holothuria

Summary

Summary: A genus of large SEA CUCUMBERS in the family Holothuriidae possessing thick body walls, a warty body surface, and microscopic ossicles.

Top Publications

  1. ncbi Phylogeography of the Atlanto-Mediterranean sea cucumber Holothuria (Holothuria) mammata: the combined effects of historical processes and current oceanographical pattern
    G H Borrero-Pérez
    Departamento de Ecología e Hidrología, Facultad de Biologia, Universidad de Murcia, Campus de Espinardo, 30100 Murcia, Spain
    Mol Ecol 20:1964-75. 2011
  2. ncbi The triterpene glycosides of Holothuria forskali: usefulness and efficiency as a chemical defense mechanism against predatory fish
    Séverine Van Dyck
    University of Mons UMONS, Marine Biology Laboratory, 6 Avenue du Champs de Mars, B 7000 Mons, Belgium
    J Exp Biol 214:1347-56. 2011
  3. ncbi Diversity and function of aerobic culturable bacteria in the intestine of the sea cucumber Holothuria leucospilota
    Xiaochi Zhang
    Graduate School of Science and Technology, Nagasaki University, Nagasaki 852 8521, Japan
    J Gen Appl Microbiol 58:447-56. 2012
  4. ncbi Two new cytotoxic triterpene glycosides from the sea cucumber Holothuria scabra
    Hua Han
    Research Center for Marine Drugs, School of Pharmacy, Second Military Medical University, Shanghai 200433, PR China
    Planta Med 75:1608-12. 2009
  5. ncbi Transdifferentiation in holothurian gut regeneration
    Vladimir S Mashanov
    Institute of Marine Biology FEB RAS, Palchevsky 17, 690041 Vladivostok, Russia
    Biol Bull 209:184-93. 2005
  6. ncbi A novel sulfated holostane glycoside from sea cucumber Holothuria leucospilota
    Hua Han
    Research Center for Marine Drugs, School of Pharmacy, Second Military Medical University, 325 Guo He Road, Shanghai 200433, P R China
    Chem Biodivers 7:1764-9. 2010
  7. ncbi T-antigen binding lectin with antibacterial activity from marine invertebrate, sea cucumber (Holothuria scabra): possible involvement in differential recognition of bacteria
    Nagaraj M Gowda
    Gene Lab, National Institute of Oceanography, Goa 403 004, India Division of Biochemical Sciences, National Chemical Laboratory, Pune 411 008, India
    J Invertebr Pathol 99:141-5. 2008
  8. ncbi Antifungal triterpene glycosides from the sea cucumber Holothuria (Microthele) axiloga
    Wei Hua Yuan
    Department of Pharmacy, Xijing Hospital, Fourth Military Medical University, Xi an 710032, PR China
    Planta Med 75:647-53. 2009
  9. pmc LPS-induced genes in intestinal tissue of the sea cucumber Holothuria glaberrima
    Francisco Ramírez-Gómez
    Department of Biology, University of Puerto Rico, Rio Piedras, San Juan, Puerto Rico
    PLoS ONE 4:e6178. 2009
  10. ncbi Tensilin-like stiffening protein from Holothuria leucospilota does not induce the stiffest state of catch connective tissue
    Masaki Tamori
    W3 42, Department of Biological Sciences, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, O okayama 2 12 1, Tokyo 152 8551, Japan
    J Exp Biol 209:1594-602. 2006

Research Grants

  1. Nervous system regeneration, molecular basis in echinoderms
    JOSE E GARCIA-ARRARAS; Fiscal Year: 2013

Scientific Experts

Detail Information

Publications114 found, 100 shown here

  1. ncbi Phylogeography of the Atlanto-Mediterranean sea cucumber Holothuria (Holothuria) mammata: the combined effects of historical processes and current oceanographical pattern
    G H Borrero-Pérez
    Departamento de Ecología e Hidrología, Facultad de Biologia, Universidad de Murcia, Campus de Espinardo, 30100 Murcia, Spain
    Mol Ecol 20:1964-75. 2011
    We assessed the genetic structure of populations of the widely distributed sea cucumber Holothuria (Holothuria) mammata Grube, 1840, and investigated the effects of marine barriers to gene flow and historical processes...
  2. ncbi The triterpene glycosides of Holothuria forskali: usefulness and efficiency as a chemical defense mechanism against predatory fish
    Séverine Van Dyck
    University of Mons UMONS, Marine Biology Laboratory, 6 Avenue du Champs de Mars, B 7000 Mons, Belgium
    J Exp Biol 214:1347-56. 2011
    ..In particular, Holothuria forskali contains 26 saponins in its Cuvierian tubules and 12 in its body wall...
  3. ncbi Diversity and function of aerobic culturable bacteria in the intestine of the sea cucumber Holothuria leucospilota
    Xiaochi Zhang
    Graduate School of Science and Technology, Nagasaki University, Nagasaki 852 8521, Japan
    J Gen Appl Microbiol 58:447-56. 2012
    ..Here, we isolated 141 bacterial strains under aerobic conditions using various media from the intestine of Holothuria leucospilota, a common sea cucumber in Japanese warm waters...
  4. ncbi Two new cytotoxic triterpene glycosides from the sea cucumber Holothuria scabra
    Hua Han
    Research Center for Marine Drugs, School of Pharmacy, Second Military Medical University, Shanghai 200433, PR China
    Planta Med 75:1608-12. 2009
    ..scabraside A (1) and B (2), and a structurally known compound (3), were isolated from the sea cucumber Holothuria scabra (Holothuriidae) collected from the South China Sea...
  5. ncbi Transdifferentiation in holothurian gut regeneration
    Vladimir S Mashanov
    Institute of Marine Biology FEB RAS, Palchevsky 17, 690041 Vladivostok, Russia
    Biol Bull 209:184-93. 2005
    ..from the mesodermally derived mesothelium and the endodermally derived epithelium of the cloacal lining, respectively. Our data suggest that differentiated cells of echinoderms are capable of transdifferentiation into other cell types...
  6. ncbi A novel sulfated holostane glycoside from sea cucumber Holothuria leucospilota
    Hua Han
    Research Center for Marine Drugs, School of Pharmacy, Second Military Medical University, 325 Guo He Road, Shanghai 200433, P R China
    Chem Biodivers 7:1764-9. 2010
    ..related structurally known compounds holothurin B(2) (2) and holothurin B (3), was isolated from sea cucumber Holothuria leucospilota collected from the South China Sea...
