peptostreptococcus

Summary

Summary: A genus of gram-positive, anaerobic, coccoid bacteria that is part of the normal flora of humans. Its organisms are opportunistic pathogens causing bacteremias and soft tissue infections.

Top Publications

  1. ncbi Structure, specificity, and mode of interaction for bacterial albumin-binding modules
    Maria U Johansson
    Department of Biophysical Chemistry, Lund University, P O Box 124, SE 221 00 Lund, Sweden
    J Biol Chem 277:8114-20. 2002
  2. ncbi Identification of interdomain sequences promoting the intronless evolution of a bacterial protein family
    M de Château
    Department of Cell and Molecular Biology, Lund University, Sweden Maarten de
    Proc Natl Acad Sci U S A 93:8490-5. 1996
  3. ncbi Complex between Peptostreptococcus magnus protein L and a human antibody reveals structural convergence in the interaction modes of Fab binding proteins
    M Graille
    , , Centre d'Etudes Saclay, F-91191, Gif-sur-Yvette, France
    Structure 9:679-87. 2001
  4. ncbi Whole-body autoradiography reveals that the Peptostreptococcus magnus immunoglobulin-binding domains of protein L preferentially target B lymphocytes in the spleen and lymph nodes in vivo
    David Smith
    Section for Immunology, Department of Cell and Molecular Biology, Lund University, Lund, Sweden
    Cell Microbiol 6:609-23. 2004
  5. ncbi Comparative analysis of the four rRNA operons in Finegoldia magna ATCC29328
    Kozo Todo
    Department of Microbiology, Wakayama Medical University, Wakayama, Japan
    Syst Appl Microbiol 27:18-26. 2004
  6. ncbi Apparent culture-negative prosthetic valve endocarditis caused by Peptostreptococcus magnus
    E R van der Vorm
    Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Clin Microbiol 38:4640-2. 2000
  7. ncbi Bacterial artificial chromosome library of Finegoldia magna ATCC 29328 for genetic mapping and comparative genomics
    Takatsugu Goto
    Department of Microbiology, Wakayama Medical University, Kimiidera, Wakayama, Japan
    Microbiol Immunol 47:1005-16. 2003
  8. ncbi Endocarditis caused by Finegoldia magna (formerly Peptostreptococcus magnus): diagnosis depends on the blood culture system used
    Stefano Bassetti
    Division of Infectious Diseases, University Hospital Basel, Petersgraben 4, CH -4031 Basel, Switzerland. sbassetti @uhbs.ch
    Diagn Microbiol Infect Dis 47:359-60. 2003
  9. ncbi Physical and genetic map of the Finegoldia magna (formerly Peptostreptococcus magnus) ATCC 29328 genome
    Kozo Todo
    Department of Microbiology, Wakayama Medical University, 811-1 Kimiidera, 641-0012, Japan
    FEMS Microbiol Lett 210:33-7. 2002
  10. ncbi Structures of the B1 domain of protein L from Peptostreptococcus magnus with a tyrosine to tryptophan substitution
    D E Kim
    Division of Basic Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA
    Acta Crystallogr D Biol Crystallogr 57:480-7. 2001

Research Grants

  1. Oral microbial associations in HIV+subjects
    BRUCE PASTER; Fiscal Year: 2003
  2. Natural antimicrobials against bacterial vaginosis
    Michael Chikindas; Fiscal Year: 2006
  3. Role of Bacterial Vaginosis in Preterm Delivery
    ROBIN ROSS; Fiscal Year: 2003
  4. B Cell Superantigen Immune Complex Tissue Inflammation
    Arnold Levinson; Fiscal Year: 2007
  5. Three Periodontal Therapies in Current & Non-Smokers
    Anne Haffajee; Fiscal Year: 2007
  6. Molecular Mechanism of F. Nucleatum Virulence
    Yiping Han; Fiscal Year: 2006
  7. Streptococcus mutans and Dental Caries in Native American Children
    David Drake; Fiscal Year: 2007
  8. Quantification of Host Markers in GCF Using CBIB
    Ricardo Teles; Fiscal Year: 2007
  9. Photodynamic Therapy for Endodontic Disinfection
    NIKOLAOS SOUKOS; Fiscal Year: 2007
  10. Biologic Basis of Refractory Periodontal Disease
    BRUCE PASTER; Fiscal Year: 2006

Detail Information

Publications185 found, 100 shown here

  1. ncbi Structure, specificity, and mode of interaction for bacterial albumin-binding modules
    Maria U Johansson
    Department of Biophysical Chemistry, Lund University, P O Box 124, SE 221 00 Lund, Sweden
    J Biol Chem 277:8114-20. 2002
    ..it folds into a left handed three-helix bundle similar to the albumin binding domain of protein PAB from Peptostreptococcus magnus...
  2. ncbi Identification of interdomain sequences promoting the intronless evolution of a bacterial protein family
    M de Château
    Department of Cell and Molecular Biology, Lund University, Sweden Maarten de
    Proc Natl Acad Sci U S A 93:8490-5. 1996
    ..of genes, duplication of functional domains, and as shown for protein PAB of the anaerobic bacterial species Peptostreptococcus magnus, by the shuffling of an albumin-binding protein module from group C and G streptococci...
  3. ncbi Complex between Peptostreptococcus magnus protein L and a human antibody reveals structural convergence in the interaction modes of Fab binding proteins
    M Graille
    , , Centre d'Etudes Saclay, F-91191, Gif-sur-Yvette, France
    Structure 9:679-87. 2001
    BACKGROUND: Peptostreptococcus magnus protein L (PpL) is a multidomain, bacterial surface protein whose presence correlates with virulence...
  4. ncbi Whole-body autoradiography reveals that the Peptostreptococcus magnus immunoglobulin-binding domains of protein L preferentially target B lymphocytes in the spleen and lymph nodes in vivo
    David Smith
    Section for Immunology, Department of Cell and Molecular Biology, Lund University, Lund, Sweden
    Cell Microbiol 6:609-23. 2004
    Protein L is an immunoglobulin (Ig)-binding protein produced by the Gram-positive bacterium Peptostreptococcus magnus that interacts with the variable region of Ig kappa light chains...
  5. ncbi Comparative analysis of the four rRNA operons in Finegoldia magna ATCC29328
    Kozo Todo
    Department of Microbiology, Wakayama Medical University, Wakayama, Japan
    Syst Appl Microbiol 27:18-26. 2004
    There are four rRNA operons rrnA, rrnB, rrnC and rrnD on the genome of Finegoldia magna (formerly Peptostreptococcus magnus) ATCC29328, which, in contrast to those of Clostridia, are dispersed around the chromosome...
  6. ncbi Apparent culture-negative prosthetic valve endocarditis caused by Peptostreptococcus magnus
    E R van der Vorm
    Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Clin Microbiol 38:4640-2. 2000
    In two patients with prosthetic valve endocarditis due to Peptostreptococcus magnus, blood cultures in the BacT/Alert and BACTEC 9240 systems were signal negative...
