streptococcus

Summary

Summary: A genus of gram-positive, coccoid bacteria whose organisms occur in pairs or chains. No endospores are produced. Many species exist as commensals or parasites on man or animals with some being highly pathogenic. A few species are saprophytes and occur in the natural environment.

Top Publications

  1. pmc Avian influenza virus, Streptococcus suis serotype 2, severe acute respiratory syndrome-coronavirus and beyond: molecular epidemiology, ecology and the situation in China
    Ying Ma
    CAS Key Laboratory of Pathogenic Microbiology and Immunology CASPMI, Institute of Microbiology, Chinese Academy of Sciences CAS, Beijing 100101, The People s Republic of China
    Philos Trans R Soc Lond B Biol Sci 364:2725-37. 2009
  2. pmc Evolution of the core and pan-genome of Streptococcus: positive selection, recombination, and genome composition
    Tristan Lefebure
    Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    Genome Biol 8:R71. 2007
  3. pmc Catabolite control protein A controls hydrogen peroxide production and cell death in Streptococcus sanguinis
    Lanyan Zheng
    Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    J Bacteriol 193:516-26. 2011
  4. pmc Streptococcus adherence and colonization
    Angela H Nobbs
    Oral Microbiology Unit, Department of Oral and Dental Science, University of Bristol, Bristol BS1 2LY, United Kingdom
    Microbiol Mol Biol Rev 73:407-50, Table of Contents. 2009
  5. pmc A novel double-tryptophan peptide pheromone controls competence in Streptococcus spp. via an Rgg regulator
    Lauren Mashburn-Warren
    Center for Pharmaceutical Biotechnology, College of Pharmacy, The University of Illinois at Chicago, Chicago, IL 60607, USA
    Mol Microbiol 78:589-606. 2010
  6. pmc Comparative genomic analysis of the Streptococcus dysgalactiae species group: gene content, molecular adaptation, and promoter evolution
    Haruo Suzuki
    Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York
    Genome Biol Evol 3:168-85. 2011
  7. ncbi Rapid killing of Streptococcus pneumoniae with a bacteriophage cell wall hydrolase
    J M Loeffler
    Laboratory of Bacterial Pathogenesis, The Rockefeller University, New York, NY 10021, USA
    Science 294:2170-2. 2001
  8. ncbi Survey of the incidence and aetiology of mastitis on dairy farms in England and Wales
    A J Bradley
    School of Clinical Veterinary Science, University of Bristol, Langford
    Vet Rec 160:253-7. 2007
  9. pmc Genome sequence of Streptococcus gallolyticus: insights into its adaptation to the bovine rumen and its ability to cause endocarditis
    Christophe Rusniok
    Institut Pasteur, Unité de Biologie des Bactéries Intracellulaires, CNRS URA 2171, Paris, France
    J Bacteriol 192:2266-76. 2010
  10. pmc What happened to the streptococci: overview of taxonomic and nomenclature changes
    Richard Facklam
    Streptococcus Laboratory, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Clin Microbiol Rev 15:613-30. 2002

Detail Information

Publications261 found, 100 shown here

  1. pmc Avian influenza virus, Streptococcus suis serotype 2, severe acute respiratory syndrome-coronavirus and beyond: molecular epidemiology, ecology and the situation in China
    Ying Ma
    CAS Key Laboratory of Pathogenic Microbiology and Immunology CASPMI, Institute of Microbiology, Chinese Academy of Sciences CAS, Beijing 100101, The People s Republic of China
    Philos Trans R Soc Lond B Biol Sci 364:2725-37. 2009
    ..bacteria can also expand their host range: a new disease, streptococcal toxic shock syndrome, caused by human Streptococcus suis serotype 2 infection, has been observed in China with 52 human fatalities in two separate outbreaks (1998 ..
  2. pmc Evolution of the core and pan-genome of Streptococcus: positive selection, recombination, and genome composition
    Tristan Lefebure
    Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    Genome Biol 8:R71. 2007
    The genus Streptococcus is one of the most diverse and important human and agricultural pathogens...
  3. pmc Catabolite control protein A controls hydrogen peroxide production and cell death in Streptococcus sanguinis
    Lanyan Zheng
    Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    J Bacteriol 193:516-26. 2011
    b>Streptococcus sanguinis is a commensal oral bacterium producing hydrogen peroxide (H₂O₂) that is dependent on pyruvate oxidase (Spx) activity...
  4. pmc Streptococcus adherence and colonization
    Angela H Nobbs
    Oral Microbiology Unit, Department of Oral and Dental Science, University of Bristol, Bristol BS1 2LY, United Kingdom
    Microbiol Mol Biol Rev 73:407-50, Table of Contents. 2009
    ..Collectively, these surface-bound proteins provide Streptococcus species with a "coat of many colors," enabling multiple intimate contacts and interplays between the bacterial ..
  5. pmc A novel double-tryptophan peptide pheromone controls competence in Streptococcus spp. via an Rgg regulator
    Lauren Mashburn-Warren
    Center for Pharmaceutical Biotechnology, College of Pharmacy, The University of Illinois at Chicago, Chicago, IL 60607, USA
    Mol Microbiol 78:589-606. 2010
    ..Deletion of comR or comS in Streptococcus mutans abolished transformability, as did deletion of the oligopeptide permease subunit oppD, suggesting that ..
  6. pmc Comparative genomic analysis of the Streptococcus dysgalactiae species group: gene content, molecular adaptation, and promoter evolution
    Haruo Suzuki
    Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York
    Genome Biol Evol 3:168-85. 2011
    ..b>Streptococcus dysgalactiae (SD) is comprised of two subspecies: S. dysgalactiae subsp...
  7. ncbi Rapid killing of Streptococcus pneumoniae with a bacteriophage cell wall hydrolase
    J M Loeffler
    Laboratory of Bacterial Pathogenesis, The Rockefeller University, New York, NY 10021, USA
    Science 294:2170-2. 2001
    Nasopharyngeal carriage is the major reservoir for Streptococcus pneumoniae in the community. Although eliminating this reservoir would greatly reduce disease occurrence, no suitable intervention has been available for this purpose...
  8. ncbi Survey of the incidence and aetiology of mastitis on dairy farms in England and Wales
    A J Bradley
    School of Clinical Veterinary Science, University of Bristol, Langford
    Vet Rec 160:253-7. 2007
    ..b>Streptococcus uberis and Escherichia coli were isolated in pure culture from 23.5 per cent and 19...
  9. pmc Genome sequence of Streptococcus gallolyticus: insights into its adaptation to the bovine rumen and its ability to cause endocarditis
    Christophe Rusniok
    Institut Pasteur, Unité de Biologie des Bactéries Intracellulaires, CNRS URA 2171, Paris, France
    J Bacteriol 192:2266-76. 2010
    b>Streptococcus gallolyticus (formerly known as Streptococcus bovis biotype I) is an increasing cause of endocarditis among streptococci and frequently associated with colon cancer. S...
  10. pmc What happened to the streptococci: overview of taxonomic and nomenclature changes
    Richard Facklam
    Streptococcus Laboratory, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Clin Microbiol Rev 15:613-30. 2002
    Since the division of the Streptococcus genus into enterococci, lactococci, and streptococci in 1984, many changes in the nomenclature and taxonomy of the Streptococcus genus have taken place...
  11. ncbi Identification of a genetic determinant responsible for host specificity in Streptococcus thermophilus bacteriophages
    M Duplessis
    Departement de Biochimie et de Microbiologie, Faculte des sciences et de genie, Universite Laval, Quebec, Canada, G1K 7P4
    Mol Microbiol 41:325-36. 2001
    ..aim of this study was to identify the phage genetic determinant (anti-receptor) involved in the recognition of Streptococcus thermophilus hosts. The complete genomic sequence of the lytic S...
  12. pmc Interactions between endocarditis-derived Streptococcus gallolyticus subsp. gallolyticus isolates and human endothelial cells
    Tanja Vollmer
    Institut fur Laboratoriums und Transfusionsmedizin, Herz und Diabeteszentrum Nordrhein Westfalen, Bad Oeynhausen, Germany
    BMC Microbiol 10:78. 2010
    b>Streptococcus gallolyticus subsp. gallolyticus is an important causative agent of infective endocarditis (IE) but the knowledge on virulence factors is limited and the pathogenesis of the infection is poorly understood...
  13. ncbi Assembly of pili in Gram-positive bacteria
    Hung Ton-That
    Committee on Microbiology, University of Chicago, 920 East 58th Street, Chicago, Illinois 60637, USA
    Trends Microbiol 12:228-34. 2004
  14. pmc The changing faces of Streptococcus antigen I/II polypeptide family adhesins
    L Jeannine Brady
    Department of Oral Biology, University of Florida, Gainesville, FL 32610, USA
    Mol Microbiol 77:276-86. 2010
    b>Streptococcus mutans antigen I/II (AgI/II) protein was one of the first cell wall-anchored adhesins identified in Gram-positive bacteria. It mediates attachment of S...