  7. ncbi T-antigen binding lectin with antibacterial activity from marine invertebrate, sea cucumber (Holothuria scabra): possible involvement in differential recognition of bacteria
    Nagaraj M Gowda
    Gene Lab, National Institute of Oceanography, Goa 403 004, India Division of Biochemical Sciences, National Chemical Laboratory, Pune 411 008, India
    J Invertebr Pathol 99:141-5. 2008
    ..this article, we report a study of a lectin (HSL) involved in immune response in the echinoderm, sea cucumber (Holothuria scabra)...
  8. ncbi Antifungal triterpene glycosides from the sea cucumber Holothuria (Microthele) axiloga
    Wei Hua Yuan
    Department of Pharmacy, Xijing Hospital, Fourth Military Medical University, Xi an 710032, PR China
    Planta Med 75:647-53. 2009
    ..2), and pervicoside D (3), together with a known saponin, holothurin B ( 4) were isolated from the sea cucumber Holothuria (Microthele) axiloga H. L. Clark...
  9. pmc LPS-induced genes in intestinal tissue of the sea cucumber Holothuria glaberrima
    Francisco Ramírez-Gómez
    Department of Biology, University of Puerto Rico, Rio Piedras, San Juan, Puerto Rico
    PLoS ONE 4:e6178. 2009
    ..Our study employs a non-conventional model, the echinoderm Holothuria glaberrima, to identify intestinal molecules expressed after an immune challenge presented by an intra-coelomic ..
  10. ncbi Tensilin-like stiffening protein from Holothuria leucospilota does not induce the stiffest state of catch connective tissue
    Masaki Tamori
    W3 42, Department of Biological Sciences, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, O okayama 2 12 1, Tokyo 152 8551, Japan
    J Exp Biol 209:1594-602. 2006
    ..We purified a similar protein, H-tensilin, from Holothuria leucospilota, which belongs to a different family to C. frondosa...
  11. ncbi Purification and characterization of a T-antigen specific lectin from the coelomic fluid of a marine invertebrate, sea cucumber (Holothuria scabra)
    Nagaraj M Gowda
    Gene Laboratory, National Institute of Oceanography, Dona Paula, Goa 403 004, India
    Fish Shellfish Immunol 24:450-8. 2008
    A novel lectin was purified from the coelomic fluid of the sea cucumber Holothuria scabra (HSL), subjected to bacterial challenge. HSL is a monomeric glycoprotein of molecular mass 182 kDa...
  12. ncbi A new cytotoxic lanostane-type triterpene glycoside from the sea cucumber Holothuria impatiens
    Peng Sun
    Research Center for Marine Drugs, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, PR China
    Chem Biodivers 4:450-7. 2007
    A new lanostane-type triterpene glycoside, impatienside A (1), was isolated from the sea cucumber Holothuria impatiens, together with a structurally related, known compound, bivittoside D (2)...
  13. ncbi Immune-related genes associated with intestinal tissue in the sea cucumber Holothuria glaberrima
    Francisco Ramírez-Gómez
    Department of Biology, University of Puerto Rico, P O Box 23360, UPR Station, Rio Piedras, San Juan, PR 00931 3360
    Immunogenetics 60:57-71. 2008
    ..sequence tags (ESTs) from three cDNA libraries of normal and regenerating intestinal tissue of the sea cucumber Holothuria glaberrima and found 22 putative immune-related genes...
  14. ncbi Identification of nerve plexi in connective tissues of the sea cucumber Holothuria glaberrima by using a novel nerve-specific antibody
    Carlos A Díaz-Balzac
    Biology Department, University of Puerto Rico, Rio Piedras Campus, Rio Piedras, Puerto Rico 00931
    Biol Bull 213:28-42. 2007
    ..We have now produced a monoclonal antibody (RN1) that labels a nervous system component of the sea cucumber Holothuria glaberrima. Western blots show that our antibody recognizes a major band of 66 kDa and a minor band of 53 kDa...
  15. ncbi Spherulocytes in the echinoderm Holothuria glaberrima and their involvement in intestinal regeneration
    JOSE E GARCIA-ARRARAS
    Biology Department, University of Puerto Rico, Rio Piedras, Puerto Rico
    Dev Dyn 235:3259-67. 2006
    The holothuroid echinoderm Holothuria glaberrima can regenerate its intestine after a process of evisceration. Spherule-containing cells, the spherulocytes, appear to be associated with intestinal regeneration...
  16. pmc Regeneration of the radial nerve cord in the sea cucumber Holothuria glaberrima
    José E San Miguel-Ruiz
    Department of Biology, University of Puerto Rico, Rio Piedras, Puerto Rico
    BMC Dev Biol 9:3. 2009
    ..Echinoderms, with their amazing regenerative capacities could serve as model systems; however, very few studies have been done to study the regeneration of their nervous system...
  17. ncbi Nobilisides A - C, three new triterpene glycosides from the sea cucumber Holothuria nobilis
    Jun Wu
    Research Center for Marine Drugs, College of Pharmacy, Second Military Medical University, Shanghai, PR China
    Planta Med 72:932-5. 2006
    Three new triterpene glycosides, named nobilisides A ( 1), B ( 2) and C ( 3), were isolated from the sea cucumber Holothuria nobilis Selenka. Their structures were deduced by extensive spectral analysis and chemical evidence...
  18. pmc Common cellular events occur during wound healing and organ regeneration in the sea cucumber Holothuria glaberrima
    José E San Miguel-Ruiz
    Department of Biology, University of Puerto Rico, Rio Piedras, Puerto Rico
    BMC Dev Biol 7:115. 2007
    ..We have now used the sea cucumber Holothuria glaberrima to address this question.
  19. pmc Distinct profiles of expressed sequence tags during intestinal regeneration in the sea cucumber Holothuria glaberrima
    Carmencita Rojas-Cartagena
    Department of Biology, Rio Piedras Campus, San Juan, Puerto Rico
    Physiol Genomics 31:203-15. 2007
    ..The sea cucumber Holothuria glaberrima represents an excellent model to dissect and characterize the molecular events during intestinal ..
  20. ncbi Myogenesis during holothurian intestinal regeneration
    Gisela Murray
    Biology Department, University of Puerto Rico, 00931, Rio Piedras, PR, 00931, Puerto Rico
    Cell Tissue Res 318:515-24. 2004
    ..We are interested in intestinal regeneration in the sea cucumber, Holothuria glaberrima, and focus here on the regeneration of intestinal muscle components...
