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| aeromonasSummarySummary: A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria that occurs singly, in pairs, or in short chains. Its organisms are found in fresh water and sewage and are pathogenic to humans, frogs, and fish. Top Publications
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The genus Aeromonas: taxonomy, pathogenicity, and infectionJ Michael Janda
Microbial Diseases Laboratory, Division of Communicable Disease Control, Center for Infectious Diseases, California Department of Public Health, Richmond, California 94804, USA
Clin Microbiol Rev 23:35-73. 2010Over the past decade, the genus Aeromonas has undergone a number of significant changes of practical importance to clinical microbiologists and scientists alike...
Plasmid-mediated quinolone resistance in Aeromonas allosaccharophila recovered from a Swiss lakeRenata Cristina Picão
Service de Bacteriologie Virologie, INSERM U914 Emerging Resistance to Antibiotics, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculté de Médecine et Université Paris Sud, K Bicêtre, France
J Antimicrob Chemother 62:948-50. 2008To search for plasmid-mediated qnr genes among waterborne environmental Aeromonas spp. recovered from Switzerland.
Evolutionary and diagnostic implications of intragenomic heterogeneity in the 16S rRNA gene in Aeromonas strainsAlessia Morandi
Institute for Infectious Diseases, University of Berne, Switzerland
J Bacteriol 187:6561-4. 2005Sequencing 16S rRNA genes (SSU) cloned from Aeromonas strains revealed that strains contained up to six copies differing by < or = 1.5%...
Unexpected occurrence of plasmid-mediated quinolone resistance determinants in environmental Aeromonas sppVincent Cattoir
Institut Nationale de la Santé et de la Recherche Médicale Unité 914, Le Kremlin Bicetre, France
Emerg Infect Dis 14:231-7. 2008..The qnrS2 genes were identified from Aeromonas punctata subsp. punctata and A. media...
qnrVC-like gene located in a novel complex class 1 integron harboring the ISCR1 element in an Aeromonas punctata strain from an aquatic environment in Shandong Province, ChinaRuirui Xia
The State Key Laboratory of Microbial Technology, School of Life Science, Shandong University, 27 Shanda Nanlu, Jinan 250100, Shandong, People s Republic of China
Antimicrob Agents Chemother 54:3471-4. 2010..array following the ISCR1 element and bla(PER-1) in a multidrug-resistant strain of the aquatic bacterium Aeromonas punctata...
Distribution of six virulence factors in Aeromonas species isolated from US drinking water utilities: a PCR identificationK Sen
Technical Support Center, Office of Water, USA EPA, Cincinnati, OH 45268, USA
J Appl Microbiol 97:1077-86. 2004To examine whether Aeromonas bacteria isolated from municipally treated water had virulence factor genes.
Aeromonas aquariorum is widely distributed in clinical and environmental specimens and can be misidentified as Aeromonas hydrophilaMax Aravena-Roman
Division of Microbiology and Infectious Diseases, PathWest Laboratory Medicine WA, Locked Bag 2009, Nedlands WA 6009, Australia
J Clin Microbiol 49:3006-8. 2011Genotypic characterization of 215 Aeromonas strains (143 clinical, 52 environmental, and 20 reference strains) showed that Aeromonas aquariorum (60 strains, 30...
Expression of Aeromonas caviae ST pyruvate dehydrogenase complex components mediate tellurite resistance in Escherichia coliMiguel E Castro
Laboratorio de Microbiologia Molecular, Departamento de Biologia, Facultad de Quimica y Biologia, Universidad de Santiago de Chile, Casilla 40, Correo 33, Santiago, Chile
Biochem Biophys Res Commun 380:148-52. 2009..We previously reported that the lpdA gene product of the tellurite-resistant environmental isolate Aeromonas caviae ST is involved in the reduction of tellurite to elemental tellurium...
Analysis of 16S-23S intergenic spacer regions and rrn operon copy number of Aeromonas culicicola MTCC 3249TVyankatesh J Pidiyar
Molecular Biology Unit, National Centre for Cell Science, University of Pune, Ganeshkhind, Pune, Maharashtra 411 007, India
DNA Seq 14:183-94. 2003..coli. The upstream and downstream regions of 23S rRNA gene in the strain showed high sequence similarity with A. hydrophila and E. coli indicating their importance in processing of rRNA molecules...
Aeromonas aquariorum sp. nov., isolated from aquaria of ornamental fishA J Martinez-Murcia
Molecular Diagnostics Center, Biomolecular Technologies S L and Universidad Miguel Hernández, E 03300 Orihuela Alicante, Spain
Int J Syst Evol Microbiol 58:1169-75. 2008During a survey to determine the prevalence of Aeromonas strains in water and skin of imported ornamental fish, 48 strains presumptively identified as Aeromonas were isolated but they could not be identified as members of any previously ..
Aeromonas spp. and traveler's diarrhea: clinical features and antimicrobial resistanceJordi Vila
Microbiology Laboratory, Institute of Infections and Immunology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Villaroel 170, 08036 Barcelona, Spain
Emerg Infect Dis 9:552-5. 2003Traveler's diarrhea is the most common health problem of international travelers. We determined the prevalence of Aeromonas spp...
Type III secretion genes in Aeromonas salmonicida subsp salmonicida are located on a large thermolabile virulence plasmidKatja Stuber
Institute of Veterinary Bacteriology. Center for Fish and Wildlife Health, Institute of Animal Pathology, University of Bern, CH-3001 Bern, Switzerland
J Clin Microbiol 41:3854-6. 2003Type III secretion genes in Aeromonas salmonicida subsp. salmonicida are located on a large plasmid of approximately 140 kb...
Phylogenetic analysis of the genus Aeromonas based on two housekeeping genesL Soler
, , Facultad de Medicina y Ciencias de la Salud, Universidad Rovira y Virgili, Reus, E-43201 Tarragona, Spain
Int J Syst Evol Microbiol 54:1511-9. 2004The phylogenetic relationships of all known species of the genus Aeromonas, and especially Aeromonas bestiarum and Aeromonas salmonicida, were investigated on 70 strains using the rpoD sequence, which encodes the sigma70 factor...
