anaerobic bacteria

Summary

Top Publications

  1. ncbi Antimicrobial susceptibility of anaerobic bacteria in New Zealand: 1999-2003
    Sally A Roberts
    Department of Microbiology, LabPlus, Auckland District Health Board, Auckland, New Zealand
    J Antimicrob Chemother 57:992-8. 2006
  2. ncbi Electron transfer in syntrophic communities of anaerobic bacteria and archaea
    Alfons J M Stams
    Laboratory of Microbiology, Wageningen University, Dreijenplein 10, 6703 HB Wageningen, The Netherlands
    Nat Rev Microbiol 7:568-77. 2009
  3. ncbi Detection of anaerobic bacteria in high numbers in sputum from patients with cystic fibrosis
    Michael M Tunney
    School of Pharmacy, Medical Biology Centre, Queen s University Belfast, Belfast, United Kingdom
    Am J Respir Crit Care Med 177:995-1001. 2008
  4. ncbi Caldicellulosiruptor kronotskyensis sp. nov. and Caldicellulosiruptor hydrothermalis sp. nov., two extremely thermophilic, cellulolytic, anaerobic bacteria from Kamchatka thermal springs
    Margarita L Miroshnichenko
    Winogradsky Institute of Microbiology, Russian Academy of Sciences, Prospect 60 letiya Oktyabrya 7 2, 117312 Moscow, Russia
    Int J Syst Evol Microbiol 58:1492-6. 2008
  5. pmc Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria
    Wolfgang Haas
    Bausch and Lomb, Inc, 1400 N Goodman St, Rochester, NY 14609, USA
    Antimicrob Agents Chemother 53:3552-60. 2009
  6. ncbi Metabolism of alkylbenzenes, alkanes, and other hydrocarbons in anaerobic bacteria
    A M Spormann
    Department of Civil and Environmental Engineering, Stanford University, CA 94305 4020, USA
    Biodegradation 11:85-105. 2000
  7. ncbi Potential for using thermophilic anaerobic bacteria for bioethanol production from hemicellulose
    P Sommer
    Bio Centrum, Technical University of Denmark, Building 227, DK 2800 Lyngby, Denmark
    Biochem Soc Trans 32:283-9. 2004
  8. ncbi New glycyl radical enzymes catalysing key metabolic steps in anaerobic bacteria
    Thorsten Selmer
    Laboratorium für Mikrobiologie, Philipps Universitat Marburg, D 35032 Marburg, Germany
    Biol Chem 386:981-8. 2005
  9. ncbi The role of anaerobic bacteria in chronic suppurative otitis media in children: implications for medical therapy
    Itzhak Brook
    Department of Pediatrics, Georgetown University School of Medicine, 4431 Albemarle St NW, Washington, DC 20016, USA
    Anaerobe 14:297-300. 2008
  10. ncbi Microbiology and management of joint and bone infections due to anaerobic bacteria
    Itzhak Brook
    Department of Pediatrics, Georgetown University, School of Medicine, 3900 Reservoir Road NW, Washington, DC 20007, USA
    J Orthop Sci 13:160-9. 2008

Research Grants

Detail Information

Publications228 found, 100 shown here

  1. ncbi Antimicrobial susceptibility of anaerobic bacteria in New Zealand: 1999-2003
    Sally A Roberts
    Department of Microbiology, LabPlus, Auckland District Health Board, Auckland, New Zealand
    J Antimicrob Chemother 57:992-8. 2006
    ..This study reports the national trend of antibiotic susceptibility of clinically significant anaerobes in New Zealand...
  2. ncbi Electron transfer in syntrophic communities of anaerobic bacteria and archaea
    Alfons J M Stams
    Laboratory of Microbiology, Wageningen University, Dreijenplein 10, 6703 HB Wageningen, The Netherlands
    Nat Rev Microbiol 7:568-77. 2009
    ..Anaerobic methane oxidation coupled to sulphate reduction is also carried out by syntrophic communities of bacteria and archaea but, as we discuss, the exact mechanism of this syntrophic interaction is not yet understood...
  3. ncbi Detection of anaerobic bacteria in high numbers in sputum from patients with cystic fibrosis
    Michael M Tunney
    School of Pharmacy, Medical Biology Centre, Queen s University Belfast, Belfast, United Kingdom
    Am J Respir Crit Care Med 177:995-1001. 2008
    Pulmonary infection in cystic fibrosis (CF) is polymicrobial and it is possible that anaerobic bacteria, not detected by routine aerobic culture methods, reside within infected anaerobic airway mucus.
  4. ncbi Caldicellulosiruptor kronotskyensis sp. nov. and Caldicellulosiruptor hydrothermalis sp. nov., two extremely thermophilic, cellulolytic, anaerobic bacteria from Kamchatka thermal springs
    Margarita L Miroshnichenko
    Winogradsky Institute of Microbiology, Russian Academy of Sciences, Prospect 60 letiya Oktyabrya 7 2, 117312 Moscow, Russia
    Int J Syst Evol Microbiol 58:1492-6. 2008
    ..The names proposed for these organisms are Caldicellulosiruptor kronotskyensis sp. nov. (type strain 2002(T)=DSM 18902(T)=VKM B-2412(T)) and Caldicellulosiruptor hydrothermalis sp. nov. (type strain 108(T)=DSM 18901(T)=VKM B-2411(T))...
  5. pmc Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria
    Wolfgang Haas
    Bausch and Lomb, Inc, 1400 N Goodman St, Rochester, NY 14609, USA
    Antimicrob Agents Chemother 53:3552-60. 2009
    ..Besifloxacin demonstrated potent, broad-spectrum activity, which was particularly notable against gram-positive and gram-negative isolates that were resistant to other fluoroquinolones and classes of antibacterial agents...
  6. ncbi Metabolism of alkylbenzenes, alkanes, and other hydrocarbons in anaerobic bacteria
    A M Spormann
    Department of Civil and Environmental Engineering, Stanford University, CA 94305 4020, USA
    Biodegradation 11:85-105. 2000
    ..Diverse strains of anaerobic bacteria have been isolated that degrade toluene anaerobically, using nitrate, iron(III), or sulfate as electron ..
  7. ncbi Potential for using thermophilic anaerobic bacteria for bioethanol production from hemicellulose
    P Sommer
    Bio Centrum, Technical University of Denmark, Building 227, DK 2800 Lyngby, Denmark
    Biochem Soc Trans 32:283-9. 2004
    ..A total of 86 enrichment cultures and 58 pure cultures were tested and five candidates were selected which successfully fulfilled the criteria defined for the screening test...
  8. ncbi New glycyl radical enzymes catalysing key metabolic steps in anaerobic bacteria
    Thorsten Selmer
    Laboratorium für Mikrobiologie, Philipps Universitat Marburg, D 35032 Marburg, Germany
    Biol Chem 386:981-8. 2005
    ..Finally, the available whole-genome sequences of an increasing number of strictly or facultative anaerobic bacteria revealed the presence of many more hitherto unknown glycyl radical enzyme (GRE) systems...
  9. ncbi The role of anaerobic bacteria in chronic suppurative otitis media in children: implications for medical therapy
    Itzhak Brook
    Department of Pediatrics, Georgetown University School of Medicine, 4431 Albemarle St NW, Washington, DC 20016, USA
    Anaerobe 14:297-300. 2008
    ..and medical management of chronic suppurative otitis media (CSOM) in children highlighting the role of anaerobic bacteria. In studies that employed adequate method for recovery of anaerobic bacteria polymicrobial aerobic and ..
  10. ncbi Microbiology and management of joint and bone infections due to anaerobic bacteria
    Itzhak Brook
    Department of Pediatrics, Georgetown University, School of Medicine, 3900 Reservoir Road NW, Washington, DC 20007, USA
    J Orthop Sci 13:160-9. 2008
    To describes the microbiology, diagnosis, and management of septic arthritis and osteomyelitis due to anaerobic bacteria.
  11. pmc Reductive debromination of polybrominated diphenyl ethers by anaerobic bacteria from soils and sediments
    Lip Kim Lee
    Division of Environmental Science and Engineering, National University of Singapore, Singapore, Republic of Singapore 117576
    Appl Environ Microbiol 76:794-802. 2010
    ..g., penta- and tetra-BDEs) detected in the environment...