  21. ncbi Iamia majanohamensis gen. nov., sp. nov., an actinobacterium isolated from sea cucumber Holothuria edulis, and proposal of Iamiaceae fam. nov
    Midori Kurahashi
    Institute of Molecular and Cellular Biosciences, The University of Tokyo, Yayoi 1 1 1, Bunkyo ku, Tokyo 113 0032, Japan
    Int J Syst Evol Microbiol 59:869-73. 2009
    A novel, Gram-positive bacterial strain, F12(T), was isolated from the abdominal epidermis of a sea cucumber, Holothuria edulis, collected from seawater off the coast of Japan...
  22. ncbi A novel stiffening factor inducing the stiffest state of holothurian catch connective tissue
    Akira Yamada
    Kobe Advanced ICT Research Center, National Institute of Information and Communications Technology, Kobe, Hyogo 651 2492, Japan
    J Exp Biol 213:3416-22. 2010
    ..A stiffening protein, tensilin, has been isolated from some sea cucumbers (Cucumaria frondosa and Holothuria leucospilota)...
  23. ncbi AChE and EROD activities in two echinoderms, Holothuria leucospilota and Holoturia atra (Holothuroidea), in a coral reef (Reunion Island, South-western Indian Ocean)
    Joanna Kolasinski
    Laboratoire d Ecologie Marine, Universite de la Reunion, La Reunion, France
    J Environ Sci Health A Tox Hazard Subst Environ Eng 45:699-708. 2010
    AChE and EROD activities were investigated in two holothurian species, Holothuria leucospilota and Holoturia atra, from a tropical coral reef...
  24. ncbi Molecular phylogeny of coral-reef sea cucumbers (Holothuriidae: Aspidochirotida) based on 16S mitochondrial ribosomal DNA sequence
    Alexander M Kerr
    Department of Ecology and Evolutionary Biology, Osborn Zoölogical Laboratories, Yale University, New Haven, CT 06520, U S A
    Mar Biotechnol (NY) 7:53-60. 2005
    ..Most notably, the genus Holothuria appears paraphyletic...
  25. ncbi Molecular systematics of the genus Holothuria in the Mediterranean and Northeastern Atlantic and a molecular clock for the diversification of the Holothuriidae (Echinodermata: Holothuroidea)
    Giomar Helena Borrero-Pérez
    Departamento de Ecología e Hidrología, Facultad de Biologia, Universidad de Murcia, Campus de Espinardo, 30100 Murcia, Spain
    Mol Phylogenet Evol 57:899-906. 2010
    This work investigates the systematics of the genus Holothuria in the Mediterranean Sea and Northeastern Atlantic in the light of a wider molecular phylogenetic hypothesis of Holothuriidae, and it also provides a time-scale for the family ..
  26. ncbi [The echinoderms (Echinodermata) from El Salvador]
    José Enrique Barraza
    Ministerio de Medio Ambiente y Recursos Naturales, Dirección de Patrimonio Natural Col y Calle Las Mercedes, Plantel ISTA, San Salvador, El Salvador
    Rev Biol Trop 53:139-46. 2005
    ..A total of 37 species and six genera are reported. The most abundant echinoderms in rocky shores were: Phataria unifascialis, Echinometra vanbrunti, Holothuria kefersteini, as well as Astropecten armatus in soft bottoms.
  27. ncbi [Antithrombotic mechanisms of holothurian glycosaminoglycan extracted from sea cucumber]
    Wei zhang Shen
    Shanghai Institute of Haematology, Ruijin Hospital, Shanghai Jiaotong University, Shanghai 200025, China
    Zhonghua Xue Ye Xue Za Zhi 27:579-83. 2006
    ..To investigate the antithrombotic mechanisms of holothurian glycosaminoglycan (GAG) extracted from sea cucumber...
  28. ncbi Destruction of a Holothuria scabra population by overfishing at Abu Rhamada Island in the Red Sea
    Mohamed Hamza Hasan
    National Institute of Oceanography and Fisheries, Red Sea and Gulfs of Suez and Aqaba Branch, P O Box 182 Suez, Egypt
    Mar Environ Res 60:489-511. 2005
    Populations of Holothuria scabra at Abu Rhamada Island were investigated during 52 months, from July 1999 to October 2003...
  29. ncbi Screening of marine extracts for schistosomicidal activity in vitro. Isolation of the triterpene glycosides echinosides A and B with potential activity from the Sea Cucumbers Actinopyga echinites and Holothuria polii
    Farouk R Melek
    Natural Compounds Department, National Research Center, Giza, Egypt
    Pharm Biol 50:490-6. 2012
    ..The reported reduced cure rates, the failure of treatment after PZQ administration in patients and the existence of resistant parasite strains, reinforce the need to rapidly discover new effective molecules against Schistosoma parasite...
  30. pmc Calbindin-D32k is localized to a subpopulation of neurons in the nervous system of the sea cucumber Holothuria glaberrima (Echinodermata)
    Carlos A Díaz-Balzac
    Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, United States of America
    PLoS ONE 7:e32689. 2012
    ..study we investigated the presence and distribution of members of the calbindin subfamily in the sea cucumber Holothuria glaberrima (Selenka, 1867)...
  31. ncbi Chemical fingerprinting and phylogenetic mapping of saponin congeners from three tropical holothurian sea cucumbers
    Karen Grace V Bondoc
    The Marine Science Institute, University of the Philippines, Diliman, Quezon City, Philippines Electronic address
    Comp Biochem Physiol B Biochem Mol Biol 166:182-93. 2013
    ..MS fingerprint showed the presence of holothurinosides, which was observed for the first time in other Holothuria genera besides the basally positioned Holothuria forskali...
  32. pmc Sea cucumber aquaculture in the Western Indian ocean: challenges for sustainable livelihood and stock improvement
    Hampus Eriksson
    Department of Systems Ecology, Stockholm University, Stockholm, Sweden
    Ambio 41:109-21. 2012
    ..The tropical sandfish (Holothuria scabra) has, in this context, been reared and produced with mixed success...
  33. ncbi Effect of diel activity patterns and harvesting pressure on the diversity and biomass of sea cucumbers in Marovo Lagoon, Solomon Islands
    Christine Buckius
    Centre for Water Studies, University of Queensland, St Lucia, QLD, Australia
    Environ Manage 45:963-73. 2010
    ..Day time and nocturnal transects revealed a mean abundance of 32.4 (SD = 5.3) low value species per ha (e.g. Holothuria atra, H. edulis, H. coluber and Thelenota anax) and 15.2 (SD = 2.7) high value species per ha (e.g. H...