Extended method for discrimination of Aeromonas spp. by 16S rDNA RFLP analysisM J Figueras
Departamento de Ciencias Medicas Basicas, Facultad de Medicina y Ciencias de la Salud, Universidad Rovira y Virgili, Reus, Spain
Int J Syst Evol Microbiol 50:2069-73. 2000A previously described molecular method, based on 16S rDNA RFLP analysis, for the identification of Aeromonas spp...
Analysis of 16S rRNA gene mutations in a subset of Aeromonas strains and their impact in species delineationAnabel Alperi
Department of Microbiology, Rovira Virgili University, Reus, Spain
Int Microbiol 11:185-94. 2008Characterization of 999 Aeromonas strains using a published 16S rDNA RFLP identification method showed that 8...
Aeromonas spp. clinical microbiology and diseaseJennifer L Parker
Academic Unit of Immunology and Infectious Diseases, Department of Infection and Immunity, University of Sheffield Medical School, Beech Hill Road, Sheffield S10 2RX, UK
J Infect 62:109-18. 2011Members of the genus Aeromonas inhabit various aquatic environments and are responsible for, and are implicated in, a number of intestinal and extra-intestinal infections in humans as well as other animals...
Quorum sensing in Aeromonas species isolated from patients in MalaysiaKok Gan Chan
Institute of Biological Sciences Division of Genetics and Molecular Biology, Faculty of Science, University of Malaya, 50603, Kuala Lumpur, Malaysia
Curr Microbiol 62:167-72. 2011..We determined AHL production in 22 Aeromonas strains isolated from various infected sites from patients (bile, blood, peritoneal fluid, pus, stool and urine)...
The genus Aeromonas: biochemical characteristics, atypical reactions, and phenotypic identification schemesSharon L Abbott
Microbial Diseases Laboratory, Division of Communicable Disease Control, California Department of Health Services, Richmond, California 94804, USA
J Clin Microbiol 41:2348-57. 2003A total of 193 strains representing 14 different Aeromonas genomospecies were evaluated for 63 phenotypic properties to create useful tables for the reference identification of mesophilic aeromonads...
Functional Tn5393-like transposon in the R plasmid pRAS2 from the fish pathogen Aeromonas salmonicida subspecies salmonicida isolated in NorwayT M L'Abée-Lund
Department of Pharmacology, Microbiology, and Food Hygiene, Norwegian School of Veterinary Science, 0033 Oslo, Norway
Appl Environ Microbiol 66:5533-5. 2000Tn5393c containing strA-strB was identified as part of R plasmid pRAS2 from the fish pathogen Aeromonas salmonicida subsp. salmonicida...
The role of Aeromonas in diarrhea: a reviewA von Graevenitz
Institute of Medical Microbiology, University of Zurich, 8028, Zurich, Switzerland
Infection 35:59-64. 2007The evidence for an enteropathogenic role of Aeromonas spp. is still controversial...
Clinical significance and distribution of putative virulence markers of 116 consecutive clinical Aeromonas isolates in southern TaiwanChi Jung Wu
Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan
J Infect 54:151-8. 2007The objectives of this study were to elucidate the clinical manifestations of Aeromonas infections and the association of putative virulence genes with clinical invasiveness.
Further studies on biochemical characteristics and serologic properties of the genus AeromonasJ M Janda
Microbial Diseases Laboratory, California Department of Health Services, Berkeley 94704 1011, USA
J Clin Microbiol 34:1930-3. 1996We characterized a collection of 268 Aeromonas isolates from diverse sources (clinical, animal, and environmental sources) for their species and serogroup designations...
Prevalence of genes encoding the type three secretion system and the effectors AexT and AexU in the Aeromonas veronii groupAdam C Silver
Department of Molecular and Cell Biology, University of Connecticut, Storrs, 06269, USA
DNA Cell Biol 28:383-8. 2009..factors, the type III secretion system (T3SS) and two T3SS-dependent toxins, AexT and AexU, was evaluated in the Aeromonas veronii group (AVG)...
Phylogenetic affiliation of Aeromonas culicicola MTCC 3249(T) based on gyrB gene sequence and PCR-amplicon sequence analysis of cytolytic enterotoxin geneVyankatesh J Pidiyar
Molecular Biology Unit, National Centre for Cell Science, University of Pune, Ganeshkhind, Pune, Maharashtra, India
Syst Appl Microbiol 26:197-202. 2003We determined the gyrB gene sequences of all 17 hybridizations groups of Aeromonas. Phylogenetic trees showing the evolutionary relatedness of gyrB and 16S rRNA genes in the type strains of Aeromonas were compared...
Aeromonas spp associated with children's diarrhoea in Tehran: a case-control studyMohammad Mehdi Soltan Dallal
Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Ann Trop Paediatr 24:45-51. 2004The study sought a possible pathogenic role for Aeromonas spp in Tehranian children presenting with diarrhoea...
A novel TTX-producing Aeromonas isolated from the ovary of Takifugu obscurusGuimei Yang
Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Shanghai Ocean University, Ministry of Education, Shanghai 201306, China
Toxicon 56:324-9. 2010..An Aeromonas strain was isolated from the ovary of the puffer fish and was shown to produce tetrodotoxin; this strain was ..
Accuracy of 6 commercial systems for identifying clinical Aeromonas isolatesBrigitte Lamy
Centre Hospitalier du Bassin de Thau, Laboratoire de Biologie, Sete, France
Diagn Microbiol Infect Dis 67:9-14. 2010We compared the accuracy of 6 commercial systems for Aeromonas identification by testing 87 clinical isolates in routine conditions, using partial rpoB gene sequencing as the reference standard...
An unusually high level of quinolone resistance associated with type II topoisomerase mutations in quinolone resistance-determining regions of Aeromonas caviae isolated from diarrhoeal patientsSutapa Sinha
National Institute of Cholera and Enteric Diseases, Beliaghata, Kolkata 700 010, India
Res Microbiol 155:827-9. 2004We examined 158 strains belonging to different Aeromonas species isolated from hospitalized acute diarrhoea cases for susceptibility to quinolones. Compared to other species, a high percentage of the A...
Characterization of class 1 integrons associated with R-plasmids in clinical Aeromonas salmonicida isolates from various geographical areasA S Schmidt
Department of Veterinary Microbiology, and Danish Institute of Fisheries Research, The Royal VeterinFary and Agricultural University, Stigbøjlen 4, DK 1870 Frederiksberg C, Denmark
J Antimicrob Chemother 47:735-43. 2001Class 1 integrons were found in 26 of 40 antibiotic-resistant isolates of the fish pathogen Aeromonas salmonicida from Northern Europe and North America...
