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| sarcocystisSummarySummary: A genus of protozoa found in reptiles, birds, and mammals, including humans. This heteroxenous parasite produces muscle cysts in intermediate hosts such as domestic herbivores (cattle, sheep, pigs) and rodents. Final hosts are predators such as dogs, cats, and man. Top Publications
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Blood clotting disorders during experimental sarcocystiosis in calvesA Daugschies
Institut für Parasitologie, Tierarztliche Hochschule Hannover, Germany
Int J Parasitol 28:1187-94. 1998The effects of experimental infection of calves with Sarcocystis cruzi on the blood coagulation cascade were investigated. Calves were inoculated orally with 1 x 10(5) sporocysts (group S1, n = 6) or with 5 x 10(5) sporocysts of S...
Epidemiology of Sarcocystis neurona infections in domestic cats (Felis domesticus) and its association with equine protozoal myeloencephalitis (EPM) case farms and feral cats from a mobile spay and neuter clinicJ F Stanek
Department of Veterinary Preventive Medicine, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210-1092, USA
Vet Parasitol 117:239-49. 2003Equine protozoal myeloencephalitis (EPM) is a serious neurologic disease in the horse most commonly caused by Sarcocystis neurona. The domestic cat (Felis domesticus) is an intermediate host for S. neurona...
Prevalence of antibodies to Neospora caninum, Sarcocystis neurona, and Toxoplasma gondii in wild horses from central WyomingJ P Dubey
Animal Parasitic Diseases Laboratory, Animal and Natural Resources Institute, Agricultural Research Service, United States Department of Agriculture, Building 1001, Beltsville, Maryland 20705 2350, USA
J Parasitol 89:716-20. 2003b>Sarcocystis neurona, Neospora caninum, N. hughesi, and Toxoplasma gondii are 4 related coccidians considered to be associated with encephalomyelitis in horses. The source of infection for N...
Seroprevalence of Neospora, Toxoplasma gondii and Sarcocystis neurona antibodies in horses from Jeju island, South KoreaG D Gupta
Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Connaway Hall, 1600 East Rollins Dr, Columbia, MO 65211, USA
Vet Parasitol 106:193-201. 2002..gondii equid (pony) were used. In addition, all samples were tested for antibodies to Sarcocystis neurona by immunoblot analysis. A total of 191 serum samples from clinically normal horses were evaluated...
Sarcocystis spp. in human infectionsRonald Fayer
U S Department of Agriculture, Agricultural Research Service, Animal and Natural Resources Institute, Environmental Microbial Safety Laboratory, Beltsville, MD 20705, USA
Clin Microbiol Rev 17:894-902, table of contents. 2004b>Sarcocystis species are intracellular protozoan parasites with an intermediate-definitive host life cycle based on a prey-predator relationship...
Self-mating in the definitive host potentiates clonal outbreaks of the apicomplexan parasites Sarcocystis neurona and Toxoplasma gondiiJered M Wendte
Molecular Parasitology Unit, Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
PLoS Genet 6:e1001261. 2010Tissue-encysting coccidia, including Toxoplasma gondii and Sarcocystis neurona, are heterogamous parasites with sexual and asexual life stages in definitive and intermediate hosts, respectively. During its sexual life stage, T...
Expression, purification, and biochemical characterization of a recombinant lectin of Sarcocystis muris (Apicomplexa) cyst merozoitesH Klein
Paul Ehrlich Institut, Federal Agency for Sera and Vaccines, FG Parasitologie Diagnostika, Langen, Germany
Glycoconj J 15:147-53. 1998The mature major microneme protein of Sarcocystis muris cyst merozoites, which is known as a dimeric lectin with high affinity to galactose and some of its derivatives, was expressed in Escherichia colias a histidine-tagged fusion ..
Prevalence of Neospora hughesi and Sarcocystis neurona antibodies in horses from various geographical locationsD Vardeleon
Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia 65211, USA
Vet Parasitol 95:273-82. 2001..In addition, all samples were tested for antibodies to Sarcocystis neurona by immunoblot analysis. A total of 208 samples was evaluated...
Immunohistochemical localisation of 3beta-hydroxysteroid dehydrogenase in Sarcocystis sppMurat Yarim
Department of Pathology, Faculty of Veterinary Medicine, University of Kirikkale, Yahsihan, Turkey
Parasitol Res 93:457-60. 2004..In the present study, 3beta-HSD was detected in the bradyzoites enclosed in sarcocysts of Sarcocystis spp. with immunohistochemistry...
Prey choice and habitat use drive sea otter pathogen exposure in a resource-limited coastal systemChristine K Johnson
Wildlife Health Center, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Proc Natl Acad Sci U S A 106:2242-7. 2009..sea otters and evaluated infection with 2 disease-causing protozoal pathogens, Toxoplasma gondii and Sarcocystis neurona, to reveal risks that increased the likelihood of pathogen exposure...
Experimental induction of the two-host life cycle of Sarcocystis cruzi between dogs and Korean native calvesS H Wee
National Veterinary Research and Quarantine Service, MAF, Anyang 430 824
Korean J Parasitol 39:227-32. 2001Eight dogs were experimentally infected with Sarcocystis by oral inoculation of cardiac muscle from naturally infected cattle...
Sarcocystis neurona: molecular characterization of enolase domain I region and a comparison to other protozoaK E Bolten
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon Tharp Street, Columbus, OH 43210, USA
Exp Parasitol 120:108-12. 2008b>Sarcocystis neurona causes protozoal myeloencephalitis and has the ability to infect a wide host range in contrast to other Sarcocystis species. In the current study, five S...
Clinical Sarcocystis neurona encephalomyelitis in a domestic cat following routine surgeryJ P Dubey
Parasite Biology, Epidemiology and Systematics Laboratory, Agricultural Research Service, US Department of Agriculture, Animal and Natural Resources Institute, Beltsville Agricultural Research Center, MD 20705 2350, USA
Vet Parasitol 112:261-7. 2003b>Sarcocystis neurona is an important cause of equine protozoal myeloencephalitis (EPM) in horses in the Americas...