  34. ncbi New virescenosides from the marine-derived fungus Acremonium striatisporum
    Shamil S Afiyatullov
    Pacific Institute of Bioorganic Chemistry, Far East Branch of the Russian Academy of Sciences, Prospect 100 let Vladivostoku, 159, Vladivostok 690022, Russian Federation
    Nat Prod Commun 6:1063-8. 2011
    ..Virescenosides Z4-Z8 contain rare altruronic acid 4C1 and 1C4 conformations as their carbohydrate components. Virescenosides Z5 and Z7 exhibit an unusual 16-chloro, 15-hydroxyethylgroup as their side chains...
  35. ncbi Posttraumatic regeneration involves differential expression of long terminal repeat (LTR) retrotransposons
    Vladimir S Mashanov
    Department of Biology, University of Puerto Rico, San Juan, Puerto Rico
    Dev Dyn 241:1625-36. 2012
    ..Although retroelements are known to play significant roles in embryogenesis, stress reactions, and disease progression, they have never been studied in the context of animal regeneration...
  36. ncbi Holothuria grisea agglutinin (HGA): the first invertebrate lectin with anti-inflammatory effects
    Raniere da M Moura
    Department of Biochemistry and Molecular Biology, Federal University of Ceara, Campus do Pici, S N, bloco 907, Fortaleza, CE, 60451 970, Brazil
    Fundam Clin Pharmacol 27:656-68. 2013
    b>Holothuria grisea agglutinin (HGA) is a dimeric lectin of molecular mass 228 kDa by gel filtration with monomers of 105 kDa by SDS-PAGE. The lectin is highly thermostable as it retains full activity for 1 h at 70 °C...
  37. ncbi Fucosylated chondroitin sulfates from the body wall of the sea cucumber Holothuria forskali: conformation, selectin binding, and biological activity
    Charalampos G Panagos
    From the EaStCHEM School of Chemistry, Joseph Black Building, The King s Buildings, University of Edinburgh, Edinburgh EH9 3JJ, United Kingdom
    J Biol Chem 289:28284-98. 2014
    Fucosylated chondroitin sulfate (fCS) extracted from the sea cucumber Holothuria forskali is composed of the following repeating trisaccharide unit: → 3)GalNAcβ4,6S(1 → 4) [FucαX(1 → 3)]GlcAβ(1 →, where X stands for different ..
  38. ncbi Acid-base physiology response to ocean acidification of two ecologically and economically important holothuroids from contrasting habitats, Holothuria scabra and Holothuria parva
    Marie Collard
    Laboratoire de Biologie Marine, Universite Libre de Bruxelles, 50 Avenue F D Roosevelt, 1050, Brussels, Belgium
    Environ Sci Pollut Res Int 21:13602-14. 2014
    ..7 and 7.4) on two sea cucumbers collected in SW Madagascar, Holothuria scabra, a high commercial value species living in the seagrass meadows, and H. parva, inhabiting the mangroves...
  39. ncbi Constituents of holothuroidea, 12. Isolation and structure of glucocerebrosides from the sea cucumber Holothuria pervicax
    Koji Yamada
    Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan
    Chem Pharm Bull (Tokyo) 50:1467-70. 2002
    ..species HPC-1 and HPC-2, from the less polar lipid fraction of a chloroform/methanol extract of the sea cucumber Holothuria pervicax...
  40. ncbi Antiviral activity of Holothuria sp. a sea cucumber against herpes simplex virus type 1 (HSV-1)
    F Farshadpour
    The Persian Gulf Marine Biotechnology Research Center, Bushehr University of Medical Sciences, Bushehr, Iran
    Eur Rev Med Pharmacol Sci 18:333-7. 2014
    ..Sea cucumber is among the marine organisms a traditional food item in Asia with different applications in traditional medicine...
  41. ncbi Engagement of the periesophageal ring during Holothuria polii response to erythrocyte injection
    G D'Ancona Lunetta
    Istituto di Istologia ed Embrologia, Facolta di Scienze, MM FF NN, Universita di Palermo, Italy
    Eur J Histochem 46:185-94. 2002
    In Holothuria polii, the periesophageal ring is an important organ supplying spherule cells after stimulation with foreign material...
  42. ncbi Holothuria (Selenkothuria) parvispinea n. sp. (Echinodermata, Hololthuroidea, Holothuriidae) with key to the sub-genus Selenkothuria
    Claude Massin
    Department of Recent Invertebrates, Malacology, Royal Belgian Institute of Natural Sciences, 29 Vautierstreet, 1000 Brussels, Belgium email
    Zootaxa 3609:343-8. 2013
    Description of a new species from Australia, belonging to the subgenus Selenkothuria (Holothuria, Aspidochirotida). A dichotomous key of the thirteen valid species included in the subgenus is also given. The species H...
  43. ncbi Bio-distribution and pharmacokinetics of nobiliside A-loaded liposome following intravenous administration in rats
    Yang Xiong
    Department of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, China Electronic address
    J Chromatogr B Analyt Technol Biomed Life Sci 962:132-40. 2014
    Nobiliside A (Nob) is a new triterpenoid saponin separated from Holothuria noblilis...
  44. ncbi Instantaneous adhesion of Cuvierian tubules in the sea cucumber Holothuria forskali
    Mélanie Demeuldre
    Research Institute for Biosciences, Biology of Marine Organisms and Biomimetics, University of Mons UMONS, Mons 7000, Belgium
    Biointerphases 9:029016. 2014
    ..The adhesive epithelium-the mesothelium-and the sticky material it produces were studied in the species Holothuria forskali using different microscopy techniques (light microscopy, transmission electron microscopy, scanning ..
  45. ncbi RGD-containing peptides inhibit intestinal regeneration in the sea cucumber Holothuria glaberrima
    Arelys Cabrera-Serrano
    Biology Department, University of Puerto Rico, Rio Piedras Campus, Puerto Rico
    Dev Dyn 231:171-8. 2004
    The sea cucumber Holothuria glaberrima is an echinoderm capable of regenerating its viscera. Previous studies from our group have shown a striking remodeling of the extracellular matrix (ECM) during intestinal regeneration...
  46. ncbi Contribution of mesenterial muscle dedifferentiation to intestine regeneration in the sea cucumber Holothuria glaberrima
    Ann Ginette Candelaria
    Department of Biology, University of Puerto Rico, Rio Piedras, Puerto Rico, PR 00931
    Cell Tissue Res 325:55-65. 2006
    ..In the species Holothuria glaberrima, intestinal regeneration involves the formation of thickenings along the free mesentery edge; these ..
