wolbachia

Summary

Summary: A genus of bacteria comprised of a heterogenous group of gram-negative small rods and coccoid forms associated with arthropods. (From Bergey's Manual of Systematic Bacteriology, vol 1, 1984)

Top Publications

  1. ncbi A Wolbachia symbiont in Aedes aegypti limits infection with dengue, Chikungunya, and Plasmodium
    Luciano A Moreira
    School of Biological Sciences, The University of Queensland, Brisbane QLD 4072, Australia
    Cell 139:1268-78. 2009
  2. ncbi How many species are infected with Wolbachia?--A statistical analysis of current data
    Kirsten Hilgenboecker
    Institute for Theoretical Biology, Humboldt University Berlin, Berlin, Germany
    FEMS Microbiol Lett 281:215-20. 2008
  3. ncbi Immune activation by life-shortening Wolbachia and reduced filarial competence in mosquitoes
    Zakaria Kambris
    Peter Medawar Building for Pathogen Research and Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Science 326:134-6. 2009
  4. ncbi Wolbachia stimulates immune gene expression and inhibits plasmodium development in Anopheles gambiae
    Zakaria Kambris
    Department of Zoology, University of Oxford, Peter Medawar Building for Pathogen Research, Oxford, United Kingdom
    PLoS Pathog 6:e1001143. 2010
  5. ncbi Wolbachia: master manipulators of invertebrate biology
    John H Werren
    Biology Department, University of Rochester, Rochester, New York, New York 14627, USA
    Nat Rev Microbiol 6:741-51. 2008
  6. ncbi The endosymbiotic bacterium Wolbachia induces resistance to dengue virus in Aedes aegypti
    Guowu Bian
    Department of Entomology and Genetics Program, Michigan State University, East Lansing, Michigan, United States of America
    PLoS Pathog 6:e1000833. 2010
  7. ncbi Complete WO phage sequences reveal their dynamic evolutionary trajectories and putative functional elements required for integration into the Wolbachia genome
    Kohjiro Tanaka
    National Institute of Advanced Industrial Science and Technology AIST, 1 1 1 Higashi, Tsukuba 305 8566, Japan
    Appl Environ Microbiol 75:5676-86. 2009
  8. ncbi Wolbachia: more than just a bug in insects genitals
    Aggeliki Saridaki
    Department of Environmental and Natural Resources Management, University of Ioannina, Agrinio, Greece
    Curr Opin Microbiol 13:67-72. 2010
  9. ncbi The native Wolbachia endosymbionts of Drosophila melanogaster and Culex quinquefasciatus increase host resistance to West Nile virus infection
    Robert L Glaser
    Wadsworth Center, New York State Department of Health, Albany, New York, United States of America
    PLoS ONE 5:e11977. 2010
  10. ncbi Complete bacteriophage transfer in a bacterial endosymbiont (Wolbachia) determined by targeted genome capture
    Bethany N Kent
    Department of Biological Sciences, Vanderbilt University, USA
    Genome Biol Evol 3:209-18. 2011

Detail Information

Publications275 found, 100 shown here

  1. ncbi A Wolbachia symbiont in Aedes aegypti limits infection with dengue, Chikungunya, and Plasmodium
    Luciano A Moreira
    School of Biological Sciences, The University of Queensland, Brisbane QLD 4072, Australia
    Cell 139:1268-78. 2009
    b>Wolbachia are maternally inherited intracellular bacterial symbionts that are estimated to infect more than 60% of all insect species...
  2. ncbi How many species are infected with Wolbachia?--A statistical analysis of current data
    Kirsten Hilgenboecker
    Institute for Theoretical Biology, Humboldt University Berlin, Berlin, Germany
    FEMS Microbiol Lett 281:215-20. 2008
    b>Wolbachia are intracellular bacteria found in many species of arthropods and nematodes...
  3. ncbi Immune activation by life-shortening Wolbachia and reduced filarial competence in mosquitoes
    Zakaria Kambris
    Peter Medawar Building for Pathogen Research and Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Science 326:134-6. 2009
    b>Wolbachia strain wMelPop reduces the longevity of its Drosophila melanogaster host and, when introduced into the mosquito Aedes aegypti, halves its life span...
  4. ncbi Wolbachia stimulates immune gene expression and inhibits plasmodium development in Anopheles gambiae
    Zakaria Kambris
    Department of Zoology, University of Oxford, Peter Medawar Building for Pathogen Research, Oxford, United Kingdom
    PLoS Pathog 6:e1001143. 2010
    The over-replicating wMelPop strain of the endosymbiont Wolbachia pipientis has recently been shown to be capable of inducing immune upregulation and inhibition of pathogen transmission in Aedes aegypti mosquitoes...
  5. ncbi Wolbachia: master manipulators of invertebrate biology
    John H Werren
    Biology Department, University of Rochester, Rochester, New York, New York 14627, USA
    Nat Rev Microbiol 6:741-51. 2008
    b>Wolbachia are common intracellular bacteria that are found in arthropods and nematodes...
  6. ncbi The endosymbiotic bacterium Wolbachia induces resistance to dengue virus in Aedes aegypti
    Guowu Bian
    Department of Entomology and Genetics Program, Michigan State University, East Lansing, Michigan, United States of America
    PLoS Pathog 6:e1000833. 2010
    ..The endosymbiotic bacterium Wolbachia has long been promoted as a potential vehicle for introducing disease-resistance genes into mosquitoes, thereby ..
  7. ncbi Complete WO phage sequences reveal their dynamic evolutionary trajectories and putative functional elements required for integration into the Wolbachia genome
    Kohjiro Tanaka
    National Institute of Advanced Industrial Science and Technology AIST, 1 1 1 Higashi, Tsukuba 305 8566, Japan
    Appl Environ Microbiol 75:5676-86. 2009
    b>Wolbachia endosymbionts are ubiquitously found in diverse insects including many medical and hygienic pests, causing a variety of reproductive phenotypes, such as cytoplasmic incompatibility, and thereby efficiently spreading in host ..
  8. ncbi Wolbachia: more than just a bug in insects genitals
    Aggeliki Saridaki
    Department of Environmental and Natural Resources Management, University of Ioannina, Agrinio, Greece
    Curr Opin Microbiol 13:67-72. 2010
    Research on the intracellular bacterial symbiont Wolbachia has grown on many levels, providing interesting insights on various aspects of the microbe's biology...
  9. ncbi The native Wolbachia endosymbionts of Drosophila melanogaster and Culex quinquefasciatus increase host resistance to West Nile virus infection
    Robert L Glaser
    Wadsworth Center, New York State Department of Health, Albany, New York, United States of America
    PLoS ONE 5:e11977. 2010
    The bacterial endosymbiont Wolbachia pipientis has been shown to increase host resistance to viral infection in native Drosophila hosts and in the normally Wolbachia-free heterologous host Aedes aegypti when infected by Wolbachia from ..
