zymomonas

Summary

Summary: A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria that is not known to be pathogenic for man, animals, or plants. Its organisms are spoilers for beers and ciders and in sweet English ciders they are the causative agents of a secondary fermentation known as "cider sickness." The species Z. mobilis is used for experiments in molecular genetic studies.

Top Publications

  1. ncbi Cofermentation of glucose, xylose, and arabinose by genomic DNA-integrated xylose/arabinose fermenting strain of Zymomonas mobilis AX101
    Ali Mohagheghi
    Biotechnology Division for Fuels and Chemicals, National Renewable Energy Laboratory, Golden, CO 80401, USA
    Appl Biochem Biotechnol 98:885-98. 2002
  2. ncbi Performance of immobilized Zymomonas mobilis 31821 (pZB5) on actual hydrolysates produced by Arkenol technology
    Tomiaki Yamada
    JGC, Bio Refinery Group, New Business Development Operations, No 2 Project Division, Yokohama, Japan
    Appl Biochem Biotechnol 98:899-907. 2002
  3. ncbi Engineering lactic acid bacteria with pyruvate decarboxylase and alcohol dehydrogenase genes for ethanol production from Zymomonas mobilis
    Nancy N Nichols
    Fermentation Biotechnology Research Unit, National Center for Agricultural Utilization Research, Agricultural Research Service, USDA, 1815 North University Street, Peoria, IL 61604, USA
    J Ind Microbiol Biotechnol 30:315-21. 2003
  4. ncbi Performance of a newly developed integrant of Zymomonas mobilis for ethanol production on corn stover hydrolysate
    Ali Mohagheghi
    National Bioenergy Center National Renewable Energy Laboratory, Golden, CO 80401, USA
    Biotechnol Lett 26:321-5. 2004
  5. ncbi An ethanol-tolerant recombinant Escherichia coli expressing Zymomonas mobilis pdc and adhB genes for enhanced ethanol production from xylose
    Zhanchao Wang
    College of Biological Sciences, China Agricultural University, Beijing 100094, P R China
    Biotechnol Lett 30:657-63. 2008
  6. pmc Paradigm for industrial strain improvement identifies sodium acetate tolerance loci in Zymomonas mobilis and Saccharomyces cerevisiae
    Shihui Yang
    Biosciences Division and BioEnergy Science Center, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA
    Proc Natl Acad Sci U S A 107:10395-400. 2010
  7. pmc Transcriptomic and metabolomic profiling of Zymomonas mobilis during aerobic and anaerobic fermentations
    Shihui Yang
    Biosciences Division and BioEnergy Science Center, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA
    BMC Genomics 10:34. 2009
  8. doi Genome-scale modeling and in silico analysis of ethanologenic bacteria Zymomonas mobilis
    Hanifah Widiastuti
    Department of Chemical and Biomolecular Engineering, National University of Singapore, Singapore, Singapore
    Biotechnol Bioeng 108:655-65. 2011
  9. pmc Heterologous expression and extracellular secretion of cellulolytic enzymes by Zymomonas mobilis
    Jeffrey G Linger
    National Bioenergy Center, National Renewable Energy Laboratory, Golden, CO 80401, USA
    Appl Environ Microbiol 76:6360-9. 2010
  10. pmc Complete genome sequence of the ethanol producer Zymomonas mobilis NCIMB 11163
    Vassili N Kouvelis
    Department of Genetics and Biotechnology, Faculty of Biology, University of Athens, Panepistimiopolis, Ilissia, Athens 15701, Greece
    J Bacteriol 191:7140-1. 2009

Research Grants

Detail Information

Publications198 found, 100 shown here

  1. ncbi Cofermentation of glucose, xylose, and arabinose by genomic DNA-integrated xylose/arabinose fermenting strain of Zymomonas mobilis AX101
    Ali Mohagheghi
    Biotechnology Division for Fuels and Chemicals, National Renewable Energy Laboratory, Golden, CO 80401, USA
    Appl Biochem Biotechnol 98:885-98. 2002
    ..We have previously developed a plasmid-bearing strain of Zymomonas mobilis (206C[pZB301]) capable of cofermenting glucose, xylose, and arabinose to ethanol...
  2. ncbi Performance of immobilized Zymomonas mobilis 31821 (pZB5) on actual hydrolysates produced by Arkenol technology
    Tomiaki Yamada
    JGC, Bio Refinery Group, New Business Development Operations, No 2 Project Division, Yokohama, Japan
    Appl Biochem Biotechnol 98:899-907. 2002
    ..in a flash fermentation reactor in which the performance of National Renewable Energy Laboratory's patented rec-Zymomonas mobilis 31821 (pZB5) after immobilization was investigated...
  3. ncbi Engineering lactic acid bacteria with pyruvate decarboxylase and alcohol dehydrogenase genes for ethanol production from Zymomonas mobilis
    Nancy N Nichols
    Fermentation Biotechnology Research Unit, National Center for Agricultural Utilization Research, Agricultural Research Service, USDA, 1815 North University Street, Peoria, IL 61604, USA
    J Ind Microbiol Biotechnol 30:315-21. 2003
    ..to express pyruvate decarboxylase (PDC) and alcohol dehydrogenase (ADH), encoded by the pdc and adhB genes of Zymomonas mobilis, in lactic acid bacteria...
  4. ncbi Performance of a newly developed integrant of Zymomonas mobilis for ethanol production on corn stover hydrolysate
    Ali Mohagheghi
    National Bioenergy Center National Renewable Energy Laboratory, Golden, CO 80401, USA
    Biotechnol Lett 26:321-5. 2004
    ..Recombinant Zymomonas mobilis 8b, a recently developed integrant of Zymomonas mobilis 31821(pZB5), tolerated acetic acid up to 16 g l(-..
  5. ncbi An ethanol-tolerant recombinant Escherichia coli expressing Zymomonas mobilis pdc and adhB genes for enhanced ethanol production from xylose
    Zhanchao Wang
    College of Biological Sciences, China Agricultural University, Beijing 100094, P R China
    Biotechnol Lett 30:657-63. 2008
    ..Strains JM109 and ET1 were transformed with expression vector pZY507bc containing Zymomonas mobilis alcohol dehydrogenase II (adhB) and pyruvate decarboxylase (pdc) genes, resulting in an ethanol-..
  6. pmc Paradigm for industrial strain improvement identifies sodium acetate tolerance loci in Zymomonas mobilis and Saccharomyces cerevisiae
    Shihui Yang
    Biosciences Division and BioEnergy Science Center, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA
    Proc Natl Acad Sci U S A 107:10395-400. 2010
    ..Here, we characterize a Zymomonas mobilis mutant (AcR) demonstrating sodium acetate tolerance that has potential importance in biofuel development...
