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Genomes and GenesSpecies | wolbachiaSummarySummary: A genus of bacteria comprised of a heterogenous group of gram-negative small rods and coccoid forms associated with arthropods. (From Bergey's Manual of Systematic Bacteriology, vol 1, 1984) Top Publications
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A Wolbachia symbiont in Aedes aegypti limits infection with dengue, Chikungunya, and PlasmodiumLuciano A Moreira
School of Biological Sciences, The University of Queensland, Brisbane QLD 4072, Australia
Cell 139:1268-78. 2009b>Wolbachia are maternally inherited intracellular bacterial symbionts that are estimated to infect more than 60% of all insect species...
How many species are infected with Wolbachia?--A statistical analysis of current dataKirsten Hilgenboecker
Institute for Theoretical Biology, Humboldt University Berlin, Berlin, Germany
FEMS Microbiol Lett 281:215-20. 2008b>Wolbachia are intracellular bacteria found in many species of arthropods and nematodes...
Immune activation by life-shortening Wolbachia and reduced filarial competence in mosquitoesZakaria Kambris
Peter Medawar Building for Pathogen Research and Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
Science 326:134-6. 2009b>Wolbachia strain wMelPop reduces the longevity of its Drosophila melanogaster host and, when introduced into the mosquito Aedes aegypti, halves its life span...
Wolbachia stimulates immune gene expression and inhibits plasmodium development in Anopheles gambiaeZakaria Kambris
Department of Zoology, University of Oxford, Peter Medawar Building for Pathogen Research, Oxford, United Kingdom
PLoS Pathog 6:e1001143. 2010The over-replicating wMelPop strain of the endosymbiont Wolbachia pipientis has recently been shown to be capable of inducing immune upregulation and inhibition of pathogen transmission in Aedes aegypti mosquitoes...
Wolbachia: master manipulators of invertebrate biologyJohn H Werren
Biology Department, University of Rochester, Rochester, New York, New York 14627, USA
Nat Rev Microbiol 6:741-51. 2008b>Wolbachia are common intracellular bacteria that are found in arthropods and nematodes...
The endosymbiotic bacterium Wolbachia induces resistance to dengue virus in Aedes aegyptiGuowu Bian
Department of Entomology and Genetics Program, Michigan State University, East Lansing, Michigan, United States of America
PLoS Pathog 6:e1000833. 2010..The endosymbiotic bacterium Wolbachia has long been promoted as a potential vehicle for introducing disease-resistance genes into mosquitoes, thereby ..
Complete WO phage sequences reveal their dynamic evolutionary trajectories and putative functional elements required for integration into the Wolbachia genomeKohjiro Tanaka
National Institute of Advanced Industrial Science and Technology AIST, 1 1 1 Higashi, Tsukuba 305 8566, Japan
Appl Environ Microbiol 75:5676-86. 2009b>Wolbachia endosymbionts are ubiquitously found in diverse insects including many medical and hygienic pests, causing a variety of reproductive phenotypes, such as cytoplasmic incompatibility, and thereby efficiently spreading in host ..
Wolbachia: more than just a bug in insects genitalsAggeliki Saridaki
Department of Environmental and Natural Resources Management, University of Ioannina, Agrinio, Greece
Curr Opin Microbiol 13:67-72. 2010Research on the intracellular bacterial symbiont Wolbachia has grown on many levels, providing interesting insights on various aspects of the microbe's biology...
The native Wolbachia endosymbionts of Drosophila melanogaster and Culex quinquefasciatus increase host resistance to West Nile virus infectionRobert L Glaser
Wadsworth Center, New York State Department of Health, Albany, New York, United States of America
PLoS ONE 5:e11977. 2010The bacterial endosymbiont Wolbachia pipientis has been shown to increase host resistance to viral infection in native Drosophila hosts and in the normally Wolbachia-free heterologous host Aedes aegypti when infected by Wolbachia from ..
Complete bacteriophage transfer in a bacterial endosymbiont (Wolbachia) determined by targeted genome captureBethany N Kent
Department of Biological Sciences, Vanderbilt University, USA
Genome Biol Evol 3:209-18. 2011..as single genes or larger regions between coinfections, we sequenced the genome of the obligate intracellular Wolbachia strain wVitB from the parasitic wasp Nasonia vitripennis and compared it against the prophage sequences of the ..
The mosaic genome structure of the Wolbachia wRi strain infecting Drosophila simulansLisa Klasson
Department of Molecular Evolution, Evolutionary Biology Centre, Uppsala University, SE 752 36 Uppsala, Sweden
Proc Natl Acad Sci U S A 106:5725-30. 2009The obligate intracellular bacterium Wolbachia pipientis infects around 20% of all insect species...
Extensive genomic diversity of closely related Wolbachia strainsNadeeza Ishmael
J Craig Venter Institute, 9708 Medical Center Dr, Rockville, MD 20850, USA
Microbiology 155:2211-22. 2009Using microarray-based comparative genome hybridization (mCGH), the genomic content of Wolbachia pipientis wMel from Drosophila melanogaster was compared to the closely related Wolbachia from D. innubila (wInn), D...
Phage WO of Wolbachia: lambda of the endosymbiont worldBethany N Kent
Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA
Trends Microbiol 18:173-81. 2010The discovery of an extraordinarily high level of mobile elements in the genome of Wolbachia, a widespread arthropod and nematode endosymbiont, suggests that this bacterium could be an excellent model for assessing the evolution and ..
Genome evolution of Wolbachia strain wPip from the Culex pipiens groupLisa Klasson
Peter Medawar Building for Pathogen Research and Department of Zoology, University of Oxford, Oxford, United Kingdom
Mol Biol Evol 25:1877-87. 2008The obligate intracellular bacterium Wolbachia pipientis strain wPip induces cytoplasmic incompatibility (CI), patterns of crossing sterility, in the Culex pipiens group of mosquitoes. The complete sequence is presented of the 1...
Variation in antiviral protection mediated by different Wolbachia strains in Drosophila simulansSheree E Osborne
School of Biological Sciences, The University of Queensland, St Lucia, Queensland, Australia
PLoS Pathog 5:e1000656. 2009..The Drosophila host is also commonly infected with the widespread endosymbiotic bacteria Wolbachia pipientis. When DCV coinfects Wolbachia-infected D...
