Genomes and Genes
Summary: A large order of insects comprising the butterflies and moths.
Publications335 found, 100 shown here
- Toward reconstructing the evolution of advanced moths and butterflies (Lepidoptera: Ditrysia): an initial molecular studyJerome C Regier
Center for Biosystems Research, University of Maryland Biotechnology Institute, College Park, 20742, USA
BMC Evol Biol 9:280. 2009In the mega-diverse insect order Lepidoptera (butterflies and moths; 165,000 described species), deeper relationships are little understood within the clade Ditrysia, to which 98% of the species belong...
- RNA interference in Lepidoptera: an overview of successful and unsuccessful studies and implications for experimental designOlle Terenius
Department of Ecology, Swedish University of Agricultural Sciences, Uppsala, Sweden
J Insect Physiol 57:231-45. 2011..However, in Lepidoptera (moths and butterflies) RNAi has many times proven to be difficult to achieve...
- Galleria mellonella as a model system for studying Listeria pathogenesisKrishnendu Mukherjee
Institute for Phytopathology and Applied Zoology, Justus Liebig University, Frankfurter Strasse 107, 35392 Giessen, Germany
Appl Environ Microbiol 76:310-7. 2010..isolated from a wide variety of settings from both the clinic and the environment...
- Extreme diversity of tropical parasitoid wasps exposed by iterative integration of natural history, DNA barcoding, morphology, and collectionsM Alex Smith
The Biodiversity Institute of Ontario, University of Guelph, Guelph Ontario, N1G 2W1 Canada
Proc Natl Acad Sci U S A 105:12359-64. 2008....
- Biochemistry and genetics of insect resistance to Bacillus thuringiensisJuan Ferré
Department of Genetics, University of Valencia, 46110 Burjassot Valencia, Spain
Annu Rev Entomol 47:501-33. 2002..The understanding of the biochemical and genetic basis of resistance to Bt can help design appropriate management tactics to delay or reduce the evolution of resistance in insect populations...
- Allopatry as a gordian knot for taxonomists: patterns of DNA barcode divergence in arctic-alpine lepidopteraMarko Mutanen
Zoological Museum, Department of Biology, University of Oulu, Oulu, Finland
PLoS ONE 7:e47214. 2012..on the levels and patterns of sequence divergence among populations of 122 arctic-alpine species of Lepidoptera from the Alps, Fennoscandia and North America...
- DNA barcoding the geometrid fauna of Bavaria (Lepidoptera): successes, surprises, and questionsAxel Hausmann
Entomology Department, Zoological Collection of the State of Bavaria, Munich, Germany
PLoS ONE 6:e17134. 2011..The present study provides a comprehensive DNA barcode library for the Geometridae, one of the most diverse of insect families...
- Mitochondrial genome sequence and expression profiling for the legume pod borer Maruca vitrata (Lepidoptera: Crambidae)Venu M Margam
Department of Entomology, Purdue University, West Lafayette, Indiana, United States of America
PLoS ONE 6:e16444. 2011..14,054 bp near complete sequencing of the mitochondrial genome of the legume pod borer (LPB), Maruca vitrata (Lepidoptera: Crambidae), which we subsequently used to estimate divergence and relationships within the lepidopteran ..
- Census of the bacterial community of the gypsy moth larval midgut by using culturing and culture-independent methodsNichole A Broderick
Department of Entomology, University of Wisconsin, Madison, Wisconsin 53706, USA
Appl Environ Microbiol 70:293-300. 2004Little is known about bacteria associated with Lepidoptera, the large group of mostly phytophagous insects comprising the moths and butterflies...
- Can deliberately incomplete gene sample augmentation improve a phylogeny estimate for the advanced moths and butterflies (Hexapoda: Lepidoptera)?Soowon Cho
Department of Entomology, University of Maryland, College Park, MD 20742, USA
Syst Biol 60:782-96. 2011..poorly understood deeper relationships in the large clade Ditrysia ( > 150,000 species) of the insect order Lepidoptera (butterflies and moths)...
- Parallel evolution of Bacillus thuringiensis toxin resistance in lepidopteraSimon W Baxter
Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, United Kingdom
Genetics 189:675-9. 2011..Here we report genetic mapping of a membrane transporter (ABCC2) to a locus controlling Bt Cry1Ac toxin resistance in two lepidopterans, implying that this protein plays a critical role in Bt function...
- The complete mitochondrial genome of Spilonota lechriaspis Meyrick (Lepidoptera: Tortricidae)Jin Liang Zhao
Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, 210046, China
Mol Biol Rep 38:3757-64. 2011We determined the nucleotide sequence of the mitochondrial genome (mtgenome) of Spilonota lechriaspis Meyrick (Lepidoptera: Tortricidae)...
- Structural characteristics and phylogenetic analysis of the mitochondrial genome of the sugarcane borer, Diatraea saccharalis (Lepidoptera: Crambidae)Weiwei Li
Sichuan Key Laboratory of Conservation Biology on Endangered Wildlife, College of Life Sciences, Sichuan University, Chengdu, PR China
DNA Cell Biol 30:3-8. 2011..The complete mitochondrial sequences of D. saccharalis reported in this study can provide useful data in analyzing divergence of lepidopteran insects and in developing DNA-based diagnoses and genetic makers...
- DNA barcodes for 1/1000 of the animal kingdomPaul D N Hebert
Biodiversity Institute of Ontario, University of Guelph, Guelph, Ontario, Canada, N1G 2W1
Biol Lett 6:359-62. 2010This study reports DNA barcodes for more than 1300 Lepidoptera species from the eastern half of North America, establishing that 99.3 per cent of these species possess diagnostic barcode sequences...
- Candidate chemosensory ionotropic receptors in a LepidopteraV Olivier
INRA, UMR 1272 INRA UPMC PISC Physiologie de l Insecte Signalisation et Communication, Route de Saint Cyr, Versailles, France
Insect Mol Biol 20:189-99. 2011..Our data suggest that we identified members of the insect IR chemosensory receptor family in S. littoralis and we report here the first demonstration of IR expression in Lepidoptera.
- Virulence of serotype M3 Group A Streptococcus strains in wax worms (Galleria mellonella larvae)Randall J Olsen
The Methodist Hospital Research Institute, Houston, TX, USA
Virulence 2:111-9. 2011..We conclude that GAS virulence in wax worms strongly correlates with the data obtained in vertebrate models, and thus, the Galleria mellonella larva is a useful host organism to study GAS pathogenesis...