  7. pmc Transcriptomic and metabolomic profiling of Zymomonas mobilis during aerobic and anaerobic fermentations
    Shihui Yang
    Biosciences Division and BioEnergy Science Center, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA
    BMC Genomics 10:34. 2009
    b>Zymomonas mobilis ZM4 (ZM4) produces near theoretical yields of ethanol with high specific productivity and recombinant strains are able to ferment both C-5 and C-6 sugars. Z...
  8. doi Genome-scale modeling and in silico analysis of ethanologenic bacteria Zymomonas mobilis
    Hanifah Widiastuti
    Department of Chemical and Biomolecular Engineering, National University of Singapore, Singapore, Singapore
    Biotechnol Bioeng 108:655-65. 2011
    ..Bioethanol has been recognized as a potential alternative energy source. Among various ethanol-producing microbes, Zymomonas mobilis has acquired special attention due to its higher ethanol yield and tolerance...
  9. pmc Heterologous expression and extracellular secretion of cellulolytic enzymes by Zymomonas mobilis
    Jeffrey G Linger
    National Bioenergy Center, National Renewable Energy Laboratory, Golden, CO 80401, USA
    Appl Environ Microbiol 76:6360-9. 2010
    ..In this report, the initial steps toward achieving this goal in the fermentation host Zymomonas mobilis were investigated by expressing heterologous cellulases and subsequently examining the potential to ..
  10. pmc Complete genome sequence of the ethanol producer Zymomonas mobilis NCIMB 11163
    Vassili N Kouvelis
    Department of Genetics and Biotechnology, Faculty of Biology, University of Athens, Panepistimiopolis, Ilissia, Athens 15701, Greece
    J Bacteriol 191:7140-1. 2009
    b>Zymomonas mobilis is an ethanol-producing alphaproteobacterium currently considered a major candidate organism for bioethanol production. Here we report the finished and annotated genome sequence of Z. mobilis subsp...
  11. pmc The Zymomonas mobilis regulator hfq contributes to tolerance against multiple lignocellulosic pretreatment inhibitors
    Shihui Yang
    Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA
    BMC Microbiol 10:135. 2010
    b>Zymomonas mobilis produces near theoretical yields of ethanol and recombinant strains are candidate industrial microorganisms. To date, few studies have examined its responses to various stresses at the gene level...
  12. ncbi Asymmetric alkene reduction by yeast old yellow enzymes and by a novel Zymomonas mobilis reductase
    Andre Muller
    School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales 2052, Australia
    Biotechnol Bioeng 98:22-9. 2007
    ..encoding yeast old yellow enzymes (OYE 1, 2, and 3) and NAD(P)H-dependent 2-cyclohexen-1-one reductase from Zymomonas mobilis (NCR) were expressed separately in Escherichia coli...
  13. doi Optical mapping and sequencing of the Escherichia coli KO11 genome reveal extensive chromosomal rearrangements, and multiple tandem copies of the Zymomonas mobilis pdc and adhB genes
    Peter C Turner
    Department of Microbiology and Cell Biology, University of Florida, Box 110700, Gainesville, FL 32611, USA
    J Ind Microbiol Biotechnol 39:629-39. 2012
    Escherichia coli KO11 (ATCC 55124) was engineered in 1990 to produce ethanol by chromosomal insertion of the Zymomonas mobilis pdc and adhB genes into E. coli W (ATCC 9637)...
  14. ncbi The genome sequence of the ethanologenic bacterium Zymomonas mobilis ZM4
    Jeong Sun Seo
    Macrogen Inc, World Meridian Venture Center, 60 24, Gasan Dong, Seoul 153 781, Korea
    Nat Biotechnol 23:63-8. 2005
    We report the complete genome sequence of Zymomonas mobilis ZM4 (ATCC31821), an ethanologenic microorganism of interest for the production of fuel ethanol...
  15. doi Transcriptome profiling of Zymomonas mobilis under furfural stress
    Ming Xiong He
    Biomass Energy Technology Research Centre, Biogas Institute of Ministry of Agriculture, Section 4 13, Renming Nanlu, Chengdu 610041, China
    Appl Microbiol Biotechnol 95:189-99. 2012
    ..during cellulosic ethanol production, but the molecular mechanisms of tolerance to this inhibitor in Zymomonas mobilis are still unclear...
  16. pmc Genome sequence of the ethanol-producing Zymomonas mobilis subsp. mobilis lectotype strain ATCC 10988
    Katherine M Pappas
    Department of Genetics and Biotechnology, Faculty of Biology, University of Athens, Panepistimiopolis, Ilissia, Athens 15701, Greece
    J Bacteriol 193:5051-2. 2011
    b>Zymomonas mobilis ATCC 10988 is the type strain of the Z. mobilis subsp. mobilis taxon, members of which are some of the most rigorous ethanol-producing bacteria...
  17. doi Cellulosic ethanol production by Zymomonas mobilis harboring an endoglucanase gene from Enterobacter cloacae
    P Thirumalai Vasan
    Department of Biotechnology, Anna University Tiruchirappalli, Tiruchirappalli 620024, Tamil Nadu, India
    Bioresour Technol 102:2585-9. 2011
    ..The cellulase gene was introduced into Zymomonas mobilis strain Microbial Type Culture Collection centre (MTCC) on a plasmid and 0...
  18. pmc Genome sequence of the ethanol-producing Zymomonas mobilis subsp. pomaceae lectotype strain ATCC 29192
    Vassili N Kouvelis
    Department of Genetics and Biotechnology, Faculty of Biology, University of Athens, Panepistimiopolis, Ilissia, Athens 15701, Greece
    J Bacteriol 193:5049-50. 2011
    b>Zymomonas mobilis is an alphaproteobacterium studied for bioethanol production. Different strains of this organism have been hitherto sequenced; they all belong to the Z. mobilis subsp. mobilis taxon...
  19. pmc Metabolic engineering of Escherichia coli for L-tyrosine production by expression of genes coding for the chorismate mutase domain of the native chorismate mutase-prephenate dehydratase and a cyclohexadienyl dehydrogenase from Zymomonas mobilis
    María I Chávez-Béjar
    Departamento de Ingeniería Celular y Biocatálisis, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Apdo Postal 510 3, Cuernavaca, Morelos 62210, Mexico
    Appl Environ Microbiol 74:3284-90. 2008
    The expression of the feedback inhibition-insensitive enzyme cyclohexadienyl dehydrogenase (TyrC) from Zymomonas mobilis and the chorismate mutase domain from native chorismate mutase-prephenate dehydratase (PheA(CM)) from Escherichia ..