  7. ncbi Bacterial artificial chromosome library of Finegoldia magna ATCC 29328 for genetic mapping and comparative genomics
    Takatsugu Goto
    Department of Microbiology, Wakayama Medical University, Kimiidera, Wakayama, Japan
    Microbiol Immunol 47:1005-16. 2003
    ..The BAC library constructed here will be useful for the whole genome sequencing project and other postgenomic applications...
  8. ncbi Endocarditis caused by Finegoldia magna (formerly Peptostreptococcus magnus): diagnosis depends on the blood culture system used
    Stefano Bassetti
    Division of Infectious Diseases, University Hospital Basel, Petersgraben 4, CH -4031 Basel, Switzerland. sbassetti @uhbs.ch
    Diagn Microbiol Infect Dis 47:359-60. 2003
    We present a patient with prosthetic valve endocarditis caused by Finegoldia magna (formerly Peptostreptococcus magnus). Blood cultures in the BacT/ALERT and BACTEC 9240 system were negative...
  9. ncbi Physical and genetic map of the Finegoldia magna (formerly Peptostreptococcus magnus) ATCC 29328 genome
    Kozo Todo
    Department of Microbiology, Wakayama Medical University, 811-1 Kimiidera, 641-0012, Japan
    FEMS Microbiol Lett 210:33-7. 2002
    A physical and genetic map of Finegoldia magna (formerly Peptostreptococcus magnus) ATCC 29328 chromosome was constructed...
  10. ncbi Structures of the B1 domain of protein L from Peptostreptococcus magnus with a tyrosine to tryptophan substitution
    D E Kim
    Division of Basic Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA
    Acta Crystallogr D Biol Crystallogr 57:480-7. 2001
    ..These high-resolution structures of the tryptophan-containing variant provide a reference frame for the analysis of thermodynamic and kinetic data derived from a series of mutational studies of the protein L B1 domain...
  11. ncbi Nitroimidazole resistance genes (nimB) in anaerobic Gram-positive cocci (previously Peptostreptococcus spp.)
    Maria M Theron
    Department of Medical Microbiology G4, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa
    J Antimicrob Chemother 54:240-2. 2004
    ..To investigate metronidazole resistance and the prevalence of nitroimidazole (nim) genes in clinically isolated anaerobic Gram-positive cocci...
  12. ncbi The family Coriobacteriaceae: reclassification of Eubacterium exiguum (Poco et al. 1996) and Peptostreptococcus heliotrinreducens (Lanigan 1976) as Slackia exigua gen. nov., comb. nov. and Slackia heliotrinireducens gen. nov., comb. nov., and Eubacterium
    W G Wade
    Department of Oral Medicine and Pathology, Guy s Hospital, King s College London, UK
    Int J Syst Bacteriol 49:595-600. 1999
    16S rRNA gene sequences were determined for Eubacterium exiguum and Peptostreptococcus heliotrinreducens...
  13. ncbi Multicenter survey of the changing in vitro antimicrobial susceptibilities of clinical isolates of Bacteroides fragilis group, Prevotella, Fusobacterium, Porphyromonas, and Peptostreptococcus species
    K E Aldridge
    Department of Medicine (Infectious Diseases, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
    Antimicrob Agents Chemother 45:1238-43. 2001
    ..antimicrobial agents were highly active against isolates of Prevotella, Fusobacterium, Porphyromonas, and Peptostreptococcus. These data further establish and confirm that clinically important anaerobes can vary widely in their ..
  14. ncbi Rapid identification of Gram-positive anaerobic coccal species originally classified in the genus Peptostreptococcus by multiplex PCR assays using genus- and species-specific primers
    Yuli Song
    Research Service, VA Medical Center West Los Angeles, LA, USA yulis
    Microbiology 149:1719-27. 2003
    ..PCR assay for identifying 14 Gram-positive anaerobic cocci (GPAC) species originally classified in the genus Peptostreptococcus (Anaerococcus hydrogenalis, Anaerococcus lactolyticus, Anaerococcus octavius, Anaerococcus prevotii, ..
  15. ncbi [A comparative study of various evaluation methods of the antibiotic sensitivity of strict anaerobic bacteria of the subgingival flora]
    A Kamagate
    , ,
    Odontostomatol Trop 24:9-12. 2001
    ..are: Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, Campylobacter rectus, Peptostreptococcus micros. Antibiotics used are: ampicilline, amoxicilline, tetracycline, erythromycine, metronidazole...
  16. ncbi Bacteriology and antimicrobial susceptibility of gram-positive cocci isolated from pus specimens of orofacial odontogenic infections
    T Kuriyama
    Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, Ishikawa, Japan
    Oral Microbiol Immunol 17:132-5. 2002
    ..Streptococcus constellatus and Peptostreptococcus micros were frequent isolates from all types of infection examined...
  17. ncbi [Early diagnosis of bacterial brain abscesses: interest of diffusion-weighted MRI]
    O Detante
    Service de Neurologie, Hopital Henri Mondor, Creteil
    Rev Neurol (Paris) 159:421-4. 2003
    ..36- 0.49 x 10(-3) mm2/s). So, this new MRI technique provides an available and rapid element in the brain abscess diagnosis which often remains a complex clinical and radiological diagnosis...
  18. ncbi Phenolic antibacterials from Piper betle in the prevention of halitosis
    Niranjan Ramji
    The Procter and Gamble Company, Health Care Research Center, 8700 Mason Montgomery Road, Mason, OH 45040, USA
    J Ethnopharmacol 83:149-52. 2002
    ..The biological studies with APC indicated that the potential to reduce methylmercaptan and hydrogen sulfide was mainly due to the anti-microbial activity as established using dynamic in vitro models...
  19. ncbi Mutans streptococci in subgingival plaque of treated and untreated patients with periodontitis
    W A van der Reijden
    Sections of Clinical Periodontal Microbiology and Oral Microbiology, Department of Oral Biology, Academic Centre for Dentistry Amsterdam, The Netherlands
    J Clin Periodontol 28:686-91. 2001
    ..005) and 2.51% in patients after scaling and root planing (p=0.041). CONCLUSIONS: The subgingival area is a microbial habitat for mutans streptococci that may be of importance in the development of root caries in periodontitis patients...
  20. ncbi Smoking affects the subgingival microflora in periodontitis
    A J van Winkelhoff
    Department of Oral Biology, Section of Clinical Periodontal Microbiology, Academic Centre for Dentistry, Amsterdam, The Netherlands
    J Periodontol 72:666-71. 2001
    ..of U-S were a higher prevalence of Prevotella intermedia/nigrescens and higher mean levels of Peptostreptococcus micros (Pm) and Fusobacterium nucleatum (Fn)...
  21. ncbi Subgingival microflora in Turkish patients with periodontitis
    Basak Dogan
    Department of Periodontology, Faculty of Dentistry, University of Gazi, Ankara, Turkey
    J Periodontol 74:803-14. 2003
    ..No information exists on periodontitis-associated subgingival microbiota from Turkey. We determined the occurrence, interspecies relationships, and clonal characteristics for a group of periodontal bacteria in a Turkish study population...