Isolation and characterization of the bacteriophage WO from Wolbachia, an arthropod endosymbiontYukiko Fujii
Department of Biological Sciences, Graduate School of Science, University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
Biochem Biophys Res Commun 317:1183-8. 2004b>Wolbachia is a group of obligate symbiotic bacteria found in many insects and other arthropods. The presence of Wolbachia alters reproduction in the host, but the mechanisms are unknown...
Wolbachia-mediated cytoplasmic incompatibility is associated with impaired histone deposition in the male pronucleusFrédéric Landmann
Department of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, USA
PLoS Pathog 5:e1000343. 2009b>Wolbachia is a bacteria endosymbiont that rapidly infects insect populations through a mechanism known as cytoplasmic incompatibility (CI)...
Asymmetric Wolbachia segregation during early Brugia malayi embryogenesis determines its distribution in adult host tissuesFrédéric Landmann
Department of Molecular, Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America
PLoS Negl Trop Dis 4:e758. 2010b>Wolbachia are required for filarial nematode survival and fertility and contribute to the immune responses associated with human filarial diseases...
Stable introduction of a life-shortening Wolbachia infection into the mosquito Aedes aegyptiConor J McMeniman
School of Integrative Biology, University of Queensland, Brisbane 4072, Australia
Science 323:141-4. 2009..The successful transfer of a life-shortening strain of the inherited bacterial symbiont, Wolbachia, into the major mosquito vector of dengue, Aedes aegypti, halved adult life span under laboratory conditions...
Wolbachia and virus protection in insectsLauren M Hedges
School of Integrative Biology, University of Queensland, Brisbane 4072, Australia
Science 322:702. 2008b>Wolbachia pipientis bacteria are common endosymbionts of insects that are best known for their ability to increase their prevalence in populations by manipulating host reproductive systems...
The tripartite associations between bacteriophage, Wolbachia, and arthropodsSeth R Bordenstein
Josephine Bay Paul Center for Comparative Molecular Biology and Evolution, The Marine Biological Laboratory, Woods Hole, Massachusetts, USA
PLoS Pathog 2:e43. 2006By manipulating arthropod reproduction worldwide, the heritable endosymbiont Wolbachia has spread to pandemic levels...
Wolbachia distribution and cytoplasmic incompatibility during sperm development: the cyst as the basic cellular unit of CI expressionMichael E Clark
Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL 60637, USA
Mech Dev 120:185-98. 2003The growth and distribution of the intracellular microbe Wolbachia pipientis during spermatogenesis in several different host/symbiont genetic combinations in Drosophila melanogaster and Drosophila simulans is described...
The genetics and cell biology of Wolbachia-host interactionsLaura R Serbus
Molecular, Cell and Developmental Biology, University of California, Santa Cruz, California 95064, USA
Annu Rev Genet 42:683-707. 2008b>Wolbachia are gram-negative bacteria that are widespread in nature, carried by the majority of insect species as well as some mites, crustaceans, and filarial nematodes...
Bacteriophage flux in endosymbionts (Wolbachia): infection frequency, lateral transfer, and recombination ratesSeth R Bordenstein
The Marine Biological Laboratory, Josephine Bay Paul Center for Comparative Molecular Biology and Evolution, Woods Hole, Massachusetts, USA
Mol Biol Evol 21:1981-91. 2004..been influential in the genome evolution of the most prevalent bacterial endosymbiont of invertebrates, Wolbachia. First, we show that bacteriophage WO is more widespread in Wolbachia than previously recognized, occurring in ..
Increased locomotor activity and metabolism of Aedes aegypti infected with a life-shortening strain of Wolbachia pipientisOliver Evans
School of Biological Sciences, The University of Queensland, St Lucia, Queensland, 4072, Australia
J Exp Biol 212:1436-41. 2009A virulent strain of the obligate intracellular bacterium Wolbachia pipientis that shortens insect lifespan has recently been transinfected into the primary mosquito vector of dengue virus, Aedes aegypti L...
The bacterial symbiont Wolbachia induces resistance to RNA viral infections in Drosophila melanogasterLuis Teixeira
Department of Genetics, University of Cambridge, Cambridge, United Kingdom
PLoS Biol 6:e2. 2008b>Wolbachia are vertically transmitted, obligatory intracellular bacteria that infect a great number of species of arthropods and nematodes...
An endosymbiotic bacterium in a plant-parasitic nematode: member of a new Wolbachia supergroupAnnelies Haegeman
Department of Molecular Biotechnology, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium
Int J Parasitol 39:1045-54. 2009b>Wolbachia is an endosymbiotic bacterium widely present in arthropods and animal-parasitic nematodes. Despite previous efforts, it has never been identified in plant-parasitic nematodes...
Remarkable abundance and evolution of mobile group II introns in Wolbachia bacterial endosymbiontsSébastien Leclercq
Centre National de la Recherche Scientifique UMR 6556 Ecologie, Evolution, Symbiose, Universite de Poitiers, Poitiers, France
Mol Biol Evol 28:685-97. 2011..Yet, the genomes of Wolbachia, one of the most abundant bacterial endosymbionts on Earth, are littered with transposable elements, in ..
Widespread lateral gene transfer from intracellular bacteria to multicellular eukaryotesJulie C Dunning Hotopp
Institute for Genomic Research, J Craig Venter Institute, 9712 Medical Center Drive, Rockville, MD 20850, USA
Science 317:1753-6. 2007..However, the presence of endosymbionts, such as Wolbachia pipientis, within some eukaryotic germlines may facilitate bacterial gene transfers to eukaryotic host genomes...
Strain-specific regulation of intracellular Wolbachia density in multiply infected insectsL Mouton
Laboratoire de Biometrie et Biologie Evolutive, Universite Claude Bernard, 43 Boulevard du 11 Novembre 1918, 69622 Villeurbanne Cedex, France
Mol Ecol 12:3459-65. 2003..b>Wolbachia endosymbionts that induce cytoplasmic incompatibility in their hosts depart from this rule, because cytoplasmic ..
