fusobacteria

Summary

Summary: A phylum of anaerobic, gram-negative bacteria with a chemoorganotrophic heterotrophic metabolism. They are resident flora of the OROPHARYNX.

Top Publications

  1. ncbi Genotypic and phenotypic characterization of fusobacteria from Chinese and European patients with inflammatory periodontal diseases
    Rudolf Gmür
    Institute for Oral Biology, Center for Dental, Oral Medicine and Maxillofacial Surgery, University of Zurich, Plattenstrasse 11, CH 8032 Zurich, Switzerland
    Syst Appl Microbiol 29:120-30. 2006
  2. ncbi Two distinct proton binding sites in the ATP synthase family
    Christoph von Ballmoos
    Institut fur Mikrobiologie, ETH Zurich, Wolfgang Pauli Strasse 10, CH 8093 Zurich, Switzerland
    Biochemistry 46:11800-9. 2007
  3. ncbi Structural evidence for a constant c11 ring stoichiometry in the sodium F-ATP synthase
    Thomas Meier
    Institut fur Mikrobiologie, Eidgenossische Technische Hochschule, Zurich, Switzerland
    FEBS J 272:5474-83. 2005
  4. ncbi Bacterial reduction and persistence after endodontic treatment procedures
    M Sakamoto
    Microbe Division Japan Collection of Microorganisms, RIKEN BioResource Center, Wako, Saitama, Japan
    Oral Microbiol Immunol 22:19-23. 2007
  5. ncbi Culture-independent analysis of vaginal microflora: the unrecognized association of Atopobium vaginae with bacterial vaginosis
    Hans Verstraelen
    Department of Obstetrics and Gynaecology, Microbiology and Immunology, Ghent University, De Pintelaan 185, 9000 Ghent, Belgium
    Am J Obstet Gynecol 191:1130-2. 2004
  6. ncbi Validation of 16S rDNA sequencing in microdissected bowel biopsies from Crohn's disease patients to assess bacterial flora diversity
    G De Hertogh
    Department of Morphology and Molecular Pathology, University Hospitals KULeuven, Belgium
    J Pathol 209:532-9. 2006
  7. ncbi Novel ecological niche of Cetobacterium somerae, an anaerobic bacterium in the intestinal tracts of freshwater fish
    C Tsuchiya
    Department of Marine Science and Resources, Nihon University, Kameino, Fujisawa, Kanagawa, Japan
    Lett Appl Microbiol 46:43-8. 2008
  8. pmc Torque generation by the Fo motor of the sodium ATPase
    Jianhua Xing
    Department of Molecular Biology, Policy and Management, University of California, Berkeley, California 94720 3112, USA
    Biophys J 87:2148-63. 2004
  9. ncbi Metabolism of octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine by Clostridium bifermentans strain HAW-1 and several other H2-producing fermentative anaerobic bacteria
    Jian Shen Zhao
    Biotechnology Research Institute, National Research Council of Canada, 6100 Royalmount Avenue, Montreal, Que, Canada H4P 2R2
    FEMS Microbiol Lett 237:65-72. 2004
  10. doi Probing the rotor subunit interface of the ATP synthase from Ilyobacter tartaricus
    Denys Pogoryelov
    Institute of Microbiology, Eidgenossische Technische Hochschule, Zurich, Switzerland
    FEBS J 275:4850-62. 2008

Research Grants

Detail Information

Publications132 found, 100 shown here

  1. ncbi Genotypic and phenotypic characterization of fusobacteria from Chinese and European patients with inflammatory periodontal diseases
    Rudolf Gmür
    Institute for Oral Biology, Center for Dental, Oral Medicine and Maxillofacial Surgery, University of Zurich, Plattenstrasse 11, CH 8032 Zurich, Switzerland
    Syst Appl Microbiol 29:120-30. 2006
    ..gene sequences resulted in a phylogenetic tree that corresponded well with the current classification of oral fusobacteria into F. periodonticum and several subspecies of F. nucleatum, in spite of much minor genetic variability. F...
  2. ncbi Two distinct proton binding sites in the ATP synthase family
    Christoph von Ballmoos
    Institut fur Mikrobiologie, ETH Zurich, Wolfgang Pauli Strasse 10, CH 8093 Zurich, Switzerland
    Biochemistry 46:11800-9. 2007
    ..The concept of two different binding sites in the ATP synthase family is supported by the ATP hydrolysis pH profiles of the investigated enzymes...
  3. ncbi Structural evidence for a constant c11 ring stoichiometry in the sodium F-ATP synthase
    Thomas Meier
    Institut fur Mikrobiologie, Eidgenossische Technische Hochschule, Zurich, Switzerland
    FEBS J 272:5474-83. 2005
    ..Our results are congruent with a stable c11 ring stoichiometry that seems to not be influenced by the expression level of subunit c in the bacteria...
  4. ncbi Bacterial reduction and persistence after endodontic treatment procedures
    M Sakamoto
    Microbe Division Japan Collection of Microorganisms, RIKEN BioResource Center, Wako, Saitama, Japan
    Oral Microbiol Immunol 22:19-23. 2007
    ....
  5. ncbi Culture-independent analysis of vaginal microflora: the unrecognized association of Atopobium vaginae with bacterial vaginosis
    Hans Verstraelen
    Department of Obstetrics and Gynaecology, Microbiology and Immunology, Ghent University, De Pintelaan 185, 9000 Ghent, Belgium
    Am J Obstet Gynecol 191:1130-2. 2004
    ..Culture-independent analysis of vaginal microflora using 16S rDNA cloning and sequencing of total bacterial communities reveals the gram-positive Atopobium vaginae as a predominant species in disturbed vaginal flora...
  6. ncbi Validation of 16S rDNA sequencing in microdissected bowel biopsies from Crohn's disease patients to assess bacterial flora diversity
    G De Hertogh
    Department of Morphology and Molecular Pathology, University Hospitals KULeuven, Belgium
    J Pathol 209:532-9. 2006
    ..which could be attributed to six different phyla (Proteobacteria, Firmicutes, Bacteroidetes, Actinobacteria, Fusobacteria, and Planctomycetes)...
  7. ncbi Novel ecological niche of Cetobacterium somerae, an anaerobic bacterium in the intestinal tracts of freshwater fish
    C Tsuchiya
    Department of Marine Science and Resources, Nihon University, Kameino, Fujisawa, Kanagawa, Japan
    Lett Appl Microbiol 46:43-8. 2008
    ..This study was conducted to clarify the taxonomic status of Bacteroides type A strains with high vitamin B(12)-producing ability that is widely distributed in the intestinal tracts of freshwater fish...
  8. pmc Torque generation by the Fo motor of the sodium ATPase
    Jianhua Xing
    Department of Molecular Biology, Policy and Management, University of California, Berkeley, California 94720 3112, USA
    Biophys J 87:2148-63. 2004
    ..This work also illustrates how to extract a motor mechanism from dynamical experimental observations in the absence of complete structural information...
  9. ncbi Metabolism of octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine by Clostridium bifermentans strain HAW-1 and several other H2-producing fermentative anaerobic bacteria
    Jian Shen Zhao
    Biotechnology Research Institute, National Research Council of Canada, 6100 Royalmount Avenue, Montreal, Que, Canada H4P 2R2
    FEMS Microbiol Lett 237:65-72. 2004
    Several H2-producing fermentative anaerobic bacteria including Clostridium, Klebsiella and Fusobacteria degraded octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) (36 microM) to formaldehyde (HCHO) and nitrous oxide (N2O) with rates ..
  10. doi Probing the rotor subunit interface of the ATP synthase from Ilyobacter tartaricus
    Denys Pogoryelov
    Institute of Microbiology, Eidgenossische Technische Hochschule, Zurich, Switzerland
    FEBS J 275:4850-62. 2008
    ....
