germinating conidia of Penicillium discolor stained with filipin, displayed a fluorescent cap at the location of germ tube appearance and ..
  31. ncbi Characterization of genetic and biochemical mechanisms of fludioxonil and pyrimethanil resistance in field isolates of Penicillium digitatum
    L Kanetis
    Department of Plant Pathology, University of California, Riverside, CA 92521, USA
    Phytopathology 98:205-14. 2008
    Genetic and biochemical mechanisms of fludioxonil and pyrimethanil resistance in isolates of Penicillium digitatum were evaluated and compared to those characterized in other fungi...
  32. doi Physiological traits of Penicillium glabrum strain LCP 08.5568, a filamentous fungus isolated from bottled aromatized mineral water
    L Nevarez
    Universite Europeenne de Bretagne, France
    Int J Food Microbiol 130:166-71. 2009
    b>Penicillium glabrum is a ubiquitous fungus distributed world wide. This fungus is a frequent contaminant in the food manufacturing industry...
  33. doi Studies on silver nanoparticles synthesized by a marine fungus, Penicillium fellutanum isolated from coastal mangrove sediment
    K Kathiresan
    Centre of Advanced Study in Marine Biology, Annamalai University, Parangipettai 608502, Tamil Nadu, India
    Colloids Surf B Biointerfaces 71:133-7. 2009
    In this work, in vitro biosynthesis of silver nanoparticles was achieved using AgNO(3) as a substrate by Penicillium fellutanum isolated from coastal mangrove sediment...
  34. doi Genome shuffling improves production of cellulase by Penicillium decumbens JU-A10
    Y Cheng
    State Key Laboratory of Microbial Technology, National Glycoengineering Reserch Center, Shandong University, Jinan, China
    J Appl Microbiol 107:1837-46. 2009
    Improvement of cellulase production of Penicillium decumbens by genome shuffling of an industrial catabolite-repression-resistant strain JU-A10 with its mutants.
  35. ncbi Mold-inhibitory activity of different yeast species during airtight storage of wheat grain
    Ulrika Adel Druvefors
    Department of Microbiology, Swedish University of Agricultural Sciences SLU, P O Box 7025, SE 750 07 Uppsala, Sweden
    FEMS Yeast Res 5:373-8. 2005
    The yeast Pichia anomala J121 inhibits spoilage by Penicillium roqueforti in laboratory and pilot studies with high-moisture wheat in malfunctioning airtight storage...
  36. pmc Genome sequence of the necrotrophic fungus Penicillium digitatum, the main postharvest pathogen of citrus
    Marina Marcet-Houben
    Centre for Genomic Regulation, Barcelona, Spain
    BMC Genomics 13:646. 2012
    b>Penicillium digitatum is a fungal necrotroph causing a common citrus postharvest disease known as green mold...
  37. pmc Household airborne Penicillium associated with peak expiratory flow variability in asthmatic children
    Kemp W Bundy
    Department of Medicine, Division of Allergy Immunology and Rheumatology, University of Rochester Medical Center, Rochester, New York 14642, USA
    Ann Allergy Asthma Immunol 103:26-30. 2009
    ..Exposure to airborne fungi has been associated with increased airway hyperreactivity and asthma prevalence...
  38. ncbi Natural formation of styrene by cinnamon mold flora
    J L Lafeuille
    McCormick France, McCormick Europe Central Analysis Laboratory, 84210 Carpentras, France
    J Food Sci 74:M276-83. 2009
    ..An investigation into the ability of the 5 species of mold to produce styrene showed that 3 of them--namely, Penicillium citrinum, Penicillium oxalicum, Aspergillus niger--produced styrene in vitro in buffered peptone water at 25 ..
  39. doi Characterization and kinetic analysis of a thermostable GH3 beta-glucosidase from Penicillium brasilianum
    Kristian B R M Krogh
    Center for Microbial Biotechnology, Technical University of Denmark, Building 223, 2800 Lyngby, Denmark
    Appl Microbiol Biotechnol 86:143-54. 2010
    A GH3 beta-glucosidase (BGL) from Penicillium brasilianum was purified to homogeneity after cultivation on a cellulose and xylan rich medium...
  40. doi Cloning, characterization and heterologous expression of the first Penicillium echinulatum cellulase gene
    M R Rubini
    Department of Cellular Biology, Institute of Biological Sciences, University of Brasilia, Brasilia DF, Brazil
    J Appl Microbiol 108:1187-98. 2010
    b>Penicillium echinulatum is effective for bioconversion processes. However, nothing is known about the molecular biology of its cellulolytic system. We describe for the first time the isolation, cloning and expression of a P...
  41. doi High-level production of a thermoacidophilic beta-glucosidase from Penicillium citrinum YS40-5 by solid-state fermentation with rice bran
    I Son Ng
    Biotechnology Center in Southern Taiwan, Academia Sinica, 2F, No 22, Lane 31, Sec 1, Huandong Rd, Sinshih Township, Tainan 74146, Taiwan, ROC
    Bioresour Technol 101:1310-7. 2010
    ..pNPG) was achieved by rice bran-based solid-state fermentation (SSF) of the recently characterized fungus Penicillium citrinum YS40-5...
  42. ncbi Antimicrobial properties of derivatives of the cationic tryptophan-rich hexapeptide PAF26
    Alberto Munoz
    Instituto de Agroquimica y Tecnologia de Alimentos IATA CSIC, Apartado de Correos 73, Burjassot, 46100 Valencia, Spain
    Biochem Biophys Res Commun 354:172-7. 2007
    ..PAF26 is a hexapeptide identified previously by a combinatorial approach against the fungus Penicillium digitatum and shows antimicrobial properties towards certain phytopathogenic fungi...
  43. doi The mycobiota of three dry-cured meat products from Slovenia
    Silva Sonjak
    Department of Biology, Biotechnical Faculty, University of Ljubljana, Vecna pot 111, SI 1000 Ljubljana, Slovenia
    Food Microbiol 28:373-6. 2011
    ..The predominant filamentous fungal genus isolated was Penicillium. Eurotium spp., Aspergillus versicolor and Cladosporium spp. were isolated from only two of the products...
  44. ncbi Purification and characterization of vanillyl-alcohol oxidase from Penicillium simplicissimum. A novel aromatic alcohol oxidase containing covalently bound FAD
    E de Jong
    Department of Food Science, Agriculture University, Wageningen, The Netherlands
    Eur J Biochem 208:651-7. 1992
    Vanillyl-alcohol oxidase was purified 32-fold from Penicillium simplicissimum, grown on veratryl alcohol as its sole source of carbon and energy. SDS/PAGE of the purified enzyme reveals a single fluorescent band of 65 kDa...