- A mechanism of cell death involving an adenylyl cyclase/PKA signaling pathway is induced by the Cry1Ab toxin of Bacillus thuringiensisXuebin Zhang
Biological Targets Inc, Dallas, TX 75235, USA
Proc Natl Acad Sci U S A 103:9897-902. 2006..The discovery of a toxin-induced cell death pathway specifically linked to BT-R(1) in insect cells should provide insights into how insects evolve resistance to Bt and into the development of new, safer insecticides...
- DNA barcodes distinguish species of tropical LepidopteraMehrdad Hajibabaei
Department of Integrative Biology, University of Guelph, Guelph, ON, Canada N1G 2W1
Proc Natl Acad Sci U S A 103:968-71. 2006..Here we show that cytochrome c oxidase I DNA barcodes effectively discriminate among species in three Lepidoptera families from Area de Conservación Guanacaste in northwestern Costa Rica. We found that 97...
- Renewable and nonrenewable resources: amino acid turnover and allocation to reproduction in LepidopteraDiane M O'Brien
Center for Conservation Biology, Department of Biological Sciences, 371 Serra Mall, Stanford University, Stanford, CA 94305 5020, USA
Proc Natl Acad Sci U S A 99:4413-8. 2002..This study demonstrates that female Lepidoptera can synthesize a large fraction of egg amino acids from nectar sugars, using endogenous sources of nitrogen...
- Large-scale evolutionary patterns of host plant associations in the LepidopteraSteph B J Menken
Institute for Biodiversity and Ecosystem Dynamics, Section Evolutionary Biology, University of Amsterdam, Kruislaan 318, 1098 SM Amsterdam, The Netherlands
Evolution 64:1098-119. 2010We characterized evolutionary patterns of host plant use across about 2500 species of British Lepidoptera, using character optimization and independent phylogenetic contrasts among 95 operational taxa, and evaluated the extent to which ..
- Transcriptome sequencing, and rapid development and application of SNP markers for the legume pod borer Maruca vitrata (Lepidoptera: Crambidae)Venu M Margam
Department of Entomology, Purdue University, West Lafayette, Indiana, United States of America
PLoS ONE 6:e21388. 2011The legume pod borer, Maruca vitrata (Lepidoptera: Crambidae), is an insect pest species of crops grown by subsistence farmers in tropical regions of Africa...
- The complete mitochondrial genome of the fall webworm, Hyphantria cunea (Lepidoptera: Arctiidae)Fang Liao
1 College of Life Sciences, Nankai University, Tianjin 300071, China
Int J Biol Sci 6:172-86. 2010The complete mitochondrial genome (mitogenome) of the fall webworm, Hyphantria cunea (Lepidoptera: Arctiidae) was determined. The genome is a circular molecule 15 481 bp long...
- Polydnavirus genomes reflect their dual roles as mutualists and pathogensBruce A Webb
Department of Entomology, University of Kentucky, Lexington, KY 40506, USA
Virology 347:160-74. 2006....
- Changes of inheritance mode and fitness in Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae) along with its resistance evolution to Cry1Ac toxinGe Mei Liang
State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100094, China
J Invertebr Pathol 97:142-9. 2008..79, 0.64 and 0.59 in their respective BtR-F(16), BtR-F(34) and BtR-F(87) strains...
- The differential effects of herbivory by first and fourth instars of Trichoplusia ni (Lepidoptera: Noctuidae) on photosynthesis in Arabidopsis thalianaJennie Y Tang
Department of Plant Biology, University of Illinois at Urbana Champaign, 265 Morrill Hall, 505 S Goodwin Ave, Urbana, IL 61801 3707, USA
J Exp Bot 57:527-36. 2006..The mode of feeding by different instars of T. ni determined the photosynthetic response to herbivory, which appeared to be mediated by the level of water stress associated with herbivore damage...
- The complete mitochondrial genome of the yellow coaster, Acraea issoria (Lepidoptera: Nymphalidae: Heliconiinae: Acraeini): sequence, gene organization and a unique tRNA translocation eventJing Hu
College of Life Sciences, Anhui Normal University, Wuhu, 241000, China
Mol Biol Rep 37:3431-8. 2010In this paper, the complete mitochondrial genome of Acraea issoria (Lepidoptera: Nymphalidae: Heliconiinae: Acraeini) is reported; a circular molecule of 15,245 bp in size. For A...
- Mitochondrial DNA analysis of field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) and of its relationship to H. zeaGajanan T Behere
Centre for Environmental Stress and Adaptation Research, Department of Genetics, Bio21 Institute of Molecular Science and Biotechnology, The University of Melbourne, Parkville, Australia
BMC Evol Biol 7:117. 2007..armigera has been doubted, due to its wide distribution and plant host range across the Old World. This study explores the global genetic diversity of H. armigera and its evolutionary relationship to H zea...
- Immunity or digestion: glucanase activity in a glucan-binding protein family from LepidopteraYannick Pauchet
Department of Entomology, Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans Knoell Str 8, 07745 Jena, Germany
J Biol Chem 284:2214-24. 2009..Homologs of this predominantly midgut-expressed gene from many Lepidoptera possess key residues shown to be part of the active site of other glucanases, and form a cluster that is ..
- The genome sequence and evolution of baculovirusesElisabeth A Herniou
Department of Biological Sciences, Imperial College of Science, Technology and Medicine, London SW7 2AZ, United Kingdom
Annu Rev Entomol 48:211-34. 2003..Examination of gene order conservation revealed a core gene cluster of four genes, helicase, lef-5, ac96, and 38K(ac98), whose relative positions are conserved in all baculovirus genomes...
- Genomic outposts serve the phylogenomic pioneers: designing novel nuclear markers for genomic DNA extractions of lepidopteraNiklas Wahlberg
Department of Zoology, Stockholm University, Stockholm, Sweden
Syst Biol 57:231-42. 2008..We test this approach on Lepidoptera, searching the draft genomic sequence of the silk moth Bombyx mori, for exons > 500 bp in length, removing ..
- Genome of the most widely used viral biopesticide: Anticarsia gemmatalis multiple nucleopolyhedrovirusJuliana Velasco de Castro Oliveira
Laboratório de Evolução Molecular e Bionformática, Departamento de Microbiologia, Instituto de Ciencias Biomedicas, Universidade de Sao Paulo, SP, Brazil
J Gen Virol 87:3233-50. 2006..fumiferana MNPV), sharing eight defining genes, and the Autographa californica MNPV (AcMNPV) lineage (AcMNPV, Rachiplusia ou NPV and Bombyx mori NPV), sharing nine defining genes...