  11. ncbi beta-Lactamase production and susceptibility of US and European anaerobic gram-negative bacilli to beta-lactams and other agents
    M R Jacobs
    Institute of Pathology, Case Western Reserve University, Cleveland, Ohio
    Eur J Clin Microbiol Infect Dis 11:1081-93. 1992
    ..fragilis group, while 95 beta-lactamase producing strains (predominantly Bacteroides fragilis group and fusobacteria) did not show synergy between beta-lactams and clavulanate...
  12. pmc Defining the healthy "core microbiome" of oral microbial communities
    Egija Zaura
    Department of Cariology, Academic Centre for Dentistry Amsterdam ACTA, University of Amsterdam and Free University Amsterdam, The Netherlands
    BMC Microbiol 9:259. 2009
    ..The aim of this study therefore was to define the healthy oral microbiome using recent advances in sequencing technology (454 pyrosequencing)...
  13. ncbi Preterm birth: associations with genital and possibly oral microflora
    G B Hill
    Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC, USA
    Ann Periodontol 3:222-32. 1998
    ..Also, the species and subspecies of fusobacteria identified from amniotic fluid most closely match those reported from healthy and diseased subgingival sites, ..
  14. ncbi Phylogenetic diversity and axial distribution of microbes in the intestinal tract of the polychaete Neanthes glandicincta
    Meng Li
    School of Biological Sciences, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, People s Republic of China
    Microb Ecol 58:892-902. 2009
    ..Methanobacteriaceae, and Methanosarcinales for archaea; and alpha-Proteobacteria, beta-Proteobacteria, Fusobacteria, Clostridia, Chloroflexi, and Planctomycetes for bacteria...
  15. ncbi Fusobacterial brain abscess: a review of five cases and an analysis of possible pathogenesis
    Xiang Y Han
    Department of Laboratory Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Neurosurg 99:693-700. 2003
    ..The cases of five patients with fusobacterial brain abscess are presented. The authors discuss their attempt to determine the pathogenesis...
  16. pmc Unraveling the evolutionary history of the phosphoryl-transfer chain of the phosphoenolpyruvate:phosphotransferase system through phylogenetic analyses and genome context
    Iñaki Comas
    Instituto de Agroquimica y Tecnologia de Alimentos, CSIC, Valencia, Spain
    BMC Evol Biol 8:147. 2008
    ..The aim of this work is to test this hypothesis by studying the evolution of the phosphoryl transfer proteins of the PTS...
  17. ncbi Metronidazole is still the drug of choice for treatment of anaerobic infections
    Sonja Lofmark
    Department of Laboratory Medicine, Division of Clinical Microbiology, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden
    Clin Infect Dis 50:S16-23. 2010
    ..Anaerobic bacterial infections caused by Bacteroides species, fusobacteria, and clostridia respond favorably to metronidazole therapy...
  18. ncbi Co-adhesion and biofilm formation by Fusobacterium nucleatum in response to growth pH
    Peter S Zilm
    Oral Microbiology Laboratory, Dental School, The University of Adelaide, Adelaide, South Australia
    Anaerobe 13:146-52. 2007
    ..attach to epithelial cells, collagen, gingival epithelial cells and other bacterial genera, but not with other Fusobacteria. The development of periodontitis is associated with a rise in pH in the gingival sulcus to around 8...
  19. pmc Identification and characterization of a novel adhesin unique to oral fusobacteria
    Yiping W Han
    Department of Biological Sciences, School of Dental Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106 4905, USA
    J Bacteriol 187:5330-40. 2005
    ..Furthermore, due to its uniqueness to oral Fusobacterium species, fadA may be used as a marker to detect orally related fusobacteria. F. nucleatum isolated from other parts of the body may originate from the oral cavity.
  20. doi Endophytic bacterial diversity in roots of Phragmites australis in constructed Beijing Cuihu Wetland (China)
    Yan Hong Li
    College of Life Science, Capital Normal University, Beijing, China
    FEMS Microbiol Lett 309:84-93. 2010
    ..Other clones belonged to Firmicutes (9.0%), Cytophaga/Flexibacter/Bacteroids (6.6%), Fusobacteria (2.4%), and nearly 3.0% were unidentified bacteria...
  21. ncbi Fusobacterium necrophorum-induced sepsis: an unusual case of Lemierre's syndrome
    P M Kuduvalli
    Department of Anaesthesia and Intensive Care Medicine, Royal Liverpool University Hospital, Liverpool, UK
    Acta Anaesthesiol Scand 49:572-5. 2005
    ..The causative organisms are the anaerobic fusobacteria, most commonly Fusobacterium necrophorum...
  22. pmc Evolutionary relationships of Fusobacterium nucleatum based on phylogenetic analysis and comparative genomics
    Alex Mira
    Evolutionary Genomics Group, Division de Microbiologia, Universidad Miguel Hernandez, Apartado 18, San Juan 03550, Alicante, Spain
    BMC Evol Biol 4:50. 2004
    The phylogenetic position and evolutionary relationships of Fusobacteria remain uncertain...
  23. ncbi Lemierre's syndrome: A systematic review
    Peter D Karkos
    Department of Otolaryngology, Liverpool University Hospitals, United Kingdom
    Laryngoscope 119:1552-9. 2009
    ..It was once called the forgotten disease because of its rarity, but it may not be that uncommon after all. This review aims to provide physicians with an update on the etiology, management, and prognosis of Lemierre's syndrome...
  24. ncbi Isolation of fusobacteria from the oral cavities of malnourished Nigerian children living in agricultural and herding villages
    W A Falkler
    Department of OCBS, School of Dentistry, University of Maryland, Baltimore, MD, USA
    Oral Dis 6:103-5. 2000
    ..necrophorum was part of the oral flora of malnourished children with no noma lesions, a study of the fusobacteria present in the oral cavities of 30 children, 2-6 years of age in Sokoto State, was undertaken...
  25. ncbi Review of the in vitro activity of gemifloxacin against gram-positive and gram-negative anaerobic pathogens
    E J Goldstein
    R M Alden Research Laboratory, Santa Monica UCLA Medical Center, Santa Monica, CA 90494, USA
    J Antimicrob Chemother 45:55-65. 2000
    ..and fusobacteria (Fusobacterium nucleatum, Fusobacterium necrophorum) and moderate but variable potency against Gram-negative ..
  26. pmc Transcriptional regulation of NAD metabolism in bacteria: genomic reconstruction of NiaR (YrxA) regulon
    Dmitry A Rodionov
    Burnham Institute for Medical Research, La Jolla, CA 92037, USA
    Nucleic Acids Res 36:2032-46. 2008
    ..family (re-named here NiaR) are broadly conserved in the Bacillus/Clostridium group and in the deeply branching Fusobacteria and Thermotogales lineages...
  27. ncbi Microbiota around root-form endosseous implants: a review of the literature
    Kees Heydenrijk
    Department of Oral and Maxillofacial Surgery and Maxillofacial Prosthetics, University Hospital Groningen, The Netherlands
    Int J Oral Maxillofac Implants 17:829-38. 2002
    ..involved in peri-implantitis are colonized with large amounts of gram-negative anaerobic bacteria, including Fusobacteria, spirochetes, Bacteroides forsythus, and "black-pigmented bacteria" such as Prevotella intermedia, Prevotella ..
  28. pmc Characterization of the novel Fusobacterium nucleatum plasmid pKH9 and evidence of an addiction system
    Gilad Bachrach
    Institute of Dental Sciences, Hadassah School of Dental Medicine, Hebrew University, Jerusalem, Israel
    Appl Environ Microbiol 70:6957-62. 2004
    ..96-kbp fragment. The pKH9 rep gene is not present in this fragment, suggesting that pKH9 can replicate in fusobacteria independently of the Rep protein. A pKH9-based, compact Escherichia coli-F...