  47. ncbi Organochlorine pollutants in Western Antarctic Peninsula sediments and benthic deposit feeders
    Lin Zhang
    Graduate School of Oceanography, University of Rhode Island, Narragansett, Rhode Island 02882 1197, United States
    Environ Sci Technol 47:5643-51. 2013
    ..PCBs and OCPs in the holothurians were in equilibrium with those in the porewater...
  48. pmc High-value components and bioactives from sea cucumbers for functional foods--a review
    Sara Bordbar
    Faculty of Food Science and Technology, Universiti Putra Malaysia, Serdang, Selangor 43400, Malaysia
    Mar Drugs 9:1761-805. 2011
    ....
  49. pmc Proteases from the regenerating gut of the holothurian Eupentacta fraudatrix
    Nina E Lamash
    A V Zhirmunsky Institute of Marine Biology of the Far Eastern Branch of the Russian Academy of Sciences, Vladivostok, Russia
    PLoS ONE 8:e58433. 2013
    ..The role of the detected proteases in the regeneration processes of holothurians is discussed...
  50. ncbi Extracellular matrix remodeling and metalloproteinase involvement during intestine regeneration in the sea cucumber Holothuria glaberrima
    José L Quiñones
    Department of Biology, University of Puerto Rico, Rio Piedras, Puerto Rico 00931, USA
    Dev Biol 250:181-97. 2002
    The sea cucumber, Holothuria glaberrima, has the capacity to regenerate its internal organs...
  51. pmc Comparison of physicochemical characteristics and anticoagulant activities of polysaccharides from three sea cucumbers
    Lan Luo
    State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China
    Mar Drugs 11:399-417. 2013
    ..activities, we have isolated three types of polysaccharides from the body wall of the three sea cucumbers Holothuria edulis, Apostichopus japonicas and Holothuria nobilis...
  52. ncbi Screening of microbial contamination and antimicrobial activity of sea cucumber Holothuria polii
    Nahla E E Omran
    1Invertebrate Unit, Department of Zoology, Faculty of Science, Tanta University, Tanta, Egypt
    Toxicol Ind Health 29:944-54. 2013
    Microbiological studies were carried out on microbial contamination and antimicrobial activity of sea cucumber Holothuria polii collected from Mediterranean Sea at Abu-kir shore of Alexandria, Egypt...
  53. ncbi Telomeric localization of the vertebrate-type hexamer repeat, (TTAGGG)n, in the wedgeshell clam Donax trunculus and other marine invertebrate genomes
    Miroslav Plohl
    Department of Molecular and Cell Biology, Institut de Biologia Molecular de Barcelona, CSIC, E 08034 Barcelona, Spain
    J Biol Chem 277:19839-46. 2002
    ..and other marine invertebrates, genomic DNA from the mussel Mytilus galloprovincialis and the echinoderm Holothuria tubulosa was also analyzed...
  54. ncbi The morphology of the digestive tract and respiratory organs of the holothurian Cladolabes schmeltzii (Holothuroidea, Dendrochirotida)
    Ya O Kamenev
    AV Zhirmunsky Institute of Marine Biology of the Far Eastern Branch of the Russian Academy of Sciences, Vladivostok, Russia
    Tissue Cell 45:126-39. 2013
    ..The coelomic epithelium of the intestine and the respiratory trees consists of peritoneal and myoepithelial cells...
  55. ncbi Bioactive compounds, antioxidant potential, and hepatoprotective activity of sea cucumber (Holothuria atra) against thioacetamide intoxication in rats
    Amr Y Esmat
    Department of Biochemistry, Faculty of Science, Ain Shams University, Cairo, Egypt
    Nutrition 29:258-67. 2013
    The identification of the active phenolic compounds in the mixed extract of sea cucumber (Holothuria atra) body wall by high-performance liquid chromatography and an assessment of its hepatoprotective activity against thioacetamide-..
  56. ncbi Lipopolysaccharides induce intestinal serum amyloid A expression in the sea cucumber Holothuria glaberrima
    Pedro G Santiago-Cardona
    Department of Biology, University of Puerto Rico, UPR Station, PR 00931 3360, Rio Piedras, Puerto Rico
    Dev Comp Immunol 27:105-10. 2003
    ..previously characterized the first invertebrate homolog of serum amyloid A (SAA) proteins in the sea cucumber Holothuria glaberrima, where its expression is associated with intestinal regeneration, suggesting a possible involvement ..
  57. ncbi Characterization of the adhesive from cuvierian tubules of the sea cucumber Holothuria forskali (Echinodermata, Holothuroidea)
    Sonia DeMoor
    Marine Biology Laboratory, University of Mons Hainaut, 6 Avenue du Champ de Mars, B 7000 Mons, Belgium
    Mar Biotechnol (NY) 5:45-57. 2003
    ..The cellular origin and composition of the Cuvierian tubule adhesive were investigated in the species Holothuria forskali by studying prints left on the substratum after mechanical detachment of the tubule...
  58. ncbi Discovery and widespread occurrence of polyhalogenated 1,1'-dimethyl-2,2'-bipyrroles (PDBPs) in marine biota
    Carolin Hauler
    University of Hohenheim, Institute of Food Chemistry, Garbenstraße 28, 70599 Stuttgart, Germany
    Environ Pollut 178:329-35. 2013
    ..Thirteen of these new PDBPs were also detected in an Australian sea cucumber (Holothuria sp.)...
  59. ncbi The spherule cells of Holothuria polii Delle Chiaie, 1823 (Aspidochirota, Holothuroidea) during brown body formation: an ultrastructural study
    P Pagliara
    Department of Biology, University of Lecce, Italy
    J Submicrosc Cytol Pathol 35:295-301. 2003
    ..Morphological modifications of spherule cells were studied in Holothuria polii following the induction of brown body formation by intracoelomic injection of sheep erythrocytes...
  60. ncbi Antioxidant and cytotoxic properties of two sea cucumbers, Holothuria edulis lesson and Stichopus horrens Selenka
    O Y Althunibat
    Department of Biomedical Science, International Islamic University, Kuantan, Pahang, Malaysia
    Acta Biol Hung 64:10-20. 2013
    ..the antioxidant and cytotoxic properties of aqueous and organic extracts from two sea cucumber species, Holothuria edulis Lesson (Holothuriidae) and Stichopus horrens Selenka (Stichopodidae)...