- Sequestration of defensive substances from plants by LepidopteraRitsuo Nishida
Laboratory of Chemical Ecology, Graduate School of Agriculture, Kyoto University, Kyoto 606 8502, Japan
Annu Rev Entomol 47:57-92. 2002..This review illustrates the biochemical, physiological, and ecological characteristics of phytochemical-based defense systems that can shed light on the evolution of the widely developed sequestering lifestyles among the Lepidoptera.
- Characterization of the complete mitochondrial genomes of Cnaphalocrocis medinalis and Chilo suppressalis (Lepidoptera: Pyralidae)Huan Na Chai
Institute of Applied Entomology, Yangzhou University, Yangzhou 225009, China
Int J Biol Sci 8:561-79. 2012The complete mitochondrial genomes (mitogenomes) of Cnaphalocrocis medinalis and Chilo suppressalis (Lepidoptera: Pyralidae) were determined and analyzed. The circular genomes were 15,388 bp long for C. medinalis and 15,395 bp long for C...
- Galleria mellonella as a model host to study infection by the Francisella tularensis live vaccine strainGeorge Aperis
Division of Infectious Diseases, Massachusetts General Hospital, Gray Jackson 504, 55 Fruit Street, Boston, MA 02114, USA
Microbes Infect 9:729-34. 2007We used the killing of Galleria mellonella (Lepidoptera: Pyralidae; the greater wax moth) caterpillar by the live vaccine strain (LVS) of Francisella tularensis to develop an invertebrate host system that can be used to study F...
- Sex chromosomes and sex determination in LepidopteraW Traut
Universitat Lubeck, Zentrum fur Medizinische Strukturbiologie, Institut fur Biologie, Lubeck, Germany
Sex Dev 1:332-46. 2007The speciose insect order Lepidoptera (moths and butterflies) and their closest relatives, Trichoptera (caddis flies), share a female-heterogametic sex chromosome system...
- Barcoding lepidoptera: current situation and perspectives on the usefulness of a contentious techniqueKarina L Silva-Brandão
Depto de Entomologia e Acarologia, Escola Superior de Agricultura Luiz de Queiroz, Univ de São Paulo, Piracicaba, SP
Neotrop Entomol 38:441-51. 2009..For insects of the order Lepidoptera neither side seems totally correct or wrong, and although many groups of lepidopterans have been taxonomically ..
- Survey of a salivary effector in caterpillars: glucose oxidase variation and correlation with host rangeHerb Eichenseer
Pioneeer Hi Bred International Crop Genetics Research and Development, Johnston, IA 50131, USA
J Chem Ecol 36:885-97. 2010..In this study, we examined the labial gland GOX activities in 23 families of Lepidoptera (85 species) and two families of plant-feeding Hymenoptera (three species)...
- The complete nucleotide sequence of the mitochondrial genome of the cabbage butterfly, Artogeia melete (Lepidoptera: Pieridae)Guiyun Hong
Department of Biotechnology, Hefei University of Technology, Hefei 230009, China
Acta Biochim Biophys Sin (Shanghai) 41:446-55. 2009..The gene order of A. melete mitogenome is typical of Lepidoptera and differs from the insect ancestral type in the location of trnM. The A...
- Identification of receptors of main sex-pheromone components of three Lepidopteran speciesHidefumi Mitsuno
Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan
Eur J Neurosci 28:893-902. 2008....
- A gene-based linkage map for Bicyclus anynana butterflies allows for a comprehensive analysis of synteny with the lepidopteran reference genomePatricia Beldade
Institute of Biology, Leiden University, Leiden, The Netherlands
PLoS Genet 5:e1000366. 2009..This is discussed in relation to the identification of the loci contributing to color pattern evolution in butterflies...
- Phylogeography and genetic diversity of a widespread Old World butterfly, Lampides boeticus (Lepidoptera: Lycaenidae)David J Lohman
Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, Singapore 117543, Republic of Singapore
BMC Evol Biol 8:301. 2008..With a distribution on four continents ranging throughout most of the Old World, Lampides boeticus (Lepidoptera: Lycaenidae) is one of the most widely distributed species of butterfly...
- Contributions of gut bacteria to Bacillus thuringiensis-induced mortality vary across a range of LepidopteraNichole A Broderick
Department of Entomology, University of Wisconsin, Madison, WI 53706, USA
BMC Biol 7:11. 2009..thuringiensis strain, and environment affect the wide range of susceptibilities among Lepidoptera, but the interaction of gut bacteria with these factors is not understood...
- Bitter gourd proteinase inhibitors: potential growth inhibitors of Helicoverpa armigera and Spodoptera lituraManasi Telang
Plant Molecular Biology Unit, Division of Biochemical Sciences, National Chemical Laboratory, Pune 411 008, India
Phytochemistry 63:643-52. 2003..armigera and S. litura. The results advocate use of BGPIs to introduce insect resistance in otherwise susceptible plants...
- A molecular phylogeny for yponomeutoidea (insecta, Lepidoptera, ditrysia) and its implications for classification, biogeography and the evolution of host plant useJae Cheon Sohn
Department of Entomology, University of Maryland, College Park, MD, USA
PLoS ONE 8:e55066. 2013Yponomeutoidea, one of the early-diverging lineages of ditrysian Lepidoptera, comprise about 1,800 species worldwide, including notable pests and insect-plant interaction models...
- Sialome of a generalist lepidopteran herbivore: identification of transcripts and proteins from Helicoverpa armigera labial salivary glandsMaria de la Paz Celorio-Mancera
Department of Entomology, Max Planck Institute for Chemical Ecology, Jena, Germany
PLoS ONE 6:e26676. 2011..This identification of secreted salivary gland proteins allows a more comprehensive understanding of insect feeding and poses new challenges for the elucidation of protein function...
- Pre-exposure of Galleria mellonella larvae to different doses of Aspergillus fumigatus conidia causes differential activation of cellular and humoral immune responsesJohn P Fallon
Medical Mycology Unit, Department of Biology, National Institute for Cellular Biotechnology, National University of Ireland, Maynooth, Ireland
Virulence 2:413-21. 2011....
