sarcocystis

Summary

Summary: A genus of protozoa found in reptiles, birds, and mammals, including humans. This heteroxenous parasite produces muscle cysts in intermediate hosts such as domestic herbivores (cattle, sheep, pigs) and rodents. Final hosts are predators such as dogs, cats, and man.

Top Publications

  1. ncbi Epidemiology of Sarcocystis neurona infections in domestic cats (Felis domesticus) and its association with equine protozoal myeloencephalitis (EPM) case farms and feral cats from a mobile spay and neuter clinic
    J F Stanek
    Department of Veterinary Preventive Medicine, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210 1092, USA
    Vet Parasitol 117:239-49. 2003
  2. pmc Self-mating in the definitive host potentiates clonal outbreaks of the apicomplexan parasites Sarcocystis neurona and Toxoplasma gondii
    Jered M Wendte
    Molecular Parasitology Unit, Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Genet 6:e1001261. 2010
  3. ncbi Depletion of natural killer cells does not result in neurologic disease due to Sarcocystis neurona in mice with severe combined immunodeficiency
    Debra C Sellon
    Department of Veterinary Clinical Sciences, Washington State University, Pullman, Washington 99164, USA
    J Parasitol 90:782-8. 2004
  4. ncbi Humoral immunity is not critical for protection against experimental infection with Sarcocystis neurona in B-cell-deficient mice
    Sharon G Witonsky
    Department of Large Animal Clinical Sciences, Virginia Polytechnic Institute and State University Virginia Tech, Blacksburg, Virginia 24061, USA
    J Parasitol 91:830-7. 2005
  5. ncbi Structure of Sarcocystis neurona sarcocysts
    J P Dubey
    Parasite Biology, Epidemiology and Systematics Laboratory, Animal and Natural Resources Institute, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland 20705-2350, USA
    J Parasitol 87:1323-7. 2001
  6. doi Detection of antibodies against Sarcocystis neurona, Neospora spp., and Toxoplasma gondii in horses from Costa Rica
    S Dangoudoubiyam
    Department of Veterinary Science, Maxwell H Gluck Equine Research Center, University of Kentucky, Lexington, Kentucky 40546 0099, USA
    J Parasitol 97:522-4. 2011
  7. doi High prevalence of Sarcocystis calchasi sporocysts in European Accipiter hawks
    Philipp Olias
    Department of Veterinary Pathology, Freie Universitat Berlin, Robert von Ostertag Strasse 15, 14163 Berlin, Germany
    Vet Parasitol 175:230-6. 2011
  8. ncbi Prevention of meningo/encephalomyelitis due to Sarcocystis neurona infection in mice is mediated by CD8 cells
    Sharon G Witonsky
    Department of Large Animal Clinical Sciences, Virginia Maryland Regional College of Veterinary Medicine, Phase II, Duck Pond Dr, VMRCVM, Blacksburg, VA 24061 0442, USA
    Int J Parasitol 35:113-23. 2005
  9. doi Life cycle of Sarcocystis camelicanis infecting the camel (Camelus dromedarius) and the dog (Canis familiaris), light and electron microscopic study
    Fathy Abdel-Ghaffar
    Zoology Department, Faculty of Science, Cairo University, Cairo, Egypt
    Parasitol Res 106:189-95. 2009
  10. ncbi Sarcocystis neurona (Protozoa: Apicomplexa): description of oocysts, sporocysts, sporozoites, excystation, and early development
    David S Lindsay
    Department of Biomedical Sciences and Pathobiology, Virginia Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, 24061 0342, USA
    J Parasitol 90:461-5. 2004

Detail Information

Publications219 found, 100 shown here

  1. ncbi Epidemiology of Sarcocystis neurona infections in domestic cats (Felis domesticus) and its association with equine protozoal myeloencephalitis (EPM) case farms and feral cats from a mobile spay and neuter clinic
    J F Stanek
    Department of Veterinary Preventive Medicine, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210 1092, USA
    Vet Parasitol 117:239-49. 2003
    Equine protozoal myeloencephalitis (EPM) is a serious neurologic disease in the horse most commonly caused by Sarcocystis neurona. The domestic cat (Felis domesticus) is an intermediate host for S. neurona...
  2. pmc Self-mating in the definitive host potentiates clonal outbreaks of the apicomplexan parasites Sarcocystis neurona and Toxoplasma gondii
    Jered M Wendte
    Molecular Parasitology Unit, Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Genet 6:e1001261. 2010
    Tissue-encysting coccidia, including Toxoplasma gondii and Sarcocystis neurona, are heterogamous parasites with sexual and asexual life stages in definitive and intermediate hosts, respectively. During its sexual life stage, T...
  3. ncbi Depletion of natural killer cells does not result in neurologic disease due to Sarcocystis neurona in mice with severe combined immunodeficiency
    Debra C Sellon
    Department of Veterinary Clinical Sciences, Washington State University, Pullman, Washington 99164, USA
    J Parasitol 90:782-8. 2004
    b>Sarcocystis neurona is an apicomplexan parasite that is the primary etiologic agent of equine protozoal myeloencephalitis in horses...
  4. ncbi Humoral immunity is not critical for protection against experimental infection with Sarcocystis neurona in B-cell-deficient mice
    Sharon G Witonsky
    Department of Large Animal Clinical Sciences, Virginia Polytechnic Institute and State University Virginia Tech, Blacksburg, Virginia 24061, USA
    J Parasitol 91:830-7. 2005
    Immunodeficient B-cell-deficient mice (mmuMT) were infected with Sarcocystis neurona merozoites to determine the role of B cells and the humoral immune response in protective immunity...
  5. ncbi Structure of Sarcocystis neurona sarcocysts
    J P Dubey
    Parasite Biology, Epidemiology and Systematics Laboratory, Animal and Natural Resources Institute, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland 20705-2350, USA
    J Parasitol 87:1323-7. 2001
    The ultrastructure of Sarcocystis neurona sarcocysts was studied from muscle of an experimentally infected cat. The cat was killed 144 days after being fed sporocysts from a naturally infected opossum...
  6. doi Detection of antibodies against Sarcocystis neurona, Neospora spp., and Toxoplasma gondii in horses from Costa Rica
    S Dangoudoubiyam
    Department of Veterinary Science, Maxwell H Gluck Equine Research Center, University of Kentucky, Lexington, Kentucky 40546 0099, USA
    J Parasitol 97:522-4. 2011
    ..samples from 315 horses from Costa Rica, Central America, were examined for the presence of antibodies against Sarcocystis neurona, Neospora spp...
