snails

Summary

Summary: Marine, freshwater, or terrestrial mollusks of the class Gastropoda. Most have an enclosing spiral shell, and several genera harbor parasites pathogenic to man.

Top Publications

  1. ncbi Schistosomiasis and water resources development: systematic review, meta-analysis, and estimates of people at risk
    Peter Steinmann
    Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland
    Lancet Infect Dis 6:411-25. 2006
  2. ncbi A strategy to control transmission of Schistosoma japonicum in China
    Long De Wang
    Ministry of Health, Beijing, China
    N Engl J Med 360:121-8. 2009
  3. ncbi Conquering schistosomiasis in China: the long march
    Jurg Utzinger
    Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland
    Acta Trop 96:69-96. 2005
  4. ncbi Phylogeographic history of the land snail Candidula unifasciata (Helicellinae, Stylommatophora): fragmentation, corridor migration, and secondary contact
    Markus Pfenninger
    Abteilung Okologie und Evolution, Zoologisches Institut der J W Goethe Universitat, Frankfurt Main, Germany
    Evolution 56:1776-88. 2002
  5. ncbi Conus venoms: a rich source of novel ion channel-targeted peptides
    Heinrich Terlau
    AG Molekulare und Zelluläre Neuropharmakologie, Max Planck Institut fur experimentelle Medizin, Gottingen, Germany
    Physiol Rev 84:41-68. 2004
  6. ncbi Potential impact of climate change on schistosomiasis transmission in China
    Xiao Nong Zhou
    National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, People s Republic of China
    Am J Trop Med Hyg 78:188-94. 2008
  7. ncbi A potential impact of climate change and water resource development on the transmission of Schistosoma japonicum in China
    G J Yang
    Jiangsu Institute of Parasitic Diseases, Wuxi, Jiangsu, People s Republic of China
    Parassitologia 47:127-34. 2005
  8. ncbi Integrated assessment of heavy metal (Pb, Zn, Cd) highway pollution: bioaccumulation in soil, Graminaceae and land snails
    Bénédicte Viard
    Laboratoire BFE Equipe PEE, Universite de Metz, Campus Bridoux, 2 rue du général Delestraint, 57070 Metz, France
    Chemosphere 55:1349-59. 2004
  9. pmc Schistosomiasis control in China: the impact of a 10-year World Bank Loan Project (1992-2001)
    Chen Xianyi
    Department of Diseases Control, Ministry of Health, Beijing, China
    Bull World Health Organ 83:43-8. 2005
  10. ncbi Identification of novel proteases and immunomodulators in the secretions of schistosome cercariae that facilitate host entry
    Rachel S Curwen
    Department of Biology, University of York, York YO10 5YW, UK
    Mol Cell Proteomics 5:835-44. 2006

Detail Information

Publications328 found, 100 shown here

  1. ncbi Schistosomiasis and water resources development: systematic review, meta-analysis, and estimates of people at risk
    Peter Steinmann
    Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland
    Lancet Infect Dis 6:411-25. 2006
    ....
  2. ncbi A strategy to control transmission of Schistosoma japonicum in China
    Long De Wang
    Ministry of Health, Beijing, China
    N Engl J Med 360:121-8. 2009
    Schistosoma japonicum causes an infection involving humans, livestock, and snails and is a significant cause of morbidity in China.
  3. ncbi Conquering schistosomiasis in China: the long march
    Jurg Utzinger
    Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland
    Acta Trop 96:69-96. 2005
    ..Issuing from the review is a set of recommendations, which might further consolidate current control activities, with the ultimate aim to eliminate schistosomiasis from the Chinese mainland...
  4. ncbi Phylogeographic history of the land snail Candidula unifasciata (Helicellinae, Stylommatophora): fragmentation, corridor migration, and secondary contact
    Markus Pfenninger
    Abteilung Okologie und Evolution, Zoologisches Institut der J W Goethe Universitat, Frankfurt Main, Germany
    Evolution 56:1776-88. 2002
    ..unifasciata differs from general biogeographic patterns of postglacial colonization previously identified for other taxa, and it might represent a common model for species with restricted dispersal...
  5. ncbi Conus venoms: a rich source of novel ion channel-targeted peptides
    Heinrich Terlau
    AG Molekulare und Zelluläre Neuropharmakologie, Max Planck Institut fur experimentelle Medizin, Gottingen, Germany
    Physiol Rev 84:41-68. 2004
    The cone snails (genus Conus) are venomous marine molluscs that use small, structured peptide toxins (conotoxins) for prey capture, defense, and competitor deterrence...
  6. ncbi Potential impact of climate change on schistosomiasis transmission in China
    Xiao Nong Zhou
    National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, People s Republic of China
    Am J Trop Med Hyg 78:188-94. 2008
    ..1% of the surface area of China. Our results call for rigorous monitoring and surveillance of schistosomiasis in a future warmer China...
  7. ncbi A potential impact of climate change and water resource development on the transmission of Schistosoma japonicum in China
    G J Yang
    Jiangsu Institute of Parasitic Diseases, Wuxi, Jiangsu, People s Republic of China
    Parassitologia 47:127-34. 2005
    ..Climate change, coupled with water resource developments in China, may pose additional challenges for the control of schistosomiasis...
  8. ncbi Integrated assessment of heavy metal (Pb, Zn, Cd) highway pollution: bioaccumulation in soil, Graminaceae and land snails
    Bénédicte Viard
    Laboratoire BFE Equipe PEE, Universite de Metz, Campus Bridoux, 2 rue du général Delestraint, 57070 Metz, France
    Chemosphere 55:1349-59. 2004
    ..and autochthonous plants (Graminaceae) gathered at the vicinity of the highway (1-320 m), and in the viscera of snails Helix aspersa, transferred as sentinel in the sites...
  9. pmc Schistosomiasis control in China: the impact of a 10-year World Bank Loan Project (1992-2001)
    Chen Xianyi
    Department of Diseases Control, Ministry of Health, Beijing, China
    Bull World Health Organ 83:43-8. 2005
    ..Chemotherapy was complemented by health education, chemical control of snails and environmental modification where appropriate...
  10. ncbi Identification of novel proteases and immunomodulators in the secretions of schistosome cercariae that facilitate host entry
    Rachel S Curwen
    Department of Biology, University of York, York YO10 5YW, UK
    Mol Cell Proteomics 5:835-44. 2006
    ..All the novel constituents merit investigation as vaccine candidates, and the potential immunomodulators merit investigation as therapeutic agents...
  11. pmc Citizen science reveals unexpected continental-scale evolutionary change in a model organism
    Jonathan Silvertown
    Department of Life Sciences, The Open University, Milton Keynes, United Kingdom
    PLoS ONE 6:e18927. 2011
    ..This may have been because snails adapted to a warming climate through behavioural thermoregulation...
  12. pmc Historical biogeography of the land snail Cornu aspersum: a new scenario inferred from haplotype distribution in the Western Mediterranean basin
    Annie Guiller
    Laboratoire de Parasitologie Pharmaceutique CNRS UMR 6553, Faculte des Sciences Pharmaceutiques et Biologiques, 35043 Rennes, France
    BMC Evol Biol 10:18. 2010
    ..By analysing simultaneously individuals from 73 sites sampled in its putative native range, the present work provides the first broad-scale screening of mitochondrial variation (cyt b and 16S rRNA genes) of C. aspersum...
  13. pmc Sessile snails, dynamic genomes: gene rearrangements within the mitochondrial genome of a family of caenogastropod molluscs
    Timothy A Rawlings
    Cape Breton University, 1250 Grand Lake Road, Sydney, NS B1P 6L2, Canada
    BMC Genomics 11:440. 2010
    ....