Horses experimentally infected with Sarcocystis neurona develop altered immune responses in vitroSharon G Witonsky
Department of Large Animal Clinical Sciences, Phase II, Duck Pond Dr, Virginia Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, Virginia 24061 0442, USA
J Parasitol 94:1047-54. 2008Equine protozoal myeloencephalitis (EPM) due to Sarcocystis neurona infection is 1 of the most common neurologic diseases in horses in the United States...
Sarcocystis neurona merozoites express a family of immunogenic surface antigens that are orthologues of the Toxoplasma gondii surface antigens (SAGs) and SAG-related sequencesDaniel K Howe
Department of Veterinary Science, 108 Gluck Equine Research Center, University of Kentucky, Lexington, KY 40546 0099, USA
Infect Immun 73:1023-33. 2005b>Sarcocystis neurona is a member of the Apicomplexa that causes myelitis and encephalitis in horses but normally cycles between the opossum and small mammals. Analysis of an S...
Surveillance of endoparasitic infections and the first report of Physaloptera sp. and Sarcocystis spp. in farm rodents and shrews in central TaiwanKwong Chung Tung
Department of Veterinary Medicine, College of Veterinary Medicine, National Chung Hsing University, 250 Kuo Kuuang Road, Taichung, Taiwan
J Vet Med Sci 71:43-7. 2009..1%), Syphacia muris (2.1%), Trichosomoides crassicauda (29.5%), and Trichurus sp. (1.1%), and one protozoan, Sarcocystis spp. (33.7%). Physaloptera sp. from S. murinus and Sarcocystis spp. from both R. norvegicus and R...
Protozoal meningoencephalitis in sea otters (Enhydra lutris): a histopathological and immunohistochemical study of naturally occurring casesN J Thomas
Department of the Interior, US Geological Survey, National Wildlife Health Center, Madison, WI, USA
J Comp Pathol 137:102-21. 2007..the actively multiplicative life stages of the organisms (tachyzoites for Toxoplasma gondii and merozoites for Sarcocystis neurona) and immunohistochemical labelling were used to identify infection with S. neurona (n=22, 56.4%), T...
Corvid birds (Corvidae) act as definitive hosts for Sarcocystis ovalis in moose (Alces alces)Bjørn Gjerde
Department of Food Safety and Infection Biology, Section of Microbiology, Immunology and Parasitology, Norwegian School of Veterinary Science, P O Box 8146 Dep, 0033, Oslo, Norway
Parasitol Res 107:1445-53. 2010Epidemiological data and a unique phylogenetic position had suggested that Sarcocystis ovalis in moose and red deer might use a definitive host other than canids, felids, or humans...
Prevalence of antibodies to Sarcocystis neurona, Toxoplasma gondii and Neospora caninum in horses from ArgentinaJ P Dubey
Parasite Biology and Epidemiology Laboratory, United States Department of Agriculture, Agricultural Research Service, Livestock and Poultry Sciences Institute, Beltsville, MD 20705 2350, USA
Vet Parasitol 86:59-62. 1999Sera from 76 horses from Argentina were examined for antibodies to Sarcocystis neurona, Toxoplasma gondii and Neospora caninum. Antibodies to S. neurona were found in 27 (35...
Characterization of a serine protease activity in Sarcocystis neurona merozoitesS C Barr
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA
J Parasitol 89:385-8. 2003b>Sarcocystis neurona merozoites were examined for their ability to invade and divide in bovine turbinate (BT) cell cultures after treatment with cysteine (iodoacetamide), aspartic (pepstatin A), metallo-(1,10-phenanthroline and ethylene ..
Sarcocystis lindsayi n. sp. (Protozoa: Sarcocystidae) from the South American opossum, Didelphis albiventris from BrazilJ P Dubey
United States Department of Agriculture, Agricultural Research Service, Animal and Natural Resources Institute, Parasite Biology, Epidemiology and Systematics Laboratory, Beltsville, Maryland 20705 2350, USA
J Eukaryot Microbiol 48:595-603. 2001A new species, Sarcocystis lindsayi n. sp., is proposed for a parasite resembling Sarcocystis falcatula...
New comprehension of the apicoplast of Sarcocystis by transmission electron tomographyCveta Tomova
, , Helmholtzstrasse 10, D-01062 Dresden, Germany
Biol Cell 98:535-45. 2006BACKGROUND INFORMATION: Apicomplexan parasites (like Plasmodium, Toxoplasma, Eimeria and Sarcocystis) contain a distinctive organelle, the apicoplast, acquired by a secondary endosymbiotic process analogous to chloroplasts and ..
A novel Sarcocystis-associated encephalitis and myositis in racing pigeonsP Olias
Department of Veterinary Pathology, Freie Universitat Berlin, Robert von Ostertag Strasse 15, Berlin, Germany
Avian Pathol 38:121-8. 2009..domestica) have previously been attributed to infection with Sarcocystis falcatula, which is shed in the faeces of the opossum (Didelphis virginiana)...
Eosinophilic myositis due to Sarcocystis hominis in a beef cowW Wouda
Animal Health Service Ltd, Post Box 9, 7400 AA Deventer, The Netherlands
J Comp Pathol 135:249-53. 2006..By transmission electron microscopy the sarcocysts were identified as Sarcocystis hominis, based on the morphology of villar protrusions of the sarcocyst wall, which were broad-based and ..
Characterization of Sarcocystis from four species of hawks from Georgia, USAMichael J Yabsley
Daniel B Warnell School of Forestry and Natural Resources, University of Georgia, Athens, Georgia 30602, USA
J Parasitol 95:256-9. 2009During 2001 to 2004, 4 species of hawks (Buteo and Accipiter spp.) from Georgia were surveyed for Sarcocystis spp. infections by examining intestinal sections. In total, 159 of 238 (66...