  7. doi High prevalence of Sarcocystis calchasi sporocysts in European Accipiter hawks
    Philipp Olias
    Department of Veterinary Pathology, Freie Universitat Berlin, Robert von Ostertag Strasse 15, 14163 Berlin, Germany
    Vet Parasitol 175:230-6. 2011
    The emerging Sarcocystis calchasi induces a severe and lethal central nervous disease in its intermediate host, the domestic pigeon (Columba livia f. domestica). Experimental studies have identified the Northern goshawk (Accipiter g...
  8. ncbi Prevention of meningo/encephalomyelitis due to Sarcocystis neurona infection in mice is mediated by CD8 cells
    Sharon G Witonsky
    Department of Large Animal Clinical Sciences, Virginia Maryland Regional College of Veterinary Medicine, Phase II, Duck Pond Dr, VMRCVM, Blacksburg, VA 24061 0442, USA
    Int J Parasitol 35:113-23. 2005
    Immunodeficient CD8 knockout mice were infected with Sarcocystis neurona merozoites, in order to determine the role of CD8 cells in protective immunity...
  9. doi Life cycle of Sarcocystis camelicanis infecting the camel (Camelus dromedarius) and the dog (Canis familiaris), light and electron microscopic study
    Fathy Abdel-Ghaffar
    Zoology Department, Faculty of Science, Cairo University, Cairo, Egypt
    Parasitol Res 106:189-95. 2009
    In the present study, the heteroxeneous life cycle of Sarcocystis sp. infecting camels were studied. A total of 180 slaughtered camels collected from different localities in Egypt were investigated for sarcocysts...
  10. ncbi Sarcocystis neurona (Protozoa: Apicomplexa): description of oocysts, sporocysts, sporozoites, excystation, and early development
    David S Lindsay
    Department of Biomedical Sciences and Pathobiology, Virginia Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, 24061 0342, USA
    J Parasitol 90:461-5. 2004
    ..Horses are considered accidental intermediate hosts. The structure of sporocysts of the causative agent, Sarcocystis neurona, has never been described. Sporocysts of S...
  11. pmc Sarcocystis and its complications in camels (Camelus dromedarius) of eastern provinces of Iran
    Akbar Valinezhad
    Razi Serum and Vaccine Research Institute, Mashhad, Khorasan Razavi, Eastern Iran
    Korean J Parasitol 46:229-34. 2008
    The prevalence of Sarcocystis spp. was investigated by gross and histopathological examinations in 250 camels (Camelus dromedarius) slaughtered from 2002 to 2005 in the Mashhad Slaughterhouse, eastern Iran...
  12. ncbi Clinical Sarcocystis neurona, Sarcocystis canis, Toxoplasma gondii, and Neospora caninum infections in dogs
    J P Dubey
    United States Department of Agriculture, Agricultural Research Service, Animal and Natural Resources Institute, Animal Parasitic Diseases Laboratory, Beltsville Agricultural Research Center, Beltsville, MD 20705 2350, USA
    Vet Parasitol 137:36-49. 2006
    b>Sarcocystis neurona, Sarcocystis canis, Toxoplasma gondii, and Neospora caninum are related apicomplexans that can cause systemic illness in many species of animals, including dogs...
  13. ncbi Sarcocystis inghami n. sp. (Sporozoa: Sarcocystidae) from the skeletal muscles of the Virginia opossum Didelphis virginiana in Michigan
    Hany M Elsheikha
    Molecular Epidemiology Laboratory, College of Veterinary Medicine, Michigan State University, MI 48824, USA
    Syst Parasitol 56:77-84. 2003
    This report describes the newly identified Sarcocystis inghami n. sp...
  14. pmc Sarcocystis species lethal for domestic pigeons
    Philipp Olias
    Freie Universitat Berlin, Berlin, Germany
    Emerg Infect Dis 16:497-9. 2010
    A large number of Sarcocystis spp. infect birds as intermediate hosts, but pigeons are rarely affected. We identified a novel Sarcocystis sp. that causes lethal neurologic disease in domestic pigeons in Germany...
  15. doi Intramuscular inoculation of cattle with Sarcocystis antigen results in focal eosinophilic myositis
    L Vangeel
    Laboratory of Veterinary Pathology, Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Vet Parasitol 183:224-30. 2012
    ..The etiology and pathogenesis are unclear, although it has been suggested, that Sarcocystis species are involved...
  16. doi Sarcocystis calchasi-associated neurologic disease in a domestic pigeon in North America
    A Wunschmann
    Department of Veterinary Population Medicine, Veterinary Diagnostic Laboratory, College of Veterinary Medicine, University of Minnesota, St Paul, USA
    Transbound Emerg Dis 58:526-30. 2011
    ..The cysts had a smooth wall without projections. Size and wall morphology were compatible with Sarcocystis calchasi. Polymerase chain reaction using S...
  17. ncbi Unusual biphasic disease in domestic pigeons (Columba livia f. domestica) following experimental infection with Sarcocystis calchasi
    P Olias
    Department of Veterinary Pathology, Freie Universitat Berlin, Robert von Ostertag Strasse 15, 14163 Berlin, Germany
    Avian Dis 54:1032-7. 2010
    A novel Sarcocystis species has recently been reported in the domestic pigeon (Columba livia f. domestica) as intermediate host, causing severe central nervous signs similar to Paramyxovirus-1 or Salmonella Typhimurium var. cop...
  18. ncbi Expression, purification, and biochemical characterization of a recombinant lectin of Sarcocystis muris (Apicomplexa) cyst merozoites
    H Klein
    Paul Ehrlich Institut, Federal Agency for Sera and Vaccines, FG Parasitologie Diagnostika, Langen, Germany
    Glycoconj J 15:147-53. 1998
    The mature major microneme protein of Sarcocystis muris cyst merozoites, which is known as a dimeric lectin with high affinity to galactose and some of its derivatives, was expressed in Escherichia colias a histidine-tagged fusion ..
  19. ncbi Immunohistochemical localisation of 3beta-hydroxysteroid dehydrogenase in Sarcocystis spp
    Murat Yarim
    Department of Pathology, Faculty of Veterinary Medicine, University of Kirikkale, Yahsihan, Turkey
    Parasitol Res 93:457-60. 2004
    ..In the present study, 3beta-HSD was detected in the bradyzoites enclosed in sarcocysts of Sarcocystis spp. with immunohistochemistry...
  20. doi Corvid birds (Corvidae) act as definitive hosts for Sarcocystis ovalis in moose (Alces alces)
    Bjørn Gjerde
    Department of Food Safety and Infection Biology, Section of Microbiology, Immunology and Parasitology, Norwegian School of Veterinary Science, P O Box 8146 Dep, 0033, Oslo, Norway
    Parasitol Res 107:1445-53. 2010
    Epidemiological data and a unique phylogenetic position had suggested that Sarcocystis ovalis in moose and red deer might use a definitive host other than canids, felids, or humans...