Diversity, distribution and specificity of WO phage infection in Wolbachia of four insect speciesL Gavotte
Laboratoire de Biometrie et Biologie Evolutive, Université Lyon I CNRS, Villeurbanne, France
Insect Mol Biol 13:147-53. 2004The bacteriophage WO was recently characterized in Wolbachia, a strictly intracellular bacterium that causes several reproductive alterations in its arthropod hosts...
Functional conservation of the lipid II biosynthesis pathway in the cell wall-less bacteria Chlamydia and Wolbachia: why is lipid II needed?Beate Henrichfreise
Institute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany
Mol Microbiol 73:913-23. 2009..Genes for enzymes of both machineries have been found in the genomes of the cell wall-less genera Chlamydia and Wolbachia, raising questions as to the functionality of the lipid II biosynthesis pathway and reasons for its conservation...
Wolbachia infection frequencies in insects: evidence of a global equilibrium?J H Werren
Department of Biology, University of Rochester, NY 14627, USA
Proc Biol Sci 267:1277-85. 2000b>Wolbachia are a group of cytoplasmically inherited bacteria that cause reproduction alterations in arthropods, including parthenogenesis, reproductive incompatibility, feminization of genetic males and male killing...
Wolbachia pipientis: an expanding bag of tricks to explore for disease controlPeter E Cook
School of Biological Sciences, The University of Queensland, Brisbane, Australia
Trends Parasitol 26:373-5. 2010b>Wolbachia pipientis are maternally inherited, endosymbiotic bacteria that are widespread among insects...
Symbiont genes in host genomes: fragments with a future?Mark Blaxter
Institute of Evolutionary Biology, School of Biological Sciences, Ashworth Laboratories, King s Buildings, University of Edinburgh, West Mains Road, Edinburgh, Scotland EH9 3JT, UK
Cell Host Microbe 2:211-3. 2007..Germline-transmitted animal symbionts, such as Wolbachia pipientis, are well placed to participate in such transfers. In a recent issue of Science, Dunning Hotopp et al...
Wolbachia as a bacteriocyte-associated nutritional mutualistTakahiro Hosokawa
National Institute of Advanced Industrial Science and Technology, Tsukuba 305 8566, Japan
Proc Natl Acad Sci U S A 107:769-74. 2010..Facultative and parasitic bacterial symbionts like Wolbachia have been regarded as evolutionarily distinct from such obligate nutritional mutualists...
Wolbachia-induced cytoplasmic incompatibility as a means for insect pest population controlSofia Zabalou
Department of Medical Sciences, Medical School, University of Crete, Heraklion 711 10, Crete, Greece
Proc Natl Acad Sci U S A 101:15042-5. 2004..b>Wolbachia are inherited bacteria of arthropods that have recently attracted attention for their potential as new ..
Human probing behavior of Aedes aegypti when infected with a life-shortening strain of WolbachiaLuciano A Moreira
School of Biological Sciences, The University of Queensland, St Lucia, Queensland, Australia
PLoS Negl Trop Dis 3:e568. 2009..Alternative strategies include the proposed use of inherited life-shortening agents, such as the Wolbachia bacterium...
The genome of Brugia malayi - all worms are not created equalAlan L Scott
Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Parasitol Int 58:6-11. 2009..genetic basis for mutualism, as Brugia, like a majority of filarial species, harbors an endosybiotic bacterium (Wolbachia)...
Multiple rescue factors within a Wolbachia strainSofia Zabalou
Institute of Molecular Biology and Biotechnology, FORTH, Vassilika Vouton, Heraklion 71110, Crete, Greece
Genetics 178:2145-60. 2008b>Wolbachia-induced cytoplasmic incompatibility (CI) is expressed when infected males are crossed with either uninfected females or females infected with Wolbachia of different CI specificity...
Long PCR improves Wolbachia DNA amplification: wsp sequences found in 76% of sixty-three arthropod speciesA Jeyaprakash
Department of Entomology and Nematology, University of Florida, Gainesville, Florida 32611, USA
Insect Mol Biol 9:393-405. 2000Bacteria belonging to the genus Wolbachia are associated with a variety of reproductive anomalies in arthropods. Allele-specific polymerase chain reaction (= Standard PCR) routinely has been used to amplify Wolbachia DNA from arthropods...
Intense transpositional activity of insertion sequences in an ancient obligate endosymbiontRichard Cordaux
CNRS UMR 6556 Ecologie, Evolution, Symbiose, Universite de Poitiers, Poitiers, France
Mol Biol Evol 25:1889-96. 2008..Yet, the genome of Wolbachia, one of the most abundant bacterial endosymbionts on Earth, is littered with IS...
Endosymbiont DNA in endobacteria-free filarial nematodes indicates ancient horizontal genetic transferSamantha N McNulty
Infectious Diseases Division, Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri, USA
PLoS ONE 5:e11029. 2010b>Wolbachia are among the most abundant symbiotic microbes on earth; they are present in about 66% of all insect species, some spiders, mites and crustaceans, and most filarial nematode species...
Pathogenesis and host responses in human onchocerciasis: impact of Onchocerca filariae and Wolbachia endobacteriaN W Brattig
Tropical Medicine Section, Bernhard Nocht Institute for Tropical Medicine, Bernhard Nocht Strasse 74, 20359, Hamburg, Germany
Microbes Infect 6:113-28. 2004..The filariae habour abundant intracellular Wolbachia bacteria, now recognised as obligatory symbionts, and therefore emerging as a novel target for chemotherapy...
A Survey of the bacteriophage WO in the endosymbiotic bacteria WolbachiaLaurent Gavotte
Laboratoire de Biométrie et Biologie Évolutive UMR 5558, CNRS, IFR 41, University Lyon 1, Villeurbanne, France
Mol Biol Evol 24:427-35. 2007..However, Wolbachia, an intracellular alpha-proteobacterium, infecting diverse arthropod and nematode species and best known for the ..
ISWpi1 from Wolbachia pipientis defines a novel group of insertion sequences within the IS5 familyRichard Cordaux
Laboratoire de Génétique et Biologie des Populations de Crustacés, CNRS UMR 6556, Universite de Poitiers, 40 Avenue du Recteur Pineau, 86022 Poitiers, France
Gene 409:20-7. 2008..which the taxonomic distribution appears to be restricted to the obligate intracellular alpha-Proteobacterium Wolbachia pipientis...
