viridans streptococci

Summary

Summary: A large heterogeneous group of mostly alpha-hemolytic streptococci. They colonize the respiratory tract at birth and generally have a low degree of pathogenicity. This group of species includes STREPTOCOCCUS MITIS; STREPTOCOCCUS MUTANS; STREPTOCOCCUS ORALIS; STREPTOCOCCUS SANGUIS; STREPTOCOCCUS SOBRINUS; and the STREPTOCOCCUS MILLERI GROUP. The latter are often beta-hemolytic and commonly produce invasive pyogenic infections including brain and abdominal abscesses.

Top Publications

  1. ncbi Viridans streptococci in endocarditis and neutropenic sepsis: biofilm formation and effects of antibiotics
    E Presterl
    Department of Medicine I, Division of Infectious Diseases, Medical University of Vienna, Waehringer Guertel 18 20, 1090 Vienna, Austria
    J Antimicrob Chemother 55:45-50. 2005
  2. pmc Rapid identification of viridans streptococci by mass spectrometric discrimination
    C Friedrichs
    Institute for Medical Microbiology and Epidemiology of Infectious Diseases, University of Leipzig, Liebigstr 24, D 04105 Leipzig, Germany
    J Clin Microbiol 45:2392-7. 2007
  3. ncbi Development of broad-range polymerase chain reaction (PCR) bacterial identification in diagnosis of infective endocarditis
    Tomasz Hryniewiecki
    National Institute of Cardiology, Warsaw, Poland
    J Heart Valve Dis 11:870-4. 2002
  4. doi Recent increase in enterococci, viridans streptococci, Pseudomonas spp. and multiresistant strains among haematological patients, with a negative impact on outcome. Results of a 3-year surveillance study at a single institution
    Chiara Cattaneo
    UO Ematologia, Spedali Civili, Universit à di Brescia, Brescia, Italy
    Scand J Infect Dis 42:324-32. 2010
  5. ncbi Viridans streptococci bacteremia in children with malignancy: relevance of species identification and penicillin susceptibility
    Entesar Husain
    Division of Infectious and Immunologic Diseases, BC s Children Hospital, Vancouver, British Columbia, Canada
    Pediatr Infect Dis J 24:563-6. 2005
  6. pmc Viridans streptococci causing community acquired pneumonia
    M Freitas
    Federal University of Para, UFPA, Sao Paulo, Brazil
    Arch Dis Child 91:779-80. 2006
  7. pmc Viridans streptococci isolated by culture from blood of cancer patients: clinical and microbiologic analysis of 50 cases
    Xiang Y Han
    Section of Clinical Microbiology, The University of Texas MD Anderson Cancer Center, Houston, 77030, USA
    J Clin Microbiol 44:160-5. 2006
  8. pmc Glucosyltransferases of viridans streptococci are modulins of interleukin-6 induction in infective endocarditis
    Chia Tung Shun
    Graduate Institute of Microbiology, College of Medicine, National Taiwan University, No 1 Jen Ai Road, 1st Section, Room 713, Taipei, Taiwan
    Infect Immun 73:3261-70. 2005
  9. pmc Antimicrobial susceptibility patterns and macrolide resistance genes of beta-hemolytic viridans group streptococci in a tertiary Korean hospital
    Young Uh
    Department of Laboratory Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea
    J Korean Med Sci 22:791-4. 2007
  10. pmc Identification of clinically relevant viridans streptococci by an oligonucleotide array
    Chao Chien Chen
    Department of Medical Laboratory Science and Biotechnology, School of Medicine, National Cheng Kung University, 1 University Rd, Tainan 701, Taiwan, Republic of China
    J Clin Microbiol 43:1515-21. 2005

Research Grants

Detail Information

Publications191 found, 100 shown here

  1. ncbi Viridans streptococci in endocarditis and neutropenic sepsis: biofilm formation and effects of antibiotics
    E Presterl
    Department of Medicine I, Division of Infectious Diseases, Medical University of Vienna, Waehringer Guertel 18 20, 1090 Vienna, Austria
    J Antimicrob Chemother 55:45-50. 2005
    ..This study examined the in vitro potency for biofilm formation of clinical VGS bloodstream isolates, and the effects of antibiotics on these biofilms...
  2. pmc Rapid identification of viridans streptococci by mass spectrometric discrimination
    C Friedrichs
    Institute for Medical Microbiology and Epidemiology of Infectious Diseases, University of Leipzig, Liebigstr 24, D 04105 Leipzig, Germany
    J Clin Microbiol 45:2392-7. 2007
    b>Viridans streptococci (VS) are responsible for several systemic diseases, such as endocarditis, abscesses, and septicemia...
  3. ncbi Development of broad-range polymerase chain reaction (PCR) bacterial identification in diagnosis of infective endocarditis
    Tomasz Hryniewiecki
    National Institute of Cardiology, Warsaw, Poland
    J Heart Valve Dis 11:870-4. 2002
    ..The study aim was to identify the value of broad-range bacterial PCR in infective endocarditis (IE) of bacterial etiology, and to determine its specificity and sensitivity...
  4. doi Recent increase in enterococci, viridans streptococci, Pseudomonas spp. and multiresistant strains among haematological patients, with a negative impact on outcome. Results of a 3-year surveillance study at a single institution
    Chiara Cattaneo
    UO Ematologia, Spedali Civili, Universit à di Brescia, Brescia, Italy
    Scand J Infect Dis 42:324-32. 2010
    ..9% of MDI. A significant decrease in Staphylococcus aureus (p < 0.001) and an increase in enterococci, viridans streptococci and Pseudomonas spp. (p = 0.004) were observed during the second period...
  5. ncbi Viridans streptococci bacteremia in children with malignancy: relevance of species identification and penicillin susceptibility
    Entesar Husain
    Division of Infectious and Immunologic Diseases, BC s Children Hospital, Vancouver, British Columbia, Canada
    Pediatr Infect Dis J 24:563-6. 2005
    Our aim was to determine the significance of species identification and penicillin susceptibility of viridans streptococci in children with malignancies...