  45. doi Transcriptomic profiling of citrus fruit peel tissues reveals fundamental effects of phenylpropanoids and ethylene on induced resistance
    Ana Rosa Ballester
    Instituto de Agroquimica y Tecnologia de Alimentos, Consejo Superior de Investigaciones Científicas IATA CSIC, Valencia, Spain
    Mol Plant Pathol 12:879-97. 2011
    b>Penicillium spp. are the major postharvest pathogens of citrus fruit in Mediterranean climatic regions...
  46. ncbi The chitinolytic activity of Penicillium janthinellum P9: purification, partial characterization and potential applications
    R Di Giambattista
    Dipartimento di Agrobiologia e Agrochimica, University of Tuscia, Viterbo-01100, Italy
    J Appl Microbiol 91:498-505. 2001
    AIMS: To purify and characterize the chitinolytic activity of Penicillium janthinellum P9 and to evaluate possible uses of the purified enzymes in the control of fungal growth and spore germination...
  47. ncbi Ochratoxin A in airborne dust and fungal conidia
    M A Skaug
    Department of Agriculture and Natural Science, Hedmark College, Ridabu, Norway
    Mycopathologia 151:93-8. 2001
    ..08 to 0.21 mg/m3. Conidia collected from cultures of Penicillium verrucosum and Aspergillus ochraceus contained 0.4-0.7 and 0.02-0.06 pg OTA per conidium, respectively...
  48. doi Improvement of cellulase activity in Trichoderma reesei by heterologous expression of a beta-glucosidase gene from Penicillium decumbens
    Liang Ma
    Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China
    Enzyme Microb Technol 49:366-71. 2011
    ..In this study, a beta-glucosidase I coding sequence from Penicillium decumbens was ligated with the cellobiohydrolase I (cbh1) promoter of T...
  49. pmc Clonality despite sex: the evolution of host-associated sexual neighborhoods in the pathogenic fungus Penicillium marneffei
    Daniel A Henk
    Department of Infectious Disease Epidemiology, Imperial College, Norfolk Place, London, United Kingdom
    PLoS Pathog 8:e1002851. 2012
    ..However, genetic data have shown the AIDS-associated pathogen Penicillium marneffei to have extensive spatial genetic structure at local and regional scales, and although there has been ..
  50. pmc Activation of the dormant secondary metabolite production by introducing gentamicin-resistance in a marine-derived Penicillium purpurogenum G59
    Yun Jing Chai
    Beijing Institute of Pharmacology and Toxicology, 27 Tai Ping Road, Haidian District, Beijing 100850, China
    Mar Drugs 10:559-82. 2012
    ..has been developed by introducing gentamicin-resistance to an originally inactive, marine-derived fungal strain Penicillium purpurogenum G59...
  51. doi Triazole and dihydroimidazole alkaloids from the marine sediment-derived fungus Penicillium paneum SD-44
    Chun Shun Li
    Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Nanhai Road 7, Qingdao 266071, People s Republic of China
    J Nat Prod 74:1331-4. 2011
    ..and a very recently reported quinazolinone derivative (4) were isolated from the marine sediment-derived fungus Penicillium paneum SD-44...
  52. doi Ameliorative symbiosis of endophyte (Penicillium funiculosum LHL06) under salt stress elevated plant growth of Glycine max L
    Abdul Latif Khan
    School of Applied Biosciences, Kyungpook National University, Sangyuk Dong, Buk Gu, Daegu 702 701, South Korea
    Plant Physiol Biochem 49:852-61. 2011
    ..L cv. Hwangkeum-kong) growing under salinity stress. GMC-2A was identified as a new strain of Penicillium funiculosum on the basis of sequence homology and phylogenetic analysis of D1/D2 regions of 28S rDNA...
  53. doi A taxonomic and ecological overview of cheese fungi
    Jeanne Ropars
    Museum national d histoire naturelle, Departement Systematique et Evolution, UMR MNHN CNRS 7205, CP 39, 57 rue Cuvier, 75231 Paris Cedex 05, France
    Int J Food Microbiol 155:199-210. 2012
    ..Apart from the emblematic species, Penicillium camemberti and Penicillium roqueforti, cheese fungi are not well known...
  54. doi Complete mitochondrial genome sequence of the phytopathogenic fungus Penicillium digitatum and comparative analysis of closely related species
    Xuepeng Sun
    Institute of Biotechnology, Zhejiang University, Hangzhou, Zhejiang, China
    FEMS Microbiol Lett 323:29-34. 2011
    The complete mitochondrial genome of Penicillium digitatum (Pers.:Fr) Sacc is reported, the first time in a phytopathogenic Penicillium species...
  55. pmc GH10 xylanase D from Penicillium funiculosum: biochemical studies and xylooligosaccharide production
    Mickael Lafond
    Universite Paul Cezanne, Faculté des Sciences et Techniques Saint Jérôme, 13397 Marseille Cedex 20, France
    Microb Cell Fact 10:20. 2011
    The filamentous fungus Penicillium funiculosum produces a range of glycoside hydrolases (GH). The XynD gene, encoding the sole P...
  56. doi Effect of heat shock treatment on stress tolerance and biocontrol efficacy of Metschnikowia fructicola
    Jia Liu
    US Department of Agriculture Agricultural Research Service USDA ARS, Kearneysville, WV 25430, USA
    FEMS Microbiol Ecol 76:145-55. 2011
    ..Additionally, HS-treated yeast exhibited significantly greater (P<0.0001) biocontrol activity against Penicillium expansum and a significantly faster (P<0...
  57. ncbi Characterization of the endoglucanase and glucomannanase activities of a glycoside hydrolase family 45 protein from Penicillium decumbens 114-2
    Guodong Liu
    State Key Laboratory of Microbial Technology, Shandong University, Jinan, Shandong, P R China
    J Gen Appl Microbiol 56:223-9. 2010
    ..To our knowledge, this is the first report of characterization of a GH family 45 protein from Penicillium species...
  58. ncbi Azaphilone and isocoumarin derivatives from the endophytic fungus Penicillium sclerotiorum PSU-A13
    Jiraporn Arunpanichlert
    Department of Chemistry and Center for Innovation in Chemistry, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla, Thailand
    Chem Pharm Bull (Tokyo) 58:1033-6. 2010
    ..new isocoumarin, penicilisorin (3), together with six known compounds were isolated from the endophytic fungus Penicillium sclerotiorum PSU-A13. Their structures were identified by analysis of spectroscopic data...