  12. ncbi The role of anaerobic bacteria in bacteremia
    Itzhak Brook
    Georgetown University School of Medicine, 4431 Albemarle St NW, Washington, DC 20016, USA
    Anaerobe 16:183-9. 2010
    b>Anaerobic bacteria remain an important cause of bloodstream infections and account for 1-17% of positive blood cultures...
  13. ncbi Production of phytoestrogen S-equol from daidzein in mixed culture of two anaerobic bacteria
    Xiu Ling Wang
    School of Agricultural Biotechnology, Seoul National University, Seoul 151 742, South Korea
    Arch Microbiol 187:155-60. 2007
    ..Niu-O16. This is the first report in which two metabolic pathways to produce S-equol from daidzein by a mixed culture of bacteria isolated from human and bovine intestinal environments were successfully linked under anaerobic conditions...
  14. ncbi Antimicrobial susceptibility of anaerobic bacteria in Belgium as determined by E-test methodology
    Y Glupczynski
    Department of Clinical Microbiology, Cliniques Universitaires de Mont Godinne, 5530 Yvoir, Belgium
    Eur J Clin Microbiol Infect Dis 28:261-7. 2009
    ..Because of the occurrence of resistance to most classes of current anti-anaerobic antibiotics, it is recommended that the antimicrobial resistance patterns be monitored regularly in order to guide empirical therapy...
  15. ncbi The potential of anaerobic bacteria to degrade chlorinated compounds
    M H van Eekert
    TNO Energy, Environment and Process Innovation, Department of Environmental Biotechnology, Apeldoorn, The Netherlands
    Water Sci Technol 44:49-56. 2001
    ..Specific halo-respiring bacteria may be used to increase the dechlorination activities via bioaugmentation in the case that the appropriate microorganisms are not present at the contaminated site or in the sludge...
  16. ncbi Characterization of culturable anaerobic bacteria from the forestomach of an eastern grey kangaroo, Macropus giganteus
    D Ouwerkerk
    Animal Science, Department of Primary Industries and Fisheries DPI and F, Yeerongpilly, Queensland, Australia
    Lett Appl Microbiol 41:327-33. 2005
    To determine the culturable biodiversity of anaerobic bacteria isolated from the forestomach contents of an eastern grey kangaroo, Macropus giganteus, using phenotypic characterization and 16S rDNA sequence analysis.
  17. pmc Thermostable lipases from the extreme thermophilic anaerobic bacteria Thermoanaerobacter thermohydrosulfuricus SOL1 and Caldanaerobacter subterraneus subsp. tengcongensis
    Marina Royter
    Institute of Technical Microbiology, Hamburg University of Technology TUHH, Kasernenstrasse 12, 21073, Hamburg, Germany
    Extremophiles 13:769-83. 2009
    ..The observed E values for but-3-yn-2-ol butyrate and but-3-yn-2-ol acetate of 21 and 16, respectively, make these enzymes ideal candidates for kinetic resolution of synthetically useful compounds...
  18. pmc In vitro activity of levofloxacin against a selected group of anaerobic bacteria isolated from skin and soft tissue infections
    H M Wexler
    Veterans Administration Medical Center, Department of Medicine, UCLA School of Medicine, Los Angeles, California 90024, USA
    Antimicrob Agents Chemother 42:984-6. 1998
    ..The geometric mean MIC of levofloxacin was lower than those of ofloxacin and ciprofloxacin for every group except Veillonella...
  19. ncbi [Anaerobic bacteria of periodontal pockets in course of periodontitis and premature labor]
    Katarzyna Betleja-Gromada
    Zakład Periodontologii Katedry Stomatologii Zachowawczej i Periodontologii, Pomorskiej Akademii Medycznej w Szczecinie
    Med Dosw Mikrobiol 60:71-8. 2008
    ..The microbial investigation for anaerobic bacteria of deepest periodontal pockets was performed in 35 cases of periodontits...
  20. pmc Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea
    Yangsoon Lee
    Department of Laboratory Medicine, Research Institute of Bacterial Resistance, Yonsei University College of Medicine, 250 Seongsanro, Seodaemun gu, Seoul 120 752, South Korea
    Antimicrob Agents Chemother 54:3993-7. 2010
    We determined the antimicrobial susceptibilities of 255 clinical isolates of anaerobic bacteria collected in 2007 and 2008 at a tertiary-care hospital in South Korea...
  21. ncbi Anaerobic bacteria in 118 patients with deep-space head and neck infections from the University Hospital of Maxillofacial Surgery, Sofia, Bulgaria
    Lyudmila Boyanova
    Department of Microbiology, Medical University of Sofia, University Hospital of Maxillofacial Surgery, Sofia, Bulgaria
    J Med Microbiol 55:1285-9. 2006
    ..In conclusion, the start of empirical treatment could influence the frequency or rate of isolation of Fusobacterium species. The involvement of the Bacteroides fragilis group in some head and neck infections should be considered...
  22. ncbi Urinary tract and genito-urinary suppurative infections due to anaerobic bacteria
    Itzhak Brook
    Department of Pediatrics, Georgetown University School of Medicine, Washington DC 20016, USA
    Int J Urol 11:133-41. 2004
    ..microbiology, diagnosis and management of urinary tract and genito-urinary suppurative infections caused by anaerobic bacteria. The types of infections of the urinary tract in which anaerobes have been involved include para- or ..
  23. ncbi Colonization of lower respiratory tract with anaerobic bacteria in mechanically ventilated patients
    Rene Robert
    Service de Reanimation Medicale, Hopital Jean Bernard CHU, 86021, Poitiers Cedex, France
    Intensive Care Med 29:1062-8. 2003
    To study lower respiratory tract colonization by anaerobic bacteria in ICU patients on prolonged mechanical ventilation using two types of protected tracheal sampling methods.
  24. ncbi [Incidence of anaerobic bacteria in respiratory tract infections]
    Anna Kedzia
    Zakładu Mikrobiologii Jamy Ustnej AM w Gdańsku
    Pneumonol Alergol Pol 71:68-73. 2003
    b>Anaerobic bacteria are predominant components of normal oral cavity, upper respiratory tract, gastrointestinal, genital and skin flora. They are involved in infections such as pneumonia, aspiration pneumonia, lung abscess and empyema...
  25. ncbi Comparative activity of pradofloxacin against anaerobic bacteria isolated from dogs and cats
    Peter Silley
    MB Consult Limited, Lymington, SO41 3TQ, UK
    J Antimicrob Chemother 60:999-1003. 2007
    To compare the intrinsic activity of pradofloxacin, a new fluoroquinolone developed for use in veterinary medicine, with other fluoroquinolones, against anaerobic bacteria isolated from dogs and cats.
  26. ncbi Microbiological analysis of infected root canals from symptomatic and asymptomatic teeth with periapical periodontitis and the antimicrobial susceptibility of some isolated anaerobic bacteria
    R C Jacinto
    Endodontic Area, Dental School of Piracicaba, University of Campinas, Piracicaba, SP, Brazil
    Oral Microbiol Immunol 18:285-92. 2003
    ..with the presence of clinical signs and symptoms, and to test the antibiotic susceptibility of five anaerobic bacteria mostly commonly found in the root canals of symptomatic teeth against various substances using the E-test...
  27. pmc Antiparasitic drug nitazoxanide inhibits the pyruvate oxidoreductases of Helicobacter pylori, selected anaerobic bacteria and parasites, and Campylobacter jejuni
    Paul S Hoffman
    Division of Infectious Diseases and International Health, 409 Lane Road, University of Virginia Health Systems, Charlottesville, VA 22908 1340, USA
    Antimicrob Agents Chemother 51:868-76. 2007
    Nitazoxanide (NTZ) exhibits broad-spectrum activity against anaerobic bacteria and parasites and the ulcer-causing pathogen Helicobacter pylori...