  6. pmc Viridans streptococci causing community acquired pneumonia
    M Freitas
    Federal University of Para, UFPA, Sao Paulo, Brazil
    Arch Dis Child 91:779-80. 2006
    ..of age, presenting to the paediatric emergency room with clinical and radiological findings of pneumonia, viridans streptococci were isolated in 10/33 positive haemocultures as the only microorganism...
  7. pmc Viridans streptococci isolated by culture from blood of cancer patients: clinical and microbiologic analysis of 50 cases
    Xiang Y Han
    Section of Clinical Microbiology, The University of Texas MD Anderson Cancer Center, Houston, 77030, USA
    J Clin Microbiol 44:160-5. 2006
    ..mitis (P = 0.007). These results suggest that S. mitis is the most common cause of viridans streptococcal bacteremia in cancer patients and is more resistant to antibiotics than other species...
  8. pmc Glucosyltransferases of viridans streptococci are modulins of interleukin-6 induction in infective endocarditis
    Chia Tung Shun
    Graduate Institute of Microbiology, College of Medicine, National Taiwan University, No 1 Jen Ai Road, 1st Section, Room 713, Taipei, Taiwan
    Infect Immun 73:3261-70. 2005
    The glucosyltransferases (GTFs) of viridans streptococci, common pathogens of infective endocarditis, are extracellular proteins that convert sucrose into exopolysaccharides and glucans...
  9. pmc Antimicrobial susceptibility patterns and macrolide resistance genes of beta-hemolytic viridans group streptococci in a tertiary Korean hospital
    Young Uh
    Department of Laboratory Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea
    J Korean Med Sci 22:791-4. 2007
    ..The resistance rates to erythromycin and clindamycin of beta-hemolytic VGS seemed to be lower than those of non-beta-hemolytic VGS in our hospital, although cMLSB phenotype carrying erm(B) was dominant in beta-hemolytic VGS...
  10. pmc Identification of clinically relevant viridans streptococci by an oligonucleotide array
    Chao Chien Chen
    Department of Medical Laboratory Science and Biotechnology, School of Medicine, National Cheng Kung University, 1 University Rd, Tainan 701, Taiwan, Republic of China
    J Clin Microbiol 43:1515-21. 2005
    b>Viridans streptococci (VS) are common etiologic agents of subacute infective endocarditis and are capable of causing a variety of pyogenic infections. Many species of VS are difficult to differentiate by phenotypic traits...
  11. ncbi Secretory IgA, salivary peroxidase, and catalase-mediated microbicidal activity during hydrogen peroxide catabolism in viridans streptococci: pathogen coaggregation
    Y Uehara
    Department of General Medicine, Kochi Medical School, Kohasu Oko cho Nankoku, Japan
    J Infect Dis 194:98-107. 2006
    b>Viridans streptococci can kill methicillin-resistant Staphylococcus aureus (MRSA) through the production of hydrogen peroxide (H2O2). However, several hundred viridans streptococci cells are necessary to kill 1 cfu of MRSA...
  12. ncbi Macrolide resistance can be transferred by conjugation from viridans streptococci to Streptococcus pyogenes
    Maria Jonsson
    Department of Medical Biochemistry and Microbiology, Uppsala University Biomedical Centre, Box 582, SE 751 23 Uppsala, Sweden
    Int J Antimicrob Agents 28:101-3. 2006
    ..We present data indicating conjugative transfer of the mef(E) gene from viridans streptococci to the pathogen Streptococcus pyogenes...
  13. pmc Accuracy of phenotypic and genotypic testing for identification of Streptococcus pneumoniae and description of Streptococcus pseudopneumoniae sp. nov
    Judy C Arbique
    Department of Microbiology, Division of Pathology and Laboratory Medicine, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada
    J Clin Microbiol 42:4686-96. 2004
    ..pneumoniae. Genetic tests for pneumolysin (ply) and manganese-dependent superoxide dismutase (sodA) and identification tests with a commercial probe, AccuProbe Pneumococcus, do not discriminate between the new species and S. pneumoniae...
  14. ncbi Antimicrobial susceptibility patterns and macrolide resistance genes of viridans group streptococci from blood cultures in Korea
    Young Uh
    Department of Laboratory Medicine, Yonsei University Wonju College of Medicine, Ilsan dong 162, Wonju, Kangwon Do, South Korea
    J Antimicrob Chemother 53:1095-7. 2004
    ..Our aim was to study the antimicrobial susceptibilities and macrolide resistance mechanisms of viridans group streptococci (VGS) in a Korean tertiary hospital...
  15. ncbi Use of housekeeping gene sequencing for species identification of viridans streptococci
    Pattarachai Kiratisin
    Department of Microbiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
    Diagn Microbiol Infect Dis 51:297-301. 2005
    ..the sequencing of 2 housekeeping genes, zwf and gki, to identify members of the mitis-sanguinis group of viridans streptococci to the species level, with a better discrimination compared with 16S rDNA sequencing...
  16. doi Effect of benzathine penicillin treatment on antibiotic susceptibility of viridans streptococci in oral flora of patients receiving secondary prophylaxis after rheumatic fever
    Efraim Bilavsky
    Department of Pediatrics C, Schneider Children s Medical Center of Israel, Petah Tiqwa, Israel
    J Infect 56:244-8. 2008
    To assess the level of antibiotic resistance of viridans streptococci in the oral flora of children with a history of rheumatic fever, receiving long-term monthly intramuscular benzathine penicillin G prophylaxis.
  17. doi Antibacterial activity of yoghurt against viridans streptococci in vitro
    S Petti
    G Sanarelli Department of Public Health Sciences, Sapienza University, Piazzale Aldo Moro 5, I 00185 Rome, Italy
    Arch Oral Biol 53:985-90. 2008
    ..It is not clear whether this decrease is due to the bactericidal activity of yoghurt or other mechanisms. The present study investigated the differences in susceptibility to yoghurt between several strains of viridans streptococci.
  18. ncbi [Clinical study and analysis of risk factors for mortality in 86 cases of infectious endocarditis in children and adolescents in Argentina: 1988-2000]
    Hugo Paganini
    Servicio de Control Epidemiológico e Infectología, Hospital de Pediatría Profesor Dr Juan P Garrahan, Buenos Aires, Argentina
    Enferm Infecc Microbiol Clin 22:455-61. 2004
    ..IE is a rare infection in children. Scarce reports with large number of patients are published...