  22. ncbi Antimicrobial susceptibility of major pathogens of orofacial odontogenic infections to 11 beta-lactam antibiotics
    T Kuriyama
    Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan
    Oral Microbiol Immunol 17:285-9. 2002
    ..The antimicrobial susceptibilities of viridans streptococci (n = 47), Peptostreptococcus (n = 67), Porphyromonas (n = 18), Fusobacterium (n = 57), black-pigmented Prevotella (n = 59) and non-..
  23. ncbi Amoxicillin plus metronidazole in the treatment of adult periodontitis patients. A double-blind placebo-controlled study
    E G Winkel
    Department of Periodontology, Academic Centre for Dentistry, Amsterdam, The Netherlands
    J Clin Periodontol 28:296-305. 2001
    ..gingivalis, B. forsythus and Peptostreptococcus micros. 4 subgroups were created on the basis of the initial microbiological status for P...
  24. ncbi Mice lacking monocyte chemoattractant protein 1 have enhanced susceptibility to an interstitial polymicrobial infection due to impaired monocyte recruitment
    P Chae
    Department of Endodontics, Boston University School of Dental Medicine, Massachusetts 02118, USA
    Infect Immun 70:3164-9. 2002
    ....
  25. ncbi Actinobacillus actinomycetemcomitans proportion of subgingival bacterial flora in relation to its clonal type
    Laura Lakio
    Institute of Dentistry, University of Helsinki, Finland
    Eur J Oral Sci 110:212-7. 2002
    ..actinomycetemcomitans may preferentially occur as low proportions, suggesting their controlled growth. Conversely, some serotype b clones may have a competitive advantage in subgingival flora...
  26. ncbi [Bacteriologic investigation of periodontal infections]
    Z Barna
    ,
    Fogorv Sz 94:97-100. 2001
    ..The knowledge of microbial composition of the periodontal flora could help to diagnose the different forms of periodontitis. It can also assist the indication of the most appropriate antibiotic therapy...
  27. ncbi Porphyromonas gingivalis, Bacteroides forsythus and other putative periodontal pathogens in subjects with and without periodontal destruction
    A J van Winkelhoff
    Department of Dental Basic Sciences, Section Oral Microbiology, Academic Centre for Dentistry Amsterdam, The Netherlands
    J Clin Periodontol 29:1023-8. 2002
    ..gingivalis, Prevotella intermedia, Bacteroides forsythus, Fusobacterium nucleatum and Peptostreptococcus micros were significantly more often prevalent in patients than in controls...
  28. ncbi Antibacterial properties of electron beam-sterilized Gutta-Percha cones
    T Attin
    Department of Operative Dentistry and Periodontology, , Germany
    J Endod 27:172-4. 2001
    ..with -one aerobic bacterium (Bacillus subtilis) and five oral anaerobic bacteria (Fusobacterium nucleatum, Peptostreptococcus micros, Porphyromonas gingivalis, Propionibacterium acnes, and Veillonella parvula)...
  29. ncbi The microflora recovered from the outer-surfaces of the Frialit-2 implanto-prosthetic connector
    Rainer Buchmann
    Department of Periodontology and Oral Biology, Goldman School of Dental Medicine, Boston University, USA
    Clin Oral Implants Res 14:28-34. 2003
    ..5%), Porphyromonas gingivalis (81.3%), and Peptostreptococcus micros (68.8%) with enhanced proportions for P. gingivalis (11.4%) and P. micros (11.4%)...
  30. ncbi Suppurative parotitis caused by anaerobic bacteria in newborns
    Itzhak Brook
    Department of Pediatrics, Georgetown University School of Medicine, Washington, DC, USA
    Pediatr Infect Dis J 21:81-2. 2002
    ..b>Peptostreptococcus intermedius and Prevotella melaninogenica were isolated from one child and Prevotella intermedia from the ..
  31. ncbi Aggressive periodontitis associated with Fanconi's anemia. A case report
    H Nowzari
    University of Southern California School of Dentistry, Los Angeles, USA
    J Periodontol 72:1601-6. 2001
    ..1% of total isolates), FusobActerium species (7.9%), Campylobacter species (2.2%), Peptostreptococcus micros (3.4%), and Candida albicans (0.3%)...
  32. ncbi Maternal periodontitis and prematurity. Part II: Maternal infection and fetal exposure
    P N Madianos
    Center for Oral and Systemic Diseases, Departments of Periodontology and Dental Ecology, University of North Carolina at Chapel Hill, School of Dentistry, Chapel Hill, NC, USA
    Ann Periodontol 6:175-82. 2001
    ..with periodontitis, conventionally termed "Orange" (Campylobacter rectus, Fusobacterium nucleatum, Peptostreptococcus micros, Prevotella nigrescens, and Prevotella intermedia) and "Red" (Porphyromonas gingivalis, ..
  33. ncbi Supragingival and subgingival microbiota of adult patients with Down's syndrome. Changes after periodontal treatment
    D Sakellari
    Department of Preventive Dentistry, Periodontology and Implant Biology, Dental School, Aristotle University of Thessaloniki, 54006, Greece
    Oral Microbiol Immunol 16:376-82. 2001
    ..Inadequate oral hygiene as performed by these patients probably affected supragingival, and consequently subgingival, plaque composition...
  34. ncbi An immunohistological study of the localization of bacteria invading root pulpal walls of teeth with periapical lesions
    Takashi Matsuo
    Department of Conservative Dentistry, University of Tokushima School of Dentistry, Kuramoto, Japan
    J Endod 29:194-200. 2003
    ..Fusobacterium nucleatum, Eubacterium alactolyticum, E. nodatum, Lactobacillus casei, and Peptostreptococcus micros were abundant. Even in the canal-enlarged group, invasion of bacteria was observed in 65% of teeth...
  35. ncbi Subgingival microbiota of indigenous Indians of Central America
    S A Dowsett
    Indiana University School of Dentistry, IN, USA
    J Clin Periodontol 29:159-67. 2002
    ..At the subject level, Actinomyces naeslundii and Peptostreptococcus micros were significantly more prevalent in periodontally-healthy subjects...
  36. ncbi [Clinical and microbiological study of adult periodontal disease]
    A Nogueira Moreira
    , , Universidad Nacional de Buenos Aires, Marcelo T. de Alvear 2124, 1222 Buenos Aires, Argentina
    Rev Argent Microbiol 33:133-40. 2001
    ..gingivalis (23%), Actinobacillus actinomycetemcomitans (23%), Fusobacterium nucleatum (10%) and Peptostreptococcus sp. (31%). The aerobic gram-positive microflora was predominant in healthy sites...
  37. ncbi Acute bacterial suppurative parotitis: microbiology and management
    Itzhak Brook
    Georgetown University School of Medicine, Washington, DC, USA
    J Craniofac Surg 14:37-40. 2003
    ..Fusobacterium spp., and Peptostreptococcus spp. Streptococcus spp. (including S...
  38. ncbi Viable bacteria in root dentinal tubules of teeth with apical periodontitis
    L B Peters
    Department of Cariology, Endodontology, and Pedodontology, Academic Center for Dentistry Amsterdam, The Netherlands
    J Endod 27:76-81. 2001
    ..It seems clear that, in more than half of the infected roots, bacteria are present in the deep dentin close to the cementum and that anaerobic culturing of dentin is more sensitive than histology to detect these bacteria...