  10. ncbi Complete bacteriophage transfer in a bacterial endosymbiont (Wolbachia) determined by targeted genome capture
    Bethany N Kent
    Department of Biological Sciences, Vanderbilt University, USA
    Genome Biol Evol 3:209-18. 2011
    ..as single genes or larger regions between coinfections, we sequenced the genome of the obligate intracellular Wolbachia strain wVitB from the parasitic wasp Nasonia vitripennis and compared it against the prophage sequences of the ..
  11. ncbi The mosaic genome structure of the Wolbachia wRi strain infecting Drosophila simulans
    Lisa Klasson
    Department of Molecular Evolution, Evolutionary Biology Centre, Uppsala University, SE 752 36 Uppsala, Sweden
    Proc Natl Acad Sci U S A 106:5725-30. 2009
    The obligate intracellular bacterium Wolbachia pipientis infects around 20% of all insect species...
  12. ncbi Extensive genomic diversity of closely related Wolbachia strains
    Nadeeza Ishmael
    J Craig Venter Institute, 9708 Medical Center Dr, Rockville, MD 20850, USA
    Microbiology 155:2211-22. 2009
    Using microarray-based comparative genome hybridization (mCGH), the genomic content of Wolbachia pipientis wMel from Drosophila melanogaster was compared to the closely related Wolbachia from D. innubila (wInn), D...
  13. ncbi Phage WO of Wolbachia: lambda of the endosymbiont world
    Bethany N Kent
    Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA
    Trends Microbiol 18:173-81. 2010
    The discovery of an extraordinarily high level of mobile elements in the genome of Wolbachia, a widespread arthropod and nematode endosymbiont, suggests that this bacterium could be an excellent model for assessing the evolution and ..
  14. ncbi Genome evolution of Wolbachia strain wPip from the Culex pipiens group
    Lisa Klasson
    Peter Medawar Building for Pathogen Research and Department of Zoology, University of Oxford, Oxford, United Kingdom
    Mol Biol Evol 25:1877-87. 2008
    The obligate intracellular bacterium Wolbachia pipientis strain wPip induces cytoplasmic incompatibility (CI), patterns of crossing sterility, in the Culex pipiens group of mosquitoes. The complete sequence is presented of the 1...
  15. ncbi Variation in antiviral protection mediated by different Wolbachia strains in Drosophila simulans
    Sheree E Osborne
    School of Biological Sciences, The University of Queensland, St Lucia, Queensland, Australia
    PLoS Pathog 5:e1000656. 2009
    ..The Drosophila host is also commonly infected with the widespread endosymbiotic bacteria Wolbachia pipientis. When DCV coinfects Wolbachia-infected D...
  16. ncbi Isolation and characterization of the bacteriophage WO from Wolbachia, an arthropod endosymbiont
    Yukiko Fujii
    Department of Biological Sciences, Graduate School of Science, University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
    Biochem Biophys Res Commun 317:1183-8. 2004
    b>Wolbachia is a group of obligate symbiotic bacteria found in many insects and other arthropods. The presence of Wolbachia alters reproduction in the host, but the mechanisms are unknown...
  17. ncbi Wolbachia-mediated cytoplasmic incompatibility is associated with impaired histone deposition in the male pronucleus
    Frédéric Landmann
    Department of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, USA
    PLoS Pathog 5:e1000343. 2009
    b>Wolbachia is a bacteria endosymbiont that rapidly infects insect populations through a mechanism known as cytoplasmic incompatibility (CI)...
  18. ncbi Asymmetric Wolbachia segregation during early Brugia malayi embryogenesis determines its distribution in adult host tissues
    Frédéric Landmann
    Department of Molecular, Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America
    PLoS Negl Trop Dis 4:e758. 2010
    b>Wolbachia are required for filarial nematode survival and fertility and contribute to the immune responses associated with human filarial diseases...
  19. ncbi Stable introduction of a life-shortening Wolbachia infection into the mosquito Aedes aegypti
    Conor J McMeniman
    School of Integrative Biology, University of Queensland, Brisbane 4072, Australia
    Science 323:141-4. 2009
    ..The successful transfer of a life-shortening strain of the inherited bacterial symbiont, Wolbachia, into the major mosquito vector of dengue, Aedes aegypti, halved adult life span under laboratory conditions...
  20. ncbi Wolbachia and virus protection in insects
    Lauren M Hedges
    School of Integrative Biology, University of Queensland, Brisbane 4072, Australia
    Science 322:702. 2008
    b>Wolbachia pipientis bacteria are common endosymbionts of insects that are best known for their ability to increase their prevalence in populations by manipulating host reproductive systems...
  21. ncbi The tripartite associations between bacteriophage, Wolbachia, and arthropods
    Seth R Bordenstein
    Josephine Bay Paul Center for Comparative Molecular Biology and Evolution, The Marine Biological Laboratory, Woods Hole, Massachusetts, USA
    PLoS Pathog 2:e43. 2006
    By manipulating arthropod reproduction worldwide, the heritable endosymbiont Wolbachia has spread to pandemic levels...
  22. ncbi Wolbachia distribution and cytoplasmic incompatibility during sperm development: the cyst as the basic cellular unit of CI expression
    Michael E Clark
    Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL 60637, USA
    Mech Dev 120:185-98. 2003
    The growth and distribution of the intracellular microbe Wolbachia pipientis during spermatogenesis in several different host/symbiont genetic combinations in Drosophila melanogaster and Drosophila simulans is described...
  23. ncbi The genetics and cell biology of Wolbachia-host interactions
    Laura R Serbus
    Molecular, Cell and Developmental Biology, University of California, Santa Cruz, California 95064, USA
    Annu Rev Genet 42:683-707. 2008
    b>Wolbachia are gram-negative bacteria that are widespread in nature, carried by the majority of insect species as well as some mites, crustaceans, and filarial nematodes...
  24. ncbi Bacteriophage flux in endosymbionts (Wolbachia): infection frequency, lateral transfer, and recombination rates
    Seth R Bordenstein
    The Marine Biological Laboratory, Josephine Bay Paul Center for Comparative Molecular Biology and Evolution, Woods Hole, Massachusetts, USA
    Mol Biol Evol 21:1981-91. 2004
    ..been influential in the genome evolution of the most prevalent bacterial endosymbiont of invertebrates, Wolbachia. First, we show that bacteriophage WO is more widespread in Wolbachia than previously recognized, occurring in ..
  25. ncbi Increased locomotor activity and metabolism of Aedes aegypti infected with a life-shortening strain of Wolbachia pipientis
    Oliver Evans
    School of Biological Sciences, The University of Queensland, St Lucia, Queensland, 4072, Australia
    J Exp Biol 212:1436-41. 2009
    A virulent strain of the obligate intracellular bacterium Wolbachia pipientis that shortens insect lifespan has recently been transinfected into the primary mosquito vector of dengue virus, Aedes aegypti L...
