Genomes and Genes
Summary: A diverse genus of minute freshwater CRUSTACEA, of the suborder CLADOCERA. They are a major food source for both young and adult freshwater fish.
Publications308 found, 100 shown here
- The ecoresponsive genome of Daphnia pulexJohn K Colbourne
Center for Genomics and Bioinformatics, Indiana University, 915 East Third Street, Bloomington, IN 47405, USA
Science 331:555-61. 2011We describe the draft genome of the microcrustacean Daphnia pulex, which is only 200 megabases and contains at least 30,907 genes...
- Extensive, recent intron gains in Daphnia populationsWenli Li
Biology Department, Indiana University, Bloomington, IN 47405, USA
Science 326:1260-2. 2009..approach that detected 24 discordant intron/exon boundaries between the whole-genome sequences of two Daphnia pulex isolates. Sequencing of presence/absence loci across a collection of D...
- Resolving the infection process reveals striking differences in the contribution of environment, genetics and phylogeny to host-parasite interactionsDavid Duneau
University of Basel, Zoological Institute, Vesalgasse 1, Basel, Switzerland
BMC Biol 9:11. 2011..We designed a new method using the Daphnia magna - Pasteuria ramosa system, one of the rare examples where coevolution has been documented, in order to ..
- Cloning of the unculturable parasite Pasteuria ramosa and its Daphnia host reveals extreme genotype-genotype interactionsPepijn Luijckx
Institut of Zoology, Evolutionsbiologie, University of Basel, Basel, Switzerland
Ecol Lett 14:125-31. 2011..We obtained the first clones of the unculturable bacterium Pasteuria ramosa, a parasite of Daphnia magna...
- The effects of multiple infections on the expression and evolution of virulence in a Daphnia-endoparasite systemFrida Ben-Ami
Zoologisches Institut, Evolutionsbiologie, Universitat Basel, Vesalgasse 1, CH 4051 Basel, Switzerland
Evolution 62:1700-11. 2008..we examined the outcome of mixed-isolate infections in individual hosts, using a single clone of the waterflea Daphnia magna and three isolates of its semelparous endoparasite Pasteuria ramosa...
- Development of an RNA interference method in the cladoceran crustacean Daphnia magnaYasuhiko Kato
Okazaki Institute for Integrative Bioscience, Myodaiji, Aichi, Japan
Dev Genes Evol 220:337-45. 2011..a technique to inject exogenous materials into ovulated eggs and developed a dsRNA-based RNAi method for Daphnia magna...
- Biological surface coating and molting inhibition as mechanisms of TiO2 nanoparticle toxicity in Daphnia magnaAndré Dabrunz
Institute for Environmental Sciences, University of Koblenz Landau, Landau, Germany
PLoS ONE 6:e20112. 2011..that suspensions of nanosized (∼100 nm initial mean diameter) titanium dioxide (nTiO(2)) led to toxicity in Daphnia magna at nominal concentrations of 3.8 (72-h EC(50)) and 0.73 mg/L (96-h EC(50))...
- Genome-wide analysis of tandem repeats in Daphnia pulex--a comparative approachChristoph Mayer
Department of Animal Ecology, Evolution and Biodiversity, Ruhr University Bochum, Bochum, Germany
BMC Genomics 11:277. 2010..In this study we analysed the TR characteristics in the genomes of Daphnia pulex and 11 other eukaryotic species...
- Toxicity of nanosized and bulk ZnO, CuO and TiO2 to bacteria Vibrio fischeri and crustaceans Daphnia magna and Thamnocephalus platyurusMargit Heinlaan
National Institute of Chemical Physics and Biophysics, Akadeemia tee 23, Tallinn 12618, Estonia
Chemosphere 71:1308-16. 2008..nanoparticles of ZnO, TiO2 and CuO is increasing, their (eco)toxicity to bacteria Vibrio fischeri and crustaceans Daphnia magna and Thamnocephalus platyurus was studied with a special emphasis on product formulations (nano or bulk ..
- Stoichiometry in an ecological context: testing for links between Daphnia P-content, growth rate and habitat preferenceWilliam R DeMott
Department of Biology, Indiana Purdue University, Fort Wayne, IN 46805, USA
Oecologia 142:20-7. 2005We used laboratory experiments with ten Daphnia taxa to test for links between Daphnia P-content, growth rate and habitat preference...
- Abortive meiosis in the oogenesis of parthenogenetic Daphnia pulexChizue Hiruta
Department of Natural History Sciences, Graduate School of Science, Hokkaido University, Kita 10 Nishi 8, Kita ku, Sapporo, Hokkaido 060 0810, Japan
Chromosome Res 18:833-40. 2010..was to precisely reveal the process and mechanism of parthenogenetic oogenesis and maintenance of diploidy in Daphnia pulex through histology, karyology, and immunohistochemistry...
- Evolutionary factors affecting Lactate dehydrogenase A and B variation in the Daphnia pulex species complexTeresa J Crease
Department of Integrative Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada
BMC Evol Biol 11:212. 2011..Two closely related Daphnia species can be distinguished by their electrophoretic Ldh genotype and habitat...
- The Dscam homologue of the crustacean Daphnia is diversified by alternative splicing like in insectsDaniela Brites
Zoologisches Institut, Evolutionsbiologie, Universitat Basel, Vesalgasse 1, Switzerland
Mol Biol Evol 25:1429-39. 2008..We describe structural, expression, and evolutionary aspects of a Dscam homolog in 2 species of the crustacean Daphnia. The Dscam of Daphnia generates up to 13,000 different transcripts by the alternative splicing of variable exons...
- Role of microcystins in poisoning and food ingestion inhibition of Daphnia galeata caused by the cyanobacterium Microcystis aeruginosaT Rohrlack
Research Group Ecology, Department of Biology, Humboldt University, D 10099 Berlin, Germany
Appl Environ Microbiol 65:737-9. 1999The effects of microcystins on Daphnia galeata, a typical filter-feeding grazer in eutrophic lakes, were investigated...