  29. ncbi The antimicrobial effect of a triclosan/copolymer dentifrice on oral microorganisms in vivo
    Daniel H Fine
    Department of Oral Biology, University of Medicine and Dentistry of New Jersey, 185 S Orange Avenue, Newark, NJ 07103, USA
    J Am Dent Assoc 137:1406-13. 2006
    ..The authors compared the in vivo antimicrobial effects on microorganisms from dental plaque, saliva and the tongue in subjects who used a triclosan/copolymer dentifrice and a fluoride dentifrice (control)...
  30. pmc Comparative in vitro activities of GAR-936 against aerobic and anaerobic animal and human bite wound pathogens
    E J Goldstein
    R M Alden Research Laboratory, Santa Monica UCLA Medical Center, Santa Monica, California 90404, USA
    Antimicrob Agents Chemother 44:2747-51. 2000
    ..Porphyromonas spp., Bacteroides tectum, and Peptostreptococcus spp., with an MIC(90) of < or =0.25 microg/ml. Erythromycin- and moxifloxacin-resistant fusobacteria were susceptible to GAR-936, with an MIC(90) of 0.06 microg/ml.
  31. ncbi Factors affecting lysine degradation by ruminal fusobacteria
    James B Russell
    Agricultural Research Service, USDA, Ithaca, New York, USA
    FEMS Microbiol Ecol 56:18-24. 2006
    ..1. The idea that fermentation acids could prevent the enrichment of fusobacteria in vivo was supported by the observation that dietary lysine supplementation did not enhance the lysine ..
  32. ncbi Sequence conservation and distribution of the fusobacterial immunosuppressive protein gene, fipA
    S Hunt Gerardo
    University of California, Los Angeles, School of Dentistry, Department of Periodontology, Los Angeles, CA 90095 1668, USA
    Oral Microbiol Immunol 17:315-20. 2002
    ..However, its distribution and variability among fusobacteria was not reported. Cloned fipA gene sequences from F. nucleatum ssp. polymorphum (ATCC 10953) and F...
  33. doi Characterization of coaggregation of Fusobacterium nucleatum PK1594 with six Porphyromonas gingivalis strains
    Zvi Metzger
    Department of Endodontology, The Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel
    J Endod 35:50-4. 2009
    ..the sugars mentioned (strains HG405 and W50, respectively); and (4) strains that did not coaggregate with the fusobacteria (ATCC33277 and A7436)...
  34. pmc Substrate degradation kinetics, microbial diversity, and current efficiency of microbial fuel cells supplied with marine plankton
    Clare E Reimers
    College of Oceanic and Atmospheric Sciences, Hatfield Marine Science Center, Oregon State University, Newport, OR 97365, USA
    Appl Environ Microbiol 73:7029-40. 2007
    ..allied with Delta-, Epsilon-, and Gammaproteobacteria as well as the Flavobacterium-Cytophaga-Bacteroides and Fusobacteria. Based upon these results, we posit that higher current efficiencies can be achieved by optimizing plankton-fed ..
  35. ncbi [Pyothorax in 26 cats: clinical signs, laboratory results and therapy (2000-2007)]
    Mareike Ottenjann
    Klinik und Poliklinik für kleine Haustiere, Fachbereich Veterinarmedizin, Freie Universitat Berlin
    Berl Munch Tierarztl Wochenschr 121:365-73. 2008
    ..5%) and aerob growing (7.5%) bacteria. Bacterial culture most often yielded Fusobacteria spp., Prevotella spp., Pasteurella spp., Porphyromonas spp. and Bacteroides spp...
  36. doi Phylogenetic analysis of 16S rRNA gene sequences reveals distal gut bacterial diversity in wild wolves (Canis lupus)
    Honghai Zhang
    College of Life Science, Qufu Normal University, Qufu, 273165, China
    Mol Biol Rep 37:4013-22. 2010
    ..9%), Proteobacteria (9.2%), Fusobacteria (9.2%) and Actinobacteria (4.6%). The majority of clones fell within the order Clostridiales (53.8% of OTUs)...
  37. pmc Activity of gatifloxacin compared to those of five other quinolones versus aerobic and anaerobic isolates from skin and soft tissue samples of human and animal bite wound infections
    E J Goldstein
    R M Alden Research Laboratory, Santa Monica UCLA Medical Center, Santa Monica, California 90404, USA
    Antimicrob Agents Chemother 43:1475-9. 1999
    ..Eikenella corrodens, Neisseria weaveri, Weeksella zoohelcum, staphylococci, and streptococci. Fusobacteria were sometimes resistant. Gatifloxacin MICs at which 90% of the isolates were inhibited were 0...
  38. pmc Bacterial biota in the human distal esophagus
    Zhiheng Pei
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    Proc Natl Acad Sci U S A 101:4250-5. 2004
    ..Members of six phyla, Firmicutes, Bacteroides, Actinobacteria, Proteobacteria, Fusobacteria, and TM7, were represented...
  39. ncbi Individual architecture of subgingival microflora in chronic periodontitis
    Minoru Sasamoto
    Department of Periodontology, Fukuoka Dental College, Fukuoka, Japan
    J Int Acad Periodontol 11:138-46. 2009
    ..The purpose of this study was to determine the ecological architecture of the subgingival microflora among chronic periodontitis patients and their individual differences based on phylotype analyses...
  40. pmc Spatial organisation of microbiota in quiescent adenoiditis and tonsillitis
    A Swidsinski
    Medizinische Klinik, Charité Humboldt Universität, CCM, Molekular genetisches Labor für polymikrobielle Infektionen und bakterielle Biofilme, Berlin, Germany
    J Clin Pathol 60:253-60. 2007
    ..The reasons for recurrent adenotonsillitis are poorly understood...
  41. ncbi Survey on 'lumpy jaw' on deer farms in western Canada: prevalence and distribution, and identification of associated factors
    R C Mainar-Jaime
    Department of Veterinary Microbiology, Western College of Veterinary Medicine, University of Saskatchewan 52 Campus Drive, Saskatoon, SK, S7N 5B4, Canada
    N Z Vet J 55:30-9. 2007
    ....
  42. ncbi Molecular-phylogenetic characterization of microbial communities imbalances in the small intestine of dogs with inflammatory bowel disease
    Panagiotis G Xenoulis
    Gastrointestinal Laboratory, Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A and M University, TX 77843 4474, USA
    FEMS Microbiol Ecol 66:579-89. 2008
    ..4%), Proteobacteria (28.4%), Bacteroidetes (7.0%), Spirochaetes (5.2%), Fusobacteria (3.4%), Actinobacteria (1.1%), and Incertae sedis (1.5%)...
  43. pmc Molecular analysis of the bacterial microbiota in the human stomach
    Elisabeth M Bik
    Department of Microbiology and Immunology, Stanford University School of Medicine, Fairchild Science Building, 299 Campus Drive, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 103:732-7. 2006
    ..The majority of sequences were assigned to the Proteobacteria, Firmicutes, Actinobacteria, Bacteroidetes, and Fusobacteria phyla...
  44. doi Aggregatibacter actinomycetemcomitans serotype f O-polysaccharide mediates coaggregation with Fusobacterium nucleatum
    D Rupani
    Department of Oral Biology, New Jersey Dental School, Newark, NJ, USA
    Oral Microbiol Immunol 23:127-30. 2008
    ..Intergeneric bacterial coaggregation may play an important role in plaque development...
  45. pmc Newly cultured bacteria with broad diversity isolated from eight-week continuous culture enrichments of cow feces on complex polysaccharides
    Cherie J Ziemer
    USDA, Agricultural Research Service, National Laboratory for Agriculture and the Environment, Ames, Iowa, USA
    Appl Environ Microbiol 80:574-85. 2014
    ..9%), Bacteroidetes (30.9%), Proteobacteria (11.1%), Actinobacteria (3.5%), Synergistetes (1.5%), and Fusobacteria (1.1%). The majority of bacterial isolates had <98...