  28. ncbi Antibacterial effect of bioactive glasses on clinically important anaerobic bacteria in vitro
    Outi Leppäranta
    Department of Medical Microbiology, University of Turku, Kiinamyllynkatu 13, Turku, Finland
    J Mater Sci Mater Med 19:547-51. 2008
    ..Glass S53P4 had a strong growth-inhibitory effect on all pathogens tested. Glass 13-93 and sol-gel derived material CaPSiO II showed moderate antibacterial properties...
  29. pmc Octreotide induced prolongation of colonic transit increases faecal anaerobic bacteria, bile acid metabolising enzymes, and serum deoxycholic acid in patients with acromegaly
    L A Thomas
    Gastroenterology Unit, Division of Medicine, GKT School of Medicine, Kings College, London, UK
    Gut 54:630-5. 2005
    ....
  30. pmc In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria
    D M Citron
    R M Alden Research Laboratory, 6133 Bristol Parkway, Suite 175, Culver City, CA 90404, USA
    Antimicrob Agents Chemother 54:1627-32. 2010
    ..novel, parenteral, broad-spectrum cephalosporin, and four comparator antimicrobials were determined against anaerobic bacteria. Against Gram-positive strains, the activity of ceftaroline was similar to that of amoxicillin-clavulanate ..
  31. ncbi Activities of four frog skin-derived antimicrobial peptides (temporin-1DRa, temporin-1Va and the melittin-related peptides AR-23 and RV-23) against anaerobic bacteria
    Edit Urban
    Department of Clinical Microbiology, Faculty of Medicine, University of Szeged, Szeged, Hungary
    Int J Antimicrob Agents 29:317-21. 2007
    ..draytonii) were evaluated against a range of reference strains and clinical isolates of anaerobic bacteria. These peptides were selected because they show broad-spectrum growth inhibitory activity against reference ..
  32. ncbi Antimicrobial activity of some Pacific Northwest woods against anaerobic bacteria and yeast
    W H Johnston
    College of Veterinary Medicine, 105 Magruder Hall, Oregon State University, Corvallis, Oregon 97331, USA
    Phytother Res 15:586-8. 2001
    ..cedar (Thuja plicata) and ponderosa pine (Pinus ponderosa) were tested for antimicrobial activity against anaerobic bacteria and yeast...
  33. pmc Molecular microbial diversity of an anaerobic digestor as determined by small-subunit rDNA sequence analysis
    J J Godon
    Laboratoire de Biotechnologie de l Environnement, Institut National de la Recherche Agronomique, Narbonne, France
    Appl Environ Microbiol 63:2802-13. 1997
    ..In contrast, the three other Archaea OTUs are unusual and are related to thermophilic microorganisms such as Crenarchaea or Thermoplasma spp. Five percent of the sequences analyzed were chimeras and were removed from the analysis...
  34. ncbi The susceptibility of anaerobic bacteria isolated from periodontal diseases to photodynamic inactivation with Fotolon (chlorin e6)
    Zuzanna Drulis-Kawa
    Institute of Genetics and Microbiology, University of Wrocław, Poland
    Pol J Microbiol 54:305-10. 2005
    ..the activity of the Fotolon sensitizer, composed of chlorin e6 and polyvinylpyrrolidone (PVP), against anaerobic bacteria isolated from periodontal diseases. Over 99...
  35. ncbi Comparison of 3 swab transport systems for direct release and recovery of aerobic and anaerobic bacteria
    Kenneth G Van Horn
    Focus Diagnostics, Inc, Cypress, CA 90630, USA
    Diagn Microbiol Infect Dis 62:471-3. 2008
    ....
  36. ncbi Pericarditis due to anaerobic bacteria
    Itzhak Brook
    Department of Pediatrics, Georgetown University School of Medicine, Washington, DC, USA
    Cardiology 97:55-8. 2002
    This review describes the microbiology, diagnosis and management of pericarditis due to anaerobic bacteria. The predominant anaerobes recovered from patients with pericarditis were: gram-negative bacilli (mostly of the Bacteroides ..
  37. ncbi 6-Oxocyclohex-1-ene-1-carbonyl-coenzyme A hydrolases from obligately anaerobic bacteria: characterization and identification of its gene as a functional marker for aromatic compounds degrading anaerobes
    Kevin Kuntze
    Institute of Biochemistry, University of Leipzig, Leipzig, Germany
    Environ Microbiol 10:1547-56. 2008
    In anaerobic bacteria, most aromatic growth substrates are channelled into the benzoyl-coenzyme A (CoA) degradation pathway where the aromatic ring is dearomatized and cleaved into an aliphatic thiol ester...
  38. ncbi Propagation of anaerobic bacteria within an aerobic multi-species chronic wound biofilm model
    Y Sun
    Research and Testing Laboratory, Lubbock, TX, USA
    J Wound Care 18:426-31. 2009
    ..In order to better screen antimicrobial and antibiofilm therapeutics, we evaluated the ability of key anaerobes to incorporate and propagate within our aerobic chronic wound biofilm...
  39. pmc 16S rRNA gene sequencing in routine identification of anaerobic bacteria isolated from blood cultures
    Ulrik Stenz Justesen
    Department of Clinical Microbiology, Odense University Hospital, Odense, Denmark
    J Clin Microbiol 48:946-8. 2010
    A comparison between conventional identification and 16S rRNA gene sequencing of anaerobic bacteria isolated from blood cultures in a routine setting was performed (n = 127)...
  40. ncbi Acetate versus hydrogen as direct electron donors to stimulate the microbial reductive dechlorination process at chloroethene-contaminated sites
    Jianzhong He
    School of Civil and Environmental Engineering, Georgia Institute of Technology, Atlanta 30332 0512, USA
    Environ Sci Technol 36:3945-52. 2002
    ..These findings demonstrated that either acetate or H2 alone can be sufficient to promote complete..
  41. ncbi Changes in bacterial profile during amebiasis: demonstration of anaerobic bacteria in ALA pus samples
    Rekha Rani
    School of Life Sciences, Jawaharlal Nehru University, New Delhi, India
    Am J Trop Med Hyg 75:880-5. 2006
    ..In addition, PCR revealed metronidazole resistance genes in fecal and pus samples of metronidazole-treated individuals. Re-examination of the ameba-bacterium relationship in amebiasis is suggested...
  42. ncbi Third Belgian multicentre survey of antibiotic susceptibility of anaerobic bacteria
    Ingrid Wybo
    Academisch Ziekenhuis Vrije Universiteit Brussel, 1090 Brussels, Belgium
    J Antimicrob Chemother 59:132-9. 2007
    ..To collect recent data on the susceptibility of anaerobes and to compare them with results from previous studies...
  43. pmc In vitro activities of gatifloxacin, two other quinolones, and five nonquinolone antimicrobials against obligately anaerobic bacteria
    R Schaumann
    Institute for Medical Microbiology and Epidemiology of Infectious Diseases, University of Leipzig, Leipzig, Germany
    Antimicrob Agents Chemother 43:2783-6. 1999
    ..For all strains tested, gatifloxacin MICs at which 50 and 90% of the isolates were inhibited were 0.5 and 2 mg/liter, respectively, and were 3 to 4 dilution steps lower than, e.g., ciprofloxacin...
  44. ncbi The microbial spectrum of brain abscess with special reference to anaerobic bacteria
    R Chaudhry
    Department of Microbiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
    Br J Neurosurg 12:127-30. 1998
    ..These findings indicate the microbial complexity of brain abscess and the need to target antimicrobial therapy against both the aerobic and anaerobic components of infection...
  45. pmc Differential recognition of obligate anaerobic bacteria by human mannose-binding lectin
    R Townsend
    Division of Genomic Medicine, University of Sheffield, United Kingdom
    Clin Exp Immunol 124:223-8. 2001
    ..The attachment of MBL to a wide range of anaerobic bacteria associated with human disease and colonization was surveyed...
  46. ncbi Pericarditis caused by anaerobic bacteria
    Itzhak Brook
    Department of Pediatrics and Medicine, Georgetown University School of Medicine, Washington, DC 20016, USA
    Int J Antimicrob Agents 33:297-300. 2009
    This review describes the microbiology, diagnosis and management of pericarditis due to anaerobic bacteria. The predominant anaerobes isolated from patients with pericarditis are Gram-negative bacilli (mostly Bacteroides fragilis group) ..