  59. ncbi Discontinuation of secondary prophylaxis against penicilliosis marneffei in AIDS patients after HAART
    Romanee Chaiwarith
    Department of Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand
    AIDS 21:365-7. 2007
    ..The observed incidence of relapse of penicilliosis marneffei was zero cases per 641 person-months (95% confidence interval 0-0.6 cases per person-month) after a median follow-up of 18 months (range 6-45)...
  60. ncbi Use of chemosensitization to overcome fludioxonil resistance in Penicillium expansum
    J H Kim
    Plant Mycotoxin Research Unit, Western Regional Research Center, USDA ARS, Albany, CA, USA
    Lett Appl Microbiol 51:177-83. 2010
    To overcome fludioxonil resistance of Penicillium expansum, a mycotoxigenic fungal pathogen causing postharvest decay in apple, by using natural phenolic chemosensitizing agents.
  61. doi Multilocus sequence identification of Penicillium species in cork bark during plank preparation for the manufacture of stoppers
    Rita Serra
    IBB Institute for Biotechnology and Bioengineering, Centre of Biological Engineering, University of Minho, Campus de Gualtar, 4710 057 Braga, Portugal
    Res Microbiol 159:178-86. 2008
    Despite several studies reporting Penicillium as one of the most frequent fungal genera in cork planks, the isolates were rarely identified to species level...
  62. ncbi Penicillium astrolabium and Penicillium neocrassum, two new species isolated from grapes and their phylogenetic placement in the P. olsonii and P. brevicompactum clade
    Rita Serra
    Centro de Engenharia Biólogica, Universidade do Minho, Campus de Gualtar, 4710 057 Braga, Portugal
    Mycologia 99:78-87. 2007
    We describe two new terverticillate Penicillium species isolated from grapes on the basis of phenotypic and phylogenetic differences from known species...
  63. ncbi Citrate efflux in glucose-limited and glucose-sufficient chemostat culture of Penicillium simplicissium
    M Gallmetzer
    Institute of Microbiology, University of Innsbruck, Austria
    Antonie Van Leeuwenhoek 79:81-7. 2001
    Citrate excretion by Penicillium simplicissimum was investigated in a chemostat. Carbon-limited grown P. simplicissimum did not excrete no citrate. Citrate was excreted, however, when growth was nitrogen-limited...
  64. pmc Development and evaluation of rapid urinary antigen detection tests for diagnosis of penicilliosis marneffei
    Varunee Desakorn
    Clinical Infectious Diseases Research Unit, Department of Clinical Tropical Medicine, Faculty of Tropical Medicine Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    J Clin Microbiol 40:3179-83. 2002
    Penicilliosis, caused by the dimorphic fungus Penicillium marneffei, is an important opportunistic systemic fungal infection affecting immunocompromised individuals living in areas where penicilliosis is endemic...
  65. pmc Genital ulcer caused by Penicillium marneffei in an HIV-infected patient
    Vamseedhar Annam
    Sex Transm Infect 83:249-50. 2007
  66. pmc MP1 encodes an abundant and highly antigenic cell wall mannoprotein in the pathogenic fungus Penicillium marneffei
    L Cao
    Department of Microbiology, The University of Hong Kong
    Infect Immun 66:966-73. 1998
    ..the MP1 gene, which encodes an abundant antigenic cell wall mannoprotein from the dimorphic pathogenic fungus Penicillium marneffei. MP1 is a unique gene without homologs in sequence databases...
  67. ncbi A new species of Penicillium, P. ramulosum sp. nov., from the natural environment
    Cobus M Visagie
    Department of Microbiology, University of Stellenbosch, Private Bag X1, Matieland, 7602, South Africa
    Mycologia 101:888-95. 2009
    During a recent survey of Penicillium spp. from fynbos soils in the Western Cape Province of South Africa, several undescribed species were isolated...
  68. ncbi A simple method for extraction of fungal genomic DNA
    T H Al-Samarrai
    Institute of Molecular Biosciences, Massey University, Palmerston North, New Zealand
    Lett Appl Microbiol 30:53-6. 2000
    ..flavus, Fusarium graminarum, Neotyphodium lolii, Penicillium citrinum and Rhizopus nigricanes. The DNA was digestible with EcoRI, HindIII, SalI and BamHI...
  69. ncbi Effect of chitin on the antagonistic activity of Cryptococcus laurentii against Penicillium expansum in pear fruit
    Ting Yu
    Department of Food Science and Nutrition, Zhejiang University, Hangzhou, 310029, People s Republic of China
    Int J Food Microbiol 122:44-8. 2008
    ..chitin on the antagonistic activity of Cryptococcus laurentii against the postharvest blue mold rot caused by Penicillium expansum in pear fruit. The results showed that the antagonistic activity of C...
  70. ncbi [A comparative analysis of the clinical and laboratory characteristics in disseminated penicilliosis marneffei in patients with and without human immunodeficiency virus infection]
    Jian Quan Zhang
    Department of Respiratory Diseases, The First Affiliated Hospital of Guangxi Medical University, Nanning 530022, China
    Zhonghua Jie He He Hu Xi Za Zhi 31:740-6. 2008
    ..To study the differences in the clinical and laboratory characteristics of disseminated penicilliosis marneffei (PSM) in patients with and without human immunodeficiency virus (HIV) infection...
  71. pmc The protease allergen Pen c 13 induces allergic airway inflammation and changes in epithelial barrier integrity and function in a murine model
    Jui Chieh Chen
    Graduate Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei 100, Taiwan
    J Biol Chem 286:26667-79. 2011
    ..in response to continuous exposure to proteolytically active Pen c 13, a major allergen secreted by Penicillium citrinum...
  72. ncbi Chronic airway colonization by Penicillium emersonii in a patient with cystic fibrosis
    B Cimon
    Laboratoire de Parasitologie Mycologie, CHU, Angers, France
    Med Mycol 37:291-3. 1999
    b>Penicillium emersonii Stolk, the conidial state of Talaromyces emersoniii Stolk, is a heat-resistant fungus usually isolated from soil. In this paper the authors report, to our knowledge, the first human case in which P...