Mechanisms of quinolone resistance in Aeromonas species isolated from humans, water and eelsElena Alcaide
Departamento de Microbiologia y Ecologia, Universitat de Valencia, C Doctor Moliner 50, E 46100 Burjassot, Valencia, Spain
Res Microbiol 161:40-5. 2010Mechanisms of resistance were determined in 33 quinolone-resistant isolates of the species Aeromonas hydrophila, Aeromonas caviae, Aeromonas media, Aeromonas salmonicida, Aeromonas popoffii and Aeromonas veronii, recovered from humans, ..
Divergent evolution and purifying selection of the flaA gene sequences in AeromonasMaribel Farfán
Departament de Microbiologia i Parasitologia Sanitaries, Facultat de Farmacia, Universitat de Barcelona, Av Joan XXIII s n, 08028 Barcelona, Spain
Biol Direct 4:23. 2009..Flagellar sequence variation constitutes a marker with widespread potential uses for studies of population genetics and phylogeny of bacterial species...
Symbiosis of Aeromonas veronii biovar sobria and Hirudo medicinalis, the medicinal leech: a novel model for digestive tract associationsJ Graf
Institute for Medical Microbiology, University of Berne, Switzerland
Infect Immun 67:1-7. 1999Hirudo medicinalis, the medicinal leech, is applied postoperatively in modern medicine. Infections by Aeromonas occur in up to 20% of patients unless a preemptive antibiotic treatment is administered...
New DNA-DNA hybridization and phenotypic data on the species Aeromonas ichthiosmia and Aeromonas allosaccharophila: A. ichthiosmia Schubert et al. 1990 is a later synonym of A. veronii Hickman-Brenner et al. 1987G Huys
Laboratory of Microbiology, Ghent University, Belgium
Syst Appl Microbiol 24:177-82. 2001..Fragment Length Polymorphism (AFLP) analysis has revealed a possible genotypic resemblance of the species Aeromonas ichthiosmia and Aeromonas allosaccharophila to Aeromonas veronii (Huys et al., Int. J. Syst. Bacteriol...
Identification of Aeromonas veronii genes required for colonization of the medicinal leech, Hirudo verbanaAdam C Silver
Department of Molecular and Cell Biology, University of Connecticut, 91 N Eagleville Rd, Unit 3125, Storrs, CT 06269, USA
J Bacteriol 189:6763-72. 2007..model system because it harbors a simple microbial community in the crop, comprising the genetically amenable Aeromonas veronii and a Rikenella-like bacterium...
Selective preparation of N-acetyl-D-glucosamine and N,N'-diacetylchitobiose from chitin using a crude enzyme preparation from Aeromonas spJu Hee Kuk
Glucosamine Saccharide Materials-National Research Laboratory (GSM-NRL, Division of Applied Bioscience and Biotechnology, Institute of Agricultural Science and Technology, Chonnam National University, 500-757, Gwangju, Korea
Biotechnol Lett 27:7-11. 2005A bacterium, Aeromonas sp. GJ-18, having strong chitinolytic activity was isolated from coastal soil and used for crude enzyme preparations. This enzyme preparation contained N-acetyl-D-glucosaminidase and N,N'-diacetylchitobiohydrolase...
The ADP-ribosylating toxin, AexT, from Aeromonas salmonicida subsp. salmonicida is translocated via a type III secretion pathwaySarah E Burr
Institute of Veterinary Bacteriology, University of Berne, CH-3012 Berne, Switzerland
J Bacteriol 185:6583-91. 2003AexT is an extracellular ADP ribosyltransferase produced by the fish pathogen Aeromonas salmonicida subsp. salmonicida. The protein is secreted by the bacterium via a recently identified type III secretion system...
Interaction between innate immune cells and a bacterial type III secretion system in mutualistic and pathogenic associationsAdam C Silver
Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06269, USA
Proc Natl Acad Sci U S A 104:9481-6. 2007..This simplicity renders it attractive for studying colonization factors. Aeromonas veronii, one of the leech symbionts, can be genetically manipulated and is a pathogen of mammals...
Isolation and identification of two novel SDS-resistant secreted chitinases from Aeromonas schubertiiChao Lin Liu
Graduate School of Biochemical Engineering, and Dept of Safety Health and Environmental Engineering, Mingchi University of Technology, Taipei, Taiwan, Republic of China
Biotechnol Prog 25:124-31. 2009Two SDS-resistant endochitinases, designated as ASCHI53 and ASCHI61, were isolated from Aeromonas schubertii in a soil sample from southern Taiwan...
Identity, virulence genes, and clonal relatedness of Aeromonas isolates from patients with diarrhea and drinking waterM Pablos
Department of Food Hygiene and Food Technology, Veterinary Faculty, University of Leon, Leon, Spain
Eur J Clin Microbiol Infect Dis 29:1163-72. 2010..to the Hospital of León (NW Spain) Microbiology and Parasitology Service, 32 (4%) were tested positive for Aeromonas spp. Mixed infections with other enteric pathogens occurred in 12 patients. A...
Aeromonas taiwanensis sp. nov. and Aeromonas sanarellii sp. nov., clinical species from TaiwanAnabel Alperi
Unit of Microbiology, Rovira i Virgili University, Sant Llorenc 21, Reus, Spain
Int J Syst Evol Microbiol 60:2048-55. 2010Two clinical Aeromonas strains (A2-50(T) and A2-67(T)) recovered from the wounds of two patients in Taiwan could not be assigned to any known species of this genus based on their 16S rRNA gene sequences, which showed similarities of 99...
Aeromonas flagella (polar and lateral) are enterocyte adhesins that contribute to biofilm formation on surfacesSylvia M Kirov
Discipline of Pathology, University of Tasmania, Hobart, Tasmania 7001, Australia
Infect Immun 72:1939-45. 2004b>Aeromonas spp. (gram-negative, aquatic bacteria which include enteropathogenic strains) have two distinct flagellar systems, namely a polar flagellum for swimming in liquid and multiple lateral flagella for swarming over surfaces...