  21. pmc Sarcocystis neurona merozoites express a family of immunogenic surface antigens that are orthologues of the Toxoplasma gondii surface antigens (SAGs) and SAG-related sequences
    Daniel K Howe
    Department of Veterinary Science, 108 Gluck Equine Research Center, University of Kentucky, Lexington, KY 40546 0099, USA
    Infect Immun 73:1023-33. 2005
    b>Sarcocystis neurona is a member of the Apicomplexa that causes myelitis and encephalitis in horses but normally cycles between the opossum and small mammals. Analysis of an S...
  22. ncbi Seroprevalence of Neospora, Toxoplasma gondii and Sarcocystis neurona antibodies in horses from Jeju island, South Korea
    G D Gupta
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Connaway Hall, 1600 East Rollins Dr, Columbia, MO 65211, USA
    Vet Parasitol 106:193-201. 2002
    ..gondii equid (pony) were used. In addition, all samples were tested for antibodies to Sarcocystis neurona by immunoblot analysis. A total of 191 serum samples from clinically normal horses were evaluated...
  23. pmc Experimental induction of the two-host life cycle of Sarcocystis cruzi between dogs and Korean native calves
    S H Wee
    National Veterinary Research and Quarantine Service, MAF, Anyang 430 824
    Korean J Parasitol 39:227-32. 2001
    Eight dogs were experimentally infected with Sarcocystis by oral inoculation of cardiac muscle from naturally infected cattle...
  24. ncbi Protozoal meningoencephalitis in sea otters (Enhydra lutris): a histopathological and immunohistochemical study of naturally occurring cases
    N J Thomas
    Department of the Interior, US Geological Survey, National Wildlife Health Center, Madison, WI, USA
    J Comp Pathol 137:102-21. 2007
    ..the actively multiplicative life stages of the organisms (tachyzoites for Toxoplasma gondii and merozoites for Sarcocystis neurona) and immunohistochemical labelling were used to identify infection with S. neurona (n=22, 56.4%), T...
  25. pmc Sarcocystis spp. in human infections
    Ronald Fayer
    U S Department of Agriculture, Agricultural Research Service, Animal and Natural Resources Institute, Environmental Microbial Safety Laboratory, Beltsville, MD 20705, USA
    Clin Microbiol Rev 17:894-902, table of contents. 2004
    b>Sarcocystis species are intracellular protozoan parasites with an intermediate-definitive host life cycle based on a prey-predator relationship...
  26. ncbi Clinical Sarcocystis neurona encephalomyelitis in a domestic cat following routine surgery
    J P Dubey
    Parasite Biology, Epidemiology and Systematics Laboratory, Agricultural Research Service, US Department of Agriculture, Animal and Natural Resources Institute, Beltsville Agricultural Research Center, MD 20705 2350, USA
    Vet Parasitol 112:261-7. 2003
    b>Sarcocystis neurona is an important cause of equine protozoal myeloencephalitis (EPM) in horses in the Americas...
  27. ncbi Characterization of a serine protease activity in Sarcocystis neurona merozoites
    S C Barr
    Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA
    J Parasitol 89:385-8. 2003
    b>Sarcocystis neurona merozoites were examined for their ability to invade and divide in bovine turbinate (BT) cell cultures after treatment with cysteine (iodoacetamide), aspartic (pepstatin A), metallo-(1,10-phenanthroline and ethylene ..
  28. ncbi Prevalence of Neospora hughesi and Sarcocystis neurona antibodies in horses from various geographical locations
    D Vardeleon
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia 65211, USA
    Vet Parasitol 95:273-82. 2001
    ..In addition, all samples were tested for antibodies to Sarcocystis neurona by immunoblot analysis. A total of 208 samples was evaluated...
  29. ncbi Prevalence of antibodies to Neospora caninum, Sarcocystis neurona, and Toxoplasma gondii in wild horses from central Wyoming
    J P Dubey
    Animal Parasitic Diseases Laboratory, Animal and Natural Resources Institute, Agricultural Research Service, United States Department of Agriculture, Building 1001, Beltsville, Maryland 20705 2350, USA
    J Parasitol 89:716-20. 2003
    b>Sarcocystis neurona, Neospora caninum, N. hughesi, and Toxoplasma gondii are 4 related coccidians considered to be associated with encephalomyelitis in horses. The source of infection for N...
  30. ncbi Surveillance of endoparasitic infections and the first report of Physaloptera sp. and Sarcocystis spp. in farm rodents and shrews in central Taiwan
    Kwong Chung Tung
    Department of Veterinary Medicine, College of Veterinary Medicine, National Chung Hsing University, 250 Kuo Kuuang Road, Taichung, Taiwan
    J Vet Med Sci 71:43-7. 2009
    ..1%), Syphacia muris (2.1%), Trichosomoides crassicauda (29.5%), and Trichurus sp. (1.1%), and one protozoan, Sarcocystis spp. (33.7%). Physaloptera sp. from S. murinus and Sarcocystis spp. from both R. norvegicus and R...
  31. ncbi Prevalence of antibodies to Sarcocystis neurona, Toxoplasma gondii and Neospora caninum in horses from Argentina
    J P Dubey
    Parasite Biology and Epidemiology Laboratory, United States Department of Agriculture, Agricultural Research Service, Livestock and Poultry Sciences Institute, Beltsville, MD 20705 2350, USA
    Vet Parasitol 86:59-62. 1999
    Sera from 76 horses from Argentina were examined for antibodies to Sarcocystis neurona, Toxoplasma gondii and Neospora caninum. Antibodies to S. neurona were found in 27 (35...
  32. pmc Prey choice and habitat use drive sea otter pathogen exposure in a resource-limited coastal system
    Christine K Johnson
    Wildlife Health Center, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Proc Natl Acad Sci U S A 106:2242-7. 2009
    ..sea otters and evaluated infection with 2 disease-causing protozoal pathogens, Toxoplasma gondii and Sarcocystis neurona, to reveal risks that increased the likelihood of pathogen exposure...
  33. doi Horses experimentally infected with Sarcocystis neurona develop altered immune responses in vitro
    Sharon G Witonsky
    Department of Large Animal Clinical Sciences, Phase II, Duck Pond Dr, Virginia Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, Virginia 24061 0442, USA
    J Parasitol 94:1047-54. 2008
    Equine protozoal myeloencephalitis (EPM) due to Sarcocystis neurona infection is 1 of the most common neurologic diseases in horses in the United States...