  39. ncbi The clinical relevance of microbiologic testing: a comparative analysis of microbiologic samples secured from the same sites and cultured in two independent laboratories
    J R Mellado
    Department of Periodontology, Temple University School of Dentistry, Philadelphia, USA
    Int J Periodontics Restorative Dent 21:232-9. 2001
    ....
  40. ncbi [Extrinsic ureteral obstruction secondary to inflammatory gynecologic pathology]
    Guillermo Conde Santos
    Servicio y Cátedra de Urología, Hospital del Mar, Universidad Autonoma de Barcelona, Barcelona, Espana
    Arch Esp Urol 56:181-5. 2003
    ..To present two cases of extrinsic ureteral obstruction secondary to gynaecological inflammatory diseases, and to perform a bibliographic review...
  41. ncbi Microbiology and management of chronic suppurative otitis media in children
    I Brook
    J Trop Pediatr 49:196-9. 2003
  42. ncbi Distribution of periodontal pathogens in Korean aggressive periodontitis
    Jung-Wook Lee
    Department of Periodontology, College of Dentistry, Yonsei University, Seoul, Korea
    J Periodontol 74:1329-35. 2003
    ..4% for Fusobacterium sp., 85.9% for Micromonas micros (formerly Peptostreptococcus micros), 96.8% for Porphyromonas gingivalis, 78.8% for Prevotella intermedia, and 96.8% for Treponema sp...
  43. ncbi Microbiology of intracranial abscesses and their associated sinusitis
    Itzhak Brook
    Department of Pediatrics, Georgetown University School of Medicine, Washington, DC, USA
    Arch Otolaryngol Head Neck Surg 131:1017-9. 2005
    ..To evaluate the organisms recovered from infected sinuses and associated intracranial abscesses (IAs)...
  44. ncbi Molecular analysis of bacteria in asymptomatic and symptomatic endodontic infections
    M Sakamoto
    Microbe Division Japan Collection of Microorganisms, RIKEN BioResource Center, Wako, Saitama, Japan
    Oral Microbiol Immunol 21:112-22. 2006
    ..commonly detected taxa were Fusobacterium nucleatum (including terminal restriction fragment types 1 and 2), Peptostreptococcus micros/Peptostreptococcus sp...
  45. ncbi The role of anaerobic bacteria in mediastinitis
    Itzhak Brook
    Georgetown University School of Medicine, Washington, DC 20016, USA
    Drugs 66:315-20. 2006
    ..The predominant anaerobic isolates include Bacteroides spp., Peptostreptococcus spp., pigmented Prevotella and Porphyromonas spp. and Fusobacterium spp...
  46. ncbi Influence of residual bacteria on periapical tissue healing after chemomechanical treatment and root filling of experimentally infected monkey teeth
    Lars Fabricius
    Department of Oral Microbiology, , Sweden
    Eur J Oral Sci 114:278-85. 2006
    ..The present study demonstrates the importance of obtaining a bacteria-free root canal system before permanent root filling in order to achieve optimal healing conditions for the periapical tissues...
  47. ncbi Aerobic and anaerobic microbiology of necrotizing fasciitis in children
    I Brook
    Department of Pediatrics, Georgetown University School of Medicine, Washington, USA
    Pediatr Dermatol 13:281-4. 1996
    ..The predominant isolates were Peptostreptococcus spp. (6 isolates, including 3 Peptostreptococcus magnus). S...
  48. ncbi Microbiology and antibiotic sensitivities of head and neck space infections of odontogenic origin
    Anthony J Rega
    Department of Oral and Maxillofacial Surgery, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103-2400, USA
    J Oral Maxillofac Surg 64:1377-80. 2006
    ..3%) isolated. The most common bacteria isolated were Viridans streptococci, Provetella, Staphylococci, and Peptostreptococcus. Culture and sensitivities were reviewed on 101 patients...
  49. ncbi Coaggregation interactions between oral and endodontic Enterococcus faecalis and bacterial species isolated from persistent apical periodontitis
    Erika M Johnson
    Department of Cariology, Restorative Sciences and Endodontics, The University of Michigan, School of Dentistry, Ann Arbor, Michigan 48109-1078, USA
    J Endod 32:946-50. 2006
    ..clinical isolates and species previously shown to survive and induce apical periodontitis in monkeys: Peptostreptococcus anaerobius, Prevotella oralis, Fusobacterium nucleatum, and Streptococcus anginosus...
  50. ncbi Photodynamic therapy for endodontic disinfection
    Nikolaos S Soukos
    Applied Molecular Photomedicine Laboratory, The Forsyth Institute, Boston, Massachusetts 02115 3799, USA
    J Endod 32:979-84. 2006
    ..We conclude that PDT may be developed as an adjunctive procedure to kill residual bacteria in the root canal system after standard endodontic treatment...
  51. ncbi Human serum activity of telithromycin, azithromycin and amoxicillin/clavulanate against common aerobic and anaerobic respiratory pathogens
    Gary E Stein
    Department of Medicine, B320 Life Sciences Building, Michigan State University, East Lansing, MI 48824, USA
    Int J Antimicrob Agents 29:39-43. 2007
    ..rapid and prolonged inhibitory activity (>or=12h) against each of the anaerobes studied (Finegoldia [Peptostreptococcus] magna Peptostreptococcus micros, Prevotella bivia, and Prevotella melaninogenica)...
  52. ncbi Comparison of subgingival bacterial sampling with oral lavage for detection and quantification of periodontal pathogens by real-time polymerase chain reaction
    Khalil Boutaga
    Department of Oral Microbiology, Academic Center for Dentistry Amsterdam, University of Amsterdam and Vrije University, Amsterdam, The Netherlands
    J Periodontol 78:79-86. 2007
    ....
  53. ncbi Antimicrobial susceptibility of 800 anaerobic isolates from patients with dentoalveolar infection to 13 oral antibiotics
    T Kuriyama
    Department of Oral and Maxillofacial Surgery, Kanazawa University Hospital, Kanazawa, Japan
    Oral Microbiol Immunol 22:285-8. 2007
    ....
  54. ncbi Periodontal microbiota in patients with coronary artery disease measured by real-time polymerase chain reaction: a case-control study
    Claudia Nonnenmacher
    Institute of Medical Microbiology and Hygiene, Philipps University Marburg, Marburg, Germany
    J Periodontol 78:1724-30. 2007
    ..This case-control study aimed at studying the relationship between periodontal disease and coronary artery disease (CAD) based on clinical and periodontal microbiologic parameters...
  55. ncbi Evaluation of the microbiota of primary endodontic infections using checkerboard DNA-DNA hybridization
    L Sassone
    Proclin Department, Rio de Janeiro State University, RJ, Brazil
    Oral Microbiol Immunol 22:390-7. 2007
    ..The aim of this study was to evaluate the composition of the microbiota of primary endodontic infections in 111 selected cases of single-rooted teeth with necrotic pulp...