  73. pmc Molecular basis for mycophenolic acid biosynthesis in Penicillium brevicompactum
    Torsten Bak Regueira
    Department of Systems Biology, Technical University of Denmark, 2800 Kongens Lyngby, Denmark
    Appl Environ Microbiol 77:3035-43. 2011
    ..synthase (PKS), MpaC, which we successfully characterized and identified as responsible for MPA production in Penicillium brevicompactum...
  74. ncbi Characterization of the Penicillium chrysogenum antifungal protein PAF
    Lydia Kaiserer
    Department of Molecular Biology, University of Innsbruck, Fritz Pregl Strasse 3, 6020, Innsbruck, Austria
    Arch Microbiol 180:204-10. 2003
    The filamentous fungus Penicillium chrysogenum abundantly secretes the small, highly basic and cysteine-rich protein PAF ( Penicillium antifungal protein). In this study, the antifungal activity of PAF is described...
  75. ncbi Voriconazole as therapy for systemic Penicillium marneffei infections in AIDS patients
    Khuanchai Supparatpinyo
    Faculty of Medicine, Division of Infectious Disease, Chiang Mai University, 110 Intavaroros Road, Chiang Mai 50200, Thailand
    Am J Trop Med Hyg 77:350-3. 2007
    ..The objective of this study was to evaluate the triazole anti-fungal agent, voriconazole, as therapy for systemic Penicillium marneffei infections in patients with advanced HIV infection. Patients with systemic P...
  76. ncbi Purification, immobilization and characterization of tannase from Penicillium variable
    Shashi Sharma
    Department of Microbiology, University of Delhi South Campus, Benito Juarez Road, New Delhi 110 021, India
    Bioresour Technol 99:2544-51. 2008
    Tannase from Penicillium variable IARI 2031 was purified by a two-step purification strategy comprising of ultra-filtration using 100 kDa molecular weight cutoff and gel-filtration using Sephadex G-200...
  77. pmc Detection of cell wall mannoprotein Mp1p in culture supernatants of Penicillium marneffei and in sera of penicilliosis patients
    L Cao
    Department of Microbiology, The University of Hong Kong
    J Clin Microbiol 37:981-6. 1999
    ..The MP1 gene encodes a cell wall mannoprotein of the pathogenic fungus Penicillium marneffei...
  78. pmc Detection of specific antibodies to an antigenic mannoprotein for diagnosis of Penicillium marneffei penicilliosis
    L Cao
    Department of Microbiology, The University of Hong Kong
    J Clin Microbiol 36:3028-31. 1998
    The disseminated and progressive fungal disease Penicillium marneffei penicilliosis is one of the most common infectious diseases in AIDS patients in Southeast Asia...
  79. ncbi Citrinin dimers from the halotolerant fungus Penicillium citrinum B-57
    Zhen Yu Lu
    Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People s Republic of China
    J Nat Prod 71:543-6. 2008
    ..for structurally novel and bioactive natural compounds from microorganisms, a halotolerant fungal strain, Penicillium citrinum B-57, which mainly produces citrinin derivatives, was isolated from sediments collected from the ..
  80. pmc Versatile enzyme expression and characterization system for Aspergillus nidulans, with the Penicillium brevicompactum polyketide synthase gene from the mycophenolic acid gene cluster as a test case
    Bjarne G Hansen
    Technical University of Denmark, Department of Systems Biology, Center for Microbial Biotechnology, Building 223, 2800 Kgs Lyngby, Denmark
    Appl Environ Microbiol 77:3044-51. 2011
    ..We have demonstrated the potential of the system by transferring the 7,745-bp large mpaC gene from Penicillium brevicompactum to A. nidulans...
  81. pmc Role of Cannomys badius as a natural animal host of Penicillium marneffei in India
    Harish Gugnani
    Department of Medical Mycology, University of Delhi, India
    J Clin Microbiol 42:5070-5. 2004
    Infection by Penicillium marneffei in human immunodeficiency virus-positive patients in India has recently been described; the aim of our study was to survey wild rodents and their associated environment in order to identify the natural ..
  82. pmc Studies on the mode of action of the antifungal hexapeptide PAF26
    Alberto Munoz
    Instituto de Agroquímica y Tecnología de Alimentos IATA, Apartado de Correos 73, Burjassot, E 46100 Valencia, Spain
    Antimicrob Agents Chemother 50:3847-55. 2006
    ..In this work, we investigated the mode of action and inhibitory effects of PAF26 on the fungus Penicillium digitatum. The dye Sytox Green was used to demonstrate that PAF26 induced cell permeation...
  83. pmc Multilocus microsatellite typing system for Penicillium marneffei reveals spatially structured populations
    Matthew C Fisher
    Department of Infectious Disease Epidemiology, Imperial College Faculty of Medicine, London W2 1PG, UK
    J Clin Microbiol 42:5065-9. 2004
    ..Here, we describe the application of an MLMT system to the emerging pathogenic fungus Penicillium marneffei...
  84. doi Ambient pH stress inhibits spore germination of Penicillium expansum by impairing protein synthesis and folding: a proteomic-based study
    Boqiang Li
    Key Laboratory of Photosynthesis and Environmental Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China
    J Proteome Res 9:298-307. 2010
    ..In this study, effects of ambient pH on spore germination were determined by culturing spores of Penicillium expansum in medium with pH values at 2.0, 5.0 and 8...
  85. doi Influence of light on food relevant fungi with emphasis on ochratoxin producing species
    Markus Schmidt-Heydt
    Department for Safety and Quality of Fruit and Vegetables, Max Rubner Institut, Haid und Neu Str 9, 76131 Karlsruhe, Germany
    Int J Food Microbiol 145:229-37. 2011
    ..niger, A. steynii and on Penicillium nordicum and P. verrucosum was analysed...
  86. ncbi Genomic and experimental evidence for a potential sexual cycle in the pathogenic thermal dimorphic fungus Penicillium marneffei
    Patrick C Y Woo
    Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong
    FEBS Lett 580:3409-16. 2006
    ..fumigatus and Aspergillus nidulans and a putative MAT-1 alpha box mating-type gene were present in the Penicillium marneffei genome...
  87. ncbi Clinical presentations and outcomes of Penicillium marneffei infections: a series from 1994 to 2004
    T C Wu
    Department of Medicine, Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, Hong Kong
    Hong Kong Med J 14:103-9. 2008
    To describe the clinical presentation, management, and outcomes of patients with Penicillium marneffei infections in a regional hospital in Hong Kong.