  14. pmc Enzootic Angiostrongylus cantonensis in rats and snails after an outbreak of human eosinophilic meningitis, Jamaica
    John F Lindo
    University of the West Indies, Kingston, Jamaica
    Emerg Infect Dis 8:324-6. 2002
    ..in 2000 of eosinophilic meningitis in tourists to Jamaica, we looked for Angiostrongylus cantonensis in rats and snails on the island. Overall, 22% (24/109) of rats harbored adult worms, and 8% (4/48) of snails harbored A...
  15. ncbi Inferring the past to predict the future: climate modelling predictions and phylogeography for the freshwater gastropod Radix balthica (Pulmonata, Basommatophora)
    M Cordellier
    Abteilung Okologie und Evolution, Institut für Ökologie, Evolution und Diversität der Goethe Universität, Siesmayerstrasse 70, 60323 Frankfurt Main, Germany
    Mol Ecol 18:534-44. 2009
    ....
  16. pmc A cluster-randomised intervention trial against Schistosoma japonicum in the Peoples' Republic of China: bovine and human transmission
    Darren J Gray
    Molecular Parasitology Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia
    PLoS ONE 4:e5900. 2009
    ..Preliminary results (1998-2003) of a praziquantel (PZQ)-based pilot intervention study we undertook provided proof of principle that water buffaloes are major reservoir hosts for S. japonicum in the Poyang Lake region, Jiangxi Province...
  17. pmc Schistosomiasis in the People's Republic of China: prospects and challenges for the 21st century
    A G Ross
    Australian Centre for International and Tropical Health and Nutrition, The Queensland Institute of Medical Research, and The University of Queensland, Brisbane, Queensland 4029, Australia
    Clin Microbiol Rev 14:270-95. 2001
    ..In this article, we provide an overview of the biology, epidemiology, clinical features, and prospects for control of oriental schistosomiasis in the People's Republic of China...
  18. ncbi The potential risk and control strategy in low endemic area of schistosomiasis in China
    Zhang Shaoji
    Jiangxi Provincial Institute of Parasitic Diseases, Nanchang 330046, People s Republic of China
    Acta Trop 82:289-93. 2002
    ..to describe and analyze the potential risk and suggest the corresponding control strategy in low endemic of schistosomiasis in China...
  19. ncbi Identifying high-risk areas of schistosomiasis and associated risk factors in the Poyang Lake region, China
    W X Peng
    Department of Epidemiology, School of Public Health, Fudan University, 138 Yixueyuan Road, Shanghai 200032, People s Republic of China
    Parasitology 137:1099-107. 2010
    ..Such information can be used to plan locally targeted interventions based on anthelminthic drug administration, snail control and sanitation improvement...
  20. ncbi Inference of a radiation in Mastus (Gastropoda, Pulmonata, Enidae) on the island of Crete
    Aris Parmakelis
    Natural History Museum of Crete and Department of Biology, University of Crete, P O Box 2208, Irakleio, 71409, Greece
    Evolution 59:991-1005. 2005
    ..Overall, our results favoured a nonecological radiation scenario in the Cretan Mastus species due to an allopatric divergence of secondary sexual characters...
  21. ncbi Turning snails into slugs: induced body plan changes and formation of an internal shell
    Raphaela Osterauer
    Animal Physiological Ecology Department, Institute of Evolution and Ecology, University of Tubingen, D 72072 Tubingen, Germany
    Evol Dev 12:474-83. 2010
    ..That is, the anus of the treated snails is located anteriorly, but the gill and the designated mantle tissue remains in a posterior location, thus ..
  22. pmc Effect of an integrated control strategy for schistosomiasis japonica in the lower reaches of the Yangtze River, China: an evaluation from 2005 to 2008
    Le Ping Sun
    Jiangsu Institute of Parasitic Diseases, 117 Yangxiang, Meiyuan, Wuxi 214064, Jiangsu Province, People s Republic of China
    Parasit Vectors 4:243. 2011
    ..There are many interventions implemented to control the transmission of the disease. The purpose of the present study was to investigate the effects of an integrated control strategy for schistosomiasis control...
  23. ncbi The maintenance of sex, clonal dynamics, and host-parasite coevolution in a mixed population of sexual and asexual snails
    Jukka Jokela
    1EAWAG, Swiss Federal Institute of Aquatic Science and Technology, Uberlandstrasse 133, 8600 Dubendorf, Switzerland
    Am Nat 174:S43-53. 2009
    ..Here, we report on long-term dynamics and parasite coevolution in a "mixed" (sexual and asexual) population of snails (Potamopyrgus antipodarum)...
  24. pmc Detection of Schistosoma mansoni and Schistosoma haematobium DNA by loop-mediated isothermal amplification: identification of infected snails from early prepatency
    Ibrahim Abbasi
    Hebrew University, Hadassah Medical School, Jerusalem, Israel
    Am J Trop Med Hyg 83:427-32. 2010
    ..Molecular monitoring of prepatent schistosome infection in snails by the polymerase chain reaction (PCR) has been used for studying human-to-snail transmission, and snail prepatent ..
  25. pmc Trematode parasites infect or die in snail hosts
    Kayla C King
    Department of Biology, Indiana University, Bloomington, IN 47405, USA
    Biol Lett 7:265-8. 2011
    ..Our results show that parasites do not get a second chance: they either infect or are killed by the host. The results suggest strong selection against parasites that are not adapted to local host genotypes...
  26. pmc Macroevolution of venom apparatus innovations in auger snails (Gastropoda; Conoidea; Terebridae)
    M Castelin
    Hunter College, The City University of New York, NY, NY 10065, USA
    Mol Phylogenet Evol 64:21-44. 2012
    ....
  27. ncbi How flexible is phenotypic plasticity? Developmental windows for trait induction and reversal
    Jason T Hoverman
    Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    Ecology 88:693-705. 2007
    ..We exposed freshwater snails (Helisoma trivolvis) to environments in which predatory water bugs (Belostoma flumineum) were always absent, ..
  28. pmc The functional expression and characterisation of a cysteine peptidase from the invasive stage of the neuropathogenic schistosome Trichobilharzia regenti
    Katerina Dolecková
    Department of Parasitology, Faculty of Science, Charles University in Prague, Vinicna 7, 12844 Prague 2, Czech Republic
    Int J Parasitol 39:201-11. 2009
    ..mansoni and Schistosoma haematobium but not found in Schistosoma japonicum or in bird schistosomes...
  29. ncbi Impact of changing water levels and weather on Oncomelania hupensis hupensis populations, the snail host of Schistosoma japonicum, downstream of the Three Gorges Dam
    Edmund Y W Seto
    School of Public Health, University of California, Berkeley, CA 94720, USA
    Ecohealth 5:149-58. 2008
    ..However, additional data are needed to determine whether snail populations that are typically destroyed by seasonal floods may live longer in more stable environments created by the dam...
  30. ncbi Achievements of schistosomiasis control in China
    Hongchang Yuan
    Department of Epidemiology, School of Public Health, Fudan University, Shanghai, China
    Mem Inst Oswaldo Cruz 97:187-9. 2002
    ..Successfully controlling schistosomiasis in China is still a long-term task but will be achieved without doubt along with the economic development and the promotion of living and cultural standard of people...
  31. ncbi Effect of floods on the transmission of schistosomiasis in the Yangtze River valley, People's Republic of China
    Xiao Hua Wu
    National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, People s Republic of China
    Parasitol Int 57:271-6. 2008
    ..data, covering a 22-year period, were carried out to elucidate the dispersal patterns of intermediate host snails (Oncomelania hupensis), and acute and chronic infections with Schistosoma japonicum in humans in relation to ..
  32. pmc Historical invasions of the intertidal zone of Atlantic North America associated with distinctive patterns of trade and emigration
    Susan H Brawley
    School of Marine Sciences, University of Maine, Orono, ME 04469, USA
    Proc Natl Acad Sci U S A 106:8239-44. 2009
    ..littorea, using cytochrome b haplotypes. Eight of the 9 Pictou haplotypes were found in snails collected from Ireland and Scotland...