- Acute and chronic effects of nano- and non-nano-scale TiO(2) and ZnO particles on mobility and reproduction of the freshwater invertebrate Daphnia magnaKarin Wiench
BASF, Product Safety Regulations, Toxicology and Ecology, GUP CB Z470, Ludwigshafen, Germany
Chemosphere 76:1356-65. 2009..Therefore, the potential effects of nano-scale and non-nano-scale TiO(2) and ZnO on the water flea, Daphnia magna, were examined in 48-h acute toxicity tests using three different test media, several pigment formulations--..
- Toxicity and bioaccumulation of TiO2 nanoparticle aggregates in Daphnia magnaXiaoshan Zhu
Department of Civil, Environmental, and Sustainable Engineering, Arizona State University, USA
Chemosphere 78:209-15. 2010..including modified acute (72h) and chronic (21d) toxicity tests as well as nTiO(2) accumulation analysis using Daphnia magna as a model organism...
- Effects of particle composition and species on toxicity of metallic nanomaterials in aquatic organismsRobert J Griffitt
Center for Environmental and Human Toxicology, University of Florida, Gainesville, Florida 32911, USA
Environ Toxicol Chem 27:1972-8. 2008..in all organisms tested, with 48-h median lethal concentrations as low as 40 and 60 microg/L, respectively, in Daphnia pulex adults, whereas titanium dioxide did not cause toxicity in any of the tests...
- Phototoxicity of CdSe/ZnSe quantum dots with surface coatings of 3-mercaptopropionic acid or tri-n-octylphosphine oxide/gum arabic in Daphnia magna under environmentally relevant UV-B lightJungkon Kim
Department of Environmental Health, School of Public Health, Seoul National University, 28 Yunkeon, Chongro, Seoul 110 799, Republic of Korea
Aquat Toxicol 97:116-24. 2010..We performed an in vivo study employing Daphnia magna to evaluate the mechanism involved in toxicity of cadmium selenide/zinc selenide quantum dots (QDs) with ..
- Toxicity identification evaluation of leachates from municipal solid waste landfills: a multispecies approachMarina Isidori
Dipartimento di Scienze della Vita, Seconda Universita di Napoli, Via A Vivaldi, 43 I 81100, Caserta, Italy
Chemosphere 52:85-94. 2003..the freshwater rotifer Brachionus calyciflorus and the freshwater crustaceans Thamnocephalus platyurus and Daphnia magna...
- Synergistic toxic effect of nano-TiO and As(V) on Ceriodaphnia dubiaDemin Wang
Department of Civil, Architectural and Environmental Engineering, Missouri University of Science and Technology, Rolla, MO 65409, USA
Sci Total Environ 409:1351-6. 2011..Hydrodynamic size and sorption capacity were most important parameters for toxicity...
- Biotransformation and bioconcentration of pyrene in Daphnia magnaJarkko Akkanen
Department of Biology, Laboratory of Aquatic Ecology and Ecotoxicology, University of Joensuu, P O Box 111, FIN 80101, Joensuu, Finland
Aquat Toxicol 64:53-61. 2003Water fleas (Daphnia magna) were exposed to [14C]pyrene in the presence and absence of piperonyl butoxide (PBO), a general cytochrome P450 (CYP) inhibitor, in organic carbon-free artificial freshwater (AFW, DOC<0...
- Host-parasite 'Red Queen' dynamics archived in pond sedimentEllen Decaestecker
Laboratory of Aquatic Ecology and Evolutionary Biology, Katholieke Universiteit Leuven, Charles De Beriotstraat 32, 3000 Leuven, Belgium
Nature 450:870-3. 2007..Dormant stages of both the water flea Daphnia and its microparasites are conserved in lake sediments, providing an archive of past gene pools...
- Single nucleotide polymorphism discovery from expressed sequence tags in the waterflea Daphnia magnaLuisa Orsini
Laboratory of Aquatic Ecology and Evolutionary Biology, K, U, Leuven, CH, Deberiotstraat 32, 3000 Leuven, Belgium
BMC Genomics 12:309. 2011b>Daphnia (Crustacea: Cladocera) plays a central role in standing aquatic ecosystems, has a well known ecology and is widely used in population studies and environmental risk assessments...
- Prior residency does not always pay off--co-infections in DaphniaJennifer N Lohr
Ludwig Maximilians Universitat Munchen, Department Biologie II, Evolutionsökologie, Grosshaderner Strasse 2, D 82152 Planegg Martinsried, Germany
Parasitology 137:1493-500. 2010..We infected a single genotype of the waterflea Daphnia galeata with both the intestinal protozoan Caullerya mesnili and the haemolymph fungus Metschnikowia sp...
- Environmental sex determination in the branchiopod crustacean Daphnia magna: deep conservation of a Doublesex gene in the sex-determining pathwayYasuhiko Kato
Department of Biotechnology, Graduate School of Engineering, Osaka University, Osaka, Japan
PLoS Genet 7:e1001345. 2011..Here we report the identification of two Dsx genes from Daphnia magna, a freshwater branchiopod crustacean that parthenogenetically produces males in response to environmental ..
- The chemoreceptor genes of the waterflea Daphnia pulex: many Grs but no OrsD Carolina Peñalva-Arana
Department of Biology, Indiana University, Bloomington, IN 47405, USA
BMC Evol Biol 9:79. 2009..The keystone species Daphnia pulex, a well known crustacean, is the first aquatic invertebrate to have its genome sequenced...
- Acute toxicity of two CdSe/ZnSe quantum dots with different surface coating in Daphnia magna under various light conditionsJiyoun Lee
School of Public Health, Seoul National University, Seoul, 110 799 Korea
Environ Toxicol 25:593-600. 2010..In the present study, we employed freshwater macroinvertebrate, Daphnia magna, to evaluate toxicity characteristics of cadmium selenide/zinc selenide (CdSe/ZnSe) in relation to surface ..