The prevalence of Aeromonas species in feces of horses with diarrheaT L Hathcock
Department of Pathobiology, College of Veterinary Medicine, Auburn University, AL 36849, USA
J Vet Intern Med 13:357-60. 1999..and 34 horses without diarrhea were examined to determine if an association existed between isolation of Aeromonas spp. and diarrhea. Samples were also examined for Salmonella spp...
Complete sequence of the floR-carrying multiresistance plasmid pAB5S9 from freshwater Aeromonas bestiarumLaurence Gordon
INRA, ENVN, UMR1035 Chimiothérapie Aquacole et Environnement, F 44307 Nantes, France
J Antimicrob Chemother 62:65-71. 2008A multiresistant Aeromonas bestiarum strain, shown to be persistent and spreading in a freshwater stream, was investigated for the presence, location and organization of antimicrobial resistance genes.
Distribution of virulence factors and molecular fingerprinting of Aeromonas species isolates from water and clinical samples: suggestive evidence of water-to-human transmissionBijay K Khajanchi
Department of Microbiology and Immunology, University of Texas Medical Branch, Medical Research Building, 301 University Boulevard, Galveston, TX 77555 1070, USA
Appl Environ Microbiol 76:2313-25. 2010A total of 227 isolates of Aeromonas obtained from different geographical locations in the United States and different parts of the world, including 28 reference strains, were analyzed to determine the presence of various virulence ..
Identification of Aeromonas trota (hybridization group 13) by amplification of the aerolysin gene using polymerase chain reactionA A Khan
National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079, USA
Mol Cell Probes 13:93-8. 1999b>Aeromonas trota is recognized as an important enteropathogen, and its haemolysin (aerolysin) is purported to be one of the virulence factors. Rapid detection and identification of A...
Immunological analysis of extracellular products and cell surface components of motile Aeromonas isolated from fishY Santos
Departamento de Microbiologia y Parasitologia, Facultad de Biologia, Universidad de Santiago, Spain
J Appl Bacteriol 81:585-93. 1996..the characterization of antigens present in the extracellular products (ECP) and cell wall of strains of motile Aeromonas isolated from rainbow trout culture systems...
Peptide hydrolysis by the binuclear zinc enzyme aminopeptidase from Aeromonas proteolytica: a density functional theory studyShi Lu Chen
Department of Theoretical Chemistry, School of Biotechnology, Royal Institute of Technology, AlbaNova SE 10691 Stockholm, Sweden
J Phys Chem B 112:2494-500. 2008Aminopeptidase from Aeromonas proteolytica (AAP) is a binuclear zinc enzyme that catalyzes the cleavage of the N-terminal amino acid residue of peptides and proteins...
The effect of intraperitoneally administered recombinant IL-1beta on immune parameters and resistance to Aeromonas salmonicida in the rainbow trout (Oncorhynchus mykiss)Suhee Hong
Department of Zoology, University of Aberdeen, Tillydrone Avenue, AB24 2TZ, Scotland, Aberdeen, UK
Dev Comp Immunol 27:801-12. 2003..Finally, resistance to Aeromonas salmonicida, the causative agent of furunculosis, was augmented at early times (2 days) post-injection of 1 ..
Aeromonas spp. human isolates induce apoptosis of murine macrophagesSylwia Krzyminska
Faculty of Biology, Department of Microbiology, A Mickiewicz University, ul Umultowska 89, 61 614 Poznan, Poland
Curr Microbiol 58:252-7. 2009Interactions of Aeromonas caviae, Aeromonas veronii biotype sobria, and Aeromonas hydrophila strains isolated from fecal specimens of humans with gastroenteritis on murine macrophages, J774 cells, were investigated...
In vitro antimicrobial susceptibility of clinical isolates of Aeromonas caviae, Aeromonas hydrophila and Aeromonas veronii biotype sobriaJordi Vila
J Antimicrob Chemother 49:701-2. 2002
Biochemical and molecular characterization of tetracycline-resistant Aeromonas veronii isolates from catfishMohamed Nawaz
Division of Microbiology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079, USA
Appl Environ Microbiol 72:6461-6. 2006Eighty-one tetracycline-resistant Aeromonas sp. strains were isolated from farm-raised catfish...
Molecular typing of Aeromonas isolates in natural mineral watersP Villari
Department of Experimental Medicine and Pathology, University La Sapienza, 00161 Rome, Italy
Appl Environ Microbiol 69:697-701. 2003A total of 103 isolates of Aeromonas spp...
Complete genome sequence of Aeromonas veronii strain B565Yanxia Li
Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, Tianjin 300457, People s Republic of China
J Bacteriol 193:3389-90. 2011b>Aeromonas veronii strain B565 was isolated from aquaculture pond sediment in China. We present here the complete genome sequence of B565 and compare it with 2 published genome sequences of pathogenic strains in the Aeromonas genus...
Characterization of Aeromonas trota strains that cross-react with Vibrio cholerae O139 BengalM J Albert
Laboratory Sciences Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
J Clin Microbiol 33:3119-23. 1995..cholerae serogroups O22 and O155. We detected six surface water isolates of Aeromonas trota that agglutinated in polyclonal antisera to V. cholerae O139 and V. cholerae O22 but not in antiserum to V...
Aeromonas septicemia after medicinal leech use following replantation of severed digitsSteven M Levine
Institute for Reconstructive Plastic Surgery, New York University Langone Medical Center, New York, New York 10016, USA
Am J Crit Care 19:469-71. 2010Medicinal leeches are used to control venous congestion. Aeromonas in the leech gut are essential for digestion of blood. This case report describes a patient who had Aeromonas bacteremia develop after leeching...
The structure of the O-specific polysaccharide from the lipopolysaccharide of Aeromonas bestiarum strain 207Anna Turska-Szewczuk
Department of Genetics and Microbiology, M Curie Sklodowska University, Akademicka 19, 20 033 Lublin, Poland
Carbohydr Res 345:680-4. 2010The O-specific polysaccharide obtained by mild-acid degradation of Aeromonas bestiarum 207 lipopolysaccharide was studied by sugar and methylation analyses along with (1)H and (13)C NMR spectroscopy...