  33. pmc Review. Sympatric, parapatric or allopatric: the most important way to classify speciation?
    Roger K Butlin
    Department of Animal and Plant Sciences, University of Sheffield, Western Bank, Sheffield S10 2TN, UK
    Philos Trans R Soc Lond B Biol Sci 363:2997-3007. 2008
    ..We suggest that it is more productive to study the current balance between local adaptation and gene flow, the interaction between components of reproductive isolation and the genetic basis of differentiation...
  34. ncbi Biogeography: molecular trails from hitch-hiking snails
    Edmund Gittenberger
    National Museum of Natural History Naturalis, PO Box 9517, 2300 RA Leiden, The Netherlands
    Nature 439:409. 2006
    Darwin was fascinated by the transportation of land snails across great swathes of open ocean by birds--he even immersed snails in sea water to see how long they would survive...
  35. ncbi Fasciola hepatica: identification of molecular markers for resistant and susceptible Pseudosuccinea columella snail hosts
    Alfredo Gutierrez
    Laboratorio de Malacologia, Instituto Pedro Kouri, IPK Apartado 601, Marianao 13, Ciudad Habana, Cuba
    Exp Parasitol 105:211-8. 2003
    ..and nuclear rDNA ITS sequencing were performed to search for genetic differences between Pseudosuccinea columella snails susceptible and resistant to Fasciola hepatica infection...
  36. pmc Distinct genetic diversity of Oncomelania hupensis, intermediate host of Schistosoma japonicum in mainland China as revealed by ITS sequences
    Qin Ping Zhao
    Department of Parasitology, School of Basic Medical Science, Wuhan University, Wuhan, Hubei Province, China
    PLoS Negl Trop Dis 4:e611. 2010
    ..O. hupensis largely determines the parasite's geographical range. How O. hupensis's genetic diversity is distributed geographically in mainland China has never been well examined with DNA sequence data...
  37. pmc Nodal signalling is involved in left-right asymmetry in snails
    Cristina Grande
    Department of Molecular and Cell Biology, University of California, Berkeley, California 94720 3200, USA
    Nature 457:1007-11. 2009
    ..in the other two main clades of Bilateria: Ecdysozoa (including flies and nematodes) and Lophotrochozoa (including snails and annelids). Here we report the first evidence for a nodal orthologue in a non-deuterostome group...
  38. ncbi Landscape genetics: the correlation of spatial and genetic distances of Oncomelania hupensis, the intermediate host snail of Schistosoma japonicum in mainland China
    Shi Zhu Li
    National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, 200025, China
    Geospat Health 3:221-31. 2009
    ..Thirteen populations of O. hupensis snails, representing four types of ecological settings, were collected to compare genetic and spatial distances...
  39. ncbi The complete mitochondrial genome of Radix balthica (Pulmonata, Basommatophora), obtained by low coverage shot gun next generation sequencing
    B Feldmeyer
    Biodiversity and Climate Research Center BiK F, Siesmayerstr 70A, 60323 Frankfurt am Main, Germany
    Mol Phylogenet Evol 57:1329-33. 2010
    ..Next generation sequencing proved to be a fast and easy method for sequencing an entire mitochondrial genome...
  40. ncbi Postglacial recolonization at a snail's pace (Trochulus villosus): confronting competing refugia hypotheses using model selection
    A Dépraz
    Department of Ecology and Evolution, Biophore Quartier Sorge, University of Lausanne, CH 1015 Lausanne, Switzerland
    Mol Ecol 17:2449-62. 2008
    ..villosus populations. Provided that fine-scale sampling designs and various analytical approaches are combined, it is possible to refine our necessary understanding of species responses to environmental changes...
  41. ncbi Solving cryptogenic histories using host and parasite molecular genetics: the resolution of Littorina littorea's North American origin
    April M H Blakeslee
    Department of Zoology, University of New Hampshire, 46 College Road, Durham, NH 03824, USA
    Mol Ecol 17:3684-96. 2008
    ..Our study therefore resolves not only a specific cryptogenic history, but it also demonstrates the success of our approach generally and could be used in resolving difficult invasion histories worldwide...
  42. ncbi A geographic information and remote sensing based model for prediction of Oncomelania hupensis habitats in the Poyang Lake area, China
    Jia gang Guo
    National Institute of Parasitic Disease, Chinese Center for Diseases Control and Preventive, Shanghai 200025, China
    Acta Trop 96:213-22. 2005
    ..0-8.5 were derived from existing records. Both climatic features represent suitable breeding conditions for the snails. Preliminary validation of the model at 10 sites around Poyang Lake revealed an excellent accuracy for predicting ..
  43. pmc Neogastropod phylogenetic relationships based on entire mitochondrial genomes
    Regina L Cunha
    Departamento de Biodiversidad y Biologia Evolutiva, Museo Nacional de Ciencias Naturales CSIC, 28006 Madrid, Spain
    BMC Evol Biol 9:210. 2009
    The Neogastropoda is a highly diversified group of predatory marine snails (Gastropoda: Caenogastropoda)...
  44. pmc New perspectives on host-parasite interplay by comparative transcriptomic and proteomic analyses of Schistosoma japonicum
    Feng Liu
    Chinese National Human Genome Center, Shanghai, China
    PLoS Pathog 2:e29. 2006
    ....
  45. ncbi The Pleistocene glaciations and the evolutionary history of the polytypic snail species Arianta arbustorum (Gastropoda, Pulmonata, Helicidae)
    E Gittenberger
    Nationaal Natuurhistorisch Museum, P O Box 9517, NL 2300 RA Leiden, The Netherlands
    Mol Phylogenet Evol 30:64-73. 2004
    ..We analysed a portion of the mitochondrial gene cytochrome oxidase I for 100 snails of the species A...
  46. pmc A species delimitation approach in the Trochulus sericeus/hispidus complex reveals two cryptic species within a sharp contact zone
    Aline Dépraz
    Lab Centre, Biodiversity and Climate Research Centre, BioCampus Siesmayerstrasse, D 60054 Frankfurt am Main, Germany
    BMC Evol Biol 9:171. 2009
    ..We investigated the species boundaries of two cryptic lineages of the land snail genus Trochulus in a contact zone, using mitochondrial and nuclear DNA marker as well as shell morphometrics...
  47. ncbi Remote sensing for predicting potential habitats of Oncomelania hupensis in Hongze, Baima and Gaoyou lakes in Jiangsu province, China
    Guo Jing Yang
    Jiangsu Institute of Parasitic Diseases, Wuxi 214064, People s Republic of China
    Geospat Health 1:85-92. 2006
    ..The generated risk map can be used by health policy makers to guide mitigation policies targetting the possible spread of O. hupensis, and with the aim of containing the transmission of S. japonicum...
  48. ncbi Complete sequence of the mitochondrial DNA of the primitive opisthobranch gastropod Pupa strigosa: systematic implication of the genome organization
    A Kurabayashi
    Institute of Biological Sciences, University of Tsukuba, Japan
    Mol Biol Evol 17:266-77. 2000
    ..The Pupa mitochondrial genome is highly compact and shows the following unusual features, like pulmonate land snails: (1) extremely small genome size, (2) absence of lengthy noncoding regions (with the largest intergenic spacer ..
  49. ncbi Three Gorges Dam and its impact on the potential transmission of schistosomiasis in regions along the Yangtze River
    Huai Min Zhu
    Department of Etiologic Biology, Second Military Medical University, Shanghai 200433, China
    Ecohealth 5:137-48. 2008
    ..These changes, however, carry ambivalent implications for the reproduction of Oncomelania snails and the spreading of schistosome infections...