  19. ncbi Effects of tigecycline, linezolid and vancomycin on biofilms of viridans streptococci isolates from patients with endocarditis
    E Presterl
    Department of Medicine I, Division of Infectious Diseases and Tropical Medicine, Medical University of Vienna, Vienna, Austria
    Int J Artif Organs 30:798-804. 2007
    ..We investigate the effects of tigecycline, linezolid and vancomycin on biofilms of viridans group streptococci (VGS) isolated from patients with definite native or prosthetic valve endocarditis...
  20. ncbi Severe mitral regurgitation due to infective endocarditis: do not miss the "hole"
    Yoav Turgeman
    Department of Cardiology, Haemek Medical Center, Afula, Israel
    Isr Med Assoc J 6:181-2. 2004
  21. doi Infective endocarditis from Streptococcus viridans associated with colonic carcinoma: a case report
    Chih Yuan Lin
    Department of Surgery, Tri Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China
    J Card Surg 23:263-5. 2008
    ..We describe a 62-year-old male with adenocarcinoma of the sigmoid colon with the presentation of infective endocarditis due to infection by Streptococcus viridans, and we also report on the condition's successful treatment...
  22. ncbi Impact of amoxicillin prophylaxis on the incidence, nature, and duration of bacteremia in children after intubation and dental procedures
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, 1000 Blythe Blvd, PO Box 32861, Charlotte, NC 28232 2861, USA
    Circulation 109:2878-84. 2004
    ....
  23. ncbi Antimicrobial susceptibility of viridans group streptococcal blood isolates to eight antimicrobial agents
    Andrew Smith
    Infection Research Group, Glasgow Dental Hospital and School, 378 Sauchiehall Street, Glasgow, UK
    Scand J Infect Dis 36:259-63. 2004
    ..These findings are of concern in the light of spread of antibiotic resistance genes from S. oralis and S. mitis to the more invasive pneumococcus...
  24. ncbi Streptococcus sinensis may react with Lancefield group F antiserum
    Patrick C Y Woo
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
    J Med Microbiol 53:1083-8. 2004
    ..Among 302 patients with bacteraemia caused by viridans streptococci over a 6-year period, three cases were caused by Streptococcus sinensis (type strain HKU4T, HKU5 and HKU6)...
  25. ncbi [Phenotypes and genetic mechanisms of resistance to macrolides and lincosamides in viridans group streptococci]
    F Artiles Campelo
    Servicio de Microbiologia, Hospital Universitario de Gran Canaria Dr Negrin, Las Palmas de Gran Canaria
    Rev Esp Quimioter 20:317-22. 2007
    ..Coresistance with penicillin was low. These results suggest that screening for macrolide resistance in VGS would be desirable because of the potential transmission of resistance genes to other pathogenic streptococci...
  26. ncbi Jehovah's Witnesses requiring complex urgent cardiothoracic surgery
    Richard L Holt
    Division of Thoracic and Cardiovascular Surgery, University of Florida College of Medicine, Health Science Center, Gainesville, FL 32610 0286, USA
    Ann Thorac Surg 78:695-7. 2004
    ..Cardiopulmonary bypass management, meticulous hemostatic operative technique, and pharmacologic support of hemostasis and erythropoiesis permit this complex surgery...
  27. pmc Distribution of subclasses mefA and mefE of the mefA gene among clinical isolates of macrolide-resistant (M-phenotype) Streptococcus pneumoniae, viridans group streptococci, and Streptococcus pyogenes
    Carmen Ardanuy
    Servicio de Microbiologia Hospital de Bellvitge, Feixa Llarga s n, 08907 L Hospitalet de Llobregat, Barcelona, Spain
    Antimicrob Agents Chemother 49:827-9. 2005
    ..mefA gene among 116 M-phenotype streptococci was as follows: pneumococci (38 strains had mefE and 4 mefA), viridans streptococci (49 mefE and 1 mefA), and Streptococcus pyogenes (24 mefA)...
  28. ncbi Prevention of peritransplantation viridans streptococcal bacteremia with early vancomycin administration: a single-center observational cohort study
    Dana Jaffe
    Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Clin Infect Dis 39:1625-32. 2004
    ..Prevention of this serious complication is therefore a high priority. The objective of this study was to evaluate the effect of early vancomycin administration on rates and outcomes of VSB...
  29. doi Characteristics of Streptococcus bovis endocarditis and its differences with Streptococcus viridans endocarditis
    J Corredoira
    Infectious Disease Unit, Hospital Xeral Calde, Calle Severo Ochoa S N, Lugo 27004, Spain
    Eur J Clin Microbiol Infect Dis 27:285-91. 2008
    ..0001; clindamycin 67% vs. 11%, p < 0.0001; cotrimoxazole 77% vs. 30.5%, p < 0.0001, respectively. IE due to S. bovis is an emergent disease in our environment, presenting different characteristics to those produced by SVG...
  30. ncbi Reduced susceptibility to penicillin of viridans group streptococci in the oral cavity of patients with haematological disease
    K Westling
    Division of Infectious Diseases, Karolinska Institutet, Huddinge University Hospital, Stockholm, Sweden
    Clin Microbiol Infect 10:899-903. 2004
    ....
  31. ncbi Association between rural residency, group D streptococcal endocarditis and colon cancer?
    J Corredoira
    Clin Microbiol Infect 14:190. 2008
  32. ncbi Infection of the post-pneumonectomy space after dental procedures
    C A Dietl
    J Cardiovasc Surg (Torino) 45:521-2. 2004
  33. ncbi [Clinical, echocardiographic and prognostic profile of Streptococcus viridans left-sided endocarditis]
    Javier Lopez
    Servicio de Cardiologia, Instituto de Ciencias del Corazón ICICOR, Hospital Clinico Universitario, Valladolid, Espana
    Rev Esp Cardiol 58:153-8. 2005
    ....
  34. ncbi Viridans group streptococcal infections among children with cancer and the importance of emerging antibiotic resistance
    Lauren Bruckner
    Department of Pediatrics, Division of Hematology Oncology HSCT, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
    Semin Pediatr Infect Dis 17:153-60. 2006
    ....