  46. doi Laboratory maintenance of fusobacteria
    Yiping W Han
    Case Western Reserve University, Cleveland, Ohio, USA
    Curr Protoc Microbiol . 2006
    This unit describes routine laboratory handling of fusobacteria. Different media that can be used to grow or enrich Fusobacterium nucleatum and other species of this genus are described...
  47. ncbi Recent concepts in plaque formation
    J P Bernimoulin
    Department of Periodontology and Synoptic Dentistry, Humboldt University, Berlin, Germany
    J Clin Periodontol 30:7-9. 2003
    ..be active against a wide range of Gram-positive and Gram-negative bacterial species, including streptococci and fusobacteria. Ideally, an effective agent would also penetrate the plaque biofilm...
  48. ncbi Succinate accumulation in pig large intestine during antibiotic-associated diarrhea and the constitution of succinate-producing flora
    Takamitsu Tsukahara
    Laboratory of Animal Science, Kyoto Prefectural University, Japan
    J Gen Appl Microbiol 48:143-54. 2002
    ..In contrast to antibiotic-associated diarrhea pigs, bacteria belonging to Bacteroidaceae, Fusobacteria, and Enterobacteriaceae were detected as succinate producers in a non-treated pig...
  49. ncbi Retroids in archaea: phylogeny and lateral origins
    Joshua S Rest
    Department of Ecology and Evolutionary Biology and Museum of Zoology, University of Michigan, Ann Arbor, USA
    Mol Biol Evol 20:1134-42. 2003
    ..phylogenetic analysis also identifies several novel retrons from GenBank in the bacterial groups Firmicutes, Fusobacteria, Cyanobacteria and beta-Proteobacteria, as well as in M. acetivorans...
  50. pmc Post-weaning diet affects faecal microbial composition but not selected adipose gene expression in the cat (Felis catus)
    Emma N Bermingham
    Food Nutrition and Health, AgResearch Grasslands, Palmerston North, New Zealand
    PLoS ONE 8:e80992. 2013
    ..8% vs 0.2% of total reads), and decreased (P<0.05) abundance of Fusobacteria (1.6% vs 18...
  51. pmc Culture-independent characterization of the digestive-tract microbiota of the medicinal leech reveals a tripartite symbiosis
    Paul L Worthen
    Department of Molecular and Cell Biology, University of Connecticut, 91 N Eagleville Rd, Unit 3125, Storrs, CT 06269 3125, USA
    Appl Environ Microbiol 72:4775-81. 2006
    ..and additional symbionts were detected, including members of the alpha-, gamma-, and delta-Proteobacteria, Fusobacteria, Firmicutes, and Bacteroidetes. The relative abundances of the clones suggested that A...
  52. pmc Fecal microbiota and metabolome of children with autism and pervasive developmental disorder not otherwise specified
    Maria de Angelis
    Department of Soil, Plant and Food Sciences, University of Bari Aldo Moro, Bari, Italy
    PLoS ONE 8:e76993. 2013
    ..The main bacterial phyla (Firmicutes, Bacteroidetes, Fusobacteria and Verrucomicrobia) significantly (P<0.05) changed among the three groups of children...
  53. doi Microbial community changes in hydraulic fracturing fluids and produced water from shale gas extraction
    Arvind Murali Mohan
    National Energy Technology Laboratory, Pittsburgh, Pennsylvania 15236, United States
    Environ Sci Technol 47:13141-50. 2013
    ..affiliated with the classes Clostridia, Bacilli, Gammaproteobacteria, Epsilonproteobacteria, Bacteroidia, and Fusobacteria. Produced water collected at the last time point (day 187) consisted almost entirely of sequences similar to ..
  54. ncbi Evaluation of the in vitro activity of ertapenem and nine other comparator agents against 337 anaerobic bacteria
    J Behra-Miellet
    Faculte de Pharmacie, 3 rue du Professeur Laguesse, BP83, 59006 Lille Cedex, France
    Int J Antimicrob Agents 28:25-35. 2006
    ..5, 0.25, 0.06 and <or=0.03mg/L for the Bacteroides fragilis group, Prevotella spp., fusobacteria and Gram-positive cocci, respectively. Overall resistance rates were 2.1%, 51.3%, 2.4%, 1.2%, 1.5%, 7.1%, 0...
  55. ncbi Activity of linezolid against anaerobic bacteria
    Josette Behra-Miellet
    Faculte de Pharmacie, University of Lille II, 3 rue du Professeur Laguesse, BP83, 59006 Lille Cedex, France
    Int J Antimicrob Agents 22:28-34. 2003
    ..LZD MIC(50) was 4 mg/l for prevotella and 1 mg/l for fusobacteria. LZD MICs were <1 mg/l for porphyromonas and veillonellae and </=4 mg/l for all Gram-positive anaerobes...
  56. doi Age-related differences revealed in Australian fur seal Arctocephalus pusillus doriferus gut microbiota
    Stuart C Smith
    School of Exercise and Nutrition Sciences, Deakin University, Burwood, Vic, Australia Molecular and Medical Research, Deakin University, Burwood, Vic, Australia
    FEMS Microbiol Ecol 86:246-55. 2013
    ..in the composition of Firmicutes, Bacteroidetes, Actinobacteria, Proteobacteria, Verrucomicrobia and Fusobacteria at all ages...
  57. ncbi Summary of: Oral health, dental prophylaxis and catheter related bloodstream infections in home parenteral nutrition patients: results of a UK survey and cohort study
    D Wray
    Belfast School of Dentistry Northern Ireland
    Br Dent J 212:86-7. 2012
    ..Clinical guideline 64 is widely recognised and observed. There is a lack of consistent guidance for other patient groups viewed at risk from procedural bacteraemia...
  58. doi Current state of knowledge: the canine gastrointestinal microbiome
    Seema Hooda
    Department of Animal Sciences, University of Illinois, 1207 West Gregory Drive, Urbana, IL 61801, USA
    Anim Health Res Rev 13:78-88. 2012
    ..Predominant phyla include Firmicutes, Bacteroidetes, Fusobacteria, Proteobacteria, and Actinobacteria...
  59. ncbi Characterization of cecal microbiota of the emu (Dromaius novaehollandiae)
    Darin C Bennett
    Avian Research Centre, Faculty of Land and Food Systems, University of British Columbia, 2357 Main Mall, Vancouver, British Columbia V6T 1Z4, Canada
    Vet Microbiol 166:304-10. 2013
    ..bacterial phyla were Bacteroidetes (≈ 57% of total classified diversity), Proteobacteria (≈ 24%), Fusobacteria (≈ 11.3%), and Firmicutes (≈ 7%)...
  60. pmc Immune status, antibiotic medication and pH are associated with changes in the stomach fluid microbiota
    Erik C von Rosenvinge
    Division of Gastroenterology and Hepatology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    ISME J 7:1354-66. 2013
    ..stomach fluid samples are dominated by the phyla Firmicutes, Bacteroidetes, Actinobacteria, Proteobacteria and Fusobacteria (>99% of sequence reads), the transcriptionally active microbiota shows significant reduction in ..
  61. pmc Structural study on the architecture of the bacterial ATP synthase Fo motor
    Jonna K Hakulinen
    Department of Structural Biology, Max Planck Institute of Biophysics, 60438 Frankfurt Main, Germany
    Proc Natl Acad Sci U S A 109:E2050-6. 2012
    ..The location and distances of the stator helices impose spatial restrictions on the bacterial F(o) complex...