Evaluation of recA sequencing for the classification of Aeromonas strains at the genotype levelA Sepe
Laboratory of Environmental Microbiology, Istituto Cantonale di Microbiologia, Bellinzona, Switzerland, and Università degli Studi dell Insubria, Varese, Italy
Lett Appl Microbiol 46:439-44. 2008To evaluate the usefulness of partial recA sequences for the identification of Aeromonas strains at the genotype level.
Aeromonas hydrophilia infections after penetrating foot traumaUlla-Britt Larka
Harris County Podiatric Surgical Residency and Fellowship Programs, Greater Texas Education Foundation, West Houston Medical Center, Houston, TX 77058, USA
J Foot Ankle Surg 42:305-8. 2003The bacterium Aeromonas hydrophila is an anaerobic gram-negative bacillus commonly found in natural bodies of water and can cause infection in patients who suffer water-associated trauma or in immunocompromised hosts...
Malate dehydrogenase: a useful phylogenetic marker for the genus AeromonasMaribel Farfán
Departament de Microbiologia i Parasitologia Sanitaries, Facultat de Farmacia, Universitat de Barcelona, Avda Joan XXIII s n, 08028 Barcelona, Spain
Syst Appl Microbiol 33:427-35. 2010..We have sequenced the full-length mdh gene in 36 type and reference strains of Aeromonas. The species grouping obtained in the phylogenetic tree derived from mdh sequences was in agreement with that ..
Assessment of genetic variability and relatedness among atypical Aeromonas salmonicida from marine fishes, using AFLP-fingerprintingVera Lund
Fiskeriforskning, Norwegian Institute of Fisheries and Aquaculture Ltd, Tromsø
Dis Aquat Organ 50:119-26. 2002Atypical strains of Aeromonas salmonicida are the causal agent of atypical furunculosis or ulcer disease in various fish species, including spotted wolffish Anarhichas minor, which is a promising species in the Norwegian fish-farming ..
Interactions of clinical and environmental Aeromonas isolates with Caco-2 and HT29 intestinal epithelial cellsC R A Couto
Departamento de Microbiologia, Imunologia e Parasitologia, Faculdade de Ciencias Medicas, Universidade do Estado do Rio de Janeiro, RJ, Brazil
Lett Appl Microbiol 45:405-10. 2007Evaluation of adherence and invasion of Aeromonas spp. to human colon carcinoma cell lines Caco-2 and HT29 and assessment of cytotoxic activity.
The dihydrolipoamide dehydrogenase of Aeromonas caviae ST exhibits NADH-dependent tellurite reductase activityMiguel E Castro
Laboratorio de Microbiologia Molecular, Departamento de Biologia, Facultad de Quimica y Biologia, Universidad de Santiago de Chile, Casilla 40, Correo 33, Santiago, Chile
Biochem Biophys Res Commun 375:91-4. 2008..Crude extracts prepared from the environmental isolate Aeromonas caviae ST catalize the in vitro reduction of TeO32- in a NADH-dependent reaction...
Crystallization and preliminary X-ray analysis of the controller protein C.AhdI from Aeromonas hydrophiliaJ E McGeehan
Biophysics Laboratories, Institute of Biomedical and Biomolecular Sciences, University of Portsmouth, Portsmouth PO1 2DT, England
Acta Crystallogr D Biol Crystallogr 60:323-5. 2004Single crystals of purified homodimeric controller protein from Aeromonas hydrophilia (C.AhdI) have been grown under several different conditions using vapour diffusion...
Use of the novel phylogenetic marker dnaJ and DNA-DNA hybridization to clarify interrelationships within the genus AeromonasPham Hong Nhung
Department of Microbiology, Regeneration and Advanced Medical Science, Gifu University Graduate School of Medicine, 1 1 Yanagido, Gifu 501 1194, Japan
Int J Syst Evol Microbiol 57:1232-7. 2007The interrelationships of 27 Aeromonas strains were investigated using dnaJ sequences and DNA-DNA hybridization...
Phylogenetic analysis and identification of Aeromonas species based on sequencing of the cpn60 universal targetDavid Miñana-Galbis
Departament de Microbiologia i Parasitologia Sanitaries, Facultat de Farmacia, Universitat de Barcelona, Av Joan XXIII s n, 08028 Barcelona, Spain
Int J Syst Evol Microbiol 59:1976-83. 2009..to evaluate its usefulness in phylogenetic and taxonomic studies and as an identification marker for the genus Aeromonas. Sequences of 555 bp, corresponding to the UT region, were obtained from a collection of 35 strains representing ..
Characterization of Aeromonas virulence using an immunocompromised mouse modelDennis J Lye
National Exposure Research Laboratory, Microbial and Chemical Exposure Assessment Research Division, United States Environmental Protection Agency, Cincinnati, OH 45268, USA
Curr Microbiol 54:195-8. 2007An immunocompromised mouse model was used to characterize Aeromonas strains for their ability to cause opportunistic, extraintestinal infections. A total of 34 isolates of Aeromonas (A. hydrophila [n = 12]), A...
Phylogenetic identification of Aeromonas strains isolated from carcasses of pig as new members of the species Aeromonas allosaccharophilaMaria José Saavedra
Department of Veterinary Sciences, CECAV University of Tras os Montes e Alto Douro, Vila Real, Portugal
Antonie Van Leeuwenhoek 91:159-67. 2007The first description of the species Aeromonas allosaccharophila was only based on two strains (the type strain CECT4199, and a duplicate CECT4200) isolated from diseased elvers (Anguilla anguilla) of an eel-farm located in Valencia, ..
Polymerase chain reaction (PCR)-based typing analysis of atypical isolates of the fish pathogen Aeromonas salmonicidaS Høie
Department of Fish Health, National Veterinary Institute, Oslo, Norway
Syst Appl Microbiol 22:403-11. 1999Two hundred and five isolates of atypical Aeromonas salmonicida, recovered from a wide range of hosts and countries were characterized by polymerase chain reaction (PCR) targeting four genes...
Structural basis for the kexin-like serine protease from Aeromonas sobria as sepsis-causing factorHidetomo Kobayashi
Laboratory of Molecular Microbiological Science, Faculty of Pharmaceutical Sciences, Hiroshima International University, Hiro Koshingai, Kure, Hiroshima 737 0112, Japan
J Biol Chem 284:27655-63. 2009The anaerobic bacterium Aeromonas sobria is known to cause potentially lethal septic shock. We recently proposed that A...