  35. ncbi Endocarditis from Staphylococcus aureus
    Mortimer Lorber
    JAMA 294:2972; author reply 2972-3. 2005
  36. ncbi Infective endocarditis complicated by large aortic pseudoaneurysm after cardiac surgery
    Nuno Jorge Pelicano
    Cardiology Department, Santa Marta Hospital, Lisbon, Portugal
    Eur J Echocardiogr 7:394-7. 2006
    ..Six months later a huge aortic pseudoaneurysm is diagnosed and she is submitted to a second uneventful surgery. A review is done for the significant features with discussion of diagnosis and therapy...
  37. ncbi [Infective endocarditis in an internal medicine ward]
    Alvaro Hermida Ameijeiras
    Servicio de Medicina Interna, Hospital Clinico, Santiago de Compostela A Coruña, Espana
    Rev Med Chil 135:11-6. 2007
    ..Due to the increasing number of intravenous drug users, subjects with immune deficiencies or with prosthetic valves, infective endocarditis (IE) continues to be prevalent and to have a high mortality...
  38. pmc Garenoxacin treatment of experimental endocarditis caused by viridans group streptococci
    Paloma Anguita-Alonso
    Division of Infectious Diseases, Department of Medicine, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, USA
    Antimicrob Agents Chemother 50:1263-7. 2006
    ....
  39. ncbi Controversies in antibiotic choices for odontogenic infections
    Panagiotis K Stefanopoulos
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 101:697-8. 2006
  40. ncbi Clindamycin in dentistry: is it an effective prophylaxis for endocarditis?
    Inmaculada Tomás
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 101:698-700. 2006
  41. ncbi Conflicting advice
    D Shanson
    Br Dent J 201:613-4; author reply 615. 2006
  42. ncbi Emergence of quinolone resistance among viridans group streptococci isolated from the oropharynx of neutropenic peripheral blood stem cell transplant patients receiving quinolone antimicrobial prophylaxis
    R M Prabhu
    Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Eur J Clin Microbiol Infect Dis 24:832-8. 2005
    ..Quinolone-resistant viridans group streptococci are frequently found in the oropharynx of neutropenic patients after a brief (median, 8 days) exposure to gatifloxacin or moxifloxacin...
  43. ncbi High frequency of isolation of antibiotic-resistant oral Viridans streptococci from children in Kuwait
    V O Rotimi
    Department of Microbiology, Faculty of Medicine, Kuwait University, Safat
    J Chemother 17:493-501. 2005
    ..The difference in the susceptibilities between the species underscores the importance of accurate-identification and the need for surveillance of antimicrobial resistance among clinical isolates in our hospitals...
  44. ncbi Macrolide resistance mechanisms and in vitro susceptibility patterns of viridans group streptococci isolated from blood cultures
    Alper Ergin
    School of Health Services, Hacettepe University, 06100, Ankara, Turkey
    J Antimicrob Chemother 57:139-41. 2006
    ..Our aim was to study the macrolide resistance mechanisms and antimicrobial susceptibilities of viridans group streptococci (VGS) isolated from blood cultures...
  45. ncbi Perspectives on the 2007 AHA Endocarditis Prevention Guidelines
    Thomas J Pallasch
    University of Southern California School of Dentistry, Los Angeles, USA
    J Calif Dent Assoc 35:507-13. 2007
    ..Presented in this article is a summary of the guidelines as well as commentary on the process...
  46. ncbi [Role of some representatives of opportunistic microflora in development of secondary infection in patients with pulmonary tuberculosis]
    L V Ivushkina
    Antibiot Khimioter 49:7-9. 2004
    ..The data on resistance of the strains of Streptococcus viridans group isolated from the pulmonary tuberculosis patients to various antimicrobials including new fluoroquinolones are presented...
  47. ncbi Streptococcus viridans endocarditis from tongue piercing
    Scott D Lick
    Division of Cardiothoracic Surgery, Department of Surgery, University of Texas Medical Branch, Galveston, Texas 77555 0528, USA
    J Emerg Med 29:57-9. 2005
    ..He was treated with a 6-week course of intravenous antibiotics, but eventually required a Ross procedure for progressive aortic insufficiency...
  48. ncbi Temporal trends in infective endocarditis: a population-based study in Olmsted County, Minnesota
    Imad M Tleyjeh
    Department of Medicine, Division of Infectious Diseases, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minn, USA
    JAMA 293:3022-8. 2005
    ..Limited data exist regarding population-based epidemiologic changes in incidence of infective endocarditis (IE)...
  49. ncbi Clinical features and complications of viridans streptococci bloodstream infection in pediatric hemato-oncology patients
    Wan Ting Huang
    Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    J Microbiol Immunol Infect 40:349-54. 2007
    b>Viridans streptococci (VS) are part of the normal flora of humans, but are fast emerging as pathogens causing bacteremia in neutropenic patients...
  50. ncbi Infective endocarditis due to penicillin-resistant viridans group streptococci
    Bettina Knoll
    Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Clin Infect Dis 44:1585-92. 2007
    ..Because of the paucity of data, it has been difficult to define optimal treatment regimens for this syndrome. Thus, recommendations for therapy have largely been made on the basis of consensus opinion...
  51. ncbi mef(A), mef(E) and a new mef allele in macrolide-resistant Streptococcus spp. isolates from Norway
    Maria Sangvik
    Reference Centre for Detection of Antimicrobial Resistance, Department of Microbiology, University Hospital of North Norway, University of Tromsø, N 9037 Tromsø, Norway
    J Antimicrob Chemother 56:841-6. 2005
    To type mef genes in a nationwide collection of clinical isolates of Streptococcus pneumoniae and Streptococcus pyogenes as well as pharyngeal carrier strains of viridans streptococci in Norway.
  52. ncbi Detection of the aminoglycosidestreptothricin resistance gene cluster ant(6)-sat4-aph(3 ')-III in commensal viridans group streptococci
    Paula Cerdá
    Department of Microbiology, Preventive Medicine and Public Health, Zaragoza University School of Medicine, Spain
    Int Microbiol 10:57-60. 2007
    ..The presence of this resistance gene cluster in commensal streptococci suggests an exchange of resistance genes between these bacteria and enterococci or staphylococci...