Bacteriophage WO and virus-like particles in Wolbachia, an endosymbiont of arthropodsS Masui
Department of Biological Sciences, Graduate School of Science, University of Tokyo, Hongo, Bunkyo ku, Tokyo, 113 0033, Japan
Biochem Biophys Res Commun 283:1099-104. 2001b>Wolbachia are intracellular symbionts mainly found in arthropods, causing various sexual alterations on their hosts by unknown mechanisms...
Somatic stem cell niche tropism in WolbachiaHoracio M Frydman
Howard Hughes Medical Institute, Princeton University, Princeton, New Jersey 08540, USA
Nature 441:509-12. 2006b>Wolbachia are intracellular bacteria found in the reproductive tissue of all major groups of arthropods. They are transmitted vertically from the female hosts to their offspring, in a pattern analogous to mitochondria inheritance...
The rate of recombination in Wolbachia bacteriaFrancis M Jiggins
Department of Genetics, University of Cambridge, UK
Mol Biol Evol 19:1640-3. 2002
Antibiotics and Wolbachia in filarial nematodes: antifilarial activity of rifampicin, oxytetracycline and chloramphenicol against Onchocerca gutturosa, Onchocerca lienalis and Brugia pahangiS Townson
Tropical Parasitic Diseases Unit, Northwick Park Institute for Medical Research, Harrow, UK
Ann Trop Med Parasitol 94:801-16. 2000..to study the effects of rifampicin and oxytetracycline on filarial tissues and on the endosymbiont bacterium, Wolbachia. When tested in vitro at a concentration of 50...
Parasitism and mutualism in Wolbachia: what the phylogenomic trees can and cannot saySeth R Bordenstein
Josephine Bay Paul Center, Marine Biological Laboratory, Woods Hole, MA, USA
Mol Biol Evol 26:231-41. 2009..b>Wolbachia is an inherited obligate, intracellular infection of invertebrates containing taxa that act broadly as both ..
Coexistence of Wolbachia with Buchnera aphidicola and a secondary symbiont in the aphid Cinara cedriLaura Gomez-Valero
Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de Valencia, Valencia, Spain
J Bacteriol 186:6626-33. 2004..previously found to be associated with aphids (PASS, or R type) and an alpha-proteobacterium that belongs to the Wolbachia genus...
Wolbachia-based technologies for insect pest population controlKostas Bourtzis
Department of Environmental and Natural Resources Management, University of Ioannina, 30100 Agrinio, Greece
Adv Exp Med Biol 627:104-13. 2008b>Wolbachia are a group of obligatory intracellular and maternally inherited bacteria found in many arthropod species, including insects, mites, spiders, springtails, crustaceans, as well as in certain nematodes...
Wolbachia-induced unidirectional cytoplasmic incompatibility and speciation: mainland-island modelArndt Telschow
Center for Ecological Research, Kyoto University, Kyoto, Japan a telschow ecology kyoto u ac jp
PLoS ONE 2:e701. 2007Bacteria of the genus Wolbachia are among the most common endosymbionts in the world...
Wolbachia interferes with ferritin expression and iron metabolism in insectsNatacha Kremer
Universite de Lyon, Lyon, France
PLoS Pathog 5:e1000630. 2009b>Wolbachia is an intracellular bacterium generally described as being a facultative reproductive parasite. However, Wolbachia is necessary for oogenesis completion in the wasp Asobara tabida...
Stage-specific proteomic expression patterns of the human filarial parasite Brugia malayi and its endosymbiont WolbachiaSasisekhar Bennuru
Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA
Proc Natl Acad Sci U S A 108:9649-54. 2011..The analysis also yielded much of the proteome of Wolbachia, the obligate endosymbiont of Bm that also expressed proteins in a stage-specific manner...
Widespread recombination throughout Wolbachia genomesLaura Baldo
Department of Biology, University of California, Riverside, USA
Mol Biol Evol 23:437-49. 2006..Here we investigate the extent of recombination among housekeeping genes of the endosymbiotic bacteria Wolbachia. Four housekeeping genes, gltA, dnaA, ftsZ, and groEL, were sequenced from a sample of 22 strains belonging to ..
Computational prediction of essential genes in an unculturable endosymbiotic bacterium, Wolbachia of Brugia malayiAlexander G Holman
New England Biolabs, 240 County Road, Ipswich, MA 01938 2723, USA
BMC Microbiol 9:243. 2009b>Wolbachia (wBm) is an obligate endosymbiotic bacterium of Brugia malayi, a parasitic filarial nematode of humans and one of the causative agents of lymphatic filariasis...
Offsetting effects of Wolbachia infection and heat shock on sperm production in Drosophila simulans: analyses of fecundity, fertility and accessory gland proteinsR R Snook
Department of Organismal Biology and Anatomy, The University of Chicago, Illinois 60637, USA
Genetics 155:167-78. 2000Infection in Drosophila simulans with the endocellular symbiont Wolbachia pipientis results in egg lethality caused by failure to properly initiate diploid development (cytoplasmic incompatibility, CI)...
Wolbachia infections in Anopheles gambiae cells: transcriptomic characterization of a novel host-symbiont interactionGrant L Hughes
The W Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
PLoS Pathog 7:e1001296. 2011The endosymbiotic bacterium Wolbachia is being investigated as a potential control agent in several important vector insect species...
Generation of a novel Wolbachia infection in Aedes albopictus (Asian tiger mosquito) via embryonic microinjectionZhiyong Xi
Department of Entomology, University of Kentucky, Lexington, KY 40546, USA
Insect Biochem Mol Biol 35:903-10. 2005..Strategies of vector suppression and replacement are based upon intracellular Wolbachia bacteria, which occur naturally in many insect populations...
Infectious speciation revisited: impact of symbiont-depletion on female fitness and mating behavior of Drosophila paulistorumWolfgang J Miller
Laboratories of Genome Dynamics, Center of Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria
PLoS Pathog 6:e1001214. 2010..candidates fostering symbiont-driven speciation in arthropods are intracellular bacteria belonging to the genus Wolbachia. They are maternally inherited symbionts of many arthropods capable of manipulating host reproductive biology ..