  61. ncbi Kinetics and thermodynamics of glycans and glycoproteins binding to Holothuria scabra lectin: a fluorescence and surface plasmon resonance spectroscopic study
    Nagaraj M Gowda
    Department of Anesthesiology and Critical Care Medicine, Division of Allergy and Clinical Immunology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA
    J Fluoresc 23:1147-55. 2013
    b>Holothuria scabra produces a monomeric lectin (HSL) of 182 kDa. HSL showed strong antibacterial activity and induced bacterial agglutination under in vitro conditions, indicating its role in animals' innate immune responses...
  62. ncbi Anticancer activity and mediation of apoptosis in human HL-60 leukaemia cells by edible sea cucumber (Holothuria edulis) extract
    W A J P Wijesinghe
    School of Marine Biomedical Sciences, Jeju National University, Jeju 690 756, Republic of Korea
    Food Chem 139:326-31. 2013
    ..In this study, edible sea cucumber Holothuria edulis was evaluated for its in vitro anticancer potential...
  63. pmc Cell dedifferentiation and epithelial to mesenchymal transitions during intestinal regeneration in H. glaberrima
    JOSE E GARCIA-ARRARAS
    Biology Department, University of Puerto Rico, Rio Piedras 00931, Puerto Rico
    BMC Dev Biol 11:61. 2011
    ..We have previously used several cellular markers to characterize the cells involved in the regeneration of the intestine in the sea cucumber Holothuria glaberrima.
  64. pmc Changes in holothurian coelomocyte populations following immune stimulation with different molecular patterns
    Francisco Ramírez-Gómez
    Department of Biology, University of Puerto Rico, P O Box 23360, UPR Station, Rio Piedras, San Juan, PR 00931 3360, USA
    Fish Shellfish Immunol 29:175-85. 2010
    ..In the sea cucumber Holothuria glaberrima, four different coelomocyte types were readily distinguished using morphological, histochemical and ..
  65. ncbi A new endosymbiotic bivalve (Heterodonta: Galeommatoidea), from Pacific holothurians
    G A Bristow
    Department of Biology, University of Bergen, N 5020 Bergen, Norway
    J Parasitol 96:532-4. 2010
    A fourth known species of Entovalva (Mollusca: Galeommatoidea), found in the esophagus of Holothuria spinifera and Holothuria leucospilota from Nha Trang Bay, Viet Nam, is described...
  66. ncbi Organization of glial cells in the adult sea cucumber central nervous system
    Vladimir S Mashanov
    Department of Biology, University of Puerto Rico, Rio Piedras, PR 00936 8377, Puerto Rico
    Glia 58:1581-93. 2010
    ..confocal, and electron microscopy, we demonstrate here that the central nervous system of the sea cucumber Holothuria glaberrima possesses a major non-neuronal cell type, which shares striking similarities with the radial glia of ..
  67. doi Genetic barcoding of commercial Bêche-de-mer species (Echinodermata: Holothuroidea)
    Sven Uthicke
    Australian Institute of Marine Science, PMB No 3, Townsville, Qld 4810, Australia Department of Anatomy and Histology, F13, University of Sydney, Sydney, NSW 2006, Australia Ecomar Laboratory, Universite de la Reunion, Saint Denis 97715, Reunion, France
    Mol Ecol Resour 10:634-46. 2010
    ..Sequence data showed that large (deep) and small (shallow) morphotypes of Holothuria atra are the same species, but suggested potential cryptic species within this taxon...
  68. pmc Localization of secondary metabolites in marine invertebrates: contribution of MALDI MSI for the study of saponins in Cuvierian tubules of H. forskali
    Séverine Van Dyck
    Laboratoire de Biologie Marine, Universite de Mons, Mons, Belgium
    PLoS ONE 5:e13923. 2010
    ..In the present study, the precise localization of saponins in the Ct of Holothuria forskali is investigated...
  69. ncbi Genetic diversity and connectivity remain high in Holothuria polii (Delle Chiaje 1823) across a coastal lagoon-open sea environmental gradient
    Carlos Vergara-Chen
    Departamento de Ecología e Hidrología, Facultad de Biologia, Universidad de Murcia, Campus de Espinardo, 30100 Murcia, Spain
    Genetica 138:895-906. 2010
    ..This study investigates the genetic structure of Holothuria polii at a micro-geographic scale across the Mar Menor coastal lagoon and nearby marine areas, estimating the ..
  70. ncbi Synthesis of the glycan moiety of ganglioside HPG-7 with an unusual trimer of sialic acid as the inner sugar residue
    Yuki Iwayama
    Department of Applied Bioorganic Chemistry, Gifu University, 1 1 Yanagido, Gifu shi, Gifu 501 1193, Japan
    Chem Commun (Camb) 47:9726-8. 2011
    The glycan moiety of ganglioside HPG-7, isolated from the sea cucumber (Holothuria pervicax), was synthesized for the first time...
  71. ncbi Chemical composition and nutritional quality of sea cucumbers
    Jing Wen
    Key Laboratory of Marine Bio resources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China
    J Sci Food Agric 90:2469-74. 2010
    ..and nutritional quality of eight common sea cucumbers (Stichopus herrmanni, Thelenota ananas, Thelenota anax, Holothuria fuscogilva, Holothuria fuscopunctata, Actinopyga mauritiana, Actinopyga caerulea and Bohadschia argus) were ..
  72. ncbi DNA integrity determination in marine invertebrates by Fast Micromethod
    Zeljko Jaksić
    Laboratory for Marine Molecular Toxicology, Center for Marine Research, Ruder Boskovic Institute, G Paliage 5, HR 52210 Rovinj, Croatia
    Aquat Toxicol 65:361-76. 2003
    ..5. The induction of DNA damage and loss of DNA integrity was measured in native DNA isolated from cotton-spinner Holothuria tubulosa, marine sponge Suberites domuncula cells and mussel M. galloprovincialis gills homogenate...
  73. ncbi [Distribution and density of two holothurian species in Cubagua Island, Venezuela]
    Alejandro Tagliafico
    Escuela de Ciencias Aplicadas del Mar, Núcleo de Nueva Esparta, Universidad de Oriente, Boca de Rio, Isla de Margarita, Venezuela
    Rev Biol Trop 59:843-52. 2011
    ..the distribution, abundance and population structure of two commercial holothurians Isostichopus badionotus and Holothuria mexicana in Cubagua Island shores. A total of 52 stations were studied around the island during the year 2008...