  62. pmc Comparison of the fecal microbiota of healthy horses and horses with colitis by high throughput sequencing of the V3-V5 region of the 16S rRNA gene
    Marcio C Costa
    Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada
    PLoS ONE 7:e41484. 2012
    ..higher relative abundance of Actinobacteria and Spirochaetes while horses with colitis had significantly more Fusobacteria. Members of the Clostridia class were more abundant in healthy horses...
  63. doi Broad diversity and newly cultured bacterial isolates from enrichment of pig feces on complex polysaccharides
    Cherie J Ziemer
    USDA, Agricultural Research Service, National Laboratory for Agriculture and the Environment, Ames, IA 50010, USA
    Microb Ecol 66:448-61. 2013
    ..phyla were represented in the bacterial isolates: Firmicutes (242), Bacteroidetes (185), Proteobacteria (65), Fusobacteria (55), Actinobacteria (23), and Synergistetes (5)...
  64. pmc The relation between oral Candida load and bacterial microbiome profiles in Dutch older adults
    Eefje A Kraneveld
    Department of Preventive Dentistry, Academic Centre for Dentistry Amsterdam, University of Amsterdam, Amsterdam, The Netherlands
    PLoS ONE 7:e42770. 2012
    ..001). Increase in the Candida load correlated positively with class Bacilli, and negatively with class Fusobacteria, Flavobacteria, and Bacteroidia...
  65. pmc Interspecific variations in the gastrointestinal microbiota in penguins
    Meagan L Dewar
    School of Exercise and Nutritional Sciences, Deakin University, Burwood, Australia
    Microbiologyopen 2:195-204. 2013
    ..A total of 13 phyla were identified with Firmicutes, Bacteroidetes, Proteobacteria, and Fusobacteria dominating the composition; however, there were major differences in the relative abundance of the phyla...
  66. doi Faecal microbiota in lean and obese dogs
    Stefanie Handl
    Institute of Animal Nutrition and Functional Plant Compounds, University of Veterinary Medicine Vienna, Vienna, Austria
    FEMS Microbiol Ecol 84:332-43. 2013
    ..Firmicutes, Fusobacteria and Actinobacteria were the predominant bacterial phyla...
  67. pmc The lung microbiome in moderate and severe chronic obstructive pulmonary disease
    Alexa A Pragman
    Department of Medicine, University of Minnesota, Minneapolis, MN, USA
    PLoS ONE 7:e47305. 2012
    ..However, samples did cluster based on the use of inhaled corticosteroids and inhaled bronchodilators. Metastats analyses demonstrated an increased abundance of several oral bacteria in COPD samples...
  68. pmc Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma
    Mauro Castellarin
    BC Cancer Agency, Michael Smith Genome Sciences Centre, Vancouver, British Columbia V5Z 1L3, Canada
    Genome Res 22:299-306. 2012
    ..b>Fusobacteria are rare constituents of the fecal microbiota, but have been cultured previously from biopsies of inflamed gut ..
  69. doi A close relationship between primary nucleotides sequence structure and the composition of functional genes in the genome of prokaryotes
    Juan A L Garcia
    Department of Continental Ecology Biogeodynamics and Biodiversity Group, Centre d Estudis Avançats de Blanes, CEAB CSIC, E 17300 Blanes, Girona, Spain
    Mol Phylogenet Evol 61:650-8. 2011
    ..weakly (AT) bonded nucleotides. Interestingly, the phyla Aquificae, Fusobacteria, Dictyoglomi, Nitrospirae, and Thermotogae were closer to archaea than to their bacterial counterparts...
  70. doi Metagenomic analysis of the uterine bacterial microbiota in healthy and metritic postpartum dairy cows
    T M A Santos
    Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    J Dairy Sci 94:291-302. 2011
    ..Sequences were assigned to 5 major groups (Gammaproteobacteria, Firmicutes, Fusobacteria, Bacteroidetes, and Tenericutes) and to uncultured bacteria...
  71. doi Bacteria in bovine semen can increase sperm DNA fragmentation rates: a kinetic experimental approach
    C González-Marín
    Unidad de Genetica, Departamento de Biologia, Universidad Autonoma de Madrid, C Darwin no 2, 28049 Madrid, Spain
    Anim Reprod Sci 123:139-48. 2011
    ..Different species within the phyla Bacteroidetes, Firmicutes, Proteobacteria, Cyanobacteria, Fusobacteria and Actinobacteria were identified...
  72. doi Companion animals symposium: microbes and gastrointestinal health of dogs and cats
    J S Suchodolski
    Gastrointestinal Laboratory, Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A and M University, College Station, TX 77843 4474, USA
    J Anim Sci 89:1520-30. 2011
    ..More than 10 bacterial phyla have been identified, with Firmicutes, Bacteroidetes, Proteobacteria, Fusobacteria, and Actinobacteria constituting more than 99% of all gut microbiota...
  73. pmc Community and gene composition of a human dental plaque microbiota obtained by metagenomic sequencing
    G Xie
    Oralgen Database, Genome Science Group, Bioscience Division, Los Alamos National Laboratory, Los Alamos, NM 87545, USA
    Mol Oral Microbiol 25:391-405. 2010
    ..Furthermore, ~2.8% of the total predicted genes coded for proteins involved in resistance to antibiotics and toxic compounds, suggesting that the oral cavity is an important reservoir for antimicrobial resistance...
  74. doi The p-type ATPase superfamily
    Henry Chan
    Division of Biological Sciences, University of California at San Diego, La Jolla, CA, USA
    J Mol Microbiol Biotechnol 19:5-104. 2010
    ..In some bacterial phyla (e.g. Bacteroidetes, Flavobacteria and Fusobacteria), ATPase gene gain and loss as well as horizontal transfer occurred seldom in contrast to most other bacterial ..
  75. doi Distinct microbiome in pouchitis compared to healthy pouches in ulcerative colitis and familial adenomatous polyposis
    Garrett C Zella
    Division of Pediatric Gastroenterology, Department of Pediatrics, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Inflamm Bowel Dis 17:1092-100. 2011
    ..Our aim was to compare mucosal and luminal flora in patients with UC-associated pouchitis (UCP), healthy UC pouches (HUC), and healthy FAP pouches (FAP)...
  76. ncbi Effects of the antibiotic growth promoters flavomycin and florfenicol on the autochthonous intestinal microbiota of hybrid tilapia (Oreochromis niloticus ♀ × O. aureus ♂)
    Suxu He
    Key Laboratory for Feed Biotechnology of the Ministry of Agriculture, Feed Research Institute, Chinese Academy of Agricultural Sciences, 100081 Beijing, People s Republic of China
    Arch Microbiol 192:985-94. 2010
    ..Dietary flavomycin only reduced the OTU intensity of one phylotype, identified as a member of the phylum Fusobacteria. The antibiotic combination only reduced the phylotypes EU563242 and EU563262...
  77. doi Inference of the phylogenetic position of the phylum Deferribacteres from gene order comparison
    Takashi Kunisawa
    Department of Applied Biological Sciences, Science University of Tokyo, Noda, Japan
    Antonie Van Leeuwenhoek 99:417-22. 2011
    ..group of phyla, Synergistetes, Firmicutes, Actinobacteria, Thermotogae, Chloroflexi and Deinococcus-Thermus, Fusobacteria, shares alternative sets of gene arrangements, suggesting that the Deferribacteres is classified in the former ..
  78. ncbi [Changes of bacterial community structure on reusing domestic sewage of Daoxianghujing Hotel to landscape water]
    Jing nan Zhu
    College of Life Science, Capital Normal University, Beijing 100048, China
    Huan Jing Ke Xue 31:1299-306. 2010
    ..In addition, both the CFB phylum, Fusobacteria, gamma Proteobacteria and Firmicutes were also reached to 9%-15%...
  79. ncbi Bacterial colonization during de novo plaque formation
    Per Ramberg
    Department of Periodontology, Institute of Odontology, Goteborg University, Sweden
    J Clin Periodontol 30:990-5. 2003
    ..To determine microbial changes that occur during plaque formation in a dentition free of gingival inflammation...