  20. ncbi Metabolic engineering of Corynebacterium glutamicum for fuel ethanol production under oxygen-deprivation conditions
    Masayuki Inui
    Research institute of Innovative Technology for the Earth RITE, 9 2 Kizugawadai Kizu, Soraku, Kyoto 619 0292, Japan
    J Mol Microbiol Biotechnol 8:243-54. 2004
    ..A recombinant strain which expressed the Zymomonas mobilis genes coding for pyruvate decarboxylase (pdc) and alcohol dehydrogenase (adhB) was constructed...
  21. pmc The genome-scale metabolic network analysis of Zymomonas mobilis ZM4 explains physiological features and suggests ethanol and succinic acid production strategies
    Kyung Yun Lee
    Metabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical and Biomolecular Engineering BK21 Program, KAIST, 335 Gwahangno, Yuseong Gu, Daejeon 305 701, Republic of Korea
    Microb Cell Fact 9:94. 2010
    b>Zymomonas mobilis ZM4 is a Gram-negative bacterium that can efficiently produce ethanol from various carbon substrates, including glucose, fructose, and sucrose, via the Entner-Doudoroff pathway...
  22. pmc Glutamate versus glutamine exchange swaps substrate selectivity in tRNA-guanine transglycosylase: insight into the regulation of substrate selectivity by kinetic and crystallographic studies
    Naomi Tidten
    Institut fur Pharmazeutische Chemie, Philipps Universitat Marburg, Marbacher Weg 6, 35032 Marburg, Germany
    J Mol Biol 374:764-76. 2007
    ..To investigate selectivity regulation, kinetic data for Zymomonas mobilis Tgt were recorded...
  23. doi Crystal structure analysis and in silico pKa calculations suggest strong pKa shifts of ligands as driving force for high-affinity binding to TGT
    Tina Ritschel
    Institut fur Pharmazeutische Chemie, Philipps Universitat Marburg, Marbacher Weg 6, Marburg, Germany
    Chembiochem 10:716-27. 2009
    ..Docking suggests multiple orientations of these side chains. Obviously, an entropic advantage of the residual mobility experienced by these ligands in the bound state is beneficial and reveals an overall improved protein binding...
  24. ncbi A new target for shigellosis: rational design and crystallographic studies of inhibitors of tRNA-guanine transglycosylase
    U Grädler
    Institut fur Pharmazeutische Chemie, Marbacher Weg 6, Philipps Universitat Marburg, 35032, Germany
    J Mol Biol 306:455-67. 2001
    ..The X-ray structure of Zymomonas mobilis TGT in complex with preQ1 was used to search for new putative inhibitors with the computer program LUDI...
  25. doi How to replace the residual solvation shell of polar active site residues to achieve nanomolar inhibition of tRNA-guanine transglycosylase
    Tina Ritschel
    Institut fur Pharmazeutische Chemie, Philipps Universitat Marburg, Marbacher Weg 6, 35032 Marburg, Germany
    ChemMedChem 4:2012-23. 2009
    ..Furthermore, conformational preferences of attached hydrophobic moieties explain their contribution to a gradual increase in binding affinity...
  26. ncbi Flexible adaptations in the structure of the tRNA-modifying enzyme tRNA-guanine transglycosylase and their implications for substrate selectivity, reaction mechanism and structure-based drug design
    Ruth Brenk
    Institut fur Pharmazeutische Chemie, Philipps Universitat Marburg, Marbacher Weg 6, 35032 Marburg, Germany
    Chembiochem 4:1066-77. 2003
    ..The TGT enzymes of the eubacteria Zymomonas mobilis (Z. mobilis TGT) and Escherichia coli (E...
  27. ncbi Comparative energetics of glucose and xylose metabolism in recombinant Zymomonas mobilis
    H G Lawford
    Department of Biochemistry, University of Toronto, Ontario, Canada
    Appl Biochem Biotechnol 84:277-93. 2000
    Recombinant Zymomonas mobilis CP4:pZB5 was grown with pH control in batch and continuous modes with either glucose or xylose as the sole carbon and energy source...
  28. doi Structures of iron-dependent alcohol dehydrogenase 2 from Zymomonas mobilis ZM4 with and without NAD+ cofactor
    Ji Hyun Moon
    Department of Chemistry and Institute of Basic Sciences, Chonnam National University, 300, Yongbong Dong, Buk Gu, Gwangju 500 757, Korea
    J Mol Biol 407:413-24. 2011
    The ethanologenic bacterium Zymomonas mobilis ZM4 is of special interest because it has a high ethanol yield. This is made possible by the two alcohol dehydrogenases (ADHs) present in Z...
  29. doi Adaptation yields a highly efficient xylose-fermenting Zymomonas mobilis strain
    Manoj Agrawal
    School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, 311 Ferst Drive, Atlanta, Georgia 30332 0100, USA
    Biotechnol Bioeng 108:777-85. 2011
    b>Zymomonas mobilis is a superb ethanol producer with productivity exceeding yeast strains by several fold...
  30. ncbi Cloning and transcriptional analysis of groES and groEL in ethanol-producing bacterium Zymomonas mobilis TISTR 548
    Pornthap Thanonkeo
    Department of Biotechnology, Fermentation Research Center for Value Added Agricultural Product, Faculty of Technology, Khon Kaen University, Khon Kaen 40002, Thailand
    Pak J Biol Sci 10:13-22. 2007
    ..had an affect not only on growth and cell viability of an obligatorily fermentative Gram-negative bacterium Zymomonas mobilis, but also on protein synthesis...
  31. ncbi Altered mRNA expression of hepatic lipogenic enzyme and PPARalpha in rats fed dietary levan from Zymomonas mobilis
    Soon Ah Kang
    Department of Molecular Biotechnology, Bio Molecular Informatics Center, Konkuk University, Seoul 143 701, South Korea
    J Nutr Biochem 17:419-26. 2006
    ....
  32. ncbi Ethanol cycle in an ethanologenic bacterium
    U Kalnenieks
    Institute of Microbiology and Biotechnology, University of Latvia, Kronvalda boulv 4, LV 1586, Riga, Latvia
    FEBS Lett 522:6-8. 2002
    ..performing interconversion between acetaldehyde and ethanol in aerobically growing ethanologenic bacterium Zymomonas mobilis...
  33. ncbi Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase to elucidate the role of serine 103 for enzymatic activity
    U Grädler
    Institut fur Pharmazeutische Chemie, Philipps Universitat Marburg, Germany
    FEBS Lett 454:142-6. 1999
    ..the role of this residue in the catalytic center, we have mutated the corresponding Ser103 of the crystallizable Zymomonas mobilis TGT into alanine...