  47. ncbi Distribution of anaerobic bacteria among pregnant periodontitis patients who experience preterm delivery
    Edit Urban
    Institute of Clinical Microbiology, Faculty of Medicine, University of Szeged, H 6701 Szeged, P O Box 427, Hungary
    Anaerobe 12:52-7. 2006
    ....
  48. pmc In vitro activities of a new des-fluoro(6) quinolone, garenoxacin, against clinical anaerobic bacteria
    A Liebetrau
    Institute of Medical Microbiology and Epidemiology of Infectious Diseases, University of Leipzig, Leipzig, Germany
    Antimicrob Agents Chemother 47:3667-71. 2003
    ..0.25 and 0.5; Clostridium spp., 0.25 and 1; Clostridium difficile, 2 and >64; Bifidobacterium spp., 1 and 2; Eggerthella lenta, 0.25 and 1; Propionibacterium spp., 0.5 and 0.5; gram-positive cocci, 0.125 and 0.25...
  49. pmc Novel major bacterial candidate division within a municipal anaerobic sludge digester
    Rakia Chouari
    CNRS UMR 8030, Genoscope, 2, rue Gaston Crémieux, 91057 Evry, France
    Appl Environ Microbiol 71:2145-53. 2005
    ..5% of the clone library, respectively. This inventory expands the known diversity of the latter bacterial division-level lineages...
  50. ncbi Bacterial vaginosis and anaerobic bacteria are associated with endometritis
    Catherine L Haggerty
    University of Pittsburgh, 130 DeSoto St, 516 Parran Hall, Pittsburgh, PA 15261, USA
    Clin Infect Dis 39:990-5. 2004
    ..Chlamydia trachomatis and/or Neisseria gonorrhoeae account for approximately one-third to one-half of pelvic inflammatory disease (PID) cases. Thus, up to 70% of cases have an unknown, nongonococcal/nonchlamydial microbial etiology...
  51. ncbi Detection of potentially novel bacterial components of the human skin microbiota using culture-independent molecular profiling
    Itaru Dekio
    Department of Dermatology, School of Medicine, Keio University, Tokyo 160 8582, Japan
    J Med Microbiol 54:1231-8. 2005
    ..Culture-independent genetic profiling of 16S rRNA genes for detecting human cutaneous microbiota has allowed us to detect potentially novel components of the cutaneous microbiota in humans...
  52. pmc Culturing aerobic and anaerobic bacteria and mammalian cells with a microfluidic differential oxygenator
    Raymond H W Lam
    Department of Mechanical Engineering, Hatsopoulos Microfluids Laboratory, Massachusetts Institute of Technology, Room 3 246, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA
    Anal Chem 81:5918-24. 2009
    ..Growth characteristics of the selected species were analyzed as a function of eight discrete DO concentrations, ranging from 0 ppm (anaerobic) to 42 ppm (fully saturated)...
  53. pmc In vitro activities of ramoplanin, teicoplanin, vancomycin, linezolid, bacitracin, and four other antimicrobials against intestinal anaerobic bacteria
    D M Citron
    R M Alden Research Laboratory, Santa Monica, California 90404, USA
    Antimicrob Agents Chemother 47:2334-8. 2003
    ....
  54. ncbi Acidification of methanol-fed anaerobic granular sludge bioreactors by cobalt deprivation: Induction and microbial community dynamics
    Fernando G Fermoso
    Sub Department of Environmental Technology, Wageningen University, Biotechnion Bomenweg 2, P O Box 8129, 6700 EV Wageningen, The Netherlands
    Biotechnol Bioeng 99:49-58. 2008
    ..The loss of SMA on methanol can thus be used as an accurate parameter to predict reactor acidification of methanol-fed UASB reactors operating under cobalt limiting conditions...
  55. ncbi Membrane lipids of mesophilic anaerobic bacteria thriving in peats have typical archaeal traits
    Johan W H Weijers
    Royal Netherlands Institute for Sea Research NIOZ, Department of Marine Biogeochemistry and Toxicology, PO Box 59, 1790 AB Den Burg Texel, The Netherlands
    Environ Microbiol 8:648-57. 2006
    ....
  56. ncbi Thermostable esterase from Thermoanaerobacter tengcongensis: high-level expression, purification and characterization
    Jian Zhang
    State Key Laboratory of Microbial Resources and Center for Molecular Microbiology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, P R China
    Biotechnol Lett 25:1463-7. 2003
    ..In addition, it was stable for 1 h at 37 degrees C in 1% CHAPS and Triton X-100 but not stable in 1% Tween 20 or SDS...
  57. ncbi Management of anaerobic infection
    Itzhak Brook
    Expert Rev Anti Infect Ther 2:153-8. 2004
    ..Some antimicrobials have poor activity against anaerobic bacteria. The more suitable agents include penicillins, cephalosporins, carbapenems, chloramphenicol, clindamycin, ..
  58. pmc Serum antibodies to oral anaerobic bacteria in patients with rheumatoid arthritis
    Mesut Ogrendik
    Department of Physical Medicine and Rehabilitation, Nazilli State Hospital, Nazilli, Aydin, Turkey
    MedGenMed 7:2. 2005
    ..This study was conducted to determine the component that causes the disease in rheumatoid arthritis (RA), which shows great resemblance to periodontitis in a pathologic context...
  59. ncbi Prevalence of antibiotic resistance in anaerobic bacteria: worrisome developments
    David W Hecht
    Hines Veterans Affairs Hospital, Hines, USA
    Clin Infect Dis 39:92-7. 2004
    Antibiotic-resistant anaerobic bacteria have become increasingly recognized as a confounding factor in the selection of therapeutic agents...
  60. ncbi Risk factors for mortality in patients with anaerobic bacteremia
    J R Wilson
    Departments of Laboratory Medicine and Medicine, University of Washington Medical Center, 1959 Northeast Pacific Street, Box 357110, Seattle, WA 98195 7110, USA
    Eur J Clin Microbiol Infect Dis 23:310-6. 2004
    ..All patients who had anaerobic bacteria isolated from blood over a 19-month period (from 1 September 1998 to 1 April 2000) at two urban teaching ..
  61. ncbi Dehydration of (R)-2-hydroxyacyl-CoA to enoyl-CoA in the fermentation of alpha-amino acids by anaerobic bacteria
    Jihoe Kim
    Laboratorium für Mikrobiologie, Fachbereich Biologie, Philipps Unversität, Karl von Frisch Strasse, D 35032 Marburg, Germany
    FEMS Microbiol Rev 28:455-68. 2004
    ..The transfer is catalysed by a membrane-bound NADH-ferredoxin oxidoreductase driven by an electrochemical Na(+)-gradient. This enzyme is related to the Rnf proteins involved in Rhodobacter capsulatus nitrogen fixation...
  62. ncbi Isolation from oil reservoirs of novel thermophilic anaerobes phylogenetically related to Thermoanaerobacter subterraneus: reassignment of T. subterraneus, Thermoanaerobacter yonseiensis, Thermoanaerobacter tengcongensis and Carboxydibrachium pacificum to
    Marie Laure Fardeau
    IRD, UR101 Extrêmophiles, IFR BAIM, Universités de Provence et de la Méditerranée, ESIL case 925, 163 Avenue de Luminy, 13288 Marseille Cedex 9, France
    Int J Syst Evol Microbiol 54:467-74. 2004
    ..comb. nov., Caldanaerobacter subterraneus subsp. yonseiensis subsp. nov., comb. nov., Caldanaerobacter subterraneus subsp. tengcongensis subsp. nov., comb. nov. and Caldanaerobacter subterraneus subsp. pacificus subsp. nov., comb. nov...
  63. ncbi Radical-mediated dehydration reactions in anaerobic bacteria
    Wolfgang Buckel
    Laboratorium für Mikrobiologie, Fachbereich Biologie, Philipps Universitat, D 35032 Marburg, Germany
    Biol Chem 386:951-9. 2005
    ..b>Anaerobic bacteria, however, ferment amino acids via alpha- or gamma-hydroxyacyl-CoA, dehydrations of which involve the ..