Ultrastructural and molecular confirmation of the development of Sarcocystis neurona tissue cysts in the central nervous system of southern sea otters (Enhydra lutris nereis)M A Miller
Marine Wildlife Veterinary Care and Research Center, California Department of Fish and Game, 1451 Shaffer Road, Santa Cruz, CA 95060, USA
Int J Parasitol 39:1363-72. 2009In 2004, three wild sea otters were diagnosed with putative Sarcocystis neurona-associated meningoencephalitis by histopathology and immunohistochemistry...
Limited genetic diversity among Sarcocystis neurona strains infecting southern sea otters precludes distinction between marine and terrestrial isolatesJ M Wendte
Molecular Parasitology Unit, Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 0425, USA
Vet Parasitol 169:37-44. 2010b>Sarcocystis neurona is an apicomplexan parasite identified as a cause of fatal neurological disease in the threatened southern sea otter (Enhydra lutris nereis). In an effort to characterize virulent S...
Brown-headed cowbirds (Molothrus ater) harbor Sarcocystis neurona and act as intermediate hostsL S Mansfield
Departments of Large Animal Clinical Sciences and Microbiology and Molecular Genetics, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA
Vet Parasitol 153:24-43. 2008We tested the hypothesis that brown-headed cowbirds (Molothrus ater) harbor Sarcocystis neurona, the agent of equine protozoal myeloencephalitis (EPM), and act as intermediate hosts for this parasite...
Reduction of transmission stages concomitant with increased host immune responses to hypervirulent Sarcocystis singaporensis, and natural selection for intermediate virulenceT Jakel
Division of Parasitology, Department of Zoology, University of Hohenheim, Emil Wolff Strasse 34, 70599 Stuttgart, Germany
Int J Parasitol 31:1639-47. 2001..depending on inoculum size) and host immune reactions were examined for the apicomplexan protozoan Sarcocystis singaporensis...
Experimental inoculation of domestic cats (Felis domesticus) with Sarcocystis neurona or S. neurona-like merozoitesM Butcher
College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
Vet Parasitol 107:1-14. 2002b>Sarcocystis neurona is the parasite most commonly associated with equine protozoal myeloencephalitis (EPM). Recently, cats (Felis domesticus) have been demonstrated to be an experimental intermediate host in the life cycle of S. neurona...
Modest genetic differentiation among North American populations of Sarcocystis neurona may reflect expansion in its geographic rangeN Sundar
United States Department of Agriculture, Agricultural Research Service, Animal Natural Resources Institute, Animal Parasitic Diseases Laboratory, Beltsville, MD 20705 2350, USA
Vet Parasitol 152:8-15. 2008b>Sarcocystis neurona is an important cause of neurological disease in horses (equine protozoal myeloencephalitis, EPM) and sea otters in the United States...
A protozoal-associated epizootic impacting marine wildlife: mass-mortality of southern sea otters (Enhydra lutris nereis) due to Sarcocystis neurona infectionMelissa A Miller
Marine Wildlife Veterinary Care and Research Center, Santa Cruz, CA 95060, USA
Vet Parasitol 172:183-94. 2010..lesions consistent with an infectious etiology, and further investigation confirmed the protozoan parasite Sarcocystis neurona as the underlying cause. Tissues from 94% of examined otters were PCR-positive for S...
Molecular characterization of Sarcocystis neurona strains from opossums (Didelphis virginiana) and intermediate hosts from Central CaliforniaDaniel Rejmanek
Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA
Vet Parasitol 170:20-9. 2010b>Sarcocystis neurona is a significant cause of neurological disease in horses and other animals, including the threatened Southern sea otter (Enhydra lutris nereis). Opossums (Didelphis virginiana), the only known definitive hosts for S...
A review of Sarcocystis neurona and equine protozoal myeloencephalitis (EPM)J P Dubey
United States Department of Agriculture, Agricultural Research Service, Animal and Natural Resources Institute, Beltsville Agricultural Research Center, MD 20705 2350, USA
Vet Parasitol 95:89-131. 2001..The protozoan most commonly associated with EPM is Sarcocystis neurona. The complete life cycle of S...
A genetically diverse but distinct North American population of Sarcocystis neurona includes an overrepresented clone described by 12 microsatellite allelesIngrid M Asmundsson
Animal Parasitic Disease Laboratory, Animal and Natural Resources Institute, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, USA
Infect Genet Evol 6:352-60. 2006..true for tissue-cyst forming coccidia, and to address evolutionary and taxonomic problems within the genus Sarcocystis, we characterized polymorphic microsatellite markers in Sarcocystis neurona, the major causative agent of ..
Mapping of quantitative trait loci affecting resistance/susceptibility to Sarcocystis miescheriana in swineGerald Reiner
Department of Veterinary Clinical Sciences, University of Giessen, D 35392 Giessen, Germany
Genomics 89:638-46. 2007..In swine, e.g., marked differences in resistance/susceptibility to Sarcocystis miescheriana have been shown between Chinese Meishan and European Pietrain pigs, and these differences are ..
Plastid segregation and cell division in the apicomplexan parasite Sarcocystis neuronaShipra Vaishnava
Department of Cellular Biology, University of Georgia, Athens, GA 30602, USA
J Cell Sci 118:3397-407. 2005..We have studied the replication and segregation of this important organelle using the parasite Sarcocystis neurona as a cell biological model...
Genetic variation among isolates of Sarcocystis neurona, the agent of protozoal myeloencephalitis, as revealed by amplified fragment length polymorphism markersH M Elsheikha
Department of Large Animal Clinical Sciences, Michigan State University, East Lansing, MI 48824, USA
Infect Immun 74:3448-54. 2006b>Sarcocystis neurona causes serious neurological disease in horses and other vertebrates in the Americas. Based on epidemiological data, this parasite has recently emerged...