  34. doi Electron transport and oxidative stress in Zymomonas mobilis respiratory mutants
    Inese Strazdina
    Institute of Microbiology and Biotechnology, University of Latvia, Kronvalda boulv 4, 1586 Riga, Latvia
    Arch Microbiol 194:461-71. 2012
    The ethanol-producing bacterium Zymomonas mobilis is of great interest from a bioenergetic perspective because, although it has a very high respiratory capacity, the respiratory system does not appear to be primarily required for energy ..
  35. doi Biochemical and molecular characterization of NAD(+)-dependent isocitrate dehydrogenase from the ethanologenic bacterium Zymomonas mobilis
    Peng Wang
    The Key Laboratory of Molecular Evolution and Biodiversity, Institute of Molecular Biology and Biotechnology, College of Life Sciences, Anhui Normal University, Wuhu, China
    FEMS Microbiol Lett 327:134-41. 2012
    An isocitrate dehydrogenase from Zymomonas mobilis was overexpressed in Escherichia coli as a fused protein (ZmIDH)...
  36. ncbi Purification, crystallization, and preliminary x-ray diffraction studies of tRNA-guanine transglycosylase from Zymomonas mobilis
    C Romier
    European Molecular Biology Laboratory, Structural Biology Programme, Heidelberg, Germany
    Proteins 24:516-9. 1996
    ..Tgt from Zymomonas mobilis has been purified by crystallization and further recrystallized to obtain single crystals suitable for X-..
  37. doi DNA restriction-modification systems in the ethanologen, Zymomonas mobilis ZM4
    Aidan L Kerr
    The University of New South Wales, Sydney, Australia
    Appl Microbiol Biotechnol 89:761-9. 2011
    ..R-M) systems for more amenable strain development of the alternative industrial ethanologen, Zymomonas mobilis, three gene knockout mutants were constructed...
  38. doi Enhanced production of ethanol from glycerol by engineered Hansenula polymorpha expressing pyruvate decarboxylase and aldehyde dehydrogenase genes from Zymomonas mobilis
    Won Kyung Hong
    Microbe based Fusion Technology Research Center, Jeonbuk Branch Institute, KRIBB, Jeongeup, Jeonbuk 580 185, South Korea
    Biotechnol Lett 32:1077-82. 2010
    ..engineered to express the pdc and adhB genes encoding pyruvate decarboxylase and aldehyde dehydrogenase II from Zymomonas mobilis, respectively, under the control of the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) promoter...
  39. pmc The role of residues glutamate-50 and phenylalanine-496 in Zymomonas mobilis pyruvate decarboxylase
    J M Candy
    Department of Biochemistry, University of Queensland, Brisbane, Australia
    Biochem J 315:745-51. 1996
    ..1.1.1) from Zymomonas mobilis, as a model for this group of enzymes...
  40. pmc Respiratory chain analysis of Zymomonas mobilis mutants producing high levels of ethanol
    Takeshi Hayashi
    Department of Food and Fermentation Science, Faculty of Food and Nutrition, Beppu University, Beppu, Oita, Japan
    Appl Environ Microbiol 78:5622-9. 2012
    We previously isolated respiratory-deficient mutant (RDM) strains of Zymomonas mobilis, which exhibited greater growth and enhanced ethanol production under aerobic conditions. These RDM strains also acquired thermotolerance...
  41. doi Development of a high-throughput method to evaluate the impact of inhibitory compounds from lignocellulosic hydrolysates on the growth of Zymomonas mobilis
    Mary Ann Franden
    National Bioenergy Center, MS3323, National Renewable Energy Laboratory, Golden, CO, 80401, USA
    J Biotechnol 144:259-67. 2009
    ..effects of furfural, hydroxymethylfurfural (HMF), acetate and ethanol on growth rate and final cell densities of Zymomonas mobilis 8b on glucose are presented...
  42. ncbi Ethanol production from cellulosic materials by genetically engineered Zymomonas mobilis
    Hideshi Yanase
    Department of Biotechnology, Tottori University, Tottori, Tottori, 680 8552, Japan
    Biotechnol Lett 27:259-63. 2005
    To confer the ability to ferment cello-oligosaccharides on the ethanol-producing bacterium, Zymomonas mobilis, the beta-glucosidase gene from Ruminococcus albus, tagged at its N-terminal with the 53-amino acid Tat signal peptide from the ..
  43. doi Evaluation and optimization of ethanol production from carob pod extract by Zymomonas mobilis using response surface methodology
    Hossein Vaheed
    Department of Chemistry, Faculty of Arts and Sciences, E M U Magusa, Mersin 10, Turkey
    J Ind Microbiol Biotechnol 38:101-11. 2011
    In this research, ethanol production from carob pod extract (extract) using Zymomonas mobilis with medium optimized by Plackett-Burman (P-B) and response surface methodologies (RSM) was studied. Z...
  44. doi Discovery and characterization of a xylose reductase from Zymomonas mobilis ZM4
    Manoj Agrawal
    School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA 30332 0100, USA
    Biotechnol Lett 33:2127-33. 2011
    ..a byproduct from xylose fermentation, is a major limiting factor in ethanol production from xylose in engineered Zymomonas strains, yet the postulated xylose reductase remains elusive...
  45. ncbi Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate
    Wei Xie
    Department of Biochemistry, School of Molecular and Cellular Biology, University of Illinois at Urbana Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, USA
    Nat Struct Biol 10:781-8. 2003
    ..Addition of 9-deazaguanine (9dzG) to a reaction mixture of Zymomonas mobilis TGT and an RNA substrate allowed us to trap, purify and crystallize a chemically competent covalent ..
  46. ncbi Inhibition of thiamin diphosphate dependent enzymes by 3-deazathiamin diphosphate
    Stephane Mann
    University Chemical Laboratory, Lensfield Road, Cambridge, UKCB2 1EW
    Org Biomol Chem 2:1732-41. 2004
    ..These compounds are both extremely potent inhibitors of pyruvate decarboxylase from Zymomonas mobilis; binding is competitive with TPP and is essentially irreversible even though no covalent linkage is ..
  47. doi Expression, purification and immobilization of the intracellular invertase INVA, from Zymomonas mobilis on crystalline cellulose and Nylon-6
    María de Los Angeles Calixto-Romo
    Departamento de Biotecnologia y Bioingenieria, CINVESTAV IPN Av Instituto Politécnico, Nacional 2508 Col San Pedro Zacatenco, CP 07360, Mexico D F, Mexico
    J Ind Microbiol Biotechnol 35:1455-63. 2008
    This paper presents two immobilization methods for the intracellular invertase (INVA), from Zymomonas mobilis...