- Expression of Bacillus cereus hemolysin II in Bacillus subtilis renders the bacteria pathogenic for the crustacean Daphnia magnaElena V Sineva
Laboratory of Molecular Microbiology, Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, Moscow Region, Russia
FEMS Microbiol Lett 299:110-9. 2009..the expression of hlyII in Bacillus subtilis renders the bacteria hemolytic and is able to kill the crustacean Daphnia magna. The hemolytic activity of hlyII-encoded B...
- Introduction of foreign DNA into the water flea, Daphnia magna, by electroporationYasuhiko Kato
Okazaki Institute for Integrative Bioscience, Japan
Ecotoxicology 19:589-92. 2010..This is the first report of gene introduction to daphnids and, together with the emerging genome sequences, will be useful for the expanding our use of daphnid in ecotoxicology...
- Quantitative DNA-methylation in Daphnia magna and effects of multigeneration Zn exposureM B Vandegehuchte
Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Ghent, Belgium
Comp Biochem Physiol C Toxicol Pharmacol 150:343-8. 2009..The presence of DNA methylation in Daphnia magna has only very recently been demonstrated, although not quantified...
- Ecotoxicity of nanoparticles of CuO and ZnO in natural waterI Blinova
Laboratory of Molecular Genetics, National Institute of Chemical Physics and Biophysics, Akadeemia tee 23, Tallinn 12618, Estonia
Environ Pollut 158:41-7. 2010..The acute toxicity of CuO and ZnO nanoparticles in artificial freshwater (AFW) and in natural waters to crustaceans Daphnia magna and Thamnocephalus platyurus and protozoan Tetrahymena thermophila was compared...
- Clonal erosion and genetic drift in cyclical parthenogens--the interplay between neutral and selective processesJ Vanoverbeke
Laboratory of Aquatic Ecology and Evolutionary Biology, KU Leuven, Leuven, Belgium
J Evol Biol 23:997-1012. 2010..Using a physiologically structured model of the life history of Daphnia, we investigated to what extent clonal erosion associated with selection during the clonal phase affects the ..
- Toxicity and bioaccumulation of xenobiotic organic compounds in the presence of aqueous suspensions of aggregates of nano-C(60)A Baun
Department of Environmental Engineering, Technical University of Denmark, Building 113, DK 2800 Kgs Lyngby, Denmark
Aquat Toxicol 86:379-87. 2008..systems was studied in a series of toxicity tests with algae (Pseudokirchneriella subcapitata) and crustaceans (Daphnia magna)...
- Effects of pesticides on community structure and ecosystem functions in agricultural streams of three biogeographical regions in EuropeRalf Bernhard Schäfer
UFZ Helmholtz Centre for Environmental Research, Dept System Ecotoxicology, Permoser Strasse 15, 04318 Leipzig, Germany
Sci Total Environ 382:272-85. 2007..the community structure was detectable at a concentration range as low as 1/100 to 1/1000 the acute 48 h-LC50 of Daphnia magna...
- Fractionating nanosilver: importance for determining toxicity to aquatic test organismsAlan J Kennedy
US Army Engineer Research and Development Center, Vicksburg, Mississippi 39180, United States
Environ Sci Technol 44:9571-7. 2010..and coatings (citrate, polyvinylpyrrolidone, EDTA, proprietary) was assessed using three aquatic test organisms (Daphnia magna, Pimephales promelas, Pseudokirchneriella subcapitata)...
- Assays with Daphnia magna and Danio rerio as alert systems in aquatic toxicologyJ Martins
Departamento de Zoologia e Antropologia, Faculdade de Ciencias, Universidade do Porto, Praça Gomes Teixeira, 4099 002 Porto, Portugal
Environ Int 33:414-25. 2007..The aim of this research was to evaluate the use of ecotoxicity assays with Daphnia magna and Danio rerio as alert systems in water contaminated with toxic substances...
- Ecotoxicity of engineered nanoparticles to aquatic invertebrates: a brief review and recommendations for future toxicity testingA Baun
Department of Environmental Engineering, Technical University of Denmark, Miljoevej, Building 113, 2800 Kgs Lyngby, Denmark
Ecotoxicology 17:387-95. 2008..In addition, the majority of the studies have used Daphnia magna as the test organism...
- Postexposure feeding depression: a new toxicity endpoint for use in laboratory studies with Daphnia magnaRuth A McWilliam
Environment Group, Institute of Aquaculture, University of Stirling, Scotland, United Kingdom
Environ Toxicol Chem 21:1198-205. 2002..Previous studies have indicated that Daphnia magna exposed to toxic substances can exhibit delayed recovery in feeding behavior (postexposure feeding ..
- Cryptic intercontinental colonization in water fleas Daphnia pulicaria inferred from phylogenetic analysis of mitochondrial DNA variationSilvia Markova
Department of Ecology, Faculty of Science, Charles University, Prague 2, Czech Republic
Mol Phylogenet Evol 44:42-52. 2007The water fleas of the Daphnia pulex complex play a key role in freshwater ecosystems throughout the northern hemisphere...
- Natural selection for grazer resistance to toxic cyanobacteria: evolution of phenotypic plasticity?N G Hairston
Department of Ecology and Evolutionary Biology, Cornell University, Ithaca, New York 14853, USA
Evolution 55:2203-14. 2001We studied the selection response of the freshwater grazing zooplankter, Daphnia galeata, to increased abundance of cyanobacteria in its environment. Cyanobacteria are a poor-quality and often toxic food. Distinct genotypes of D...
- Analyzing effects of pesticides on invertebrate communities in streamsMatthias Liess
UFZ Centre for Environmental Research, Permoserstrasse 15, D 04318 Leipzig, Germany
Environ Toxicol Chem 24:954-65. 2005..showed that measured pesticide concentrations of 1:10 of the acute 48-h median lethal concentration (LC50) of Daphnia magna led to a short- and long-term reduction of abundance and number of SPEAR and a corresponding increase in ..