  74. ncbi Pharmacological action of the heptapeptide GFSKLYFamide in the muscle of the sea cucumber Holothuria glaberrima (Echinodermata)
    L Díaz-Miranda
    Department of Biology, University of Puerto Rico, Rio Piedras 00931
    Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 110:171-6. 1995
    ..Our investigation provides additional evidence indicating that GFSKLYFa might be a neurotransmitter acting at the neuromuscular junctions of the sea cucumber Holothuria glaberrima.
  75. ncbi Structure and cytotoxicity of a new lanostane-type triterpene glycoside from the sea cucumber Holothuria hilla
    Jun Wu
    Research Center for Marine Drugs, College of Pharmacy, Second Military Medical University, 325 Guo He Road, Shanghai, 200433, P R China
    Chem Biodivers 3:1249-54. 2006
    A new triterpene glycoside, hillaside C (1), was isolated from the sea cucumber Holothuria hilla Lesson, which is found in the South China Sea, and its structure has been elucidated by spectral analysis (ESI-MS and NMR) and chemical ..
  76. ncbi Indigenous community-based fisheries in Australia
    Jennifer Carter
    Department of Environmental and Planning Studies, Faculty of Arts and Social Sciences, University of the Sunshine Coast, Maroochydore DC, 4556 QLD, Australia
    J Environ Manage 85:866-75. 2007
    The commercial sea cucumber species known as Sandfish (Holothuria scabra) occurs intertidally and subtidally in the Northern Territory of Australia, on or adjacent to Aboriginal land...
  77. ncbi Constituents of Holothuroidea, 18. Isolation and structure of biologically active disialo- and trisialo-gangliosides from the sea cucumber Cucumaria echinata
    Fumiaki Kisa
    Faculty of Pharmaceutical Sciences, Kyushu University, 3 1 1 Maidashi, Fukuoka 812 8582, Japan
    Chem Pharm Bull (Tokyo) 54:1293-8. 2006
    ..These gangliosides showed neuritogenic activity toward the rat pheochromocytoma cell line PC-12 in the presence of nerve growth factor...
  78. ncbi Constituents of holothuroidea, 16. Determination of Absolute configuration of the branched methyl group in ante-iso type side chain moiety on long chain base of glucocerebroside from the sea cucumber Holothuria leucospilota
    Koji Yamada
    Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan
    Chem Pharm Bull (Tokyo) 53:1333-4. 2005
    ..side chain moiety on the long chain base of glucocerebroside, HLC-2-A, which was isolated from the sea cucumber Holothuria leucospilota was determined...
  79. ncbi In vitro decondensation of the sperm chromatin in Holothuria tubulosa (sea cucumber) not affecting proteolysis of basic nuclear proteins
    Luis J Del Valle
    Center de Biotecnología Molecular, Departament d Enginyeria Quimica, EUETIB, Consorci Escola Industrial de Barcelona, Universitat Politecnica de Catalunya, 08036 Barcelona, Spain
    Dev Growth Differ 47:333-42. 2005
    ..We have studied the presence of this proteolytic activity in Holothuria tubulosa (sea cucumber) and its possible relationship with sperm nuclei decondensation...
  80. ncbi Symbionts of holothurians from south Vietnam: intra- and interspecific interactions
    S A Lyskin
    Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences, Leninskii pr 33, Moscow, 119071, Russia
    Dokl Biol Sci 401:116-9. 2005
  81. ncbi Constituents of Holothuroidea, 15. Isolation of ante-iso type regio-isomer on long chain base moiety of glucocerebroside from the sea cucumber Holothuria leucospilota
    Koji Yamada
    Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan
    Chem Pharm Bull (Tokyo) 53:788-91. 2005
    ..and ante-iso isomers, from the less polar lipid fraction of a chloroform/methanol extract of the sea cucumber Holothuria leucospilota...
  82. ncbi A simple enzymatic method for examining calcite ossicles of Echinodermata
    C G Tiago
    Centro de Biologia Marinha, Universidade de Sao Paulo, São Sebastião, Brazil
    J Microsc 218:240-6. 2005
    ..method was tested on fragments of body tissues from three species in three different orders of holothurians: Holothuria grisea Selenka, 1867 (Aspidochirotida), Duasmodactyla seguroensis (Deichmann, 1930) (Dendrochirotida) and ..
  83. ncbi Holothurins B(2), B(3), and B(4), new triterpene glycosides from mediterranean sea cucumbers of the genus holothuria
    Alexandra S Silchenko
    Pacific Institute of Bioorganic Chemistry, Far East Branch of the Russian Academy of Sciences, 690022 Vladivostok, Russian Federation
    J Nat Prod 68:564-7. 2005
    Triterpene glycosides of three species of the Mediterranean sea cucumbers Holothuria polii, Holothuria tubulosa, and Holothuria sp. were studied...
  84. ncbi [Clinical study on the antithrombotic effects of Holothuria ldeucospilota acidic mucopolysaccharide]
    X Wang
    Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025
    Zhonghua Xue Ye Xue Za Zhi 18:457-9. 1997
    To study the antithrombotic effects of Holothuria Ldeucospilota Acidic Mucopolysaccharide (HLAM).
  85. ncbi Gene flow and population history in high dispersal marine invertebrates: mitochondrial DNA analysis of Holothuria nobilis (Echinodermata: Holothuroidea) populations from the Indo-Pacific
    S Uthicke
    Australian Institute of Marine Science, PMB No 3, Townsville, Queensland 4810, Australia
    Mol Ecol 12:2635-48. 2003
    The sea cucumber, Holothuria nobilis, has a long-lived planktotrophic larvae, and previous allozyme surveys have suggested that high dispersal is realized. In contrast, recent ecological studies indicate that dispersal is low...
  86. ncbi An annotated description of shallow water holothurians (Echinodermata: Holothuroidea) from Cayos Cochinos, Honduras
    Carlos Roberto Hasbún
    Dept of Biological Sciences, University of Hull, Kingston upon Hull, HU6 7RX, UK
    Rev Biol Trop 50:669-78. 2002
    ..to a single order (Aspidochirotida) and two families: Stichopodidae (Isostichopus badionotus) and Holothuriidae (Holothuria mexicana, H. thomasi, H. arenicola and Actinopyga agassizi)...
  87. ncbi Regeneration of the enteric nervous system in the sea cucumber Holothuria glaberrima
    J E Garcia-Arraras
    Department of Biology, University of Puerto Rico, Rio Piedras Campus, 00931, USA
    J Comp Neurol 406:461-75. 1999
    ..and ultrastructural studies to describe the regeneration of the enteric nervous system in the sea cucumber Holothuria glaberrima...