  48. pmc Recombinant production of Zymomonas mobilis pyruvate decarboxylase in the haloarchaeon Haloferax volcanii
    Steven J Kaczowka
    Department of Microbiology and Cell Science, University of Florida, Gainesville, FL 32611 0700, USA
    Archaea 1:327-34. 2005
    ..goal of modifying an archaeon to produce bioethanol or other useful products, the pyruvate decarboxylase gene of Zymomonas mobilis (Zm pdc) was expressed in Haloferax volcanii...
  49. ncbi Crystal structure of 1-deoxy-d-xylulose-5-phosphate reductoisomerase from Zymomonas mobilis at 1.9-A resolution
    Stefano Ricagno
    Department of Medical Biochemistry and Biophysics, Division of Molecular Structural Biology, Karolinska Institutet, Scheelevagen 2, S 171 77 Stockholm, Sweden
    Biochim Biophys Acta 1698:37-44. 2004
    ..The structure of the apo-form of this enzyme from Zymomonas mobilis has been solved and refined to 1...
  50. ncbi irrE, an exogenous gene from Deinococcus radiodurans, improves the growth of and ethanol production by a Zymomonas mobilis strain under ethanol and acid stress
    Ying Zhang
    Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing, China
    J Microbiol Biotechnol 20:1156-62. 2010
    ..Here, we present evidence that IrrE acting as a global regulator confers high stress tolerance to a Zymomonas mobilis strain. Expression of the gene protected Z...
  51. ncbi The effect of Zymomonas mobilis culture on experimental Schistosoma mansoni infection
    Juliana de Fátima Macedo Santos
    Department of Antibiotics of the Federal University of Pernambuco, Recife, PE, Brazil
    Rev Soc Bras Med Trop 37:502-4. 2004
    ..A culture of Zymomonas mobilis was orally administered to mice...
  52. ncbi Identification of functionally important amino acid residues in Zymomonas mobilis levansucrase
    Hideshi Yanase
    Department of Biotechnology, Tottori University, Koyamacho minami, Tottori, Tottori 680 8552, Japan
    J Biochem 132:565-72. 2002
    ..4.1.10) from Zymomonas mobilis were analyzed by random mutation and site-directed mutagenesis...
  53. doi NADH dehydrogenase deficiency results in low respiration rate and improved aerobic growth of Zymomonas mobilis
    Uldis Kalnenieks
    Institute of Microbiology and Biotechnology, University of Latvia, Kronvalda boulv 4, LV 1586, Riga, Latvia
    Microbiology 154:989-94. 2008
    The respiratory chain of the ethanol-producing bacterium Zymomonas mobilis is able to oxidize both species of nicotinamide cofactors, NADH and NADPH...
  54. ncbi Cofactor activation and substrate binding in pyruvate decarboxylase. Insights into the reaction mechanism from molecular dynamics simulations
    Mette Alstrup Lie
    Danish National Research Foundation, Center for Catalysis
    Biochemistry 44:14792-806. 2005
    We have performed long-term molecular dynamics simulations of pyruvate decarboxylase from Zymomonas mobilis...
  55. doi Immobilization of the recombinant invertase INVB from Zymomonas mobilis on Nylon-6
    Vanessa Vallejo-Becerra
    Departamento de Biotecnologia y Bioingenieria, CINVESTAV, IPN Av Instituto Politécnico Nacional 2508, Col San Pedro Zacatenco, 07360, Mexico D F, Mexico
    J Ind Microbiol Biotechnol 35:1289-95. 2008
    The recombinant invertase INVB (re-INVB) from Zymomonas mobilis was immobilized on microbeads of Nylon-6, by means of covalent bonding. The enzyme was strongly and successfully bound to the support...
  56. ncbi Ethanol fermentation on the move
    Thomas W Jeffries
    Nat Biotechnol 23:40-1. 2005
  57. ncbi Zymomonas mobilis for fuel ethanol and higher value products
    P L Rogers
    School of Biotechnology and Biomolecular Sciences, UNSW, 2052 Sydney, Australia
    Adv Biochem Eng Biotechnol 108:263-88. 2007
    ..chemicals, and the recent publication of its genome sequence, have provided continuing stimulus for studies on Zymomonas mobilis...
  58. ncbi Physiology of Zymomonas mobilis: some unanswered questions
    Uldis Kalnenieks
    Institute of Microbiology and Biotechnology, Chair of Microbiology and Biotechnology, University of Latvia, Kronvalda boulv 4, Riga, LV 1586, Latvia
    Adv Microb Physiol 51:73-117. 2006
    The ethanol-producing bacterium Zymomonas mobilis can serve as a model organism for the study of rapid catabolism and inefficient energy conversion in bacteria. Some basic aspects of its physiology still remain poorly understood...
  59. ncbi Exchanging the substrate specificities of pyruvate decarboxylase from Zymomonas mobilis and benzoylformate decarboxylase from Pseudomonas putida
    Petra Siegert
    Institute of Molecular Enzyme Technology, Heinrich Heine University of Dusseldorf, Research Centre Julich, D 52426 Jülich, Germany
    Protein Eng Des Sel 18:345-57. 2005
    Pyruvate decarboxylase from Zymomonas mobilis (PDC) and benzoylformate decarboxylase from Pseudomonas putida (BFD) are thiamine diphosphate-dependent enzymes that decarboxylate 2-keto acids...
  60. ncbi Respiratory behaviour of a Zymomonas mobilis adhB::kan(r) mutant supports the hypothesis of two alcohol dehydrogenase isoenzymes catalysing opposite reactions
    U Kalnenieks
    Institute of Microbiology and Biotechnology, University of Latvia, Kronvalda boulv 4, LV 1586, Riga, Latvia
    FEBS Lett 580:5084-8. 2006
    Perturbation of the aerobic steady-state in a chemostat culture of the ethanol-producing bacterium Zymomonas mobilis with a small pulse of ethanol causes a burst of ethanol oxidation, although the reactant ratio of the alcohol ..
  61. ncbi Kinetic modeling to optimize pentose fermentation in Zymomonas mobilis
    Mehmet M Altintas
    Department of Chemical Engineering, University of Colorado, Boulder, Colorado 80309 0424, USA
    Biotechnol Bioeng 94:273-95. 2006
    b>Zymomonas mobilis engineered to express four heterologous enzymes required for xylose utilization ferments xylose along with glucose...
  62. ncbi Performance testing of Zymomonas mobilis metabolically engineered for cofermentation of glucose, xylose, and arabinose
    Hugh G Lawford
    Bio Engineering Laboratory, Department of Biochemistry, University of Toronto, Ontario, Canada
    Appl Biochem Biotechnol 98:429-48. 2002
    ..performance characteristics of the National Renewable Energy Labora-tory's metabolically engineered Zymomonas mobilis using various biomass hydrolysates...