  88. doi Penicillium marneffei infection presenting as an immune reconstitution inflammatory syndrome in an HIV patient
    A Ho
    The Infection, Tropical Medicine and Counselling Services, Brownlee Centre, Gartnavel General Hospital, Glasgow, UK
    Int J STD AIDS 21:780-2. 2010
    We describe a case of Penicillium marneffei infection acquired in Thailand, manifesting as an immune reconstitution inflammatory syndrome (IRIS) in a Caucasian man with advanced HIV-related immunosuppression (CD4 72 cells/mm³)...
  89. ncbi Toll-like receptor 2 (TLR2) and dectin-1 contribute to the production of IL-12p40 by bone marrow-derived dendritic cells infected with Penicillium marneffei
    Kiwamu Nakamura
    Department of Infection Control and Laboratory Diagnostics, Internal Medicine, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
    Microbes Infect 10:1223-7. 2008
    ..TLR4 and dectin-1 in the production of IL-12p40 by bone marrow-derived dendritic cells (BM-DCs) infected with Penicillium marneffei...
  90. ncbi Penicillium species endophytic in coffee plants and ochratoxin A production
    Fernando E Vega
    Insect Biocontrol Laboratory, US Department of Agriculture, Agricultural Research Service, BARC W, Beltsville, Maryland 20705, USA
    Mycologia 98:31-42. 2006
    ..DNA was extracted from a set of isolates visually recognized as Penicillium, and the internal transcribed spacer region and partial LSU-rDNA was amplified and sequenced...
  91. ncbi Development and evaluation of loop-mediated isothermal amplification (LAMP) for the rapid diagnosis of Penicillium marneffei in archived tissue samples
    Jiufeng Sun
    Department of Dermatology, The Second Affiliated Hospital, Sun Yat Sen University, Guangzhou, China
    FEMS Immunol Med Microbiol 58:381-8. 2010
    b>Penicillium marneffei is the etiologic agent of a severe systemic disease in immunocompromised hosts in Southeast Asia...
  92. ncbi Conidiation induction in Penicillium
    Tomás Roncal
    Unidad de Bioquímica 2, Facultad de Quimica, Universidad del Pais Vasco, PO Box 1072, 20080 San Sebastian, Spain
    Res Microbiol 154:539-46. 2003
    ..The aim of this review is to summarize the current advances in conidiation induction in the genus Penicillium, and to put them into context with the state of our knowledge stemming from work in widely studied fungal model ..
  93. ncbi Molecular analysis of two cytochrome P450 monooxygenase genes required for paxilline biosynthesis in Penicillium paxilli, and effects of paxilline intermediates on mammalian maxi-K ion channels
    L K McMillan
    Centre for Functional Genomics, Institute of Molecular Biosciences, College of Sciences, Massey University, Private Bag 11 222, Palmerston North, New Zealand
    Mol Genet Genomics 270:9-23. 2003
    The gene cluster required for paxilline biosynthesis in Penicillium paxilli contains two cytochrome P450 monooxygenase genes, paxP and paxQ...
  94. ncbi Efflux of organic acids in Penicillium simplicissimum is an energy-spilling process, adjusting the catabolic carbon flow to the nutrient supply and the activity of catabolic pathways
    Martin Gallmetzer
    Institute of Microbiology, Leopold Franzens University of Innsbruck, Technikerstrasse 25, 6020 Innsbruck, Austria
    Microbiology 148:1143-9. 2002
    ..ammonium, nitrate or phosphate limitation on the excretion of tricarboxylic acid (TCA) cycle intermediates by Penicillium simplicissimum...
  95. ncbi Delimitation of Penicillium virgatum sp. nov. and P. daleae on the basis of morphological and molecular characters
    Hanna Kwaśna
    Department of Forest Pathology, Agriculture University, ul Wojska Polskiego 71 c, 60 625 Poznan, Poland
    Mycol Res 109:974-82. 2005
    b>Penicillium virgatum sp. nov. is described from the soil of a soybean field in New Caledonia. Its delimitation from P. daleae, isolated from forest soils in Poland and Germany, is discussed...
  96. ncbi [A case of disseminated Penicillium marneffei infection in a liver transplant recipient]
    Ja Young Seo
    Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Korean J Lab Med 30:400-5. 2010
    b>Penicillium marneffei is the only dimorphic fungus among Penicillium spp. that can cause a fatal infection in immunocompromised patients. P. marneffei is endemic in Southeast Asia and eastern China. P...
  97. ncbi Novel bioactive breviane spiroditerpenoids from Penicillium brevicompactum Dierckx
    F A Macias
    Departamento de Quimica Organica, Facultad de Ciencias, Universidad de Cadiz, Apdo 40, 11510 Puerto Real, Cadiz, Spain
    J Org Chem 65:9039-46. 2000
    ..B, C, D, and E, potential allelopathic agents, have been determined from extracts of semisolid fermented Penicillium brevicompactum Dierckx. The structures display the novel breviane spiroditerpenoid skeleton...
  98. ncbi Comparison of modular and non-modular xylanases as carrier proteins for the efficient secretion of heterologous proteins from Penicillium funiculosum
    M J C Alcocer
    School of Life and Environmental Sciences, University of Nottingham, University Park, NG7 2RD, Nottingham
    Appl Microbiol Biotechnol 60:726-32. 2003
    Genes encoding three enzymes with xylanase activity from the filamentous fungus Penicillium funiculosum are described...
  99. ncbi Cycloaspeptide A and pseurotin A from the endophytic fungus Penicillium janczewskii
    Guillermo Schmeda-Hirschmann
    Laboratorio de Quimica de Productos Naturales, Instituto de Quimica de Recursos Naturales, Universidad de Talca, Casilla 747, Talca, Chile
    Z Naturforsch C 63:383-8. 2008
    b>Penicillium janczewskii K. M. Zalessky was isolated as an endophytic fungus from the phloem of the Chilean gymnosperm Prumnopitys andina...
  100. doi Gentisyl alcohol derivatives from the marine-derived fungus Penicillium terrestre
    Li Chen
    Key Laboratory of Marine Drugs, Chinese Ministry of Education, Institute of Marine Drugs and Food, Ocean University of China, Qingdao, People s Republic of China
    J Nat Prod 71:66-70. 2008
    ..derivative (12), together with four known analogues (9-11, 13) were isolated from the marine-derived fungus Penicillium terrestre...
  101. ncbi Cloning, characterization and differential expression of an hsp70 gene from the pathogenic dimorphic fungus, Penicillium marneffei
    Aksarakorn Kummasook
    Department of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
    DNA Seq 18:385-94. 2007
    A gene encoding heat shock protein 70 (Hsp70) of Penicillium marneffei was isolated and characterized. The structure of P...