  53. ncbi Successful ceftriaxone therapy of endocarditis due to penicillin non-susceptible viridans streptococci
    Samuel A Shelburne
    Department of Medicine, Section of Infectious Diseases, Baylor College of Medicine, N 1319, BCM 286, 1 Baylor Plaza, Houston, TX 77030, USA
    J Infect 54:e99-101. 2007
    b>Viridans streptococci are a major cause of infective endocarditis, and penicillin non-susceptibility is increasing in these organisms...
  54. ncbi Predictors of viridans streptococcal shock syndrome in bacteremic children with cancer and stem-cell transplant recipients
    Adam Gassas
    Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada
    J Clin Oncol 22:1222-7. 2004
    ....
  55. ncbi Nosocomial bloodstream infections due to viridans streptococci in haematological and non-haematological patients: species distribution and antimicrobial resistance
    Outi Lyytikainen
    Departments of Infectious Disease Epidemiology and Microbiology, National Public Health Institute, Mannerheimintie 166, 00300 Helsinki
    J Antimicrob Chemother 53:631-4. 2004
    We studied the species distribution and antimicrobial susceptibility of viridans streptococci (VS) isolates causing nosocomial bloodstream infections (BSIs) in Finnish hospitals.
  56. ncbi Susceptibility of viridans group streptococci isolated from dento-alveolar infections to eight antimicrobial agents
    A J Smith
    J Antimicrob Chemother 52:1045-6. 2003
  57. ncbi Visual diagnosis: a 14-year-old male who has fever and rash
    William M Stauffer
    Center for International Health and International Travel Clinic, Regions Hospital, Pediatric Emergency Medicine, University of Minnesota, Minneapolis, MN, USA
    Pediatr Rev 24:424-9. 2003
  58. ncbi Cardiovascular magnetic resonance imaging demonstrates mitral valve endocarditis
    Burkhard Sievers
    Am J Med 115:681-2. 2003
  59. ncbi Gingivitis and toothbrushes: potential roles in viridans streptococcal bacteraemia
    H F Kennedy
    Department of Microbiology, Royal Hospital for Sick Children, Yorkhill NHS Trust, Glasgow, UK
    J Infect 46:67-70. 2003
    ..from an isolate from his mouth, suggesting that gingivitis may have provided a portal of entry for viridans streptococci into the bloodstream...
  60. ncbi Oral bacteria resistant to mercury and to antibiotics are present in children with no previous exposure to amalgam restorative materials
    Derren Ready
    Eastman Dental Hospital, University College London Hospitals NHS Trust, 256 Gray s Inn Road, WC1X 8LD, London, UK
    FEMS Microbiol Lett 223:107-11. 2003
    ....
  61. pmc In vitro activity of telithromycin against viridans group streptococci and Streptococcus bovis isolated from blood: antimicrobial susceptibility patterns in different groups of species
    Iciar Rodriguez-Avial
    Servicio de Microbiologia Clinica, Hospital Clinico San Carlos, Plaza de Cristo Rey s n, 28040 Madrid, Spain
    Antimicrob Agents Chemother 49:820-3. 2005
    ..Heterogeneity in the susceptibility patterns and macrolide resistance phenotypes and genotypes in the different groups of VGS was detected. We found seven telithromycin-resistant S. bovis isolates all harboring the erm(B) gene...
  62. ncbi Three cases of viridans group streptococcal bacteremia in children with febrile neutropenia and literature review
    Vassiliki Danilatou
    Department of Paediatric Haematology Oncology, University Hospital of Heraklion, Heraklion, Crete, Greece
    Scand J Infect Dis 35:873-6. 2003
    ..Prospective, randomized clinical trials of mouth antiseptics are needed to clarify the usefulness, if any, of such measures in the reduction of viridans group streptococcal bacteremia in this group of patients...
  63. ncbi The relative roles of transthoracic compared with transesophageal echocardiography in children with suspected infective endocarditis
    Tilman Humpl
    Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada
    J Am Coll Cardiol 41:2068-71. 2003
    ..The study evaluated the additional benefit of transesophageal echocardiography (TEE) versus transthoracic echocardiography (TTE) in pediatric cases with suspected bacterial endocarditis...
  64. ncbi Streptococcus viridans septicaemia: a comparison study in patients admitted to the departments of infectious diseases and haematology in a university hospital
    Katarina Westling
    Department of Infectious Diseases, Huddinge University Hospital, Karolinska Institutet, Stockholm, Sweden
    Scand J Infect Dis 34:316-9. 2002
    Infective endocarditis caused by viridans streptococci is a well-described disease. Streptococcus viridans is also an important etiologic agent causing septicaemia in neutropenic patients with haematological diseases...
  65. pmc Interleukin 1alpha increases the susceptibility of rabbits to experimental viridans streptococcal endocarditis
    Jacob Dankert
    Department of Medical Microbiology, Academic Medical Center, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands
    Infect Immun 74:947-52. 2006
    ..Leaving the catheter in place after challenge with viridans streptococci predisposed for experimental IE...
  66. doi Penicillin G-resistant viridans group streptococcal endocarditis and interpretation of the American Heart Association's Guidelines for the Treatment of Infective Endocarditis
    Shigeki Fujitani
    University of California Los Angeles UCLA Affiliated Infectious Diseases Fellowship Training Program, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
    Clin Infect Dis 46:1064-6. 2008
    ....
  67. ncbi Penicillin resistance in viridans streptococcal bacteremia is related with high mortality
    Andrea Docze
    Scand J Infect Dis 35:916-7. 2003
  68. ncbi Bacterial endocarditis complicating pregnancy: case report and systematic review of the literature
    Katie Campuzano
    Division of Maternal Fetal Medicine, FG 048, Farmington, CT 06030, USA
    Arch Gynecol Obstet 268:251-5. 2003
    ..We report a pregnancy complicated by a 3.5-cm infected vegetation of the tricuspid valve initially presenting as unilateral hip pain as well as systematic review of this entity...
