cryptosporidium

Summary

Summary: A genus of coccidian parasites of the family CRYPTOSPORIDIIDAE, found in the intestinal epithelium of many vertebrates including humans.

Top Publications

  1. ncbi Cryptosporidium infection in domestic geese (Anser anser f. domestica) detected by in-situ hybridization
    S Chvala
    Department of Pathobiology, Institute of Pathology and Forensic Veterinary Medicine, Veterinarplatz 1, A 1210 Vienna, Austria
    J Comp Pathol 134:211-8. 2006
  2. ncbi Molecular epidemiology of Cryptosporidium in humans and cattle in The Netherlands
    Peter R Wielinga
    National Institute for Public Health and the Environment RIVM, Centre for Infectious Disease Control CIb, Laboratory for Zoonoses and Environmental Microbiology LZO, Antonie van Leeuwenhoeklaan 9, Bilthoven, The Netherlands
    Int J Parasitol 38:809-17. 2008
  3. ncbi Molecular epidemiology of cryptosporidiosis: an update
    Lihua Xiao
    Division of Parasitic Diseases, National Center for Zoonotic, Vector Borne and Enteric Diseases, Centers for Disease Control and Prevention, Bldg 22, Rm 14, 4770 Burford Highway, Atlanta, GA 30341, USA
    Exp Parasitol 124:80-9. 2010
  4. ncbi Taxonomy and species delimitation in Cryptosporidium
    Ronald Fayer
    Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, USA
    Exp Parasitol 124:90-7. 2010
  5. ncbi Genetic characterizations of Cryptosporidium spp. and Giardia duodenalis in humans in Henan, China
    Rongjun Wang
    College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China
    Exp Parasitol 127:42-5. 2011
  6. ncbi Molecular characterisation of species and genotypes of Cryptosporidium and Giardia and assessment of zoonotic transmission
    Lihua Xiao
    Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Int J Parasitol 38:1239-55. 2008
  7. pmc Extended outbreak of cryptosporidiosis in a pediatric hospital, China
    Yaoyu Feng
    East China University of Science and Technology, Shanghai, People s Republic of China
    Emerg Infect Dis 18:312-4. 2012
  8. ncbi Multilocus phylogenetic analysis of Cryptosporidium andersoni (Apicomplexa) isolated from a bactrian camel (Camelus bactrianus) in China
    Rongjun Wang
    The College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, The People s Republic of China
    Parasitol Res 102:915-20. 2008
  9. pmc A genome-sequence survey for Ascogregarina taiwanensis supports evolutionary affiliation but metabolic diversity between a Gregarine and Cryptosporidium
    Thomas J Templeton
    Department of Microbiology and Immunology, Weill Cornell Medical College, USA
    Mol Biol Evol 27:235-48. 2010
  10. pmc Cryptosporidium genotype and subtype distribution in raw wastewater in Shanghai, China: evidence for possible unique Cryptosporidium hominis transmission
    Yaoyu Feng
    School of Resource and Environmental Engineering, East China University of Science and Technology, Shanghai 200237, China
    J Clin Microbiol 47:153-7. 2009

Detail Information

Publications332 found, 100 shown here

  1. ncbi Cryptosporidium infection in domestic geese (Anser anser f. domestica) detected by in-situ hybridization
    S Chvala
    Department of Pathobiology, Institute of Pathology and Forensic Veterinary Medicine, Veterinarplatz 1, A 1210 Vienna, Austria
    J Comp Pathol 134:211-8. 2006
    An in-situ hybridization (ISH) procedure was developed for the detection of Cryptosporidium sp. in paraffin wax-embedded tissues with a digoxigenin-labelled probe targeting the 18S rRNA...
  2. ncbi Molecular epidemiology of Cryptosporidium in humans and cattle in The Netherlands
    Peter R Wielinga
    National Institute for Public Health and the Environment RIVM, Centre for Infectious Disease Control CIb, Laboratory for Zoonoses and Environmental Microbiology LZO, Antonie van Leeuwenhoeklaan 9, Bilthoven, The Netherlands
    Int J Parasitol 38:809-17. 2008
    The protozoan parasite Cryptosporidium is found world-wide and can cause disease in both humans and animals...
  3. ncbi Molecular epidemiology of cryptosporidiosis: an update
    Lihua Xiao
    Division of Parasitic Diseases, National Center for Zoonotic, Vector Borne and Enteric Diseases, Centers for Disease Control and Prevention, Bldg 22, Rm 14, 4770 Burford Highway, Atlanta, GA 30341, USA
    Exp Parasitol 124:80-9. 2010
    Molecular tools have been developed to detect and differentiate Cryptosporidium at the species/genotype and subtype levels. These tools have been increasingly used in characterizing the transmission of Cryptosporidium spp...
  4. ncbi Taxonomy and species delimitation in Cryptosporidium
    Ronald Fayer
    Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, USA
    Exp Parasitol 124:90-7. 2010
    Amphibians, reptiles, birds and mammals serve as hosts for 19 species of Cryptosporidium. All 19 species have been confirmed by morphological, biological, and molecular data...
  5. ncbi Genetic characterizations of Cryptosporidium spp. and Giardia duodenalis in humans in Henan, China
    Rongjun Wang
    College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China
    Exp Parasitol 127:42-5. 2011
    b>Cryptosporidium and Giardia infections are common causes of diarrhea worldwide...
  6. ncbi Molecular characterisation of species and genotypes of Cryptosporidium and Giardia and assessment of zoonotic transmission
    Lihua Xiao
    Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Int J Parasitol 38:1239-55. 2008
    The molecular characterisation of species and genotypes of Cryptosporidium and Giardia is essential for accurately identifying organisms and assessing zoonotic transmission...
  7. pmc Extended outbreak of cryptosporidiosis in a pediatric hospital, China
    Yaoyu Feng
    East China University of Science and Technology, Shanghai, People s Republic of China
    Emerg Infect Dis 18:312-4. 2012
    Four Cryptosporidium spp. and 6 C. hominis subtypes were isolated from 102 of 6,284 patients in 3 pediatric hospitals in People's Republic of China. A cryptosporidiosis outbreak was identified retrospectively...
  8. ncbi Multilocus phylogenetic analysis of Cryptosporidium andersoni (Apicomplexa) isolated from a bactrian camel (Camelus bactrianus) in China
    Rongjun Wang
    The College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, The People s Republic of China
    Parasitol Res 102:915-20. 2008
    This is the first report of cryptosporidiosis in a bactrian camel (Camelus bactrianus) in China. Two Cryptosporidium isolates derived from the same bactrian camel (3-year-old) in November 2005 and April 2006 were characterized using ..
  9. pmc A genome-sequence survey for Ascogregarina taiwanensis supports evolutionary affiliation but metabolic diversity between a Gregarine and Cryptosporidium
    Thomas J Templeton
    Department of Microbiology and Immunology, Weill Cornell Medical College, USA
    Mol Biol Evol 27:235-48. 2010
    ..herein describe both features unique to this early diverging apicomplexan and properties that unite it with Cryptosporidium, the Coccidia, and the Apicomplexa...
  10. pmc Cryptosporidium genotype and subtype distribution in raw wastewater in Shanghai, China: evidence for possible unique Cryptosporidium hominis transmission
    Yaoyu Feng
    School of Resource and Environmental Engineering, East China University of Science and Technology, Shanghai 200237, China
    J Clin Microbiol 47:153-7. 2009
    To identify the genotype and subtype distributions of Cryptosporidium oocysts in domestic wastewater in Shanghai, China, and to facilitate the characterization of the endemic transmission of cryptosporidiosis, raw domestic wastewater ..
  11. ncbi Genetic analysis of Cryptosporidium from 2414 humans with diarrhoea in England between 1985 and 2000
    F Leoni
    Health Protection Agency Centre for Infections, 61 Colindale Avenue, London NW9 5EQ, UK
    J Med Microbiol 55:703-7. 2006
    The characterization of Cryptosporidium using DNA extracted from whole faecal samples collected from 2414 humans with diarrhoea in England between 1985 and 2000 where cryptosporidial oocysts were detected using conventional methods is ..
  12. ncbi Cryptosporidium species in HIV-infected individuals in India: an overview
    Sitara Swarna Rao Ajjampur
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore 632002, Tamil Nadu, India
    Natl Med J India 21:178-84. 2008
    b>Cryptosporidium spp. are a major cause of diarrhoea in developing countries mainly affecting children and HIV-infected individuals with low CD4 counts...