Finding of male-killing Spiroplasma infecting Drosophila melanogaster in Africa implies transatlantic migration of this endosymbiontJ E Pool
Department of Molecular Biology and Genetics, Cornell University, 233 Biotechnology Building, Ithaca, NY 14853, USA
Heredity (Edinb) 97:27-32. 2006..melanogaster in Brazil, although part of one locus appears to show a recombinant history. Implications for the origin and history of male-killing Spiroplasma in D. melanogaster are discussed...
Heritable endosymbionts of DrosophilaMariana Mateos
Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona 85721, USA
Genetics 174:363-76. 2006..Previous efforts screened relatively few Drosophila lineages, mainly for Wolbachia. We conducted an extensive survey of potentially heritable endosymbionts from any bacterial lineage via PCR ..
Detection and characterization of Wolbachia infections in Wuchereria bancrofti (Spirurida: Onchocercidae) var. pacifica and Aedes (Stegomyia) polynesiensis (Diptera: Culicidae)Catherine Plichart
Laboratoire de Recherche en Parasitologie Médicale, Institut Louis Malarde, Papeete, Tahiti, French Polynesia
Am J Trop Med Hyg 73:354-8. 2005..For an alternative strategy to MDA, we investigated the potential role of Wolbachia to control filarial transmission...
Evidence for recombination between feminizing Wolbachia in the isopod genus ArmadillidiumSébastien Verne
Laboratoire de Génétique et Biologie des Populations de Crustacés, UMR CNRS 6556, Universite de Poitiers, 40, avenue du Recteur Pineau, Poitiers Cedex, France
Gene 397:58-66. 2007b>Wolbachia are maternally inherited endosymbiotic alpha-Proteobacteria infecting a wide range of arthropods. Wolbachia induce feminization in many terrestrial isopod species, particularly in the genus Armadillidium (Crustacea, Oniscidea)...
Wolbachia endosymbiont responsible for cytoplasmic incompatibility in a terrestrial crustacean: effects in natural and foreign hostsY Moret
, , UMR CNRS 6556, 40 Avenue du Recteur Pineau, F-86022 Poitiers Cedex, France
Heredity 86:325-32. 2001b>Wolbachia bacteria are vertically transmitted endosymbionts that disturb the reproduction of many arthropods thereby enhancing their spread in host populations...
Ultrastructural and molecular identification of a Wolbachia endosymbiont in a spider, Nephila clavataH W Oh
Insect Resources Laboratory, Korean Collection for Type Cultures, KoreaResearch Institute of Bioscience and Biotechnology, Yusong, Taejon, Korea
Insect Mol Biol 9:539-43. 2000b>Wolbachia-like bacteria were observed in the egg cells of golden orb-weaving spider, Nephila clavata, by means of transmission electron microscopy...
Distribution and evolution of bacteriophage WO in Wolbachia, the endosymbiont causing sexual alterations in arthropodsS Masui
Department of Biological Sciences, Graduate School of Science, University of Tokyo, Hongo, Bunkyo ku, Tokyo 113 0033, Japan
J Mol Evol 51:491-7. 2000b>Wolbachia are obligatory intracellular and maternally inherited bacteria, known to infect many species of arthropod...
Wolbachia transfer from Rhagoletis cerasi to Drosophila simulans: investigating the outcomes of host-symbiont coevolutionMarkus Riegler
Institute of Forest Entomology, Forest Pathology and Forest Protection, BOKU University of Natural Resources and Applied Life Sciences, 1190 Vienna, Austria
Appl Environ Microbiol 70:273-9. 2004b>Wolbachia is an endosymbiont of diverse arthropod lineages that can induce various alterations of host reproduction for its own benefice...
Wolbachia and cytoplasmic incompatibility in the California Culex pipiens mosquito species complex: parameter estimates and infection dynamics in natural populationsJason L Rasgon
Department of Entomology, University of California, Davis, California 95616, USA
Genetics 165:2029-38. 2003Before maternally inherited bacterial symbionts like Wolbachia, which cause cytoplasmic incompatibility (CI; reduced hatch rate) when infected males mate with uninfected females, can be used in a program to control vector-borne diseases ..
Sequential evolution of a symbiont inferred from the host: Wolbachia and Drosophila simulansJ William O Ballard
The Roy J. Carver Center for Comparative Genomics, Department of Biological Science, University of Iowa, USA
Mol Biol Evol 21:428-42. 2004..64 sampling localities was employed to infer the phylogeography of the maternally inherited alpha-proteobacteria Wolbachia. Phylogenetic analyses, from three symbiont genes and 24 mtDNA genomes (excluding the A + T-rich region), showed ..
Wolbachia-induced cytoplasmic incompatibility in Japanese populations of Tetranychus urticae (Acari: Tetranychidae)Tetsuo Gotoh
Faculty of Agriculture, Ibaraki University, Ami, Ibaraki, 300 0393, Japan
Exp Appl Acarol 42:1-16. 2007Intracellular bacteria of the genus Wolbachia (alpha Proteobacteria) induce cytoplasmic incompatibility (CI) in many arthropod species, including spider mites, but not all Wolbachia cause CI...
Wolbachia infection in the newly described Ecuadorian sand flea, Tunga trimamillataAndrea Luchetti
Dipartimento di Biologia Evoluzionistica Sperimentale, Universita di Bologna, Bologna, Italy
Exp Parasitol 108:18-23. 2004b>Wolbachia pipientis is an intracellular endosymbiont producing reproductive alterations in its hosts. This bacterium have been reported in many arthropods and nematodes...
Wolbachia pipientis in Australian spidersSimone M Rowley
Department of Zoology and Entomology, School of Life Sciences, University of Queensland, St. Lucia, QLD 4072, Australia
Curr Microbiol 49:208-14. 2004b>Wolbachia pipientis is an endosymbiotic bacterium common to arthropods and filarial nematodes. This study presents the first survey and characterization of Wolbachia pipientis that infect spiders...