  69. doi Bacteriology of external ocular infections in Aba, South Eastern Nigeria
    Udo Ahanna Ubani
    Optometry, Abia State University, Uturu Abia State, Nigeria
    Clin Exp Optom 92:482-9. 2009
    ..Bacteria are microbial agents that frequently cause infections of the eye and possible loss of vision...
  70. doi Viridans streptococcal (Streptococcus intermedius) mitral valve subacute bacterial endocarditis (SBE) in a patient with mitral valve prolapse after a dental procedure: the importance of antibiotic prophylaxis
    Burke A Cunha
    Infectious Disease Division, Winthrop University Hospital, Mineola, New York 11501, USA
    Heart Lung 39:64-72. 2010
    ..The most common organisms causing SBE are the viridans streptococci. Viridans streptococci differ in their propensity to cause SBE, which is related to the ability to adhere ..
  71. ncbi Optimisation of the prevention and treatment of bacterial endocarditis
    K A Taubert
    Department of Science and Medicine, American Heart Association, Dallas, Texas 75231, USA
    Drugs Aging 18:415-24. 2001
    ..For oral, dental, respiratory tract, and oesophageal procedures (most often associated with viridans streptococci) the standard antibacterial regimen is oral amoxicillin...
  72. ncbi Epidemiology and antibiotic susceptibility of bacteria causing skin and soft tissue infections in the USA and Europe: a guide to appropriate antimicrobial therapy
    Mark E Jones
    Focus Technologies, Dwarsdijk 30, 3612AP Tienhoven, Netherlands
    Int J Antimicrob Agents 22:406-19. 2003
    ..agalactiae (20.7%, Germany to 10%, Italy and Spain), S. pyogenes (19.2%, France to 11.1%, USA) and viridans streptococci (25.7%, France to 14.1%, Germany). Vancomycin-resistant Enterococcus spp...
  73. ncbi Odontogenic bacteria in periodontal disease and resistance patterns to common antibiotics used as treatment and prophylaxis in odontology in Spain
    J R Maestre
    Department of Microbiology, Hospital Central de la Defensa Gomez Ulla, Madrid, Spain
    Rev Esp Quimioter 20:61-7. 2007
    ..38.9% F. nucleatum, 30% Capnocytophaga spp., and 10% Veillonella spp. In this study, amoxicillin-clavulanic acid was the most active antibiotic against all species tested, followed by metronidazole in the case of anaerobes...
  74. ncbi Antimicrobial susceptibility of major pathogens of orofacial odontogenic infections to 11 beta-lactam antibiotics
    T Kuriyama
    Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan
    Oral Microbiol Immunol 17:285-9. 2002
    ..The antimicrobial susceptibilities of viridans streptococci (n = 47), Peptostreptococcus (n = 67), Porphyromonas (n = 18), Fusobacterium (n = 57), black-pigmented ..
  75. pmc Platelet aggregation induced by serotype polysaccharides from Streptococcus mutans
    Jean San Chia
    Department of Microbiology, College of Medicine, National Taiwan University, Taipei, Taiwan, Republic of China
    Infect Immun 72:2605-17. 2004
    Platelet aggregation plays an important role in the pathogenesis of infective endocarditis induced by viridans streptococci or staphylococci...
  76. ncbi Effect of penicillin resistance on presentation and outcome of nonenterococcal streptococcal infective endocarditis
    Ron Bin Hsu
    Department of Surgery, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan, ROC
    Cardiology 105:234-9. 2006
    ..The emergence of strains resistant to penicillin is increasingly recognized worldwide. This study sought to assess the effect of penicillin resistance on presentation and outcome of streptococcal endocarditis...
  77. ncbi Etiology and risk factors of 339 cases of infective endocarditis: report from a 10-year national prospective survey in the Slovak Republic
    V Krcmery
    Dept of Pharmacology, Univ of Trnava School of Public Health at St Elizabeth s Cancer Institute, Bratislava, Slovak Republic
    J Chemother 15:579-83. 2003
    ..0% of cases. The majority of IE were caused by staphylococci (29.2%), 15.0% were due to viridans streptococci, 7.4% due to Enterococcus faecalis, 3.9% due to the HACEK group (Haemophilus spp., Actinobacillus spp...
  78. ncbi Comparative in vitro activity of gemifloxacin, ciprofloxacin, levofloxacin and ofloxacin in a North American surveillance study
    D J Hoban
    Laboratories International for Microbiology Studies, Rolling Meadows, IL, USA
    Diagn Microbiol Infect Dis 40:51-7. 2001
    ..pneumoniae, S. pyogenes, S. agalactiae, viridans streptococci, Enterococcus faecalis, methicillin susceptible Staphylococcus aureus, methicillin resistant S. aureus, S...
  79. ncbi Identification of clinically relevant viridans streptococci by analysis of transfer DNA intergenic spacer length polymorphism
    Y De Gheldre
    Department of Microbiology, Hopital Erasme, Universite Libre de Bruxelles, Belgium
    Int J Syst Bacteriol 49:1591-8. 1999
    ..spacer length polymorphism (tDNA-ILP) for the identification to the species level of clinically relevant viridans streptococci was evaluated with a collection of reference strains of 15 species of the salivarius, anginosus, mitis and ..
  80. ncbi Prospective vancomycin audit in Auckland healthcare hospitals
    D Drinkovic
    Green Lane and National Women s Hospitals, Auckland
    N Z Med J 112:336-9. 1999
    ..The aim of this study was to audit the use of vancomycin in Auckland Healthcare hospitals...
  81. ncbi Evaluation of an automated culture system for detecting bacterial contamination of platelets: an analysis with 15 contaminating organisms
    M E Brecher
    University of North Carolina Hospitals, Chapel Hill, North Carolina 27514, USA
    Transfusion 41:477-82. 2001
    ..Approximately 1 in 2000 platelet components are bacterially contaminated. The time to detection of 15 seeded organisms in platelets recovered from an automated culture system was studied...
  82. ncbi Microbiology and management of acute suppurative thyroiditis in children
    Itzhak Brook
    Department of Pediatrics, School of Medicine, Georgetown University, 4431 Albemarle St NW, Washington, DC 20016, USA
    Int J Pediatr Otorhinolaryngol 67:447-51. 2003
    ..Therapy includes administration of antibiotics effective against the causative pathogen(s). Proper selection of therapy can be guided by culture of the lesion. Surgical drainage may be necessary in case of suppuration...