Clinical significance of spontaneous Aeromonas bacterial peritonitis in cirrhotic patients: a matched case-control studyJae Phil Choi
Division of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
Clin Infect Dis 47:66-72. 2008Although Aeromonas species are known to cause bacteremia in patients with cirrhosis, less is known about spontaneous bacterial peritonitis (SBP) caused by Aeromonas species in these patients.
Secreted enzymes of AeromonasJ M Pemberton
Department of Microbiology, University of Queensland, St Lucia, Australia
FEMS Microbiol Lett 152:1-10. 1997A hallmark characteristic of species of Aeromonas is their ability to secrete a wide variety of enzymes associated with pathogenicity and environmental adaptability...
The effect of various Aeromonas bestiarum vaccines on non-specific immune parameters and protection of carp (Cyprinus carpio L.)A Kozinska
Department of Fish Diseases, National Veterinary Research Institute, 24-100 Pulawy, Poland
Fish Shellfish Immunol 16:437-45. 2004b>Aeromonas bestiarum is one of the causal agents of motile aeromonad infection/motile aeromonad septicemia (MAI/MAS) in fish. Infections of the bacterium is an increasing problem in commercial carp (Cyprinus carpio L.) farmed in Poland...
DNA-DNA reassociation and phenotypic data indicate synonymy between Aeromonas enteropelogenes Schubert et al. 1990 and Aeromonas trota Carnahan et al. 1991Geert Huys
Laboratory of Microbiology, Ghent University, K L Ledeganckstr 35, B 9000 Ghent, Belgium
Int J Syst Evol Microbiol 52:1969-72. 2002Mainly on the basis of phylogenetic and genotypic evidence, it has been suggested previously that the species Aeromonas enteropelogenes Schubert et al. 1990 is identical to the species Aeromonas trota Carnahan et al. 1991...
Simultaneous detection of Aeromonas salmonicida, Flavobacterium psychrophilum, and Yersinia ruckeri, three major fish pathogens, by multiplex PCRA Del Cerro
, , Facultad de Medicina, , Universidad de Oviedo, Spain
Appl Environ Microbiol 68:5177-80. 2002..assay based on the 16S rRNA genes was developed for the simultaneous detection of three major fish pathogens, Aeromonas salmonicida, Flavobacterium psychrophilum, and Yersinia ruckeri...
An Aeromonas caviae genomic island is required for both O-antigen lipopolysaccharide biosynthesis and flagellin glycosylationS Mohammed B Tabei
Unit of Infection and Immunity, School of Medicine and Biomedical Sciences, University of Sheffield, Sheffield S10 2RX, United Kingdom
J Bacteriol 191:2851-63. 2009b>Aeromonas caviae Sch3N possesses a small genomic island that is involved in both flagellin glycosylation and lipopolysaccharide (LPS) O-antigen biosynthesis...
Comparative study of cytotoxicity of Aeromonas spp. on four different cell linesS Ghatak
Division of Veterinary Public Health, Indian Veterinary Research Institute, Izatnagar, India
Comp Immunol Microbiol Infect Dis 29:233-41. 2006In vitro cytotoxicity is an important virulence property of motile mesophilic Aeromonas species. Cell-free supernatant prepared from 55 Aeromonas isolates including one A...
Different clinical characteristics between polymicrobial and monomicrobial Aeromonas bacteremia--a study of 216 casesChorng Jang Lay
Division of Infectious Disease, Department of Medicine, Buddhist Dalin Tzu Chi General Hospital, Chiayi, Taiwan
Intern Med 49:2415-21. 2010Part of Aeromonas bacteremia is polymicrobial infection. However, a clinical comparison of monomicrobial and polymicrobial Aeromonas bacteremia has not hitherto been reported.
Nucleotide and amino acid sequences of the metallo-beta-lactamase, ImiS, from Aeromonas veronii bv. sobriaT R Walsh
Bristol Centre for Antimicrobial Research and Evaluation, Department of Microbiology and Pathology, Medical School, University of Bristol, United Kingdom
Antimicrob Agents Chemother 42:436-9. 1998The Aeromonas veronii bv. sobria metallo-beta-lactamase gene, imiS, was cloned...
Chemical structure of aeromonas gum--extracellular polysaccharide from Aeromonas nichidenii 5797Xiaojuan Xu
Department of Chemistry, Wuhan University, 430072, China
Carbohydr Res 339:1631-6. 2004b>Aeromonas (A) gum, an extracellular heteropolysaccharide produced by the bacterium Aeromonas nichidenii strain 5797, was studied by 1H and 13C NMR spectroscopy including 2D COSY, TOCSY, 1H, 13C HMQC, HMBC and ROESY experiments after O-..
[Isolation and identification of pathogenic Aeromonas veronii isolated from infected Siberian sturgeon (Acipenser baerii)]Zhihong Ma
Beijing Fisheries Research Institute, Beijing Academy of Agriculture and Forestry Sciences, Beijing 100068, China
Wei Sheng Wu Xue Bao 49:1289-94. 2009..Our study aimed at searching for the pathogenic factor causing Siberian sturgeon (Acipenser baerii) disease...
Genetic relationships of Aeromonas strains inferred from 16S rRNA, gyrB and rpoB gene sequencesMara Küpfer
Cantonal Institute of Microbiology, Microbial Ecology, CH 6500 Bellinzona, Switzerland
Int J Syst Evol Microbiol 56:2743-51. 2006Genetic relationships among bacterial strains belonging to the genus Aeromonas were inferred from 16S rRNA, gyrB and rpoB gene sequences...
Lack of agreement between biochemical and genetic identification of Aeromonas sppOyvind Ormen
Department of Food Safety and Infection Biology, The Norwegian School of Veterinary Science, N 0033 Oslo, Norway
APMIS 113:203-7. 2005..the PCR-amplified 16S r-RNA sequence were compared for a selection of 171 clinical and environmental isolates of Aeromonas spp. The investigation revealed large differences between the two methods...
Human isolates of Aeromonas possess Shiga toxin genes (stx1 and stx2) highly similar to the most virulent gene variants of Escherichia coliA Alperi
Departament de Ciencies Mediques Basiques, Facultat de Medicina i Ciencies de la Salut, IISPV, Universitat Rovira i Virgili, Reus, Spain
Clin Microbiol Infect 16:1563-7. 2010..PCR screening of 80 clinical Aeromonas strains showed that 19 were stx1-positive and only one was positive for both stx1 and stx2...