  56. ncbi SMAP29 congeners demonstrate activity against oral bacteria and reduced toxicity against oral keratinocytes
    P L Weistroffer
    Department of Periodontics, College of Dentistry, University of Iowa, Iowa City, IA 52242, USA
    Oral Microbiol Immunol 23:89-95. 2008
    ..The purpose of this study was to evaluate the antimicrobial properties and cytotoxicity of SMAP29, SMAP28, and three congeners (SMAP18A, SMAP18D, and SMAP14A)...
  57. ncbi Antibacterial action of photoactivated disinfection {PAD} used on endodontic bacteria in planktonic suspension and in artificial and human root canals
    Jill A Williams
    Department of Biomaterials in Relation to Dentistry, Medical Science Building, Queen Mary University of London, Mile End Road, London E1 4NS, UK
    J Dent 34:363-71. 2006
    ..Methods: Four bacteria, Fusobacterium nucleatum,Peptostreptococcus micros, Prevotella intermedia and Streptococcus intermedius, were tested in suspension...
  58. ncbi [The occurrence of microorganisms in intraoral abscesses]
    Anna Kedzia

    Med Dosw Mikrobiol 57:209-15. 2005
    ..The predominant anaerobes were from genus Prevotella, Bacteroides, Fusobacterium and Peptostreptococcus. Among aerobic bacteria, the most frequent were gram-positive cocci...
  59. ncbi Antibiotic susceptibility of bacterial isolates in gingivitis and periodontitis
    S Saini
    Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India
    Indian J Dent Res 14:95-100. 2003
    ..Metronidazole was found to be the best for the anaerobes while the aerobes and facultative anaerobes showed good susceptibility to cefazolin and cefotaxime...
  60. ncbi Bacteremia following surgical dental extraction with an emphasis on anaerobic strains
    A Rajasuo
    Department of Oral and Maxillofacial Diseases, Mikkeli Central Hospital, Porrassalmenkatu 35 37, FIN 50100 Mikkeli, Finland
    J Dent Res 83:170-4. 2004
    ..9 +/- 2.6 species isolated per subject. Most prevalent were the anaerobes Prevotella, Eubacterium, and Peptostreptococcus sp. and the aerobes viridans-group streptococci and Streptococcus milleri group...
  61. ncbi Characteristics of anaerobes from skin specimens
    S Higaki
    Department of Dermatology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Sugitani, Toyama, Japan
    Drugs Exp Clin Res 29:153-5. 2003
    Anaerobes isolated from skin specimens from 1999 to 2001 were examined. The most common type was Peptostreptococcus spp., especially P. magnus and P. assaccharolyticus and Bacteroides fragilis. Dominance was seen for P. magnus, P...
  62. ncbi Antibiotic resistance profile of the subgingival microbiota following systemic or local tetracycline therapy
    Rosa Maria J Rodrigues
    , Universidade Federal do Rio de Janerio, Rio de Janeiro, Brazil
    J Clin Periodontol 31:420-7. 2004
    ..The predominant tetracycline-resistant species included Streptococcus spp., Veillonela parvula, Peptostreptococcus micros, Prevotella intermedia, Gemella morbillorum and Actinobacillus actinomycetemcomitans (Aa)...
  63. ncbi Apical periodontitis development and bacterial response to endodontic treatment. Experimental root canal infections in monkeys with selected bacterial strains
    Ake J R Möller
    Department of Oral Microbiology, Sahlgrenska Academy at Goteborg University, Gothenburg, Sweden
    Eur J Oral Sci 112:207-15. 2004
    ..were inoculated with a combination of four bacterial strains belonging to species Streptococcus milleri, Peptostreptococcus anaerobius, Prevotella oralis, and Fusobacterium nucleatum...
  64. ncbi Subgingival microbiota of chilean patients with chronic periodontitis
    Nestor J Lopez
    Department of Conservative Dentistry, Section of Periodontics, Faculty of Dentistry, University of Chile, Santiago, Chile
    J Periodontol 75:717-25. 2004
    ..A study was undertaken to determine the characteristics of the subgingival microbiota of chronic periodontitis in Chileans residing in Santiago...
  65. ncbi Periimplantitis
    Maria Angeles Sanchez-Garcés
    Facultad de Odontologia, Universidad de Barcelona
    Med Oral Patol Oral Cir Bucal 9:69-74; 63-9. 2004
    ....
  66. ncbi Parotid salivary S-IgA antibodies during experimental gingivitis in smokers and non-smokers
    M A Lie
    Department of Periodontology, Academic Center for Dentistry Amsterdam (ACTA, The Netherlands
    J Periodontal Res 37:86-92. 2002
    ..rectus, Fusobacterium nucleatum, Porphyromonas gingivalis, Prevotella intermedia, Prevotella nigrescens, Peptostreptococcus micros, Streptococcus gordonii and Streptococcus mutans were determined in the samples by means of ELISA...
  67. ncbi [Pharmacokinetic/pharmacodynamic analysis of antibiotic therapy in dentistry and stomatology]
    Arantxazu Isla
    , Facultad de Farmacia, , Vitoria-Gasteiz, Spain
    Enferm Infecc Microbiol Clin 23:116-21. 2005
    ..Clinical trials are required to confirm that this methodology is useful in these pathologic processes...
  68. ncbi Periodontal pathogens: a quantitative comparison of anaerobic culture and real-time PCR
    Khalil Boutaga
    Department of Oral Microbiology, Academic Center for Dentistry Amsterdam, VU University Medical Center Amsterdam, Amsterdam, The Netherlands
    FEMS Immunol Med Microbiol 45:191-9. 2005
    ..the 16s rRNA genes of Actinobacillus actinomycetemcomitans, Prevotella intermedia, Tannerella forsythensis, Peptostreptococcus micros and Fusobacterium spp. were developed...
  69. ncbi Prevalence of periodontopathic bacteria in aggressive periodontitis patients in a Chilean population
    Marta Gajardo
    Area of Microbiology, Faculty of Dentistry, University of Chile, Santiago, Chile
    J Periodontol 76:289-94. 2005
    ..The aim of the present study was to determine the prevalence of eight periodontopathic bacteria in Chilean patients with AgP...
  70. ncbi Antimicrobial profiles of periodontal pathogens isolated from periodontitis patients in The Netherlands and Spain
    A J van Winkelhoff
    Department of Oral Microbiology, Academic Centre for Dentistry Amsterdam, Amsterdam, The Netherlands
    J Clin Periodontol 32:893-8. 2005
    ..The aim of the present study was to compare antimicrobial susceptibility profiles of five periodontal bacteria isolated from periodontitis patients in Spain and in The Netherlands...
  71. ncbi Photodynamic therapy as an adjunct to non-surgical periodontal treatment: a randomized, controlled clinical trial
    Nicos Christodoulides
    Department of Periodontology, Radboud University Medical Center, Philips van Leydenlaan 25, Nijmegen, The Netherlands
    J Periodontol 79:1638-44. 2008
    ..The aim of this study was to evaluate the clinical and microbiologic effects of the adjunctive use of PDT to non-surgical periodontal treatment...