  50. ncbi Nonparametric spatial analysis to detect high-risk regions for schistosomiasis in Guichi, China
    Zhijie Zhang
    Department of Epidemiology, School of Public Health, Fudan University, Shanghai 200032, People s Republic of China
    Trans R Soc Trop Med Hyg 103:1045-52. 2009
    ..In addition, the commonly used epidemiological indices, RR and ER, are examined and emphasized from the spatial point of view, which will be helpful for exploring many other epidemiological indices...
  51. pmc Evaluation of mammalian and intermediate host surveillance methods for detecting schistosomiasis reemergence in southwest China
    Elizabeth J Carlton
    Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, California, USA
    PLoS Negl Trop Dis 5:e987. 2011
    ..Schistosomiasis has reemerged in China, threatening schistosomiasis elimination efforts. Surveillance methods that can identify locations where schistosomiasis has reemerged are needed to prevent the further spread of infections...
  52. pmc Echinostoma revolutum: metacercariae in Filopaludina snails from Nam Dinh Province, Vietnam, and adults from experimental hamsters
    Jong Yil Chai
    Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine, Seoul 110 799, Korea
    Korean J Parasitol 49:449-55. 2011
    We detected metacercariae of Echinostoma revolutum in Filopaludina sp. snails purchased from a local market in Nam Dinh Province for the first time in Vietnam...
  53. ncbi Remote sensing and spatial statistical analysis to predict the distribution of Oncomelania hupensis in the marshlands of China
    Zhi Ying Zhang
    Department of Epidemiology, Fourth Military Medical University, Shaanxi Province 710032, and National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, China
    Acta Trop 96:205-12. 2005
    ..Although stepwise regression demonstrated that O. hupensis densities of live snails in the marshlands related significantly to the modified soil-adjusted vegetation index, wetness and land surface ..
  54. pmc Accelerated mutation accumulation in asexual lineages of a freshwater snail
    Maurine Neiman
    Department of Biology, Roy J Carver Center for Comparative Genomics, University of Iowa, Iowa, USA
    Mol Biol Evol 27:954-63. 2010
    ....
  55. pmc Reconstructing the evolutionary history of the radiation of the land snail genus Xerocrassa on Crete based on mitochondrial sequences and AFLP markers
    Jan Sauer
    Zoological Museum, University of Hamburg, Martin Luther King Platz 3, 20146 Hamburg, Germany
    BMC Evol Biol 10:299. 2010
    ..To distinguish between the reasons for the nonmonophyly of several species in the mitochondrial gene tree we analysed nuclear AFLP markers...
  56. ncbi A geographic mosaic of passive dispersal: population structure in the endemic Hawaiian amber snail Succinea caduca (Mighels, 1845)
    Brenden S Holland
    Center for Conservation Research and Training, Pacific Biosciences Research Center, University of Hawaii, Honolulu, Hawaii 96822, USA
    Mol Ecol 16:2422-35. 2007
    ....
  57. ncbi Molecular phylogeny and historical biogeography of the land snail genus Solatopupa (Pulmonata) in the peri-Tyrrhenian area
    Valerio Ketmaier
    Unit of Evolutionary Biology Systematic Zoology, Institute of Biochemistry and Biology, University of Potsdam, Karl Liebknecht Str 24 25, D 14476 Potsdam, Germany
    Mol Phylogenet Evol 39:439-51. 2006
    ..Because the potential for dispersal of these snails is low, the insular range of this species has been traditionally related to the Oligocenic detachment of the ..
  58. ncbi Arresting mantle formation and redirecting embryonic shell gland tissue by platinum2+ leads to body plan modifications in Marisa cornuarietis (Gastropoda, Ampullariidae)
    Leonie Marschner
    Animal Physiological Ecology, Institute of Evolution and Ecology, Biology Department, University of Tubingen, Tübingen D 72072, Germany
    J Morphol 273:830-41. 2012
    ..In 2010, our group reported that high Pt concentrations cause body plan alterations in snails and prevent the formation of an external shell during M. cornuarietis embryogenesis...
  59. ncbi The development and evolution of left-right asymmetry in invertebrates: lessons from Drosophila and snails
    Takashi Okumura
    Department of Biological Science and Technology, Tokyo University of Science, Noda, Japan
    Dev Dyn 237:3497-515. 2008
    ..review of currently available information illuminates the prospective value of Drosophila and pulmonate snails for innovative new research aimed at elucidating these mechanisms...
  60. ncbi Isolation and characterization of cultivable fermentative bacteria from the intestine of two edible snails, Helixpomatia and Cornu aspersum (Gastropoda: Pulmonata)
    Maryvonne Charrier
    Unite de Microbiologie, CR INRA de Clermont Ferrand Theix, Saint Genes Champanelle, F 63122, France
    Biol Res 39:669-81. 2006
    The intestinal microbiota of the edible snails Cornu aspersum fSyn: H. aspersa), and Helix pomatia were investigated by culture-based methods, 16S rRNA sequence analyses and phenotypic characterisations...
  61. ncbi The ecology of the Bithynia first intermediate hosts of Opisthorchis viverrini
    Trevor Petney
    Department of Ecology and Parasitology, Karlsruhe Institute of Technology, Kornblumenstrasse 13, Karlsruhe, Germany
    Parasitol Int 61:38-45. 2012
    ..We show not only that detailed ecological studies are required to clarify the epidemiology of opisthorchiasis, but also that the taxonomic status of the Bithynia species transmitting O. viverrini requires clarification...
  62. pmc Gut bacterial communities in the giant land snail Achatina fulica and their modification by sugarcane-based diet
    Alexander M Cardoso
    Instituto Nacional de Metrologia, Qualidade e Tecnologia, Rio de Janeiro, Brazil
    PLoS ONE 7:e33440. 2012
    ..for the first time the complexity of bacterial communities occurring in the digestive tracts of field-collected snails (FC) by using culture-independent molecular analysis...
  63. ncbi Surveillance for schistosomiasis japonica in China from 2000 to 2003
    Gen Ming Zhao
    Department of Epidemiology, School of Public Health, Fudan University, Shanghai 200023, China
    Acta Trop 96:288-95. 2005
    ..Significant reductions of densities of living intermediate host snails and infected snails were noted in only two sites...
  64. ncbi Internal selection against the evolution of left-right reversal
    Hiroki Utsuno
    Department of Biology, Shinshu University, Matsumoto 390 8621, Japan
    Evolution 65:2399-411. 2011
    ..exploiting hermaphroditism and the maternal inheritance of left-right polarity, we generated dextral and sinistral snails that share the same zygotic genotype...
  65. pmc The role of the proteinase inhibitor ovorubin in apple snail eggs resembles plant embryo defense against predation
    Marcos Sebastián Dreon
    Instituto de Investigaciones Bioquímicas de La Plata INIBIOLP, CONICET Universidad Nacional de La Plata, La Plata, Argentina
    PLoS ONE 5:e15059. 2010
    ..Through biochemical, biophysical and feeding experiments we studied the proteinase inhibitor function of ovorubin in egg defenses...
  66. ncbi Islands within an island: phylogeography and conservation genetics of the endangered Hawaiian tree snail Achatinella mustelina
    Brenden S Holland
    Kewalo Marine Laboratory, Pacific Biomedical Research Center, University of Hawaii, 41 Ahui Street, Honolulu, HI 96813, USA
    Mol Ecol 11:365-75. 2002
    ..Limited data sets for two additional endangered Hawaiian tree snails, A. livida and A. sowerbyana, were also developed for comparative purposes...
  67. ncbi Optimization of metacercarial production for three digenean species by the use of petri dishes for raising lettuce-fed Galba truncatula
    D Rondelaud
    UPRES EA no 3174 USC INRA, Faculties of Medicine and Pharmacy, 87025, Limoges Cedex, France
    Parasitol Res 100:861-5. 2007
    ..daubneyi were carried out at 20 degrees C to determine if the use of 14-cm petri dishes for breeding lettuce-fed snails enhanced the characteristics of snail infections...