Analysis of the Sarcocystis neurona microneme protein SnMIC10: protein characteristics and expression during intracellular developmentJessica S Hoane
Department of Veterinary Science, University of Kentucky, 108 Gluck Equine Research Center, Lexington, KY 40546 0099, USA
Int J Parasitol 33:671-9. 2003b>Sarcocystis neurona, an apicomplexan parasite, is the primary causative agent of equine protozoal myeloencephalitis. Like other members of the Apicomplexa, S...
Toxoplasma gondii, Neospora caninum, Sarcocystis neurona, and Sarcocystis canis-like infections in marine mammalsJ P Dubey
United States Department of Agriculture, Agricultural Research Service, Animal and Natural Resources Institute, Animal Parasitic Diseases Laboratory, Beltsville, MD 20705 2350, USA
Vet Parasitol 116:275-96. 2003Toxoplasma gondii, Neospora caninum, Sarcocystis neurona, and S. canis are related protozoans that can cause mortality in many species of domestic and wild animals. Recently, T. gondii and S...
In vitro efficacy of nitro- and halogeno-thiazolide/thiadiazolide derivatives against Sarcocystis neuronaG Gargala
Parasitology Department, University of Rouen, France
Vet Parasitol 162:230-5. 2009b>Sarcocystis neurona is an obligate intracellular parasite that causes equine protozoal myeloencephalitis (EPM)...
Cell-mediated immune responses in horses with equine protozoal myeloencephalitisJennifer A Spencer
Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, Alabama 36849, USA
J Parasitol 90:428-30. 2004..myeloencephalitis (EPM) is a neurologic syndrome seen in horses from the Americas and is mainly caused by Sarcocystis neurona...
First case report of Sarcocystis neurona-induced equine protozoal myeloencephalitis in JapanYoshinari Katayama
Epizootic Research Station, Equine Research Institute, Japan Racing Association, Tochigi, Japan
J Vet Med Sci 65:757-9. 2003..Immunohistochemically, shizonts were occasionally observed and were positive for anti-Sarcocystis neurona (S. neurona) antiserum. S...
Evaluation of immune responses in horses immunized using a killed Sarcocystis neurona vaccineAntoinette E Marsh
Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
Vet Ther 5:34-42. 2004Clinically normal horses developed cellular immunity to Sarcocystis neurona following IM vaccination with a commercial killed S. neurona vaccine, as indicated by the development of measurable anti-S...
Effect of a single dose of ponazuril on neural infection and clinical disease in Sarcocystis neurona-challenged interferon-gamma knockout miceRobert P Franklin
Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, 2015 SW 16th Ave, Gainesville, FL 32610, USA
Vet Parasitol 114:123-30. 2003Interferon gamma-knockout mice were challenged with 5000 Sarcocystis neurona sporocysts acquired from a naturally infected opossum. Ponazuril was administered once, by gavage, at day 1, 3, 7, 10, or 14 post-infection (pi)...
Assessing the agreement of Western blot test results for paired serum and cerebrospinal fluid samples from horses tested for antibodies to Sarcocystis neuronafM G Rossano
The Population Medicine Center, A 59 Veterinary Medical Center, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA
Vet Parasitol 115:233-8. 2003..EPM) is a neurological disease of equids that is caused by infection of the central nervous system with Sarcocystis neurona...
Protective immune response to experimental infection with Sarcocystis neurona in 57BL/6 miceSharon G Witonsky
Department of Large Animal Clinical Sciences, Virginia Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University Virginia Tech Blacksburg, Virginia 24061 0442, USA
J Parasitol 89:924-31. 2003Immunocompetent C57BL/6 mice were infected with Sarcocystis neurona merozoites to assess the protective immune response to active infection. Using a direct agglutination test, all infected mice seroconverted to S...
Evaluation and comparison of an indirect fluorescent antibody test for detection of antibodies to Sarcocystis neurona, using serum and cerebrospinal fluid of naturally and experimentally infected, and vaccinated horsesPaulo C Duarte
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, One Shields Avenue, Davis, California 95616, USA
J Parasitol 90:379-86. 2004..test (IFAT) using serum and cerebrospinal fluid (CSF) of horses naturally and experimentally infected with Sarcocystis neurona, to assess the correlation between serum and CSF titers, and to determine the effect of S...
Sarcocystis neurona (Protozoa: Apicomplexa): description of oocysts, sporocysts, sporozoites, excystation, and early developmentDavid S Lindsay
Department of Biomedical Sciences and Pathobiology, Virginia Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, 24061 0342, USA
J Parasitol 90:461-5. 2004..Horses are considered accidental intermediate hosts. The structure of sporocysts of the causative agent, Sarcocystis neurona, has never been described. Sporocysts of S...
Clinical Sarcocystis neurona, Sarcocystis canis, Toxoplasma gondii, and Neospora caninum infections in dogsJ P Dubey
United States Department of Agriculture, Agricultural Research Service, Animal and Natural Resources Institute, Animal Parasitic Diseases Laboratory, Beltsville Agricultural Research Center, Beltsville, MD 20705 2350, USA
Vet Parasitol 137:36-49. 2006b>Sarcocystis neurona, Sarcocystis canis, Toxoplasma gondii, and Neospora caninum are related apicomplexans that can cause systemic illness in many species of animals, including dogs...
Increased presence of T lymphocytes in central nervous system of EPM affected horsesPatricia Scott
Department of Large Animal Clinical Sciences, Virginia Polytechnic Institute and State University, Blacksburg 24061-0442, USA
J Parasitol 91:1499-502. 2005Equine protozoal myeloencephalitis (EPM), caused by Sarcocystis neurona infection in the central nervous system (CNS), affects up to 1% of all horses during their lifetimes...