  13. ncbi Cryptosporidium
    O Sunnotel
    Centre for Molecular Biosciences, School of Biomedical Sciences, University of Ulster, Coleraine, CO, Londonderry, UK
    Lett Appl Microbiol 43:7-16. 2006
    This review discusses characteristics of the genus Cryptosporidium and addresses the pathogenesis, reservoirs, public health significance and current applications for the detection and typing of this important pathogen...
  14. ncbi Prevalence and molecular characterisation of Cryptosporidium and Giardia species in pre-weaned sheep in Australia
    Rongchang Yang
    Division of Veterinary and Biomedical Sciences, Murdoch University, Murdoch, Western Australia 6150, Australia
    Vet Parasitol 161:19-24. 2009
    ..sheep from 5 different farms in the south west of Western Australia were screened for the presence of Cryptosporidium and Giardia using PCR...
  15. pmc Occurrence, source, and human infection potential of cryptosporidium and Giardia spp. in source and tap water in shanghai, china
    Yaoyu Feng
    State Key Laboratory of Bioreactor Engineering, School of Resource and Environmental Engineering, East China University of Science and Technology, Shanghai, China
    Appl Environ Microbiol 77:3609-16. 2011
    Genotyping studies on the source and human infection potential of Cryptosporidium oocysts in water have been almost exclusively conducted in industrialized nations...
  16. ncbi Cryptosporidium andersoni is the predominant species in post-weaned and adult dairy cattle in China
    Rongjun Wang
    The College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou, China
    Parasitol Int 60:1-4. 2011
    ..samples from 22 dairy cattle farms in ten prefectures in Henan Province were examined for the presence of Cryptosporidium oocysts. The overall prevalence of Cryptosporidium was 7.9%, with the highest infection rate (11...
  17. ncbi Diversity in mitochondrial metabolic pathways in parasitic protists Plasmodium and Cryptosporidium
    Tatsushi Mogi
    Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo, Japan
    Parasitol Int 59:305-12. 2010
    ..Mitosomes of Cryptosporidium parvum and Cryptosporidium hominis (human intestine parasites) lack mtDNA, pyruvate dehydrogenase, TCA cycle ..
  18. pmc Cyclospora papionis, Cryptosporidium hominis, and human-pathogenic Enterocytozoon bieneusi in captive baboons in Kenya
    Wei Li
    Division of Foodborne, Waterborne and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Building 23, Mail Stop D 66, 1600 Clifton Road, Atlanta, GA 30333, USA
    J Clin Microbiol 49:4326-9. 2011
    Cyclospora papionis, Cryptosporidium hominis, and Enterocytozoon bieneusi were detected in 42 (17.9%), 6 (2.6%), and 29 (12.3%) of 235 newly captured baboons in Kenya, respectively. Most C. hominis subtypes and E...
  19. ncbi Treatment of cryptosporidiosis: do we know what we think we know?
    Miguel M Cabada
    Infectious Disease Division, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, USA
    Curr Opin Infect Dis 23:494-9. 2010
    ..Therefore, familiarity with key features of current management tools is important. We discuss diagnostic and therapeutic aspects of cryptosporidiosis focusing on evidence behind the medications available to date...
  20. ncbi Experimental infection of cats with Tritrichomonas foetus
    J L Gookin
    Department of Anatomy, Physiological Sciences and Radiology, College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA
    Am J Vet Res 62:1690-7. 2001
    ..To determine whether infection with Tritrichomonas foetus causes diarrhea in specific-pathogen-free or Cryptosporidium coinfected cats...
  21. ncbi Cryptosporidium ubiquitum n. sp. in animals and humans
    Ronald Fayer
    Environmental Microbial and Food Safety Laboratory, Animal and Natural Resources Institute, Agricultural Research Service, United States Department of Agriculture, 10300 Baltimore Avenue, Beltsville, MD 20705, USA
    Vet Parasitol 172:23-32. 2010
    A new species, Cryptosporidium ubiquitum, previously identified as the Cryptosporidium cervine genotype and infrequently as the cervid, W4 or genotype 3 genotype, is described...
  22. ncbi Multilocus genotyping of Cryptosporidium and Giardia in non-outbreak related cases of diarrhoea in human patients in Belgium
    T Geurden
    Laboratory of Veterinary Parasitology, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Parasitology 136:1161-8. 2009
    Stool samples from Belgian patients suffering from abdominal pain and/or diarrhoea were examined for Cryptosporidium and Giardia...
  23. ncbi Molecular and phylogenetic characterization of Cryptosporidium and Giardia from pigs and cattle in Denmark
    R B Langkjaer
    Department of Veterinary Diagnostics and Research, Danish Institute for Food and Veterinary Research, Bulowsvej 27, DK 1790 Copenhagen V, Denmark
    Parasitology 134:339-50. 2007
    The genetic diversity of Cryptosporidium spp. and Giardia duodenalis from dairy cattle and pigs in Denmark was determined in the present study...
  24. pmc Distribution of cryptosporidium genotypes in storm event water samples from three watersheds in New York
    Jianlin Jiang
    Division of Parasitic Disease, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Building 22, Mail Stop F 12, 4770 Buford Highway, Atlanta, GA 30341 3717, USA
    Appl Environ Microbiol 71:4446-54. 2005
    To assess the source and public health significance of Cryptosporidium oocyst contamination in storm runoff, a PCR-restriction fragment length polymorphism technique based on the small-subunit rRNA gene was used in the analysis of 94 ..
  25. pmc Intestinal parasitic infections in relation to HIV/AIDS status, diarrhea and CD4 T-cell count
    Shimelis Assefa
    Department of Medical Laboratory Science, Gondar University, PO Box 196 Gondar, Ethiopia
    BMC Infect Dis 9:155. 2009
    ..Hence, this study was undertaken to determine the prevalence of intestinal parasitic infection among people with and without HIV infection and its association with diarrhea and CD4 T-cell count...
  26. pmc Cryptosporidium species and subtypes and clinical manifestations in children, Peru
    Vitaliano A Cama
    Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Emerg Infect Dis 14:1567-74. 2008
    To determine whether clinical manifestations are associated with genotypes or subtypes of Cryptosporidium spp., we studied a 4-year longitudinal birth cohort of 533 children in Peru...
  27. ncbi Re-description of Cryptosporidium cuniculus Inman and Takeuchi, 1979 (Apicomplexa: Cryptosporidiidae): morphology, biology and phylogeny
    Guy Robinson
    UK Cryptosporidium Reference Unit, Public Health Wales, Microbiology ABM, Swansea, UK
    Int J Parasitol 40:1539-48. 2010
    To provide re-description of Cryptosporidium cuniculus Inman and Takeuchi, 1979 (synonymous with rabbit genotype), a species closely related to Cryptosporidium hominis, the morphology, natural and experimental host specificity, and ..
  28. pmc Epidemiology and clinical features of Cryptosporidium infection in immunocompromised patients
    Paul R Hunter
    School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, United Kingdom
    Clin Microbiol Rev 15:145-54. 2002
    b>Cryptosporidium spp. are a major cause of diarrheal disease in both immunocompetent and immunodeficient individuals. They also cause waterborne disease in both the United States and United Kingdom...
  29. ncbi Coprological survey in pet reptiles in Italy
    R Papini
    Dipartimento di Patologia Animale, Profilassi e Igiene degli Alimenti, Universita di Pisa, Viale delle Piagge 2, 56124 Pisa, Italy
    Vet Rec 169:207. 2011
    ..direct smear and faecal flotation, while direct immunofluorescence assays were used to reveal the presence of Cryptosporidium oocysts and Giardia cysts. Overall, 57.4 per cent of the reptiles were harbouring intestinal parasites...
  30. ncbi Cryptosporidiosis: biology, pathogenesis and disease
    Saul Tzipori
    Division of Infectious Diseases, Tufts University School of Veterinary Medicine, North Grafton, MA 01536, USA
    Microbes Infect 4:1047-58. 2002
    ..b>Cryptosporidium infects all four classes of vertebrates and most likely all mammalian species...
  31. pmc Genotype analysis of Cryptosporidium spp. prevalent in a rural village in Hwasun-gun, Republic of Korea
    Jae Hwan Park
    Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine, and Institute of Endemic Diseases, Seoul National University Medical Research Center, Seoul, Korea
    Korean J Parasitol 44:27-33. 2006
    Two species of Cryptosporidium are known to infect man; C. hominis which shows anthroponotic transmission between humans, and C. parvum which shows zoonotic transmission between animals or between animals and man...