Competing selfish genetic elements in the butterfly Hypolimnas bolinaSylvain Charlat
Department of Biology, University College London, 4 Stephenson Way, London NW1 2HE, United Kingdom
Curr Biol 16:2453-8. 2006..In this paper, we show that spatial heterogeneity in the occurrence of the male-killing Wolbachia wBol1 in the tropical butterfly Hypolimnas bolina is caused by a second infection that can exclude the male-..
Wolbachia genome integrated in an insect chromosome: evolution and fate of laterally transferred endosymbiont genesNaruo Nikoh
Division of Natural Sciences, The University of the Air, Chiba 261 8586, Japan
Genome Res 18:272-80. 2008..Here we thoroughly investigated the bacterial genes derived from a Wolbachia endosymbiont on the nuclear genome of the beetle Callosobruchus chinensis...
The bacterial catalase from filarial DNA preparations derives from common pseudomonad contaminants and not from Wolbachia endosymbiontsJeremy Foster
New England Biolabs, Beverly, MA 01915, USA
Parasitol Res 94:141-6. 2004b>Wolbachia are obligatory endosymbionts in many species of filarial nematodes...
Disruption of the Wolbachia surface protein gene wspB by a transposable element in mosquitoes of the Culex pipiens complex (Diptera, Culicidae)Y O Sanogo
Illinois Natural History Survey, Champaign, IL 61820, USA
Insect Mol Biol 16:143-54. 2007..Both Cx. p. quinquefasciatus and Cx. p. pipiens are infected with the endosymbiotic bacteria Wolbachia pipientis...
Multiple infection with Wolbachia inducing different reproductive manipulations in the butterfly Eurema hecabeMasato Hiroki
Department of Biology, International Christian University, Miataka, Tokyo 181 8585, Japan
Proc Biol Sci 271:1751-5. 2004b>Wolbachia are rickettsial intracellular symbionts of arthropods and nematodes. In arthropods, they act as selfish genetic elements and manipulate host reproduction, including sex-ratio distortion and cytoplasmic incompatibility (CI)...
Population dynamics of Wolbachia bacterial endosymbionts in Brugia malayiHelen F McGarry
Filariasis Research Laboratory, Molecular and Biochemical Parasitology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK
Mol Biochem Parasitol 135:57-67. 2004The human filarial nematode Brugia malayi contains an endosymbiotic bacterium, Wolbachia. We used real-time quantitative polymerase chain reaction (QPCR) and microscopy to investigate the population dynamics of the bacterium-nematode ..
Molecular discrimination of Wolbachia in the Culex pipiens complex: evidence for variable bacteriophage hyperparasitismY O Sanogo
Department of Entomology, University of Kentucky, Lexington, KY, USA
Insect Mol Biol 13:365-9. 2004..Cytoplasmic incompatibility (CI) caused by endosymbiotic Wolbachia bacteria is thought to play an important role in restricting gene flow and the evolution of the Culex complex...
Phylogenetic relationships of the Wolbachia of nematodes and arthropodsKatelyn Fenn
Institutes of Evolutionary Biology and Immunology and Infection Research, University of Edinburgh, Edinburgh, United Kingdom
PLoS Pathog 2:e94. 2006b>Wolbachia are well known as bacterial symbionts of arthropods, where they are reproductive parasites, but have also been described from nematode hosts, where the symbiotic interaction has features of mutualism...
Wolbachia transmission dynamics in Formica wood antsLumi Viljakainen
Department of Biology, PO Box 3000, 90014 University of Oulu, Finland
BMC Evol Biol 8:55. 2008The role of Wolbachia endosymbionts in shaping the mitochondrial diversity of their arthropod host depends on the effects they have on host reproduction and on the mode of transmission of the bacteria...
Multilocus sequence typing system for the endosymbiont Wolbachia pipientisLaura Baldo
Department of Biology, University of California, 900 University Avenue, Riverside, CA 92521, USA
Appl Environ Microbiol 72:7098-110. 2006The eubacterial genus Wolbachia comprises one of the most abundant groups of obligate intracellular bacteria, and it has a host range that spans the phyla Arthropoda and Nematoda...
Distribution of the bacterial symbiont Cardinium in arthropodsEinat Zchori-Fein
Department of Vegetable Crops, Agricultural Research Organization, Newe Ya ar Research Center, Ramat Yishay, 30095, Israel
Mol Ecol 13:2009-16. 2004..These arthropods were also screened for the presence of the better-known reproductive manipulator, Wolbachia. Six per cent of the species screened tested positive for Cardinium, compared with 24% positive for Wolbachia...
Strain-specific quantification of Wolbachia density in Aedes albopictus and effects of larval rearing conditionsT J Dutton
Vector Research Group, Liverpool School of Tropical Medicine, Liverpool, UK
Insect Mol Biol 13:317-22. 2004The density of the endosymbiont Wolbachia can influence the expression of the crossing sterilities known as cytoplasmic incompatibility (CI), and also its rate of maternal transmission...
Fitness advantage and cytoplasmic incompatibility in Wolbachia single- and superinfected Aedes albopictusS L Dobson
Department of Entomology, University of Kentucky, Lexington, KY 40546, USA
Heredity (Edinb) 93:135-42. 2004b>Wolbachia are obligate, maternally inherited, intracellular bacteria that infect numerous insects and other invertebrates...
Canine onchocercosis in Greece: report of further 20 cases and molecular characterization of the parasite and its Wolbachia endosymbiontA Komnenou
Clinic of Surgery, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, St. Voutyra 11 Street, 546-27 Thessaloniki, Greece
Vet Parasitol 118:151-5. 2003..removed from Greek dogs and its Wolbachia endosymbionts...
Incidence of the endosymbionts Wolbachia, Cardinium and Spiroplasma in phytoseiid mites and associated preyMonika Enigl
Institute of Plant Protection, Department of Applied Plant Sciences and Plant Biotechnology, University of Natural Resources and Applied Life Sciences, Peter Jordanstrasse 82, 1190 Vienna, Austria
Exp Appl Acarol 42:75-85. 2007..We screened 20 strains of 12 agriculturally relevant herbivorous and predatory mite species for infection with Wolbachia, Cardinium and Spiroplasma by the use of PCR...