Immune response to Sarcocystis neurona infection in naturally infected horses with equine protozoal myeloencephalitisJibing Yang
Department of Large Animal Clinical Sciences, Phase II, Duck Pond Dr, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, 24061, USA
Vet Parasitol 138:200-10. 2006..The primary etiologic agent is Sarcocystis neurona...
Investigation of SnSPR1, a novel and abundant surface protein of Sarcocystis neurona merozoitesDeqing Zhang
Department of Veterinary Sciences, University of Kentucky, Gluck Equine Research Center, Lexington, KY 40546 0099, USA
Vet Parasitol 152:210-9. 2008..sequence tag (EST) sequencing project has produced over 15,000 partial cDNA sequences from the equine pathogen Sarcocystis neurona...
Persistence of serum antibodies to Sarcocystis neurona in horses moved from North America to IndiaChristopher M Brown
Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Canada
J Vet Intern Med 20:994-7. 2006The study reported here was undertaken to assess the presence of antibodies to Sarcocystis neurona in the serum of horses of North American origin that had been relocated for 1 year or more to India (ie, outside of the known endemic ..
Diagnosis of Sarcocystis cruzi, Neospora caninum, and Toxoplasma gondii infections in cattleG More
Laboratorio de Inmunoparasitologia, Cátedra de Parasitología y Enfermedades Parasitarias, Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, 60 y 118, 1900 La Plata, Argentina
Parasitol Res 102:671-5. 2008The aim of the study was to diagnose Sarcocystis sp. infections in cattle and to detect coinfections by Toxoplasma gondii and/or Neospora caninum...
Early migration of Sarcocystis neurona in ponies fed sporocystsE Elitsur
Department of Veterinary Preventive Medicine, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio 43210 1092, USA
J Parasitol 93:1222-5. 2007b>Sarcocystis neurona is the most important cause of equine protozoal myeloencephalitis (EPM), a neurologic disease of the horse. In the present work, the kinetics of S. neurona invasion is determined in the equine model...
Antibody index and specific antibody quotient in horses after intragastric administration of Sarcocystis neurona sporocystsKatherine A Heskett
Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
Am J Vet Res 69:403-9. 2008To investigate the use of a specific antibody index (AI) that relates Sarcocystis neurona-specific IgG quotient (Q(SN)) to total IgG quotient (Q(IgG)) for the detection of the anti-S neurona antibody fraction of CNS origin in CSF samples ..
Prevalence of Sarcocystis neurona and Neospora spp. infection in horses from Brazil based on presence of serum antibodies to parasite surface antigenJessica S Hoane
Department of Veterinary Science, University of Kentucky, 108 Gluck Equine Research Center, Lexington, KY 40546-0099, USA
Vet Parasitol 136:155-9. 2006..tested for antibodies against the major surface antigens SnSAG4 and NhSAG1 to determine the seroprevalence of Sarcocystis neurona and Neospora hughesi, respectively. Antibodies against SnSAG4 were detected in 669 (69...
Enzyme-linked immunosorbent assays for detection of equine antibodies specific to Sarcocystis neurona surface antigensJessica S Hoane
Department of Veterinary Science, University of Kentucky, Lexington, KY 40546-0099, USA
Clin Diagn Lab Immunol 12:1050-6. 2005b>Sarcocystis neurona is the primary causative agent of equine protozoal myeloencephalitis (EPM), a common neurologic disease of horses in the Americas...
Experimental infection of ponies with Sarcocystis fayeri and differentiation from Sarcocystis neurona infections in horsesW J A Saville
Department of Veterinary Preventive Medicine, College of Veterinary Medicine, Ohio State University, Columbus, Ohio 43210 1092, USA
J Parasitol 90:1487-91. 2004b>Sarcocystis neurona and Sarcocystis fayeri infections are common in horses in the Americas...
Assessment of Sarcocystis neurona sporocyst viability and differentiation between viable and nonviable sporocysts using propidium iodide stainHany M Elsheikha
Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan 48824, USA
J Parasitol 90:872-5. 2004b>Sarcocystis neurona has become recognized as the major causative agent of equine protozoal myeloencephalitis (EPM) in the Americas. At least 3 pathogenic species of Sarcocystis, including S. neurona, can be isolated from opossums...
Prevalence of agglutinating antibodies to Sarcocystis neurona in raccoons (Procyon lotor) from an urban area of VirginiaKatie Hancock
Center for Molecular Medicine and Infectious Diseases, Department of Biomedical Sciences and Pathobiology, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, 1410 Prices Fork Road, Blacksburg, Virginia 24061-0342, USA
J Parasitol 90:881-2. 2004..myeloencephalitis is the most important protozoan disease of horses in North America and is usually caused by Sarcocystis neurona. Natural and experimentally induced cases of encephalitis caused by S...
Infection of immunodeficient horses with Sarcocystis neurona does not result in neurologic diseaseDebra C Sellon
Department of Veterinary Clinical Sciences, Washington State University, Pullman, WA 99163, USA
Clin Diagn Lab Immunol 11:1134-9. 2004..is a progressive neurologic disease of horses most commonly caused by infection with the apicomplexan parasite Sarcocystis neurona. Factors affecting neuroinvasion and neurovirulence have not been determined...
Antigenic evaluation of a recombinant baculovirus-expressed Sarcocystis neurona SAG1 antigenG D Gupta
Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia, Missouri 65211, USA
J Parasitol 90:1027-33. 2004b>Sarcocystis neurona is the primary parasite associated with equine protozoal myeloencephalitis (EPM). This is a commonly diagnosed neurological disorder in the Americas that infects the central nervous system of horses...
Cross-sectional survey in pig breeding farms in Hesse, Germany: seroprevalence and risk factors of infections with Toxoplasma gondii, Sarcocystis spp. and Neospora caninum in sowsI M Damriyasa
Institute of Parasitology, Justus Liebig University Giessen, Rudolf-Buchheim-Strasse 2, 35392 Giessen, Germany
Vet Parasitol 126:271-86. 2004..survey was performed to estimate the prevalences of antibodies to Toxoplasma gondii (ELISA, IFAT), Sarcocystis spp. (ELISA, using S...