- Mobilizing the genome of Lepidoptera through novel sequence gains and end creation by non-autonomous Lep1 HelitronsBrad S Coates
1USDA ARS, Corn Insect and Crop Genetics Research Unit, 113 Genetics Laboratory, Iowa State University, Ames, IA 50011, USA
DNA Res 19:11-21. 2012..These findings are important in understanding the structural requirements of genomic DNA sequences that are acquired and transposed by Helitron-like TEs...
- Complexity and variability of gut commensal microbiota in polyphagous lepidopteran larvaeXiaoshu Tang
Department of Bioorganic Chemistry, Max Planck Institute for Chemical Ecology, Jena, Germany
PLoS ONE 7:e36978. 2012..However, the complexity, dynamics and types of interactions between the insect hosts and their gut microbiota are far from being well understood...
- Insecticide resistance in populations of the diamondback moth, Plutella xylostella (L.) (Lepidoptera: Plutellidae), from the state of Pernambuco, BrazilV C Santos
Depto de Agronomia Entomologia, Univ Federal Rural de Pernambuco, Recife, PE, Brasil
Neotrop Entomol 40:264-70. 2011..These results indicated that control failures were associated with resistance by some of the evaluated insecticides, reinforcing the need for resistance management in areas of the state of Pernambuco...
- Oral Candida albicans isolates from HIV-positive individuals have similar in vitro biofilm-forming ability and pathogenicity as invasive Candida isolatesJuliana C Junqueira
Department of Biosciences and Oral Diagnosis, Univ Estadual Paulista UNESP, Eng, Francisco José Longo, Sao Jose dos Campos, Brazil
BMC Microbiol 11:247. 2011..We assessed the pathogenicity of the strains by infecting G. mellonella animals with Candida strains and observing survival...
- Complete mitochondrial genome of Kallima inachus (Lepidoptera: Nymphalidae: Nymphalinae): comparison of K. inachus and Argynnis hyperbiusXin Min Qin
College of Life Science, Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection Guangxi Normal University, Ministry of Education, Guilin, Guangxi 541004, PR China
Mitochondrial DNA 23:318-20. 2012In this paper, we sequenced the complete mitochondrial genome of Kallima inachus (Lepidoptera: Nymphalidae: Nymphalinae), which is considered a rare species in China. The genome is 15,183 bp in size...
- The complete mitochondrial genomes of two ghost moths, Thitarodes renzhiensis and Thitarodes yunnanensis: the ancestral gene arrangement in LepidopteraYong Qiang Cao
Key Laboratory of Tropical Forest Ecology, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Kunming, China
BMC Genomics 13:276. 2012b>Lepidoptera encompasses more than 160,000 described species that have been classified into 45-48 superfamilies...
- Field evolved resistance in Helicoverpa armigera (Lepidoptera: Noctuidae) to Bacillus thuringiensis toxin Cry1Ac in PakistanAnwaar H K Alvi
Department of Entomology, PMAS Arid Agriculture University, Rawalpindi, Pakistan
PLoS ONE 7:e47309. 2012..Resistance to Cry1Ac was probably due to a single but unstable factor suggesting that crop rotation with non-Bt cotton or other crops could reduce the selection pressure for H. armigera and improve the sustainability of Bt cotton...
- Three cadherin alleles associated with resistance to Bacillus thuringiensis in pink bollwormShai Morin
Department of Entomology, University of Arizona, Tucson, AZ 85721, USA
Proc Natl Acad Sci U S A 100:5004-9. 2003..Together with previous evidence, the results reported here identify the cadherin gene as a leading target for DNA-based screening of resistance to Bt crops in lepidopteran pests...
- Major putative pesticide receptors, detoxification enzymes, and transcriptional profile of the midgut of the tobacco budworm, Heliothis virescens (Lepidoptera: Noctuidae)Yu Cheng Zhu
USDA ARS JWDSRC, Stoneville, MS 38776, USA
J Invertebr Pathol 106:296-307. 2011..Future development resistance management strategies could benefit from this study and help continue research to identify key genes targetable by classic and novel approaches...
- Development, survival and fitness performance of Helicoverpa zea (Lepidoptera: Noctuidae) in MON810 Bt field cornT A Horner
USDA, APHIS, PPQ, 4700 River Road, Unit 133, Riverdale, MD 20737, USA
J Econ Entomol 96:914-24. 2003..zea populations. Implications of localized population suppression are discussed...
- Transcriptomic profiling of Microplitis demolitor bracovirus reveals host, tissue and stage-specific patterns of activityKavita Bitra
Department of Entomology, University of Georgia, Athens, GA 30602, USA
J Gen Virol 92:2060-71. 2011..demolitor, albeit at much lower levels than in P. includens. However, another encapsidated gene (orph-B1) was expressed in adult M. demolitor at similar levels to those detected in P. includens...
- Physiological significance of alternatively spliced exon combinations of the single-copy gene class A chitin synthase in the insect Ostrinia furnacalis (Lepidoptera)M Qu
School of Bioscience and Biotechnology, Dalian University of Technology, Dalian, China
Insect Mol Biol 21:395-404. 2012..Spliced exons 2a and 2b have also been observed in Bombyx mori; therefore, this work provides new insights into the regulation of insect chitin synthase, particularly in lepidopteran insects...
- Towards a global barcode library for Lymantria (Lepidoptera: Lymantriinae) tussock moths of biosecurity concernJeremy R deWaard
Forest Sciences, University of British Columbia, Vancouver, British Columbia, Canada
PLoS ONE 5:e14280. 2010....
- Mitochondrial genome of the cotton bollworm Helicoverpa armigera (Lepidoptera: Noctuidae) and comparison with other LepidopteransJiao Yin
State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, People s Republic of China
Mitochondrial DNA 21:160-9. 2010..The H. armigera A+T-rich region contains a conserved structure combining the motif ATAGA and a 19-bp poly-T stretch, but absence of the 9-bp poly-A element upstream of trnM...
- Simultaneous feeding by aboveground and belowground herbivores attenuates plant-mediated attraction of their respective natural enemiesSergio Rasmann
Evolutionary Entomology, Institute of Zoology, University of Neuchatel, Rue Emile Argand 11, CP 158, CH 2009 Neuchatel, Switzerland
Ecol Lett 10:926-36. 2007..This first study to measure effects of belowground herbivory on aboveground tritrophic signalling and vice-versa reemphasizes the important role of plants in bridging interactions between spatially distinct components of the ecosystem...