  15. pmc Recent advances in understanding the molecular basis of group B Streptococcus virulence
    Heather C Maisey
    Department of Pediatrics, University of California San Diego, La Jolla, CA 92093 0687, USA
    Expert Rev Mol Med 10:e27. 2008
    Group B Streptococcus commonly colonises healthy adults without symptoms, yet under certain circumstances displays the ability to invade host tissues, evade immune detection and cause serious invasive disease...
  16. pmc Functional analysis of a relA/spoT gene homolog from Streptococcus equisimilis
    U Mechold
    Institute for Molecular Biology, Jena University, Germany
    J Bacteriol 178:1401-11. 1996
    We examined the functional attributes of a gene encountered by sequencing the streptokinase gene region of Streptococcus equisimilis H46A. This gene, originally called rel, here termed relS...
  17. pmc Highly penicillin-resistant multidrug-resistant pneumococcus-like strains colonizing children in Oeiras, Portugal: genomic characteristics and implications for surveillance
    Alexandra S Simões
    Laboratory of Molecular Genetics, Instituto de Tecnologia Quimica e Biologica, Universidade Nova de Lisboa, Oeiras 2780 156, Portugal
    J Clin Microbiol 48:238-46. 2010
    ..all isolates were classified as "streptococci of the mitis group" that, however, were distinct from typical Streptococcus pneumoniae or Streptococcus mitis. A single isolate was identified as Streptococcus pseudopneumoniae...
  18. pmc Bacteriocin diversity in Streptococcus and Enterococcus
    Ingolf F Nes
    Laboratory of Microbial Gene Technology, Norwegian University of Life Sciences, N 1432 As, Norway
    J Bacteriol 189:1189-98. 2007
  19. pmc Complete genome sequencing and analysis of a Lancefield group G Streptococcus dysgalactiae subsp. equisimilis strain causing streptococcal toxic shock syndrome (STSS)
    Yumi Shimomura
    Department of Infectious Diseases, National Center for Global Health and Medicine, 1 21 1 Toyama, Shinjuku ku, Tokyo 162 8655, Japan
    BMC Genomics 12:17. 2011
    b>Streptococcus dysgalactiae subsp. equisimilis (SDSE) causes invasive streptococcal infections, including streptococcal toxic shock syndrome (STSS), as does Lancefield group A Streptococcus pyogenes (GAS)...
  20. ncbi Evaluation of safety and human tolerance of the oral probiotic Streptococcus salivarius K12: a randomized, placebo-controlled, double-blind study
    J P Burton
    BLIS Technologies Ltd, Centre for Innovation, University of Otago, Dunedin, New Zealand
    Food Chem Toxicol 49:2356-64. 2011
    b>Streptococcus salivarius is naturally a predominant member of the human oropharynx and the commercial probiotic strain K12 has been consumed for more than a decade...
  21. pmc Isolation and molecular analysis of the gene cluster for the arginine deiminase system from Streptococcus gordonii DL1
    Yiqian Dong
    Department of Oral Biology, University of Florida, Gainesville, Florida 32610, USA
    Appl Environ Microbiol 68:5549-53. 2002
    ..To initiate a study of the Streptococcus gordonii ADS, the ADS gene cluster was isolated from subgenomic DNA libraries of S...
  22. pmc Etiology and antimicrobial susceptibility of udder pathogens from cases of subclinical mastitis in dairy cows in Sweden
    Ylva Persson
    Department of Animal Health and Antimicrobial Strategies, National Veterinary Institute, SE 75189 Uppsala, Sweden
    Acta Vet Scand 53:36. 2011
    ..The aim was to investigate the microbial panorama and the occurrence of antimicrobial resistance. Moreover, differences between newly infected cows and chronically infected cows were investigated...
  23. pmc Incidence and pathogenic effect of Streptococcus pseudopneumoniae
    Colette Harf-Monteil
    Institute of Bacteriology, UPRES EA 3432, Louis Pasteur University, Strasbourg University Hospital, Strasbourg, France
    J Clin Microbiol 44:2240-1. 2006
    We evaluated the incidence of Streptococcus pseudopneumoniae in clinical isolates by phenotypic methods and DNA-DNA hybridization. The pathogenic role of this organism was investigated with the mouse peritonitis/sepsis model...
  24. pmc Safety assessment of the oral cavity probiotic Streptococcus salivarius K12
    Jeremy P Burton
    BLIS Technologies, Centre for Innovation, University of Otago, P O Box 56, Dunedin, New Zealand
    Appl Environ Microbiol 72:3050-3. 2006
    b>Streptococcus salivarius is a prominent member of the oral microbiota and has excellent potential for use as a probiotic targeting the oral cavity. In this report we document safety data relating to S...
  25. ncbi Novel clues on the specific association of Streptococcus gallolyticus subsp gallolyticus with colorectal cancer
    Annemarie Boleij
    Department of Laboratory Medicine, Nijmegen Institute for Infection, Inflammation and Immunity, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Infect Dis 203:1101-9. 2011
    The prevalence of Streptococcus gallolyticus subsp gallolyticus ( Streptococcus bovis biotype I) endocarditis is in general low but very often linked to colorectal cancer...
  26. pmc Screening for antimicrobial resistance genes and virulence factors via genome sequencing
    Mads Bennedsen
    Innovation, Chr Hansen A S, 10 12 Bøge Allé, DK 2970 Hørsholm, Denmark
    Appl Environ Microbiol 77:2785-7. 2011
    ..No virulence factor genes were detected, while several isolates contained antimicrobial resistance genes...
  27. pmc Macedocin, a food-grade lantibiotic produced by Streptococcus macedonicus ACA-DC 198
    Marina D Georgalaki
    Laboratory of Dairy Research, Department of Food Science and Technology, Agricultural University of Athens, Greece
    Appl Environ Microbiol 68:5891-903. 2002
    b>Streptococcus macedonicus ACA-DC 198, a strain isolated from Greek Kasseri cheese, produces a food-grade lantibiotic named macedocin. Macedocin has a molecular mass of 2,794.76 +/- 0.42 Da, as determined by electrospray mass spectrometry...
  28. ncbi Microbial toxicity of metal oxide nanoparticles (CuO, NiO, ZnO, and Sb2O3) to Escherichia coli, Bacillus subtilis, and Streptococcus aureus
    Yong Wook Baek
    Department of Environmental Science, Konkuk University, 1 Hwayang dong, Gwangjin gu, Seoul 143 701, Republic of Korea
    Sci Total Environ 409:1603-8. 2011
    ..microbial toxicities of metal oxide nanoparticles were evaluated for Escherichia coli, Bacillus subtilis, and Streptococcus aureus in laboratory experiments. The nanoparticles tested were CuO, NiO, ZnO, and Sb(2)O(3)...
  29. ncbi Antibodies to neuron-specific antigens in children with autism: possible cross-reaction with encephalitogenic proteins from milk, Chlamydia pneumoniae and Streptococcus group A
    A Vojdani
    Section of Neuroimmunology, Immunosciences Laboratory, Inc, 8693 Wilshire Boulevard, Suite 200, Beverly Hills, CA 90211, USA
    J Neuroimmunol 129:168-77. 2002
    ..These results suggest a mechanism by which bacterial infections and milk antigens may modulate autoimmune responses in autism...
  30. pmc Diversity and mobility of integrative and conjugative elements in bovine isolates of Streptococcus agalactiae, S. dysgalactiae subsp. dysgalactiae, and S. uberis
    Marisa Haenni
    Unité Antibiorésistance et Virulence Bactériennes, Anses Lyon, 31 avenue Tony Garnier, F 69364 Lyon Cedex 07, France
    Appl Environ Microbiol 76:7957-65. 2010
    Bovine isolates of Streptococcus agalactiae (n = 76), Streptococcus dysgalactiae subsp...
  31. ncbi An accessory sec locus of Streptococcus gordonii is required for export of the surface protein GspB and for normal levels of binding to human platelets
    Barbara A Bensing
    Division of Infectious Diseases, Veterans Affairs Medical Center 111W and the University of California, 4150 Clement Street, San Francisco, CA 94121, USA
    Mol Microbiol 44:1081-94. 2002
    ..However, Streptococcus gordonii strain M99 encodes SecA and SecY homologues that are not required for viability or for the ..
  32. ncbi Antibacterial activity of polyphenol components in oolong tea extract against Streptococcus mutans
    H Sasaki
    Department of Pediatric Dentistry, Osaka University Graduate School of Dentistry, Osaka, Japan
    Caries Res 38:2-8. 2004
    ..study was to determine the antibacterial activity of oolong tea extract on oral streptococci, including Streptococcus mutans and Streptococcus sobrinus, and to identify the response to its components...
  33. ncbi Plasminogen binding by oral streptococci from dental plaque and inflammatory lesions
    Bertil Kinnby
    Department of Oral Biology, Malmo University, S 20506 Malmö, Sweden
    Microbiology 154:924-31. 2008
    ..The findings illustrate how apparently innocuous commensal bacteria are capable of utilizing a mechanism that is generally regarded as being of importance to pathogenicity and suggest an additional role of plasminogen binding...