  63. ncbi Site-directed mutagenesis of the ionizable groups in the active site of Zymomonas mobilis pyruvate decarboxylase: effect on activity and pH dependence
    C Y Huang
    Centre for Protein Structure, Function and Engineering, Department of Biochemistry and Molecular Biology, The University of Queensland, Brisbane, Australia
    Eur J Biochem 268:3558-65. 2001
    ..45. We conjecture that the kcat/Km profile reflects the protonation of an alcoholate anion intermediate of the catalytic cycle...
  64. ncbi High resolution crystal structure of pyruvate decarboxylase from Zymomonas mobilis. Implications for substrate activation in pyruvate decarboxylases
    D Dobritzsch
    Department of Medical Biochemistry and Biophysics, Karolinska Institutet S 17177 Stockholm, Sweden
    J Biol Chem 273:20196-204. 1998
    The crystal structure of tetrameric pyruvate decarboxylase from Zymomonas mobilis has been determined at 1.9 A resolution and refined to a crystallographic R-factor of 16.2% and Rfree of 19.7%...
  65. pmc The glutamate uptake regulatory protein (Grp) of Zymomonas mobilis and its relation to the global regulator Lrp of Escherichia coli
    N Peekhaus
    Institut für Biotechnologie I, Forschungszentrum Julich, Germany
    J Bacteriol 177:5140-7. 1995
    After being expressed in Escherichia coli JC5412, which is defective in glutamate transport, a Zymomonas mobilis gene which enabled this strain to grow on glutamate was cloned...
  66. pmc Sequence analysis and overexpression of the Zymomonas mobilis tgt gene encoding tRNA-guanine transglycosylase: purification and biochemical characterization of the enzyme
    K Reuter
    Institut fur Biochemie, Universitat Erlangen Nurnberg, Germany
    J Bacteriol 177:5284-8. 1995
    ..A partially sequenced gene upstream of the DNA ligase (lig) gene of the Zymomonas mobilis chromosome shows strong homology to the tgt gene of Escherichia coli (K.B. Shark and T...
  67. ncbi Metabolic state of Zymomonas mobilis in glucose-, fructose-, and xylose-fed continuous cultures as analysed by 13C- and 31P-NMR spectroscopy
    A A de Graaf
    Institut für Biotechnologie I, Forschungszentrum Julich, D 52425 Julich, Germany
    Arch Microbiol 171:371-85. 1999
    ..for the well-known significantly different behaviour of the anaerobic, gram-negative, ethanologenic bacterium Zymomonas mobilis during growth on fructose (i.e...
  68. pmc Development of an arabinose-fermenting Zymomonas mobilis strain by metabolic pathway engineering
    K Deanda
    National Renewable Energy Laboratory, Golden, Colorado 80401, USA
    Appl Environ Microbiol 62:4465-70. 1996
    The substrate fermentation range of the ethanologenic bacterium Zymomonas mobilis was expanded to include the pentose sugar, L-arabinose, which is commonly found in agricultural residues and other lignocellulosic biomass...
  69. ncbi Molecular cloning and characterization of the extracellular sucrase gene (sacC) of Zymomonas mobilis
    R Kannan
    Department of Microbial Technology, School of Biological Sciences, Madurai Kamaraj University, India
    Arch Microbiol 163:195-204. 1995
    The Zymomonas mobilis gene sacC that encodes the extracellular sucrase (protein B46) was cloned and expressed in Escherichia coli...
  70. pmc Imidazole acetol phosphate aminotransferase in Zymomonas mobilis: molecular genetic, biochemical, and evolutionary analyses
    W Gu
    Department of Microbiology and Cell Science, University of Florida, Gainesville 32611
    J Bacteriol 177:1576-84. 1995
    hisH encodes imidazole acetol phosphate (IAP) aminotransferase in Zymomonas mobilis and is located immediately upstream of tyrC, a gene which codes for cyclohexadienyl dehydrogenase...
  71. ncbi Cloning and characterization of a pair of genes that stimulate the production and secretion of Zymomonas mobilis extracellular levansucrase and invertase
    Y Kondo
    Department of Agricultural Chemistry, Faculty of Agriculture, University of Osaka Prefecture, Japan
    Biosci Biotechnol Biochem 58:526-30. 1994
    A 1.7-kb DNA fragment cloned from Zymomonas mobilis genomic DNA complemented the inability to grow on sucrose of a Suc- mutant of Z. mobilis that was deficient in the production of both extracellular levansucrase and invertase...
  72. pmc Molecular characterization of the Zymomonas mobilis enolase (eno) gene
    M E Burnett
    School of Biological Sciences, University of Nebraska, Lincoln 68588 0118
    J Bacteriol 174:6548-53. 1992
    The Zymomonas mobilis gene encoding enolase was cloned by genetic complementation of an Escherichia coli eno mutant...
  73. pmc Expression of the Escherichia coli pmi gene, encoding phosphomannose-isomerase in Zymomonas mobilis, leads to utilization of mannose as a novel growth substrate, which can be used as a selective marker
    P Weisser
    Institut für Biotechnologie 1, Forschungszentrum Julich GmbH, Germany
    Appl Environ Microbiol 62:4155-61. 1996
    Wild-type Zymomonas mobilis can utilize only three substrates (sucrose, glucose, and fructose) as sole carbon sources, which are largely converted into ethanol and carbon dioxide...
  74. ncbi NMR analysis of covalent intermediates in thiamin diphosphate enzymes
    Kai Tittmann
    Martin Luther Universitat Halle Wittenberg, Institut fur Biochemie, Kurt Mothes Strasse 3, D 06099 Halle, Germany
    Biochemistry 42:7885-91. 2003
    ..The application of this method to other ThDP-dependent enzymes provides insight into their specific chemical pathways...
  75. ncbi Analysis of the respiratory chain in Ethanologenic Zymomonas mobilis with a cyanide-resistant bd-type ubiquinol oxidase as the only terminal oxidase and its possible physiological roles
    Kaewta Sootsuwan
    Department of Biological Chemistry, Faculty of Agriculture, Yamaguchi University, Yamaguchi, Japan
    J Mol Microbiol Biotechnol 14:163-75. 2008
    The respiratory chain of the ethanologenic bacterium Zymomonas mobilis was investigated, in which the pyruvate-to-ethanol pathway has been demonstrated to be mainly responsible for NADH oxidation and the tricarboxylic acid cycle is ..