  68. ncbi Distribution of freshwater snails in family-based VAC ponds and associated waterbodies with special reference to intermediate hosts of fish-borne zoonotic trematodes in Nam Dinh Province, Vietnam
    Bui Thi Dung
    Department of Parasitology, Institute of Ecology and Biological Resources, Vietnamese Academy of Science and Technology, 18 Hoang Quoc Viet, Nghia Do, Cau Giay, Ha Noi, Viet Nam
    Acta Trop 116:15-23. 2010
    ..This paper describes the distribution of freshwater snails and occurrence of trematode infections in these in VAC ponds and associated habitats as part of a major study on ..
  69. ncbi The public health significance and control of schistosomiasis in China--then and now
    Xiao Nong Zhou
    National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai 200025, China
    Acta Trop 96:97-105. 2005
    ..Finally, we discuss remaining challenges for schistosomiasis control with the ultimate goal of disease elimination...
  70. ncbi Juvenile Lymnaea ventilate, learn and remember differently than do adult Lymnaea
    Chloe McComb
    Calgary Brain Institute, Department of Physiology and Biophysics, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada
    J Exp Biol 208:1459-67. 2005
    Adult snails are capable of learning associatively not to perform aerial respiration and then to consolidate the acquired behaviour into long-term memory (LTM)...
  71. ncbi Planorbidae, lymnaeidae and physidae of Peru (Mollusca: Basommatophora)
    W Lobato Paraense
    Departamento de Malacologia, Instituto Oswaldo Cruz FIOCRUZ, 21045 900 Rio de Janeiro, RJ, Brasil
    Mem Inst Oswaldo Cruz 98:767-71. 2003
    ..tenagophila (Orbigny, 1835), Helisoma trivolvis (Say, 1817), H. duryi (Wetherby, 1879), Physa acuta Draparnaud, 1801, and seemingly P. peruviana Gray, 1828. B. pucaraensis is considered a junior synonym of B. peregrina (Orbigny, 1835)...
  72. pmc Schistosomiasis
    F Lewis
    Biomedical Research Institute, Rockville, Maryland, USA
    Curr Protoc Immunol . 2001
    ..is given of the basic steps that are important in maintaining the snail intermediate host, and infecting the snails with schistosome miracidia...
  73. ncbi Impairment of long-term associative memory in aging snails (Lymnaea stagnalis)
    Petra M Hermann
    Department of Biological Sciences, Faculty of Science, University of Calgary, Alberta, Canada
    Behav Neurosci 121:1400-14. 2007
    ..Together, these results present the Lymnaea feeding system as a powerful paradigm for investigations of cellular and molecular foundations of biological aging in the brain...
  74. ncbi Comparative study on the susceptibility of freshwater species to copper-based pesticides
    Eduardo Cyrino de Oliveira-Filho
    Embrapa Cerrados, Rodovia BR020, Km 18, Planaltina, DF CEP 73301 970, Brazil
    Chemosphere 56:369-74. 2004
    ..1; hardness 44 +/- 1 mg/l as CaCO3; DO 8-9 mg/l at the beginning and > 4 mg/l at the end; temperature, fish and snails 25 +/- 1 degrees C, Daphnia 20 +/- 2 degrees C, algae 24 +/- 1 degrees C. D...
  75. ncbi Impact of the South-to-North Water Diversion Project on the transmission of Schistosoma japonicum in China
    W Wang
    Jiangsu Institute of Parasitic Diseases, Meiyuan, Yangxiang 117, Wuxi 214064, Jiangsu Province, China
    Ann Trop Med Parasitol 103:17-29. 2009
    ..Except over the first 6 months in Xuzhou, the snails moved north of their natural distribution did not survive and reproduce as well as those in Zhenjiang, and all ..
  76. ncbi G-proteins modulate invertebrate synaptic calcium channel (LCav2) differently from the classical voltage-dependent regulation of mammalian Cav2.1 and Cav2.2 channels
    Xuan Huang
    Department of Biology, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada
    J Exp Biol 213:2094-103. 2010
    ....
  77. ncbi First proteome of the egg perivitelline fluid of a freshwater gastropod with aerial oviposition
    Jin Sun
    Department of Biology, Hong Kong Baptist University, Hong Kong, China
    J Proteome Res 11:4240-8. 2012
    ..Characterization of the PVF proteome has opened the gate for further studies aiming to understand the evolution of the novel proteins and their contribution to the switch to aerial oviposition...
  78. ncbi Spatial and temporal population genetic structure of four northeastern Pacific littorinid gastropods: the effect of mode of larval development on variation at one mitochondrial and two nuclear DNA markers
    Hyuk Je Lee
    Department of Integrative Biology, University of Guelph, ON, Canada
    Mol Ecol 18:2165-84. 2009
    ..b>Snails were collected from the same three sites on the west coast of Vancouver Island, Canada in 1997 and again in 2007...
  79. ncbi The detection of snail host habitats in liver fluke infected farms by use of plant indicators
    Daniel Rondelaud
    UPRES EA 3174, Faculty of Pharmacy, 87025 Limoges, France
    Vet Parasitol 181:166-73. 2011
    ..The positive sites may be detected using a two-step method including first categorization of hydrographical zones and then, within a zone, use of one or several indicator plants (frequently J. acutiflorus)...
  80. ncbi High within-population mitochondrial DNA variation due to microvicariance and population mixing in the land snail Euhadra quaesita (Pulmonata: Bradybaenidae)
    Y Watanabe
    Biological Institute, Graduate School of Science, Tohoku University, Aobayama, Sendai, Japan
    Mol Ecol 10:2635-45. 2001
    ..This repetition of isolation and mixing has resulted in an exceptionally fine scale of geographical variation, and the accumulation of high genetic diversity within and between populations of this species...
  81. pmc Predator-induced morphological plasticity across local populations of a freshwater snail
    Christer Brönmark
    Aquatic Ecology Unit, Department of Biology, University of Lund, Lund, Sweden
    PLoS ONE 6:e21773. 2011
    ..Shell shape was quantified in snails from geographically separated pond populations with and without molluscivorous fish...
  82. ncbi Exposure routes of copper: short term effects on survival, weight, and uptake in Florida apple snails (Pomacea paludosa)
    Tham C Hoang
    Florida International University, Ecotoxicology and Risk Assessment Laboratory, Department of Environmental Studies, Southeast Environmental Research Center, 3000 NE 151st Street, North Miami, FL 33181, USA
    Chemosphere 76:407-14. 2009
    The uptake and effects (survival, weight) of copper (Cu) on Florida apple snails (Pomacea paludosa) via exposures to copper-enriched agricultural soil-water and water-only treatments were investigated...
  83. ncbi Human sewage identified as likely source of white pox disease of the threatened Caribbean elkhorn coral, Acropora palmata
    Kathryn Patterson Sutherland
    Department of Biology, Rollins College, Winter Park, FL 32789, USA
    Environ Microbiol 12:1122-31. 2010
    ..This strain (PDR60) was also identified from corallivorious snails (Coralliophila abbreviata), reef water, and two non-acroporid coral species, Siderastrea siderea and Solenastrea ..
  84. ncbi Angiostrongylus cantonensis: effect of combination therapy with albendazole and dexamethasone on Th cytokine gene expression in PBMC from patients with eosinophilic meningitis
    Zongli Diao
    Beijing Tropical Medicine Research Institute, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
    Exp Parasitol 123:1-5. 2009
    ..Combination therapy with albendazole and dexamethasone can shift the cytokine responses from Th2 to Th1 dominance, which may be a therapeutic mechanism...