  34. pmc Intra- and interspecies signaling between Streptococcus salivarius and Streptococcus pyogenes mediated by SalA and SalA1 lantibiotic peptides
    M Upton
    Department of Oral and Dental Science, University of Bristol Dental School, Bristol, BS1 2LY, United Kingdom
    J Bacteriol 183:3931-8. 2001
    b>Streptococcus salivarius 20P3 produces a 22-amino-acid residue lantibiotic, designated salivaricin A (SalA), that inhibits the growth of a range of streptococci, including all strains of Streptococcus pyogenes...
  35. pmc Extent of horizontal gene transfer in evolution of Streptococci of the salivarius group
    Christine Delorme
    Laboratoire de Genetique Microbienne, Institut National de Recherche Agronomique, 78352 Jouy en Josas Cedex, France
    J Bacteriol 189:1330-41. 2007
    The phylogenetically closely related species Streptococcus salivarius and Streptococcus vestibularis are oral bacteria that are considered commensals, although they can also be found in human infections...
  36. ncbi Phylogenetic relationships and genotyping of the genus Streptococcus by sequence determination of the RNase P RNA gene, rnpB
    Jenny Täpp
    Department of Clinical Microbiology, University Hospital, SE 751 85 Uppsala, Sweden
    Int J Syst Evol Microbiol 53:1861-71. 2003
    ..In this study, rnpB was sequenced in 50 type strains and 29 additional strains of the genus Streptococcus. Putative secondary-structure models and possible interactions in RNase P RNA molecules are discussed...
  37. pmc Gene network and pathway analysis of bovine mammary tissue challenged with Streptococcus uberis reveals induction of cell proliferation and inhibition of PPARgamma signaling as potential mechanism for the negative relationships between immune response and
    Kasey M Moyes
    Department of Animal Sciences, University of Illinois, Urbana, 61801, USA
    BMC Genomics 10:542. 2009
    Information generated via microarrays might uncover interactions between the mammary gland and Streptococcus uberis (S. uberis) that could help identify control measures for the prevention and spread of S...
  38. pmc Genome sequence of a serotype M3 strain of group A Streptococcus: phage-encoded toxins, the high-virulence phenotype, and clone emergence
    Stephen B Beres
    Laboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT 59840, USA
    Proc Natl Acad Sci U S A 99:10078-83. 2002
    ..Serotype M3 strains of group A Streptococcus (GAS) are a common cause of severe invasive infections with unusually high rates of morbidity and mortality...
  39. pmc Molecular characterization of subject-specific oral microflora during initial colonization of enamel
    Patricia I Diaz
    Oral Infection and Immunity Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Building 30, Room 310, 30 Convent Dr, Bethesda, MD 20892 4350, USA
    Appl Environ Microbiol 72:2837-48. 2006
    ..In all subjects, however, 4-h and 8-h communities were dominated by Streptococcus spp. belonging to the Streptococcus oralis/Streptococcus mitis group...
  40. pmc Coaggregation-mediated interactions of streptococci and actinomyces detected in initial human dental plaque
    Robert J Palmer
    National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892 4350, USA
    J Bacteriol 185:3400-9. 2003
    ..In intrageneric coaggregation, streptococci such as Streptococcus gordonii DL1 recognize receptor polysaccharides (RPS) borne on other streptococci such as Streptococcus oralis ..
  41. pmc Salivaricin A2 and the novel lantibiotic salivaricin B are encoded at adjacent loci on a 190-kilobase transmissible megaplasmid in the oral probiotic strain Streptococcus salivarius K12
    Otto Hyink
    Department of Microbiology and Immunology, University of Otago, P O Box 56, Dunedin, New Zealand
    Appl Environ Microbiol 73:1107-13. 2007
    The commercial probiotic Streptococcus salivarius strain K12 is the prototype of those S...
  42. pmc The Streptococcus gordonii surface proteins GspB and Hsa mediate binding to sialylated carbohydrate epitopes on the platelet membrane glycoprotein Ibalpha
    Barbara A Bensing
    Division of Infectious Diseases, Veterans Affairs Medical Center, University of California, San Francisco 94121, USA
    Infect Immun 72:6528-37. 2004
    Platelet binding by Streptococcus gordonii strain M99 is dependent on expression of the cell wall-anchored glycoprotein GspB...
  43. pmc Natural competence in the genus Streptococcus: evidence that streptococci can change pherotype by interspecies recombinational exchanges
    L S Havarstein
    Department of Biotechnological Sciences, Agricultural University of Norway, As
    J Bacteriol 179:6589-94. 1997
    To map the incidence of natural competence in the genus Streptococcus, we used PCR to screen a number of streptococcal strains for the presence of the recently identified competence regulation operon, containing the comC, -D, and -E ..
  44. ncbi Invasive infection caused by Streptococcus dysgalactiae subsp. equisimilis: characteristics of strains and clinical features
    Takashi Takahashi
    Laboratory of Infectious Diseases, Graduate School of Infection Control Sciences, Kitasato University, Tokyo, Japan
    J Infect Chemother 17:1-10. 2011
    Among clinically isolated β-hemolytic streptococci, Streptococcus pyogenes and S. agalactiae were considered the main pathogens in humans until recently. In 1996, S. dysgalactiae subsp...
  45. pmc Whole-genome sequence of Streptococcus pseudopneumoniae isolate IS7493
    Dea Shahinas
    Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada
    J Bacteriol 193:6102-3. 2011
    b>Streptococcus pseudopneumoniae is a member of the viridans group streptococci (VGS) whose pathogenic significance is unclear. We announce the complete genome sequence of S. pseudopneumoniae IS7493...
  46. pmc Effect of recolonisation with "interfering" alpha streptococci on recurrences of acute and secretory otitis media in children: randomised placebo controlled trial
    K Roos
    Ear, Nose, and Throat Department, Lundby Hospital, 41717 Gothenburg, Sweden
    BMJ 322:210-2. 2001
    ....
  47. pmc Complete genome and transcriptomes of Streptococcus parasanguinis FW213: phylogenic relations and potential virulence mechanisms
    Jianing Geng
    Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, People s Republic of China
    PLoS ONE 7:e34769. 2012
    b>Streptococcus parasanguinis, a primary colonizer of the tooth surface, is also an opportunistic pathogen for subacute endocarditis...
  48. ncbi A preliminary study of the effect of probiotic Streptococcus salivarius K12 on oral malodour parameters
    J P Burton
    BLIS Technologies, Center for Innovation, University of Otago, Dunedin, New Zealand
    J Appl Microbiol 100:754-64. 2006
    To determine whether dosing with bacteriocin-producing Streptococcus salivarius following an antimicrobial mouthwash effects a change in oral malodour parameters and in the composition of the oral microbiota of subjects with halitosis.
  49. ncbi Effect of hydrolysable and condensed tannins on growth, morphology and metabolism of Streptococcus gallolyticus (S. caprinus) and Streptococcus bovis
    J D Brooker
    Animal Science Department, University of Adelaide, Roseworthy Campus, Roseworthy, SA 5371, Australia
    Microbiology 147:1025-33. 2001
    b>Streptococcus gallolyticus (S. caprinus) was resistant in vitro to at least 7% (w/v) tannic acid and 4% (w/v) acacia condensed tannin, levels 10-fold greater than those tolerated by S. bovis. Growth of S...
  50. ncbi Cow- and quarter-level risk factors for Streptococcus uberis and Staphylococcus aureus mastitis
    R N Zadoks
    Department of Farm Animal Health, Faculty of Veterinary Medicine, Utrecht University, The Netherlands
    J Dairy Sci 84:2649-63. 2001
    This study was designed to identify risk factors for intramammary infections with Streptococcus uberis and Staphylococcus aureus under field conditions...
  51. pmc Molecular detection, quantification, and isolation of Streptococcus gallolyticus bacteria colonizing colorectal tumors: inflammation-driven potential of carcinogenesis via IL-1, COX-2, and IL-8
    Ahmed S Abdulamir
    Institute of Bioscience, University Putra Malaysia, Selangor, Malaysia
    Mol Cancer 9:249. 2010
    Colorectal cancer (CRC) has long been associated with bacteremia and/or endocarditis by Streptococcus gallolyticus member bacteria (SGMB) but the direct colonization of SGMB along with its molecular carcinogenic role, if any, has not ..
  52. ncbi The effect of ingestion of milk supplemented with salivaricin A-producing Streptococcus salivarius on the bacteriocin-like inhibitory activity of streptococcal populations on the tongue
    Karen P Dierksen
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    FEMS Microbiol Ecol 59:584-91. 2007
    The colonization efficacies of salivaricin A (SalA)-producing Streptococcus salivarius strains 20P3 and 5 were compared when given in milk to 219 children, using either 2-day or 9-day dosing regimens...