  32. ncbi Wide geographic distribution of Cryptosporidium bovis and the deer-like genotype in bovines
    Yaoyu Feng
    Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Vet Parasitol 144:1-9. 2007
    ..in the United States reported that approximately 85% of pre-weaned dairy calves were infected with zoonotic Cryptosporidium parvum, whereas only 1-2% of post-weaned calves and 1-2-year-old heifers were infected with this species...
  33. ncbi PCR amplification and sequence analyses of ITS-1 rDNA from Cryptosporidium andersoni in dairy cattle
    Rongqiong Zhou
    Department of Veterinary Parasitology, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China
    Parasitol Res 100:1135-8. 2007
    The internal transcribed spacer 1 (ITS-1) of the ribosomal DNA (rDNA) from GD, HN, and AH strains of Cryptosporidium andersoni was amplified and sequenced to assess whether the ITS-1 rDNA could be used as genetic markers of C...
  34. ncbi Genotypes and subtypes of Cryptosporidium spp. in neonatal calves in Northern Ireland
    Heather P Thompson
    School of Biomedical Science, Faculty of Life and Health Sciences, University of Ulster, Coleraine, Northern Ireland, UK
    Parasitol Res 100:619-24. 2007
    b>Cryptosporidium spp. in diarrheic calves less than 30 days old from farms across Northern Ireland were examined over a year period by microscopic, genotyping, and subtyping techniques to characterize the transmission dynamics...
  35. ncbi Prevalence and genotyping of Cryptosporidium species from farm animals in Mongolia
    Byambaa Burenbaatar
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, 080 8555, Obihiro, Hokkaido, Japan
    Parasitol Res 102:901-5. 2008
    The presence of Cryptosporidium oocysts in 460 animals (439 cattle, 16 kids, and 5 sheep) of Tuv-aimak Mongolian district was investigated by IFT. Cryptosporidium oocysts were found in 116 (26.4%) cattle...
  36. pmc Genetic characterization and transmission cycles of Cryptosporidium species isolated from humans in New Zealand
    James J Learmonth
    Protozoa Research Unit, Institute of Molecular Biosciences, Massey University, Private Bag 11 222, Palmerston North, New Zealand
    Appl Environ Microbiol 70:3973-8. 2004
    Little is known about the genetic characteristics, distribution, and transmission cycles of Cryptosporidium species that cause human disease in New Zealand...
  37. ncbi Giardia and Cryptosporidium in Canadian farm animals
    M E Olson
    Gastrointestinal Research Group, University of Calgary, Alta, Canada
    Vet Parasitol 68:375-81. 1997
    Giardia intestinalis and Cryptosporidium spp. are commonly identified intestinal pathogens in humans and animals...
  38. pmc Cryptosporidium spp. in wild, laboratory, and pet rodents in china: prevalence and molecular characterization
    Chaochao Lv
    College of Animal Science and Veterinary Medicine, Henan Agricultural University, No 95 Wenhua Road, Zhengzhou 450002, China
    Appl Environ Microbiol 75:7692-9. 2009
    To understand the prevalence of Cryptosporidium infection in rodents in China and to assess the potential role of rodents as a source for human cryptosporidiosis, 723 specimens from 18 rodent species were collected from four provinces of ..
  39. pmc Characterization of Cryptosporidium meleagridis of human origin passaged through different host species
    Donna E Akiyoshi
    Department of Biomedical Sciences, Tufts University School of Veterinary Medicine, 200 Westboro Road, North Grafton, MA 01536, USA
    Infect Immun 71:1828-32. 2003
    b>Cryptosporidium meleagridis, a protozoon first observed in turkeys, has been linked by several investigators to cryptosporidiosis in humans. C...
  40. ncbi Cryptosporidium hominis n. sp. (Apicomplexa: Cryptosporidiidae) from Homo sapiens
    Una M Morgan-Ryan
    Division of Veterinary and Biomedical Sciences, Murdoch University, Murdoch, Western Australia 6150
    J Eukaryot Microbiol 49:433-40. 2002
    The structure and infectivity of the oocysts of a new species of Cryptosporidium from the feces of humans are described. Oocysts are structurally indistinguishable from those of Cryptosporidium parvum...
  41. ncbi The homologous and interspecies transmission of Cryptosporidium parvum and Cryptosporidium meleagridis
    Gh Darabus
    Faculty of Veterinary Medicine in Timisoara, Department of Parasitology, Calea Aradului 119, Timisoara 1900, Romania
    Pol J Vet Sci 6:225-8. 2003
    ..infections have been performed in several mammals and birds to determine the host's specificity for Cryptosporidium parvum (of human and bovine origin) and for Cryptosporidium meleagridis (isolated from broiler chicken)...
  42. pmc Sheep may not be an important zoonotic reservoir for Cryptosporidium and Giardia parasites
    Una M Ryan
    Division of Health Sciences, School of Veterinary and Biomedical Science, Murdoch University, Murdoch, Western Australia, Australia 6150
    Appl Environ Microbiol 71:4992-7. 2005
    Little is known of the prevalence of Cryptosporidium and Giardia parasites in sheep and the genotypes that they harbor, although potentially sheep may contribute significantly to contamination of watersheds...
  43. ncbi Cryptosporidium oocysts in Ghanaian AIDS patients with diarrhoea
    A Adjei
    Department of Pathology, University of Ghana Medical School, Korle Bu, Accra
    East Afr Med J 80:369-72. 2003
    ..infections in acquired immunodeficiency syndrome patients (AIDS) with chronic diarrhoea have been reported in several African countries, there is no information regarding cryptosporidial diarrhoea in Ghanaian AIDS patients...
  44. pmc Campylobacter spp., Giardia spp., Cryptosporidium spp., noroviruses, and indicator organisms in surface water in southwestern Finland, 2000-2001
    Ari Hörman
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland
    Appl Environ Microbiol 70:87-95. 2004
    ..Giardia spp., Cryptosporidium spp...
  45. ncbi First report of Cryptosporidium deer-like genotype in Malaysian cattle
    N Abdul Halim
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
    Vet Parasitol 152:325-9. 2008
    ..1 and 6 months old were collected per rectum from 5 farms around Petaling District in Selangor, Malaysia for Cryptosporidium species detection and genotyping investigation...
  46. ncbi Cryptosporidium, Giardia and Enterocytozoon bieneusi in cats from Bogota (Colombia) and genotyping of isolates
    Monica Santin
    Environmental Microbial Safety Laboratory, Animal and Natural Resources Institute, Agricultural Research Service, United States Department of Agriculture, Building 173, BARC East, 10300 Baltimore Avenue, Beltsville, MD 20705, USA
    Vet Parasitol 141:334-9. 2006
    The prevalence of Cryptosporidium, Giardia, and Enterocytozoon bieneusi in cats from Bogota (Colombia) was determined from fecal specimens and scrapings of duodenal and ileal mucosa screened by PCR...
  47. ncbi The epidemiology of sporadic human infections with unusual cryptosporidia detected during routine typing in England and Wales, 2000-2008
    K Elwin
    UK Cryptosporidium Reference Unit, Public Health Wales Microbiology, Singleton Hospital, Swansea, UK
    Epidemiol Infect 140:673-83. 2012
    ..of 14 469 isolates from human cryptosporidiosis cases between 2000 and 2008 revealed that 7439 (51·4%) were Cryptosporidium (C.) hominis, 6372 (44·0%) C. parvum, 51 (0·4%) both C. hominis and C...
  48. ncbi Cryptosporidium spp. in pet birds: genetic diversity and potential public health significance
    Meng Qi
    College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China
    Exp Parasitol 128:336-40. 2011
    To characterize the prevalence and assess the zoonotic transmission burden of Cryptosporidium species/genotypes in pet birds in Henan, China, 434 fecal samples were acquired from 14 families of birds in pet shops...
  49. ncbi Evaluation of enzyme immunoassay techniques for diagnosis of the most common intestinal protozoa in fecal samples
    Maha R Gaafar
    Parasitology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt
    Int J Infect Dis 15:e541-4. 2011
    ..EIAs) Triage parasite panel and TechLab Entamoeba histolytica II in detecting Giardia intestinalis, Cryptosporidium sp, and Entamoeba histolytica in fecal samples in comparison to microscopy, and in differentiating Entamoeba ..
  50. ncbi The zoonotic potential of Giardia and Cryptosporidium in Norwegian sheep: a longitudinal investigation of 6 flocks of lambs
    L J Robertson
    Parasitology Laboratory, Department of Food Safety and Infection Biology, Norwegian School of Veterinary Science, Postbox 8146 Dep, 0033 Oslo, Norway
    Vet Parasitol 171:140-5. 2010
    ..occasions during spring/summer 2008 (approximately 550 samples collected at each occasion) were examined for Cryptosporidium oocysts and Giardia cysts by immunofluorescent antibody test...