Research Grants84

  1. CHEMICAL SYNTHESIS OF NOVEL NATURAL PRODUCTS
    David Williams; Fiscal Year: 1993
    ..2. Funiculosin: Novel Anti-Infective Cyclitols. Funiculosin is a structurally unique Penicillium metabolite, which displays antiviral and antitumor effects...
  2. STRUCTURES OF ANTIBIOTICS AND RELATED COMPOUNDS
    KENNETH RINEHART; Fiscal Year: 1999
    ..assays against Bacillus subtilis, Micrococcus luteus, Escherichia coli, Saccharomyces cerevisiae, and Penicillium atrovenetum...
  3. STRUCTURES OF ANTIBIOTICS AND RELATED COMPOUNDS
    KENNETH RINEHART; Fiscal Year: 1990
    ..assays against Bacillus subtilis, Micrococcus luteus, Escherichia coli, Saccharomyces cerevisiae, and Penicillium atrovenetum...
  4. Evolving Fungal Cell Surfaces: Characterization by AFM
    Sandra Bonetti; Fiscal Year: 2002
    ..subproject, titled Evolving Fungal Cell Surfaces: Characterization by Atomic Force Microscopy, the structure of Penicillium cell walls and wall remodeling processes will be investigated using a promising new instrument, the atomic ..
  5. Health Effects of CREON2000 In Asthmatic Children
    Mark Glazman; Fiscal Year: 2003
    ..will include air and settled dust samples to analyze allergens (dust mite, cat, dog, cockroach and Aspergillus, Penicillium, Cladosporium and Alternaria mold spores) and bacterial and endotoxin levels in the child's bedroom...
  6. Remediation Process for Aflatoxin Contaminated Foods
    ADRIAN DENVIR; Fiscal Year: 2002
    Mycotoxins are carcinogenic compounds that are produced by Aspergillus, Penicillium and Fusarium molds on agricultural produce and affect up to 25 per cent of the worlds food crops...
  7. Enantioselective Total Synthesis of Marcfortine B via SmI2-mediated C-C Bond Form
    TIMOTHY KUM BENG; Fiscal Year: 2012
    ..Marcfortines A, B, and C are fungal metabolites of Penicillium roqueforti. To date, an enantioselective synthesis of the marcfortines has not been reported...
  8. STEREOCHEMICAL STUDIES OF ISOPRENOID BIOSYNTHESIS
    DAVID CANE; Fiscal Year: 1992
    ..The latter enzyme has also been isolated by Dr. Hohn from Penicillium roquefortii and purified to homogeneity...
  9. STEREOCHEMICAL STUDIES OF ISOPRENOID BIOSYNTHESIS
    DAVID CANE; Fiscal Year: 1993
    ..The latter enzyme has also been isolated by Dr. Hohn from Penicillium roquefortii and purified to homogeneity...
  10. STEREOCHEMICAL STUDIES OF ISOPRENOID BIOSYNTHESIS
    DAVID CANE; Fiscal Year: 1991
    ..The latter enzyme has also been isolated by Dr. Hohn from Penicillium roquefortii and purified to homogeneity...
  11. STEREOCHEMICAL STUDIES OF ISOPRENOID BIOSYNTHESIS
    DAVID CANE; Fiscal Year: 1990
    ..The latter enzyme has also been isolated by Dr. Hohn from Penicillium roquefortii and purified to homogeneity...
  12. TAS::75 0862::TAS
    Martin D Chapman; Fiscal Year: 2010
    ..versicolor, Stachybotrys and Penicillium spp...
  13. Metabolic and Biosynthetic Engineering of Statin-Producing Filamentous Fungus
    Yi Tang; Fiscal Year: 2009
    ..a prolific producer of some of the most important drugs known to human kind, including penicillin from Penicillium notatum and the statins from Aspergillus species...
  14. Metabolic and Biosynthetic Engineering of Statin-Producing Filamentous Fungus
    Yi Tang; Fiscal Year: 2010
    ..a prolific producer of some of the most important drugs known to human kind, including penicillin from Penicillium notatum and the statins from Aspergillus species...
  15. CHARACTERIZATION OF ACID PHOSPHATASE FROM PENICILLIUM FELLUTANUM
    Sandra Bonetti; Fiscal Year: 1999
    ..of this subproject is to explore the hypothesis that a family of fungal acid phosphomonoesterase derived from Penicillium fellutanum are involved in the processing of glycopeptides from the membrane, cell wall, and extracellular ..
  16. CHARACTERIZATION OF ACID PHOSPHATASE FROM PENICILLIUM FELLUTANUM
    Sandra Bonetti; Fiscal Year: 2000
    ..of this subproject is to explore the hypothesis that a family of fungal acid phosphomonoesterase derived from Penicillium fellutanum are involved in the processing of glycopeptides from the membrane, cell wall, and extracellular ..
  17. CHARACTERIZATION OF ACID PHOSPHATASE FROM PENICILLIUM FELLUTANUM
    Sandra Bonetti; Fiscal Year: 1999
    ..of this subproject is to explore the hypothesis that a family of fungal acid phosphomonoesterase derived from Penicillium fellutanum are involved in the processing of glycopeptides from the membrane, cell wall, and extracellular ..
  18. CHARACTERIZATION OF ACID PHOSPHATASE FROM PENICILLIUM FELLUTANUM
    Sandra Bonetti; Fiscal Year: 2001
    ..of this subproject is to explore the hypothesis that a family of fungal acid phosphomonoesterase derived from Penicillium fellutanum are involved in the processing of glycopeptides from the membrane, cell wall, and extracellular ..
  19. Inhibitors of transcription of fungal glucan synthase
    Claude Selitrennikoff; Fiscal Year: 2003
    ..at least in the ascomycetes, and appears to be very similar in human pathogens including Candida albicans, Penicillium spp., and Aspergillus spp...
  20. MBRS
    Sandra Bonetti; Fiscal Year: 1993
    This project proposes to examine the structures of low and high molecular weight mycelial glycopeptides from Penicillium charlesii and to determine whether these polymers serve as precursors and/or points of attachment or anchors for ..
  21. NEW TECHNIQUES IN RAMAN SPECTROSCOPY OF BIO-MOLECULES
    FRED LYTLE; Fiscal Year: 1980
    ..This will be followed by studies of the melting of penicillium chrysogenum mycophage RNA and calf thymus DNA...