  83. ncbi Antimicrobial susceptibility of viridans group streptococci in Taiwan with an emphasis on the high rates of resistance to penicillin and macrolides in Streptococcus oralis
    L J Teng
    School of Medical Technology, College of Medicine, National Taiwan University, Taipei
    J Antimicrob Chemother 41:621-7. 1998
    ..The difference in susceptibilities between species of viridans streptococci indicates the importance of accurate identification and the need for continuing surveillance of ..
  84. ncbi Surgical treatment of paraannular aortic abscess
    Kyung Hwan Kim
    Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea
    Heart Surg Forum 9:E506-10. 2006
    ..The purpose of this study is to evaluate the long-term outcome of surgical intervention for aortic paraannular abscess...
  85. ncbi Mixed infection in adult bacterial meningitis
    W N Chang
    Dept of Neurology, Chang Gung Memorial Hospital, Taiwan
    Infection 28:8-12. 2000
    ..3%, 1/12) was not higher than that in adult bacterial meningitis. However, complete recuperation was difficult in adult patients with mixed bacterial meningitis...
  86. ncbi Empirical antimicrobial therapy of acute dentoalveolar abscess
    Stevo Matijević
    Military Medical Academy, Clinic for Maxillofacial, Oral Surgery and Implantology, Belgrade, Serbia
    Vojnosanit Pregl 66:544-50. 2009
    ....
  87. ncbi Septic arthritis due to Streptococcus sanguis
    Inga Mandac
    Merkur, University Hospital, Zagreb, Croatia
    Coll Antropol 34:661-4. 2010
    ..Although viridans group streptococci and Streptococcus sanguis in particular are rare causes of septic arthritis in native joints, they should be considered in the differential diagnosis of periodontal disease...
  88. ncbi Validation of BacT/ALERT plastic culture bottles for use in testing of whole-blood-derived leukoreduced platelet-rich-plasma-derived platelets
    M E Brecher
    University of North Carolina, Chapel Hill, North Carolina 27514, USA
    Transfusion 44:1174-8. 2004
    ..This study validated the BacT/ALERT for use in testing pooled PRP-derived PLTs with nine contaminating organisms...
  89. ncbi Analysis of microbial etiology and mortality in patients with brain abscess
    Kashi N Prasad
    Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh 226014, India
    J Infect 53:221-7. 2006
    ..In a prospective study we determined the predisposing factors and the microbiological profile of brain abscess. We also analyzed the mortality in patients with the type of infections identified...
  90. ncbi The in vitro activity of daptomycin against 514 Gram-positive aerobic clinical isolates
    A King
    Department of Infection, KCL, St Thomas Hospital Campus, London SE1 7EH, UK
    J Antimicrob Chemother 48:219-23. 2001
    ..faecium and L. monocytogenes (MICs = 4 mg/L). Our results indicate that daptomycin MICs are independent of methicillin and vancomycin MICs...
  91. ncbi Paediatric infective endocarditis: 19-year experience at a tertiary care hospital in a developing country
    F F Bitar
    Department of Pediatrics, American University of Beirut, Lebanon
    Acta Paediatr 89:427-30. 2000
    ..Bacterial endocarditis prophylaxis should be emphasized in patients with RHD or pulmonary stenosis...
  92. ncbi Interaction between human polymorphonuclear leukocytes and Streptococcus milleri group bacteria
    Anna Wanahita
    Medical Service, Veterans Affairs Medical Center, Baylor College of Medicine, Houston, TX 77030, USA
    J Infect Dis 185:85-90. 2002
    ..pooled normal human serum, SMG stimulated less chemotaxis than did Staphylococcus aureus, in contrast to viridans streptococci, which caused greater chemotaxis than did S. aureus...
  93. ncbi Bacterial interference in nasopharyngeal bacterial flora of otitis-prone and non-otitis-prone children
    J M Bernstein
    Department of Otolaryngology, State University of New York at Buffalo SUNYAB
    Acta Otorhinolaryngol Belg 48:1-9. 1994
    ..b>Viridans streptococci appeared to be the predominant normal flora in children who are non-otitis prone...
  94. ncbi Endophthalmitis isolates and antibiotic sensitivities: a 6-year review of culture-proven cases
    Matthew S Benz
    Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, Florida, USA
    Am J Ophthalmol 137:38-42. 2004
    ..To investigate the spectrum of organisms causing culture-proven endophthalmitis and their sensitivities to commonly used antimicrobial agents...
  95. ncbi Comparative in vitro potency of amoxycillin-clavulanic acid and four oral agents against recent North American clinical isolates from a global surveillance study
    D J Hoban
    Laboratories International for Microbiology Studies, International Health Management Associates Inc, 2122 Palmer Drive, Schaumburg, IL 60173 3817, USA
    Int J Antimicrob Agents 21:425-33. 2003
    ..pneumoniae and viridans streptococci. Against Enterobacteriaceae amoxycillin-clavulanic acid in general, displayed weak activity with only ..
  96. ncbi Chronic sinusitis in children
    J J Daele
    Department of Otorhinolaryngology, CHR de la Citadelle, , Belgium
    Acta Otorhinolaryngol Belg 51:285-304. 1997
    ....
  97. ncbi Clindamycin versus Unasyn in the treatment of facial cellulitis of odontogenic origin in children
    Demetris E Rush
    Children s Hospital of Michigan and Wayne State University, Detroit, Michigan, USA
    Clin Pediatr (Phila) 46:154-9. 2007
    ..The most common aerobic and facultative organisms were viridans streptococci, Neisseria, and Eikenella species...
  98. ncbi Infective endocarditis in Greece: a changing profile. Epidemiological, microbiological and therapeutic data
    C Loupa
    Evangelismos General Hospital, Athens, Greece
    Clin Microbiol Infect 10:556-61. 2004
    ..Staphylococcus aureus was the most important pathogen, isolated in 22% of cases, followed by viridans streptococci (19%) and coagulase-negative staphylococci (16%). Enterococcus spp...