  85. ncbi Rapid recovery of genetic diversity of dogwhelk (Nucella lapillus L.) populations after local extinction and recolonization contradicts predictions from life-history characteristics
    I Colson
    School of Biological Sciences, University of Wales, Bangor, Deiniol Road, Bangor, Gwynedd LL57 2UW, UK
    Mol Ecol 13:2223-33. 2004
    ..Our results also stress the importance of local factors (geographical or ecological) in determining genetic structure of dogwhelk populations...
  86. ncbi Light, nutrients, and herbivore growth in oligotrophic streams
    Walter R Hill
    Environmental Sciences Division, Oak Ridge National Laboratory, P O Box 2008, Oak Ridge, Tennessee 37830 6351, USA
    Ecology 91:518-27. 2010
    ..Periphyton nitrogen and phosphorus concentrations were much lower than the concentrations of these elements in snails, and they bottomed out in early spring when streambed irradiances were highest...
  87. ncbi A novel molluscicidal formulation of niclosamide
    Jian Rong Dai
    Jiangsu Institute of Parasitic Diseases, Wuxi, 214064, People s Republic of China
    Parasitol Res 103:405-12. 2008
    ..SCN showed better molluscicidal effects than conventional formulation of WPN, as determined by LC(50) for adult snails, young snails, and snail eggs. The acute toxicity of SCN to Brachdanio rerio hamiton was less than WPN...
  88. ncbi Insights into the relationships of Palearctic and Nearctic lymnaeids (Mollusca: Gastropoda) by rDNA ITS-2 sequencing and phylogeny of stagnicoline intermediate host species of Fasciola hepatica
    M D Bargues
    Departamento de Parasitologia, Facultad de Farmacia, Universidad de Valencia, Av Vicent Andres Estelles s n, 46100 Burjassot, Valencia, Spain
    Parasite 10:243-55. 2003
    ..own capacities together with the adaptation and colonization abilities of its specific vector hosts, freshwater snails of the family Lymnaeidae...
  89. pmc Multiple near-identical genotypes of Schistosoma japonicum can occur in snails and have implications for population-genetic analyses
    Mingbo Yin
    National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, 207 Rui Jin Rd II, Shanghai 200025, PR China
    Int J Parasitol 38:1681-91. 2008
    ..adult Schistosoma japonicum raised in rabbits exposed to pooled cercariae from small numbers of naturally infected snails from several localities in China. As expected, duplicate multi-locus genotypes (MLGs) were found among these worms...
  90. pmc Model approaches for estimating the influence of time-varying socio-environmental factors on macroparasite transmission in two endemic regions
    Justin Remais
    Department of Environmental Health, Rollins School of Public Health, Emory University, 1518 Clifton Rd NE, Atlanta, GA 30322, USA
    Epidemics 1:213-20. 2009
    ..The importance of these factors for control programs and surveillance is discussed...
  91. ncbi Evolutionary aspects of population structure for molecular and quantitative traits in the freshwater snail Radix balthica
    G Evanno
    Department of Ecology and Evolution, University of Lausanne, Lausanne, Switzerland
    J Evol Biol 19:1071-82. 2006
    ..Our results suggest that in this floodplain habitat, local adaptation of R. balthica populations may be hindered by genetic drift, and possibly altered by uneven gene flow linked to flood frequency...
  92. ncbi Surveillance of schistosomiasis in five provinces of China which have reached the national criteria for elimination of the disease
    Xiao Hua Wu
    National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai 200025, China
    Acta Trop 96:276-81. 2005
    ..infected persons were discovered in Guangdong, residual snail habitats including Schistosoma japonicum-infected snails were found in the neighbourhood...
  93. ncbi Partial selfing, ecological disturbance and reproductive assurance in an invasive freshwater snail
    P Y Henry
    Centre d Ecologie Fonctionnelle et Evolutive, CNRS, 1919 Route de Mende, F 34293 Montpellier cedex 5, France
    Heredity (Edinb) 95:428-36. 2005
    ..acuta, as well as alternative theories explaining the occurrence of partial selfing, as either a genetically fixed or plastic trait...
  94. ncbi Metapopulation dynamics and biological invasions: a spatially explicit model applied to a freshwater snail
    Benoit Facon
    Department of Ecology and Evolution, Biology Building, University of Lausanne, 1015 Lausanne, Switzerland
    Am Nat 168:769-83. 2006
    ..Finally, we discuss the benefits of this approach for the understanding of invasions in fragmented landscapes...
  95. pmc Quantitative detection of Schistosoma japonicum cercariae in water by real-time PCR
    Yuen Wai Hung
    Center for Occupational and Environmental Health, School of Public Health, University of California, Berkeley, California, USA
    PLoS Negl Trop Dis 2:e337. 2008
    ..Overall, the method has the potential to be applied to environmental water samples to produce a rapid, reliable assay for cercarial location in endemic areas...
  96. ncbi The A-superfamily of conotoxins: structural and functional divergence
    Ameurfina D Santos
    Department of Biology, University of Utah, Salt Lake City, Utah 84112, USA
    J Biol Chem 279:17596-606. 2004
    ..In this report, we define the A-conotoxin superfamily, which is widely expressed in venoms of the predatory cone snails (Conus), and show how gene products that diverge considerably in structure and function have arisen within the ..
  97. ncbi Ecosystem energetic implications of parasite and free-living biomass in three estuaries
    Armand M Kuris
    Department of Ecology, Evolution and Marine Biology and Marine Science Institute, University of California, Santa Barbara, California 93106, USA
    Nature 454:515-8. 2008
    ..This biomass and productivity of parasites implies a profound role for infectious processes in these estuaries...
  98. ncbi Cue reliability, risk sensitivity and inducible morphological defense in a marine snail
    Paul E Bourdeau
    Department of Ecology and Evolution, Stony Brook University, Stony Brook, NY 11794 5245, USA
    Oecologia 162:987-94. 2010
    ..b>Snails were exposed to chemical risk cues from a factorial combination of damaged prey presented in isolation or consumed ..
  99. pmc Developmental gene expression profiles of the human pathogen Schistosoma japonicum
    Geoffrey N Gobert
    Division of Infectious Diseases and Immunology, Queensland Institute of Medical Research, Brisbane, Queensland, Australia
    BMC Genomics 10:128. 2009
    ..Advanced analyses including ANOVA, principal component analysis, and hierarchal clustering provided a global synopsis of gene expression relationships among the different developmental stages of the schistosome parasite...
  100. pmc A cluster-randomized bovine intervention trial against Schistosoma japonicum in the People's Republic of China: design and baseline results
    Darren J Gray
    Australian Centre for International and Tropical Health and Nutrition, The University of Queensland and The Queensland Institute of Medical Research, Brisbane, Queensland, Australia
    Am J Trop Med Hyg 77:866-74. 2007
    ..japonicum. The combination of such a vaccine with other control strategies could potentially eliminate S. japonicum from southern China...
  101. ncbi First record of molluscs naturally infected with Angiostrongylus cantonensis (Chen, 1935) (Nematoda: Metastrongylidae) in Brazil
    Roberta Lima Caldeira
    Laboratório de Helmintoses Intestinais, Instituto René Rachou, FIOCRUZ, Belo Horizonte, MG, 30190 002, Brazil
    Mem Inst Oswaldo Cruz 102:887-9. 2007
    ..The snails were identified as Sarasinula marginata (45 specimens), Subulina octona (157), Achatina fulica (45) and Bradybaena ..

Research Grants68

  1. Blood Coagulation Protein - Metal Ion - Lipid Interactions
    Francis J Castellino; Fiscal Year: 2013
    ..Vitamin K-dependent gamma-carboxyglutamate (Gla)- containing natural peptides from cone snails represent a potentially significant therapeutic class of NMDAR inhibitors that are allosteric to the ion channel ..