  22. BIOSYNTHESIS OF PARAHERQUAMIDES & BREVIANAMIDES
    Robert Williams; Fiscal Year: 2000
    ..159g The paraherquamides are complex, heptacyclic, toxic mold metabolites, isolated from various Penicillium sp...
  23. DNA DAMAGE AND MUTAGENICITY OF OCHRATOXIN A
    Richard Manderville; Fiscal Year: 2001
    ..OTA is a mycotoxin produced by several species of Aspergillus and Penicillium fungi. It is widely found in food products, particularly in northern climates of Europe and North America...
  24. DNA DAMAGE AND MUTAGENICITY OF OCHRATOXIN A
    Richard Manderville; Fiscal Year: 2000
    ..OTA is a mycotoxin produced by several species of Aspergillus and Penicillium fungi. It is widely found in food products, particularly in northern climates of Europe and North America...
  25. DNA DAMAGE AND MUTAGENICITY OF OCHRATOXIN A
    Richard Manderville; Fiscal Year: 2002
    ..OTA is a mycotoxin produced by several species of Aspergillus and Penicillium fungi. It is widely found in food products, particularly in northern climates of Europe and North America...
  26. DNA DAMAGE AND MUTAGENICITY OF OCHRATOXIN A
    Richard Manderville; Fiscal Year: 2001
    ..OTA is a mycotoxin produced by several species of Aspergillus and Penicillium fungi. It is widely found in food products, particularly in northern climates of Europe and North America...
  27. DNA DAMAGE AND MUTAGENICITY OF OCHRATOXIN A
    Richard Manderville; Fiscal Year: 2002
    ..OTA is a mycotoxin produced by several species of Aspergillus and Penicillium fungi. It is widely found in food products, particularly in northern climates of Europe and North America...
  28. CRYSTALLOGRAPHIC STUDIES OF PENICILLOPEPSIN
    I NAN HSU; Fiscal Year: 1980
    ..in terms of the refined three-dimensional structure of penicillo-pepsin (an extracellular acid protease from Penicillium zanthinellum) and structural details of the way in which penicillopsin interacts with its substrates, ..
  29. RADIOGAS CHROMATOGRAPH/QUADRUPOLE MASS SPECTROMETRY
    Iain Campbell; Fiscal Year: 1980
    ..The first, chosen for its ease of manipulation, involves an aspect of secondary metabolism in Penicillium patulum. 6-Methylsalicylic acid (6-MSA) and the mycotoxin, patulin, are produced by this organism...
  30. SEQUENCE-DEPENDENCE OF POLYNUCLEOTIDE CONFORMATION-III
    DONALD GRAY; Fiscal Year: 1980
    ..as a basis for analyzing the CD spectra of natural double-stranded RNAs from the virus particles of the fungus Penicillium chrysogenum and from phi6 Pseudomonas bacteriophage...
  31. MINORITY BIOMEDICAL SUPPORT
    GABRIEL INFANTE; Fiscal Year: 1980
    ..The last project studies the effect of temperature on selected permeases (sulfate, methionine, gucose) of specific thermophilic (Penicillium duponti) and mesophilic Penicillium chrysogenum) fungi.
  32. ENZYMOLOGY OF SULFATE ACTIVATION AND TRANSFER
    IRWIN SEGEL; Fiscal Year: 1980
    ..Major emphasis will be on ATP-sulfurylase and APS-kinase from Penicillium chrysogenum...
  33. Taxol Production with a Novel Fermentation Reactor
    TODD MCADAMS; Fiscal Year: 2002
    ..The ultimate objective is a commercially viable route to Taxol based on an optimized strain of Penicillium raistrickii, an optimized fermentation protocol and a high-intensity, low shear fermentation reactor...
  34. SUPPRESSION OF ESTABLISHED LEUKEMIA VIRUS INFECTIONS
    E Wheelock; Fiscal Year: 1980
    ..in infected mice with a single injection of double stranded RNA from statolon, an extract of mycophage-infected penicillium stoloniferum...
  35. FUNGAL GLYCOPEPTIDE BIOSYNTHESIS
    JOHN GANDER; Fiscal Year: 1980
    ..and biosynthesis of a membrane-bound lipo-peptidophosphogalactomannan, lipo-pPGM, from a species of Penicillium. Work proposed for the coming year is divided into three categories: 1) characterization of lipo-pPGM and ..
  36. LEUCOGENENOL
    DONALD ABERHART; Fiscal Year: 1980
    A reexamination of the structure of leucogenenol and a study of the biosynthesis of leucogenenol in mammalian thymus tissues and in Penicillium gilmanii is proposed.
  37. SYNTHESIS OF BIOLOGICALLY ACTIVE NATURAL PRODUCTS
    BARRY SNIDER; Fiscal Year: 2003
    ..The mechanism and synthetic utility of these cyclizations will be developed. ..
  38. Structure of Microsomal Enzymes in Estrogen Biosynthesis
    Debashis Ghosh; Fiscal Year: 2003
    ....
  39. Structure of Microsomal Enzymes in Estrogen Biosynthesis
    Debashis Ghosh; Fiscal Year: 2004
    ....
  40. SYNTHESIS OF BIOLOGICALLY ACTIVE NATURAL PRODUCTS
    BARRY SNIDER; Fiscal Year: 2005
    ..The mechanism and synthetic utility of these cyclizations will be developed. ..
  41. SYNTHESIS OF BIOLOGICALLY ACTIVE NATURAL PRODUCTS
    BARRY SNIDER; Fiscal Year: 2006
    ..In the course of these studies new methods will be developed that are of general utility for preparing drugs more economically. [unreadable] [unreadable]..
  42. Structure of Microsomal Enzymes in Estrogen Biosynthesis
    Debashis Ghosh; Fiscal Year: 2005
    ....
  43. SYNTHESIS OF BIOLOGICALLY ACTIVE NATURAL PRODUCTS
    BARRY SNIDER; Fiscal Year: 2008
    ..In the course of these studies new methods will be developed that are of general utility for preparing drugs more economically. ..
  44. SYNTHESIS OF BIOLOGICALLY ACTIVE NATURAL PRODUCTS
    BARRY SNIDER; Fiscal Year: 2009
    ..In the course of these studies new methods will be developed that are of general utility for preparing drugs more economically. ..
  45. SYNTHESIS OF BIOLOGICALLY ACTIVE NATURAL PRODUCTS
    BARRY SNIDER; Fiscal Year: 2007
    ..In the course of these studies new methods will be developed that are of general utility for preparing drugs more economically. [unreadable] [unreadable]..