  99. ncbi Bacteriologic findings in patients with chronic sinusitis
    Luis Antonio Merino
    Laboratory Dr Botello, Corrientes, Argentina
    Ear Nose Throat J 82:798-800, 803-4, 806. 2003
    ..Our study is one of the more extensive reports on the type and prevalence of pathogens in chronic sinusitis that has been published to date...
  100. ncbi Antimicrobial prophylaxis in oral surgery and dental procedures
    Juan Ramón Maestre Vera
    Faculty of Health Sciences, Dentistry Alfonso X el Sabio University, Madrid
    Med Oral Patol Oral Cir Bucal 12:E44-52. 2007
    ....
  101. doi Identification of the cpsA gene as a specific marker for the discrimination of Streptococcus pneumoniae from viridans group streptococci
    Hee Kuk Park
    Department of Microbiology, Chung Ang University College of Medicine, 221 Heukseok dong, Dongjak Gu, Seoul 156 756, Republic of Korea
    J Med Microbiol 59:1146-52. 2010
    ..The primer specificities were evaluated using 49 viridans streptococci including 26 S...

Research Grants67

  1. SALIVARY AMYLASE--ROLE IN DENTAL CARIES PATHOGENESIS
    Narayanan Ramasubbu; Fiscal Year: 2002
    ..g. viridans streptococci) in solution and when bound to hydroxyapatite...
  2. SALIVARY IMMUNE RESPONSE TO COMMENSAL ORAL BACTERIA
    Michael Cole; Fiscal Year: 1993
    ..The Specific Aims are as follows: Aim 1: Determine the incidence of pioneer viridans streptococci producing IgA1 protease...
  3. Microbial Recognition of Sialic Acid Diversity in the Salivary Proteome
    Stefan Ruhl; Fiscal Year: 2010
    ..are expected to shed additional light on the surprisingly narrow tissue and host tropism of certain viridans streptococci, of which some thrive exclusively within the human oral cavity...
  4. Distress, Saliva Composition and Saliva Functions
    JOS BOSCH; Fiscal Year: 2006
    ..g., mucin, cystatin); (3) to determine if the saliva-mediated adherence and aggregation of viridans streptococci (as prototypical early colonizers of the dental plaque) is altered in subjects that experience protracted ..
  5. STREPTOCOCCUS SANGUIS MICROBIAL GENOME PROJECT
    FRANCIS MACRINA; Fiscal Year: 2002
    ..Moreover, S. sanguis and other viridans streptococci of the mouth are emerging as life-threatening bloodstream pathogens in neutropenic patients...
  6. GENETIC ANALYSIS OF ORAL STREPTOCOCCAL BIOFILM FORMATION
    NADARAJAH GANESHKUMAR; Fiscal Year: 2003
    Initial colonization of tooth surfaces by oral viridans streptococci, including Streptococcus gordonii, leads to the eventual formation of biofilms called dental plaque...
  7. Transfusion Medicine/Hemostasis Clinical Trials Network
    Mark Brecher; Fiscal Year: 2007
    ..Two TMH CTN protocols are ongoing at UNC, and it is the intention of the investigators at this site to support new network protocols in the future. UNIVERSITY OF NORTH CAROLINA CHAPEL HILL CRITIQUES ..
  8. World Workshop in Oral Medicine IV
    Peter Lockhart; Fiscal Year: 2005
    ..The proceedings will be published as evidence-based recommendations for best clinical practice in Oral Medicine as well as providing suggestions for future basic science and clinical research. ..
  9. Bacteremia from Dental Extraction vs. Oral Hygiene
    Peter Lockhart; Fiscal Year: 2004
    ..Additionally, we will have unique and critical data for the development of both future research and evidence-based guidelines concerning antibiotic prophylaxis for individuals currently felt to be at risk for DSI. ..
  10. Streptococcal genomics and pathogenesis
    Todd Kitten; Fiscal Year: 2007
    b>Viridans streptococci are the leading cause of infective endocarditis, a serious illness which affects about 22,000 people per year in the US and kills over 2,000...
  11. The oral microbiome during cancer chemotherapy and its role in oral mucositis
    Linda D Strausbaugh; Fiscal Year: 2010
    ..The results will allow us to develop comprehensive preventive approaches to improve the well-being of patients and cancer treatment outcomes. ..
  12. Streptococcal virulence factors in extra-oral disease
    Todd Kitten; Fiscal Year: 2003
    ..S. and kills over 2,000. This disease is caused primarily by viridans streptococci, and among viridans streptococci, primarily by Streptococcus sanguis...
  13. Improved Macaque Safety Model for Topical Microbicides: Post-coital Assessments
    Dorothy Patton; Fiscal Year: 2007
    ..In addition, we will collect parallel assessments, when mating has occurred with a placebo gel (HEC universal placebo) in place. These studies will provide urgently needed data regarding topical microbicide use with coital activity. ..
  14. Streptococcal virulence factors in extra-oral disease
    Todd Kitten; Fiscal Year: 2009
    ..The viridans streptococci as a group and Streptococcus sanguis in particular are a leading cause of this disease...
  15. Effects of Massage on Immune System of Preterm Infants
    Jocelyn Ang; Fiscal Year: 2007
    ..Data from this study could also impact future explorations on potential effects of MT on the immune responses to childhood vaccinations and susceptibility to bacterial and viral infections. ..
  16. Analysis Of Group A Streptococcus-Saliva Interaction
    SAMUEL SHELBURNE; Fiscal Year: 2007
    ..GAS pharyngitis costs an estimated $15 billion/year in the US alone, and as the instigator of rheumatic fever, GAS remains, worldwide, the leading cause of preventable pediatric heart disease. ..
  17. LOCAL IMMUNE RESPONSE IN CHLAMYDIA SALPINGITIS
    Dorothy Patton; Fiscal Year: 2003
    ..trachomatis- induced PID. If one chlamydial antigen is the major cause of the DTH response in PID, diagnostic or immunomodulatory efforts can be directed towards that antigen. ..
  18. Clinical Research and Mentoring in Infectious Disease
    Kent Sepkowitz; Fiscal Year: 2006
    ..abstract_text> ..