  51. ncbi Prevalence of Cryptosporidium infection in camels (Camelus dromedarius) in a slaughterhouse in Iran
    S M Razawi
    Department of Parasitology, Veterinary School, Shiraz University, Shiraz, Iran
    Trop Biomed 26:267-73. 2009
    ..is acknowledged as a potential source of contamination, little is known with regards to the prevalence of Cryptosporidium in this population except a case report on the occurrence of this infection in a bactrian camel (Camelus ..
  52. pmc Inferences about the global population structures of Cryptosporidium parvum and Cryptosporidium hominis
    Sultan Tanriverdi
    Tufts Cummings School of Veterinary Medicine, Division of Infectious Diseases, North Grafton, MA 01536, USA
    Appl Environ Microbiol 74:7227-34. 2008
    b>Cryptosporidium parvum and Cryptosporidium hominis are two related species of apicomplexan protozoa responsible for the majority of human cases of cryptosporidiosis...
  53. ncbi Giardia duodenalis and Cryptosporidium spp. in the intestinal contents of ringed seals (Phoca hispida) and bearded seals (Erignathus barbatus) in Nunavik, Quebec, Canada
    Brent R Dixon
    Microbiology Research Division, Food Directorate, Health Canada, Banting Research Centre 2204E, 251 Sir Frederick Banting Driveway, Ottawa, Ontario, Canada
    J Parasitol 94:1161-3. 2008
    The prevalence of Giardia duodenalis and Cryptosporidium spp. was determined for ringed and bearded seals harvested for food in the Nunavik region in northern Quebec, Canada. Flow cytometric results demonstrated that G...
  54. pmc A hundred-year retrospective on cryptosporidiosis
    Saul Tzipori
    Tufts Cummings School of Veterinary Medicine, Division of Infectious Diseases, North Grafton, MA 01536, USA
    Trends Parasitol 24:184-9. 2008
    Tyzzer discovered the genus Cryptosporidium a century ago, and for almost 70 years cryptosporidiosis was regarded as an infrequent and insignificant infection that occurred in the intestines of vertebrates and caused little or no disease...
  55. ncbi Genotype and subtype analyses of Cryptosporidium isolates from cattle in Hungary
    Judit Plutzer
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080 8555, Japan
    Vet Parasitol 146:357-62. 2007
    ..on 52 farms from different counties in Hungary to investigate the species, genotypes and subtypes of Cryptosporidium in calves...
  56. ncbi Prevalence and molecular characterization of Cryptosporidium and Giardia species and genotypes in sheep in Maryland
    Monica Santin
    Environmental Microbial Safety Laboratory, Animal and Natural Resources Institute, Agricultural Research Service, United States Department of Agriculture, Building 173, BARC East, 10300 Baltimore Avenue, Beltsville, MD 20705, USA
    Vet Parasitol 146:17-24. 2007
    In the United Kingdom and Australia sheep have been implicated as sources of Cryptosporidium and Giardia that infect humans, but no such studies have been conducted in North America...
  57. ncbi Cryptic parasite revealed improved prospects for treatment and control of human cryptosporidiosis through advanced technologies
    Aaron R Jex
    Department of Veterinary Science, The University of Melbourne, Werribee, Victoria, Australia
    Adv Parasitol 77:141-73. 2011
    b>Cryptosporidium is an important genus of parasitic protozoa of humans and other vertebrates and is a major cause of intestinal disease globally...
  58. ncbi Microsporidiosis in HIV-positive children in Madrid (Spain)
    C del Aguila
    Sec Parasitology, Fac CCEE y Técnicas, Univ San Pablo CEU, Madrid, Spain
    J Eukaryot Microbiol 44:84S-85S. 1997
    ..Enteric parasites were identified in 32.5% of the children. Cryptosporidium sp. was the most common parasite encountered (14.4%), followed by Blastocytis sp. (9...
  59. ncbi Age-related and housing-dependence of Cryptosporidium infection of calves from dairy and beef herds in South Bohemia, Czech Republic
    Martin Kvac
    Department of Medical and Veterinary Parasitology, Institute of Parasitology, Academy of Sciences of the Czech Republic, Branisovska 31, 370 05 Ceske Budejovice, Czech Republic
    Vet Parasitol 137:202-9. 2006
    ..The farms were visited over four consecutive years (from 2002 to 2005). The prevalence of Cryptosporidium in pre-weaned (animals until second month of age) and post-weaned (animals from the third month of age) ..
  60. ncbi Prevalence of species and genotypes of Cryptosporidium found in 1-2-year-old dairy cattle in the eastern United States
    Ronald Fayer
    Environmental Microbial Safety Laboratory, Animal and Natural Resources Institute, Agricultural Research Service, United States Department of Agriculture, Building 173, BARC East, 10300 Baltimore Avenue, Beltsville, MD 20705, USA
    Vet Parasitol 135:105-12. 2006
    The prevalence of Cryptosporidium species in 1-2-year-old heifers was determined for 571 animals on 14 dairy farms in seven states on the East Coast of the United States...
  61. ncbi Identification of rare and novel Cryptosporidium GP60 subtypes in human isolates from Jordan
    Nawal Hijjawi
    Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, The Hashemite University, P O Box 150459, Zarqa 13115, Jordan
    Exp Parasitol 125:161-4. 2010
    Little is known about the epidemiology of Cryptosporidium in Jordan and no genotyping studies have been conducted on Cryptosporidium isolates from humans or animals from Jordan...
  62. ncbi Molecular epidemiology of Cryptosporidium subtypes in cattle in England
    Emily J Brook
    Department of Veterinary Clinical Science, University of Liverpool, Neston, UK
    Vet J 179:378-82. 2009
    Samples of Cryptosporidium spp., collected in a cross-sectional study of calves (median age 26 days) from 41 farms in Cheshire, UK, underwent molecular typing...
  63. ncbi Cryptosporidium tyzzeri n. sp. (Apicomplexa: Cryptosporidiidae) in domestic mice (Mus musculus)
    Xupeng Ren
    College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, PR China
    Exp Parasitol 130:274-81. 2012
    The Cryptosporidium in the small intestine of domestic mice (Mus musculus) was initially described as Cryptosporidium parvum...
  64. ncbi Zoonotic cryptosporidiosis in the UK - challenges for control
    R M Chalmers
    UK Cryptosporidium Reference Unit, Public Health Wales Microbiology ABM, Singleton Hospital, Swansea, UK
    J Appl Microbiol 109:1487-97. 2010
    The protozoan parasite Cryptosporidium infects all classes of vertebrates. Of the major human pathogenic species, Cryptosporidium parvum and Cryptosporidium hominis predominate in the UK...
  65. pmc Unusual Cryptosporidium genotypes in human cases of diarrhea
    Guy Robinson
    UK Cryptosporidium Reference Unit, Swansea, UK
    Emerg Infect Dis 14:1800-2. 2008
    Several Cryptosporidium spp. are known to infect humans, but most cases of illness are caused by Cryptosporidium hominis or C. parvum...
  66. ncbi Genetic polymorphism in Cryptosporidium species: an update
    Judit Plutzer
    National Institute of Environmental Health, Department of Water Hygiene, Gyali ut 2 6, Budapest H 1096, Hungary
    Vet Parasitol 165:187-99. 2009
    ..Genetic polymorphism within Cryptosporidium species is being detected at a continuously growing rate, owing to the widespread use of modern molecular ..
  67. ncbi Variation in Cryptosporidium: towards a taxonomic revision of the genus
    U M Morgan
    World Health Organisation Collaborating Centre for the Molecular Epidemiology of Parasitic Infections, and State Agricultural Biotechnology Centre, Murdoch University, Australia
    Int J Parasitol 29:1733-51. 1999
    b>Cryptosporidium is an important cause of enteric disease in humans and other animals...
  68. pmc Molecular characterization of Cryptosporidium isolates obtained from humans in France
    K Guyot
    Ecologie du Parasitisme, Institut Pasteur de Lille, BP 245, 59019 Lille, France
    J Clin Microbiol 39:3472-80. 2001
    b>Cryptosporidium parvum is usually considered the agent of human cryptosporidiosis...