- Complete nucleotide sequence and organization of the mitogenome of the red-spotted apollo butterfly, Parnassius bremeri (Lepidoptera: Papilionidae) and comparison with other lepidopteran insectsMan Il Kim
College of Agriculture and Life Sciences, Chonnam National University, Gwangju 500 757, Korea
Mol Cells 28:347-63. 2009The 15,389-bp long complete mitogenome of the endangered red-spotted apollo butterfly, Parnassius bremeri (Lepidoptera: Papilionidae) was determined in this study...
- Repetitive genome elements in a European corn borer, Ostrinia nubilalis, bacterial artificial chromosome library were indicated by bacterial artificial chromosome end sequencing and development of sequence tag site markers: implications for lepidopteran gBrad S Coates
USDA ARS, Corn Insects and Crop Genetics Research Unit, Genetics Laboratory, Iowa State University, Ames, IA 50011, USA
Genome 52:57-67. 2009..Single-locus sequence tag site markers described here have downstream application for integration within linkage maps and comparative genomic studies...
- Oligopeptide permease is required for expression of the Bacillus thuringiensis plcR regulon and for virulenceM Gominet
, CNRS (URA2172, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex, France
Mol Microbiol 40:963-75. 2001..subtilis. However, analysis of plcR expression in DeltaoppB, Deltaspo0A and DeltaoppB Deltaspo0A mutants indicates that Opp is required for plcR expression via a Spo0A-independent mechanism...
- Key biosynthetic gene subfamily recruited for pheromone production prior to the extensive radiation of LepidopteraMarjorie A Liénard
Chemical Ecology and Ecotoxicology, Department of Ecology, Lund University, Ecology Building, SE 22362, Lund, Sweden
BMC Evol Biol 8:270. 2008..of these compounds and to a large extent they account for the great diversity of pheromone structures in Lepidoptera. A novel desaturase gene subfamily that displays Delta11 catalytic activities has been highlighted to account ..
- A maize (E)-beta-caryophyllene synthase implicated in indirect defense responses against herbivores is not expressed in most American maize varietiesTobias G Köllner
Max Planck Institute for Chemical Ecology, D 07745 Jena, Germany
Plant Cell 20:482-94. 2008..We argue that the (E)-beta-caryophyllene defense signal was lost during breeding of the North American lines and that its restoration might help to increase the resistance of these lines against agronomically important pests...
- The complete nucleotide sequence of the mitochondrial genome of Phthonandria atrilineata (Lepidoptera: Geometridae)Ling Yang
School of Life Sciences, University of Science and Technology of China, Hefei, 230027, People s Republic of China
Mol Biol Rep 36:1441-9. 2009..The phylogenetic relationships were reconstructed with the concatenated sequences of the 13 PCGs of the mitochondrial genome, which confirmed that P. atrilineata is most closely related to the superfamily Bombycoidea...
- A helitron-like transposon superfamily from lepidoptera disrupts (GAAA)(n) microsatellites and is responsible for flanking sequence similarity within a microsatellite familyBrad S Coates
USDA ARS, Iowa State University, Ames, 50011, USA
J Mol Evol 70:275-88. 2010..Transposition of MINE-1 members in Lepidoptera has resulted in the disruption of (GAAA)(n) microsatellite loci, has impacted the application of microsatellite-..
- Mapping the larval midgut lumen proteome of Helicoverpa armigera, a generalist herbivorous insectYannick Pauchet
Department of Entomology and Mass Spectrometry Research Group, Max Planck Institute for Chemical Ecology, Hans Knöll Str 8, D 07745 Jena, Germany
J Proteome Res 7:1629-39. 2008..Identification of the set of proteins that are secreted into the lumen will enable us to further characterize the nutritional and defensive functions of this important intraorganismal space...
- Silencing a cotton bollworm P450 monooxygenase gene by plant-mediated RNAi impairs larval tolerance of gossypolYing Bo Mao
National Key Laboratory of Plant Molecular Genetics, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, P R China
Nat Biotechnol 25:1307-13. 2007....
- Antennal SNMPs (sensory neuron membrane proteins) of Lepidoptera define a unique family of invertebrate CD36-like proteinsM E Rogers
Department of Biological Sciences, University of South Carolina, Columbia, South Carolina 29208, USA
J Neurobiol 49:47-61. 2001..The SNMPs are the only identified neuronal members of the CD36 family, and as such expand the activities of this gene family into roles influencing brain function and behavioral action...
- Ikappabeta-related vankyrin genes in the Campoletis sonorensis ichnovirus: temporal and tissue-specific patterns of expression in parasitized Heliothis virescens lepidopteran hostsJeremy A Kroemer
University of Kentucky, Department of Entomology, S 225 Agricultural Sciences Center North, Lexington, KY 40546, USA
J Virol 79:7617-28. 2005..We hypothesize that PDV vankyrin genes may suppress NF-kappabeta activity during immune responses and developmental cascades in parasitized lepidopteran hosts of C. sonorensis...
- Why are there so many species of herbivorous insects in tropical rainforests?Vojtech Novotny
Institute of Entomology, Czech Academy of Sciences and Department of Zoology, University of South Bohemia, Branisovska 31, 370 05 Ceske Budejovice, Czech Republic
Science 313:1115-8. 2006..These findings suggest that the latitudinal gradient in insect species richness could be a direct function of plant diversity, which increased sevenfold from our temperate to tropical study sites...
- Knockdown of aminopeptidase-N from Helicoverpa armigera larvae and in transfected Sf21 cells by RNA interference reveals its functional interaction with Bacillus thuringiensis insecticidal protein Cry1AcSwaminathan Sivakumar
International Centre for Genetic Engineering and Biotechnology, New Delhi 110 067, India
J Biol Chem 282:7312-9. 2007..BIAcore analysis of HaAPN1/Cry1Ac interaction further established HaAPN1 as a ligand for Cry1Ac. This is the first functional demonstration of insect aminopeptidase-N of H. armigera being a receptor of Cry1Ac protein of B. thuringiensis...
- Identification, cloning and expression of a Cry1Ab cadherin receptor from European corn borer, Ostrinia nubilalis (Hubner) (Lepidoptera: Crambidae)Ronald D Flannagan
Pioneer Hi Bred International Inc, 7301 NW 62nd Avenue, P O Box 85, Johnston, IA 50131 0085, USA
Insect Biochem Mol Biol 35:33-40. 2005..1 microg/ml. These results in combination suggest strongly that a cadherin-like protein acts as receptor and is involved with Cry1Ab toxicity in O. nubilalis...