- Exploring embryonic germ line development in the water flea, Daphnia magna, by zinc-finger-containing VASA as a markerKazunori Sagawa
School of Life Science, Tokyo University of Pharmacy and Life Science, Hachioji, Japan
Gene Expr Patterns 5:669-78. 2005..on germ line development in crustaceans, we cloned VASA cDNAs from three branchiopod species: water fleas Daphnia magna and Moina macrocopa, and brine shrimp Artemia franciscana...
- Genetic diversity of Daphnia magna populations enhances resistance to parasitesFlorian Altermatt
Zoologisches Institut, Universitat Basel, Vesalgasse 1, CH 4051 Basel, Switzerland
Ecol Lett 11:918-28. 2008..We followed the spread of a microsporidian parasite in semi-natural outdoor Daphnia magna populations of low and high genetic diversity...
- Rapid evolution and ecological host-parasite dynamicsMeghan A Duffy
W K Kellogg Biological Station, Michigan State University, 3700 E Gull Lake Drive, Hickory Corners, MI 49060, USA
Ecol Lett 10:44-53. 2007..Focusing on a particular host-parasite system, Daphnia dentifera and its parasite Metschnikowia bicuspidata, we show that Daphnia from lakes with recent epidemics were ..
- The cost of being common: evidence from natural Daphnia populationsJustyna Wolinska
Indiana University, Department of Biology, Bloomington, Indiana 47405, USA
Evolution 63:1893-901. 2009..Queen theory operates in the wild, we studied the genetic structure of populations of the crustacean waterflea (Daphnia), in relation to their infection levels, for which we collected multiple samples from a variety of lakes...
- Profiling sex-biased gene expression during parthenogenetic reproduction in Daphnia pulexBrian D Eads
The Center for Genomics and Bioinformatics and Department of Biology, Indiana University Bloomington, Indiana 47405, USA
BMC Genomics 8:464. 2007..microarray to investigate gene expression in males and two reproductive stages of females in the crustacean Daphnia pulex...
- Embryological aspects of inducible morphological defenses in DaphniaChristian Laforsch
Section of Evolutionary Ecology and GeoBioCenter, Department of Biology II, Ludwig Maximilians Universitat Munchen, 82152 Planegg Martinsried, Germany
J Morphol 262:701-7. 2004..We compared for the first time in five different Daphnia species the embryonic development of predator-induced and noninduced animals using scanning electron microscopy (..
- Estimation of cumulative aquatic exposure and risk due to silver: contribution of nano-functionalized plastics and textilesSabine A Blaser
Institute for Chemical and Bioengineering, ETH Zurich, CH 8093 Zurich, Switzerland
Sci Total Environ 390:396-409. 2008..However, our study indicates that PEC/PNEC ratios greater than 1 cannot be ruled out for freshwater ecosystems, in particular sediments. No risk is predicted for microbial communities in sewage treatment plants...
- Development of a base set of toxicity tests using ultrafine TiO2 particles as a component of nanoparticle risk managementDavid B Warheit
DuPont Haskell Laboratory for Health and Environmental Sciences, Newark, DE 19714 0050, USA
Toxicol Lett 171:99-110. 2007..uf-TiO(2) exhibited low concern for aquatic hazard in unaerated, 48h, static acute tests using the water flea, Daphnia magna; exhibited low concern for aquatic hazard in unaerated, 96h, static acute tests using the rainbow trout, ..
- Protection against the toxicity of microcystin-LR and cylindrospermopsin in Artemia salina and Daphnia spp. by pre-treatment with cyanobacterial lipopolysaccharide (LPS)J Lindsay
Division of Environmental and Applied Biology, School of Life Sciences, University of Dundee, Dundee DD1 4HN, UK
Toxicon 48:995-1001. 2006..cyanobacterial lipopolysaccharide (LPS) was not acutely toxic to three aquatic invertebrates (Artemia salina, Daphnia magna and Daphnia galeata) in immersion trials...
- Genetic variation for maternal effects on parasite susceptibilityM Stjernman
Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Ashworth Laboratories, Edinburgh, UK
J Evol Biol 24:2357-63. 2011..studied how maternal effects (high or low food availability to mothers) mediated the resistance of the crustacean Daphnia magna to its bacterial parasite Pasteuria ramosa...
- Comparison of nanosilver and ionic silver toxicity in Daphnia magna and Pimephales promelasSarah M Hoheisel
U S Environmental Protection Agency, Mid Continent Ecology Division, Duluth, MN, USA
Environ Toxicol Chem 31:2557-63. 2012..the potency of nanosilver to ionic silver (Ag(+)) at acute and sublethal levels using two test organisms (Daphnia magna and Pimephales promelas). The 48-h D...
- The effect of fullerenes and functionalized fullerenes on Daphnia magna phototaxis and swimming behaviorKathryn A Brausch
The Institute of Environmental and Human Health, Texas Tech University, Lubbock, Texas, USA
Environ Toxicol Chem 30:878-84. 2011..Previous studies have reported alteration in Daphnia magna behavior, including increased hopping frequency, heart rate, and appendage movement in response to ..
- Acute toxicity of nanosized TiO(2) to Daphnia magna under UVA irradiationIrene Amiano
GLP Ecotoxicity Laboratory, Tecnalia, Azpeitia, Spain
Environ Toxicol Chem 31:2564-6. 2012..and the expected solar UVA contribution, will allow a more realistic understanding of the toxicity of TiO(2) to Daphnia magna. The results show that the contribution of UVA to TiO(2) toxicity cannot be ignored...