  76. ncbi An allosterically insensitive class of cyclohexadienyl dehydrogenase from Zymomonas mobilis
    G Zhao
    Department of Microbiology and Cell Science, University of Florida, Gainesville 32611 0100
    Eur J Biochem 212:157-65. 1993
    The key enzyme of tyrosine biosynthesis in many Gram-negative prokaryotes is cyclohexadienyl dehydrogenase. The Zymomonas mobilis gene (tyrC) coding for this enzyme was cloned in Escherichia coli by complementation of a tyrosine ..
  77. doi An in vivo, label-free quick assay for xylose transport in Escherichia coli
    Tingjian Chen
    Department of Chemical Engineering, Tsinghua University, Beijing 100084, China
    Anal Biochem 390:63-7. 2009
    ..XynB was expressed alone or in conjunction with a Zymomonas mobilis glucose facilitator protein (Glf) capable of transporting xylose...
  78. ncbi Isolation of the dxr gene of Zymomonas mobilis and characterization of the 1-deoxy-D-xylulose 5-phosphate reductoisomerase
    S Grolle
    Institut für Biotechnologie 1, Forschungszentrum Julich GmbH, 52425, Julich, Germany
    FEMS Microbiol Lett 191:131-7. 2000
    ..diphosphate biosynthesis, 1-deoxy-D-xylulose 5-phosphate (DXP) reductoisomerase, was cloned and sequenced from Zymomonas mobilis. The deduced amino acid sequence showed the highest identity (48...
  79. ncbi Cloning, sequencing and expression of stress genes from the ethanol-producing bacterium Zymomonas mobilis: the groESL operon
    M F Barbosa
    Department of Microbiology and Cell Science, University of Florida, Gainesville 32611
    Gene 148:51-7. 1994
    b>Zymomonas mobilis is unique among bacteria in its ability to produce high levels of ethanol (EtOH) during fermentation...
  80. ncbi Structure and properties of pyruvate decarboxylase and site-directed mutagenesis of the Zymomonas mobilis enzyme
    J M Candy
    Centre for Protein Structure, Function and Engineering, Department of Biochemistry, University of Queensland, Brisbane 4072, Australia
    Biochim Biophys Acta 1385:323-38. 1998
    ..Here we review its structure and properties with particular emphasis on how site-directed mutagenesis of the enzyme from Zymomonas mobilis has assisted us to understand the function of critical residues.
  81. ncbi High efficiency ethanol fermentation by entrapment of Zymomonas mobilis into LentiKats
    M Rebros
    Faculty of Chemical and Food Technology, Department of Biotechnology, Slovak Technical University, Slovakia
    Lett Appl Microbiol 41:412-6. 2005
    To examine the potential of Zymomonas mobilis entrapped into polyvinylalcohol (PVA) lens-shaped immobilizates in batch and continuous ethanol production.
  82. doi Construction of a novel cell-surface display system for heterologous gene expression in Escherichia coli by using an outer membrane protein of Zymomonas mobilis as anchor motif
    Ming Xiong He
    Sichuan Key Laboratory of Molecular Biology and Biotechnology, Key Laboratory of Resource Biology and Eco environment of Ministry of Education, College of Life Science, Sichuan University, Chengdu 610064, China
    Biotechnol Lett 30:2111-7. 2008
    ..display system was developed in Escherichia coli using omp1, a hypothetical outer membrane protein of Zymomonas mobilis. By using this system, we successfully expressed beta-amylase gene of sweet potato in E. coli...
  83. ncbi Fermentable metabolite of Zymomonas mobilis controls collagen reduction in photoaging skin by improving TGF-beta/Smad signaling suppression
    Hiroshi Tanaka
    Research Laboratories, Nippon Menard Cosmetic Co Ltd, 2 7 Torimi cho, Nishi ku, Nagoya 451 0071, Japan
    Arch Dermatol Res 300:S57-64. 2008
    ..b>Zymomonas mobilis is an alcohol fermentable, gram-negative facultative anaerobic bacterium whose effect on skin tissue is ..
  84. ncbi Ethanol production from hydrolysed agricultural wastes using mixed culture of Zymomonas mobilis and Candida tropicalis
    Sonali Patle
    TERI University, Darbari Seth Block, IHC Complex, Lodhi Road, New Delhi, 110003, India
    Biotechnol Lett 29:1839-43. 2007
    ..of total reducing sugars with the hydrolysates being evaluated for ethanol production using a mixed culture of Zymomonas mobilis and Candida tropicalis...
  85. pmc High-level acetaldehyde production in Lactococcus lactis by metabolic engineering
    Roger S Bongers
    NIZO Food Research, Department of Flavour and Natural Ingredients, P O Box 20, 6710 BA Ede, The Netherlands
    Appl Environ Microbiol 71:1109-13. 2005
    Efficient conversion of glucose to acetaldehyde is achieved by nisin-controlled overexpression of Zymomonas mobilis pyruvate decarboxylase (pdc) and Lactococcus lactis NADH oxidase (nox) in L. lactis...
  86. ncbi Fermentation of molasses by Zymomonas mobilis: effects of temperature and sugar concentration on ethanol production
    M L Cazetta
    Department of Food and Drugs, Londrina State University, Post Box 6001, CEP 86051 990, Londrina PR, Brazil
    Bioresour Technol 98:2824-8. 2007
    Fermentations utilizing strains of Zymomonas mobilis, in place of the traditional yeasts, have been proposed due their ethanol yields being close to theoretical...
  87. pmc Genetic engineering of Zymobacter palmae for production of ethanol from xylose
    Hideshi Yanase
    Department of Biotechnology, Faculty of Engineering, Tottori University, 4 101 Koyamacho minami, Tottori, Tottori, Japan
    Appl Environ Microbiol 73:2592-9. 2007
    ..palmae, where their expression was driven by the Zymomonas mobilis glyceraldehyde-3-phosphate dehydrogenase promoter...
  88. doi Heterologous expression of pyruvate decarboxylase in Geobacillus thermoglucosidasius
    Ann H Thompson
    Division of Biology, Faculty of Natural Sciences, Imperial College London, South Kensington, London SW7 2AZ, UK
    Biotechnol Lett 30:1359-65. 2008
    ..We have demonstrated that Pdc from Zymomonas mobilis can be expressed in an active form in Geobacillus thermoglucosidasius at up to 52 degrees C, while ..
  89. ncbi Zymomonas mobilis as catalyst for the biotechnological production of sorbitol and gluconic acid
    Gilmar Sidney Erzinger
    University of Joinville, Pharmacy School, Santa Catarina, SC, Brazil
    Appl Biochem Biotechnol 129:787-94. 2006
    ..GA) and sorbitol (SOR) was conducted in a batch reactor with free (CTAB-treated or not) or immobilized cells of Zymomonas mobilis...