  53. ncbi Cow-specific treatment of clinical mastitis: an economic approach
    W Steeneveld
    Department of Farm Animal Health, Faculty of Veterinary Medicine, Utrecht University, 3584 CL, Utrecht, The Netherlands
    J Dairy Sci 94:174-88. 2011
    ..These CM cases were caused by Streptococcus uberis and Streptococcus dysgalactiae (40%), Staphylococcus aureus (30%), or Escherichia coli (30%)...
  54. pmc Genome sequence of the bacteriocin-producing oral probiotic Streptococcus salivarius strain M18
    Nicholas C K Heng
    Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, P O Box 647, Dunedin 9054, New Zealand
    J Bacteriol 193:6402-3. 2011
    b>Streptococcus salivarius is a Gram-positive bacterial commensal and pioneer colonizer of the human oral cavity...
  55. pmc Involvement of the adc operon and manganese homeostasis in Streptococcus gordonii biofilm formation
    C Y Loo
    Department of Pediatric Dentistry, Goldman School of Dental Medicine, Boston University, Boston, Massachusetts 02118, USA
    J Bacteriol 185:2887-900. 2003
    Pioneer oral bacteria, including Streptococcus gordonii, initiate the formation of oral biofilms on tooth surfaces, which requires differential expression of genes that recognize unique environmental cues. An S...
  56. pmc Complete genome sequence of the African dairy isolate Streptococcus infantarius subsp. infantarius strain CJ18
    Christoph Jans
    Laboratory of Food Biotechnology, Institute of Food, Nutrition and Health, ETH Zurich, Zurich, Switzerland
    J Bacteriol 194:2105-6. 2012
    b>Streptococcus infantarius subsp. infantarius, a member of the Streptococcus bovis/Streptococcus equinus complex, is highly prevalent in artisanal dairy fermentations in Africa. Here the complete genome sequence of the dairy-adapted S...
  57. pmc Microbial and physiological characterization of weakly amylolytic but fast-growing lactic acid bacteria: a functional role in supporting microbial diversity in pozol, a Mexican fermented maize beverage
    G Díaz-Ruiz
    Departamento de Alimentos y Biotecnologia, Facultad de Quimica, UNAM, 04510 Mexico D F, Mexico
    Appl Environ Microbiol 69:4367-74. 2003
    ..Four different biotypes were distinguished via ribotyping; Streptococcus bovis strains were found to be predominant...
  58. ncbi Cross-sectional study of Streptococcus species in quarter milk samples of dairy cows in the canton of Bern, Switzerland
    M Guélat-Brechbuehl
    Clinic for Ruminants, Vetsuisse Faculty, University of Berne, Laengassstrasse 122, PB 8466, CH 3001, Berne, Switzerland
    Vet Rec 167:211-5. 2010
    ..A novel, simple and inexpensive laboratory method was used for the differentiation of Streptococcus species, and a risk factor analysis was carried out. The prevalence in the quarter milk samples was 0...
  59. ncbi Bacteremia due to beta-hemolytic Streptococcus group G: increasing incidence and clinical characteristics of patients
    Noa Sylvetsky
    Infectious Diseases Unit, Department of Internal Medicine, Shaare Zedek Medical Center, Jerusalem, Israel
    Am J Med 112:622-6. 2002
    To describe the epidemiology and clinical characteristics of patients diagnosed with Streptococcus group G bacteremia from 1990 to 1999 at a community teaching hospital in Israel.
  60. ncbi Increasing competence in the genus Streptococcus
    Leiv Sigve Havarstein
    Department of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, N 1432 As, Norway
    Mol Microbiol 78:541-4. 2010
    b>Streptococcus pneumoniae is one of the most important model organisms for studies on natural genetic transformation in bacteria...
  61. ncbi Gene content differences across strains of Streptococcus uberis identified using oligonucleotide microarray comparative genomic hybridization
    Ping Lang
    Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    Infect Genet Evol 9:179-88. 2009
    b>Streptococcus uberis is one of the principal causative agents of bovine mastitis. The organism is typically considered an environmental pathogen...
  62. ncbi Analysis of Streptococcus salivarius urease expression using continuous chemostat culture
    Y Y Chen
    Department of Dental Research, University of Rochester School of Medicine and Dentistry, NY 14642, USA
    FEMS Microbiol Lett 135:223-9. 1996
    ..Using continuous chemostat culture, urease activity in Streptococcus salivarius 57.I was examined as a function of growth pH, carbohydrate availability and growth rate...
  63. ncbi Isolation of Streptococcus canis from a Japanese raccoon dog with fibrinous pleuropneumonia
    T Murase
    Department of Veterinary Microbiology, Faculty of Agriculture, Tottori University, Tottori 680 8553, Japan
    Vet Rec 153:471-2. 2003
  64. pmc Delineation of Streptococcus dysgalactiae, its subspecies, and its clinical and phylogenetic relationship to Streptococcus pyogenes
    Anders Jensen
    Department of Biomedicine, Faculty of Health Sciences, Aarhus University, Aarhus, Denmark
    J Clin Microbiol 50:113-26. 2012
    The taxonomic status and structure of Streptococcus dysgalactiae have been the object of much confusion...
  65. pmc LytF, a novel competence-regulated murein hydrolase in the genus Streptococcus
    Kari Helene Berg
    Department of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, As, Norway
    J Bacteriol 194:627-35. 2012
    b>Streptococcus pneumoniae and probably most other members of the genus Streptococcus are competent for natural genetic transformation. During the competent state, S...
  66. ncbi Ciprofloxacin induces mutagenesis to antibiotic resistance independent of UmuC in Streptococcus uberis
    Emilia Varhimo
    University of Helsinki, Department of Basic Veterinary Sciences, PO Box 66, FIN 00014, Helsinki, Finland
    Environ Microbiol 10:2179-83. 2008
    b>Streptococcus uberis is an environmental bovine mastitis pathogen capable of UV-inducible SOS mutagenesis. Bacterial SOS systems can be induced by several chemicals including also antibiotics used in clinical practice...
  67. ncbi Characterization of fluoroquinolone-resistant beta-hemolytic Streptococcus spp. isolated in North America and Europe including the first report of fluoroquinolone-resistant Streptococcus dysgalactiae subspecies equisimilis: report from the SENTRY Antimicr
    Douglas J Biedenbach
    JMI Laboratories, North Liberty, IA 52317, USA
    Diagn Microbiol Infect Dis 55:119-27. 2006
    ..streptococci isolates with reduced fluoroquinolone susceptibility included the following Lancefield groups: A (Streptococcus pyogenes; 9 strains), B (Streptococcus agalactiae; 24 strains), C and G (14 strains)...
  68. pmc Complete genome sequence of the dairy isolate Streptococcus macedonicus ACA-DC 198
    Konstantinos Papadimitriou
    Laboratory of Dairy Research, Department of Food Science and Technology, Agricultural University of Athens, Athens, Greece
    J Bacteriol 194:1838-9. 2012
    The species Streptococcus macedonicus is associated with the food environment, especially with fermented dairy products. Here we present the complete 2...
  69. ncbi Characterization of a new protective antigen of Streptococcus canis
    Jiande Yang
    Department of Animal Science, Tianjin Agricultural University, Tianjin, 300384, China
    Vet Res Commun 34:413-21. 2010
    b>Streptococcus canis (S. canis), a lancefield group G streptococcus, is an opportunistic pathogen mainly found in dogs and cats. The study on pathogenesis and protective immune mechanism of S. canis is not clear...
  70. ncbi Three oligopeptide-binding proteins are involved in the oligopeptide transport of Streptococcus thermophilus
    Peggy Garault
    Unité de Biochimie et Structure des Protéines, Institut National de la Recherche Agronomique, 78352 Jouy en Josas Cedex, France
    J Biol Chem 277:32-9. 2002
    ..Our objective was to identify the functions essential to the optimum growth of Streptococcus thermophilus in milk. Using random insertional mutagenesis on a S...
  71. pmc The other group G Streptococcus: increased detection of Streptococcus canis ulcer infections in dog owners
    Maggie M Lam
    Department of Laboratory Medicine, University of Washington, USA
    J Clin Microbiol 45:2327-9. 2007
    beta-Hemolytic Lancefield group G Streptococcus dysgalactiae and Streptococcus canis cannot be distinguished when only Lancefield typing is performed. Phenotypic testing and 16S rRNA gene sequencing identified S...
  72. pmc Sequencing and comparative genome analysis of two pathogenic Streptococcus gallolyticus subspecies: genome plasticity, adaptation and virulence
    I Hsuan Lin
    Institute of Biomedical Informatics, National Yang Ming University, Taipei, Taiwan
    PLoS ONE 6:e20519. 2011
    b>Streptococcus gallolyticus infections in humans are often associated with bacteremia, infective endocarditis and colon cancers. The disease manifestations are different depending on the subspecies of S. gallolyticus causing the infection...
  73. ncbi Cotrimoxazole resistance of Streptococcus pneumoniae and commensal streptococci from Kampala, Uganda
    Maria Wilén
    Department of Medical Biochemistry and Microbiology, Uppsala University, Sweden
    Scand J Infect Dis 41:113-21. 2009
    ..There were no obvious differences between the mutation patterns in S. pneumoniae and commensal streptococci, suggesting that the chromosomal mutations have been spread by transformational interchanges of DNA among related organisms...