Parasitemia in an immunocompetent horse experimentally challenged with Sarcocystis neurona sporocystsM G Rossano
The Population Medicine Center, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA
Vet Parasitol 127:3-8. 2005..Most cases are attributed to infection of the central nervous system with Sarcocystis neurona...
Phylogenetic relationships of Sarcocystis neurona of horses and opossums to other cyst-forming coccidia deduced from SSU rRNA gene sequencesHany M Elsheikha
Department of Large Animal Clinical Sciences, Michigan State University, East Lansing, MI 48824, USA
Parasitol Res 97:345-57. 2005..subunit rRNA (ssurRNA) gene were performed to examine the origin, phylogeny, and biogeographic relationships of Sarcocystis neurona isolates from opossums and horses from the State of Michigan, USA, in relation to other cyst-forming ..
Risk of transplacental transmission of Sarcocystis neurona and Neospora hughesi in California horsesPaulo C Duarte
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, One Shields Avenue, Davis, California 95616, USA
J Parasitol 90:1345-51. 2004The study objective was to assess the risk of transplacental transmission of Sarcocystis neurona and Neospora hughesi in foals from 4 California farms during 3 foaling seasons...
What is your neurologic diagnosis? Equine protozoal myeloencephalitisLaura H Javsicas
Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
J Am Vet Med Assoc 232:201-4. 2008
Detection of Sarcocystis neurona antibodies in French horses with neurological signsP-H Pitel
Int J Parasitol 32:481-5. 2002
Effect of intermittent oral administration of ponazuril on experimental Sarcocystis neurona infection of horsesRobert J MacKay
Department of Large Animal Clinical Sciences, University of Florida, Gainesville, FL 32610, USA
Am J Vet Res 69:396-402. 2008To evaluate the effect of intermittent oral administration of ponazuril on immunoconversion against Sarcocystis neurona in horses inoculated intragastrically with S neurona sporocysts.
The seroprevalence of antibodies to Sarcocystis neurona in Michigan equidsM G Rossano
The Population Medicine Center, College of Veterinary Medicine, A-109 Veterinary Medical Center, Michigan State University, 48824-1314, East Lansing, MI, USA
Prev Vet Med 48:113-28. 2001A cross-sectional study of serum antibodies to Sarcocystis neurona (the etiologic agent of equine protozoal myeloencephalitis, EPM) was performed on Michigan equids. Our objectives were to determine the seroprevalence of antibodies to S...
Serologic responses of cats against experimental Sarcocystis neurona infectionsJ P Dubey
United States Department of Agriculture, Agricultural Research Service, Animal and Natural Resources Institute, Parasite Biology, Epidemiology and Systematics Laboratory, Building 1001, Beltsville, MD 20705 2350, USA
Vet Parasitol 107:265-9. 2002b>Sarcocystis neurona is the most important cause of a neurologic disease of horses, equine protozoal myeloencephalitis (EPM). Cats and other carnivores can act as its intermediate hosts and horses are aberrant hosts...
Sarcocystis neurona: parasitemia in a severe combined immunodeficient (SCID) horse fed sporocystsMaureen T Long
Department of Large Animal Clinical Sciences, University of Florida, Gainesville, FL 32610, USA
Exp Parasitol 100:150-4. 2002b>Sarcocystis neurona was isolated from the blood of a 5-month-old Arabian foal with severe combined immunodeficiency...
Clinical diagnosis of equine protozoal myeloencephalitis (EPM)Martin Furr
Marion duPont Scott Equine Medical Center, Virginia-Maryland Regional College of Veterinary Medicine, Leesburg, VA 20177, USA
J Vet Intern Med 16:618-21. 2002
Sensitivity and specificity of western blot testing of cerebrospinal fluid and serum for diagnosis of equine protozoal myeloencephalitis in horses with and without neurologic abnormalitiesBarbara M Daft
California Animal Health and Food Safety Laboratory System, School of Veterinary Medicine, University of California, Davis, San Bernardino 92408, USA
J Am Vet Med Assoc 221:1007-13. 2002..PROCEDURE: CSF and serum from horses submitted for necropsy were tested for Sarcocystis neurona-specific antibody with a WBT...
Mice lacking the gene for inducible or endothelial nitric oxide are resistant to sporocyst induced Sarcocystis neurona infectionsAlexa C Rosypal
Department of Biomedical Sciences and Pathobiology, Center for Molecular Medicine and Infectious Diseases, Virginia Maryland Regional College of Veterinary Medicine, 1410 Prices Fork Road, Blacksburg, VA 24061 0342, USA
Vet Parasitol 103:315-21. 2002..syndrome in horses from the Americas and is usually caused by infection with the apicomplexan parasite, Sarcocystis neurona. Little is known about the role of immunobiological mediators to this parasite...
Neurologic disease in gamma-interferon gene knockout mice caused by Sarcocystis neurona sporocysts collected from opossums fed armadillo muscleM A Cheadle
Department of Pathobiology, College of Veterinary Medicine, University of Florida, PO Box 110880, 2015 SW 16th Avenue, Gainesville, FL 32610 0880, USA
Vet Parasitol 103:65-9. 2002Fifteen gamma-interferon gene knockout mice were each orally inoculated with 5 x 10(3) Sarcocystis sporocysts derived from Virginia opossums (Didelphis virginiana) fed nine-banded armadillo (Dasypus novemcinctus) muscle containing ..