  90. doi A comparison of simple rheological parameters and simulation data for Zymomonas mobilis fermentation broths with high substrate loading in a 3-L bioreactor
    Byung Hwan Um
    Department of Chemical Engineering, Samuel Ginn College of Engineering, Auburn University, Auburn, AL 36849, USA
    Appl Biochem Biotechnol 145:29-38. 2008
    ..Computational fluid dynamics analysis of bioreactor mixing demonstrates the change in bioreactor mixing with increasing biomass concentration. The portion-loading method is shown to be effective for processing high-solids slurries...
  91. ncbi Improvement of P450(BM-3) whole-cell biocatalysis by integrating heterologous cofactor regeneration combining glucose facilitator and dehydrogenase in E. coli
    Hendrik Schewe
    Biochemical Engineering Group, DECHEMA e V, Karl Winnacker Institut, Theodor Heuss Allee 25, 60486, Frankfurt, Germany
    Appl Microbiol Biotechnol 78:55-65. 2008
    ..a recombinant intracellular NADPH regeneration system through co-expression of a glucose facilitator from Zymomonas mobilis for uptake of unphosphorylated glucose and a NADP(+)-dependent glucose dehydrogenase from Bacillus ..
  92. ncbi Measurement and analysis of intracellular ATP levels in metabolically engineered Zymomonas mobilis fermenting glucose and xylose mixtures
    Juan Carlos Saez-Miranda
    Department of Chemical Engineering, University of Puerto Rico, Mayaguez Campus, P O Box 9046 Mayagüez, Puerto Rico 00681 9046
    Biotechnol Prog 22:359-68. 2006
    Intracellular adenosine-5'-triphosphate (ATP) levels were measured in a metabolically engineered Zymomonas mobilis over the course of batch fermentations of glucose and xylose mixtures...
  93. ncbi High-solid enzymatic hydrolysis and fermentation of solka floc into ethanol
    Byung Hwan Um
    Forest Bioproducts Research Initiative, Department of Chemical Engineering, University of Maine, Orono, Maine 04469, USA
    J Microbiol Biotechnol 18:1257-65. 2008
    ..In this process, commercial enzymes were used in combination with a recombinant strain of Zymomonas mobilis (39679:pZB4L)...
  94. doi Zymomonas mobilis as catalyst for the biotechnological production of sorbitol and gluconic acid
    Gilmar Sidney Erzinger
    Pharmacy School, University of Joinville, Santa Catarina, SC, Brazil
    Appl Biochem Biotechnol 131:787-94. 2006
    ..GA) and sorbitol (SOR) was conducted in a batch reactor with free (CTAB-treated or not) or immobilized cells of Zymomonas mobilis...
  95. pmc Enhanced benzaldehyde tolerance in Zymomonas mobilis biofilms and the potential of biofilm applications in fine-chemical production
    Xuan Zhong Li
    School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia
    Appl Environ Microbiol 72:1639-44. 2006
    ..b>Zymomonas mobilis was used in this study as a model organism to examine the potential of surface-associated biofilms for ..
  96. pmc The role of aspartic acid 143 in E. coli tRNA-guanine transglycosylase: insights from mutagenesis studies and computational modeling
    Katherine Abold Todorov
    Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109 1065, USA
    Biophys J 89:1965-77. 2005
    ..The crystal structure of Zymomonas mobilis TGT with preQ(1) bound suggests that a key aspartate is critically involved in substrate recognition...
  97. ncbi Catalytic activity of zymomonas mobilis extracellular "levan-levansucrase" complex in sucrose medium
    M Bekers
    Institute of Microbiology and Biotechnology, University of Latvia, Kronvalda boulevard 4, LV 1586, Riga, Latvia
    Commun Agric Appl Biol Sci 68:321-4. 2003
    The fructan biosynthesis by ethanol sedimented "levan-levansucrase" complex from Zymomonas mobilis fermentation broth as well as purified levansucrase was investigated...
  98. ncbi The biotechnological production of sorbitol
    M M Silveira
    Universidade de Caxias do Sul Instituto de Biotecnologia CP 1352, 95001 970 Caxias do Sul, RS, Brazil
    Appl Microbiol Biotechnol 59:400-8. 2002
    ..At present, it is produced chemically. The bacterium Zymomonas mobilis is able to produce sorbitol and gluconic acid from fructose and glucose, respectively...
  99. ncbi Evaluation of a recombinant Klebsiella oxytoca strain for ethanol production from cellulose by simultaneous saccharification and fermentation: comparison with native cellobiose-utilising yeast strains and performance in co-culture with thermotolerant yeas
    Helen Golias
    Department of Chemical Engineering, University of Melbourne, Parkville, Victoria, Australia
    J Biotechnol 96:155-68. 2002
    ..investigated, including ethanol-tolerant strains of Saccharomyces pastorianus, Kluyveromyces marxianus and Zymomonas mobilis...
  100. ncbi Cellulosic fuel ethanol: alternative fermentation process designs with wild-type and recombinant Zymomonas mobilis
    Hugh G Lawford
    Bio Engineering Laboratory, Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada M5S 1A8
    Appl Biochem Biotechnol 105:457-69. 2003
    ..with the University of Toronto to test the fermentation performance characteristics of metabolically engineered Zymomonas mobilis created at the National Renewable Energy Laboratory...
  101. pmc Improvement of cellulolytic properties of Clostridium cellulolyticum by metabolic engineering
    Emmanuel Guedon
    Laboratoire de Biochimie des Bactéries Gram Positif, Faculte des Sciences, Universite Henri Poincare, 54506 Vandoeuvre les Nancy Cedex, France
    Appl Environ Microbiol 68:53-8. 2002
    ..accumulation is decreased by heterologous expression of pyruvate decarboxylase and alcohol dehydrogenase from Zymomonas mobilis...

Research Grants5

  1. Phenotype MicroArrays for Drug Toxicity Screening
    Barry Bochner; Fiscal Year: 2003
    ..In future studies (Phase II SBIR) we will expand the technology and scope of reference drugs tested to build a strong predictive database including cell lines representing more tissues and organs. ..
  2. Detection of Bioterrorism Agents with PM Technology
    Barry Bochner; Fiscal Year: 2006
    ..abstract_text> ..
  3. Phenotype MicroArrays for Drug Toxicity Screening
    Barry Bochner; Fiscal Year: 2007
    ....
  4. Phenotype MicroArray Analysis of Fastidious Pathogens
    Barry Bochner; Fiscal Year: 2007
    ..It will be applied in hospital diagnostic work, environmental diagnostic work, bioterrorism monitoring, new drug development, toxicology studies, and in many areas of basic biology research. ..