  74. ncbi SCM, a novel M-like protein from Streptococcus canis, binds (mini)-plasminogen with high affinity and facilitates bacterial transmigration
    Marcus Fulde
    Department of Medical Microbiology, Helmholtz Centre for Infection Research HZI, Braunschweig, Germany
    Biochem J 434:523-35. 2011
    b>Streptococcus canis is an important zoonotic pathogen capable of causing serious invasive diseases in domestic animals and humans. In the present paper we report the binding of human plasminogen to S...
  75. pmc Fate of free DNA and transformation of the oral bacterium Streptococcus gordonii DL1 by plasmid DNA in human saliva
    D K Mercer
    Rowett Research Institute, Bucksburn, Aberdeen, Great Britain
    Appl Environ Microbiol 65:6-10. 1999
    ..DNA that had been exposed to degradation by fresh saliva was capable of transforming naturally competent Streptococcus gordonii DL1 to erythromycin resistance, although transforming activity decreased rapidly, with a half-life of ..
  76. pmc Comparative efficacies of amoxicillin, clindamycin, and moxifloxacin in prevention of bacteremia following dental extractions
    P Diz Dios
    Department of Special Needs, School of Medicine and Dentistry, Santiago de Compostela University, Santiago de Compostela 15872, Spain
    Antimicrob Agents Chemother 50:2996-3002. 2006
    ..b>Streptococcus spp...
  77. ncbi Megaplasmids encode differing combinations of lantibiotics in Streptococcus salivarius
    Philip A Wescombe
    BLIS Technologies Ltd, Centre for Innovation, University of Otago, PO Box 56, Dunedin, 9001, New Zealand
    Antonie Van Leeuwenhoek 90:269-80. 2006
    b>Streptococcus salivarius strains commonly produce bacteriocins as putative anti-competitor or signalling molecules. Here we report that bacteriocin production by the oral probiotic strain S. salivarius K12 is encoded by a large (ca...
  78. pmc Comparative structural and molecular characterization of ribitol-5-phosphate-containing Streptococcus oralis coaggregation receptor polysaccharides
    Jinghua Yang
    Oral Infection and Immunity Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892 4352, USA
    J Bacteriol 191:1891-900. 2009
    The antigenically related coaggregation receptor polysaccharides (RPS) of Streptococcus oralis strains C104 and SK144 mediate recognition of these bacteria by other members of the dental plaque biofilm community...
  79. ncbi Streptococcus oligofermentans inhibits Streptococcus mutans through conversion of lactic acid into inhibitory H2O2: a possible counteroffensive strategy for interspecies competition
    Huichun Tong
    State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, China
    Mol Microbiol 63:872-80. 2007
    ..b>Streptococcus mutans, a major caries-causing pathogen, is a species which tends to interact competitively with other species ..
  80. ncbi Antimicrobial susceptibility of udder pathogens from cases of acute clinical mastitis in dairy cows
    Björn Bengtsson
    National Veterinary Institute, SE 751 89 Uppsala, Sweden
    Vet Microbiol 136:142-9. 2009
    ..in udder pathogens MICs in Staphylococcus aureus (n=211), coagulase-negative staphylococci (CNS) (n=56), Streptococcus uberis (n=113), Streptococcus dysgalactiae (n=152), Streptococcus agalactiae (n=6), Escherichia coli (n=163), ..
  81. pmc A shift from oral to blood pH is a stimulus for adaptive gene expression of Streptococcus gordonii CH1 and induces protection against oxidative stress and enhanced bacterial growth by expression of msrA
    A J Vriesema
    Department of Medical Microbiology, Academic Medical Center, 1105 AZ Amsterdam, The Netherlands
    Infect Immun 68:1061-8. 2000
    ..a recently developed promoter-screening vector, we isolated five promoter fragments from the genomic DNA of Streptococcus gordonii CH1 responding to this stimulus...
  82. ncbi The acid-tolerant microbiota associated with plaque from initial caries and healthy tooth surfaces
    G Svensater
    Department of Oral Biology, Faculty of Odontology, Malmo University, Malmo, Sweden
    Caries Res 37:395-403. 2003
    ..0, pH values regarded as critical for the demineralization of tooth enamel. At pH 5.0, members of the genus Streptococcus were the dominant group, but mutans streptococci accounted for less than half of the streptococcal viable ..
  83. pmc In vivo activation of the intracrine vitamin D pathway in innate immune cells and mammary tissue during a bacterial infection
    Corwin D Nelson
    Diseases and Immunology Research Unit, National Animal Disease Center, Agriculture Research Service, United States Department of Agriculture, Ames, Iowa, USA
    PLoS ONE 5:e15469. 2010
    ..1α-OHase gene expression in macrophages and mammary tissue during an in vivo bacterial infection with Streptococcus uberis...
  84. pmc Contribution of plasminogen activation towards the pathogenic potential of oral streptococci
    Andreas Itzek
    Department of Medical Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany
    PLoS ONE 5:e13826. 2010
    ..We conclude that the pathomechanism of plasminogen activation is conserved in oral streptococci that cause infections in human. This may contribute to their opportunistic pathogenic character that is unfurled in certain niches...
  85. ncbi Identification of early microbial colonizers in human dental biofilm
    J Li
    Department of Periodontology and Oral Biology, Goldman School of Dental Medicine, Boston University, Boston, MA 02118, USA
    J Appl Microbiol 97:1311-8. 2004
    ..To elucidate the first colonizers within in vivo dental biofilm and to establish potential population shifts that occur during the early phases of biofilm formation...
  86. ncbi Are horizontal transfers involved in the evolution of the Streptococcus thermophilus exopolysaccharide synthesis loci?
    F Bourgoin
    Laboratoire de Génétique et Microbiologie, UA INRA 952, Universite Henri Poincare Nancy I, Faculte des Sciences, BP 239, 54506, Vandoeuvre les Nancy, France
    Gene 233:151-61. 1999
    A 32.5kb variable locus of the Streptococcus thermophilus CNRZ368 chromosome, the eps locus, contains 25 ORF and seven insertion sequences (IS)...
  87. pmc A collagen-binding adhesin, Acb, and ten other putative MSCRAMM and pilus family proteins of Streptococcus gallolyticus subsp. gallolyticus (Streptococcus bovis Group, biotype I)
    Jouko Sillanpaa
    Division of Infectious Diseases, Department of Internal Medicine, University of Texas Medical School at Houston, Houston, Texas 77030, USA
    J Bacteriol 191:6643-53. 2009
    Members of the Streptococcus bovis group are important causes of endocarditis. However, factors associated with their pathogenicity, such as adhesins, remain uncharacterized...
  88. pmc Lysogenic transfer of group A Streptococcus superantigen gene among Streptococci
    Ivo Vojtek
    1Max F Perutz Laboratories, University of Vienna, Department of Microbiology and Immunobiology, Vienna, Austria
    J Infect Dis 197:225-34. 2008
    A group A Streptococcus (GAS) isolate, serotype M12, recovered from a patient with streptococcal toxic shock syndrome was analyzed for superantigen-carrying prophages, revealing phi149, which encodes superantigen SSA...
  89. pmc Six-month multicenter study on invasive infections due to Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis in Argentina
    Horacio A Lopardo
    Servicio de Microbiología Hospital de Pediatría Prof Dr Juan P Garrahan, Combate de los Pozos 1881 1245 Buenos Aires, Argentina
    J Clin Microbiol 43:802-7. 2005
    During a 6-month period, 95 invasive infections due to Streptococcus pyogenes and group C or group G Streptococcus dysgalactiae subsp. equisimilis were recorded from 40 centers of 16 cities in Argentina...
  90. ncbi Bovine mastitis in Finland 2001--prevalence, distribution of bacteria, and antimicrobial resistance
    A Pitkälä
    National Veterinary and Food Research Institute, EELA, PB 45, FIN 00581 Helsinki, Finland
    J Dairy Sci 87:2433-41. 2004
    ..1 and 32.0% for Staphylococcus aureus and coagulase-negative staphylococci, respectively). Streptococci isolated from mastitis were very susceptible to beta-lactam antibiotics, as also found in the previous survey in 1995...
  91. ncbi Differentiation of mutans streptococci by intact cell matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
    S Rupf
    Department of Conservative Dentistry and Periodontology, University of Leipzig, Germany
    Oral Microbiol Immunol 20:267-73. 2005
    ..spectrometry (MALDI-TOF-MS) (ICM) was applied to reference strains of five of the species of the mutans group (Streptococcus criceti, Streptococcus downei, Streptococcus mutans, Streptococcus ratti, Streptococcus sobrinus), nonmutans ..
  92. ncbi Molecular emm genotyping and antibiotic susceptibility of Streptococcus dysgalactiae subsp. equisimilis isolated from invasive and non-invasive infections
    Katsuhiko Sunaoshi
    Laboratory of Molecular Epidemiology for Infectious Agents, Graduate School of Infection Control Sciences, Kitasato University, Tokyo, Japan
    J Med Microbiol 59:82-8. 2010
    To analyse the characteristics of infections caused by Streptococcus dysgalactiae subsp. equisimilis, clinical isolates (n=145) were collected at 11 medical institutions between September 2003 and October 2005...