  88. ncbi Identification of the novel 7-methyl-6-octadecenoic acid in Holothuria mexicana
    N M Carballeira
    Department of Chemistry, University of Puerto Rico, San Juan, Puerto Rico 00931
    J Nat Prod 59:1076-8. 1996
    The phospholipid fatty acid composition of Holothuria mexicana was investigated, and the novel 7-methyl-6-octadecenoic acid was identified...
  89. ncbi Galanin-like immunoreactivity in the sea cucumber Holothuria glaberrima
    L Díaz-Miranda
    Department of Biology, University of Puerto Rico, Rio Piedras Campus, Rio Piedras, P R 00931, Puerto Rico
    Cell Tissue Res 286:385-91. 1996
    ..In this study, galanin-like immunoreactivity was detected in an invertebrate, the sea cucumber Holothuria glaberrima...
  90. ncbi Ontogeny of the holothurian larval nervous system: evolution of larval forms
    Cory D Bishop
    Kewalo Marine Laboratory, University of Hawaii, Honolulu, HI, USA
    Dev Genes Evol 217:585-92. 2007
    ..apomorphic features, we have examined the ontogeny of the dipleurula-like auricularia larva of the sea cucumber, Holothuria atra...
  91. pmc Qualitative and quantitative saponin contents in five sea cucumbers from the Indian ocean
    Séverine Van Dyck
    Marine Biology Laboratory, University of Mons, 20 Place du Parc, B 7000 Mons, Belgium
    Mar Drugs 8:173-89. 2010
    ..The smallest number of saponins was observed in Holothuria atra, which contained a total of four congeners, followed by Holothuria leucospilota, Pearsonothuria graeffei ..
  92. ncbi The effect of sea cucumber Holothuria tubulosa (G., 1788) on nutrient and sediment of Aegean Sea shores
    Dilek Işgören Emiroğlu
    Department of Aquaculture, Faculty of Fisheries, Ege University, 35100 Bornova, Izmir, Turkiye
    Pak J Biol Sci 10:586-9. 2007
    The effects of sea cucumber, Holothuria tubulosa, on sediment of hypereutrophic conditions were investigated. Research was designed as two groups with 3 replicates...
  93. ncbi Regulation of sperm flagellar motility activation and chemotaxis caused by egg-derived substance(s) in sea cucumber
    Masaya Morita
    Tropical Biosphere Research Center, Sesoko Station, University of the Ryukyus, Sesoko, Motobu, Okinawa, Japan
    Cell Motil Cytoskeleton 66:202-14. 2009
    The sea cucumber Holothuria atra is a broadcast spawner. Among broadcast spawners, fertilization occurs by means of an egg-derived substance(s) that induces sperm flagellar motility activation and chemotaxis...
  94. ncbi A first total synthesis of ganglioside HLG-2
    Yuki Iwayama
    Department of Applied Bioorganic Chemistry, Faculty of Applied Biological Sciences, Gifu University, 1 1 Yanagido, Gifu shi, Gifu, Japan
    Chemistry 15:4637-48. 2009
    ..A first synthesis of the neuritegenic ganglioside HLG-2, which was identified in extracts of the sea cucumber Holothuria leucospilota, is described...
  95. pmc A comparison between two brine shrimp assays to detect in vitro cytotoxicity in marine natural products
    José Luis Carballo
    Instituto de Ciencias del Mar y Limnologia, UNAM, Estación Mazatlán, Apartado Postal 811, Mazatlan 82000, Mexico
    BMC Biotechnol 2:17. 2002
    ..However, we think that it is necessary to evaluate the suitability of the brine shrimp methods before they are used as a general bio-assay to test natural marine products for pharmacological activity...
  96. pmc Gene expression profiling of intestinal regeneration in the sea cucumber
    Pablo A Ortiz-Pineda
    University of Puerto Rico, Rio Piedras, Department of Biology, San Juan, PR, USA
    BMC Genomics 10:262. 2009
    ..For the last decade, our laboratory has been using the sea cucumber Holothuria glaberrima to dissect the cellular and molecular events that allow for such amazing regenerative processes...
  97. ncbi Bioactivity as an options value of sea cucumbers in the Egyptian Red Sea
    A J Lawrence
    Department of Life Sciences, University of the West Indies, St Augustine, Trinidad and Tobago
    Conserv Biol 24:217-25. 2010
    ..All habitat types were surveyed within these regions. We found 22 species of sea cucumber of which two, Holothuria fuscogilva and Holothuria flavomaculata, were recorded in Egypt for the first time...
  98. ncbi Antifungal active triterpene glycosides from sea cucumber Holothuria scabra
    Hua Han
    Research Center for Marine Drugs, School of Pharmacy, Second Military Medical University, Shanghai 200433, China
    Yao Xue Xue Bao 44:620-4. 2009
    To study the new antifungal active triterpene glycosides of sea cucumber Holothuria scabra...
  99. ncbi Euzebya tangerina gen. nov., sp. nov., a deeply branching marine actinobacterium isolated from the sea cucumber Holothuria edulis, and proposal of Euzebyaceae fam. nov., Euzebyales ord. nov. and Nitriliruptoridae subclassis nov
    Midori Kurahashi
    Institute of Molecular and Cellular Biosciences, The University of Tokyo, Bunkyo ku, Tokyo 113 0032, Japan
    Int J Syst Evol Microbiol 60:2314-9. 2010
    ..actinobacterial strain, designated F10(T), was isolated from the abdominal epidermis of a sea cucumber, Holothuria edulis, collected in seawater off the coast of Japan...
  100. ncbi Elucidation of molecular diversity and body distribution of saponins in the sea cucumber Holothuria forskali (Echinodermata) by mass spectrometry
    Séverine Van Dyck
    Marine Biology Laboratory, University of Mons Hainaut, Mons, Belgium
    Comp Biochem Physiol B Biochem Mol Biol 152:124-34. 2009
    ..We investigated the complex saponin mixture extracted from the common Mediterranean species Holothuria forskali...
  101. ncbi [Complexation between triterpene glycosides of holothurians and cholesterol is the basis of lipid-saponin carriers of subunit protein antigens]
    A N Mazeĭka
    Biofizika 53:826-35. 2008
    ..Thus, the possibility of the formation of a new type of antigen carries on the basis of marine triterpene glycosides was proved...

Research Grants1

  1. Nervous system regeneration, molecular basis in echinoderms
    JOSE E GARCIA-ARRARAS; Fiscal Year: 2013
    ..We have pioneered the use of a novel model system to study nervous system regeneration, The echinoderm Holothuria glaberrima...