  2. Chemical Biodiversity: Investigating the Phylogeny and Functional Toxins of Venom
    MANDE N HOLFORD; Fiscal Year: 2010
    ..for investigating cellular communication in the central nervous system are the toxins from venomous marine snails. Cone snails (Conidae;Linnaeus, 1758), auger snails or terebrids (Terebridae;Morch, 1852), and turrids (Turridae;..
  3. IMMUNOBIOLOGY OF SCHISTOSOME-MOLLUSC INTERACTIONS
    Timothy P Yoshino; Fiscal Year: 2013
    ..for completing their life cycle and transmission to humans, information on the mechanisms of immune reactivity in snails against larval infection will be critical in understanding the genetic basis for host resistance...
  4. Genetic Analysis of Host Specificity in Schistosoma mansoni
    Tim J Anderson; Fiscal Year: 2013
    ..work demonstrates that both chemical recognition of the intermediate snail host and survival of parasites within snails follow a simple Mendelian pattern of inheritance...
  5. UNDERLYING MECHANISMS OF SCHISTOSOME/SNAIL COMPATIBILITY
    CHRISTOPHER JEFFREY BAYNE; Fiscal Year: 2012
    ..by the defense cells of the host and which are at least partialy responsible for the capacity of individual snails to resist infection...
  6. Potent Analgesic Conopeptides for Treatment of Chronic Spinal Cord Injury Pain
    Jacqueline Sagen; Fiscal Year: 2012
    ..Cone snails produce a number of novel peptides with selective ion channel blocking activity, and have become a major focus for ..
  7. CONUS PEPTIDES AND THEIR RECEPTOR TARGETS
    Baldomero M Olivera; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): There are >10,000 species of venomous marine snails belonging to the superfamily Conoidea;one group in the superfamily are the cone snails (Conus)...
  8. Maldi/ToF/ToF Mass Spectrometer for the University of Utah
    Chad C Nelson; Fiscal Year: 2010
    ..receptor proteins, development of fluorogenic peptide probes, discovery of novel neuropeptides from venomous snails, the role of sulfation patterns in proteoglycans, and discovery of unknown protein metal/ligand complexes...
  9. Lynx in organization and dynamics of nicotinic acetylcholine receptor complexes
    Julie M Miwa; Fiscal Year: 2013
    ..and functional similarities to the soluble nAChR ligands, 1-bungarotoxin and related toxins from snakes and snails. GPI-anchored membrane proteins can influence the distribution and mobility of surface receptors, through their ..
  10. Innate immune response to microbial PAMPs in the schistosome-transmitting snail,
    John T Sullivan; Fiscal Year: 2012
    ..These studies will utilize histological analysis of cell division in APOs of injected snails. Finally, with the use of microarray analysis, the pattern of gene expression in the APO in response to injection ..
  11. KLF8 Regulation of EMT Tumor Metastasis
    Jihe Zhao; Fiscal Year: 2013
    ..We will also evaluate role for other EMT regulators such as Snails, ZEBs and Twist in the regulation of metastasis by KLF8...
  12. The role of ppk ion channels in sensory detection
    KRISTIN E SCOTT; Fiscal Year: 2010
    ..elegans, and peptide sensing in snails. In Drosophila, there are 29 members of this gene family called pickpocket genes (ppk)...
  13. Experiment based genome mining of ribosomal natural products
    Bradley S Moore; Fiscal Year: 2013
    ..of ribosomally encoded toxins secreted by pathogenic bacteria such as Staphylococcus aureus, Bacillus cereus and Clostridium difficile as well as defensins produced by higher eukaryotes such as marine snails, primates and humans.
  14. Snail-Related Studies of Transmission and Control of Schistosomiasis in Kenya
    ERIC SAMUEL LOKER; Fiscal Year: 2013
    ..Schistosomes undergo obligatory larval development in snails in which they produce human- infective cercariae in prodigious numbers...
  15. Efficacious Screening of Peptidic Natural Products Using Drosophila
    FRANK MARI; Fiscal Year: 2010
    ..Components of the venom of cone snails elicit a wide range of neurophysiological responses and show great potential as neuronal probes...
  16. High Performance Sample Preparation Instrument
    Andres Villu Maricq; Fiscal Year: 2010
    ..will be invaluable in ongoing efforts to identify novel pharmacological compounds from rare species of Cones snails that modify the functions of the brain and heart...
  17. PARASITIC CASTRATION IN SNAILS--ROLE OF BIOGENIC AMINES
    TIMOTHY YOSHINO; Fiscal Year: 1999
    DESCRIPTION: (Adapted from the Applicant's Abstract): Parasitic castration of snails by larval trematodes, which manifests itself as histopathological changes in the gonads and/or lowered oviposition, represents one of the most dramatic ..
  18. Emergence and biological control of schistosomiasis
    Susanne H Sokolow; Fiscal Year: 2011
    ..Restoration of a native, edible, and marketable predator to control schistosome-transmitting snails may offer benefits for public health, ecosystem health, and poverty alleviation.
  19. Genomics-based Venom Studies Using the Cone Snail C. Bullatus
    MARK DOUGLAS YANDELL; Fiscal Year: 2013
    ..There is good reason to believe that collectively the cone snails still harbor a large repertoire of uncharacterized venoms (<100,000) of pharmacological interest...
  20. Sodium Channel Contratoxins Derived from Cone Snail Venoms
    Grzegorz Bulaj; Fiscal Year: 2007
    ..proof-of-concept contratoxin data, we will utilize conotoxins, peptide-based neurotoxins produced by venomous cone snails. Their exquisite potency and selectivity toward individual ion channels or receptors have been shown in many ..
  21. WETLAND URBANIZATION GRADIENTS AND VECTOR BORNE DISEASES
    JOSEPH KIESECKER; Fiscal Year: 2002
    ..In each wetland surveyed we willcollect information on physical and chemical conditions and will sample resident snails and amphibians. The identity and burden of trematodes will be determined for each animal collected...
  22. Molecular tools to monitor eradication of Schistosoma haematobium transmission
    Charles King; Fiscal Year: 2009
    ..To validate the established 525 bp Sh110/SmSl PCR technique as a species-specific means to identify snails infected with S. haematobium in ecosystems where related schistosome species are sympatric. 2...
  23. CONOPEPTIDE SODIUM CHANNEL BLOCKERS FOR CHRONIC PAIN
    James Garrett; Fiscal Year: 2000
    ..S.A.2. Clone genes and synthesize peptide products for novel Na channel modulators from snails using conserved regions of known Na channel modulators...
  24. BIOCHEMICAL CHARACTERIZATION OF CONUS TOXINS
    Baldomero Olivera; Fiscal Year: 1992
    The fish-hunting cone snails use their venoms to rapidly paralyze their much faster moving fish prey. These venoms contain multiple classes of paralytic toxins, as well as a large number of non-paralytic, but biologically active peptides...
  25. Neuropharmacology of Conophans and Hydroxyconophans
    FRANK MARI; Fiscal Year: 2007
    ..gladiator, C. mus and C. villepinii, so far). Components of the venom of cone snails elicit a wide range of neurophysiological responses and show great potential as therapeutic agents...
  26. ANALYSIS OF MOLLUSCAN FAUNAS AND ASTAN SCHISTOSOMIASIS
    George Davis; Fiscal Year: 1991
    It is a relatively new finding that there is a vast radiation of Triculini snails (Pomatiopsidae: Triculinae) throughout southern China actually or potentially transmitting Schistosoma and Paragonimus...
  27. POPULATION STRUCTURE OF SCHISTOSOMES AND HOST SNAILS
    DENNIS MINCHELLA; Fiscal Year: 2003
    ..abstract_text> ..