  93. ncbi Virulence profiling of Streptococcus dysgalactiae subspecies equisimilis isolated from infected humans reveals 2 distinct genetic lineages that do not segregate with their phenotypes or propensity to cause diseases
    Mark R Davies
    Bacterial Pathogenesis Laboratory, The Queensland Institute of Medical Research, Australia
    Clin Infect Dis 44:1442-54. 2007
    In spite of the emerging importance of Streptococcus dysgalactiae subspecies equisimilis (human group C streptococci [GCS] and group G streptococci [GGS]) in human health, its molecular makeup remains largely undefined...
  94. ncbi Assessment of GFP fluorescence in cells of Streptococcus gordonii under conditions of low pH and low oxygen concentration
    M C Hansen
    Molecular Microbial Ecology Group, Department of Microbiology, Technical University of Denmark, Building 301, DK-2800 Lyngby, Denmark
    Microbiology 147:1383-91. 2001
    ..by a synthetic constitutive lactococcal promoter was demonstrated in batch cultures and in biofilms of Streptococcus gordonii DL1...
  95. ncbi Partial recN gene sequencing: a new tool for identification and phylogeny within the genus Streptococcus
    Olga O Glazunova
    Laboratoire de Bacteriologie, Virologie, Hopital de la Timone, Marseille, Cedex 05, France
    Int J Syst Evol Microbiol 60:2140-8. 2010
    ..1 %) and gyrB (73.2 %). Phylogenetically derived trees revealed six statistically supported groups: Streptococcus salivarius, S. equinus, S. hyovaginalis/S. pluranimalium/S. thoraltensis, S. pyogenes, S. mutans and S. suis...
  96. ncbi Distribution of emm types and subtypes among noninvasive group A, C and G streptococcal isolates in western Norway
    Bård Reiakvam Kittang
    Department of Medicine, Haukeland University Hospital, University of Bergen, Bergen, Norway
    APMIS 116:457-64. 2008
    ..4% of the GCS and GGS isolates. The high proportion of skin isolates in the present study may indicate the existence of GAS, GCS and GGS strains with predominantly skin and soft tissue tropism in our community...
  97. pmc Cloning, expression, and characterization of the superantigen streptococcal pyrogenic exotoxin G from Streptococcus dysgalactiae
    Jizi Zhao
    Department of Infectious Diseases, Research Institute, International Medical Center of Japan, 1 21 1 Toyama, Shinjuku ku, Tokyo 162 8655, Japan
    Infect Immun 75:1721-9. 2007
    We identified seven novel variants of streptococcal pyrogenic exotoxin G (SPEGG), a superantigen, in Streptococcus dysgalactiae subsp. dysgalactiae or equisimilis isolates from clinical cases of infection in humans and animals...
  98. pmc The group I strain of Streptococcus mutans, UA140, produces both the lantibiotic mutacin I and a nonlantibiotic bacteriocin, mutacin IV
    F Qi
    Department of Oral Biology, School of Dentistry, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Appl Environ Microbiol 67:15-21. 2001
    Strains of Streptococcus mutans produce at least three mutacins, I, II, and III. Mutacin II is a member of subgroup AII in the lantibiotic family of bacteriocins, and mutacins I and III belong to subgroup AI in the lantibiotic family...
  99. ncbi Molecular markers for discriminating Streptococcus pyogenes and S. dysgalactiae subspecies equisimilis
    D J McMillan
    Bacterial Pathogenesis Laboratory, The Queensland Institute of Medical Research, 300, Herston Road, Brisbane, QLD 4006, Australia
    Eur J Clin Microbiol Infect Dis 29:585-9. 2010
    Given the increasing aetiological importance of Streptococcus dysgalactiae subspecies equisimilis in diseases which are primarily attributed to S...
  100. pmc Comprehensive study of strains previously designated Streptococcus bovis consecutively isolated from human blood cultures and emended description of Streptococcus gallolyticus and Streptococcus infantarius subsp. coli
    Marcella Beck
    Department of Medical Microbiology and Hygiene, Gärtner and Colleagues Laboratories, Ravensburg, Germany
    J Clin Microbiol 46:2966-72. 2008
    Modern taxonomy has delineated Streptococcus gallolyticus subsp. gallolyticus, S. gallolyticus subsp. pasteurianus, Streptococcus infantarius subsp. coli, and S. infantarius subsp...
  101. pmc An unstable competence-induced protein, CoiA, promotes processing of donor DNA after uptake during genetic transformation in Streptococcus pneumoniae
    Bhushan V Desai
    Laboratory for Molecular Biology, Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA
    J Bacteriol 188:5177-86. 2006
    Natural genetic transformation in Streptococcus pneumoniae entails transcriptional activation of at least two sets of genes...

Research Grants73

  1. Sutureless Laparoscopic Partial Nephrectomy Using Laser Tissue Welding: Preclinic
    Yasmin Wadia; Fiscal Year: 2013
    ..contaminated wounds of drug- resistant super bugs like Methicillin-Resistant Staphylococcus aureus (MRSA), Streptococcus pyogenes and Pseudomonas aeruginosa...
  2. Metabolic Engineering of Bacteria for Cancer Immunotherapy by Gamma Delta T Cells
    Craig T Morita; Fiscal Year: 2013
    ..Early in the 1900's, Coley successfully used a mix of heat-killed Streptococcus and Serratia bacteria to treat a variety of sarcomas and other cancers...
  3. Group A Streptococcus responses to oxidative stress
    Ioannis Gryllos; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Group A Streptococcus (GAS) employs multiple defense strategies to resist killing by reactive oxygen species (ROS) formed either by reduction of atmospheric oxygen or by phagocytes upon activation of ..
  4. Recombinant Attenuated Salmonella Vaccines for Humans
    Roy Curtiss; Fiscal Year: 2012
    ..Paratyphi A, hepatitis B virus (HBV), Streptococcus pneumoniae and Mycobacterium tuberculosis (Mtb) vary widely but may account for about 40 percent of the total ..
  5. The Electricidal Effect, a Novel Anti-Biofilm Strategy
    Robin Patel; Fiscal Year: 2013
    ..epidermidis, three isolates each of Escherichia coli and Enterococcus faecalis, and single isolates of each of Streptococcus mutans species group and Candida albicans also demonstrate an electricidal effect...
  6. MEMBRANES OF THE DENTAL PATHOGEN STREPTOCOCCUS MUTANS
    L Jeannine Brady; Fiscal Year: 2013
    ..in 25-30 billion dollars in annual health care costs in the US and is caused by the pathogenic bacterium Streptococcus mutans...
  7. Anti-Bacterial Innate Responses Enhance Paramyxovirus Replication
    Griffith D Parks; Fiscal Year: 2010
    ..In Aim 3, we will establish in vitro bacterial biofilms with nontypeable Haemophilus influenzae (NTHi) or with Streptococcus pneumoniae (pneumococcus) and determine the viral replication potential in immune and epithelial cells exposed ..
  8. Epidemiology and Etiology of Hospitalized Pneumonia in Children
    Krow Ampofo; Fiscal Year: 2010
    ..type b (Hib) vaccine and pneumococcal conjugate vaccine, and the emergence of non-vaccine serotypes of Streptococcus pneumioniae and highly virulent clones of methcillin resistant Staphylococcus aureus (MRSA)...
  9. Insights from Comparative Genomics for the Treatment of Pneumococcal Infections
    Natalia Luisa Hiller; Fiscal Year: 2011
    ..The focus of this proposal is on a clinically important subset of Streptococcus pneumoniae strains (the SP-1) that are pandemic and drug resistant. The aims are to: 1) develop an S...
  10. Therapeutics for Drug-Resistant Bacteria: Myxopyronins
    Richard H Ebright; Fiscal Year: 2013
    ..Myx exhibits potent antibacterial activity against Mycobacterium tuberculosis, Staphylococcus aureus, Streptococcus pneumoniae, Enterococcus faecalis, Enterobacter cloacae, and Clostridium difficile in culture...
  11. Insights from Comparative Genomics for the Treatment of Pneumococcal Infections
    Natalia Luisa Hiller; Fiscal Year: 2013
    ..The focus of this proposal is on a clinically important subset of Streptococcus pneumoniae strains (the SP-1) that are pandemic and drug resistant. The aims are to: 1) develop an S...
  12. Delineation of the molecular mechanisms underlying group A Streptococcus virulenc
    Paul Sumby; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The human bacterial pathogen group A Streptococcus (GAS) causes a broad spectrum of diseases, including pharyngitis, impetigo, and necrotizing fasciitis...
  13. Group B. Streptococci and Toll-like Receptors
    Douglas T Golenbock; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Group B streptococcus (GBS) is currently a leading single cause of neonatal sepsis and the third most frequent over all cause of bacterial meningitis in the United States...