  64. ncbi The role of anaerobic bacteria in tonsillitis
    Itzhak Brook
    Department of Pediatrics, Georgetown University School of Medicine, 4431 Albemarlr St NW, Washington, DC 20016, USA
    Int J Pediatr Otorhinolaryngol 69:9-19. 2005
    This review summarizes the information that supports the potential importance of anaerobic bacteria in tonsillitis...
  65. pmc Overcoming the hypoxic barrier to radiation therapy with anaerobic bacteria
    Chetan Bettegowda
    Howard Hughes Medical Institute and Sidney Kimmel Cancer Center, Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA
    Proc Natl Acad Sci U S A 100:15083-8. 2003
    ..The low level of oxygenation within tumors is a major cause of radiation treatment failures. We theorized that anaerobic bacteria that can selectively destroy the hypoxic regions of tumors would enhance the effects of radiation...
  66. ncbi Comparison of agar plate and real-time PCR on enumeration of Lactobacillus, Clostridium perfringens and total anaerobic bacteria in dog faeces
    C J Fu
    Department of Animal Sciences, University of Missouri, Columbia, MO 65211, USA
    Lett Appl Microbiol 42:490-4. 2006
    To compare agar plate and real-time PCR methods on enumeration of total anaerobic bacteria, Lactobacillus and Clostridium perfringens in dog faeces.
  67. ncbi The incidence of anaerobes in the sputum of patients with cystic fibrosis
    L A Jewes
    Department of Bacteriology, Royal Hallamshire Hospital, Sheffield
    J Med Microbiol 31:271-4. 1990
    ..and anaerobic gram-positive cocci. Anaerobes were isolated more often from sputum liquefied by sonication than from unliquefied sputum, suggesting that they were unlikely to be oropharyngeal contaminants...
  68. ncbi The cellulosome and cellulose degradation by anaerobic bacteria
    W H Schwarz
    Research Group Microbial Biotechnology, Technische Universitat Munchen, Freising Weihenstephan, Germany
    Appl Microbiol Biotechnol 56:634-49. 2001
    ..Specific enzymes act in synergy to elicit effective hydrolysis. In contrast, anaerobic bacteria possess a unique extracellular multi-enzyme complex, called cellulosome...
  69. ncbi Elucidation of the pathways of catabolic glutamate conversion in three thermophilic anaerobic bacteria
    C M Plugge
    Laboratory of Microbiology, Wageningen University, H van Suchtelenweg 4, 6703 CT Wageningen, The Netherlands
    Arch Microbiol 176:29-36. 2001
    ..Glutamate was converted to propionate oxidatively via the intermediates succinyl-CoA and methylmalonyl-CoA. A minor part of the succinyl-CoA was converted to succinate and excreted...
  70. pmc Clinical review: bacteremia caused by anaerobic bacteria in children
    Itzhak Brook
    Department of Pediatrics, Georgetown University School of Medicine, Washington, DC, USA
    Crit Care 6:205-11. 2002
    This review describes the microbiology, diagnosis and management of bacteremia caused by anaerobic bacteria in children. Bacteroides fragilis, Peptostreptococcus sp., Clostridium sp., and Fusobacterium sp...
  71. ncbi Activity of BMS284756 (T-3811) tested against anaerobic bacteria, Campylobacter jejuni, Helicobacter pylori and Legionella spp
    P R Rhomberg
    University of Iowa College of Medicine, Iowa City, IA, USA
    Diagn Microbiol Infect Dis 40:45-9. 2001
    ..jejuni, H. pylori, Legionella spp. and most anaerobes, thus the potential role of this des-fluoro compound for treatment of infections caused by these fastidious species warrants further investigation...
  72. ncbi Current susceptibility patterns of anaerobic bacteria
    H M Wexler
    Research Services Veterans Administration Medical Center, West Los Angeles, California 90073, USA
    Yonsei Med J 39:495-501. 1998
    ..resources mandate that careful consideration be given to the necessity for routine susceptibility testing of anaerobic bacteria. Determination of appropriate therapy can be based on published antibiograms; however, since patterns may ..
  73. ncbi Random sequence analysis of genomic DNA of an anaerobic, thermophilic, halophilic bacterium, Halothermothrix orenii
    B N Mijts
    Microbial Discovery Research Unit, School of Biomolecular and Biomedical Sciences, Faculty of Science, Griffith University, Brisbane, Queensland, Australia
    Extremophiles 5:61-9. 2001
    ..orenii as compared to the mesophilic haloanaerobes. This lack may be the result of reduced activity of acidic, halophilic enzymes at high temperatures and intermediate salt concentrations...
  74. ncbi In vitro activities of fourteen antimicrobial agents against obligately anaerobic bacteria
    R Schaumann
    Institute for Medical Microbiology and Epidemiology of Infectious Diseases, University of Leipzig, Liebigstr 24, D 04103, Leipzig, Germany
    Int J Antimicrob Agents 16:225-32. 2000
    ..in vitro activities of fourteen antimicrobial agents were tested against 292 clinical isolates of obligately anaerobic bacteria using the broth microdilution technique...
  75. ncbi Facultative or obligate anaerobic bacteria have the potential for multimodality therapy of solid tumours
    Ming Q Wei
    Department of Medicine, University of Queensland, Prince Charles Hospital, Brisbane, Qld 4032, Australia
    Eur J Cancer 43:490-6. 2007
    ..This micro-milieu provides a haven for anaerobic bacteria. The strictly anaerobic clostridia have several advantages over other facultative anaerobes such as ..
  76. pmc Role of Fusobacterium nucleatum and coaggregation in anaerobe survival in planktonic and biofilm oral microbial communities during aeration
    D J Bradshaw
    Centre for Applied Microbiology and Research, Salisbury SP4 0JG, United Kingdom
    Infect Immun 66:4729-32. 1998
    ..001) in both the planktonic phase and in 4-day biofilms, while the numbers of facultatively anaerobic bacteria increased in these communities. Coaggregation-mediated interactions between F...
  77. ncbi Thermosipho melanesiensis sp. nov., a new thermophilic anaerobic bacterium belonging to the order Thermotogales, isolated from deep-sea hydrothermal vents in the southwestern Pacific Ocean
    E Antoine
    Laboratoire de Biotechnologie des Microorganismes Hydrothermaux, DRV VP, Center IFREMER de Brest, France
    Int J Syst Bacteriol 47:1118-23. 1997
    ..africanus). On the basis of these observations, we propose that the new organism should be described as a new species, Thermosipho melanesiensis. The type strain of T. melanesiensis is BI429...
  78. pmc Identification and molecular characterization of the aco genes encoding the Pelobacter carbinolicus acetoin dehydrogenase enzyme system
    F B Oppermann
    Institut für Mikrobiologie der Georg August Universität zu Göttingen, Federal Republic of Germany
    J Bacteriol 176:469-85. 1994
    ..carbinolicus acetoin dehydrogenase enzyme system to 2-oxo acid dehydrogenase complexes...
  79. ncbi A new family of very long chain alpha,omega-dicarboxylic acids is a major structural fatty acyl component of the membrane lipids of Thermoanaerobacter ethanolicus 39E
    S Jung
    Department of Biochemistry, Michigan State University, East Lansing 48824
    J Lipid Res 35:1057-65. 1994
    ....
  80. ncbi Ocular infections due to anaerobic bacteria in children
    Itzhak Brook
    Department of Pediatrics, Georgetown University, Washington, DC, USA
    J Pediatr Ophthalmol Strabismus 45:78-84. 2008
    The recent increased recovery of anaerobic bacteria from children has led to greater appreciation of the role these organisms play in pediatric infections at all body sites, including the eye...
  81. ncbi Anaerobic pleuropulmonary infection
    M E Levison
    Division of Infectious Diseases, MCP Hahnemann University, Philadelphia, Pennsylvania 19129, USA
    Curr Opin Infect Dis 14:187-91. 2001
    ..Several new drugs that have in-vitro activity against obligate anaerobes have recently become available for empirical treatment of pneumonia...