  46. Structure of Microsomal Enzymes in Estrogen Biosynthesis
    Debashis Ghosh; Fiscal Year: 2002
    ....
  47. SYNTHESIS OF BIOLOGICALLY ACTIVE NATURAL PRODUCTS
    BARRY SNIDER; Fiscal Year: 2001
    ..8-1.1 mg/mL. The key step in this synthesis is the intramolecular Diels-Alder reaction of trienyl glyoxylate 192 to give 191 and stereoisomers. ..
  48. SYNTHESIS OF BIOLOGICALLY ACTIVE NATURAL PRODUCTS
    BARRY SNIDER; Fiscal Year: 2004
    ..The mechanism and synthetic utility of these cyclizations will be developed. ..
  49. SYNTHESIS OF BIOLOGICALLY ACTIVE NATURAL PRODUCTS
    BARRY SNIDER; Fiscal Year: 2002
    ..The mechanism and synthetic utility of these cyclizations will be developed. ..
  50. SYNTHESIS OF BIOLOGICALLY ACTIVE NATURAL PRODUCTS
    BARRY SNIDER; Fiscal Year: 1999
    ..8-1.1 mg/mL. The key step in this synthesis is the intramolecular Diels-Alder reaction of trienyl glyoxylate 192 to give 191 and stereoisomers. ..
  51. SYNTHESIS OF BIOLOGICALLY ACTIVE NATURAL PRODUCTS
    BARRY SNIDER; Fiscal Year: 2000
    ..8-1.1 mg/mL. The key step in this synthesis is the intramolecular Diels-Alder reaction of trienyl glyoxylate 192 to give 191 and stereoisomers. ..
  52. SYNTHESIS OF MACROCYCLES STEROIDS CYCLOPENTANOIDS ETC
    BARRY TROST; Fiscal Year: 2000
    ..Ring expansion methods may convert these cores into the taxoid skeleton with appropriate functionality at key points for analog development. ..
  53. SYNTHESIS OF CHLOROPEPTINS, GP120 CD4 BINDING INHIBITORS
    AMOS SMITH; Fiscal Year: 2000
    ..abstract_text> ..
  54. REDUCED DRUG INTERACTIONS OF AZOLE ANTIFUNGAL DRUGS
    Joseph Gal; Fiscal Year: 2002
    ..abstract_text> ..
  55. Biosynthesis of Microbial Polyketides
    DAVID CANE; Fiscal Year: 2007
    ..In addition, the results obtained will provide fundamental insights into how catalysis and molecular recognition control both substrate specificity and product molecular diversity in Nature. ..
  56. Phagocytosis-Pulmonary Alveolar Macrophages
    THOMAS STOSSEL; Fiscal Year: 2008
    ..The research plan is to define the chemistry of one of these parts in sufficient detail to enable future development of drugs to ameliorate such diseases. ..
  57. Phagocytosis-Pulmonary Alveolar Macrophages
    THOMAS STOSSEL; Fiscal Year: 2009
    ..The research plan is to define the chemistry of one of these parts in sufficient detail to enable future development of drugs to ameliorate such diseases. ..
  58. BIOLOGY OF VASCULAR, LUNG AND BLOOD DISEASES
    THOMAS STOSSEL; Fiscal Year: 2008
    ..End of Abstract) ..
  59. Phagocytosis-Pulmonary Alveolar Macrophages
    Thomas Peter Stossel; Fiscal Year: 2010
    ..The research plan is to define the chemistry of one of these parts in sufficient detail to enable future development of drugs to ameliorate such diseases. ..
  60. REDUCED DRUG INTERACTIONS OF AZOLE ANTIFUNGAL DRUGS
    Joseph Gal; Fiscal Year: 2001
    ..abstract_text> ..
  61. PHAGOCYTOSIS--PULMONARY ALVEOLAR MACROPHAGES
    THOMAS STOSSEL; Fiscal Year: 2007
    ..abstract_text> ..
  62. PHAGOCYTOSIS--PULMONARY ALVEOLAR MACROPHAGES
    THOMAS STOSSEL; Fiscal Year: 2002
    ..The eventual goal is to understand these processes sufficiently to modify them in hopes of mollifying inflammation and metastatic tumor spread. ..
  63. PHAGOCYTOSIS--PULMONARY ALVEOLAR MACROPHAGES
    THOMAS STOSSEL; Fiscal Year: 2001
    ..The eventual goal is to understand these processes sufficiently to modify them in hopes of mollifying inflammation and metastatic tumor spread. ..
  64. REDUCED DRUG INTERACTIONS OF AZOLE ANTIFUNGAL DRUGS
    Joseph Gal; Fiscal Year: 2003
    ..abstract_text> ..
  65. REDUCED DRUG INTERACTIONS OF AZOLE ANTIFUNGAL DRUGS
    Joseph Gal; Fiscal Year: 2000
    ..abstract_text> ..
  66. PHAGOCYTOSIS--PULMONARY ALVEOLAR MACROPHAGES
    THOMAS STOSSEL; Fiscal Year: 2000
    ..The eventual goal is to understand these processes sufficiently to modify them in hopes of mollifying inflammation and metastatic tumor spread. ..
  67. PHAGOCYTOSIS--PULMONARY ALVEOLAR MACROPHAGES
    THOMAS STOSSEL; Fiscal Year: 2003
    ..The eventual goal is to understand these processes sufficiently to modify them in hopes of mollifying inflammation and metastatic tumor spread. ..
  68. PHAGOCYTOSIS--PULMONARY ALVEOLAR MACROPHAGES
    THOMAS STOSSEL; Fiscal Year: 2004
    ..abstract_text> ..
  69. PHAGOCYTOSIS--PULMONARY ALVEOLAR MACROPHAGES
    THOMAS STOSSEL; Fiscal Year: 2005
    ..abstract_text> ..
  70. PHAGOCYTOSIS--PULMONARY ALVEOLAR MACROPHAGES
    THOMAS STOSSEL; Fiscal Year: 2006
    ..abstract_text> ..
  71. PHAGOCYTOSIS--PULMONARY ALVEOLAR MACROPHAGES
    THOMAS STOSSEL; Fiscal Year: 1999
    ..The eventual goal is to understand these processes sufficiently to modify them in hopes of mollifying inflammation and metastatic tumor spread. ..
  72. BIOLOGY OF VASCULAR, LUNG AND BLOOD DISEASES
    THOMAS STOSSEL; Fiscal Year: 2007
    ..End of Abstract) ..