- Reticulate evolution of the Daphnia pulex complex as revealed by nuclear markersRoland Vergilino
Departement de Biologie, Centre d Etudes Nordiques, Universite du Quebec a Rimouski, Quebec, Canada
Mol Ecol 20:1191-207. 2011..The Daphnia pulex complex has been intensively studied as it includes species that dominate freshwater environments in the ..
- Metabolomics of microliter hemolymph samples enables an improved understanding of the combined metabolic and transcriptional responses of Daphnia magna to cadmiumHelen C Poynton
National Exposure Research Laboratory, U S Environmental Protection Agency, Cincinnati, Ohio, United States
Environ Sci Technol 45:3710-7. 2011..and whole-body transcriptome to reveal early processes leading to chronic toxicity in the indicator species, Daphnia magna, after 24-h sublethal cadmium exposure (18 μg/L, corresponding to 1/10 LC(50))...
- Predator-induced defense makes Daphnia more vulnerable to parasitesMingbo Yin
Ludwig Maximilians University Munich, Department Biology II, Grosshaderner Str 2, D 82152 Planegg Martinsried, Germany
Evolution 65:1482-8. 2011..Our current work reveals a significant cost to inducible defenses. Using the waterflea (Daphnia) model system, we show that induced defended morphs are significantly more vulnerable to infection by a virulent ..
- Life stage- dependent bioconcentration of a nonylphenol isomer in Daphnia magnaThomas G Preuss
Institute of Environmental Research Biology V, Aachen University, Worringerweg 1, D 52066 Aachen, Germany
Environ Pollut 156:1211-7. 2008..In this study we used a radiolabeled nonylphenol isomer to investigate the bioconcentration in Daphnia magna at different ages. Apart from the total radioactivity we measured the metabolism of p353-NP in D...
- High mutation rates in the mitochondrial genomes of Daphnia pulexSen Xu
Great Lakes Institute for Environmental Research, University of Windsor, Windsor, Ontario, Canada
Mol Biol Evol 29:763-9. 2012..In this study, we directly estimate the mtDNA mutation rate and spectrum using Daphnia pulex mutation-accumulation (MA) lines derived from sexual (cyclically parthenogenetic) and asexual (obligately ..
- Histaminergic signaling in the central nervous system of Daphnia and a role for it in the control of phototactic behaviorMatthew D McCoole
Department of Toxicology, College of Pharmacy, University of Louisiana at Monroe, 700 University Avenue, Monroe, LA 71209, USA
J Exp Biol 214:1773-82. 2011b>Daphnia magna and Daphnia pulex are well-established model organisms in the fields of ecotoxicology and toxicogenomics...
- Ecological context influences epidemic size and parasite-driven evolutionMeghan A Duffy
School of Biology, Georgia Institute of Technology, Atlanta, GA 30332 0230, USA
Science 335:1636-8. 2012..Consequently, anthropogenic alteration of productivity and predation might strongly influence both ecological and evolutionary outcomes of disease...
- Potential synergistic effects of microcystins and bacterial lipopolysaccharides on life history traits of Daphnia galeata raised on low and high food levelsL Miguel Dionisio Pires
Netherlands Institute of Ecology, Department of Aquatic Ecology, 6700 AB Wageningen, The Netherlands
Aquat Toxicol 104:230-42. 2011Metastudies have found no consistent effects of the cyanobacterial toxin microcystin on Daphnia, and there are discrepancies between field observations and experiments...
- Epidemiological, evolutionary, and coevolutionary implications of context-dependent parasitismPedro F Vale
Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Ashworth Labs, West Mains Road, Edinburgh, Scotland, United Kingdom
Am Nat 177:510-21. 2011..In experimental infections of the crustacean Daphnia magna and its bacterial parasite Pasteuria ramosa, we show how easily an interaction can shift from a severe ..
- Changes in the Daphnia magna midgut upon ingestion of copper oxide nanoparticles: a transmission electron microscopy studyMargit Heinlaan
Laboratory of Molecular Genetics, National Institute of Chemical Physics and Biophysics, Akadeemia tee 23, 12618 Tallinn, Estonia
Water Res 45:179-90. 2011..where we showed about 50-fold higher acute toxicity of CuO nanoparticles (NPs) compared to bulk CuO to water flea Daphnia magna...
- Morphological changes in Daphnia galeata induced by a crustacean terpenoid hormone and its analogShigeto Oda
National Institute for Environmental Studies, Tsukuba, Ibaraki, Japan
Environ Toxicol Chem 30:232-8. 2011..In the present study, morphological changes known as antipredatory responses in a cladoceran Daphnia galeata in response to exposure to MF and a juvenile hormone-mimicking pesticide, fenoxycarb, were investigated...
- Elaborate regulations of the predator-induced polyphenism in the water flea Daphnia pulex: kairomone-sensitive periods and life-history tradeoffsMaki Imai
Laboratory of Ecological Genetics, Graduate School of Environmental Science, Hokkaido University, Sapporo, Hokkaido, Japan
J Exp Zool A Ecol Genet Physiol 311:788-95. 2009Adaptive polyphenism produces alternative phenotypes depending on environmental stimuli. The water flea Daphnia pulex shows predator-induced polyphenism, facultatively forming neckteeth in response to kairomones released by Chaoborus ..
- Direct and transgenerational impact on Daphnia magna of chemicals with a known effect on DNA methylationMichiel B Vandegehuchte
Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, J Plateaustraat 22, B 9000 Ghent, Belgium
Comp Biochem Physiol C Toxicol Pharmacol 151:278-85. 2010The purpose of this study is to investigate (1) the induction of epigenetic effects in the crustacean Daphnia magna using DNA methylation as an epigenetic mark and (2) the potential stable transfer of such an epigenetic effect to non-..
- Rapid, local adaptation of zooplankton behavior to changes in predation pressure in the absence of neutral genetic changesC Cousyn
Laboratory of Aquatic Ecology, Katholieke Universiteit Leuven, Ch. De Beriotstraat 32, B-3000 Leuven, Belgium
Proc Natl Acad Sci U S A 98:6256-60. 2001..Starting from a natural resting egg bank of the waterflea Daphnia, we compare the evolutionary rates of change in an adaptive quantitative trait with those in selectively neutral ..