  26. ncbi The bacterial symbiont Wolbachia induces resistance to RNA viral infections in Drosophila melanogaster
    Luis Teixeira
    Department of Genetics, University of Cambridge, Cambridge, United Kingdom
    PLoS Biol 6:e2. 2008
    b>Wolbachia are vertically transmitted, obligatory intracellular bacteria that infect a great number of species of arthropods and nematodes...
  27. ncbi An endosymbiotic bacterium in a plant-parasitic nematode: member of a new Wolbachia supergroup
    Annelies Haegeman
    Department of Molecular Biotechnology, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium
    Int J Parasitol 39:1045-54. 2009
    b>Wolbachia is an endosymbiotic bacterium widely present in arthropods and animal-parasitic nematodes. Despite previous efforts, it has never been identified in plant-parasitic nematodes...
  28. ncbi Remarkable abundance and evolution of mobile group II introns in Wolbachia bacterial endosymbionts
    Sébastien Leclercq
    Centre National de la Recherche Scientifique UMR 6556 Ecologie, Evolution, Symbiose, Universite de Poitiers, Poitiers, France
    Mol Biol Evol 28:685-97. 2011
    ..Yet, the genomes of Wolbachia, one of the most abundant bacterial endosymbionts on Earth, are littered with transposable elements, in ..
  29. ncbi Widespread lateral gene transfer from intracellular bacteria to multicellular eukaryotes
    Julie C Dunning Hotopp
    Institute for Genomic Research, J Craig Venter Institute, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Science 317:1753-6. 2007
    ..However, the presence of endosymbionts, such as Wolbachia pipientis, within some eukaryotic germlines may facilitate bacterial gene transfers to eukaryotic host genomes...
  30. ncbi Strain-specific regulation of intracellular Wolbachia density in multiply infected insects
    L Mouton
    Laboratoire de Biometrie et Biologie Evolutive, Universite Claude Bernard, 43 Boulevard du 11 Novembre 1918, 69622 Villeurbanne Cedex, France
    Mol Ecol 12:3459-65. 2003
    ..b>Wolbachia endosymbionts that induce cytoplasmic incompatibility in their hosts depart from this rule, because cytoplasmic ..
  31. ncbi Diversity, distribution and specificity of WO phage infection in Wolbachia of four insect species
    L Gavotte
    Laboratoire de Biometrie et Biologie Evolutive, Université Lyon I CNRS, Villeurbanne, France
    Insect Mol Biol 13:147-53. 2004
    The bacteriophage WO was recently characterized in Wolbachia, a strictly intracellular bacterium that causes several reproductive alterations in its arthropod hosts...
  32. ncbi Functional conservation of the lipid II biosynthesis pathway in the cell wall-less bacteria Chlamydia and Wolbachia: why is lipid II needed?
    Beate Henrichfreise
    Institute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany
    Mol Microbiol 73:913-23. 2009
    ..Genes for enzymes of both machineries have been found in the genomes of the cell wall-less genera Chlamydia and Wolbachia, raising questions as to the functionality of the lipid II biosynthesis pathway and reasons for its conservation...
  33. ncbi Wolbachia infection frequencies in insects: evidence of a global equilibrium?
    J H Werren
    Department of Biology, University of Rochester, NY 14627, USA
    Proc Biol Sci 267:1277-85. 2000
    b>Wolbachia are a group of cytoplasmically inherited bacteria that cause reproduction alterations in arthropods, including parthenogenesis, reproductive incompatibility, feminization of genetic males and male killing...
  34. ncbi Wolbachia pipientis: an expanding bag of tricks to explore for disease control
    Peter E Cook
    School of Biological Sciences, The University of Queensland, Brisbane, Australia
    Trends Parasitol 26:373-5. 2010
    b>Wolbachia pipientis are maternally inherited, endosymbiotic bacteria that are widespread among insects...
  35. ncbi Symbiont genes in host genomes: fragments with a future?
    Mark Blaxter
    Institute of Evolutionary Biology, School of Biological Sciences, Ashworth Laboratories, King s Buildings, University of Edinburgh, West Mains Road, Edinburgh, Scotland EH9 3JT, UK
    Cell Host Microbe 2:211-3. 2007
    ..Germline-transmitted animal symbionts, such as Wolbachia pipientis, are well placed to participate in such transfers. In a recent issue of Science, Dunning Hotopp et al...
  36. ncbi Wolbachia as a bacteriocyte-associated nutritional mutualist
    Takahiro Hosokawa
    National Institute of Advanced Industrial Science and Technology, Tsukuba 305 8566, Japan
    Proc Natl Acad Sci U S A 107:769-74. 2010
    ..Facultative and parasitic bacterial symbionts like Wolbachia have been regarded as evolutionarily distinct from such obligate nutritional mutualists...
  37. ncbi Wolbachia-induced cytoplasmic incompatibility as a means for insect pest population control
    Sofia Zabalou
    Department of Medical Sciences, Medical School, University of Crete, Heraklion 711 10, Crete, Greece
    Proc Natl Acad Sci U S A 101:15042-5. 2004
    ..b>Wolbachia are inherited bacteria of arthropods that have recently attracted attention for their potential as new ..
  38. ncbi Human probing behavior of Aedes aegypti when infected with a life-shortening strain of Wolbachia
    Luciano A Moreira
    School of Biological Sciences, The University of Queensland, St Lucia, Queensland, Australia
    PLoS Negl Trop Dis 3:e568. 2009
    ..Alternative strategies include the proposed use of inherited life-shortening agents, such as the Wolbachia bacterium...
  39. ncbi The genome of Brugia malayi - all worms are not created equal
    Alan L Scott
    Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Parasitol Int 58:6-11. 2009
    ..genetic basis for mutualism, as Brugia, like a majority of filarial species, harbors an endosybiotic bacterium (Wolbachia)...
  40. ncbi Multiple rescue factors within a Wolbachia strain
    Sofia Zabalou
    Institute of Molecular Biology and Biotechnology, FORTH, Vassilika Vouton, Heraklion 71110, Crete, Greece
    Genetics 178:2145-60. 2008
    b>Wolbachia-induced cytoplasmic incompatibility (CI) is expressed when infected males are crossed with either uninfected females or females infected with Wolbachia of different CI specificity...
  41. ncbi Long PCR improves Wolbachia DNA amplification: wsp sequences found in 76% of sixty-three arthropod species
    A Jeyaprakash
    Department of Entomology and Nematology, University of Florida, Gainesville, Florida 32611, USA
    Insect Mol Biol 9:393-405. 2000
    Bacteria belonging to the genus Wolbachia are associated with a variety of reproductive anomalies in arthropods. Allele-specific polymerase chain reaction (= Standard PCR) routinely has been used to amplify Wolbachia DNA from arthropods...
  42. ncbi Intense transpositional activity of insertion sequences in an ancient obligate endosymbiont
    Richard Cordaux
    CNRS UMR 6556 Ecologie, Evolution, Symbiose, Universite de Poitiers, Poitiers, France
    Mol Biol Evol 25:1889-96. 2008
    ..Yet, the genome of Wolbachia, one of the most abundant bacterial endosymbionts on Earth, is littered with IS...