In vivo evolution of the Aeromonas punctata polyhydroxyalkanoate (PHA) synthase: isolation and characterization of modified PHA synthases with enhanced activityA A Amara
, Corrensstrasse 3, , Germany
Appl Microbiol Biotechnol 59:477-82. 2002In vivo random mutagenesis of the polyhydroxyalkanoate (PHA) synthase gene from Aeromonas punctata was performed employing the mutator strain Escherichia coli XL1-Red...
Secondary Aeromonas peritonitis is associated with polymicrobial ascites culture and absence of liver cirrhosis compared to primary Aeromonas peritonitisLing-Ju Huang
Section of Infectious Diseases, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China
APMIS 114:772-8. 2006b>Aeromonas peritonitis remains a rare condition. In this study we describe the clinical features of primary and secondary Aeromonas peritonitis, and compare the differences between these two diseases entities...
Bacteraemia caused by non-glucose-fermenting gram-negative bacilli and Aeromonas species in patients with haematological malignancies and solid tumoursR Martino
Servei d Hematologia Clinica, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
Eur J Clin Microbiol Infect Dis 19:320-3. 2000..The clinical characteristics and outcome of bacteraemia caused by non-glucose-fermenting gram-negative bacilli and Aeromonas spp. were examined in 115 adults with haematological malignancies or solid tumours...
Characterization of an ADP-ribosyltransferase toxin (AexT) from Aeromonas salmonicida subsp. salmonicidaMartin Braun
Institute for Veterinary Bacteriology, Center for Fish and Wildlife Health, University of Bern, CH-3012 Bern, Switzerland
J Bacteriol 184:1851-8. 2002An ADP-ribosylating toxin named Aeromonas salmonicida exoenzyme T (AexT) in A. salmonicida subsp. salmonicida, the etiological agent of furunculosis in fish, was characterized...
Structural characterization of the O-chain polysaccharide of Aeromonas caviae ATCC 15468 lipopolysaccharideZhan Wang
Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario, Canada
Carbohydr Res 343:483-8. 2008The O-chain polysaccharide produced by a mild acid degradation of Aeromonas caviae ATCC 15468 lipopolysaccharide was found to be composed of L-rhamnose, 2-acetamido-2-deoxy-D-glucose, 2-acetamido-2-deoxy-D-galactose and phosphoglycerol...
Structure of the Aeromonas toxin proaerolysin in its water-soluble and membrane-channel statesM W Parker
St Vincent s Institute of Medical Research, Fitzroy, Victoria, Australia
Nature 367:292-5. 1994Aerolysin is chiefly responsible for the pathogenicity of Aeromonas hydrophila, a bacterium associated with diarrhoeal diseases and deep wound infections...
Phenotypic characteristics and pathogenicity of Aeromonas genomospecies isolated from common carp (Cyprinus carpio L.)A Kozinska
Department of Fish Disease, National Veterinary Research Institute, Putawy, Poland
J Appl Microbiol 93:1034-41. 2002To evaluate the relationship between the genomospecies, phenotypic profile and pathogenicity for carp of 37 motile Aeromonas strains.
Delayed leech-borne infection with Aeromonas hydrophilia in escharotic flap woundB Ardehali
Department of Plastic and Reconstructive Surgery, Charing Cross Hospital, Fulham Palace Road, Hammersmith, London W6 8AF, UK
J Plast Reconstr Aesthet Surg 59:94-5. 2006..1]. We describe a case of delayed leech-borne infection, from the escharotic portion of a latissimus dorsi flap, which developed several days after stopping leech therapy for venous congestion in a reconstructed breast...
Factors affecting biosurfactant production by oil degrading Aeromonas spp. isolated from a tropical environmentM O Ilori
Department of Botany, Faculty of Science, University of Lagos, Akoka, Yaba, Lagos, Lagos State 101017, Nigeria
Chemosphere 61:985-92. 2005An Aeromonas spp. was isolated from tropical estuarine water. The organism grew on crude oil and produced biosurfactant that could emulsify hydrocarbons. The peak growth and biosurfactant production was on the 8th day...
Induction of apoptosis in Vero cells by Aeromonas veronii biovar sobria vacuolating cytotoxic factorLuciano Moura Martins
Departamento de Microbiologia e Imunologia, Instituto de Biologia, Havana, Cuba
FEMS Immunol Med Microbiol 49:197-204. 2007Recently, a cytotoxin named vacuolating cytotoxic factor (VCF) in Aeromonas sobria and Aeromonas veronii biovar sobria was described. We have now purified this factor using ion metallic affinity chromatography...
Characterization of integrons and tetracycline resistance determinants in Aeromonas spp. isolated from South African aquaculture systemsLiezl Jacobs
Department of Microbiology, University of Stellenbosch, Private Bag X1, Matieland 7602, South Africa
Int J Food Microbiol 114:295-306. 2007An increasing incidence of multidrug resistance amongst Aeromonas spp. isolates, which are both fish pathogens and emerging opportunistic human pathogens, has been observed worldwide...
Updated phylogeny of the genus AeromonasM J Saavedra
Molecular Diagnostics Center (MDC, , 03300 Orihuela, Alicante, Spain
Int J Syst Evol Microbiol 56:2481-7. 2006Recent phylogenetic studies of the genus Aeromonas based on gyrB and rpoD gene sequences have improved the phylogeny based on 16S rRNA gene sequences first published in 1992, particularly in the ability to split closely related species...
Molecular characterization and quantitative analysis of superoxide dismutases in virulent and avirulent strains of Aeromonas salmonicida subsp. salmonicidaA Dacanay
Institute for Marine Biosciences, National Research Council, Halifax, Nova Scotia, Canada
J Bacteriol 185:4336-44. 2003b>Aeromonas salmonicida subsp...
PCR-based assays for the fish pathogen Aeromonas salmonicida. II. Further evaluation and validation of three PCR primer sets with infected fishHelen K Byers
Australian Animal Health Laboratory, CSIRO Livestock Industries, Geelong, Vic
Dis Aquat Organ 49:139-44. 2002Two Aeromonas salmonicida-specific polymerase chain reaction (PCR) tests and 1 A. salmonicida subsp. salmonicida-specific PCR test were used to screen salmonid populations that were either overtly or covertly infected with A...