  72. ncbi Association of early onset periodontitis microbiota with aspartate aminotransferase activity in gingival crevicular fluid
    J J Kamma
    Department of Periodontology, School of Dental Medicine, University of Athens, Greece
    J Clin Periodontol 28:1096-105. 2001
    ....
  73. ncbi Photodynamic therapy as adjunct to non-surgical periodontal treatment in patients on periodontal maintenance: a randomized controlled clinical trial
    Panos Chondros
    Department of Periodontology, Radboud University Medical Center, Nijmegen, The Netherlands
    Lasers Med Sci 24:681-8. 2009
    ..g.), Prevotella intermedia (P.i.), Tannerella forsythensis (T.f.), Treponema denticola (T.d.), Peptostreptococcus micros (P.m.), Fusobacterium nucleatum (F.n.), Campylobacter rectus (C.r.), Eubacterium nodatum (E.n...
  74. ncbi [Identification of anaerobic bacteria isolated from various clinical specimens and determination of antibiotic susceptibilities]
    Metin Dogan
    Karaman Devlet Hastanesi, Mikrobiyoloji Laboratuvari, Karaman
    Mikrobiyol Bul 44:211-9. 2010
    ..necrophorum/nucleatum (n = 1), Prevotella intermedia/disiens (n = 1), Peptococcus niger (n = 2), Peptostreptococcus spp. (n = 5), and Lactobacillus acidophilus/lenseii (n = 1)...
  75. ncbi In vitro activity of gemifloxacin (SB 265805) against anaerobes
    E J Goldstein
    R M Alden Research Laboratory, Santa Monica University of California at Los Angeles Medical Center, Santa Monica, California 90404, USA
    Antimicrob Agents Chemother 43:2231-5. 1999
    ..25 and 0.5; for Fusobacterium varium (13), 0.5 and 1; for Fusobacterium spp. (12), 1 and 2; for Peptostreptococcus anaerobius (13), 0.06 and 0.06; for Peptostreptococcus asaccharolyticus (13), 0.125 and 0...
  76. ncbi Microbiological profile of early onset/aggressive periodontitis patients
    J J Kamma
    Laboratory of Periodontology, Department of Periodontology, University of Athens, Greece
    Oral Microbiol Immunol 19:314-21. 2004
    ....
  77. ncbi Susceptibility of anaerobic bacteria in Auckland: 1991-1996
    K P Shore
    Microbiology Laboratory, Auckland Hospital
    N Z Med J 112:424-6. 1999
    ..To determine the antimicrobial susceptibility of local anaerobic bacteria...
  78. ncbi Profile of subgingival microbiota in children with mixed dentition
    J J Kamma
    Department of Periodontology, School of Dental Medicine, University of Athens, Greece
    Oral Microbiol Immunol 15:103-11. 2000
    ..gingivalis, Prevotella loescheii, Campylobacter gracilis, Bacteroides forsythus, Campylobacter concisus, Peptostreptococcus micros and Selenomonas sputigena, albeit less frequently detected, were present in the microbiota of these ..
  79. ncbi Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems
    Chia Ying Liu
    Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Antimicrob Agents Chemother 52:3161-8. 2008
    ..6% and 0% for Prevotella species (n = 16), 15% and 0% for Clostridium species (n = 28), and 0% and 0% for Peptostreptococcus species (n = 32). The rates of susceptibility to moxifloxacin were 90% for B. fragilis isolates, 87% for B...
  80. ncbi In vitro activities of faropenem against 579 strains of anaerobic bacteria
    Hannah M Wexler
    Department of Medicine, Immunology and Molecular Genetics, University of California Los Angeles School of Medicine, Los Angeles, California 90024, USA
    Antimicrob Agents Chemother 46:3669-75. 2002
    ..Faropenem had MICs of 8 and 16 micro g/ml, respectively, for two strains of Peptostreptococcus anaerobius (MICs of imipenem were 2 micro g/ml)...
  81. ncbi Human beta-defensins 2 and 3 demonstrate strain-selective activity against oral microorganisms
    Sophie Joly
    Dows Institute for Dental Research, University of Iowa, Iowa City, Iowa 52242, USA
    J Clin Microbiol 42:1024-9. 2004
    ..of oral organisms (Actinobacillus actinomycetemcomitans, Fusobacterium nucleatum, Porphyromonas gingivalis, Peptostreptococcus micros, Actinomyces naeslundii, Actinomyces israelii, Streptococcus sanguis, Streptococcus mutans, Candida ..
  82. ncbi Assessment of the microbiota in root canals of human primary teeth by checkerboard DNA-DNA hybridization
    Denise Belucio Ruviére
    Department of Pediatric Clinics, Preventive and Community Dentistry, School of Dentistry of Ribeirao Preto, University of Sao Paulo, Ribeirãvo Preto, Sao Paulo, Brazil
    J Dent Child (Chic) 74:118-23. 2007
    ..The purpose of this study was to evaluate in vivo the prevalence of microorganisms in root canals of human primary teeth, by checkerboard DNA-DNA hybridization...
  83. ncbi Antibacterial activity of medicinal plant extracts against periodontopathic bacteria
    L Iauk
    Department of Microbiological Sciences, University of Catania, Via Androne 81, 95124 Catania, Italy
    Phytother Res 17:599-604. 2003
    ..Fusobacterium nucleatum, Capnocytophaga gingivalis, Veilonella parvula, Eikenella corrodens, Peptostreptococcus micros and Actinomyces odontolyticus. The methanol extracts of H. virginiana and A...
  84. ncbi Bacterial vaginosis a "broad overview"
    A González Pedraza Avilés
    C S C Dr José Castro Villagrana, Departamento de Medicina Familiar, Facultad de Medicina, UNAM, Instituto de Servicios de Salud del Distrito Federal, Mexico D F
    Rev Latinoam Microbiol 41:25-34. 1999
    ..vaginalis, anaerobic Gram-negative rods such as Prevotella species, Peptostreptococcus species, Mycoplasma hominis, Ureaplasma urealyticum, and often Mobiluncus species...
  85. ncbi Initial antimicrobial effect of controlled-release doxycycline in subgingival sites
    M G Jorgensen
    University of Southern California School of Dentistry, Los Angeles, California 90089 0641, USA
    J Periodontal Res 39:315-9. 2004
    ..To determine the ability of a 10% doxycycline hyclate controlled-release polymer (Atridox) to suppress periodontopathic bacteria when placed subgingivally following scaling and root planing (Sc/Rp)...
  86. ncbi Activities of gemifloxacin (SB 265805, LB20304) compared to those of other oral antimicrobial agents against unusual anaerobes
    E J Goldstein
    The R M Alden Research Laboratory, Santa Monica UCLA Medical Center, Santa Monica, California 90404, USA
    Antimicrob Agents Chemother 43:2726-30. 1999
    ..Peptostreptococci (Peptostreptococcus asaccharolyticus, Peptostreptococcus magnus, Peptostreptococcus micros, and Peptostreptococcus prevotii) and ..