  34. doi Sarcocystis neurona: molecular characterization of enolase domain I region and a comparison to other protozoa
    K E Bolten
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon Tharp Street, Columbus, OH 43210, USA
    Exp Parasitol 120:108-12. 2008
    b>Sarcocystis neurona causes protozoal myeloencephalitis and has the ability to infect a wide host range in contrast to other Sarcocystis species. In the current study, five S...
  35. doi Characterization of Sarcocystis from four species of hawks from Georgia, USA
    Michael J Yabsley
    Daniel B Warnell School of Forestry and Natural Resources, University of Georgia, Athens, Georgia 30602, USA
    J Parasitol 95:256-9. 2009
    During 2001 to 2004, 4 species of hawks (Buteo and Accipiter spp.) from Georgia were surveyed for Sarcocystis spp. infections by examining intestinal sections. In total, 159 of 238 (66...
  36. ncbi Sarcocystis lindsayi n. sp. (Protozoa: Sarcocystidae) from the South American opossum, Didelphis albiventris from Brazil
    J P Dubey
    United States Department of Agriculture, Agricultural Research Service, Animal and Natural Resources Institute, Parasite Biology, Epidemiology and Systematics Laboratory, Beltsville, Maryland 20705 2350, USA
    J Eukaryot Microbiol 48:595-603. 2001
    A new species, Sarcocystis lindsayi n. sp., is proposed for a parasite resembling Sarcocystis falcatula...
  37. ncbi New comprehension of the apicoplast of Sarcocystis by transmission electron tomography
    Cveta Tomova
    Institut für Zoologie Spezielle Zoologie, Technische Universitat Dresden, Helmholtzstrasse 10, D 01062 Dresden, Germany
    Biol Cell 98:535-45. 2006
    BACKGROUND INFORMATION: Apicomplexan parasites (like Plasmodium, Toxoplasma, Eimeria and Sarcocystis) contain a distinctive organelle, the apicoplast, acquired by a secondary endosymbiotic process analogous to chloroplasts and ..
  38. ncbi Eosinophilic myositis due to Sarcocystis hominis in a beef cow
    W Wouda
    Animal Health Service Ltd, Post Box 9, 7400 AA Deventer, The Netherlands
    J Comp Pathol 135:249-53. 2006
    ..By transmission electron microscopy the sarcocysts were identified as Sarcocystis hominis, based on the morphology of villar protrusions of the sarcocyst wall, which were broad-based and ..
  39. ncbi A genetically diverse but distinct North American population of Sarcocystis neurona includes an overrepresented clone described by 12 microsatellite alleles
    Ingrid M Asmundsson
    Animal Parasitic Disease Laboratory, Animal and Natural Resources Institute, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, USA
    Infect Genet Evol 6:352-60. 2006
    ..true for tissue-cyst forming coccidia, and to address evolutionary and taxonomic problems within the genus Sarcocystis, we characterized polymorphic microsatellite markers in Sarcocystis neurona, the major causative agent of ..
  40. pmc Genetic variation among isolates of Sarcocystis neurona, the agent of protozoal myeloencephalitis, as revealed by amplified fragment length polymorphism markers
    H M Elsheikha
    Department of Large Animal Clinical Sciences, Michigan State University, East Lansing, MI 48824, USA
    Infect Immun 74:3448-54. 2006
    b>Sarcocystis neurona causes serious neurological disease in horses and other vertebrates in the Americas. Based on epidemiological data, this parasite has recently emerged...
  41. ncbi Plastid segregation and cell division in the apicomplexan parasite Sarcocystis neurona
    Shipra Vaishnava
    Department of Cellular Biology, University of Georgia, Athens, GA 30602, USA
    J Cell Sci 118:3397-407. 2005
    ..We have studied the replication and segregation of this important organelle using the parasite Sarcocystis neurona as a cell biological model...
  42. ncbi Experimental inoculation of domestic cats (Felis domesticus) with Sarcocystis neurona or S. neurona-like merozoites
    M Butcher
    College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    Vet Parasitol 107:1-14. 2002
    b>Sarcocystis neurona is the parasite most commonly associated with equine protozoal myeloencephalitis (EPM). Recently, cats (Felis domesticus) have been demonstrated to be an experimental intermediate host in the life cycle of S. neurona...
  43. ncbi Mapping of quantitative trait loci affecting resistance/susceptibility to Sarcocystis miescheriana in swine
    Gerald Reiner
    Department of Veterinary Clinical Sciences, University of Giessen, D 35392 Giessen, Germany
    Genomics 89:638-46. 2007
    ..In swine, e.g., marked differences in resistance/susceptibility to Sarcocystis miescheriana have been shown between Chinese Meishan and European Pietrain pigs, and these differences are ..
  44. doi A protozoal-associated epizootic impacting marine wildlife: mass-mortality of southern sea otters (Enhydra lutris nereis) due to Sarcocystis neurona infection
    Melissa A Miller
    Marine Wildlife Veterinary Care and Research Center, Santa Cruz, CA 95060, USA
    Vet Parasitol 172:183-94. 2010
    ..lesions consistent with an infectious etiology, and further investigation confirmed the protozoan parasite Sarcocystis neurona as the underlying cause. Tissues from 94% of examined otters were PCR-positive for S...
  45. pmc Limited genetic diversity among Sarcocystis neurona strains infecting southern sea otters precludes distinction between marine and terrestrial isolates
    J M Wendte
    Molecular Parasitology Unit, Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 0425, USA
    Vet Parasitol 169:37-44. 2010
    b>Sarcocystis neurona is an apicomplexan parasite identified as a cause of fatal neurological disease in the threatened southern sea otter (Enhydra lutris nereis). In an effort to characterize virulent S...
  46. pmc Ultrastructural and molecular confirmation of the development of Sarcocystis neurona tissue cysts in the central nervous system of southern sea otters (Enhydra lutris nereis)
    M A Miller
    Marine Wildlife Veterinary Care and Research Center, California Department of Fish and Game, 1451 Shaffer Road, Santa Cruz, CA 95060, USA
    Int J Parasitol 39:1363-72. 2009
    In 2004, three wild sea otters were diagnosed with putative Sarcocystis neurona-associated meningoencephalitis by histopathology and immunohistochemistry...
  47. doi Modest genetic differentiation among North American populations of Sarcocystis neurona may reflect expansion in its geographic range
    N Sundar
    United States Department of Agriculture, Agricultural Research Service, Animal Natural Resources Institute, Animal Parasitic Diseases Laboratory, Beltsville, MD 20705 2350, USA
    Vet Parasitol 152:8-15. 2008
    b>Sarcocystis neurona is an important cause of neurological disease in horses (equine protozoal myeloencephalitis, EPM) and sea otters in the United States...