- Cell wall composition as a maize defense mechanism against corn borersJaime Barros-Rios
Misión Biológica de Galicia CSIC, Apartado 28, E 36080 Pontevedra, Spain
Phytochemistry 72:365-71. 2011..Higher total cell wall, xylose, and 8-coupled diferulates concentrations appear to be possible mechanisms of corn borer resistance...
- Biological identifications through DNA barcodesPaul D N Hebert
Department of Zoology, University of Guelph, Guelph, Ontario N1G 2W1, Canada
Proc Biol Sci 270:313-21. 2003..Its assembly will also generate important new insights into the diversification of life and the rules of molecular evolution...
- Genetic structure of the polyphagous pest Helicoverpa armigera (Lepidoptera: Noctuidae) across the Sub-Saharan cotton beltJean Michel Vassal
CIRAD, FR 34398 Montpellier, France
Commun Agric Appl Biol Sci 73:433-7. 2008The cotton bollworm Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae) is a key pest of various cropping systems in West and Central Africa, and developed insecticide resistance recently...
- Cloning, expression and characterization of four serpin-1 cDNA variants from the spruce budworm, Choristoneura fumiferanaY P Zheng
Great Lakes Forestry Center, Canadian Forest Service, Sault Ste Marie, ON, Canada
Comp Biochem Physiol B Biochem Mol Biol 154:165-73. 2009..Cfserpin-1a could bind with the serine proteinase elastase and form a complex in vitro. We hypothesize that the cloned serpins could be involved in the regulation of cuticle degradation during the insect molting cycle...
- Molecular identification and characterization of two new Lepidoptera chemoreceptors belonging to the Drosophila melanogaster OR83b familyS Malpel
INRA UPMC AgroParisTech UMR 1272 PISC Physiologie de l Insecte Signalisation et Communication, Versailles, France
Insect Mol Biol 17:587-96. 2008..transmembrane domains and an unusual topology with intracellular N-termini and extracellular C-termini, extending to Lepidoptera the hypothesis of an inverted topology for DOR83b orthologues, demonstrated to date only in D. melanogaster.
- Phylogeny of the mega-diverse Gelechioidea (Lepidoptera): adaptations and determinants of successLauri Kaila
Finnish Museum of Natural History, University of Helsinki, PO Box 17, Helsinki 00014, Finland
Mol Phylogenet Evol 61:801-9. 2011....
- Molecular identification and phylogenetic analysis of baculoviruses from LepidopteraJohannes A Jehle
Laboratory for Biotechnological Crop Protection, Department of Phytopathology, Agricultural Service Center Palatinate DLR Rheinpfalz, Breitenweg 71, 67435 Neustadt an der Weinstrasse, Germany
Virology 346:180-93. 2006....
- Subcellular localization of the fatty acyl reductase involved in pheromone biosynthesis in the tobacco budworm, Heliothis virescens (Noctuidae: Lepidoptera)Asa K Hagström
Pheromone Group, Department of Biology, Lund University, Solvegatan 37, SE 223 62 Lund, Sweden
Insect Biochem Mol Biol 43:510-21. 2013..These results, together with previous data on the localization of desaturases, confirm the importance of the ER as a subcellular site of pheromone production...
- Evidence that the caterpillar salivary enzyme glucose oxidase provides herbivore offense in solanaceous plantsRichard O Musser
Department of Biological Sciences, Western Illinois University, Macomb, Illinois, USA
Arch Insect Biochem Physiol 58:128-37. 2005..Glucose oxidase is the first insect salivary enzyme shown to suppress wound-inducible herbivore defenses of plants...
- Plant allelochemicals differentially regulate Helicoverpa zea cytochrome P450 genesXianchun Li
Department of Plant Protection, Nanjing Agricultural University, Nanjing, China
Insect Mol Biol 11:343-51. 2002....
- Assessing the value of DNA barcodes for molecular phylogenetics: effect of increased taxon sampling in lepidopteraJohn James Wilson
Department of Integrative Biology, University of Guelph, Guelph, Ontario, Canada
PLoS ONE 6:e24769. 2011..Here I test this hypothesis using a large dataset of macrolepidopteran DNA barcodes...
- Coevolution between pathogen-derived proteinases and proteinase inhibitors of host insectsAndreas Vilcinskas
Justus Liebig University of Giessen, Institute of Phytopathology and Applied Zoology at the Interdisciplinary Research Center, Giessen, Germany
Virulence 1:206-14. 2010....
- Flavin-dependent monooxygenases as a detoxification mechanism in insects: new insights from the arctiids (lepidoptera)Sven Sehlmeyer
Institute for Pharmaceutical Biology, TU Braunschweig, Braunschweig, Germany
PLoS ONE 5:e10435. 2010..However, the previously identified senecionine N-oxygenase of the arctiid moth Tyria jacobaeae (Lepidoptera) indicates that FMOs have been recruited during the adaptation of this insect to plants that accumulate toxic ..
- Baculovirus per os infectivity factors form a complex on the surface of occlusion-derived virusKe Peng
Laboratory of Virology, Wageningen University, Droevendaalsesteeg 1, 6708 PB Wageningen, The Netherlands
J Virol 84:9497-504. 2010..We propose that PIF1, PIF2, PIF3, and P74 form an evolutionarily conserved complex on the ODV surface, which has an essential function in the initial stages of baculovirus oral infection...
- Reduced levels of membrane-bound alkaline phosphatase are common to lepidopteran strains resistant to Cry toxins from Bacillus thuringiensisJuan Luis Jurat-Fuentes
Department of Entomology and Plant Pathology, University of Tennessee, Knoxville, Tennessee, United States of America
PLoS ONE 6:e17606. 2011....
- Fusion proteins containing insect-specific toxins as pest control agents: snowdrop lectin delivers fused insecticidal spider venom toxin to insect haemolymph following oral ingestionElaine Fitches
Central Science Laboratory, Department for Environment, Food and Rural Affairs, Sand Hutton, York YO41 1LZ, UK
J Insect Physiol 50:61-71. 2004..SFI1/GNA and similar fusion proteins offer a novel and effective approach for delivering haemolymph active toxins by oral administration, which could be used in crop protection by expression in transgenic plants...
- Population genetics of ecological communities with DNA barcodes: an example from New Guinea LepidopteraKathleen J Craft
Department of Plant Biology, University of Minnesota, Saint Paul, MN 55108, USA
Proc Natl Acad Sci U S A 107:5041-6. 2010..Contradictory estimates of host specificity and beta diversity in tropical Lepidoptera (moths and butterflies) from New Guinea and the Americas have sparked debate on the role of host-associated ..