  14. Development of a Novel PolC Inhibitor as a Gram-Positive Antibiotic
    THALE CROSS JARVIS; Fiscal Year: 2013
    ..Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP), Streptococcus pyogenes (Group A strep), vancomycin resistant enterococcus (VRE), Bacillus ..
  15. A common denominator of pathogenesis;a rare opportunity for novel therapeutic de
    DOUGLAS ALAN MITCHELL; Fiscal Year: 2011
    ..The best-known toxin in this family is the highly modified peptide, streptolysin S (SLS, produced by Streptococcus pyogenes). SLS production is required for the infective process, but not essential life processes...
  16. Transcriptional Control by the Global Regulator Spx
    PETER A ZUBER; Fiscal Year: 2013
    ..we discovered in the spore-forming bacterium, Bacillus subtilis, but is also found in Staphylococcus aureus, Streptococcus pneumoniae, Listeria monocytogenes, and Bacillus anthracis...
  17. Cellular functions of the essential PcrA helicase in Staphylococcus aureus
    Saleem A Khan; Fiscal Year: 2013
    ..protein present in Gram-positive bacteria, including important human pathogens such as Staphylococcus aureus, Streptococcus pneumonia, Clostridium perfringens, Listeria monocytogenes, Bacillus anthracis, etc. PcrA was discovered in S...
  18. Metal-dependent phosphohydrolase activity of CvfA from Streptococcus pyogenes
    GABRIELA CITLALLI PEREZ-ALVARADO; Fiscal Year: 2012
    ..phosphohydrolase domain and regulates the expression of glycolytic enzymes and virulence factors of Streptococcus pyogenes in response to low nutrient conditions...
  19. Contribution of the Streptococcus mutans cid and lrg Murein Hydrolase Regulator H
    KELLY CHRISTINE RICE; Fiscal Year: 2010
    b>Streptococcus mutans is the primary causative agent of dental caries, which remains the most common chronic disease among children and is untreated in up to 30% of adults over 35 yrs-old...
  20. Global Regulation of Gene expression in Streptococcus pneumoniae
    Bernard Weisblum; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Streptococcus pneumoniae is normally found as an inhabitant of the human nasopharynx that becomes pathogenic in response to environmental changes...
  21. GENETICS AND VIRULENCE OF PNEUMOCOCCAL CAPSULAR TYPES
    JANET L YOTHER; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Streptococcus pneumoniae is a major cause of morbidity and mortality worldwide, resulting in 1 to 2 million deaths annually. Serious infection and death result primarily from the ability of S...
  22. CT EIP Capacities ACA Grant
    TRACEY L WEEKS; Fiscal Year: 2011
    ..coli, Vibrio) as well as the active bacterial core surveillance project (Streptococcus pneumoniae, N. meningitidis, Listeria monocytogenes, Haemophilus influenzae). We are requesting funding for a ...
  23. Otitis media-associated pneumococcal genes
    Honggao Yan; Fiscal Year: 2013
    ..b>Streptococcus pneumoniae (the pneumococcus) is the most common cause of childhood OM...
  24. Cardiac dysfunction in StrepTSS: interplay of SLO and MMPs
    Dennis L Stevens; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Group A streptococcus (GAS) causes a particularly severe form of septic shock termed Streptococcal Toxic Shock Syndrome (StrepTSS) and mortalities range from 30-70% despite modern medical practices...
  25. Eukaryotic-type STK/STP-mediated modulation of enterococcal pathogenesis
    Vijay Pancholi; Fiscal Year: 2010
    ..Based on the findings of group A Streptococcus (GAS) ESTK and ESTP that we recently characterized, we hypothesize that enterococcal efSTK and efSTP have ..
  26. Novel biofilm polymicrobial infection-resistant implants for otologic application
    Paul Stoodley; Fiscal Year: 2010
    ..new materials and to injection mold TTs, 2) to confirm our in vitro studies with Haemophilus influenzae and Streptococcus pneumoniae, and quantify synergy and monitor for the development of resistant strains, 3) to assess ..
  27. Regulation of NETosis in antibacterial lung defense
    EILEEN REMOLD-O'DONNELL; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Pneumonias resulting from failure to eradicate bacterial (Streptococcus pneumonia, Haemophilus influenza, Staphylococcus aureus, Pseudomonas aeruginosa) and viral (rhinovirus, influenza virus) ..
  28. Development of transformed lactobacilli as a microbicide
    Richard B Markham; Fiscal Year: 2010
    ..VHH using three different mouse model systems and two different bacterial strains, one of which, Streptococcus gordonii, is selected specifically for the purpose of demonstrating proof of principle in mouse model systems ..
  29. Respiratory Panel Flow-Strip: a Point-of-Care Molecular Diagnostic Test
    CHRISTOPHER GERARD COONEY; Fiscal Year: 2012
    ..human rhinovirus A/B/C, human bocavirus 1/2/3/4, human parainfluenza virus 1/2/3/4, Haemophilus influenzae, Streptococcus pneumoniae, Mycoplasma pneumoniae, Chlamydophila pneumoniae, Legionella pneumophila, and Bordetella pertussis...
  30. Mechanism of PsrP mediated adhesion
    Carlos J Orihuela; Fiscal Year: 2013
    ..psrP-secY2A2 is a 37-kb pathogenicity island whose presence has been positively correlated with the ability of Streptococcus pneumoniae to cause human disease...
  31. Dissecting the Function and Regulation of Stress-Induced SUMOylation
    ROBERT CHARLES AUGUSTINE; Fiscal Year: 2013
    ..In addition, several pathogenic bacteria (Listeria monocytogenes, Streptococcus pneumoniae) and viruses (human adenovirus, influenza virus) alter SIS, and this is important for bypassing ..
  32. Expression of clp genes in Streptococcus mutans
    Indranil Biswas; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Streptococcus mutans is considered as the major etiological agent in dental caries. S. mutans is also an important agent of infective endocarditis...
  33. DETERMINANTS OF H. INFLUENZAE VIRULENCE IN OTITIS MEDIA
    Lauren O Bakaletz; Fiscal Year: 2013
    ..Since the recent licensure of a 7-valent vaccine directed against Streptococcus pneumoniae, the relative proportion of cases of OM due to our studied microorganism (nontypeable Haemophilus ..
  34. GAS Switch from Colonizing Bacterium to Invasive Pathogen
    Victor Nizet; Fiscal Year: 2012
    ..Project Narrative Group A Streptococcus (GAS) is a bacteria that is a leading cause of infections in humans of all ages, from simple [unreadable]strep ..
  35. Genetics and Genomics of the yidC paralogs in Streptococcus mutans
    SARA MARIE RASER PALMER; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Streptococcus mutans is the primary etiological agent of dental caries (cavities), but the bacterium also causes endocarditis and is strongly associated with cardiovascular disease and stroke...
  36. Genome Sequencer FLX Instrument
    ANNE VIRGINIA KANE; Fiscal Year: 2010
    ..any other unanticipated genome rearrangements will be used in studies of the infectious agents Vibrio cholera, Streptococcus pneumoniae and Legionella pneumophila...
  37. The effect of inter-species interactions on the virulence of Streptococcus mutans
    Bing yan Wang; Fiscal Year: 2009
    Project summary: Streptococcus mutans is the primary cariogen that produces several virulence factors. The long-term goal of the proposed studies is to characterize specific interactions of S...
  38. Inhibition of lung defense by air pollutant particulates
    LISA KATHLEEN RYAN; Fiscal Year: 2010
    ..the effect on mice inhaling vanadium and then infected with airway pathogens that cause pneumonia, such as Streptococcus zooepidemicus and Staphylococcus aureus...
  39. New composite material design based on studies of tooth-composite and microbial i
    J Paul Santerre; Fiscal Year: 2013
    ..Objective: To establish methods for reproducibly measuring gene expression of Streptococcus mutans and Lactobacillus casei in situ after formation of biofilms on resin composite, along the resin-dentin ..
  40. Investigating SloR virulence gene metalloregulation in S. mutans.
    Grace A Spatafora; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Streptococcus mutans-induced caries formation continues to be a major problem in developed and developing nations which, according to the World Health Organization, impacts 60-90% of children world-..
  41. Targeting Pneumococcal Virulence Factors in Otitis Media
    Honggao Yan; Fiscal Year: 2012
    ..b>Streptococcus pneumoniae not only is the major bacterial cause of otitis media but also causes additional life-threatening ..
  42. The Abeta protein of Alzheimer's Disease is an antimicrobial peptide
    Robert D Moir; Fiscal Year: 2013
    ..clinically important microorganisms, including Candida albicans, Escherichia coli, Staphylococcus epidermidis, Streptococcus pneumoniae, Staphylococcus aureus, Listeria monocytogenes, Enterococcus faecalis, and Streptococcus agalactiae...
  43. The Role of PcpA in the Mechanism of Virulence and Protective Immunity.
    MELISSA MARIE WALKER; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Streptococcus pneumoniae is still a major cause of morbidity and mortality around the world and its most common clonotypes are resistant to most first line antibiotics...