  48. doi Molecular characterization of Sarcocystis neurona strains from opossums (Didelphis virginiana) and intermediate hosts from Central California
    Daniel Rejmanek
    Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA
    Vet Parasitol 170:20-9. 2010
    b>Sarcocystis neurona is a significant cause of neurological disease in horses and other animals, including the threatened Southern sea otter (Enhydra lutris nereis). Opossums (Didelphis virginiana), the only known definitive hosts for S...
  49. ncbi Reduction of transmission stages concomitant with increased host immune responses to hypervirulent Sarcocystis singaporensis, and natural selection for intermediate virulence
    T Jakel
    Division of Parasitology, Department of Zoology, University of Hohenheim, Emil Wolff Strasse 34, 70599 Stuttgart, Germany
    Int J Parasitol 31:1639-47. 2001
    ..depending on inoculum size) and host immune reactions were examined for the apicomplexan protozoan Sarcocystis singaporensis...
  50. ncbi A review of Sarcocystis neurona and equine protozoal myeloencephalitis (EPM)
    J P Dubey
    United States Department of Agriculture, Agricultural Research Service, Animal and Natural Resources Institute, Beltsville Agricultural Research Center, MD 20705 2350, USA
    Vet Parasitol 95:89-131. 2001
    ..The protozoan most commonly associated with EPM is Sarcocystis neurona. The complete life cycle of S...
  51. ncbi Analysis of the Sarcocystis neurona microneme protein SnMIC10: protein characteristics and expression during intracellular development
    Jessica S Hoane
    Department of Veterinary Science, University of Kentucky, 108 Gluck Equine Research Center, Lexington, KY 40546 0099, USA
    Int J Parasitol 33:671-9. 2003
    b>Sarcocystis neurona, an apicomplexan parasite, is the primary causative agent of equine protozoal myeloencephalitis. Like other members of the Apicomplexa, S...
  52. doi A novel Sarcocystis-associated encephalitis and myositis in racing pigeons
    P Olias
    Department of Veterinary Pathology, Freie Universitat Berlin, Robert von Ostertag Strasse 15, Berlin, Germany
    Avian Pathol 38:121-8. 2009
    ..domestica) have previously been attributed to infection with Sarcocystis falcatula, which is shed in the faeces of the opossum (Didelphis virginiana)...
  53. doi Brown-headed cowbirds (Molothrus ater) harbor Sarcocystis neurona and act as intermediate hosts
    L S Mansfield
    Departments of Large Animal Clinical Sciences and Microbiology and Molecular Genetics, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA
    Vet Parasitol 153:24-43. 2008
    We tested the hypothesis that brown-headed cowbirds (Molothrus ater) harbor Sarcocystis neurona, the agent of equine protozoal myeloencephalitis (EPM), and act as intermediate hosts for this parasite...
  54. ncbi Toxoplasma gondii, Neospora caninum, Sarcocystis neurona, and Sarcocystis canis-like infections in marine mammals
    J P Dubey
    United States Department of Agriculture, Agricultural Research Service, Animal and Natural Resources Institute, Animal Parasitic Diseases Laboratory, Beltsville, MD 20705 2350, USA
    Vet Parasitol 116:275-96. 2003
    Toxoplasma gondii, Neospora caninum, Sarcocystis neurona, and S. canis are related protozoans that can cause mortality in many species of domestic and wild animals. Recently, T. gondii and S...
  55. doi In vitro efficacy of nitro- and halogeno-thiazolide/thiadiazolide derivatives against Sarcocystis neurona
    G Gargala
    Parasitology Department, University of Rouen, France
    Vet Parasitol 162:230-5. 2009
    b>Sarcocystis neurona is an obligate intracellular parasite that causes equine protozoal myeloencephalitis (EPM)...
  56. ncbi Assessment of Sarcocystis neurona sporocyst viability and differentiation between viable and nonviable sporocysts using propidium iodide stain
    Hany M Elsheikha
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan 48824, USA
    J Parasitol 90:872-5. 2004
    b>Sarcocystis neurona has become recognized as the major causative agent of equine protozoal myeloencephalitis (EPM) in the Americas. At least 3 pathogenic species of Sarcocystis, including S. neurona, can be isolated from opossums...
  57. ncbi Prevalence of agglutinating antibodies to Sarcocystis neurona in raccoons (Procyon lotor) from an urban area of Virginia
    Katie Hancock
    Center for Molecular Medicine and Infectious Diseases, Department of Biomedical Sciences and Pathobiology, Virginia Maryland Regional College of Veterinary Medicine, Virginia Tech, 1410 Prices Fork Road, Blacksburg, Virginia 24061 0342, USA
    J Parasitol 90:881-2. 2004
    ..myeloencephalitis is the most important protozoan disease of horses in North America and is usually caused by Sarcocystis neurona. Natural and experimentally induced cases of encephalitis caused by S...
  58. ncbi Cell-mediated immune responses in horses with equine protozoal myeloencephalitis
    Jennifer A Spencer
    Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, Alabama 36849, USA
    J Parasitol 90:428-30. 2004
    ..myeloencephalitis (EPM) is a neurologic syndrome seen in horses from the Americas and is mainly caused by Sarcocystis neurona...
  59. ncbi Evaluation and comparison of an indirect fluorescent antibody test for detection of antibodies to Sarcocystis neurona, using serum and cerebrospinal fluid of naturally and experimentally infected, and vaccinated horses
    Paulo C Duarte
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, One Shields Avenue, Davis, California 95616, USA
    J Parasitol 90:379-86. 2004
    ..test (IFAT) using serum and cerebrospinal fluid (CSF) of horses naturally and experimentally infected with Sarcocystis neurona, to assess the correlation between serum and CSF titers, and to determine the effect of S...
  60. ncbi Evaluation of immune responses in horses immunized using a killed Sarcocystis neurona vaccine
    Antoinette E Marsh
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    Vet Ther 5:34-42. 2004
    Clinically normal horses developed cellular immunity to Sarcocystis neurona following IM vaccination with a commercial killed S. neurona vaccine, as indicated by the development of measurable anti-S...
  61. ncbi Protective immune response to experimental infection with Sarcocystis neurona in 57BL/6 mice
    Sharon G Witonsky
    Department of Large Animal Clinical Sciences, Virginia Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University Virginia Tech Blacksburg, Virginia 24061 0442, USA
    J Parasitol 89:924-31. 2003
    Immunocompetent C57BL/6 mice were infected with Sarcocystis neurona merozoites to assess the protective immune response to active infection. Using a direct agglutination test, all infected mice seroconverted to S...