  43. ncbi Endosymbiont DNA in endobacteria-free filarial nematodes indicates ancient horizontal genetic transfer
    Samantha N McNulty
    Infectious Diseases Division, Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri, USA
    PLoS ONE 5:e11029. 2010
    b>Wolbachia are among the most abundant symbiotic microbes on earth; they are present in about 66% of all insect species, some spiders, mites and crustaceans, and most filarial nematode species...
  44. ncbi Pathogenesis and host responses in human onchocerciasis: impact of Onchocerca filariae and Wolbachia endobacteria
    N W Brattig
    Tropical Medicine Section, Bernhard Nocht Institute for Tropical Medicine, Bernhard Nocht Strasse 74, 20359, Hamburg, Germany
    Microbes Infect 6:113-28. 2004
    ..The filariae habour abundant intracellular Wolbachia bacteria, now recognised as obligatory symbionts, and therefore emerging as a novel target for chemotherapy...
  45. ncbi A Survey of the bacteriophage WO in the endosymbiotic bacteria Wolbachia
    Laurent Gavotte
    Laboratoire de Biométrie et Biologie Évolutive UMR 5558, CNRS, IFR 41, University Lyon 1, Villeurbanne, France
    Mol Biol Evol 24:427-35. 2007
    ..However, Wolbachia, an intracellular alpha-proteobacterium, infecting diverse arthropod and nematode species and best known for the ..
  46. ncbi ISWpi1 from Wolbachia pipientis defines a novel group of insertion sequences within the IS5 family
    Richard Cordaux
    Laboratoire de Génétique et Biologie des Populations de Crustacés, CNRS UMR 6556, Universite de Poitiers, 40 Avenue du Recteur Pineau, 86022 Poitiers, France
    Gene 409:20-7. 2008
    ..which the taxonomic distribution appears to be restricted to the obligate intracellular alpha-Proteobacterium Wolbachia pipientis...
  47. ncbi Bacteriophage WO and virus-like particles in Wolbachia, an endosymbiont of arthropods
    S Masui
    Department of Biological Sciences, Graduate School of Science, University of Tokyo, Hongo, Bunkyo ku, Tokyo, 113 0033, Japan
    Biochem Biophys Res Commun 283:1099-104. 2001
    b>Wolbachia are intracellular symbionts mainly found in arthropods, causing various sexual alterations on their hosts by unknown mechanisms...
  48. ncbi Somatic stem cell niche tropism in Wolbachia
    Horacio M Frydman
    Howard Hughes Medical Institute, Princeton University, Princeton, New Jersey 08540, USA
    Nature 441:509-12. 2006
    b>Wolbachia are intracellular bacteria found in the reproductive tissue of all major groups of arthropods. They are transmitted vertically from the female hosts to their offspring, in a pattern analogous to mitochondria inheritance...
  49. ncbi The rate of recombination in Wolbachia bacteria
    Francis M Jiggins
    Department of Genetics, University of Cambridge, UK
    Mol Biol Evol 19:1640-3. 2002
  50. ncbi Antibiotics and Wolbachia in filarial nematodes: antifilarial activity of rifampicin, oxytetracycline and chloramphenicol against Onchocerca gutturosa, Onchocerca lienalis and Brugia pahangi
    S Townson
    Tropical Parasitic Diseases Unit, Northwick Park Institute for Medical Research, Harrow, UK
    Ann Trop Med Parasitol 94:801-16. 2000
    ..to study the effects of rifampicin and oxytetracycline on filarial tissues and on the endosymbiont bacterium, Wolbachia. When tested in vitro at a concentration of 50...
  51. ncbi Parasitism and mutualism in Wolbachia: what the phylogenomic trees can and cannot say
    Seth R Bordenstein
    Josephine Bay Paul Center, Marine Biological Laboratory, Woods Hole, MA, USA
    Mol Biol Evol 26:231-41. 2009
    ..b>Wolbachia is an inherited obligate, intracellular infection of invertebrates containing taxa that act broadly as both ..
  52. ncbi Coexistence of Wolbachia with Buchnera aphidicola and a secondary symbiont in the aphid Cinara cedri
    Laura Gomez-Valero
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de Valencia, Valencia, Spain
    J Bacteriol 186:6626-33. 2004
    ..previously found to be associated with aphids (PASS, or R type) and an alpha-proteobacterium that belongs to the Wolbachia genus...
  53. ncbi Wolbachia-based technologies for insect pest population control
    Kostas Bourtzis
    Department of Environmental and Natural Resources Management, University of Ioannina, 30100 Agrinio, Greece
    Adv Exp Med Biol 627:104-13. 2008
    b>Wolbachia are a group of obligatory intracellular and maternally inherited bacteria found in many arthropod species, including insects, mites, spiders, springtails, crustaceans, as well as in certain nematodes...
  54. ncbi Wolbachia-induced unidirectional cytoplasmic incompatibility and speciation: mainland-island model
    Arndt Telschow
    Center for Ecological Research, Kyoto University, Kyoto, Japan a telschow ecology kyoto u ac jp
    PLoS ONE 2:e701. 2007
    Bacteria of the genus Wolbachia are among the most common endosymbionts in the world...
  55. ncbi Wolbachia interferes with ferritin expression and iron metabolism in insects
    Natacha Kremer
    Universite de Lyon, Lyon, France
    PLoS Pathog 5:e1000630. 2009
    b>Wolbachia is an intracellular bacterium generally described as being a facultative reproductive parasite. However, Wolbachia is necessary for oogenesis completion in the wasp Asobara tabida...
  56. ncbi Stage-specific proteomic expression patterns of the human filarial parasite Brugia malayi and its endosymbiont Wolbachia
    Sasisekhar Bennuru
    Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 108:9649-54. 2011
    ..The analysis also yielded much of the proteome of Wolbachia, the obligate endosymbiont of Bm that also expressed proteins in a stage-specific manner...
  57. ncbi Widespread recombination throughout Wolbachia genomes
    Laura Baldo
    Department of Biology, University of California, Riverside, USA
    Mol Biol Evol 23:437-49. 2006
    ..Here we investigate the extent of recombination among housekeeping genes of the endosymbiotic bacteria Wolbachia. Four housekeeping genes, gltA, dnaA, ftsZ, and groEL, were sequenced from a sample of 22 strains belonging to ..
  58. ncbi Computational prediction of essential genes in an unculturable endosymbiotic bacterium, Wolbachia of Brugia malayi
    Alexander G Holman
    New England Biolabs, 240 County Road, Ipswich, MA 01938 2723, USA
    BMC Microbiol 9:243. 2009
    b>Wolbachia (wBm) is an obligate endosymbiotic bacterium of Brugia malayi, a parasitic filarial nematode of humans and one of the causative agents of lymphatic filariasis...