  82. ncbi Carbon monoxide-dependent energy metabolism in anaerobic bacteria and archaea
    Ellen Oelgeschläger
    Institut für Molekulare Biowissenschaften, Abteilung Molekulare Mikrobiologie und Bioenergetik, Johann Wolfgang Goethe Universitat, Max von Laue Str 9, 60438 Frankfurt am Main, Germany
    Arch Microbiol 190:257-69. 2008
    ....
  83. ncbi Anaerobic bacteria in upper respiratory tract and other head and neck infections
    Itzhak Brook
    Department of Pediatrics, Georgetown University School of Medicine, Washington, DC, USA
    Ann Otol Rhinol Laryngol 111:430-40. 2002
    b>Anaerobic bacteria are common in chronic upper respiratory tract and head and neck infections...
  84. ncbi Cutaneous and subcutaneous infections in newborns due to anaerobic bacteria
    Itzhak Brook
    Department of Pediatrics, Georgetown University School of Medicine, Washington, DC, USA
    J Perinat Med 30:197-208. 2002
    ..the microbiology and management of the major cutaneous and subcutaneous infections in newborns where anaerobic bacteria predominate: omphalitis, necrotizing fasciitis, breast abscess, and scalp infection following intrauterine ..
  85. ncbi Linearly concatenated cyclobutane lipids form a dense bacterial membrane
    Jaap S Sinninghe Damsté
    Royal Netherlands Institute for Sea Research NIOZ, Department of Marine Biogeochemistry and Toxicology, PO Box 59, 1790 AB Den Burg, The Netherlands
    Nature 419:708-12. 2002
    ..Our results further illustrate that microbial membrane lipid structures are far more diverse than previously recognized...
  86. ncbi Novel chemolithotrophic, thermophilic, anaerobic bacteria Thermolithobacter ferrireducens gen. nov., sp. nov. and Thermolithobacter carboxydivorans sp. nov
    T Sokolova
    Winogradsky Institute of Microbiology, Russian Academy of Sciences, Prospect 60 letiya Oktyabrya 7 2, 117312, Moscow, Russia
    Extremophiles 11:145-57. 2007
    ..Strain R1(T) is the type strain for the hydrogenogenic, CO-oxidizing Thermolithobacter carboxydivorans sp. nov. (DSM 7242(T), VKM 2359(T))...
  87. ncbi Characteristics of brain abscess with isolation of anaerobic bacteria
    Gwenael Le Moal
    Service de Medecine Interne et Maladies Infectieuses, CHU La Miletrie, Poitiers, France
    Scand J Infect Dis 35:318-21. 2003
    ..BA due to anaerobic bacteria (group A) were compared with other cases (group B) to determine the frequency and eventual characteristics ..
  88. ncbi Anaerobic bacteria in jaw cysts
    I A Iatrou
    Oral and Maxillofacial Surgery Clinic, Dental School, Athens University, Greece
    Br J Oral Maxillofac Surg 26:62-9. 1988
    ..0%). Antibiotic sensitivity tests of the isolated anaerobic cocci to a group of nine antibiotics revealed chloramphenicol and minocycline as the most effective. All anaerobic rods tested, were sensitive to metronidazole...
  89. ncbi Screening of thermophilic anaerobic bacteria for solid substrate cultivation on lignocellulosic substrates
    Mari S Chinn
    Department of Biosystems and Agricultural Engineering, University of Kentucky, 215 C E Barnhart Building, Lexington, Kentucky 40546 0276, USA
    Biotechnol Prog 22:53-9. 2006
    ..The production potential of nine thermophilic anaerobic bacteria was examined on corn stover, sugar cane bagasse, paper pulp sludge, and wheat bran in submerged liquid ..
  90. ncbi Bay 12-8039, a new 8-methoxy-quinolone: comparative in-vitro activity with nine other antimicrobials against anaerobic bacteria
    A P Macgowan
    Bristol Centre for Antimicrobial Research and Evaluation, Southmead Health Services NHS Trust, UK
    J Antimicrob Chemother 40:503-9. 1997
    The in-vitro activity of a new 8-methoxy-quinolone, Bay 12-8039, was assessed against 218 anaerobic bacteria. Ninety-eight per cent of strains belonging to the Bacteroides fragilis group (n = 65) were inhibited by < or = 2 mg/L of Bay ..
  91. pmc Anaerobic mineralization of stable-isotope-labeled 2-methylnaphthalene
    E R Sullivan
    Biotechnology Center for Agriculture and the Environment, Cook College, Rutgers, The State University of New Jersey, New Brunswick, New Jersey 08901, USA
    Appl Environ Microbiol 67:4353-7. 2001
    ..Also detected were carboxylated 2-MNAPs, suggesting the presence of an alternative pathway for 2-MNAP degradation...
  92. ncbi New anaerobic process of nitrogen removal
    S Kalyuzhnyi
    Department of Chemical Enzymology, Chemistry Faculty, Moscow State University, 119992 Moscow, Russia
    Water Sci Technol 54:163-70. 2006
    ..The paper describes also some characteristics of DEAMOX sludge, as well as the preliminary results of its microbiological characterization...
  93. ncbi Long-term, high-rate anaerobic biological treatment of whey wastewaters at psychrophilic temperatures
    Sharon McHugh
    Microbial Ecology Laboratory, Department of Microbiology, National University of Ireland, Galway, Ireland
    Bioresour Technol 97:1669-78. 2006
    ....
  94. ncbi Oxidative and thermo-oxidative co-treatment with anaerobic digestion of excess municipal sludge
    J A Cacho Rivero
    Department of Civil and Environmental Engineering, University of Cincinnati, 765 Baldwin Hall, Cincinnati, Ohio 45221, USA
    Water Sci Technol 52:237-44. 2005
    ..1 and 26.9% respectively was observed. The performances of the different configurations were also evaluated with parameters such as COD, TKN, ammonia, and fecal coliform concentration...
  95. ncbi Comparative study of MBR and activated sludge in the treatment of paper mill wastewater
    M Lerner
    Department of Civil and Environmental Engineering, Technion Israel Institute of Technology, Haifa
    Water Sci Technol 55:23-9. 2007
    ....
  96. ncbi Assessment of electrochemical and chemical coagulation as post-treatment for the effluents of a UASB reactor treating cellulose pulp mill wastewater
    A P Buzzini
    Department of Hydraulics and Sanitation, School of Engineering of São Carlos, University of Sao Paulo, Brazil
    Water Sci Technol 52:183-8. 2005
    ..The addition of a high molecular weight cationic polymer enhanced both COD and color removal. Both post-treatment processes are technically feasible...
  97. ncbi Combined biological and physico-chemical treatment of baker's yeast wastewater
    S Kalyuzhnyi
    Department of Chemical Enzymology, Chemistry Faculty, Moscow State University, 119992 Moscow, Russia
    Water Sci Technol 52:175-81. 2005
    ....
  98. ncbi The efficacy of ozone as a pre- and post-treatment option for UASB-treated food processing wastewaters
    G O Sigge
    Department of Food Science, University of Stellenbosch, Private Bag Xl, Matieland, 7602, South Africa
    Water Sci Technol 52:167-73. 2005
    ..Subsequent increases in organic loading rate (OLR) from 2.4 to 3.4 kgCOD m(-3) x d(-1) did not affect reactor performance. By including a final post-ozonation treatment to this UASB effluent a total COD reduction of 99.2% was achieved...
  99. ncbi Study on performance of granular ANAMMOX process and characterization of the microbial community in sludge
    Y Yang
    Department of Environmental Science and Engineering, Tsinghua University, Beijing 100084, China
    Water Sci Technol 54:197-207. 2006
    ..The composition of 'aerobic' ammonium-oxidizing bacteria is only 2% of all of bacteria in reactors...
  100. ncbi Thermophilic treatment by anaerobic granular sludge as an effective approach to accelerate the electron transfer and improve the reductive decolorization of azo dyes in bioreactors
    A B dos Santos
    Sub Department of Environmental Technology, Wageningen University, Wageningen, The Netherlands
    Water Sci Technol 52:363-9. 2005
    ..Furthermore, similar decolorizations were found at 55 degrees C between the AQDS-free and AQDS-supplemented reactors, whereas a significant difference (up to 3.6-fold) on dye reduction occurred at 30 degrees C...