Evidence to support horses as natural intermediate hosts for Sarcocystis neuronaThomas Mullaney
Diagnostic Center for Population and Animal Health (DCPAH, College of Veterinary Medicine, Michigan State University (MSU, East Lansing, MI 48824, USA
Vet Parasitol 133:27-36. 2005Opossums (Didelphis spp.) are the definitive host for the protozoan parasite Sarcocystis neurona, the causative agent of equine protozoal myeloencephalitis (EPM)...
Comparison of a serum indirect fluorescent antibody test with two Western blot tests for the diagnosis of equine protozoal myeloencephalitisPaulo C Duarte
Department of Medicine and Epidemiology, School of Veterinary Medicine, One Shields Avenue, University of California, Davis, CA 95616-8737, USA
J Vet Diagn Invest 15:8-13. 2003..2% (72.6-95.7%), and 69.2% (52.4-83%), respectively. The overall accuracy of the IFAT was shown to be better than that of the WBs and, therefore, the test has potential for use in the diagnosis of EPM caused by Sarcocystis neurona.
Detection of antibodies against Sarcocystis neurona in cerebrospinal fluid from clinically normal neonatal foalsAnne Grimsley Cook
Department of Large Animal Clinical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Blacksburg, VA, USA
J Am Vet Med Assoc 220:208-11. 2002OBJECTIVE: To determine whether antibodies against Sarcocystis neurona could be detected in CSF from clinically normal neonatal (2 to 7 days old) and young (2 to 3 months old) foals. DESIGN: Prospective study...
Reduced levels of nitric oxide metabolites in cerebrospinal fluid are associated with equine protozoal myeloencephalitisChinedu J Njoku
Department of Veterinary Preventive Medicine, The Ohio State University, Columbus, Ohio 43210, USA
Clin Diagn Lab Immunol 9:605-10. 2002..EPM) is a disease of horses that is primarily associated with infection with the apicomplexan Sarcocystis neurona...
Effects of high temperature and disinfectants on the viability of Sarcocystis neurona sporocystsJ P Dubey
Parasite Biology, Epidemiology and Systematics Laboratory, Building 1001, Animal and Natural Resources Institute, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland 20705 2350, USA
J Parasitol 88:1252-4. 2002The effect of moist heat and several disinfectants on Sarcocystis neurona sporocysts was investigated...
Suspected protozoal myeloencephalitis in a two-month-old coltL C Gray
Veterinary Medical Teaching Hospital, Large Animal Clinic, Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis 95616, USA
Vet Rec 149:269-73. 2001..imaging (MRI), peripheral nerve biopsy, and Western blot analysis for the presence of intrathecal antibodies to Sarcocystis neurona, the causative agent of equine protozoal myeloencephalitis...
Life cycle of Sarcocystis neurona in its natural intermediate host, the raccoon, Procyon lotorJ F Stanek
Department of Veterinary Preventive Medicine, College of Veterinary Medicine, The Ohio State University, 1900 Coffey Road, Columbus, Ohio 43210-1092, USA
J Parasitol 88:1151-8. 2002b>Sarcocystis neurona causes encephalomyelitis in many species of mammals and is the most important cause of neurologic disease in the horse...
Reactivity against Sarcocystis neurona and Neospora by serum antibodies in healthy French horses from two farms with previous equine protozoal myeloencephalitis-like casesP H Pitel
, 1 Route de Rosel, Caen, France
Vet Parasitol 111:1-7. 2003b>Sarcocystis neurona is considered a leading cause of equine protozoal myeloencephalitis (EPM), a common infectious neurological disease in horses in the Americas. EPM-like cases associated with S...
Protozoan infections (Toxoplasma gondii, Neospora caninum and Sarcocystis spp.) in sheep and goats: recent advancesD Buxton
Division of Virology, Moredun Research Institute, International Research Centre, Scotland, UK
Vet Res 29:289-310. 1998..b>Sarcocystis, which exists as numerous species, undergoes a coccidian-like life cycle with each having a distinctive ..
The prevalence of intestinal parasites in dogs from Prague, rural areas, and shelters of the Czech RepublicS Dubná
Department of Zoology and Fisheries, Faculty of Agrobiology, Food and Natural Resources, Czech University of Agriculture in Prague, Kamycka 957, 165 21 Prague 6, Suchdol, Czech Republic
Vet Parasitol 145:120-8. 2007..1.1%), Taenia-type (1.0%), Giardia spp. (0.1%), Toxascaris sp. (0.9%), Dipylidium sp. (0.7%), Sarcocystis spp. (0.6%), Capillaria spp. (0.6%), Neospora/Hammondia spp. (0.5%), Ancylostoma sp. (0.4%), Uncinaria sp. (0...
Emerging food-borne parasitesP Dorny
Department of Animal Health, Institute of Tropical Medicine, B 2000 Antwerp, Belgium
Vet Parasitol 163:196-206. 2009..However, it is often not very sensitive, frequently not practised, and not done for T. gondii and Sarcocystis spp...
Prevalence of antibodies to Trypanosoma cruzi, Toxoplasma gondii, Encephalitozoon cuniculi, Sarcocystis neurona, Besnoitia darlingi, and Neospora caninum in North American opossums, Didelphis virginiana, from southern LouisianaAlice E Houk
Department of Biomedical Sciences and Pathobiology, Virginia Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, Virginia 24061 0342, USA
J Parasitol 96:1119-22. 2010..Toxoplasma gondii, and Encephalitozoon cuniculi) and protozoans of veterinary importance ( Neospora caninum, Sarcocystis neurona, and Besnoitia darlingi) in a population of North American opossums ( Didelphis virginiana) from ..
Six new species of coccidia (Apicomplexa: Eimeriidae) from endangered Phelsuma spp. geckoes (Sauria: Gekkonidae) of the Black River Gorges National Park, MauritiusPeter Daszak
Wildlife Trust, 460 West 34th Street, 17th Floor, New York, NY 10001, USA
Folia Parasitol (Praha) 56:233-41. 2009..cepediana. These oocysts or sporocysts are significantly larger than the Cryptosporidium species so far described from reptiles, and likely represent excretion of spuriously ingested sporocysts of a Sarcocystis or Adelina coccidian.