  59. ncbi Offsetting effects of Wolbachia infection and heat shock on sperm production in Drosophila simulans: analyses of fecundity, fertility and accessory gland proteins
    R R Snook
    Department of Organismal Biology and Anatomy, The University of Chicago, Illinois 60637, USA
    Genetics 155:167-78. 2000
    Infection in Drosophila simulans with the endocellular symbiont Wolbachia pipientis results in egg lethality caused by failure to properly initiate diploid development (cytoplasmic incompatibility, CI)...
  60. ncbi Wolbachia infections in Anopheles gambiae cells: transcriptomic characterization of a novel host-symbiont interaction
    Grant L Hughes
    The W Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
    PLoS Pathog 7:e1001296. 2011
    The endosymbiotic bacterium Wolbachia is being investigated as a potential control agent in several important vector insect species...
  61. ncbi Generation of a novel Wolbachia infection in Aedes albopictus (Asian tiger mosquito) via embryonic microinjection
    Zhiyong Xi
    Department of Entomology, University of Kentucky, Lexington, KY 40546, USA
    Insect Biochem Mol Biol 35:903-10. 2005
    ..Strategies of vector suppression and replacement are based upon intracellular Wolbachia bacteria, which occur naturally in many insect populations...
  62. ncbi Infectious speciation revisited: impact of symbiont-depletion on female fitness and mating behavior of Drosophila paulistorum
    Wolfgang J Miller
    Laboratories of Genome Dynamics, Center of Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria
    PLoS Pathog 6:e1001214. 2010
    ..candidates fostering symbiont-driven speciation in arthropods are intracellular bacteria belonging to the genus Wolbachia. They are maternally inherited symbionts of many arthropods capable of manipulating host reproductive biology ..
  63. ncbi Finding of male-killing Spiroplasma infecting Drosophila melanogaster in Africa implies transatlantic migration of this endosymbiont
    J E Pool
    Department of Molecular Biology and Genetics, Cornell University, 233 Biotechnology Building, Ithaca, NY 14853, USA
    Heredity (Edinb) 97:27-32. 2006
    ..melanogaster in Brazil, although part of one locus appears to show a recombinant history. Implications for the origin and history of male-killing Spiroplasma in D. melanogaster are discussed...
  64. ncbi Heritable endosymbionts of Drosophila
    Mariana Mateos
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona 85721, USA
    Genetics 174:363-76. 2006
    ..Previous efforts screened relatively few Drosophila lineages, mainly for Wolbachia. We conducted an extensive survey of potentially heritable endosymbionts from any bacterial lineage via PCR ..
  65. ncbi Detection and characterization of Wolbachia infections in Wuchereria bancrofti (Spirurida: Onchocercidae) var. pacifica and Aedes (Stegomyia) polynesiensis (Diptera: Culicidae)
    Catherine Plichart
    Laboratoire de Recherche en Parasitologie Médicale, Institut Louis Malarde, Papeete, Tahiti, French Polynesia
    Am J Trop Med Hyg 73:354-8. 2005
    ..For an alternative strategy to MDA, we investigated the potential role of Wolbachia to control filarial transmission...
  66. ncbi Evidence for recombination between feminizing Wolbachia in the isopod genus Armadillidium
    Sébastien Verne
    Laboratoire de Génétique et Biologie des Populations de Crustacés, UMR CNRS 6556, Universite de Poitiers, 40, avenue du Recteur Pineau, Poitiers Cedex, France
    Gene 397:58-66. 2007
    b>Wolbachia are maternally inherited endosymbiotic alpha-Proteobacteria infecting a wide range of arthropods. Wolbachia induce feminization in many terrestrial isopod species, particularly in the genus Armadillidium (Crustacea, Oniscidea)...
  67. ncbi Wolbachia endosymbiont responsible for cytoplasmic incompatibility in a terrestrial crustacean: effects in natural and foreign hosts
    Y Moret
    , , UMR CNRS 6556, 40 Avenue du Recteur Pineau, F-86022 Poitiers Cedex, France
    Heredity 86:325-32. 2001
    b>Wolbachia bacteria are vertically transmitted endosymbionts that disturb the reproduction of many arthropods thereby enhancing their spread in host populations...
  68. ncbi Ultrastructural and molecular identification of a Wolbachia endosymbiont in a spider, Nephila clavata
    H W Oh
    Insect Resources Laboratory, Korean Collection for Type Cultures, KoreaResearch Institute of Bioscience and Biotechnology, Yusong, Taejon, Korea
    Insect Mol Biol 9:539-43. 2000
    b>Wolbachia-like bacteria were observed in the egg cells of golden orb-weaving spider, Nephila clavata, by means of transmission electron microscopy...
  69. ncbi Distribution and evolution of bacteriophage WO in Wolbachia, the endosymbiont causing sexual alterations in arthropods
    S Masui
    Department of Biological Sciences, Graduate School of Science, University of Tokyo, Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    J Mol Evol 51:491-7. 2000
    b>Wolbachia are obligatory intracellular and maternally inherited bacteria, known to infect many species of arthropod...
  70. ncbi Wolbachia transfer from Rhagoletis cerasi to Drosophila simulans: investigating the outcomes of host-symbiont coevolution
    Markus Riegler
    Institute of Forest Entomology, Forest Pathology and Forest Protection, BOKU University of Natural Resources and Applied Life Sciences, 1190 Vienna, Austria
    Appl Environ Microbiol 70:273-9. 2004
    b>Wolbachia is an endosymbiont of diverse arthropod lineages that can induce various alterations of host reproduction for its own benefice...
  71. ncbi Wolbachia and cytoplasmic incompatibility in the California Culex pipiens mosquito species complex: parameter estimates and infection dynamics in natural populations
    Jason L Rasgon
    Department of Entomology, University of California, Davis, California 95616, USA
    Genetics 165:2029-38. 2003
    Before maternally inherited bacterial symbionts like Wolbachia, which cause cytoplasmic incompatibility (CI; reduced hatch rate) when infected males mate with uninfected females, can be used in a program to control vector-borne diseases ..
  72. ncbi Sequential evolution of a symbiont inferred from the host: Wolbachia and Drosophila simulans
    J William O Ballard
    The Roy J. Carver Center for Comparative Genomics, Department of Biological Science, University of Iowa, USA
    Mol Biol Evol 21:428-42. 2004
    ..64 sampling localities was employed to infer the phylogeography of the maternally inherited alpha-proteobacteria Wolbachia. Phylogenetic analyses, from three symbiont genes and 24 mtDNA genomes (excluding the A + T-rich region), showed ..
  73. ncbi Wolbachia-induced cytoplasmic incompatibility in Japanese populations of Tetranychus urticae (Acari: Tetranychidae)
    Tetsuo Gotoh
    Faculty of Agriculture, Ibaraki University, Ami, Ibaraki, 300 0393, Japan
    Exp Appl Acarol 42:1-16. 2007
    Intracellular bacteria of the genus Wolbachia (alpha Proteobacteria) induce cytoplasmic incompatibility (CI) in many arthropod species, including spider mites, but not all Wolbachia cause CI...