  87. ncbi Normal ocular features, conjunctival microflora and intraocular pressure in the Canadian beaver (Castor canadensis)
    C L Cullen
    Department of Companion Animals, Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown, Prince Edward Island, C1A 4P3 Canada
    Vet Ophthalmol 6:279-84. 2003
    ..The aim of the study was to assess the ocular features, normal conjunctival bacterial and fungal flora, and intraocular pressure (IOP) in the Canadian beaver (Castor canadensis)...
  88. ncbi Profile of subgingival microbiota in children with primary dentition
    J J Kamma
    Department of Periodontology, School of Dental Medicine, University of Athens, Greece
    J Periodontal Res 35:33-41. 2000
    ..Forty-one different microbial species were isolated. Gemella morbillorum and Peptostreptococcus magnus were statistically significantly more frequently detected in incisors while P...
  89. ncbi Tobacco smoking and periodontal microflora in a Saudi Arabian population
    Suzan Natto
    Institute of Odontology, Karolinska Institutet, Stockholm, Sweden
    J Clin Periodontol 32:549-55. 2005
    ..To explore the subgingival periodontal microflora in a Saudi Arabian population with a special focus on its relationship with various smoking habits...
  90. ncbi Phylogenetic analysis of bacterial and archaeal species in symptomatic and asymptomatic endodontic infections
    M M Vickerman
    Department of Periodontics and Endodontics, University at Buffalo School of Dentistry, Buffalo, NY, USA
    J Med Microbiol 56:110-8. 2007
    ..primers designed to detect Prevotella intermedia, Porphyromonas gingivalis, Porphyromonas endodontalis, Peptostreptococcus micros, Enterococcus sp., Streptococcus sp...
  91. ncbi Surveillance of susceptibility patterns in 1297 European and US anaerobic and capnophilic isolates to co-amoxiclav and five other antimicrobial agents
    Laura M Koeth
    Laboratory Specialists, Inc, Cleveland, OH, USA
    J Antimicrob Chemother 53:1039-44. 2004
    ..125/0.25 for Fusobacterium nucleatum, 0.5/1 for Eikenella corrodens, 0.25/8 for Peptostreptococcus anaerobius, </=0.125/0.5 for Micromonas (Peptostreptococcus) micros, </=0.25/0...
  92. ncbi Preterm birth: associations with genital and possibly oral microflora
    G B Hill
    Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC, USA
    Ann Periodontol 3:222-32. 1998
    ..in which Gardnerella vaginalis; anaerobic species primarily among Prevotella, Porphyromonas, Bacteroides, Peptostreptococcus, and Mobiluncus; Mycoplasma hominis; and Ureaplasma urealyticum become predominant in vaginal secretions...
  93. ncbi Rapid identification of non-sporing anaerobes using nuclear magnetic resonance spectroscopy and an identification strategy
    S Menon
    Department of Microbiology, Grant Medical College and Sir J J Hospital, Mumbai 400 008, Maharashatra, India
    Indian J Med Microbiol 25:330-5. 2007
    ....
  94. ncbi Degradation of host protease inhibitors and activation of plasminogen by proteolytic enzymes from Porphyromonas gingivalis and Treponema denticola
    D Grenier
    Faculte de Medecine Dentaire, Universite Laval, Sainte Foy, Quebec, Canada
    Microbiology 142:955-61. 1996
    ..gingivalis, T. denticola, Prevotella intermedia, Prevotella nigrescens and Capnocytophaga spp. Peptostreptococcus micros and Propionibacterium acnes had only some degradative activity on selected inhibitors, whereas three ..
  95. ncbi Vaginal microflora associated with bacterial vaginosis in nonpregnant women: reliability of sialidase detection
    J Smayevsky
    Laboratorio de Microbiologia, Centro de Educación Médica e Investigaciones Clínicas Dr Norberto Quirno CEMIC, Buenos Aires, Argentina
    Infect Dis Obstet Gynecol 9:17-22. 2001
    ....
  96. ncbi The consequences of suppression of anaerobic bacteria
    D E Fry
    Department of Surgery, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA
    Surg Infect (Larchmt) 1:49-56. 2000
    Anaerobic bacteria such as Bacteroides fragilis, Peptostreptococcus species, and Fusobacterium species, when accompanied by aerobic bacteria or in the presence of dead tissue, can cause severe infections...
  97. ncbi Microbiology and management of joint and bone infections due to anaerobic bacteria
    Itzhak Brook
    Department of Pediatrics, Georgetown University, School of Medicine, 3900 Reservoir Road NW, Washington, DC 20007, USA
    J Orthop Sci 13:160-9. 2008
    ..To describes the microbiology, diagnosis, and management of septic arthritis and osteomyelitis due to anaerobic bacteria...
  98. ncbi In vitro activities of the new semisynthetic glycopeptide telavancin (TD-6424), vancomycin, daptomycin, linezolid, and four comparator agents against anaerobic gram-positive species and Corynebacterium spp
    Ellie J C Goldstein
    R M Alden Research Laboratory, 2021 Santa Monica Blvd, Suite 740 East, Santa Monica, CA 90404, USA
    Antimicrob Agents Chemother 48:2149-52. 2004
    ..5 and 4 microg/ml, respectively; Propionibacterium spp. (n = 34), 0.125 and 0.5 microg/ml, respectively; Peptostreptococcus spp. (n = 52), 0.125 and 0.5 microg/ml, respectively; and Corynebacterium spp. (n = 31), 0.03 and 0...
  99. ncbi Quinupristin/dalfopristin: a review of its use in the management of serious gram-positive infections
    H M Lamb
    Adis International Limited, Mairangi Bay, Auckland, New Zealand
    Drugs 58:1061-97. 1999
    ..faecium (VREF), drug-resistant Streptococcus pneumoniae, other streptococci, Clostridium perfringens and Peptostreptococcus spp...
  100. ncbi Features of severe periodontal disease in a teenager with Chédiak-Higashi syndrome
    E M Delcourt-Debruyne
    Faculté d Odontologie, Departement de parodontologie, Université Lille, France
    J Periodontol 71:816-24. 2000
    ..The complete syndrome includes oculocutaneous albinism with photophobia, neurologic features, recurrent infections, and enterocolitis...
  101. ncbi Electrophoresis of whole-cell soluble proteins of microorganisms isolated from bacteremias in endodontic therapy
    G J Debelian
    Department of Oral Biology, University of Oslo, Norway
    Eur J Oral Sci 104:540-6. 1996
    ..These included Propionibacterium acnes, Peptostreptococcus prevotii, Fusobacterium nucleatum, Prevotella intermedia...

Research Grants76

  1. Oral microbial associations in HIV+subjects
    BRUCE PASTER; Fiscal Year: 2003
    ..Bulleidia extructa and Dialister pneumosintes, and novel "uncultivable" phylotypes of the genera Dialister, Peptostreptococcus, Selenomonas, and members of the "uncultivable" phylum TM7...
  2. Natural antimicrobials against bacterial vaginosis
    Michael Chikindas; Fiscal Year: 2006
    ..depletion of lactobacilli, the major flora of a healthy vagina and the overgrowth of Gardnerella vaginalis, Peptostreptococcus spp. and Prevotella bivia. BV may lead to premature labor...