  28. POPULATION STRUCTURE OF SCHISTOSOMES AND HOST SNAILS
    DENNIS MINCHELLA; Fiscal Year: 2007
    ..aims of this project include: 1) Determining the relative nature of population subdivision for schistosomes and snails based on allelic data from microsatellites, and assessing how that genetic variation changes on both spatial and ..
  29. DESIGN OF CHEMOTHERAPEUTIC AGENTS
    Paul Talalay; Fiscal Year: 1980
    ..b>Snails of the species Biomphalaria glabrata refractory to schistosomal infections will be studied in an effort to uncover ..
  30. IN VITRO FLUOROTEST FOR ENVIRONMENTAL/AGROCHEMICALS
    Ann Cornell Bell; Fiscal Year: 2000
    ..a semi-intact preparation will also be used to screen for novel pesticides in venom libraries derived from Cone snails. These natural products (venom peptides) target specific invertebrate channels and receptors without effecting ..
  31. SCHISTOSOME-SNAIL COMPATIBILITY: UNDERLYING MECHANISMS
    Christopher Bayne; Fiscal Year: 1991
    ..mechanisms which result in transmission of the human blood fluke Schistosoma mansoni in certain individual host snails (Biomphalaria glabrata), and the failure of transmission in others...
  32. ECOLOGY AND TRANSMISSION OF S.JAPONICUM: PHILIPPINES
    Stephen McGarvey; Fiscal Year: 2004
    ..The model will include several species, their population biology and behavior, including humans, snails and animal reservoir hosts of S. japonicum...
  33. UNDERLYING MECHANISMS OF SCHISTOSOME/SNAIL COMPATIBILITY
    Christopher Bayne; Fiscal Year: 2001
    ..These experiments led to the premise that destruction of sporocysts in resistant snails may be due to a defective myeloperoxidase (MPO) that allows H2O2 to mediate killing, whereas MO hemocytes detoxify ..
  34. HUMAN POPULATION GROWTH IMPACT ON S. HAEMATOBIUM
    Charles King; Fiscal Year: 2005
    ..this project is to define means for effective interruption of parasite transmission from intermediate host Bulinus snails to definitive human hosts. While dynamic modeling predicts that mass treatment of S...
  35. SNAIL/SCHISTOSOME GENETIC INFLUENCES ON CERCARIOGENESIS
    Fred Lewis; Fiscal Year: 1991
    ..is focussed on elucidating (a) factors which control the ultimate level of cercarial production in susceptible snails, and (b) genetic determinants of the snail governing the outcome of the initial miracidial infection...
  36. Novel Pharmacological Agents from Conus regius
    FRANK MARI; Fiscal Year: 2003
    ..Cone snails are marine mollusks that use venom to capture their prey...
  37. Cone Snail Venom mGluRl Antagonist for Chronic Pain
    THOMAS HARTY; Fiscal Year: 2001
    ..The venoms of marine cone snails are unique collections of small peptides with biological activity at a number of ion channels and neurotransmitter ..
  38. INTERACTIONS OF A NOVEL LIGAND WITH A MODEL CHANNEL
    KI JOON SHON; Fiscal Year: 2001
    ..Conotoxins, peptide neurotoxins from Conus snails, are ideal molecules for providing a model system for studying ligand-receptor interactions...
  39. REGENERATION OF CENTRAL NERVOUS PATHWAYS
    STACIA MOFFETT; Fiscal Year: 1980
    ..The activity of these motor units will then be sampled in snails at various stages of regeneration and the extent of restoration of normal synaptic contacts and the degree of ..
  40. Plasma resistance factors in Biomphalaria glabrata
    John Sullivan; Fiscal Year: 2002
    ..Mechanisms responsible for no susceptibility to infection with Schistosoma mansoni in Biomphalaria glabrata snails are not well understood...
  41. Local Strategies for Schistosomiasis Control
    Robert Spear; Fiscal Year: 2006
    ....
  42. REMOTE SENSING AND GIS FOR SCHISTOSOMIASIS CONTROL
    Robert Spear; Fiscal Year: 2002
    ..surveillance of ecological conditions, altered by human interventions, that may provide habitat for amphibious snails. These snails are central to the transmission of human schistosomiasis in Sichuan and Jiangxi Provinces of China...
  43. Anti-pathogen responses in Biomphalaria glabrata
    COENRAAD M ADEMA; Fiscal Year: 2010
    ..A long tenn objective of this proposal is to characterize determinants for suitability of snails as host for schistosomes...
  44. Molecular Studies of Immunoparasitology in Snails
    Si Ming Zhang; Fiscal Year: 2010
    ..test our hypothesis, we propose to investigate whether TLR, Imd, and Jak/STAT signaling pathways are activated in snails after exposure to S. mansoni...
  45. Evo-epidemiology of Schistosoma mansoni in western Kenya
    ERIC LOKER; Fiscal Year: 2008
    ..mansoni in the Lake Victoria area. We will examine naturally infected snails to learn if they emit cercariae at unusual times of the day as a practical indicator of hybridization, and ..
  46. Anti-pathogen responses in Biomphalaria glabrata
    COENRAAD ADEMA; Fiscal Year: 2008
    ..A long term objective of this proposal is to characterize determinants for suitability of snails as host for schistosomes...
  47. BIOLOGY OF TREMATODE-SNAIL ASSOCIATIONS
    ERIC SAMUEL LOKER; Fiscal Year: 2010
    ..For most of the outlined studies, we emphasize before and after infection comparisons of snails of a particular strain, thus avoiding extraneous variables associated with inter-strain comparisons...
  48. MOLECULAR AND CELLULAR BASIS OF LENS DEVELOPMENT
    Jonathan J Henry; Fiscal Year: 2010
    ....
  49. EXPERIENCE AND DECISION-MAKING IN A REAL NEURAL NETWORK
    William Frost; Fiscal Year: 2003
    ..Each aim will employ the combined methodologies of electrophysiology and realistic computer simulations. ..
  50. Tissue-specific Overexpression of IKKbeta in mice
    PETER MELENDEZ; Fiscal Year: 2003
    ..These studies will determine whether tissue-specific increases in lKKb activity cause whole body insulin resistance and further ask whether lKKb activation in one tissue influences insulin sensitivity in others. ..
  51. IMMUNE PEPTIDES IN AEDES AEGYPTI
    TIMOTHY YOSHINO; Fiscal Year: 2002
    ....
  52. INTRACELLULAR PH RESPONSES OF CENTRAL CHEMORECEPTORS
    Robert Putnam; Fiscal Year: 2009
    ..We are studying the ways in which neurons respond to CO2 to identify novel drug targets and to test a new theory that this pathway involves several different signals. ..
  53. A gene map for Biomphalaria glabrata, a S. mansoni host
    Matty Knight; Fiscal Year: 2009
    ..Use will also be made of examining the heritability of polymorphic markers in progeny snails that segregate for resistance or susceptibility...
  54. Maternal/fetal genotype incompatibility in schizophrenia
    Janet Sinsheimer; Fiscal Year: 2003
    ..This proposal is important because it could lead to a concrete research model in which the essential genetic and environmental elements involved in the etiology of schizophrenia could be studied precisely. ..
  55. HOST GENETIC CORRELATES IN SCHISTOSOMIASIS
    Philip Loverde; Fiscal Year: 2004
    ..We expect to improve our understanding of the underlying genetic determinants of resistance to reinfection with schistosomiasis and disease progression. ..
  56. Motor Systems Supporting Pavlovian Conditioning
    Terry Crow; Fiscal Year: 2008
    ..These studies will help to elucidate general principles underlying the organization of polysensory neural systems generating behavior and their modification by learning. ..
  57. The mechanism of crosslinking by proteins that create adhesive gels
    Andrew Smith; Fiscal Year: 2006
    ..Three approaches will be used to test this. First, the glue proteins from terrestrial snails or slugs will be purified, then added to commercial gel-forming polymers...