  74. ncbi Wolbachia infection in the newly described Ecuadorian sand flea, Tunga trimamillata
    Andrea Luchetti
    Dipartimento di Biologia Evoluzionistica Sperimentale, Universita di Bologna, Bologna, Italy
    Exp Parasitol 108:18-23. 2004
    b>Wolbachia pipientis is an intracellular endosymbiont producing reproductive alterations in its hosts. This bacterium have been reported in many arthropods and nematodes...
  75. ncbi Wolbachia pipientis in Australian spiders
    Simone M Rowley
    Department of Zoology and Entomology, School of Life Sciences, University of Queensland, St. Lucia, QLD 4072, Australia
    Curr Microbiol 49:208-14. 2004
    b>Wolbachia pipientis is an endosymbiotic bacterium common to arthropods and filarial nematodes. This study presents the first survey and characterization of Wolbachia pipientis that infect spiders...
  76. ncbi Competing selfish genetic elements in the butterfly Hypolimnas bolina
    Sylvain Charlat
    Department of Biology, University College London, 4 Stephenson Way, London NW1 2HE, United Kingdom
    Curr Biol 16:2453-8. 2006
    ..In this paper, we show that spatial heterogeneity in the occurrence of the male-killing Wolbachia wBol1 in the tropical butterfly Hypolimnas bolina is caused by a second infection that can exclude the male-..
  77. ncbi Wolbachia genome integrated in an insect chromosome: evolution and fate of laterally transferred endosymbiont genes
    Naruo Nikoh
    Division of Natural Sciences, The University of the Air, Chiba 261 8586, Japan
    Genome Res 18:272-80. 2008
    ..Here we thoroughly investigated the bacterial genes derived from a Wolbachia endosymbiont on the nuclear genome of the beetle Callosobruchus chinensis...
  78. ncbi The bacterial catalase from filarial DNA preparations derives from common pseudomonad contaminants and not from Wolbachia endosymbionts
    Jeremy Foster
    New England Biolabs, Beverly, MA 01915, USA
    Parasitol Res 94:141-6. 2004
    b>Wolbachia are obligatory endosymbionts in many species of filarial nematodes...
  79. ncbi Disruption of the Wolbachia surface protein gene wspB by a transposable element in mosquitoes of the Culex pipiens complex (Diptera, Culicidae)
    Y O Sanogo
    Illinois Natural History Survey, Champaign, IL 61820, USA
    Insect Mol Biol 16:143-54. 2007
    ..Both Cx. p. quinquefasciatus and Cx. p. pipiens are infected with the endosymbiotic bacteria Wolbachia pipientis...
  80. ncbi Multiple infection with Wolbachia inducing different reproductive manipulations in the butterfly Eurema hecabe
    Masato Hiroki
    Department of Biology, International Christian University, Miataka, Tokyo 181 8585, Japan
    Proc Biol Sci 271:1751-5. 2004
    b>Wolbachia are rickettsial intracellular symbionts of arthropods and nematodes. In arthropods, they act as selfish genetic elements and manipulate host reproduction, including sex-ratio distortion and cytoplasmic incompatibility (CI)...
  81. ncbi Population dynamics of Wolbachia bacterial endosymbionts in Brugia malayi
    Helen F McGarry
    Filariasis Research Laboratory, Molecular and Biochemical Parasitology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK
    Mol Biochem Parasitol 135:57-67. 2004
    The human filarial nematode Brugia malayi contains an endosymbiotic bacterium, Wolbachia. We used real-time quantitative polymerase chain reaction (QPCR) and microscopy to investigate the population dynamics of the bacterium-nematode ..
  82. ncbi Molecular discrimination of Wolbachia in the Culex pipiens complex: evidence for variable bacteriophage hyperparasitism
    Y O Sanogo
    Department of Entomology, University of Kentucky, Lexington, KY, USA
    Insect Mol Biol 13:365-9. 2004
    ..Cytoplasmic incompatibility (CI) caused by endosymbiotic Wolbachia bacteria is thought to play an important role in restricting gene flow and the evolution of the Culex complex...
  83. ncbi Phylogenetic relationships of the Wolbachia of nematodes and arthropods
    Katelyn Fenn
    Institutes of Evolutionary Biology and Immunology and Infection Research, University of Edinburgh, Edinburgh, United Kingdom
    PLoS Pathog 2:e94. 2006
    b>Wolbachia are well known as bacterial symbionts of arthropods, where they are reproductive parasites, but have also been described from nematode hosts, where the symbiotic interaction has features of mutualism...
  84. ncbi Wolbachia transmission dynamics in Formica wood ants
    Lumi Viljakainen
    Department of Biology, PO Box 3000, 90014 University of Oulu, Finland
    BMC Evol Biol 8:55. 2008
    The role of Wolbachia endosymbionts in shaping the mitochondrial diversity of their arthropod host depends on the effects they have on host reproduction and on the mode of transmission of the bacteria...
  85. ncbi Multilocus sequence typing system for the endosymbiont Wolbachia pipientis
    Laura Baldo
    Department of Biology, University of California, 900 University Avenue, Riverside, CA 92521, USA
    Appl Environ Microbiol 72:7098-110. 2006
    The eubacterial genus Wolbachia comprises one of the most abundant groups of obligate intracellular bacteria, and it has a host range that spans the phyla Arthropoda and Nematoda...
  86. ncbi Distribution of the bacterial symbiont Cardinium in arthropods
    Einat Zchori-Fein
    Department of Vegetable Crops, Agricultural Research Organization, Newe Ya ar Research Center, Ramat Yishay, 30095, Israel
    Mol Ecol 13:2009-16. 2004
    ..These arthropods were also screened for the presence of the better-known reproductive manipulator, Wolbachia. Six per cent of the species screened tested positive for Cardinium, compared with 24% positive for Wolbachia...
  87. ncbi Strain-specific quantification of Wolbachia density in Aedes albopictus and effects of larval rearing conditions
    T J Dutton
    Vector Research Group, Liverpool School of Tropical Medicine, Liverpool, UK
    Insect Mol Biol 13:317-22. 2004
    The density of the endosymbiont Wolbachia can influence the expression of the crossing sterilities known as cytoplasmic incompatibility (CI), and also its rate of maternal transmission...
  88. ncbi Fitness advantage and cytoplasmic incompatibility in Wolbachia single- and superinfected Aedes albopictus
    S L Dobson
    Department of Entomology, University of Kentucky, Lexington, KY 40546, USA
    Heredity (Edinb) 93:135-42. 2004
    b>Wolbachia are obligate, maternally inherited, intracellular bacteria that infect numerous insects and other invertebrates...