  62. pmc Infection of immunodeficient horses with Sarcocystis neurona does not result in neurologic disease
    Debra C Sellon
    Department of Veterinary Clinical Sciences, Washington State University, Pullman, WA 99163, USA
    Clin Diagn Lab Immunol 11:1134-9. 2004
    ..is a progressive neurologic disease of horses most commonly caused by infection with the apicomplexan parasite Sarcocystis neurona. Factors affecting neuroinvasion and neurovirulence have not been determined...
  63. ncbi Antigenic evaluation of a recombinant baculovirus-expressed Sarcocystis neurona SAG1 antigen
    G D Gupta
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia, Missouri 65211, USA
    J Parasitol 90:1027-33. 2004
    b>Sarcocystis neurona is the primary parasite associated with equine protozoal myeloencephalitis (EPM). This is a commonly diagnosed neurological disorder in the Americas that infects the central nervous system of horses...
  64. ncbi Diagnosis of Sarcocystis cruzi, Neospora caninum, and Toxoplasma gondii infections in cattle
    G More
    Laboratorio de Inmunoparasitologia, Cátedra de Parasitología y Enfermedades Parasitarias, Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, 60 y 118, 1900 La Plata, Argentina
    Parasitol Res 102:671-5. 2008
    The aim of the study was to diagnose Sarcocystis sp. infections in cattle and to detect coinfections by Toxoplasma gondii and/or Neospora caninum...
  65. ncbi Immune response to Sarcocystis neurona infection in naturally infected horses with equine protozoal myeloencephalitis
    Jibing Yang
    Department of Large Animal Clinical Sciences, Phase II, Duck Pond Dr, Virginia Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, 24061, USA
    Vet Parasitol 138:200-10. 2006
    ..The primary etiologic agent is Sarcocystis neurona...
  66. ncbi Increased presence of T lymphocytes in central nervous system of EPM affected horses
    Patricia Scott
    Department of Large Animal Clinical Sciences, Virginia Polytechnic Institute and State University, Blacksburg 24061 0442, USA
    J Parasitol 91:1499-502. 2005
    Equine protozoal myeloencephalitis (EPM), caused by Sarcocystis neurona infection in the central nervous system (CNS), affects up to 1% of all horses during their lifetimes...
  67. ncbi Early migration of Sarcocystis neurona in ponies fed sporocysts
    E Elitsur
    Department of Veterinary Preventive Medicine, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio 43210 1092, USA
    J Parasitol 93:1222-5. 2007
    b>Sarcocystis neurona is the most important cause of equine protozoal myeloencephalitis (EPM), a neurologic disease of the horse. In the present work, the kinetics of S. neurona invasion is determined in the equine model...
  68. ncbi Prevalence of Sarcocystis neurona and Neospora spp. infection in horses from Brazil based on presence of serum antibodies to parasite surface antigen
    Jessica S Hoane
    Department of Veterinary Science, University of Kentucky, 108 Gluck Equine Research Center, Lexington, KY 40546 0099, USA
    Vet Parasitol 136:155-9. 2006
    ..tested for antibodies against the major surface antigens SnSAG4 and NhSAG1 to determine the seroprevalence of Sarcocystis neurona and Neospora hughesi, respectively. Antibodies against SnSAG4 were detected in 669 (69...
  69. ncbi What is your neurologic diagnosis? Equine protozoal myeloencephalitis
    Laura H Javsicas
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
    J Am Vet Med Assoc 232:201-4. 2008
  70. ncbi Persistence of serum antibodies to Sarcocystis neurona in horses moved from North America to India
    Christopher M Brown
    Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Canada
    J Vet Intern Med 20:994-7. 2006
    The study reported here was undertaken to assess the presence of antibodies to Sarcocystis neurona in the serum of horses of North American origin that had been relocated for 1 year or more to India (ie, outside of the known endemic ..
  71. pmc Enzyme-linked immunosorbent assays for detection of equine antibodies specific to Sarcocystis neurona surface antigens
    Jessica S Hoane
    Department of Veterinary Science, University of Kentucky, Lexington, KY 40546 0099, USA
    Clin Diagn Lab Immunol 12:1050-6. 2005
    b>Sarcocystis neurona is the primary causative agent of equine protozoal myeloencephalitis (EPM), a common neurologic disease of horses in the Americas...
  72. ncbi Phylogenetic relationships of Sarcocystis neurona of horses and opossums to other cyst-forming coccidia deduced from SSU rRNA gene sequences
    Hany M Elsheikha
    Department of Large Animal Clinical Sciences, Michigan State University, East Lansing, MI 48824, USA
    Parasitol Res 97:345-57. 2005
    ..subunit rRNA (ssurRNA) gene were performed to examine the origin, phylogeny, and biogeographic relationships of Sarcocystis neurona isolates from opossums and horses from the State of Michigan, USA, in relation to other cyst-forming ..
  73. doi Investigation of SnSPR1, a novel and abundant surface protein of Sarcocystis neurona merozoites
    Deqing Zhang
    Department of Veterinary Sciences, University of Kentucky, Gluck Equine Research Center, Lexington, KY 40546 0099, USA
    Vet Parasitol 152:210-9. 2008
    ..sequence tag (EST) sequencing project has produced over 15,000 partial cDNA sequences from the equine pathogen Sarcocystis neurona...
  74. ncbi Evidence to support horses as natural intermediate hosts for Sarcocystis neurona
    Thomas Mullaney
    Diagnostic Center for Population and Animal Health DCPAH, College of Veterinary Medicine, Michigan State University MSU, East Lansing, MI 48824, USA
    Vet Parasitol 133:27-36. 2005
    Opossums (Didelphis spp.) are the definitive host for the protozoan parasite Sarcocystis neurona, the causative agent of equine protozoal myeloencephalitis (EPM)...
  75. ncbi Experimental infection of ponies with Sarcocystis fayeri and differentiation from Sarcocystis neurona infections in horses
    W J A Saville
    Department of Veterinary Preventive Medicine, College of Veterinary Medicine, Ohio State University, Columbus, Ohio 43210 1092, USA
    J Parasitol 90:1487-91. 2004
    b>Sarcocystis neurona and Sarcocystis fayeri infections are common in horses in the Americas...
  76. ncbi Risk of transplacental transmission of Sarcocystis neurona and Neospora hughesi in California horses
    Paulo C Duarte
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, One Shields Avenue, Davis, California 95616, USA
    J Parasitol 90:1345-51. 2004
    The study objective was to assess the risk of transplacental transmission of Sarcocystis neurona and Neospora hughesi in foals from 4 California farms during 3 foaling seasons...