  69. ncbi Prevalence of Cryptosporidium species and genotypes in mature dairy cattle on farms in eastern United States compared with younger cattle from the same locations
    Ronald Fayer
    Environmental Microbial Safety Laboratory, Animal and Natural Resources Institute, Agricultural Research Service, United States Department of Agriculture, BARC East, 10300 Baltimore Avenue, Beltsville, Maryland 20705, USA
    Vet Parasitol 145:260-6. 2007
    ..New York, Pennsylvania, Maryland, Virginia, North Carolina, and Florida were examined for the presence of Cryptosporidium oocysts. Oocysts were concentrated from 15 g of feces from each cow and DNA was extracted...
  70. pmc Identification of a high diversity of Cryptosporidium species genotypes and subtypes in a pediatric population in Nigeria
    Sile F Molloy
    Department of Zoology, School of Natural Sciences, Trinity College Dublin, Ireland
    Am J Trop Med Hyg 82:608-13. 2010
    A longitudinal study was conducted to determine the epidemiology of Cryptosporidium in 1,636 children in Nigeria. Oocyst prevalence ranged from 15.6% to 19.6% over one year. Cryptosporidium hominis (34), C. parvum (25), C. parvum/C...
  71. pmc Multi-locus analysis of human infective Cryptosporidium species and subtypes using ten novel genetic loci
    Maha Bouzid
    Biomedical Research Centre, School of Medicine, Health Policy and Practice, University of East Anglia, Norwich NR4 7TJ, UK
    BMC Microbiol 10:213. 2010
    b>Cryptosporidium is a protozoan parasite that causes diarrheal illness in a wide range of hosts including humans. Two species, C. parvum and C. hominis are of primary public health relevance...
  72. pmc Multisite study of cryptosporidiosis in children with diarrhea in India
    Sitara Swarna Rao Ajjampur
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore 632004, India
    J Clin Microbiol 48:2075-81. 2010
    b>Cryptosporidium spp., a common cause of diarrhea in children, were investigated in the first multisite study in India...
  73. ncbi Genetic diversity of Cryptosporidium spp. in cattle in Michigan: implications for understanding the transmission dynamics
    Michael M Peng
    Division of Parasitic Diseases, Center for Disease Control and Prevention, Atlanta, GA 30341, USA
    Parasitol Res 90:175-80. 2003
    Epidemiological and molecular data on 248 bovine, 17 human, and 16 water samples of Cryptosporidium spp. collected from the lower peninsula of Michigan between 1997 and 2000 were analysed...
  74. pmc Prevalence, genetic characteristics, and zoonotic potential of Cryptosporidium species causing infections in farm rabbits in China
    Ke Shi
    College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, People s Republic of China
    J Clin Microbiol 48:3263-6. 2010
    ..The average infection rate of Cryptosporidium was 3.4% (37/1,081 samples)...
  75. ncbi Molecular detection of Cryptosporidium cuniculus in rabbits in Australia
    Matthew J Nolan
    Department of Veterinary Science, University of Melbourne, Werribee, Victoria, Australia
    Infect Genet Evol 10:1179-87. 2010
    In the United Kingdom, rabbits have been reported to harbour genotypes of Cryptosporidium (now recognized as C. cuniculus) identical to those from human patients exhibiting symptoms of cryptosporidiosis...
  76. ncbi Molecular characterization of Cryptosporidium isolates from human and bovine using 18s rRNA gene in Shahriar county of Tehran, Iran
    Majid Pirestani
    Parasitology Department, School of Medical Science, Tarbiat Modares University, Tehran, Iran
    Parasitol Res 103:467-72. 2008
    ..Although in recent years molecular investigations on Cryptosporidium have increased, no data are available on Iran in this regard...
  77. pmc Classification of Cryptosporidium species from patients with sporadic cryptosporidiosis by use of sequence-based multilocus analysis following mutation scanning
    Aaron R Jex
    Department of Veterinary Science, The University of Melbourne, Werribee, Victoria 3030, Australia
    J Clin Microbiol 46:2252-62. 2008
    In the present study, we analyzed genetic variation in Cryptosporidium species from humans (n = 62) with clinical cryptosporidiosis in South Australia...
  78. ncbi Prevalence and phylogenetic analysis of Cryptosporidium in pigs in eastern China
    F Chen
    College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China
    Zoonoses Public Health 54:393-400. 2007
    ..modified acid-fast staining technique (MAFS) and observed by light and phase contrast microscopy to identify Cryptosporidium oocysts. A total of 178 (12%) positive animals were detected...
  79. ncbi High prevalence of Cryptosporidium bovis and the deer-like genotype in calves compared to mature cows in beef cow-calf operations
    Dawn C Feltus
    Department of Veterinary and Microbiological Sciences, North Dakota State University, Fargo, ND 58105 USA
    Vet Parasitol 151:191-5. 2008
    Recent studies have identified the novel, host adapted Cryptosporidium bovis and the deer-like genotype in dairy cattle from farms in the United States, China, India and Europe...
  80. pmc Development of a multilocus sequence tool for typing Cryptosporidium muris and Cryptosporidium andersoni
    Yaoyu Feng
    State Key Laboratory of Bioreactor Engineering, School of Resource and Environmental Engineering, East China University of Science and Technology, Shanghai, China
    J Clin Microbiol 49:34-41. 2011
    Although widely used for the characterization of the transmission of intestinal Cryptosporidium spp., genotyping tools are not available for C. muris and C. andersoni, two of the most common gastric Cryptosporidium spp. infecting mammals...
  81. ncbi Genetic richness and diversity in Cryptosporidium hominis and C. parvum reveals major knowledge gaps and a need for the application of "next generation" technologies--research review
    Aaron R Jex
    Department of Veterinary Science, The University of Melbourne, Werribee, Victoria 3030, Australia
    Biotechnol Adv 28:17-26. 2010
    b>Cryptosporidium species (apicomplexan protists) are a major cause of diarrhoeal disease (= cryptosporidiosis) in humans worldwide...
  82. pmc UV inactivation of Cryptosporidium hominis as measured in cell culture
    Anne M Johnson
    The Metropolitan Water District of Southern California, Water Quality Laboratory, 700 Moreno Avenue, La Verne, CA 91750, USA
    Appl Environ Microbiol 71:2800-2. 2005
    The Cryptosporidium spp. UV disinfection studies conducted to date have used Cryptosporidium parvum oocysts...
  83. ncbi Minireview: clinical cryptosporidiosis
    Rachel M Chalmers
    Head of UK Cryptosporidium Reference Unit, NPHS Microbiology Swansea, Singleton Hospital, Sketty Lane, Swansea SA2 8QA, UK
    Exp Parasitol 124:138-46. 2010
    b>Cryptosporidium has emerged as an important cause of diarrhoeal illness worldwide, especially amongst young children and patients with immune deficiencies...
  84. pmc Multilocus genotyping of Cryptosporidium sp. isolates from human immunodeficiency virus-infected individuals in South India
    Dheepa Muthusamy
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, 632004, India
    J Clin Microbiol 44:632-4. 2006
    ..b>Cryptosporidium hominis, C. parvum, C. felis, C. muris, and C. meleagridis were identified...
  85. ncbi Distribution of Cryptosporidium subtypes in humans and domestic and wild ruminants in Portugal
    Margarida Alves
    Unidade de Protozoários Oportunistas VIH e Outras Protozooses, Unidade de Parasitologia e Microbiologia Médicas UPMM, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Rua da Junqueira, 96, 1349 008, Lisboa, Portugal
    Parasitol Res 99:287-92. 2006
    To investigate the transmission of cryptosporidiosis in Portugal, Cryptosporidium hominis and Cryptosporidium parvum from HIV-infected patients, cattle, and wild ruminants were characterized by sequence analysis of the 60-kDa ..
  86. ncbi Epidemiology of Cryptosporidium: transmission, detection and identification
    R Fayer
    United States Department of Agriculture, Agricultural Research Institute, LPSI, 10300 Baltimore Avenue, Beltsville, MD 20705, USA
    Int J Parasitol 30:1305-22. 2000
    There are 10 valid species of Cryptosporidium and perhaps other cryptic species hidden under the umbrella of Cryptosporidium parvum...
  87. ncbi Genotype and subtype analyses of Cryptosporidium isolates from dairy calves and humans in Ontario
    L A Trotz-Williams
    Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, ON, N1G 2W1, Canada
    Parasitol Res 99:346-52. 2006
    To assess the importance of dairy cattle as a source of human Cryptosporidium infections in Ontario, Canada, 44 Cryptosporidium isolates from neonatal dairy calves and 11 from sporadic human cases of cryptosporidiosis in the province ..