  80. doi Ecological characterisation of the colonic microbiota in arctic and sub-arctic seals
    Trine Glad
    Department of Pharmacy, University of Tromsø, 9037 Tromsø, Norway
    Microb Ecol 60:320-30. 2010
    ..7% Bacteroidetes, 41.5% Firmicutes, 4.5% Proteobacteria and 1.0% Fusobacteria. Thirty (77%) of the 39 phylotypes identified were novel, showing <97% sequence similarity to their nearest ..
  81. pmc Phylogenetic characterization of fecal microbial communities of dogs fed diets with or without supplemental dietary fiber using 454 pyrosequencing
    Ingmar S Middelbos
    Department of Animal Sciences, University of Illinois, Urbana, Illinois, United States of America
    PLoS ONE 5:e9768. 2010
    ..This work aimed to use 16S rDNA tag pyrosequencing to phylogenetically characterize hindgut microbiome in dogs and determine how consumption of dietary fiber affects community structure...
  82. ncbi Relationship between periodontal pocket sulfide levels and subgingival species
    G Torresyap
    Department of Periodontology, The Forsyth Institute, Boston, MA 02115, USA
    J Clin Periodontol 30:1003-10. 2003
    ..This investigation examined the relationship between levels of sulfide and subgingival bacterial species in the same periodontal pockets...
  83. pmc Molecular characterization of the microbial flora residing at the apical portion of infected root canals of human teeth
    Nadia Chugal
    Section of Endodontics, UCLA School of Dentistry, UCLA School of Medicine, Los Angeles, California 90095 1668, USA
    J Endod 37:1359-64. 2011
    ..This study investigated the bacterial communities residing in the apical portion of human teeth with apical periodontitis in primary and secondary infections by using a culture-independent molecular biology approach...
  84. ncbi In vitro activity of gemifloxacin compared to seven other oral antimicrobial agents against aerobic and anaerobic pathogens isolated from antral sinus puncture specimens from patients with sinusitis
    Ellie J C Goldstein
    R M Alden Research Laboratory, Santa Monica UCLA Medical Center, Santa Monica, CA 90404, USA
    Diagn Microbiol Infect Dis 42:113-8. 2002
    ..All fusobacteria were susceptible to < or =0.25 ug/mL of gemifloxacin...
  85. pmc Lactobacilli are prominent in the initial stages of polymicrobial infection of dental pulp
    Mangala A Nadkarni
    Institute of Dental Research, Westmead Centre for Oral Health and Westmead Millennium Institute, P O Box 533, Wentworthville, NSW 2145, Australia
    J Clin Microbiol 48:1732-40. 2010
    ..from the phylum Actinobacteria; and Prevotellaceae from the phylum Bacteroidetes, as well as fusobacteria. The phases of infection of vital pulp tissue by dentin microorganisms remain obscure...
  86. ncbi The in-vitro activity of roxithromycin, a new macrolide antibiotic, in comparison with that of erythromycin
    A King
    Microbiology Department, United Medical School of Guy s Hospital, London, England
    Drugs Exp Clin Res 13:563-6. 1987
    ..Most anaerobic bacteria were sensitive although Bacteroides fragilis, fusobacteria and some strains of some clostridial species were moderately resistant...
  87. ncbi Beta-lactam resistance in anaerobic bacteria: a review
    M Hedberg
    Department of Immunology, Microbiology, Pathology and Infectious Diseases, Huddinge University Hospital, Stockholm, Sweden
    J Chemother 8:3-16. 1996
    ..Beta-lactam resistance and beta-lactamase production have also been detected in some species of clostridia, fusobacteria, Prevotella, Porphyromonas and in some other anaerobic bacteria.
  88. ncbi Ecological effect of gatifloxacin on the normal human intestinal microflora
    C Edlund
    Department of Immunology, Microbiology, Pathology and Infectious Diseases, Karolinska Institute, Huddinge University Hospital, Stockholm, Sweden
    J Chemother 11:50-3. 1999
    ..In the anaerobic microflora the numbers of clostridia and fusobacteria decreased significantly during the administration period while no other major changes occurred...
  89. pmc Linezolid activity compared to those of selected macrolides and other agents against aerobic and anaerobic pathogens isolated from soft tissue bite infections in humans
    E J Goldstein
    R M Alden Research Laboratory, Santa Monica UCLA Medical Center, Santa Monica, California 90404, USA
    Antimicrob Agents Chemother 43:1469-74. 1999
    ..The MIC was </=2 microg/ml for staphylococci, streptococci, EF-4b, Weeksella zoohelcum, Fusobacterium nucleatum, other fusobacteria, Porphyromonas spp., Prevotella spp., peptostreptococci, and almost all Bacteroides tectum isolates.
  90. pmc In vitro activity of gemifloxacin (SB 265805) against anaerobes
    E J Goldstein
    R M Alden Research Laboratory, Santa Monica University of California at Los Angeles Medical Center, Santa Monica, California 90404, USA
    Antimicrob Agents Chemother 43:2231-5. 1999
    ..Gemifloxacin mesylate (SB 265805) was 1 to 4 dilutions more active than trovafloxacin against fusobacteria and peptostreptococci, and the two drugs were equivalent against clostridia and P. asaccharolytica...
  91. ncbi Comparative effects of moxifloxacin and clarithromycin on the normal intestinal microflora
    C Edlund
    Krolinska Institute, Hudinge University Hospital, Sweden
    Scand J Infect Dis 32:81-5. 2000
    ..No impact on peptostreptococci, lactobacilli, Veillonella, Bacteroides or fusobacteria was observed, while bifidobacteria and clostridia decreased during moxifloxacin administration...
  92. ncbi Effects of Streptococcus crista and human saliva on the viability of Fusobacterium nucleatum ATCC 10953
    J D Rudney
    Department of Oral Science, School of Dentistry, University of Minnesota, 17 252 Moos Tower, 515 Delaware St SE, Minneapolis, MN 55455, USA
    Arch Oral Biol 45:667-74. 2000
    ..For co-aggregate suspensions, there was no difference in the viability of fusobacteria that were or were not in direct contact with Strep. crista...
  93. ncbi Oral microbial communities: biofilms, interactions, and genetic systems
    P E Kolenbrander
    Oral Infection and Immunity Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892, USA
    Annu Rev Microbiol 54:413-37. 2000
    ..b>Fusobacteria play a central role as physical bridges that mediate coaggregation of cells and as physiological bridges that ..
  94. pmc In vitro activities of ABT-773, a new ketolide, against aerobic and anaerobic pathogens isolated from antral sinus puncture specimens from patients with sinusitis
    E J Goldstein
    R M Alden Research Laboratory Santa Monica UCLA Medical Center, Santa Monica, California 90404, USA
    Antimicrob Agents Chemother 45:2363-7. 2001
    ..125 microg/ml. Among the anaerobes tested, only fusobacteria (45%) required > or =4 microg of ABT-773/ml for inhibition...
  95. ncbi Ilyobacter insuetus sp. nov., a fermentative bacterium specialized in the degradation of hydroaromatic compounds
    Andreas Brune
    Lehrstuhl für Mikrobielle Ökologie, Fachbereich Biologie, Universitat Konstanz, Germany
    Int J Syst Evol Microbiol 52:429-32. 2002
    ..Comparative 16S and 23S rDNA sequence analyses placed strain VenChi2T in the fusobacteria phylum, with the closest relatives among species of the genera Ilyobacter and Propionigenium...