  89. ncbi Canine onchocercosis in Greece: report of further 20 cases and molecular characterization of the parasite and its Wolbachia endosymbiont
    A Komnenou
    Clinic of Surgery, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, St. Voutyra 11 Street, 546-27 Thessaloniki, Greece
    Vet Parasitol 118:151-5. 2003
    ..removed from Greek dogs and its Wolbachia endosymbionts...
  90. ncbi Incidence of the endosymbionts Wolbachia, Cardinium and Spiroplasma in phytoseiid mites and associated prey
    Monika Enigl
    Institute of Plant Protection, Department of Applied Plant Sciences and Plant Biotechnology, University of Natural Resources and Applied Life Sciences, Peter Jordanstrasse 82, 1190 Vienna, Austria
    Exp Appl Acarol 42:75-85. 2007
    ..We screened 20 strains of 12 agriculturally relevant herbivorous and predatory mite species for infection with Wolbachia, Cardinium and Spiroplasma by the use of PCR...
  91. ncbi High levels of multiple Wolbachia infection and recombination in the ant Formica exsecta
    Max Reuter
    Institute of Ecology, University of Lausanne, Batiment de Biologie, Lausanne, Switzerland
    Mol Biol Evol 20:748-53. 2003
    b>Wolbachia bacteria are intracellular symbionts of many arthropod species. Their spread through host populations is promoted by drastic alterations imposed on their hosts' reproductive physiology...
  92. ncbi Genetic conflicts over sex ratio: mite-endosymbiont interactions
    Filipa Vala
    Institute for Biodiversity and Ecosystem Dynamics, Section of Population Biology, University of Amsterdam, P O Box 94084, Amsterdam 1090 GB, The Netherlands
    Am Nat 161:254-66. 2003
    ..Here we investigate the conflict over sex ratio between the cytoplasmic bacterium Wolbachia and the two-spotted spider mite Tetranychus urticae Koch...
  93. ncbi Intra-individual coexistence of a Wolbachia strain required for host oogenesis with two strains inducing cytoplasmic incompatibility in the wasp Asobara tabida
    Franck Dedeine
    Biometrie et Biologie Evolutive, Universite Claude Bernard Lyon 1, 69 622 Villeurbanne Cedex, France
    Evolution 58:2167-74. 2004
    Cytoplasmically inherited symbiotic Wolbachia bacteria are known to induce a diversity of phenotypes on their numerous arthropod hosts including cytoplasmic incompatibility, male-killing, thelytokous parthenogenesis, and feminization...
  94. ncbi Molecular phylogeny of Wolbachia endosymbionts in Southeast Asian mosquitoes (Diptera: Culicidae) based on wsp gene sequences
    Toon Ruang-areerate
    Center for Vectors and Vector Borne Diseases, Faculty of Science, Mahidol University, Rama 6 Road, Bangkok 10400, Thailand
    J Med Entomol 40:1-5. 2003
    b>Wolbachia are maternally inherited intracellular bacteria that infect a wide range of arthropods and nematodes and are associated with various reproductive abnormalities in their hosts...
  95. ncbi Evolutionary dynamics of a spatially structured host-parasite association: Drosophila innubila and male-killing Wolbachia
    Kelly A Dyer
    Department of Biology, University of Rochester, Rochester, New York 14627, USA
    Evolution 59:1518-28. 2005
    ..and epidemiologically characterize populations of the mycophagous fly Drosophila innubila and its male-killing Wolbachia endosymbiont, with the aim of integrating the local through global nature of this association...
  96. ncbi New names for old strains? Wolbachia wSim is actually wRi
    Inaki Iturbe-Ormaetxe
    Genome Biol 6:401; author reply 401. 2005
  97. ncbi Wolbachia and nuclear-nuclear interactions contribute to reproductive incompatibility in the spider mite Panonychus mori (Acari: Tetranychidae)
    T Gotoh
    Faculty of Agriculture, Ibaraki University, Ami, Ibaraki 300 0393, Japan
    Heredity (Edinb) 94:237-46. 2005
    Maternally transmitted bacteria of the genus Wolbachia are obligate, intracellular symbionts that are responsible for cytoplasmic incompatibility in a wide range of arthropods such as insects and mites...
  98. ncbi Expression and modulation of embryonic male-killing in Drosophila innubila: opportunities for multilevel selection
    Kelly A Dyer
    Department of Biology, University of Rochester, Rochester, New York 14627, USA
    Evolution 59:838-48. 2005
    ..This study uses a male-killing Wolbachia endosymbiont and its host Drosophila innubila to experimentally address the potential for multilevel selection ..
  99. ncbi Electron microscopic and molecular identification of Wolbachia endosymbionts from Onchocerca lupi: implications for therapy
    Z Egyed
    Department of Immunology and Molecular Biology, Department of Wildlife Diseases and Parasitology, Central Veterinary Institute, Budapest, Hungary
    Vet Parasitol 106:75-82. 2002
    It was recently demonstrated that Wolbachia intracellular bacteria (alpha 2 proteobacteria, Rickettsiales) living in filarial nematodes are obligatory symbionts of their hosts...
  100. ncbi The Allonemobius-Wolbachia host-endosymbiont system: evidence for rapid speciation and against reproductive isolation driven by cytoplasmic incompatibility
    Jeremy L Marshall
    Department of Biology, The University of Texas at Arlington, Box 19498, 501 South Nedderman Drive, Arlington, Texas 76019 0498, USA
    Evolution 58:2409-25. 2004
    ..and rapid speciation can be biased by the occurrence of hybridization and reproductive endosymbionts such as Wolbachia. For example, patterns of mitochondrial DNA (mtDNA) variation can be obscured by mitotypes hitchhiking on ..
  101. ncbi Molecular phylogenetic analysis of Onchocerca lupi and its Wolbachia endosymbiont
    Z Egyed
    Department of Immunology and Molecular Biology, Central Veterinary Institute, Budapest, Hungary
    Vet Parasitol 108:153-61. 2002
    ..the 5S ribosomal RNA gene spacer region sequence of the parasite and the 16S ribosomal RNA gene sequence of its Wolbachia endosymbiotic bacteria (Rickettsiales) supported the morphological and biological arguments that O...

Research Grants98

  1. Development of a novel nematode/Wolbachia target
    Clotilde Carlow; Fiscal Year: 2007
    ..Active compounds may also be tested for their effects on other organisms that possess the target. This will provide the basis for discovering a new class of drugs that may be used in veterinary and human medicine. ..
  2. The Role of Wolbachia Endobacteria in River Blindness
    Eric Pearlman; Fiscal Year: 2007
    ..Rickettsia - like Wolbachia bacteria are essential symbionts of the major pathogenic filarial nematode parasites of humans, including the ..
  3. The Role of Wolbachia Endobacteria in River Blindness
    Eric Pearlman; Fiscal Year: 2007
    ..Rickettsia - like Wolbachia bacteria are essential symbionts of the major pathogenic filarial nematode parasites of humans, including the ..
  4. Proximal determinants of risk for tularemia outbreaks
    Sam Telford; Fiscal Year: 2004
    ..previously classified as Wolbachia sp.) common within tissues of dog ticks, Dermacentor variabilis...