- A comparative study of rac- and S-metolachlor toxicity to Daphnia magnaHuijun Liu
Institute of Environmental Science, Department of Environmental Science, Zhejiang University, P O Box 3041, Hangzhou, Zhejiang Province 310029, China
Ecotoxicol Environ Saf 63:451-5. 2006..The acute and chronic toxicities of rac- and S-metolachlor to Daphnia magna were determined and compared in this study. The acute 24-h LC50s for rac- and S-metolachlor to D...
- Mixed inoculations of a microsporidian parasite with horizontal and vertical infectionsDita B Vizoso
Departement de Biologie, Unité d écologie and évolution, Universite de Fribourg, Chemin du Musee 10, 1700 Fribourg, Switzerland
Oecologia 143:157-66. 2005..isolates of Octosporea bayeri (Microsporidia) and their effect on the reproduction and longevity of its host Daphnia magna (Cladocera), after single- or double-isolate inoculations through vertical and horizontal transmission...
- Intraspecific competition delays recovery of population structureMatthias Liess
UFZ Helmholtz Centre for Environmental Research, Department of System Ecotoxicology, Permoserstrasse 15, D 04318 Leipzig, Germany
Aquat Toxicol 97:15-22. 2010..To test these hypotheses we exposed populations of Daphnia magna to a pulse of the pyrethroid Fenvalerate...
- LTR retroelements in the genome of Daphnia pulexMina Rho
School of Informatics and Computing, Indiana University, Bloomington, IN 47405, USA
BMC Genomics 11:425. 2010..Here, we present a genome-wide analysis of LTR retroelements in Daphnia pulex, a cyclical parthenogen and the first crustacean for which the whole genomic sequence is available...
- Inference of parasite local adaptation using two different fitness componentsD Refardt
Unité Ecologie et Evolution, Departement de Biologie, Chemin du Musee 10, Fribourg, Switzerland
J Evol Biol 20:921-9. 2007..We assessed local adaptation of the microsporidium Ordospora colligata to its host, the crustacean Daphnia magna using two different parasite fitness components: infection persistence over several host generations in ..
- Effects of silver and cerium dioxide micro- and nano-sized particles on Daphnia magnaBirgit K Gaiser
Edinburgh Napier University, School of Health, Life and Social Sciences, Sighthill Campus, Sighthill Court, Edinburgh EH11 4BN, UK
J Environ Monit 13:1227-35. 2011Acute (96 h) and chronic (21 d) exposures of Daphnia magna neonates were carried out with nano- and micro-sized Ag and CeO(2) particles to assess the influence of both material and size of particles on mortality and moulting...
- Oxidative stress responses of Daphnia magna exposed to TiO(2) nanoparticles according to size fractionKi Tae Kim
Department of Environmental Science and Engineering, Gwangju Institute of Science and Technology GIST, 261 Cheom dan Gwagi ro, Buk Gu, Gwangju 500 712, South Korea
Sci Total Environ 408:2268-72. 2010..The effect of particle size on oxidative stress against titanium dioxide nanoparticle (TiO(2) NP) exposure to Daphnia magna was investigated with both acute and chronic toxicity tests...
- Gene up-regulation in response to predator kairomones in the water flea, Daphnia pulexHitoshi Miyakawa
Graduate School of Environmental Science, Hokkaido University, Sapporo, Hokkaido 060 0810, Japan
BMC Dev Biol 10:45. 2010..The genus Daphnia (Branchiopoda, Cladocera) provides a model experimental system for the study of the developmental mechanisms and ..
- Multi-metal interactions between Cd, Cu, Ni, Pb and Zn in water flea Daphnia magna, a stable isotope experimentI Komjarova
Department of Biology, University of Antwerp, Groenenborgerlaan 171, B 2020 Antwerp, Belgium
Aquat Toxicol 90:138-44. 2008Metal interaction effects were investigated in Daphnia magna during a simultaneous exposure to essential (Cu, Ni and Zn) and non-essential (Cd and Pb) metals at environmentally relevant concentrations using a stable isotope technique...
- Ribosomal DNA evolution at the population level: nucleotide variation in intergenic spacer arrays of Daphnia pulexT J Crease
Department of Zoology, University of Guelph, Ontario, Canada
Genetics 141:1327-37. 1995Nucleotide variation was surveyed in 21 subrepeat arrays from the ribosomal DNA intergenic spacer of three Daphnia pulex populations. Eighteen of these arrays contained four subrepeats...
- A comparison of nanoparticle and fine particle uptake by Daphnia magnaPhilipp Rosenkranz
School of Life Sciences, Edinburgh Napier University, 10 Colinton Road, Edinburgh, EHIO 5DT Scotland, United Kingdom
Environ Toxicol Chem 28:2142-9. 2009..of a model nanoparticle, a 20-nm fluorescent carboxylated polystyrene bead, in the aquatic invertebrate Daphnia magna and compared it to a larger, 1,000-nm particle...
- Mixtures of similarly acting compounds in Daphnia magna: from gene to metabolite and beyondTine Vandenbrouck
Department of Biology, Laboratory for Ecophysiology, Biochemistry and Toxicology, University of Antwerp, Groenenborgerlaan 171, Antwerp, Belgium
Environ Int 36:254-68. 2010b>Daphnia are an important and widely studied model species in ecological and toxicological studies throughout the world and an official (OECD) recommended test organism...
- Transgenerational effects of poor elemental food quality on Daphnia magnaPaul C Frost
Department of Biology, Trent University, Peterborough, ON K9J 7B8, Canada
Oecologia 162:865-72. 2010..We examined whether P limitation of the aquatic invertebrate, Daphnia magna, alters the responses of its offspring to inadequate P nutrition...