  88. ncbi Prevalence and molecular characterization of bovine Cryptosporidium in Qazvin province, Iran
    Akbar Keshavarz
    Department of Medical Parasitology and Mycology, Shahid Beheshti University, M C, Tehran, Iran
    Vet Parasitol 160:316-8. 2009
    ..aim of this study was to determine the prevalence, variability with host age, and the genotypes of species of Cryptosporidium in cattle from 15 dairy farms in Qazvin province, Iran...
  89. ncbi Glycoprotein 60 diversity in C. hominis and C. parvum causing human cryptosporidiosis in NSW, Australia
    L S Waldron
    Department of Biological Sciences, Macquarie University, Sydney, NSW 2109, Australia
    Exp Parasitol 122:124-7. 2009
    Management and control of cryptosporidiosis in human requires knowledge of Cryptosporidium species contributing to human disease...
  90. pmc An examination of risk factors associated with beef cattle shedding pathogens of potential zoonotic concern
    B R Hoar
    Department of Population Health and Reproduction, School of Veterinary Medicine, University of California Davis, 95616, USA
    Epidemiol Infect 127:147-55. 2001
    The prevalence of three waterborne zoonotic pathogens (Campylobacter sp., Giardia sp. and Cryptosporidium parvum) in rectal faecal samples from a random sample of adult beef cattle was determined...
  91. ncbi The European rabbit (Oryctolagus cuniculus), a source of zoonotic cryptosporidiosis
    G Robinson
    UK Cryptosporidium Reference Unit, NPHS Microbiology Swansea, Singleton Hospital, Swansea, UK
    Zoonoses Public Health 57:e1-13. 2010
    b>Cryptosporidium spp. have been found in the faeces of over 150 mammalian host species, but the risks to public health from wildlife are poorly understood. In summer 2008, the Cryptosporidium sp...
  92. pmc Prevalence of Giardia cysts and Cryptosporidium oocysts and characterization of Giardia spp. isolated from drinking water in Canada
    P M Wallis
    Hyperion Research Ltd, Medicine Hat, Alberta, Canada
    Appl Environ Microbiol 62:2789-97. 1996
    ..The presence of Cryptosporidium oocysts was also noted, but isolates were not collected for further study...
  93. pmc Development and preliminary evaluation of a loop-mediated isothermal amplification procedure for sensitive detection of cryptosporidium oocysts in fecal and water samples
    Panagiotis Karanis
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Hokkaido 080 8555, Japan
    Appl Environ Microbiol 73:5660-2. 2007
    A loop-mediated isothermal amplification (LAMP) procedure for the detection of Cryptosporidium in environmental and fecal samples was developed and evaluated...
  94. ncbi Genetic classification of Cryptosporidium isolates from humans and calves in Slovenia
    B Soba
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
    Parasitology 135:1263-70. 2008
    To assess the importance of cattle as a source of human cryptosporidial infections in Slovenia, Cryptosporidium isolates from calves and humans with cryptosporidiosis were characterized genetically by direct DNA sequencing, targeting a ..
  95. ncbi Occurrence of Giardia and Cryptosporidium in water supplies of Russia and Bulgaria
    P Karanis
    Medical and Molecular Parasitology Laboratory, University of Cologne, Medical School, Center of Anatomy, Institute II, Joseph Stelzmann Str 9, D 50931 Cologne, Germany
    Environ Res 102:260-71. 2006
    ..water supplies in southern Russia and Bulgaria, in order to estimate the occurrence of Giardia and Cryptosporidium in drinking water resources from these countries...
  96. ncbi Evaluating Cryptosporidium and Giardia concentrations in combined sewer overflow
    Russell D Arnone
    United States Environmental Protection Agency, Urban Watershed Management Branch MS 104, Edison, NJ 08837, USA
    J Water Health 4:157-65. 2006
    Since the first identified Cryptosporidium outbreaks occurred in the 1980s and the massive 1993 Milwaukee, WI outbreak affected more than 400,000 people, the concern over the public health risks linked to protozoan pathogens ..
  97. ncbi Giardia and Cryptosporidium and public health: the epidemiological scenario from the Italian perspective
    Annunziata Giangaspero
    Dipartimento di Scienze delle Produzioni, dell Ingegneria e della Meccanica e dell Economia Applicate ai Sistemi Agro Zootecnici, University of Foggia, 71100, Foggia, Italy
    Parasitol Res 101:1169-82. 2007
    Giardia and Cryptosporidium spp. are protozoa that cause human and animal disease worldwide and often exhibit zoonotic transmission. This review gives ample information concerning the epidemiology of these parasites in Italy, i.e...
  98. ncbi Analysis of serological responses to Cryptosporidium antigen among NHANES III participants
    Floyd J Frost
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87108, USA
    Ann Epidemiol 14:473-8. 2004
    ..NHANES) III participants from seven primary sampling units were tested for serological responses to two Cryptosporidium antigen groups...
  99. ncbi Prevalence and molecular characterization of human and bovine Cryptosporidium isolates in Thailand
    Chadaporn Nuchjangreed
    Medical Science Department, Faculty of Science, Burapha University, Bangsaen, Chon Buri, Thailand
    Parasitol Res 103:1347-53. 2008
    This study was performed to determine the prevalence and genotypes of Cryptosporidium species among HIV patients and cattle in Thailand...
  100. pmc Cryptosporidium muris infection in an HIV-infected adult, Kenya
    Wangeci Gatei
    Liverpool School of Tropical Medicine, United Kingdom
    Emerg Infect Dis 8:204-6. 2002
    We describe a case of Cryptosporidium muris infection in an HIV-infected adult with diarrhea in Kenya. Sequence analysis of an 840-bp region of the 18S rRNA gene locus demonstrated the isolate had 100% nucleotide identity with C...
  101. ncbi Cryptosporidium oocysts in water for human consumption. Comparison of staining methods
    J Rodríguez-Hernández
    Departamento de Microbiologia, Universidad de Salamanca, Spain
    Eur J Epidemiol 10:215-8. 1994
    A study was carried out on the presence of oocysts of Cryptosporidium spp...

Research Grants64

  1. MECHANISM-BASED DRUG SELECTION AND DESIGN: NUCLEOTIDE SA
    Buddy Ullman; Fiscal Year: 2003
    ..the pyrimidine and purine salvage pathways in Toxoplasma gondii and related apicomplexan parasites, including Cryptosporidium, Sarcocystis, and Plasmodium...
  2. Enhanced Membrane Systems for Supplying Quality Drinking Water
    Andrew Feiring; Fiscal Year: 2013
    ..in waterborne disease outbreaks as are noroviruses and the protozoan parasites Giardia intestinalis and Cryptosporidium. Additionally outbreaks of Legionnaires Disease are relatively common, and although these are usually not ..
  3. A Systems Biology Approach to the Model Apicomplexan Toxoplasma gondii
    William J Sullivan Jr; Fiscal Year: 2010
    ..These obligate intracellular parasites include Toxoplasma gondii, Plasmodium species and Cryptosporidium. Toxoplasma gondii is a major opportunistic pathogen of the AIDS epidemic, a cause of birth defects and is ..
  4. Hospital and Household Studies of Respiratory Cryptosporidiosis and Transmission
    Jeffrey K Griffiths; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Human Cryptosporidium (Cr.) transmission has been thought to occur only via fecal-oral, water-, or food-borne routes. We recently found that 35% of Ugandan children with Cr...
  5. The development of probiotic yeast as an inexpensive vaccine delivery platform
    TRACEY JANE LAMB; Fiscal Year: 2013
    ..nature of the immune responses generated will be demonstrated using a mouse model of diarrheal infection, Cryptosporidium parvum. Defined vaccine targets against C. parvum will be expressed by S...
  6. International Workshop on Opportunistic Protists (IWOP-12, 13 and 14)
    Louis M Weiss; Fiscal Year: 2012
    ..IWOP now includes research presentations on Cryptosporidium;the Microsporidia, both causing AIDS associated chronic diarrhea;Toxoplasma gondii, which can cause ..
  7. Genome Sequencer FLX Instrument
    ANNE VIRGINIA KANE; Fiscal Year: 2010
    ..microbiota in a wide range of study populations (children with pneumonia or cystic fibrosis or infected with Cryptosporidium, recipients of bone marrow transplants, patients colonized with antibiotic resistant bacteria, carriers of ..
  8. Multiplexed Detection of Food and Waterborne Pathogens
    Francis Barany; Fiscal Year: 2011
    ..PCR/LDR and RT-PCR/LDR will be used to detect the Category B food and water-borne protozoa (Cryptosporidium parvum, Cyclospora cayatanensis, Entamoeba histolytica, Giardia lamblia and Microsporidia) and viruses (..