  3. Role of Bacterial Vaginosis in Preterm Delivery
    ROBIN ROSS; Fiscal Year: 2003
    ..Concentrations of the normally dominant Lactobacillus decrease while other microflora increase (Prevotella, Peptostreptococcus, Gardnerella, Mobiluncus)...
  4. B Cell Superantigen Immune Complex Tissue Inflammation
    Arnold Levinson; Fiscal Year: 2007
    ..For example, protein L, secreted by the anaerobic strain Peptostreptococcus magnus, reacts with the Fabs of most human Vk1+, Vk3+, and Vk4+ Igs and homologous murine Vk+ Igs...
  5. Three Periodontal Therapies in Current & Non-Smokers
    Anne Haffajee; Fiscal Year: 2007
    ..The proposed investigation should provide a model to examine methods that could be useful in treating compromised patients whether compromised by harmful habits such as smoking, systemic disease, or genetic background. ..
  6. Molecular Mechanism of F. Nucleatum Virulence
    Yiping Han; Fiscal Year: 2006
    ..Knowledge obtained from this study may enable future development of therapeutic agents to reduce the incidence of PD, PTB, and possibly other common systemic infections. ..
  7. Streptococcus mutans and Dental Caries in Native American Children
    David Drake; Fiscal Year: 2007
    ..We believe that this assessment of vertical transmission of specific SM clones using DNA fingerprinting approaches will provide valuable information on the acquisition of these cariogenic bacteria in these Native American children. ..
  8. Quantification of Host Markers in GCF Using CBIB
    Ricardo Teles; Fiscal Year: 2007
    ..Moreover, this methodology is at the forefront of new approaches in proteomics, and carries enormous promise for translational applications in the near future. ..
  9. Photodynamic Therapy for Endodontic Disinfection
    NIKOLAOS SOUKOS; Fiscal Year: 2007
    ..Photodynamic therapy may be an adjunctive procedure to kill residual root canal bacteria after their sensitization with a photoactive drug and their subsequent exposure to light. ..
  10. Biologic Basis of Refractory Periodontal Disease
    BRUCE PASTER; Fiscal Year: 2006
    ..Eliminating refractory disease would have an enormous impact on the total cost of delivering periodontal therapy. ..
  11. Identification of Uncultivated and Unrecognized Pathogens of Periodontitis
    Anne Haffajee; Fiscal Year: 2007
    ..The identification of such pathogens should, over time, lead to better diagnosis of disease, optimal treatment strategies for the individual patient, new therapeutic approaches and carefully targeted approaches to prevention. ..
  12. The Acquisition of Bacterial Vaginosis in Lesbians
    Jeanne Marrazzo; Fiscal Year: 2006
    ..Lesbian couples provide a unique opportunity to conduct comparative studies of vaginal microbial ecology in sex partners, and to directly analyze determinants of transmission. ..
  13. Gene Expression in Chronic and Aggressive Periodontitis
    Panos Papapanou; Fiscal Year: 2006
    ..Ultimately, a pathobiology-based classification of periodontitis will facilitate correct diagnosis and targeted, efficient therapeutic prevention and intervention strategies. ..
  14. MOLECULAR BASIS OF VIRULENCE FACTORS OF ORAL FUNGAL SP.
    Mary Ann Jabra Rizk; Fiscal Year: 2006
    ..Long range plans include using the mutants generated to study Candida mannoprotein-specific host immunomodulation, such as stimulation of cytokines and chemokines. ..
  15. Oral Microbial Biomarkers in Periodontal Disease Progression
    Bruce J Paster; Fiscal Year: 2010
    ..The proposed research will determine if the bacterial composition of dental plaque can be used as an early warning signal for gum diseases. Based on this information, dentists can better treat and prevent these diseases. ..
  16. Candida albicans and Staphylococcus aureus dual species biofilms
    MARY ANN Y JABRA RIZK; Fiscal Year: 2010
    ..We expect the findings generated from the accomplishment of this work to aid in the design of novel therapeutic strategies to combat polymicrobial infections. ..
  17. Investigation of FadA adhesin from Fusobacterium nucleatum
    Yiping W Han; Fiscal Year: 2010
    ..Identification of host components and pathways affected by FadA will facilitate therapeutic development of modulate specific cellular processes and targeted drug delivery. ..
  18. Streptococcus mutans and Dental Caries in Native American Children
    DAVID RAY DRAKE; Fiscal Year: 2010
    ..We believe that this assessment of vertical transmission of specific SM clones using DNA fingerprinting approaches will provide valuable information on the acquisition of these cariogenic bacteria in these Native American children. ..
  19. Identification of Uncultivated and Unrecognized Pathogens of Periodontitis
    Anne Haffajee; Fiscal Year: 2009
    ..The identification of such pathogens should, over time, lead to better diagnosis of disease, optimal treatment strategies for the individual patient, new therapeutic approaches and carefully targeted approaches to prevention. ..
  20. Photodynamic Therapy for Endodontic Disinfection
    NIKOLAOS SOUKOS; Fiscal Year: 2009
    ..Photodynamic therapy may be an adjunctive procedure to kill residual root canal bacteria after their sensitization with a photoactive drug and their subsequent exposure to light. ..
  21. Photosensitization of Oral Bacteria
    NIKOLAOS SOUKOS; Fiscal Year: 2004
    ..In the same biofilm models the photodynamic effects of the PS will be established and PW-enhanced photosensitization of periodontopathogens by the PS will be evaluated. ..
  22. BIOLOGIC BASES OF REFRACTORY PERIODONTAL DIS
    BRUCE PASTER; Fiscal Year: 2000
    ..4) Identify more than 1 disease syndromes within the refractory group based upon microbial and host markers. ..
  23. MICROBIAL ASSOCIATIONS IN PERIODONTAL HEALTH AND DISEASE
    Anne Haffajee; Fiscal Year: 2000
    ..In addition the importance and biological basis of supragingival plaque control in the treatment and prevention of periodontal diseases and in maintaining stability of the periodontium will be determined. ..
  24. F.nucleatum in Amniotic Fluid Infection
    Yiping Han; Fiscal Year: 2004
    ..nucleatum for diagnostic purposes, and intervention studies aimed at reducing the incidence of preterm birth. ..
  25. Receptor Affects Fungal Mucosal Colonization in HIV
    Mary Ann Jabra Rizk; Fiscal Year: 2005
    ..dubliniensis to be preferentially selected. ..
  26. MICROBIAL ASSOCIATIONS IN PERIODONTAL HEALTH AND DISEASE
    Anne Haffajee; Fiscal Year: 2006
    ..These data will provide a basis for understanding microbial community structure, ecological relationships and define desired microbiological end-point of therapy. ..
  27. Identification of Uncultivated and Unrecognized Pathogens of Periodontitis
    ANNE DENISE HAFFAJEE; Fiscal Year: 2010
    ..The identification of such pathogens should, over time, lead to better diagnosis of disease, optimal treatment strategies for the individual patient, new therapeutic approaches and carefully targeted approaches to prevention. ..
  28. EFFECT OF ANTIBIOTICS ON ORAL BIOFILMS IN VIVO
    Anne Haffajee; Fiscal Year: 2001
    ..abstract_text> ..