  101. ncbi Fermentative hydrogen production in a system using anaerobic digester sludge without heat treatment as a biomass source
    I Shizas
    Department of Civil Engineering, University of Toronto, 35 St George Street, Toronto, Ontario M5S 1A4, Canada
    Water Sci Technol 52:139-44. 2005
    ..The operational controls examined were not sufficient to eliminate hydrogen-consuming methanogens for longer than approximately one week, and thus further methods must be developed...

Research Grants62

  1. The role of novel, uncultivable bacteria in incident PID
    CATHERINE L contact HAGGERTY; Fiscal Year: 2011
    ..Similarly, anaerobic bacteria and bacterial vaginosis (BV) have also been associated with PID, yet little is known about the role of ..
  2. A Novel Drug for Septicemia Targets A1 ARs
    Constance Neely Wilson; Fiscal Year: 2010
    ..be used to cover Gram-negative and Gram-positive aerobic bacteria in combination with clindamycin to cover anaerobic bacteria. These expanded studies will evaluate the efficacy of L-97-1 at later time points after CLP to determine ..
  3. Molecular Epidemiology of the Vaginal Microbiome
    Rebecca M Brotman; Fiscal Year: 2013
    ..BV), a condition in which lactic acid-producing bacteria are supplanted by a diverse array of strictly anaerobic bacteria. Epidemiologically, BV has been shown to be an independent risk factor for adverse outcomes including ..
  4. Regulatory Mechanisms Controlling Expression of P. gingivalis Surface Structures
    MARY ELLEN DAVEY; Fiscal Year: 2013
    ..The proliferation of anaerobic bacteria in the subgingival crevice is central to progression of this chronic disease, with Porphyromonas gingivalis ..
  5. The Microbial Ecology of Bacterial Vaginosis: A Fine Scale Resolution Metagenomic
    Jacques Ravel; Fiscal Year: 2011
    ..BV), a condition in which lactic acid producing bacteria are supplanted by a diverse array of strictly anaerobic bacteria. BV has been shown to be an independent risk factor for adverse outcomes including preterm delivery and low ..
  6. Small non-coding RNAs in Porphyromonas gingivalis
    JANINA P contact LEWIS; Fiscal Year: 2010
    ..So far, however, the role of sncRNAs in P. gingivalis and other anaerobic bacteria has not been investigated. It is noteworthy that, analysis of the genomic sequence of P...
  7. The Role of Anaerobic Bacterial Infection in Cystic Fibrosis
    RICHARD CHARLES BOUCHER; Fiscal Year: 2013
    ..3) the high density (equal to Pseudomonas), and changes with acute exacerbation support the notion that anaerobic bacteria are pathogenic in the CF lung...
  8. The effect of the penile microbiome on BV, GUD, and genital epithelial trauma
    SUPRIYA DINESH MEHTA; Fiscal Year: 2013
    ..our MMC trial in Kenya and the Ugandan MMC trial, circumcised men had lower prevalence and amount of penile anaerobic bacteria, several species of which are associated with Bacterial vaginosis (BV)...
  9. A Dual-drug Delivery to Inhibit Causes of Periodontal Diseases
    RAJIV KUMAR SATSANGI; Fiscal Year: 2012
    ..provided by applicant): The pathogenicity of periodontal disease is linked mainly with gram-negative anaerobic bacteria and with tissue damage caused by the host response to infection...
  10. The Role of Stress Induced Hypoxia in Periodontitis
    PRAVEEN GAJENDRAREDDY; Fiscal Year: 2009
    ..Lower tissue oxygen levels could decrease immune potential, and favor the growth of anaerobic bacteria that have been associated with periodontal pathology...
  11. Direct gas sensing and repellent response to toxic gases in anaerobic pathogens
    Charles W Hespen; Fiscal Year: 2013
    ..However, the signal propagation mechanisms of these domains in obligate anaerobic bacteria are still unknown. Previously characterized gas-sensing chemotaxis proteins respond indirectly to gases...
  12. Phase I study of Clostridium novyi-NT spores in solid tumor cancer patients
    Luis A Diaz; Fiscal Year: 2010
    ..For this purpose, we have investigated the potential of using live anaerobic bacteria. In particular, we developed a strain, termed Clostridium novyi-NT(C...
  13. Determination of Porphyromonas antimicrobial resistance mechanisms by Tn-Seq
    BRIAN ANDREW KLEIN; Fiscal Year: 2013
    ..gingivalis isolates has been reported. Metronidazole is a nitroimidazole with activity against many anaerobic bacteria, including P.gingivalis...
  14. 11th Biennial Congress - Anaerobe
    CYNTHIA SEARS; Fiscal Year: 2012
    ..and its biennial conference (founded in 1992) is to promote health and advance science through the study of anaerobic bacteria and their environments...
  15. Randomized Trial/Reduce Recurrence/Bacterial Vaginosis
    King Holmes; Fiscal Year: 2004
    ..Clinical trials of treating male partners of women with BV targeting anaerobic bacteria have not reduced the risk of BV recurrence...
  16. Adherent Invasive E. coli and colitis
    ANDREAS J BAUMLER; Fiscal Year: 2013
    ..by applicant): The human large intestine is host to a complex microbial community dominated by obligate anaerobic bacteria. However, conditions of intestinal inflammation lead to an increased relative abundance of facultative ..
  17. Peptides surface modification to prevent stent blockage
    Joseph Leung; Fiscal Year: 2006
    ..This is attributed to enzymatic activities of aerobic bacteria such as E. coli and anaerobic bacteria such as C. perfringens...
  18. Anaerobic Bacteria as Oncopathic Agents for Pancreatic Cancer
    Savio Woo; Fiscal Year: 2009
    ..also contain regions that are relatively well-vascularized and oxygenated, and hence refractory to the anaerobic bacteria treatment...
  19. QTRAP 5500 Triple Quadrupole Mass Spectrometer System
    Ruth Hogue Angeletti; Fiscal Year: 2010
    ..of new drugs for malaria and cancer, predictors for head and neck cancer outcome and therapy, metabolism of anaerobic bacteria, pathophysiology of impaired glucose tolerance, pharmacokinetics, and end stage renal disease...
  20. Biosynthesis and Physiology of Vitamin B12 in Prokaryotes
    MICHIKO TAGA; Fiscal Year: 2009
    ..However, a separate DMB biosynthetic pathway that does not use FMN as a precursor exists in anaerobic bacteria, and the enzymes involved in this pathway have not been identified...
  21. ANAEROBIC METABOLISM OF MUTAGENS IN HUMAN FOODS
    David Kingston; Fiscal Year: 1990
    ..The colonic microflora consists primarily of obligately anaerobic bacteria possessing extremely diverse metabolic capabilities...
  22. Analyses of Host-Biofilm Interactions: A Novel Polymicrobial Model
    Karen Novak; Fiscal Year: 2009
    ..middle colonizers) with subsequent colonization predominated by Gram-negative, anaerobic bacteria (late colonizers)...
  23. PRODUCTION OF URSODIOL FROM TURKEY BILE
    Tibor Sipos; Fiscal Year: 1991
    ..The specific aims of this Phase I proposal are to: 1. Screen known aerobic and anaerobic bacteria for their ability to convert chenodiol to ursodiol. 2...
  24. RAPID KINETIC AND OTHER STUDIES OF BIOLOGICAL OXYGENASES
    David Ballou; Fiscal Year: 2002
    ..3) A collaborative study with S. Ragsdale on acetyl-CoA biosynthesis in anaerobic bacteria. This system consists of a series of enzymes with cobalamin, nickel, and iron-sulfur centers...
  25. Therapy and Prevention for Bacterial Vaginosis
    Jane Schwebke; Fiscal Year: 2006
    Bacterial vaginosis (BV) is a sexually associated disease caused by a complex mixture or anaerobic bacteria. BV is the most prevalent cause of symptomatic vaginal discharge in the U.S...
  26. EFFECT OF ANTAGONISM AND S-IGA INDIGENOUS ANAEROBES
    RODNEY BERG; Fiscal Year: 1980
    ..determine whether or not specific local immunity reduces the population levels of certain oxygen-sensitive anaerobic bacteria in the mouse GI tract...