[The endoparasites of Sika deer (Cervus nippon) in Austria]Steffen Rehbein
Merial GmbH, Kathrinenhof Research Center, Rohrdorf, Deutschland
Wien Klin Wochenschr 119:96-101. 2007..In all, at least four species of protozoa (Eimeria austriaca, Eimeria robusta, Eimeria sordida; Sarcocystis spp...
Evaluation of commercial enzyme immunoassay (EIA) and immunofluorescent antibody (FA) test kits for detection of Cryptosporidium oocysts of species other than Cryptosporidium parvumT K Graczyk
Department of Molecular Microbiology and Immunology, School of Hygiene and Public Health, The Johns Hopkins University, Baltimore, Maryland, USA
Am J Trop Med Hyg 54:274-9. 1996..was no cross-reactivity of EIA with ova of eight medically important helminths, three Eimeria species oocysts, Sarcocystis cruzi sporocysts, and two Candida sp. isolates. All nine snake oocyst isolates (C...
[Current prevalence of toxocariasis and other intestinal parasitoses among dogs in Bratislava]A Totkova
Parazitologický ustav LF UK Bratislava
Epidemiol Mikrobiol Imunol 55:17-22. 2006..Giardia was the significantly most frequent genus among intestinal protozoans while Isospora, Sarcocystis and Cryptosporidium were considerably less common...
Parasites in cross-bred pigs in the Upper East region of GhanaA Permin
Danish Centre for Experimental Parasitology, The Royal Veterinary and Agricultural University, Frederiksberg C, Denmark
Vet Parasitol 87:63-71. 1999..7% of the animals. Small pieces of the diaphragm were examined for the presence of Sarcocystis spp.. The prevalence was 28.3%, but no larvae of Trichinella spp. were found...
[Formation and diversity of parasitophorous vacuoles in parasitic protozoa. The Coccidia (Sporozoa, Apicomplexa)]T V Beier
Institute of Cytology RAS, 194064, St Petersburg
Tsitologiia 45:339-56. 2003..For Toxoplasma gondii and other cyst-forming coccidia (Isospora, Sarcocystis), a definite correlation has been noticed between the extent of rhoptry and dense granule secrets released by a ..
Prevalence of endoparasites in household cat (Felis catus) populations from Transylvania (Romania) and association with risk factorsViorica Mircean
University of Agricultural Science and Veterinary Medicine, Parasitology and Parasitic Diseases Department, 3 5 Mănăştur Street, Cod 400372, Cluj Napoca, Romania
Vet Parasitol 171:163-6. 2010..3.4%), Capillaria aerophila (3.1%), Taenia taeniaeformis (2.7%), T. gondii/H. hammondi (1.2%), Sarcocystis spp. (1%), Giardia duodenalis (0.7%) and Dypillidium caninum (0.2%)...
Prevalence of dog intestinal parasites and risk perception of zoonotic infection by dog owners in São Paulo State, BrazilS Katagiri
Faculdade de Medicina Veterinaria e Zootecnia, Departamento de Parasitologia, Instituto de Biociencias, Universidade Estadual Paulista UNESP, Botucatu, SP, Brazil
Zoonoses Public Health 55:406-13. 2008..7%), Trichuris vulpis (7.1%), Dipylidium caninum (2.4%), Isospora (3.5%), Cryptosporidium (3.1%) and Sarcocystis (2.7%). Stray dogs were found more likely to be poliparasitized (P<0...
The abattoir condemnation of meat because of parasitic infection, and its economic importance: results of a retrospective study in north-eastern IranH Borji
Department of Pathobiology, School of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, 9177948974, Iran
Ann Trop Med Parasitol 104:641-7. 2010..granulosus. Sarcocystis cysts and/or Taenia cysticerci were found in ovine muscle while only Taenia cysticerci were detected in bovine ..
Identification of Tritrichomonas foetus and Giardia spp. infection in pedigree show cats in New ZealandD D Kingsbury
Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Private Bag 11222, Palmerston North 4442, New Zealand
N Z Vet J 58:6-10. 2010..To establish the presence of Tritrichomonas foetus, to investigate the prevalence of co-infection with Giardia spp., and determine risk factors for T. foetus infection in pedigree show cats in New Zealand...
[Intestinal parasites in dogs and cats with gastrointestinal symptoms in Santiago, Chile]Javier Lopez
Clínica Veterinaria Alcántara, La Florida, Santiago, Chile
Rev Med Chil 134:193-200. 2006..There is an increasing importance of pet-transmitted infections, some of those are considered emerging infections...
Research Grants
- MECHANISM-BASED DRUG SELECTION AND DESIGN: NUCLEOTIDE SABuddy Ullman; Fiscal Year: 2003..and purine salvage pathways in Toxoplasma gondii and related apicomplexan parasites, including Cryptosporidium, Sarcocystis, and Plasmodium...
- Parasite/Host Interactions and the Neurobiology of FearRobert Sapolsky; Fiscal Year: 2006..Controls will be mocked infected or infected with Sarcocystis neurona, a related protozoa that does not reproduce in a carnivore...
- HOST FACTORS MEDIATE INVASION BY CAMPYLOBACTER JEJUNILINDA MANSFIELD; Fiscal Year: 2002..jejuni invasion is facilitated due to a direct effect of some secreted/excreted product of the worms, and 4) Determine what host cell genes are differentially expressed during C. jejuni invasion. ..
- Murine models to test parasite products as cures for Inflammatory Bowel DiseaseLINDA MANSFIELD; Fiscal Year: 2007..she focused on finding naturally occurring animal models for Campylobacter jejuni and Cyst forming coccidia (Sarcocystis neurona, etc.) with the long-term goal to convert these to mouse models...