High levels of multiple Wolbachia infection and recombination in the ant Formica exsectaMax Reuter
Institute of Ecology, University of Lausanne, Batiment de Biologie, Lausanne, Switzerland
Mol Biol Evol 20:748-53. 2003b>Wolbachia bacteria are intracellular symbionts of many arthropod species. Their spread through host populations is promoted by drastic alterations imposed on their hosts' reproductive physiology...
Genetic conflicts over sex ratio: mite-endosymbiont interactionsFilipa Vala
Institute for Biodiversity and Ecosystem Dynamics, Section of Population Biology, University of Amsterdam, P O Box 94084, Amsterdam 1090 GB, The Netherlands
Am Nat 161:254-66. 2003..Here we investigate the conflict over sex ratio between the cytoplasmic bacterium Wolbachia and the two-spotted spider mite Tetranychus urticae Koch...
Intra-individual coexistence of a Wolbachia strain required for host oogenesis with two strains inducing cytoplasmic incompatibility in the wasp Asobara tabidaFranck Dedeine
Biometrie et Biologie Evolutive, Universite Claude Bernard Lyon 1, 69 622 Villeurbanne Cedex, France
Evolution 58:2167-74. 2004Cytoplasmically inherited symbiotic Wolbachia bacteria are known to induce a diversity of phenotypes on their numerous arthropod hosts including cytoplasmic incompatibility, male-killing, thelytokous parthenogenesis, and feminization...
Molecular phylogeny of Wolbachia endosymbionts in Southeast Asian mosquitoes (Diptera: Culicidae) based on wsp gene sequencesToon Ruang-areerate
Center for Vectors and Vector Borne Diseases, Faculty of Science, Mahidol University, Rama 6 Road, Bangkok 10400, Thailand
J Med Entomol 40:1-5. 2003b>Wolbachia are maternally inherited intracellular bacteria that infect a wide range of arthropods and nematodes and are associated with various reproductive abnormalities in their hosts...
Evolutionary dynamics of a spatially structured host-parasite association: Drosophila innubila and male-killing WolbachiaKelly A Dyer
Department of Biology, University of Rochester, Rochester, New York 14627, USA
Evolution 59:1518-28. 2005..and epidemiologically characterize populations of the mycophagous fly Drosophila innubila and its male-killing Wolbachia endosymbiont, with the aim of integrating the local through global nature of this association...
New names for old strains? Wolbachia wSim is actually wRiInaki Iturbe-Ormaetxe
Genome Biol 6:401; author reply 401. 2005
Wolbachia and nuclear-nuclear interactions contribute to reproductive incompatibility in the spider mite Panonychus mori (Acari: Tetranychidae)T Gotoh
Faculty of Agriculture, Ibaraki University, Ami, Ibaraki 300 0393, Japan
Heredity (Edinb) 94:237-46. 2005Maternally transmitted bacteria of the genus Wolbachia are obligate, intracellular symbionts that are responsible for cytoplasmic incompatibility in a wide range of arthropods such as insects and mites...
Expression and modulation of embryonic male-killing in Drosophila innubila: opportunities for multilevel selectionKelly A Dyer
Department of Biology, University of Rochester, Rochester, New York 14627, USA
Evolution 59:838-48. 2005..This study uses a male-killing Wolbachia endosymbiont and its host Drosophila innubila to experimentally address the potential for multilevel selection ..
Electron microscopic and molecular identification of Wolbachia endosymbionts from Onchocerca lupi: implications for therapyZ Egyed
Department of Immunology and Molecular Biology, Department of Wildlife Diseases and Parasitology, Central Veterinary Institute, Budapest, Hungary
Vet Parasitol 106:75-82. 2002It was recently demonstrated that Wolbachia intracellular bacteria (alpha 2 proteobacteria, Rickettsiales) living in filarial nematodes are obligatory symbionts of their hosts...
The Allonemobius-Wolbachia host-endosymbiont system: evidence for rapid speciation and against reproductive isolation driven by cytoplasmic incompatibilityJeremy L Marshall
Department of Biology, The University of Texas at Arlington, Box 19498, 501 South Nedderman Drive, Arlington, Texas 76019 0498, USA
Evolution 58:2409-25. 2004..and rapid speciation can be biased by the occurrence of hybridization and reproductive endosymbionts such as Wolbachia. For example, patterns of mitochondrial DNA (mtDNA) variation can be obscured by mitotypes hitchhiking on ..
Molecular phylogenetic analysis of Onchocerca lupi and its Wolbachia endosymbiontZ Egyed
Department of Immunology and Molecular Biology, Central Veterinary Institute, Budapest, Hungary
Vet Parasitol 108:153-61. 2002..the 5S ribosomal RNA gene spacer region sequence of the parasite and the 16S ribosomal RNA gene sequence of its Wolbachia endosymbiotic bacteria (Rickettsiales) supported the morphological and biological arguments that O...
Research Grants
- Development of a novel nematode/Wolbachia targetClotilde Carlow; Fiscal Year: 2007..Active compounds may also be tested for their effects on other organisms that possess the target. This will provide the basis for discovering a new class of drugs that may be used in veterinary and human medicine. ..
- The Role of Wolbachia Endobacteria in River BlindnessEric Pearlman; Fiscal Year: 2007..Rickettsia - like Wolbachia bacteria are essential symbionts of the major pathogenic filarial nematode parasites of humans, including the ..
- The Role of Wolbachia Endobacteria in River BlindnessEric Pearlman; Fiscal Year: 2007..Rickettsia - like Wolbachia bacteria are essential symbionts of the major pathogenic filarial nematode parasites of humans, including the ..
- Proximal determinants of risk for tularemia outbreaksSam Telford; Fiscal Year: 2004..previously classified as Wolbachia sp.) common within tissues of dog ticks, Dermacentor variabilis...
- The molecular basis of bacteria-host interaction Drosophila melanogasterLAURA SERBUS; Fiscal Year: 2007One of the most successful intracellular bacteria is Wolbachia, harbored by thousands of arthropods and nematodes. Wolbachia have recently been shown cause blindness in humans upon release from their nematode host Onchocerca volvulus...