  44. REGULATION OF LIPID METABOLISM IN BACTERIA
    Charles O Rock; Fiscal Year: 2013
    ..fatty acid and phospholipid synthesis in two important human pathogens: Staphylococcus aureus and Streptococcus pneumoniae...
  45. Studies of YlxM of Streptococcus mutans, a newly identified component of the Sign
    MATTHEW LAWRENCE WILLIAMS; Fiscal Year: 2013
    ..b>Streptococcus mutans is a cariogenic oral pathogen whose virulence is determined in large part by its membrane composition...
  46. Functional Amyloid Formation in Streptococcus mutans
    L Jeannine Brady; Fiscal Year: 2013
    ..caries is the most common infectious disease in the world caused in large part by the Gram-positive bacterium Streptococcus mutans...
  47. Age-associated Toll-like receptor dysfunction in the lungs
    Carlos J Orihuela; Fiscal Year: 2010
    ..TLR-1, -2, and -4 protein levels in the lungs of aged mice versus young mice;2) aged mice infected with Streptococcus pneumoniae develop fulminate pneumonia and die within 36 hours whereas young mice remain relatively healthy;3) ..
  48. Investigating SloR virulence gene metalloregulation in S. mutans.
    Grace Spatafora; Fiscal Year: 2009
    Abstract: Streptococcus mutans-induced caries formation continues to be a major problem in developed and developing nations which, according to the World Health Organization, impacts 60-90% of children world-wide (123)...
  49. Antimicrobial Phototherapy of Antibiotic Resistant Chronic Sinusitis
    MERRILL ABRAHAM BIEL; Fiscal Year: 2011
    ..studies have reported the presence of antibiotic resistant Pseudomonas aerugenosa, Hemophilus influenza, Streptococcus pneumoniae and Staphylococcus aureus biofilms in the sinuses of cure resistant CRS...
  50. Role of the Spx Regulator in Streptococcus mutans
    JOSE A LEMOS; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Data from clinical and basic research have implicated Streptococcus mutans as the primary microbial etiologic agent of dental caries, one of the most common infectious diseases afflicting humans...
  51. Role of influenza-induced prothrombosis in Streptococcus pyogenes superinfections
    Michael S Chaussee; Fiscal Year: 2012
    ..During the recent flu pandemic, Streptococcus pyogenes caused about 1/3 of the known cases of superinfection...
  52. Cytokine-stimulated systemic defenses during pneumococcal pneumonia
    Joseph P Mizgerd; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Streptococcus pneumoniae (pneumococcus) is the most common cause of community-acquired pneumonia...
  53. Coordinate regulation of competence and pneumocin production in S. pneumoniae
    SUZANNE RACHEL DAWID; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Streptococcus pneumoniae (pneumococcus) is an important human pathogen and the most common cause of bacterial meningitis, pneumonia and otitis media...
  54. Impact of the Nasal Microbiome on S. aureus Colonization and Infection
    Mary Bessesen; Fiscal Year: 2013
    ..aureus for the anterior nares niche have focused on individual species, e.g. Staphylococcus epidermidis, Streptococcus pneumoniae, Corynebacterium spp., isolated from culture...
  55. Pneumococcal capsule and host innate immunity
    Moon H Nahm; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Streptococcus pneumoniae is a Gram-positive bacterium that can express more than 90 different capsule types (serotypes) and is often carried as a commensal in the human nasopharynx (NPX), but can ..
  56. Bacteriophage Control of DNA Repair in Streptococcus Pyogenes
    WILLIAM MICHAEL MCSHAN; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The group A streptococcus (GAS;Streptococcus pyogenes) is a major bacterial pathogen of humans, globally causing over 700,000,000 infections and more than 500,000 deaths each year...
  57. Rapid, automated, detection of viral and bacterial pathogens causing meningitis
    Andrew Hemmert; Fiscal Year: 2013
    ..monocytogenes, Mycoplasma pneumoniae, N. meningitidis, P. aeruginosa, Staphylococci species, S. aureus, Streptococcus species, S. agalactiae, S. pneumoniae, S...
  58. Modulation of Autoimmune Diabetes by N-acetyl-D-glucosamine Specific B cells
    BRIAN L DIZON; Fiscal Year: 2010
    ..This study will attempt to determine how a common infectious organism, Group A Streptococcus, can alter an individual's propensity to develop type I diabetes (T1D)...
  59. Synthetic saccharides to study immunological properties of Streptococcus pneumoni
    Alexei V Demchenko; Fiscal Year: 2010
    ..The bacteria Streptococcus pneumoniae (SPn) have become one of the most frequent causes of pneumonia, bacteremia, and meningitis in the ..
  60. Novel aryl-rhodanine inhibitors of Streptococcus mutans biofilms
    TIMOTHY J OPPERMAN; Fiscal Year: 2012
    ..The mutans streptococcal group, represented by Streptococcus mutans and S. sobrinis, are the major causative agents of dental caries...
  61. Role of Macrophage Migration Inhibitory Factor (MIF) in Pneumococcal Pathogenesis
    Rituparna Das; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Despite the use of antibiotics and vaccines, Streptococcus pneumoniae (pneumococcus) remains a leading cause of community acquired pneumonia and mortality...
  62. Immune Responses in Otitis Prone Children
    Michael E Pichichero; Fiscal Year: 2013
    ..among otitis prone (OP) children to infections caused by nontypeable Haemophilus influenzae (NTHi) and Streptococcus pneumoniae (Spn)...
  63. MECHANISMS INVOLVED IN FLAVIN-LINKED OXYGEN METABOLISM
    Al Claiborne; Fiscal Year: 2005
    ..of this group: (1) NADH oxidase (Nox; 2NADH + O2 to 2NAD+ + 2H2O) from the severe human pathogen Streptococcus pyogenes, (2) NADH peroxidase (Npx; NADH + H2O2 - to NAD+ + 2H2O) from Enterococcus faecalis, and (3) alpha-..
  64. Developing acid-activated antimicrobial peptides to control dental caries
    Maxwell Anderson; Fiscal Year: 2009
    ..microbial species together with a limited number of acid- producing (cariogenic) bacteria such as Streptococcus mutans and Lactobacillus species...
  65. Development of targeted photodynamic therapy for treatment of dental caries
    Randal Eckert; Fiscal Year: 2010
    ..together with a limited number of pathogenic bacteria, including the major etiological agent of dental caries, Streptococcus mutans, which ferments dietary sugars to produce enamel-damaging organic acids. The eradication of S...
  66. Molecular bssis of mef-mediated antibiotic resistance in Streptococcus pneumoniae
    David S Stephens; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): The basis for the emergence of mefE-associated macrolide resistance in Streptococcus pneumoniae is a genetic element, mega (macrolide efflux genetic assembly)...
  67. REGULATION OF IMMUNE RESPONSE IN THE ORAL CAVITY
    Suzanne Michalek; Fiscal Year: 2003
    ..g., teeth. Secretory IgA antibodies in saliva are important in protection against oral diseases, including Streptococcus mutans-induced dental caries, and are induced following stimulation of the common mucosal immune system (CMIS)...
  68. CLONING AND PURIFICATION OF A VEILLONELLA ADHESIN
    Christopher Hughes; Fiscal Year: 1993
    ..Veillonella, Prevotella, Actinomyces and Streptococcus utilize similar mechanisms to adhere to common streptococcal coaggregation partners...
  69. Scaffolds for Synthesis of Probes Directed Against Class II HMG-CoA Reductases
    Cynthia Stauffacher; Fiscal Year: 2007
    ..It has recently been shown that a number of common human pathogens, including Enterococcus faecalis, Streptococcus pneumoniae and Staphylococcus aureus are dependent on enzymes in the mevalonate pathway for biosynthesis of ..
  70. MtaR-regulated virulence in Streptococcus agalactiae
    Daniel Shelver; Fiscal Year: 2009
    DESCRIPTION (provided by applicant). Streptococcus agalactiae (group B Streptococcus;GBS) is a leading cause of invasive infections such as pneumonia, sepsis, and meningitis in neonates...
  71. 3rd ASM Conference on Cell-Cell Communication in Bacteria
    WILLIAM FUQUA; Fiscal Year: 2007
    ..might communicate with each other via chemical signals, specifically in regulating genetic competence in Streptococcus pneumoniae and in controlling bioluminescence in Vibrio fischeri, respectively...
  72. Duration of Intrapartum Antibiotic Prophylaxis for Group B Streptococcus
    Jessica L Illuzzi; Fiscal Year: 2010
    Vertical transmission of group B streptococcus (GBS) from colonized mothers to their newborns can be attenuated by intrapartum antibiotic prophylaxis...
  73. Heme Acquisition in Group A Streptococcus
    Benfang Lei; Fiscal Year: 2005
    Hemolytic Streptococcus pyogenes, commonly referred as Group A Streptococcus (GAS), is an important human pathogen causing pharyngitis, cellulitis, scarlet fever, necrotizing fasciitis, toxic shock syndrome, acute rheumatic fever, ..