PCR-based assays for the fish pathogen Aeromonas salmonicida. I. Evaluation of three PCR primer sets for detection and identificationHelen K Byers
Australian Animal Health Laboratory, CSIRO Livestock Industries, Geelong, Victoria
Dis Aquat Organ 49:129-38. 2002In an effort to develop a rapid diagnostic test for the fish pathogen Aeromonas salmonicida, the performance of 2 polymerase chain reaction (PCR) primer sets (AP and PAAS) targeting the fish pathogen A...
Virulence and resistance markers in clinical and environmental Aeromonas strains isolated in RomaniaMariana Carmen Chifiriuc
Cantacuzino Institute
Roum Arch Microbiol Immunol 66:69-79. 2007The virulence and resistance (R) features of 37 Aeromonas strains from diarrheal cases and 150 from the aquatic environment (isolated during cold and warm season) were tested at different incubation temperatures (4 degrees C, 28 degrees ..
Virulence markers in Aeromonas hydrophila and Aeromonas veronii biovar sobria isolates from freshwater fish and from a diarrhoea caseC J González-Serrano
Department of Food Hygiene and Food Technology, Veterinary Faculty, University of Leon, Leon, Spain
J Appl Microbiol 93:414-9. 2002To evaluate the public health significance of representative strains of two Aeromonas spp., mainly from freshwater fish, on the basis of production of virulence-associated factors and presence of the haemolytic genes aerA and hlyA.
PCR detection of potentially pathogenic aeromonads in raw and cold-smoked freshwater fishM N González-Rodríguez
Department of Food Hygiene and Food Technology, University of Leon, 24071 Leon, Spain
J Appl Microbiol 93:675-80. 2002..Development of a PCR assay for detection of aeromonads carrying the hlyA and/or aerA genes in fish...
Research Grants
- Salmonella polymicrobial interactionsBRIAN M AHMER; Fiscal Year: 2010..To date, we have determined that Salmonella can detect Aeromonas hydrophila in turtles and Yersinia enterocolitica in mice and pigs...
- Structural Basis for Bridged Bimetallic Enzyme CatalysisDagmar Ringe; Fiscal Year: 2007..We have selected two enzymes, Streptomyces olivochromogenes xylose isomerase (Xyl) and Aeromonas proteolytica aminopeptidase (AAP), as primary model systems for this investigation...
- Structural Basis for Bridged Bimetallic Enzyme CatalysisDagmar Ringe; Fiscal Year: 2009..We have selected two enzymes, Streptomyces olivochromogenes xylose isomerase (Xyl) and Aeromonas proteolytica aminopeptidase (AAP), as primary model systems for this investigation...
- Cytotoxic Enterotoxin in Aeromonas-mediated DiseasesASHOK CHOPRA; Fiscal Year: 2006b>Aeromonas is an emerging human pathogen, which causes gastroenteritis and septicemia...
- COORDINATION CHEMISTRY OF MICROBIAL IRON TRANSPORTKenneth Raymond; Fiscal Year: 2007..iron transport is a completely different kind of transport system first observed by this research group in Aeromonas hydrophila...
- Enzyme Catalysis & Bridged Bi-Metal MotifMichael Klein; Fiscal Year: 2007..Specifically, mechanistic models of Aeromonas proteolytica aminopeptidase (AAP) and arginase will be examined, as well as the structural and dynamical ..
- COORDINATION CHEMISTRY OF MICROBIAL ION TRANSPORTKenneth Raymond; Fiscal Year: 2003..We will study the role of amonabactin in the virulence of Aeromonas hydrophyla, a human pathogen...
- CYTOLYTIC ENTEROTOXIN OF AEROMONAS HYDROPHILAASHOK CHOPRA; Fiscal Year: 2000..the regulation of the Act gene either by fusing it with a reporter gene or by mutagenesis of the chromosome of Aeromonas using a transposon which imparts antibiotic resistance to screen for toxin negative mutants...
- Molecular basis of host-microbiota signaling in the zebrafish gutKaren Guillemin; Fiscal Year: 2009..in the zebrafish we have established a zebrafish mono-association model with a genetically tractable bacterium, Aeromonas veronii biovar sobria...
- Molecular basis of host-microbiota signaling in the zebrafish gutKAREN J GUILLEMIN; Fiscal Year: 2010..in the zebrafish we have established a zebrafish mono-association model with a genetically tractable bacterium, Aeromonas veronii biovar sobria...
- Molecular basis of host-microbiota signaling in the zebrafish gutKAREN J GUILLEMIN; Fiscal Year: 2010..in the zebrafish we have established a zebrafish mono-association model with a genetically tractable bacterium, Aeromonas veronii biovar sobria...
- Molecular basis of host-microbiota signaling in the zebrafish gutKaren Guillemin; Fiscal Year: 2009..in the zebrafish we have established a zebrafish mono-association model with a genetically tractable bacterium, Aeromonas veronii biovar sobria...
- Molecular basis of host-microbiota signaling in the zebrafish gutKaren Guillemin; Fiscal Year: 2007..in the zebrafish we have established a zebrafish mono-association model with a genetically tractable bacterium, Aeromonas veronii biovar sobria...
- Functional Analysis of a Digestive-Tract Microbiome During Dietary ChangesJOERG contact GRAF; Fiscal Year: 2011....
- Substrate & Inhibitor Binding in Leucine AminopeptidaseBrian Bennett; Fiscal Year: 2003..Specific Aim 4: Identify specific enzyme-substrate residue interactions (i.e. Sn-Pn) important for substrate binding, specificity and orientation. Systematic kinetic studies of hydrophobic site mutants will be carried out. ..
- Substrate & Inhibitor Binding in Leucine AminopeptidaseBrian Bennett; Fiscal Year: 2006..e. Sn-Pn) important for substrate binding, specificity and orientation. Systematic kinetic studies of hydrophobic site mutants will be carried out. ..
- Substrate & Inhibitor Binding in Leucine AminopeptidaseBrian Bennett; Fiscal Year: 2007..e. Sn-Pn) important for substrate binding, specificity and orientation. Systematic kinetic studies of hydrophobic site mutants will be carried out. ..