  96. ncbi Critical issues in bacterial phylogeny
    Radhey S Gupta
    Department of Biochemistry, McMaster University, Hamilton, Ontario, Canada L8N 3Z5
    Theor Popul Biol 61:423-34. 2002
    ..common ancestor in the following order: Low G+C Gram-positive ==> High G+C Gram-positive ==> Clostridium-Fusobacteria-Thermotoga ==> Deinococcus-Thermus-Green nonsulfur bacteria ==> Cyanobacteria ==> Spirochetes ==> ..
  97. ncbi Limited selection of sodium channel blocking toxin-producing bacteria from paralytic shellfish toxin-contaminated mussels (Aulacomya ater)
    Monica Vasquez
    Laboratorio de Biotecnologia, INTA Universidad de Chile, Santiago, Chile
    Res Microbiol 153:333-8. 2002
    ..clustered with species of the y-Proteobacteria subclass, the Cytophaga-Flexibacter-Bacteroides (CFB), the Fusobacteria and the Firmicutes phyla...
  98. ncbi Severe Fusobacteria infections (Lemierre syndrome) in two boys
    Lars Klinge
    Department of Paediatrics and Paediatric Nephrology, University Children s Hospital Essen, Hufelandstrasse 55, 45122 Essen, Germany
    Eur J Pediatr 161:616-8. 2002
    ..Belonging to the resident flora of the oropharyngeal region, Fusobacteria are known to cause local infections; from here they may extend to other sites via the bloodstream or are ..
  99. pmc Bacterial alpha2-macroglobulins: colonization factors acquired by horizontal gene transfer from the metazoan genome?
    Aidan Budd
    European Molecular Biology Laboratory, 69012 Heidelberg, Germany
    Genome Biol 5:R38. 2004
    ..The protease inhibitor alpha2-macroglobulin provides a major metazoan defense against invasive bacteria, trapping attacking proteases required by parasites for successful invasion...
  100. ncbi Dehydration of (R)-2-hydroxyacyl-CoA to enoyl-CoA in the fermentation of alpha-amino acids by anaerobic bacteria
    Jihoe Kim
    Laboratorium für Mikrobiologie, Fachbereich Biologie, Philipps Unversität, Karl von Frisch Strasse, D 35032 Marburg, Germany
    FEMS Microbiol Rev 28:455-68. 2004
    Several clostridia and fusobacteria ferment alpha-amino acids via (R)-2-hydroxyacyl-CoA, which is dehydrated to enoyl-CoA by syn-elimination...
  101. pmc The Fusobacterium nucleatum outer membrane protein RadD is an arginine-inhibitable adhesin required for inter-species adherence and the structured architecture of multispecies biofilm
    Christopher W Kaplan
    School of Dentistry, UCLA, Los Angeles, CA, USA
    Mol Microbiol 71:35-47. 2009
    ..distinguishing feature is suggested to play an important role in oral biofilm formation and pathogenesis, with fusobacteria proposed to serve as central 'bridging organisms' in the architecture of the oral biofilm bringing together ..

Research Grants52

  1. SOURCES OF TOXINS FROM HUMAN DENTAL PLAQUE
    Martin Levine; Fiscal Year: 1980
    ..ways of idenifying the plaque inhibitors, extracellular products of Streptococci, Actinomyces, Bacteroides and Fusobacteria, which have been closely associated with existing established gingivitis or severe periodontitis, will be ..
  2. Low pH-mediated membrane biosynthesis in S. mutans.
    ROBERT QUIVEY; Fiscal Year: 2007
    ..The FabM enzyme is presently identified in only 3 bacterial genera: the Streptococci. Staphylococci, and Fusobacteria. Thus, knowledge about the role of the enzyme in S. mutans will shed light on other important human pathogens...
  3. Low pH-mediated membrane biosynthesis in S. mutans.
    Robert G Quivey; Fiscal Year: 2010
    ..The FabM enzyme is presently identified in only 3 bacterial genera: the Streptococci. Staphylococci, and Fusobacteria. Thus, knowledge about the role of the enzyme in S. mutans will shed light on other important human pathogens...
  4. Low pH-mediated membrane biosynthesis in S. mutans.
    ROBERT QUIVEY; Fiscal Year: 2006
    ..The FabM enzyme is presently identified in only 3 bacterial genera: the Streptococci. Staphylococci, and Fusobacteria. Thus, knowledge about the role of the enzyme in S. mutans will shed light on other important human pathogens...
  5. Low pH-mediated membrane biosynthesis in S. mutans.
    ROBERT QUIVEY; Fiscal Year: 2009
    ..The FabM enzyme is presently identified in only 3 bacterial genera: the Streptococci. Staphylococci, and Fusobacteria. Thus, knowledge about the role of the enzyme in S. mutans will shed light on other important human pathogens...
  6. MICROBIOLOGIC STUDIES OF HUMAN ORAL STREPTOCOCCI
    JOSEPH DIRIENZO; Fiscal Year: 2001
    ..Nucleatum. Microscopic studies have shown that the binding of S. crista to the fusobacteria occurs through hair-like processes, called fimbriae, are the adhesins that mediate corncob formation...
  7. MICROBIOLOGIC STUDIES OF HUMAN ORAL STREPTOCOCCI
    JOSEPH DIRIENZO; Fiscal Year: 1999
    ..Nucleatum. Microscopic studies have shown that the binding of S. crista to the fusobacteria occurs through hair-like processes, called fimbriae, are the adhesins that mediate corncob formation...
  8. MICROBIOLOGIC STUDIES OF HUMAN ORAL STREPTOCOCCI
    JOSEPH DIRIENZO; Fiscal Year: 2000
    ..Nucleatum. Microscopic studies have shown that the binding of S. crista to the fusobacteria occurs through hair-like processes, called fimbriae, are the adhesins that mediate corncob formation...
  9. Murine Model of Sexually Transmitted Disease-enhanced HIV Transmission
    Gregory Spear; Fiscal Year: 2007
    ..This revised application includes new data that shows infection of Tg mice by HIV can be detected both in vitro and in vivo thus indicating the feasibility of the proposed experiments. [unreadable] [unreadable] [unreadable]..
  10. ANTI-HIV-1 ACTIVITY OF MANNAN-BINDING LECTIN
    Gregory Spear; Fiscal Year: 2001
    ..3. Utilize inhibitors of glycosylation to enhance biological effects of MBL. Exarnine the interaction of MBL with anti-viral antibodies in mediating anti-viral effects. Deterrnine the interaction of HIV-1 with MBL in vivo. ..
  11. ANTI-HIV-1 ACTIVITY OF MANNAN-BINDING LECTIN
    Gregory Spear; Fiscal Year: 2000
    ..3. Utilize inhibitors of glycosylation to enhance biological effects of MBL. Exarnine the interaction of MBL with anti-viral antibodies in mediating anti-viral effects. Deterrnine the interaction of HIV-1 with MBL in vivo. ..
  12. ANTI-HIV-1 ACTIVITY OF MANNAN-BINDING LECTIN
    Gregory Spear; Fiscal Year: 2003
    ..3. Utilize inhibitors of glycosylation to enhance biological effects of MBL. Exarnine the interaction of MBL with anti-viral antibodies in mediating anti-viral effects. Deterrnine the interaction of HIV-1 with MBL in vivo. ..
  13. ANTI-HIV-1 ACTIVITY OF MANNAN-BINDING LECTIN
    Gregory Spear; Fiscal Year: 2002
    ..3. Utilize inhibitors of glycosylation to enhance biological effects of MBL. Exarnine the interaction of MBL with anti-viral antibodies in mediating anti-viral effects. Deterrnine the interaction of HIV-1 with MBL in vivo. ..
  14. Etiology & pathogenesis of chronic tonsillar hypertrophy
    Zhiheng Pei; Fiscal Year: 2007
    ..Later, we will develop a simple ELISA capable of screening a large number of patients for tonsillar antibodies to the MC-species. Addressing the three aims will provide evidence to examine the hypothesis of a bacterial etiology of CTH. ..