  5. The molecular basis of bacteria-host interaction Drosophila melanogaster
    LAURA SERBUS; Fiscal Year: 2007
    One of the most successful intracellular bacteria is Wolbachia, harbored by thousands of arthropods and nematodes. Wolbachia have recently been shown cause blindness in humans upon release from their nematode host Onchocerca volvulus...
  6. Macrofilaricidal Aminoacyl-tRNA Synthetase Inhibitors
    Michael Kron; Fiscal Year: 2005
    ..by this new research program include both the unique AARS expressed in filarial parasites and those within the Wolbachia endosymbiotic bacteria that are essential for worm viability...
  7. Mapping Protein Interactions between Filaria and its Wolbachia Endosymbiont
    Thomas R Unnasch; Fiscal Year: 2010
    ..Most of the human filarial parasite species harbor an endosymbiotic bacterium of the genus Wolbachia. These endo-bacteria are essential, as elimination of the endosymbiont leads to sterilization of the adult ..
  8. Population genetics of transgenes in mosquito vectors
    Fred Gould; Fiscal Year: 2007
    ..3) engineered underdominance, 4) insertion of loaded autonomous transposons, 5) infection with transgenic Wolbachia strains. The potential for using novel transgenic manipulations will be examined with more general models...
  9. Evolutionary genetics of tsetse and its symbionts
    Serap Aksoy; Fiscal Year: 2010
    ..into natural tsetse populations by cytoplasmic incompatibility phenomenon mediated by tsetse's symbiont, Wolbachia. We propose to investigate the biogeography of the human disease vector species, Glossina fuscipes fuscipes, its ..
  10. Evolutionary genetics of tsetse and its symbionts
    Serap Aksoy; Fiscal Year: 2010
    ..into natural tsetse populations by cytoplasmic incompatibility phenomenon mediated by tsetse's symbiont, Wolbachia. We propose to investigate the biogeography of the human disease vector species, Glossina fuscipes fuscipes, its ..
  11. Evolutionary genetics of tsetse and its symbionts
    Serap Aksoy; Fiscal Year: 2009
    ..into natural tsetse populations by cytoplasmic incompatibility phenomenon mediated by tsetse's symbiont, Wolbachia. We propose to investigate the biogeography of the human disease vector species, Glossina fuscipes fuscipes, its ..
  12. REGULATION OF SEX SPECIFIC GENES IN DROSOPHILA
    Thomas Cline; Fiscal Year: 2006
    ..is sought of how and why Sxl functions in germ cells and how the obligate intracellular parasitic bacterium Wolbachia pipientis interacts with it in that cell type...
  13. Eradication of a Primary Filariasis Vector Population at an Endemic Field Site
    STEPHEN LEONARD DOBSON; Fiscal Year: 2010
    ..Here, we propose a novel strategy in which releases of male Ae. polynesiensis mosquitoes infected with Wolbachia bacteria result in the sterilization of female mosquitoes at a field site endemic for filariasis transmission...
  14. Vector Population Modification Using Wolbachia Symbionts
    Stephen Dobson; Fiscal Year: 2006
    DESCRIPTION (provided by the applicant): Intracellular Wolbachia bacteria infect a diverse range of invertebrate hosts, including medically important disease vectors...
  15. Eradication of a Primary Filariasis Vector Population at an Endemic Field Site
    Stephen Dobson; Fiscal Year: 2007
    ..Here, we propose a novel strategy in which releases of male Ae. polynesiensis mosquitoes infected with Wolbachia bacteria result in the sterilization of female mosquitoes at a field site endemic for filariasis transmission...
  16. Vector Population Modification Using Wolbachia Symbionts
    Stephen Dobson; Fiscal Year: 2003
    DESCRIPTION (provided by the applicant): Intracellular Wolbachia bacteria infect a diverse range of invertebrate hosts, including medically important disease vectors...
  17. Genetic basis of WNV vector competence in Culex tarsalis
    Jason Rasgon; Fiscal Year: 2007
    ..This work also has important relevance for bioterrorism issues because it will provide insight into how intrinsic vector genetic factors in mosquito populations affect the epidemiology of a released Category B agent. ..
  18. Genetic basis of WNV vector competence in Culex tarsalis
    Jason L Rasgon; Fiscal Year: 2010
    ..This work also has important relevance for bioterrorism issues because it will provide insight into how intrinsic vector genetic factors in mosquito populations affect the epidemiology of a released Category B agent. ..
  19. Wolbachia as an Agent for Population Replacement in Anopheles Gambiae
    Jason Rasgon; Fiscal Year: 2007
    ..b>Wolbachia are maternally inherited endosymbionts associated with cytoplasmic incompatibility (CI) i.e...
  20. SYNTHESIS AND DEGRADATION OF RIBOSOMES IN THE MOSQUITO
    Ann Fallon; Fiscal Year: 1993
    ..These studies will contribute to an increased understanding of the genetics and physiology of the mosquito, a disease vector with considerable impact on human health and productivity...
  21. SYNTHESIS AND DEGRADATION OF RIBOSOMES IN THE MOSQUITO
    Ann Fallon; Fiscal Year: 1999
    ..These studies will contribute new information and analytical approaches to investigate gene expression and provide molecular infrastructure essential to disruption of disease transmission in genetically transformed mosquitoes. ..
  22. MOSQUITO IMMUNITY FUNCTIONS
    Ann Fallon; Fiscal Year: 2003
    ..The work will include identification of exon-intron organization and recovery of upstream flanking DNA, which will be analyzed for potential regulatory elements. ..
  23. In vitro culture and transformation of Wolbachia from mosquitoes
    Ann Fallon; Fiscal Year: 2007
    ..The intracellular bacterium, Wolbachia pipientis, provides an attractive drive mechanism, because it favors its own transmission through a reproductive ..
  24. SYNTHESIS AND DEGRADATION OF RIBOSOMES IN THE MOSQUITO
    Ann Fallon; Fiscal Year: 2004
    ..These studies provide cloned genes, molecular approaches, and characterization of regulatory processes that can potentially be manipulated to interfere with disease transmission by blood-feeding arthropods. ..
  25. FACTORS AFFECTING GROWTH OF BRUGIA MALAYI IN SCID MICE
    THIRUCHANDURAI RAJAN; Fiscal Year: 2006
    ..More excitingly, they might help us identify the epitope that forms the target of host defense raising the possibility, long-term, of generating an immuno-prophylactic strategy against filarial infections. ..
  26. FACTORS AFFECTING GROWTH OF BRUGIA MALAYI IN SCID MICE
    THIRUCHANDURAI RAJAN; Fiscal Year: 2000
    ..b) the influence of alleles at the Nramp and iNOS loci on murine susceptibility to B. malayi. (c). the role of cytokines controlling the induction of nitric oxide in the resistance of NOD/LtSz-scid mice to B. malayi. ..