  27. Anaerobic Mobilization Technology for Remediation of Lo*
    FREDERIC PFAENDER; Fiscal Year: 2003
    ..It appears that under high-reducing conditions, a community of anaerobic bacteria utilize the hydrogen ions in solution as electron donors, raising the pH of the soil...
  28. RAPID STERILIZATION USING COLD MICROWAVE PLASMA JET
    OLIVIER POSTEL; Fiscal Year: 2000
    ..with injected air, generates oxygen and hydroxyl radicals which can be lethal to many types of aerobic and anaerobic bacteria smeared on glass slides...
  29. Silver Encapsulated Magnetic Nanoparticles for Pathogen Inactivation in Platelets
    SEASON WONG; Fiscal Year: 2007
    ..blood platelets and broth have shown that both Gram positive and negative bacteria as well as aerobic and anaerobic bacteria can be inactivated. According to the National Blood Data Resource Center, about 13...
  30. ACETOGENIC AUTOTROPHY AND METABOLISM OF NICKEL
    HAROLD DRAKE; Fiscal Year: 1990
    Nickel is a biologically active trace metal important to mammalian health, as are numerous obligately anaerobic bacteria which inhabit the microintestinal environment...
  31. Anaerobic Bacteria as Therapeutic Agents for Metastatic Cancer
    Savio Woo; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  32. Role of propionibacteria in sarcoidosis
    Stephen Tilley; Fiscal Year: 2005
    ..Several lines of evidence suggest that this anaerobic bacteria may be involved in the pathogenesis of disease...
  33. A Novel Regulator of Oxygen Homeostasis
    Frank Lee; Fiscal Year: 2009
    ..IOP1 binds to PHD2 and is homologous to hydrogenases, iron-containing enzymes with ancestral origins in anaerobic bacteria. Bacterial hydrogenases play central roles in maintaining redox balance under anaerobic conditions...
  34. Viral Infection in Lactobacilli: An Animal BV Model
    Lin Tao; Fiscal Year: 2004
    ..During BV, a shift in microbial dominance occurs-lactobacilli decrease while Gardnerrella vaginalis and anaerobic bacteria increase It is unknown, however, what triggers the shift in vaginal ecology to cause BV...
  35. SYNTHESIS OF MACROCYCLIC ANTITUMOR ANTIBIOTICS
    James Marshall; Fiscal Year: 1991
    ..Kijanimicin shows activity against anaerobic bacteria and acts as an antimalarial in mice...
  36. A NEW METHOD FOR SURFACE GROWTH OF ANAEROBIC BACTERIA
    JAMES COPELAND; Fiscal Year: 1990
    ..culture dishes that incorporate an oxygen reducing enzyme system, Oxyrase(tm), for the purpose of growing anaerobic bacteria. This Oxyrase culture dish will permit the reliable, rapid, and convenient observations of clinically ..
  37. Risk Factors and Outcomes of Candidemia in Children
    Theoklis Zaoutis; Fiscal Year: 2009
    ..This specific aim hypothesizes that the use of antibiotics with activity against anaerobic bacteria is associated with an increased risk of candidemia...
  38. A NEW METHOD FOR SURFACE GROWTH OF ANAEROBIC BACTERIA
    JAMES COPELAND; Fiscal Year: 1993
    ..This increased efficiency, together with elimination of special equipment supplies, will reduce the cost of working with anaerobic pathogens...
  39. High-throughput Drug Screen Against Botulinum Neurotoxin
    George Green; Fiscal Year: 2007
    b>Anaerobic bacteria of the genus Clostridium secrete seven botulinum neurotoxin (BoNT) serotypes (A-G), which enter human neuronal cells and destroy proteins essential for synaptic vesicle fusion to the presynaptic membrane...
  40. INTERCONCEPTIONAL ANTIBIOTICS TO PREVENT PRETERM BIRTH
    William Andrews; Fiscal Year: 2000
    ..urealyticum, mycoplasma, aerobic or anaerobic bacteria, or histologic endometrial inflammation during the interpregnancy interval compared to non-pregnant women ..
  41. Oral Immunology/Microbiology Research Group Annual Mtg
    Daniel Fine; Fiscal Year: 2003
    ..Perpetuation of the OIMRG and its annual meetings greatly enhances the spirit of collegial interaction/collaboration among investigators with expertise in immunology and microbial pathogenesis as related to oral health and disease. ..
  42. Attachment of Oral Actinobacillus to Epithelium
    Daniel Fine; Fiscal Year: 2008
    ..The longterm goal of this application is to use this information to identify targets for therapeutic agents that can interfere with attachment of Aa to oral tissues and thus prevent colonization leading to LAP. [unreadable] [unreadable]..
  43. Oral Immunology/Microbiology Annual Meeting
    Daniel Fine; Fiscal Year: 2003
    ..Perpetuation of the OIMRG and its annual meetings greatly enhances the spirit of collegial interaction/collaboration among investigators with expertise in immunology and microbial pathogenesis as related to oral health and disease. ..
  44. Microbial Markers for Periodontal Disease in Children
    Daniel Fine; Fiscal Year: 2005
    ....
  45. Efficient Mechanism of Gene Transfer in B. fragilis
    David Hecht; Fiscal Year: 2006
    ..abstract_text> ..
  46. ANTIBIOTIC RESISTANCE IN A SUBGINGIVAL BIOFILM MODEL
    Clay Walker; Fiscal Year: 2006
    ..We believe the information derived from the experiments described will provide a better understanding of the subgingival flora and the effects that antibiotics may have on this flora. ..
  47. Guided Pocket Recolonization (GPR) in Periodontitis
    Marc Quirynen; Fiscal Year: 2004
    ..Clinical data will be collected after 2, 4, 6, 8 and 12 weeks. The results should indicate the possible role for commensal organisms in periodontal disease and subgingival biofilm formation. ..
  48. Inhibitors of 5alpha-reductase for acne therapy
    Lingna Li; Fiscal Year: 2002
    ..PROPOSED COMMERCIAL APPLICATIONS: Liposomal 4-MA will be developed as a topical selectively targeted therapeutic for acne for which they should be a very market. ..
  49. RHOMOCYCSTEINASE FOR HOMOCYSTEINE ASSAY
    Yuying Tan; Fiscal Year: 2002
    ..The tHCY enzymatic kits for these applications will be ready for commercial launch at this point. PROPOSED COMMERCIAL APPLICATION: Not Available ..
  50. Discovery of novel fluorescent reporter genes
    Ming Zhao; Fiscal Year: 2004
    ..Reporters with spectral properties that can be used for whole-body imaging of tumors in the lung and their metastases will be candidates for further development for numerous applications of multi-color imaging. ..
  51. Imageable tumor-targeting bacteria
    Ming Zhao; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  52. Targeted tumoricidal bacteria
    Ming Zhao; Fiscal Year: 2007
    ..The resulting tumor killing was at best limited since anaerobic bacteria could not grow in viable tumor tissue...
  53. Dual-color tumor-host imaging models
    Meng Yang; Fiscal Year: 2007
    ..These models have significant commercial potential for discovery and development of stroma-targeted and anti-angiogenesis drugs. [unreadable] [unreadable] [unreadable]..
  54. Therapeutic hair follicle-derived neurospheres
    Meng Yang; Fiscal Year: 2007
    ..Human hair- follicle bulge cells will be further characterized and developed for therapeutic potential for nerve regeneration in Phase III. [unreadable]..
  55. Orthotopic models of tumor angiogenesis and blood flow
    Meng Yang; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  56. Adenoviral GFP targeting of metastatic human tumors using multiple delivery route
    Hiroyuki Kishimoto; Fiscal Year: 2008
    ..Having obtained these results, we can move forward in the Phase II grant application with experiments to bring OBP-401 to the clinic for use in cancer surgery in human patients. [unreadable] [unreadable] [unreadable]..
  57. Impact of Social Stress on TLR4-Induced Microbicidal Activity of CD11b+ Cells
    Michael Bailey; Fiscal Year: 2008
    ..Defining the stress-induced cellular changes that enhance immune functioning could stimulate new therapeutic approaches to treating infectious diseases. [unreadable] [unreadable] [unreadable] [unreadable]..