- Purification and characterization of an N-acetylglucosamine-binding lectin from Koelreuteria paniculata seeds and its effect on the larval development of Callosobruchus maculatus (Coleoptera: Bruchidae) and Anagasta kuehniella (Lepidoptera: Pyralidae)Maria Ligia Rodrigues Macedo
Laboratório de Purificação de Proteínas e suas Funções Biológicas, Departamento de Ciencias Naturais, Universidade Federal de Mato Grosso do Sul UFMS, Avenida Olinto Mancini 1662, Colinos, CP 210, CEP 79603 011 Três Lagoas, MS, Brazil
J Agric Food Chem 51:2980-6. 2003..65% KpLec produced an LD(50), whereas 0.2% KpLec produced an ED(50). The transformation of genes coding for this lectin could be useful in the development of insect resistance in important agricultural crops...
- Adenanthera pavonina trypsin inhibitor retard growth of Anagasta kuehniella (Lepidoptera: Pyralidae)Maria Ligia Rodrigues Macedo
Laboratório de Purificação de Proteínas e suas Funções Biológicas, Depto De Tecnologia de Alimentos e Saúde Pública, CCBS, Universidade Federal de Mato Grosso do Sul, CP 549, CEP 79070 900, Brazil
Arch Insect Biochem Physiol 73:213-31. 2010..In addition, the tryptic activity in ApTI -fed larvae was sensitive to ApTI. These results suggest that ApTI have a potential antimetabolic effect when ingested by A. kuehniella...
- Diverse genetic basis of field-evolved resistance to Bt cotton in cotton bollworm from ChinaHaonan Zhang
Key Laboratory of Integrated Management of Crop Diseases and Pests Ministry of Education, College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China
Proc Natl Acad Sci U S A 109:10275-80. 2012..The results suggest that resistance management strategies must account for diverse resistance alleles in field-selected populations, including nonrecessive alleles...
- Laboratory and field evaluations of transgenic soybean exhibiting high-dose expression of a synthetic Bacillus thuringiensis cry1A gene for control of LepidopteraTed C MacRae
Monsanto Company, 700 Chesterfield Parkway West, Chesterfield, MO 63017, USA
J Econ Entomol 98:577-87. 2005..These results demonstrate that expression of TIC107 in soybean can not only achieve highly efficacious control of several lepidopterans under field conditions but also provide a high dose for effective insect resistance management...
- Salivary glucose oxidase from caterpillars mediates the induction of rapid and delayed-induced defenses in the tomato plantDonglan Tian
Department of Entomology, Center for Chemical Ecology, Penn State University, University Park, Pennsylvania, USA
PLoS ONE 7:e36168. 2012..Examination of saliva from other caterpillar species indicates that saliva from the noctuids Spodoptera exigua and Heliothis virescens also induced Pin2 transcripts...
- Molecular phylogeny of the small ermine moth genus Yponomeuta (Lepidoptera, Yponomeutidae) in the palaearcticHubert Turner
Evolutionary Biology, Institute for Biodiversity and Ecosystem Dynamics, University of Amsterdam, Amsterdam, The Netherlands
PLoS ONE 5:e9933. 2010The small ermine moth genus Yponomeuta (Lepidoptera, Yponomeutidae) contains 76 species that are specialist feeders on hosts from Celastraceae, Rosaceae, Salicaceae, and several other plant families...
- Physiology and glomerular projections of olfactory receptor neurons on the antenna of female Heliothis virescens (Lepidoptera: Noctuidae) responsive to behaviorally relevant odorsN K Hillier
Department of Biology, University of Utah, Room 201 South Biology, Salt Lake City, UT 84112, USA
J Comp Physiol A Neuroethol Sens Neural Behav Physiol 192:199-219. 2006..Noctuidae: Lepidoptera) were investigated using a combination of cut-sensillum recording and cobalt-lysine staining techniques...
- Mutation in acetylcholinesterase1 associated with triazophos resistance in rice stem borer, Chilo suppressalis (Lepidoptera: Pyralidae)Xiaojing Jiang
Key Laboratory of Monitoring and Management of Plant Diseases and Insects, Ministry of Agriculture, Nanjing Agricultural University, Weigang No 1, Nanjing 210095, China
Biochem Biophys Res Commun 378:269-72. 2009..The assay offers a prospect for rapid monitoring of resistance and assisting with the appropriate choice of insecticide for combating damage caused by C. suppressalis...
- A comprehensive characterization of the caspase gene family in insects from the order LepidopteraJuliette Courtiade
Department of Entomology, Max Planck Institute for Chemical Ecology, Jena, Germany
BMC Genomics 12:357. 2011..In Lepidoptera, apoptosis is crucial in processes such as metamorphosis or defending against baculovirus infection...
- Functional Domains of Bacillus thuringiensis EndotoxinsDONALD DEAN; Fiscal Year: 2007..these toxins bind to specific receptors on the mosquito midgut as recognized in model insect-toxin studies (the Lepidoptera-toxin paradigm); i.e...
- INTERFERENCE WITH STEROID RESPONSE GENES IN LEPIDOPTERALynn Riddiford; Fiscal Year: 2002..this FIRCA proposal is to determine whether the new technique of double stranded RNA interference will work in Lepidoptera to provide us with a means of studying the effects of loss-of-function of these various factors to ascertain ..
- NEUROENDOCRINE REGULATION OF ENDOCRINE GLANDSNOELLE GRANGER; Fiscal Year: 1992..The CA of Lepidoptera such as the tobacco hornworm, Manduca sexta, are directly innervated by axons of cerebral neurosecretory and ..
- NATURAL GENETIC VARIATION IN VIVO METABOLIC IMPACTWARD WATT; Fiscal Year: 1991..An insect study system (genus Colias; Lepidoptera, Pieridae) will be used...
- EVOLUTION OF IMMUNE RECOGNITION AND EVASIONAustin L Hughes; Fiscal Year: 2010..In addition, by increasing our understanding of the population diversity and evolutionary history of human immune system genes, this research will enhance our knowledge of human immune function in health and disease. ..
- Gene Duplication and Genome EvolutionAustin Hughes; Fiscal Year: 2004..5) Examining the role of transposable elements in duplication of genomic segments by testing for nonrandom association between these elements and putatively duplicated blocks in the yeast genome. ..
- Genetics and evolution of gene copy number polymorphismErik Dopman; Fiscal Year: 2008..These long-term objectives have been formulated to test specific predictions for genes with variable copies. [unreadable] [unreadable] [unreadable]..