- Contribution of cyclic parthenogenesis and colonization history to population structure in DaphniaAnne Thielsch
Department of Ecology and Evolution, Goethe University Frankfurt am Main, Siesmayerstrasse 70, Frankfurt am Main, Germany
Mol Ecol 18:1616-28. 2009..Members of the cladoceran genus Daphnia are widely distributed key organisms in freshwater habitats, which mostly exhibit this reproduction mode...
- Influence of stability on the acute toxicity of CdSe/ZnS nanocrystals to Daphnia magnaHeather E Pace
Department of Environmental Science and Engineering, Colorado School of Mines, 1500 Illinois Street, Golden, Colorado 80401, USA
Environ Toxicol Chem 29:1338-44. 2010The acute toxicity of polymer-coated CdSe/ZnS quantum dots (QDs) to Daphnia magna was investigated using 48-h exposure studies. The principal objective was to relate the toxicity of QDs to specific physical and chemical aspects of the QD...
- Intracellular conversion of environmental nitrate and nitrite to nitric oxide with resulting developmental toxicity to the crustacean Daphnia magnaBethany R Hannas
Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, North Carolina, United States of America
PLoS ONE 5:e12453. 2010..We tested the hypothesis that NO(x) undergo intracellular conversion to the potent signaling molecule nitric oxide resulting in the disruption of endocrine-regulated processes...
- Genetic variation in a host-parasite association: potential for coevolution and frequency-dependent selectionH J Carius
Zoologisches Institut, Universitat Basel, Switzerland
Evolution 55:1136-45. 2001..We used the freshwater crustacean Daphnia magna and its bacterial microparasite Pasteuria ramosa to study genetic variation for host susceptibility and ..
- The impact of human-made ecological changes on the genetic architecture of Daphnia speciesNora Brede
Department of Ecology and Evolution, Goethe University Frankfurt am Main, Siesmayerstrasse 70, D 60054 Frankfurt am Main, Germany
Proc Natl Acad Sci U S A 106:4758-63. 2009..We reconstructed the genetic architecture of a Daphnia species complex in 2 European lakes using diapausing eggs that were isolated from sediment layers covering the ..
- Trophic transfer of TiO(2) nanoparticles from Daphnia to zebrafish in a simplified freshwater food chainXiaoshan Zhu
Department of Civil, Environmental, and Sustainable Engineering, Arizona State University, Tempe, AZ 85287, USA
Chemosphere 79:928-33. 2010..To address this concern, a simplified model of a freshwater food chain including a low trophic level organism (daphnia, Daphnia magna) and a high trophic level organism (zebrafish, Danio rerio) was established...
- Predator-induced defences in Daphnia pulex: selection and evaluation of internal reference genes for gene expression studies with real-time PCRKatina I Spanier
Department of Animal Ecology, Ruhr University Bochum, D 44780 Bochum, Germany
BMC Mol Biol 11:50. 2010The planktonic microcrustacean Daphnia pulex is among the best-studied animals in ecological, toxicological and evolutionary research. One aspect that has sustained interest in the study system is the ability of D...
- Ecological genomics: steps towards unraveling the genetic basis of inducible defenses in DaphniaRalph Tollrian
Department of Animal Ecology, Evolution and Biodiversity, Ruhr University Bochum, Universitaetsstrasse 150, D 44801 Bochum, Germany
BMC Biol 8:51. 2010Little is known about the genetic mechanisms underlying inducible defenses. Recently, the genome of Daphnia pulex, a model organism for defense studies, has been sequenced...
- The genetic legacy of polyploid Bolivian Daphnia: the tropical Andes as a source for the North and South American D. pulicaria complexJoachim Mergeay
Laboratory of Aquatic Ecology and Evolutionary Biology, Katholieke Universiteit Leuven, Charles Deberiotstraat 32, B 3000 Leuven, Belgium
Mol Ecol 17:1789-800. 2008We investigated genetic variation in asexual polyploid members of the water flea Daphnia pulex complex from a set of 12 Bolivian high-altitude lakes...
- Long-term disease dynamics in lakes: causes and consequences of chytrid infections in Daphnia populationsPieter T J Johnson
Ecology and Evolutionary Biology, Ramaley N122, Campus Box 334, University of Colorado, Boulder, Colorado 80309 0334, USA
Ecology 90:132-44. 2009..We examined the dynamics of Daphnia pulicaria, a keystone zooplankter in lake ecosystems, to explore the long-term causes and consequences of ..
- Meiosis genes in Daphnia pulex and the role of parthenogenesis in genome evolutionAndrew M Schurko
Roy J Carver Center for Comparative Genomics and Department of Biology, The University of Iowa, Iowa City, IA 52242, USA
BMC Evol Biol 9:78. 2009..However, little is understood about the molecular determinants of parthenogenesis. The Daphnia pulex genome must contain the molecular machinery for different reproductive modes: sexual (both male and female ..
- The first-generation Daphnia magna linkage mapJarkko Routtu
Zoologisches Institut, Evolutionsbiologie, Universitat Basel, Vesalgasse 1, 4051 Basel, Switzerland
BMC Genomics 11:508. 2010b>Daphnia magna is a well-established model species in ecotoxicology, ecology and evolution...
- The infection rate of Daphnia magna by Pasteuria ramosa conforms with the mass-action principleR R Regoes
Department of Biology, Emory University, 1510 Clifton Rd NE, Atlanta, GA 30322, USA
Epidemiol Infect 131:957-66. 2003..this paper, we examine the relationship between the infection rate and the parasite inoculum for the water flee Daphnia magna and its bacterial parasite Pasteuria ramosa...
- Maternal control of resting-egg production in DaphniaV Alekseev
Present address Zoological Institute of the Russian Academy of Sciences, St Petersburg, 199034
Nature 414:899-901. 2001..Like seeds, resting stages can survive unfavourable conditions. The crustacean Daphnia normally reproduces by means of parthenogenetically produced normal, not resting, eggs-but occasionally switches ..