  77. doi Effect of intermittent oral administration of ponazuril on experimental Sarcocystis neurona infection of horses
    Robert J MacKay
    Department of Large Animal Clinical Sciences, University of Florida, Gainesville, FL 32610, USA
    Am J Vet Res 69:396-402. 2008
    To evaluate the effect of intermittent oral administration of ponazuril on immunoconversion against Sarcocystis neurona in horses inoculated intragastrically with S neurona sporocysts.
  78. doi Antibody index and specific antibody quotient in horses after intragastric administration of Sarcocystis neurona sporocysts
    Katherine A Heskett
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
    Am J Vet Res 69:403-9. 2008
    To investigate the use of a specific antibody index (AI) that relates Sarcocystis neurona-specific IgG quotient (Q(SN)) to total IgG quotient (Q(IgG)) for the detection of the anti-S neurona antibody fraction of CNS origin in CSF samples ..
  79. ncbi Cross-sectional survey in pig breeding farms in Hesse, Germany: seroprevalence and risk factors of infections with Toxoplasma gondii, Sarcocystis spp. and Neospora caninum in sows
    I M Damriyasa
    Institute of Parasitology, Justus Liebig University Giessen, Rudolf Buchheim Strasse 2, 35392 Giessen, Germany
    Vet Parasitol 126:271-86. 2004
    ..survey was performed to estimate the prevalences of antibodies to Toxoplasma gondii (ELISA, IFAT), Sarcocystis spp. (ELISA, using S...
  80. ncbi Parasitemia in an immunocompetent horse experimentally challenged with Sarcocystis neurona sporocysts
    M G Rossano
    The Population Medicine Center, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA
    Vet Parasitol 127:3-8. 2005
    ..Most cases are attributed to infection of the central nervous system with Sarcocystis neurona...
  81. ncbi Life cycle of Sarcocystis neurona in its natural intermediate host, the raccoon, Procyon lotor
    J F Stanek
    Department of Veterinary Preventive Medicine, College of Veterinary Medicine, The Ohio State University, 1900 Coffey Road, Columbus, Ohio 43210 1092, USA
    J Parasitol 88:1151-8. 2002
    b>Sarcocystis neurona causes encephalomyelitis in many species of mammals and is the most important cause of neurologic disease in the horse...
  82. ncbi The seroprevalence of antibodies to Sarcocystis neurona in Michigan equids
    M G Rossano
    The Population Medicine Center, College of Veterinary Medicine, A-109 Veterinary Medical Center, Michigan State University, 48824-1314, East Lansing, MI, USA
    Prev Vet Med 48:113-28. 2001
    A cross-sectional study of serum antibodies to Sarcocystis neurona (the etiologic agent of equine protozoal myeloencephalitis, EPM) was performed on Michigan equids. Our objectives were to determine the seroprevalence of antibodies to S...
  83. ncbi Reactivity against Sarcocystis neurona and Neospora by serum antibodies in healthy French horses from two farms with previous equine protozoal myeloencephalitis-like cases
    P H Pitel
    Laboratoire Departemental Frank Duncombe, 1 Route de Rosel, Caen, France
    Vet Parasitol 111:1-7. 2003
    b>Sarcocystis neurona is considered a leading cause of equine protozoal myeloencephalitis (EPM), a common infectious neurological disease in horses in the Americas. EPM-like cases associated with S...
  84. ncbi Sensitivity and specificity of western blot testing of cerebrospinal fluid and serum for diagnosis of equine protozoal myeloencephalitis in horses with and without neurologic abnormalities
    Barbara M Daft
    California Animal Health and Food Safety Laboratory System, School of Veterinary Medicine, University of California, Davis, San Bernardino 92408, USA
    J Am Vet Med Assoc 221:1007-13. 2002
    ..To determine sensitivity and specificity of western blot testing (WBT) of CSF and serum for diagnosis of equine protozoal myeloencephalitis (EPM) in horses with and without neurologic abnormalities...
  85. ncbi Clinical diagnosis of equine protozoal myeloencephalitis (EPM)
    Martin Furr
    Marion duPont Scott Equine Medical Center, Virginia Maryland Regional College of Veterinary Medicine, Leesburg, VA 20177, USA
    J Vet Intern Med 16:618-21. 2002
  86. ncbi Sarcocystis neurona: parasitemia in a severe combined immunodeficient (SCID) horse fed sporocysts
    Maureen T Long
    Department of Large Animal Clinical Sciences, University of Florida, Gainesville, FL 32610, USA
    Exp Parasitol 100:150-4. 2002
    b>Sarcocystis neurona was isolated from the blood of a 5-month-old Arabian foal with severe combined immunodeficiency...
  87. ncbi Neurologic disease in gamma-interferon gene knockout mice caused by Sarcocystis neurona sporocysts collected from opossums fed armadillo muscle
    M A Cheadle
    Department of Pathobiology, College of Veterinary Medicine, University of Florida, PO Box 110880, 2015 SW 16th Avenue, Gainesville, FL 32610 0880, USA
    Vet Parasitol 103:65-9. 2002
    Fifteen gamma-interferon gene knockout mice were each orally inoculated with 5 x 10(3) Sarcocystis sporocysts derived from Virginia opossums (Didelphis virginiana) fed nine-banded armadillo (Dasypus novemcinctus) muscle containing ..
  88. ncbi Detection of antibodies against Sarcocystis neurona in cerebrospinal fluid from clinically normal neonatal foals
    Anne Grimsley Cook
    Department of Large Animal Clinical Sciences, Virginia Maryland Regional College of Veterinary Medicine, Blacksburg, VA, USA
    J Am Vet Med Assoc 220:208-11. 2002
    To determine whether antibodies against Sarcocystis neurona could be detected in CSF from clinically normal neonatal (2 to 7 days old) and young (2 to 3 months old) foals.
  89. ncbi Mice lacking the gene for inducible or endothelial nitric oxide are resistant to sporocyst induced Sarcocystis neurona infections
    Alexa C Rosypal
    Department of Biomedical Sciences and Pathobiology, Center for Molecular Medicine and Infectious Diseases, Virginia Maryland Regional College of Veterinary Medicine, 1410 Prices Fork Road, Blacksburg, VA 24061 0342, USA
    Vet Parasitol 103:315-21. 2002
    ..syndrome in horses from the Americas and is usually caused by infection with the apicomplexan parasite, Sarcocystis neurona. Little is known about the role of immunobiological mediators to this parasite...