- Nutritional and endocrine control of mosquito egg development.Aparna Telang; Fiscal Year: 2008..Identification and characterization of these genes should expand our understanding of hematophagy and pathogen transmission in mosquito vectors. [unreadable] [unreadable] [unreadable] [unreadable]..
- Enhancement of the Baculovirus Expression Vector SystemBruce Webb; Fiscal Year: 2008..The enhanced BEVS technology to be developed with this award has potential to significantly improve efficacy of protein production in all such medical applications. [unreadable] [unreadable] [unreadable]..
- Baculovirus envelope proteins and insect cellsGARY BLISSARD; Fiscal Year: 2009..In addition, results of many of these studies will be directly applicable to new and exciting biotechnological applications of baculoviruses in mammalian cells. ..
- Replication and processing of baculovirus genomesGEORGE ROHRMANN; Fiscal Year: 2005..From these studies, major advances in the elucidation of this important and possibly novel replication system are expected. ..
- Function of Laccases in Anopheles gambiaeMichael R Kanost; Fiscal Year: 2010..Disrupting laccase function may provide a new mechanism for controlling mosquito populations. ..
- Eradication of a Primary Filariasis Vector Population at an Endemic Field SiteSTEPHEN LEONARD DOBSON; Fiscal Year: 2010..Integration of the vector eradication strategy and the MDA approach will facilitate filariasis elimination in areas where MDA alone has failed. ..
- Engineering transgenic silkworms to produce spider silk fibersDonald Jarvis; Fiscal Year: 2008..These projects will exploit current knowledge of specific peptide motifs contributing tensile strength or elasticity to spider silks. [unreadable] [unreadable] [unreadable]..
- Genetics of Wing and Cell-Size Evolution in NasoniaJohn Werren; Fiscal Year: 2008....
- PROTEINASE SYSTEMS IN INSECT HEMOLYMPHMichael R Kanost; Fiscal Year: 2010..sexta, to apply this knowledge to insect vectors of human diseases, and to apply advantages of the M. sexta system for fundamental studies on the regulation of serine protease activity. ..
- SECRETIONS OF ARTHROPODSThomas Eisner; Fiscal Year: 2008..Insects are major vectors of disease. An understanding of how insects depend on natural products for regulation of their biotic interactions is of broad applied significance to both medicine and agriculture. [unreadable] [unreadable]..
- A Viral Vector for Gene Expression in InsectsRanjit Dasgupta; Fiscal Year: 2007..We expect to establish FHV vectors as a powerful new system to study gene function in a wide variety of medically important arthropods. ..
- Physiological response of Escherichia coli to temperature and desiccation stressSUSAN BORNSTEINFORST; Fiscal Year: 2008..coli die-off will be important for interpreting monitoring results of beaches and discerning whether elevated E. coli levels reflect human health risk. [unreadable] [unreadable] [unreadable] [unreadable]..
- Pilot Studies in Biochemistry of Anopheles gambiaeMichael Kanost; Fiscal Year: 2005..gambiae serpins and laccases. This project will be a start toward development of a new research area for the PI (mosquito biochemistry) that will build from his experience in biochemistry of other groups of insects. ..
- Evolutionary genomics of new Drosophila genesDAVEN PRESGRAVES; Fiscal Year: 2004..The methods developed will be applicable in comparative analysis of other genomes, including those of humans and their primate relatives. ..
- Vector Population Modification Using Wolbachia SymbiontsStephen Dobson; Fiscal Year: 2006..g., maternal transmission rates and Wolbachia effects on host fitness), simplifying discrimination between Culex infection types, and improving methods for field cage evaluation of Wolbachia control strategies. ..
- RECEPTORS FROM MOSQUITO AEDES AEGYPTI EXCRETORY SYSTEMPATRICIA PIETRANTONIO; Fiscal Year: 2002..Aegypti. To test the hypothesis, the applicant proposes to clone the receptor gene, localize the tissue expression by in situ hybridization and immunohistochemistry and express the protein in transformed cells. ..
- Computations of Fold Changes in Evolution of ProteinsNick Grishin; Fiscal Year: 2006..Finally, we will perform in silico evolution of model proteins under functional constraints and compare the results to those deduced from the analysis of natural sequences and structures. ..
- A novel transgenic silkworm system for recombinant glycoprotein productionDonald L Jarvis; Fiscal Year: 2010..Finally, these results will be of great interest to bioengineers working to overcome the evolutionary limitations of lower eukaryotic systems for recombinant glycoprotein production. ..
- Structural and Functional Studies on ProteinsJon Clardy; Fiscal Year: 2007..This scan, if successful, would provide functional annotation for the endogenous function of previously characterized small molecules. Finally, some polypeptides with antibiotic activity will be investigated. ..
- Apoptosis as an anti-viral response in mosquito midgutROLLIE CLEM; Fiscal Year: 2007..unreadable] [unreadable]..
- High-throughput Screens for P. falciparum Malaria (RMI)Jon Clardy; Fiscal Year: 2004..Multi-component screens, based on the GFP-assay, will also be developed, identifying chemotypes that reverse drug resistance to previously effective agents. ..
- N-GLYCOSYLATION MECHANISM IN INSECT CELLSDonald L Jarvis; Fiscal Year: 2010....
- APPLICATIONS OF NATURAL PRODUCTS TO CHEMICAL BIOLOGYJon Clardy; Fiscal Year: 2009....
- Highly Improved Bacterial Larvicides for Vector ControlBrian Federici; Fiscal Year: 2007..This collaboration has the common goal of having new products based on these recombinant bacteria on the market within five years, sooner if possible. ..
- Molecular mechanisms of X. nematophila-nematode interactionHeidi Goodrich Blair; Fiscal Year: 2007..nematophila during colonization, further define a colonization-specific regulon, and expand our knowledge of the role of a ubiquitous transcription factor in the natural ecology of a bacterium. [unreadable] [unreadable]..
- FUNCTIONAL ANALYSIS OF ANTIAPOPTOTIC IAP PROTEINSROLLIE CLEM; Fiscal Year: 2002....
- Phenotypic-based high throughput screens-Plasmodium(RMI)Jon Clardy; Fiscal Year: 2005..Identification of cellular factors involved in parasitic invasion and transmission at the host cell erythrocyte is critical for understanding parasitic pathogenesis and should aid in the development of effective chemotherapeutics. ..