  9. Purine Salvage Pathway of Cryptosporidium Parvum
    Buddy Ullman; Fiscal Year: 2012
    ..and pharmacology, this proposal offers an interdisciplinary dissection of the purine salvage pathway of Cryptosporidium parvum, a protozoan parasite that is an opportunistic pathogen of people with AIDS and an NIAID Biodefense ..
  10. Toxoplasma Epigenomics and Gene Expression
    Kami Kim; Fiscal Year: 2013
    ..The genes are also conserved in many other apicomplexan organisms that affect AIDS patients such as Cryptosporidium. Understanding the function of AP2 proteins may lead to new treatments that will prevent of treat T...
  11. Multiplex fluorescence optofluidic microscopy for diagnosis of enteric parasites
    Changhuei Yang; Fiscal Year: 2013
    ..Specifically, we aim to detect Entamoeba, Giardia, Cryptosporidium and Cyclospora, parasites, which pose a public health risk via drinking water supply contamination...
  12. A Heterologous Expression System for Apicomplexa Genes
    JOSE A FERNANDEZ ROBLEDO; Fiscal Year: 2010
    ..Toxoplasma, Cryptosporidium, and Cyclospora are also well known to public health authorities since they pose a threat to immunosuppressed ..
  13. Cholesterol Uptake by Cryptosporidium
    Isabelle Coppens; Fiscal Year: 2010
    ..b>Cryptosporidium infection begins with microbial invasion of small intestinal epithelial cells (enterocytes), in which the ..
  14. Partnership for Detection of Infection by Category B Pathogens
    Frances S Ligler; Fiscal Year: 2011
    ..coli, Shigella, Listeria, Cryptosporidium parvum, Giardia lamblia, and VEE...
  15. Connecticut Emerging Infections Program
    MATTHEW LEWIS CARTTER; Fiscal Year: 2011
    ..b>Cryptosporidium, Cyclospora, E. colt O157 and other Shiga-toxin producing E. coil, Listeria monocytogenes, Salmonella spp...
  16. Dissecting a novel mechanism of drug-induced death in Toxoplasma gondii
    GUSTAVO A ARRIZABALAGA; Fiscal Year: 2013
    ..phylum of obligate intracellular parasites, including Plasmodium falciparum, the causative agent of malaria, Cryptosporidium, which causes gastrointestinal disease, and the category B agent Toxoplasma gondii, which can be pathogenic ..
  17. Identifying cellular and molecular interactions along the pathway to symbiosis
    Elizabeth A Vallen; Fiscal Year: 2012
    ..In addition, analyzing the interaction between these organisms will likely give insight into the interaction of other animals (like humans) with intracellular eukaryotic parasites like Toxoplasma, Plasmodium and Cryptosporidium.
  18. Pathophysiology of cholangiocyte responses to microbial pathogens
    STEVEN P O'HARA; Fiscal Year: 2013
    ..g. lipopolysaccharide) or colonized by pathogenic microorganisms (e.g. Cryptosporidium parvum, a parasitic protozoon and Category B Biodefense pathogen that causes intestinal and biliary ..
  19. Long term Impact and Intervention for Diarrhea in Brazil
    Richard L Guerrant; Fiscal Year: 2013
    ..database includes >1000 individuals of whom 277 are children with diarrhea surveillance) to quantify Cryptosporidium, Giardia, and enteropathic E. coli (EAEC, EPEC, and ETEC)...
  20. Environmental Health Specialist Network
    RICHARD NORMAN DANILA; Fiscal Year: 2013
    ..Special studies to identify the burden of Cryptosporidium, Shiga toxin-producing E...
  21. IMPDH-targeted antibiotics for select agents
    LIZBETH K HEDSTROM; Fiscal Year: 2013
    ..engaged in a medicinal chemistry program to develop IMPDH-targeted drugs for treating the category B parasite Cryptosporidium parvum. We have 'in hand'low nanomolar inhibitors of C...
  22. Calcium Dependent Protein Kinase 1 as a drug target for T. gondii and C. parvum
    ARTHUR CLINTON WHITE; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): New therapeutics are needed for infections caused by Cryptosporidium parvum and Toxoplasma gondii. Calcium dependent protein kinase 1 (CDPK1) of T...
  23. Mucosal Immunity and the Role of TH1 Cytokines in a Model of Cryptosporidiosis
    Jan R Mead; Fiscal Year: 2013
    ..in the US, mainly due to ingestion of water that has been contaminated by the chlorine-resistant pathogen Cryptosporidium. Currently, limited therapeutic agents are available for cryptosporidiosis among immunocompromised patients, ..
  24. Essential Cell Cycle Mechanisms in Toxoplasma
    Michael W White; Fiscal Year: 2013
    ..studies will apply broadly to the growth of other pathogens in this family, such as Plasmodium, Eimeria, and Cryptosporidium, where our knowledge of parasite cell cycle mechanisms is equally deficient...
  25. MYST opportunities for Toxoplasma drug development
    William J Sullivan Jr; Fiscal Year: 2010
    ..the phylum Apicomplexa include some of the most notorious protozoan parasites, such as Plasmodium (malaria), Cryptosporidium (diarrheal disease), and Toxoplasma (toxoplasmic encephalitis)...
  26. Novel approaches to develop a treatment for cryptosporidiosis
    Christopher D Huston; Fiscal Year: 2013
    ..provided by applicant): Cryptosporidiosis, due to intestinal infection with the intracellular parasites Cryptosporidium parvum or C...
  27. Targeting Host and Apicomplexan Isoprenoid Pathways
    Silvia N Moreno; Fiscal Year: 2013
    ..b>Cryptosporidium parvum is responsible for significant disease burden among children in developing countries and it can result ..
  28. Development of IMPDH-Targeted Drugs against Crytosporidium
    LIZBETH K HEDSTROM; Fiscal Year: 2010
    The protozoan parasite Cryptosporidium has caused massive waterborne outbreaks in the U.S, including the 1993 Milwaukee outbreak, where ~400,000 individuals contracted disease, with an economic cost of $31...
  29. Revitalizing Tennessee's Core Environmental Health Programs: Food Safety and Wate
    John R Dunn; Fiscal Year: 2013
    ..With EHS-Net support, the state public health laboratory gained capacity to isolate and speciate Cryptosporidium from stool and environmental field samples...
  30. Immune Response to Cryptosporidiosis in a Birth Cohorot of Children of South Indi
    Honorine D Ward; Fiscal Year: 2012
    ..Boston MA and Christian Medical College, Vellore, India is to investigate the immune response to natural Cryptosporidium spp. infections in children in southern India...
  31. DESIGNING SELECTIVE INHIBITORS OF CALCIUM-DEPENDENT KINASES IN PARASITES
    L David Sibley; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Toxoplasma gondii and Cryptosporidium parvum are important opportunistic pathogens that cause devastating disease in immunocompromised humans...
  32. T. gondii as a model for investigation of Cryptosporidium glycoprotein antigens
    ROBERTA M O apos CONNOR; Fiscal Year: 2010
    b>Cryptosporidium (Cp) is a ubiquitous waterborne pathogen that causes diarrheal disease worldwide. This pathogen causes life-threatening diarrheal disease in immunocompromised hosts, particularly AIDS patients...
  33. O-Glycan Synthesis: Potential Targets for Intervention in Cryptosporidiosis
    Honorine D Ward; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The opportunistic apicomplexan parasite Cryptosporidium (Crypto) causes diarrheal disease worldwide which can be devastating in AIDS patients...
  34. Protein Secretion and Intracellular Survival by Toxoplasma
    L David Sibley; Fiscal Year: 2013
    ..model for many biological features are conserved in other less-easily studied apicomplexan parasites such as Cryptosporidium and Plasmodium (malaria)...
  35. 10TH & 11TH INTERNATIONAL WORKSHOPS ON OPPORTUNISTIC PROTISTS (IWOP-10; IWOP-11)
    EDNA SAYOMI KANESHIRO; Fiscal Year: 2010
    ..The International Workshops on Opportunistic Protists (IWOP) now include research presentations on Cryptosporidium;the microsporidia;Toxoplasma gondii;and free- living amebae turned pathogenic...
  36. Apicomplexan Drug Target Discovery
    Ira J Blader; Fiscal Year: 2013
    ..Toxoplasma gondii, and Cryptosporidium parvum...