  15. A Foundation for the Oral Microbiome and Metagenome
    Floyd Dewhirst; Fiscal Year: 2007
    ..Knowing more about these many bacteria will allow scientists to develop better methods for treating and preventing oral diseases. [unreadable] [unreadable] [unreadable]..
  16. Attachment of Oral Actinobacillus to Epithelium
    Daniel Fine; Fiscal Year: 2006
    ..The longterm goal of this application is to use this information to identify targets for therapeutic agents that can interfere with attachment of Aa to oral tissues and thus prevent colonization leading to LAP. [unreadable] [unreadable]..
  17. Etiology & pathogenesis of chronic tonsillar hypertrophy
    Zhiheng Pei; Fiscal Year: 2006
    ..Later, we will develop a simple ELISA capable of screening a large number of patients for tonsillar antibodies to the MC-species. Addressing the three aims will provide evidence to examine the hypothesis of a bacterial etiology of CTH. ..
  18. Etiology & pathogenesis of chronic tonsillar hypertrophy
    Zhiheng Pei; Fiscal Year: 2005
    ..Later, we will develop a simple ELISA capable of screening a large number of patients for tonsillar antibodies to the MC-species. Addressing the three aims will provide evidence to examine the hypothesis of a bacterial etiology of CTH. ..
  19. Attachment of Oral Actinobacillus to Epithelium
    Daniel Fine; Fiscal Year: 2007
    ..The longterm goal of this application is to use this information to identify targets for therapeutic agents that can interfere with attachment of Aa to oral tissues and thus prevent colonization leading to LAP. [unreadable] [unreadable]..
  20. Localized Aggressive Periodontitis: Microbial & Host Markers for Susceptibility
    Daniel Fine; Fiscal Year: 2009
    ....
  21. Localized Aggressive Periodontitis: Microbial & Host Markers for Susceptibility
    Daniel H Fine; Fiscal Year: 2010
    ....
  22. Localized Aggressive Periodontitis: Microbial & Host Markers for Susceptibility
    Daniel Fine; Fiscal Year: 2009
    ....
  23. Etiology & pathogenesis of chronic tonsillar hypertrophy
    Zhiheng Pei; Fiscal Year: 2009
    ..Later, we will develop a simple ELISA capable of screening a large number of patients for tonsillar antibodies to the MC-species. Addressing the three aims will provide evidence to examine the hypothesis of a bacterial etiology of CTH. ..
  24. Attachment of Oral Actinobacillus to Epithelium
    Daniel Fine; Fiscal Year: 2008
    ..The longterm goal of this application is to use this information to identify targets for therapeutic agents that can interfere with attachment of Aa to oral tissues and thus prevent colonization leading to LAP. [unreadable] [unreadable]..
  25. Localized Aggressive Periodontitis: Microbial & Host Markers for Susceptibility
    Daniel Fine; Fiscal Year: 2008
    ....
  26. A Foundation for the Oral Microbiome and Metagenome
    Floyd Dewhirst; Fiscal Year: 2008
    ..Knowing more about these many bacteria will allow scientists to develop better methods for treating and preventing oral diseases. ..
  27. Etiology & pathogenesis of chronic tonsillar hypertrophy
    Zhiheng Pei; Fiscal Year: 2008
    ..Later, we will develop a simple ELISA capable of screening a large number of patients for tonsillar antibodies to the MC-species. Addressing the three aims will provide evidence to examine the hypothesis of a bacterial etiology of CTH. ..
  28. Localized Aggressive Periodontitis: Microbial & Host Markers for Susceptibility
    Daniel Fine; Fiscal Year: 2007
    ....
  29. Attachment of Oral Actinobacillus to Epithelium
    Daniel Fine; Fiscal Year: 2005
    ..The longterm goal of this application is to use this information to identify targets for therapeutic agents that can interfere with attachment of Aa to oral tissues and thus prevent colonization leading to LAP. ..
  30. Microbial Markers for Periodontal Disease in Children
    Daniel Fine; Fiscal Year: 2005
    ....
  31. CULTIVABLE & UNCULTIVABLE PERIODONTAL SPIROCHETES
    Floyd Dewhirst; Fiscal Year: 2001
    ..abstract_text> ..
  32. CULTIVABLE & UNCULTIVABLE PERIODONTAL SPIROCHETES
    Floyd Dewhirst; Fiscal Year: 2000
    ..abstract_text> ..
  33. CULTIVABLE AND UNCULTIVABLE PERIODONTAL SPIROCHETES
    Floyd Dewhirst; Fiscal Year: 1993
    ..This project will be of importance to the medical community as well as the dental community...
  34. CULTIVABLE AND UNCULTIVABLE PERIODONTAL SPIROCHETES
    Floyd Dewhirst; Fiscal Year: 1992
    ..This project will be of importance to the medical community as well as the dental community...
  35. CULTIVABLE & UNCULTIVABLE PERIODONTAL SPIROCHETES
    Floyd Dewhirst; Fiscal Year: 1999
    ..abstract_text> ..
  36. Bacterial flora in normal esophagus & reflux disorders
    Zhiheng Pei; Fiscal Year: 2002
    ..ii) While GERD initially results from chemical damage, bacterial overgrowth may promote intestinal metaplasia of the esophagus. The proposed study allows qualitative and quantitative examination of this hypothesis. ..
  37. CULTIVABLE & UNCULTIVABLE PERIODONTAL SPIROCHETES
    Floyd Dewhirst; Fiscal Year: 2001
    ..abstract_text> ..
  38. Bacterial flora in normal esophagus & reflux disorders
    Zhiheng Pei; Fiscal Year: 2005
    ..ii) While GERD initially results from chemical damage, bacterial overgrowth may promote intestinal metaplasia of the esophagus. The proposed study allows qualitative and quantitative examination of this hypothesis. ..
  39. Oral Immunology/Microbiology Research Group Annual Mtg
    Daniel Fine; Fiscal Year: 2003
    ..Perpetuation of the OIMRG and its annual meetings greatly enhances the spirit of collegial interaction/collaboration among investigators with expertise in immunology and microbial pathogenesis as related to oral health and disease. ..
  40. CULTIVABLE & UNCULTIVABLE PERIODONTAL SPIROCHETES
    Floyd Dewhirst; Fiscal Year: 2003
    ..abstract_text> ..
  41. Bacterial flora in normal esophagus & reflux disorders
    Zhiheng Pei; Fiscal Year: 2004
    ..ii) While GERD initially results from chemical damage, bacterial overgrowth may promote intestinal metaplasia of the esophagus. The proposed study allows qualitative and quantitative examination of this hypothesis. ..
  42. Bacterial flora in normal esophagus & reflux disorders
    Zhiheng Pei; Fiscal Year: 2003
    ..ii) While GERD initially results from chemical damage, bacterial overgrowth may promote intestinal metaplasia of the esophagus. The proposed study allows qualitative and quantitative examination of this hypothesis. ..
  43. CULTIVABLE & UNCULTIVABLE PERIODONTAL SPIROCHETES
    Floyd Dewhirst; Fiscal Year: 2002
    ..abstract_text> ..
  44. CULTIVABLE & UNCULTIVABLE PERIODONTAL SPIROCHETES
    Floyd Dewhirst; Fiscal Year: 2003
    ..abstract_text> ..
  45. Oral Immunology/Microbiology Annual Meeting
    Daniel Fine; Fiscal Year: 2003
    ..Perpetuation of the OIMRG and its annual meetings greatly enhances the spirit of collegial interaction/collaboration among investigators with expertise in immunology and microbial pathogenesis as related to oral health and disease. ..
  46. CULTIVABLE & UNCULTIVABLE PERIODONTAL SPIROCHETES
    Floyd Dewhirst; Fiscal Year: 2002
    ..abstract_text> ..