- Macrofilaricidal Aminoacyl-tRNA Synthetase InhibitorsMichael Kron; Fiscal Year: 2005..by this new research program include both the unique AARS expressed in filarial parasites and those within the Wolbachia endosymbiotic bacteria that are essential for worm viability...
- Mapping Protein Interactions between Filaria and its Wolbachia EndosymbiontThomas R Unnasch; Fiscal Year: 2010..Most of the human filarial parasite species harbor an endosymbiotic bacterium of the genus Wolbachia. These endo-bacteria are essential, as elimination of the endosymbiont leads to sterilization of the adult ..
- Population genetics of transgenes in mosquito vectorsFred Gould; Fiscal Year: 2007..3) engineered underdominance, 4) insertion of loaded autonomous transposons, 5) infection with transgenic Wolbachia strains. The potential for using novel transgenic manipulations will be examined with more general models...
- Evolutionary genetics of tsetse and its symbiontsSerap Aksoy; Fiscal Year: 2010..into natural tsetse populations by cytoplasmic incompatibility phenomenon mediated by tsetse's symbiont, Wolbachia. We propose to investigate the biogeography of the human disease vector species, Glossina fuscipes fuscipes, its ..
- Evolutionary genetics of tsetse and its symbiontsSerap Aksoy; Fiscal Year: 2010..into natural tsetse populations by cytoplasmic incompatibility phenomenon mediated by tsetse's symbiont, Wolbachia. We propose to investigate the biogeography of the human disease vector species, Glossina fuscipes fuscipes, its ..
- Evolutionary genetics of tsetse and its symbiontsSerap Aksoy; Fiscal Year: 2009..into natural tsetse populations by cytoplasmic incompatibility phenomenon mediated by tsetse's symbiont, Wolbachia. We propose to investigate the biogeography of the human disease vector species, Glossina fuscipes fuscipes, its ..
- REGULATION OF SEX SPECIFIC GENES IN DROSOPHILAThomas Cline; Fiscal Year: 2006..is sought of how and why Sxl functions in germ cells and how the obligate intracellular parasitic bacterium Wolbachia pipientis interacts with it in that cell type...
- Eradication of a Primary Filariasis Vector Population at an Endemic Field SiteSTEPHEN LEONARD DOBSON; Fiscal Year: 2010..Here, we propose a novel strategy in which releases of male Ae. polynesiensis mosquitoes infected with Wolbachia bacteria result in the sterilization of female mosquitoes at a field site endemic for filariasis transmission...
- Vector Population Modification Using Wolbachia SymbiontsStephen Dobson; Fiscal Year: 2006DESCRIPTION (provided by the applicant): Intracellular Wolbachia bacteria infect a diverse range of invertebrate hosts, including medically important disease vectors...
- Eradication of a Primary Filariasis Vector Population at an Endemic Field SiteStephen Dobson; Fiscal Year: 2007..Here, we propose a novel strategy in which releases of male Ae. polynesiensis mosquitoes infected with Wolbachia bacteria result in the sterilization of female mosquitoes at a field site endemic for filariasis transmission...
- Vector Population Modification Using Wolbachia SymbiontsStephen Dobson; Fiscal Year: 2003DESCRIPTION (provided by the applicant): Intracellular Wolbachia bacteria infect a diverse range of invertebrate hosts, including medically important disease vectors...
- Genetic basis of WNV vector competence in Culex tarsalisJason Rasgon; Fiscal Year: 2007..This work also has important relevance for bioterrorism issues because it will provide insight into how intrinsic vector genetic factors in mosquito populations affect the epidemiology of a released Category B agent. ..
- Genetic basis of WNV vector competence in Culex tarsalisJason L Rasgon; Fiscal Year: 2010..This work also has important relevance for bioterrorism issues because it will provide insight into how intrinsic vector genetic factors in mosquito populations affect the epidemiology of a released Category B agent. ..
- Wolbachia as an Agent for Population Replacement in Anopheles GambiaeJason Rasgon; Fiscal Year: 2007..b>Wolbachia are maternally inherited endosymbionts associated with cytoplasmic incompatibility (CI) i.e...
- SYNTHESIS AND DEGRADATION OF RIBOSOMES IN THE MOSQUITOAnn Fallon; Fiscal Year: 1993..These studies will contribute to an increased understanding of the genetics and physiology of the mosquito, a disease vector with considerable impact on human health and productivity...
- SYNTHESIS AND DEGRADATION OF RIBOSOMES IN THE MOSQUITOAnn Fallon; Fiscal Year: 1999..These studies will contribute new information and analytical approaches to investigate gene expression and provide molecular infrastructure essential to disruption of disease transmission in genetically transformed mosquitoes. ..
- MOSQUITO IMMUNITY FUNCTIONSAnn Fallon; Fiscal Year: 2003..The work will include identification of exon-intron organization and recovery of upstream flanking DNA, which will be analyzed for potential regulatory elements. ..
- In vitro culture and transformation of Wolbachia from mosquitoesAnn Fallon; Fiscal Year: 2007..The intracellular bacterium, Wolbachia pipientis, provides an attractive drive mechanism, because it favors its own transmission through a reproductive ..
- SYNTHESIS AND DEGRADATION OF RIBOSOMES IN THE MOSQUITOAnn Fallon; Fiscal Year: 2004..These studies provide cloned genes, molecular approaches, and characterization of regulatory processes that can potentially be manipulated to interfere with disease transmission by blood-feeding arthropods. ..
- FACTORS AFFECTING GROWTH OF BRUGIA MALAYI IN SCID MICETHIRUCHANDURAI RAJAN; Fiscal Year: 2006..More excitingly, they might help us identify the epitope that forms the target of host defense raising the possibility, long-term, of generating an immuno-prophylactic strategy against filarial infections. ..
- FACTORS AFFECTING GROWTH OF BRUGIA MALAYI IN SCID MICETHIRUCHANDURAI RAJAN; Fiscal Year: 2000..b) the influence of alleles at the Nramp and iNOS loci on murine susceptibility to B. malayi. (c). the role of cytokines controlling the induction of nitric oxide in the resistance of NOD/LtSz-scid mice to B. malayi. ..