  37. MICRONUTRIENTS AND ENTERIC INFECTION IN AFRICAN CHILDREN
    Sherwood Gorbach; Fiscal Year: 2005
    ..HIV-infected and uninfected children living in rural South Africa, with a particular focus on infection with Cryptosporidium parvum and other protozoan pathogens...
  38. MICRONUTRIENTS AND ENTERIC INFECTION IN AFRICAN CHILDREN
    MICHAEL BENNISH; Fiscal Year: 2002
    ..HIV-infected and uninfected children living in rural South Africa, with a particular focus on infection with Cryptosporidium parvum and other protozoan pathogens...
  39. Manipulation of host cell acetylome in AIDS opportunistic infection
    William J Sullivan; Fiscal Year: 2013
    ..intracellular pathogens disrupting acetylation dynamics, our findings promise to have far-reaching impact on other medically relevant infections, including HIV itself and other AIDS opportunist pathogens such as Cryptosporidium.
  40. Mechanisms of Dinitroaniline Action, Selectivity and Resistance
    Naomi S Morrissette; Fiscal Year: 2010
    ..Leishmania spp., Entamoeba spp.,Plasmodium falcipamm, Cryptosporidium parvum and Toxoplasma gondii)...
  41. Evaluation of marketed drugs for rapid development as anti-cryptosporidal agents
    Guan Zhu; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Cryptosporidium parvum is an AIDS-OI pathogen and Category B agent that can cause severe watery diarrhea in humans and animals...
  42. CRYPTOSPORIDIUM DHFR AS A CHEMOTHERAPEUTIC TARGET
    Richard Nelson; Fiscal Year: 1992
    ..will help focus future laboratory and clinical investigations among anti-cryptosporidial agents; if the Cryptosporidium enzyme is exquisitely sensitive to clinically common DHFR-targeted drugs (pyrimethamine, trimethoprim and ..
  43. Multiplex Screening ELISA for Giardia, Cryptosporidium and E. histolytica
    JOEL F HERBEIN; Fiscal Year: 2010
    ..application is a diagnostic screen for the NIAID Biodefense Category B intestinal pathogens Giardia lamblia, Cryptosporidium spp., and Entamoeba histolytica in stool...
  44. Role of Proteases in Cryptosporidium-Host Cell Interactions
    Honorine Ward; Fiscal Year: 2009
    The apicomplexan parasite Cryptosporidium is a significant cause of diarrheal disease worldwide, particularly in immunocompromised hosts such as AIDS patients...
  45. DICATIONIC DRUGS--TREATMENT FOR AIDS-RELATED INFECTIONS
    Richard Tidwell; Fiscal Year: 1999
    ..agents are needed for several other important AIDS related pathogens including: Cryptococcus neoformans, Cryptosporidium parvum, Mycobacterium avium, Toxoplasma gondii, Mycobacterium tuberculosis, and Candida albicans...
  46. Transmission and the respiratory tract in cryptosporidiosis
    Jeffrey Griffiths; Fiscal Year: 2007
    ..studies, human population-based studies, and human volunteer studies), that respiratory infections with Cryptosporidium occur frequently...
  47. LIPOPHILIC ANTIFOLATES AND AIDS OPPORTUNISTIC INFECTIONS
    Andre Rosowsky; Fiscal Year: 2004
    ..of new drugs against Pneumocystis carinii (Pc), Toxoplasma gondii (Tg), Mycobacterium avium (My), and Cryptosporidium parvum (Cp), four opportunistic pathogens known to cause morbidity and mortality in AIDS patients...
  48. Novel activities and the T. gondii vacuolar membrane
    Anthony P Sinai; Fiscal Year: 2012
    ..others have similarly annotated homologs in other less tractable Apicomplexa including Plasmodium and Cryptosporidium spp. suggesting conserved function...
  49. PATHOGENIC/IMMUNOGENIC/STUDIES/CRYPTOSPORIDIUM GENOTYPES
    Abhineet Sheoran; Fiscal Year: 2006
    ..exhibit prominent genotypic and phenotypic differences and consequently, may belong to separate species of Cryptosporidium. While C. parvum types 1 and 2 and C...
  50. DRUG DISCOVERY AGAINST CRYPTOSPORIDIUM PARVUM
    JANET KEITHLY; Fiscal Year: 2003
    DESCRIPTION Cryptosporidium parvum causes one of the opportunistic infections (0I) in AIDS patients for which no treatment is yet known. Although many drugs have been tested against this 0I...
  51. Probiotics for Infectious Diarrhea in Children in South India
    Honorine Ward; Fiscal Year: 2009
    ..Rotavirus and Cryptosporidium spp. are the most important viral and parasitic causes of gastroenteritis in children in south India...
  52. PATHOGENESIS OF INTESTINAL CRYPTOSPORIDIOSIS IN AIDS
    Gerald Keusch; Fiscal Year: 1990
    b>Cryptosporidium parvum is the most common single infectious cause of diarrhea in AIDS patients (AIDS-associated diarrhea)...
  53. 7th International Workshops on Opportunistic Protists
    EDNA KANESHIRO; Fiscal Year: 2001
    ..The focus of these workshops will be on the AIDS-related opportunistic infectious protists, Pneumocystis, Cryptosporidium, Toxoplasma and the microsporidia and amoebae...
  54. Cytoskeletal organization in apicomplexan parasites
    Heide Schatten; Fiscal Year: 2005
    ..parasite Toxoplasma gondii, a model for harmful apicomplexan parasites that include Plasmodium falciparum and Cryptosporidium parvum...
  55. An Ecological Analysis of Cryptosporidium in Kenya
    Jeffrey Griffiths; Fiscal Year: 2004
    ..The WEDDS study is being conducted in Massachusetts, where exposure to Cryptosporidium parvum (CP) is moderate compared to developing world environments...
  56. INTESTINAL CYTOKINES IN CRYPTOSPORIDIOSIS
    A White; Fiscal Year: 2005
    DESCRIPTION (Provided by the applicant): Cryptosporidium parvum is a major cause of diarrhea worldwide, for which there is no reliable antiparasitic therapy. In immunocompetent individuals, C...
  57. DICATIONIC DRUGS--METABOLISM AND TOXICITY
    Richard Tidwell; Fiscal Year: 1993
    ..recently demonstrated activity against two other AIDS-related opportunistic pathogens; Toxoplasma gondii, and Cryptosporidium parvum...
  58. In vitro refinements for Cryptosporidium parvum
    STEVE UPTON; Fiscal Year: 2003
    Over the last decade, our ability to cultivate the intestinal protozoan, Cryptosporidium parvum, in cell culture has increased by >500x...
  59. Molecular Epidemiology of Cryptosporidiosis in India
    Honorine Ward; Fiscal Year: 2007
    ..studies on the functional role of the Cpgp40/15 gene and its glycoprotein products gp40 and gp!5 in mediating Cryptosporidium-host cell interactions to a translational study on Cpgp40/15 polymorphisms in clinical isolates and immune ..
  60. POLYCLONAL ANTIBODY LIBRARIES FOR C PARVUM THERAPY
    Jacqueline Sharon; Fiscal Year: 1999
    ..a safe and effective drug for the treatment or prevention of opportunistic infection with the parasite Cryptosporidium parvum (C. parvum)...
  61. Development of a nucleic acid biosensor for Cryptosporidium Parvum
    GILLIAN VIMBAI KUPAKUWANA; Fiscal Year: 2010
    ..The immediate application is to cryptosporidium, a protozoan that is a common, naturally occurring contaminant of public water supplies...
  62. CONTROL OF CRYPTOSPORIDIOSIS BY NEUTRALIZING ANTIBODIES
    LANCE PERRYMAN; Fiscal Year: 1992
    Cryptosporidiosis is a devastating disease in immunodeficient hosts caused by Cryptosporidium parvum, a sporozoan parasite that replicates in the epithelial cells of the intestinal and/or respiratory tract of man and other mammals...
  63. ANTIADHESIVE RECEPTOR MIMETICS FOR CRYPTOSPORIDIOSIS
    Mark Kuhlenschmidt; Fiscal Year: 2000
    b>Cryptosporidium parvum is a ubiquitous protozoan parasite that causes severe diarrheal disease in both humans and animals. This organism was recently responsible for the largest outbreak of waterborne disease in U. S. history...
  64. PRECLIN EVAL OF THERAPIES FOR CRYPTOSPORIDIUM PARVUM INF
    Saul Tzipori; Fiscal Year: 2000
    ..There is no reliable therapy or preventive agent for cryptosporidium parvum infection, regardless of immune status...