  90. ncbi Detection of Sarcocystis neurona antibodies in French horses with neurological signs
    P H Pitel
    Int J Parasitol 32:481-5. 2002
  91. ncbi Effects of high temperature and disinfectants on the viability of Sarcocystis neurona sporocysts
    J P Dubey
    Parasite Biology, Epidemiology and Systematics Laboratory, Building 1001, Animal and Natural Resources Institute, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland 20705 2350, USA
    J Parasitol 88:1252-4. 2002
    The effect of moist heat and several disinfectants on Sarcocystis neurona sporocysts was investigated...
  92. pmc Reduced levels of nitric oxide metabolites in cerebrospinal fluid are associated with equine protozoal myeloencephalitis
    Chinedu J Njoku
    Department of Veterinary Preventive Medicine, The Ohio State University, Columbus, Ohio 43210, USA
    Clin Diagn Lab Immunol 9:605-10. 2002
    ..EPM) is a disease of horses that is primarily associated with infection with the apicomplexan Sarcocystis neurona...
  93. ncbi Effect of a single dose of ponazuril on neural infection and clinical disease in Sarcocystis neurona-challenged interferon-gamma knockout mice
    Robert P Franklin
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, 2015 SW 16th Ave, Gainesville, FL 32610, USA
    Vet Parasitol 114:123-30. 2003
    Interferon gamma-knockout mice were challenged with 5000 Sarcocystis neurona sporocysts acquired from a naturally infected opossum. Ponazuril was administered once, by gavage, at day 1, 3, 7, 10, or 14 post-infection (pi)...
  94. ncbi First case report of Sarcocystis neurona-induced equine protozoal myeloencephalitis in Japan
    Yoshinari Katayama
    Epizootic Research Station, Equine Research Institute, Japan Racing Association, Tochigi, Japan
    J Vet Med Sci 65:757-9. 2003
    ..Immunohistochemically, shizonts were occasionally observed and were positive for anti-Sarcocystis neurona (S. neurona) antiserum. S...
  95. ncbi Serologic responses of cats against experimental Sarcocystis neurona infections
    J P Dubey
    United States Department of Agriculture, Agricultural Research Service, Animal and Natural Resources Institute, Parasite Biology, Epidemiology and Systematics Laboratory, Building 1001, Beltsville, MD 20705 2350, USA
    Vet Parasitol 107:265-9. 2002
    b>Sarcocystis neurona is the most important cause of a neurologic disease of horses, equine protozoal myeloencephalitis (EPM). Cats and other carnivores can act as its intermediate hosts and horses are aberrant hosts...
  96. ncbi Assessing the agreement of Western blot test results for paired serum and cerebrospinal fluid samples from horses tested for antibodies to Sarcocystis neuronaf
    M G Rossano
    The Population Medicine Center, A 59 Veterinary Medical Center, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA
    Vet Parasitol 115:233-8. 2003
    ..EPM) is a neurological disease of equids that is caused by infection of the central nervous system with Sarcocystis neurona...
  97. ncbi Suspected protozoal myeloencephalitis in a two-month-old colt
    L C Gray
    Veterinary Medical Teaching Hospital, Large Animal Clinic, Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis 95616, USA
    Vet Rec 149:269-73. 2001
    ..imaging (MRI), peripheral nerve biopsy, and Western blot analysis for the presence of intrathecal antibodies to Sarcocystis neurona, the causative agent of equine protozoal myeloencephalitis...
  98. ncbi Comparison of a serum indirect fluorescent antibody test with two Western blot tests for the diagnosis of equine protozoal myeloencephalitis
    Paulo C Duarte
    Department of Medicine and Epidemiology, School of Veterinary Medicine, One Shields Avenue, University of California, Davis, CA 95616 8737, USA
    J Vet Diagn Invest 15:8-13. 2003
    ..2% (72.6-95.7%), and 69.2% (52.4-83%), respectively. The overall accuracy of the IFAT was shown to be better than that of the WBs and, therefore, the test has potential for use in the diagnosis of EPM caused by Sarcocystis neurona.
  99. ncbi Protozoan infections (Toxoplasma gondii, Neospora caninum and Sarcocystis spp.) in sheep and goats: recent advances
    D Buxton
    Division of Virology, Moredun Research Institute, International Research Centre, Scotland, UK
    Vet Res 29:289-310. 1998
    ..b>Sarcocystis, which exists as numerous species, undergoes a coccidian-like life cycle with each having a distinctive ..
  100. ncbi The prevalence of intestinal parasites in dogs from Prague, rural areas, and shelters of the Czech Republic
    S Dubná
    Department of Zoology and Fisheries, Faculty of Agrobiology, Food and Natural Resources, Czech University of Agriculture in Prague, Kamycka 957, 165 21 Prague 6, Suchdol, Czech Republic
    Vet Parasitol 145:120-8. 2007
    ..1.1%), Taenia-type (1.0%), Giardia spp. (0.1%), Toxascaris sp. (0.9%), Dipylidium sp. (0.7%), Sarcocystis spp. (0.6%), Capillaria spp. (0.6%), Neospora/Hammondia spp. (0.5%), Ancylostoma sp. (0.4%), Uncinaria sp. (0...
  101. doi Emerging food-borne parasites
    P Dorny
    Department of Animal Health, Institute of Tropical Medicine, B 2000 Antwerp, Belgium
    Vet Parasitol 163:196-206. 2009
    ..However, it is often not very sensitive, frequently not practised, and not done for T. gondii and Sarcocystis spp...

Research Grants16

  1. MECHANISM-BASED DRUG SELECTION AND DESIGN: NUCLEOTIDE SA
    Buddy Ullman; Fiscal Year: 2003
    ..and purine salvage pathways in Toxoplasma gondii and related apicomplexan parasites, including Cryptosporidium, Sarcocystis, and Plasmodium...
  2. Parasite/Host Interactions and the Neurobiology of Fear
    Robert Sapolsky; Fiscal Year: 2006
    ..Controls will be mocked infected or infected with Sarcocystis neurona, a related protozoa that does not reproduce in a carnivore...
  3. HOST FACTORS MEDIATE INVASION BY CAMPYLOBACTER JEJUNI
    LINDA MANSFIELD; Fiscal Year: 2002
    ..jejuni invasion is facilitated due to a direct effect of some secreted/excreted product of the worms, and 4) Determine what host cell genes are differentially expressed during C. jejuni invasion. ..
  4. Murine models to test parasite products as cures for Inflammatory Bowel Disease
    LINDA MANSFIELD; Fiscal Year: 2007
    ..she focused on finding naturally occurring animal models for Campylobacter jejuni and Cyst forming coccidia (Sarcocystis neurona, etc.) with the long-term goal to convert these to mouse models...