- Sequence divergence and expression of a transformer gene in the branchiopod crustacean, Daphnia magnaYasuhiko Kato
Okazaki Institute for Integrative Bioscience, National Institute for Basic Biology, National Institutes of Natural Sciences, and Department of Basic Biology, Faculty of Life Science, Graduate University for Advanced Studies, 5 1 Higashiyama, Myodaiji, Okazaki, Aichi 444 8787, Japan
Genomics 95:160-5. 2010Environmental decline triggers a switch in reproductive strategy of Daphnia magna from asexual to sexual reproduction; however, the molecular basis of such environmental sex determination remains largely unknown...
- In vivo biomodification of lipid-coated carbon nanotubes by Daphnia magnaAaron P Roberts
Department of Biological Sciences, University of North Texas, Denton, Texas 76203, USA
Environ Sci Technol 41:3025-9. 2007This study examined the interactions between Daphnia magna and a water-soluble, lysophophatidylcholine coated single-walled carbon nanotube. D...
- Chronic toxicity and responses of several important enzymes in Daphnia magna on exposure to sublethal microcystin-LRWei Chen
State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, Hubei 430072, People s Republic of China
Environ Toxicol 20:323-30. 2005In the current study, the toxicological mechanisms of microcystin-LR and its disadvantageous effects on Daphnia magna were examined...
- Effects of cell-bound microcystins on survival and feeding of Daphnia sppT Rohrlack
Freshwater Biological Laboratory, University of Copenhagen, DK 3400 Hillerød, Denmark
Appl Environ Microbiol 67:3523-9. 2001The influence of cell-bound microcystins on the survival time and feeding rates of six Daphnia clones belonging to five common species was studied...
- Allochronic differentiation among Daphnia species, hybrids and backcrosses: the importance of sexual reproduction for population dynamics and genetic architectureT Jankowski
Limnological Institute, University of Konstanz, Konstanz, Germany
J Evol Biol 17:312-21. 2004Seasonal dynamics of the abundance, sexual reproduction and genetic architecture in a Daphnia hyalina-galeata hybrid complex were studied in the large and deep Lake Constance...
- Gene response profiles for Daphnia pulex exposed to the environmental stressor cadmium reveals novel crustacean metallothioneinsJoseph R Shaw
Department of Biology, Dartmouth College, Hanover, New Hampshire 03755, USA
BMC Genomics 8:477. 2007..A first generation cDNA microarray was developed for the environmental indicator species Daphnia pulex, to identify genes whose regulation is modulated following exposure to the metal stressor cadmium...
- Effects of environmental contamination on gene copy number variation: Molecular bJoseph Shaw; Fiscal Year: 2010..Accordingly, our proposal employs studies using the recently added and ideal NIH model organism, Daphnia, to test the central hypothesis that exposure to environmental contaminants increase the rate of mutations giving ..
- MUTATION, DRIFT, & THE RATE OF PHENOTYPIC EVOLUTIONMichael Lynch; Fiscal Year: 1992..information on the properties of polygenic mutation. Using three model systems (the microcrustacean Daphnia, the snail Lymnaea, and corn), we plan to initiate long-term mutation-accumulation experiments in order to: 1) ..
- MUTATION, DRIFT, & THE RATE OF PHENOTYPIC EVOLUTIONMichael Lynch; Fiscal Year: 1990..information on the properties of polygenic mutation. Using three model systems (the microcrustacean Daphnia, the snail Lymnaea, and corn), we plan to initiate long-term mutation-accumulation experiments in order to: 1) ..
- Expression and evolution of chemoreceptor genes in the model organism DaphniaDINORA PENALVA ARANA; Fiscal Year: 2009..The Daphnia genome has recently been sequenced and a set of 58 gustatory receptor genes (Grs) has been identified...
- Daphnia DNA MicroarraysOwen Hughes; Fiscal Year: 2002..Specifically, in this Phase I work we will construct a pilot array for Daphnia pulex...
- Expression and evolution of chemoreceptor genes in the model organism DaphniaDINORA CAROLINA PENALVA ARANA; Fiscal Year: 2010..The Daphnia genome has recently been sequenced and a set of 58 gustatory receptor genes (Grs) has been identified...
- CONSEQUENCES OF DELETERIOUS MUTATIONMichael Lynch; Fiscal Year: 1999..Empirical studies are proposed to determine the nature and rate of accumulation of mutations in Daphnia and Escherichia coli...
- CONSEQUENCES OF DELETERIOUS MUTATIONMichael Lynch; Fiscal Year: 1999..Empirical studies are proposed to determine the nature and rate of accumulation of mutations in Daphnia and Escherichia coli...
- Daphnia Functional Genomics ResourceMICHAEL PFRENDER; Fiscal Year: 2007..b>Daphnia is a logical candidate study system for further development to fill this gap...
- Daphnia Functional Genomics ResourceMICHAEL PFRENDER; Fiscal Year: 2009..b>Daphnia is a logical candidate study system for further development to fill this gap...
- Daphnia Functional Genomics ResourceMICHAEL EUGENE PFRENDER; Fiscal Year: 2010..b>Daphnia is a logical candidate study system for further development to fill this gap...
- MASS SPECTRAL SEQUENCING OF CARBOHYDRATESVernon Reinhold; Fiscal Year: 2007..To tackle this research area we introduce a new and more appropriate animal model Daphnia. We discuss the many reasons this simple microcrustacean is appropriate for the tasks ahead and supply ..
- MASS SPECTRAL SEQUENCING OF CARBOHYDRATESVernon Reinhold; Fiscal Year: 2006..To tackle this research area we introduce a new and more appropriate animal model Daphnia. We discuss the many reasons this simple microcrustacean is appropriate for the tasks ahead and supply ..
- MASS SPECTRAL SEQUENCING OF CARBOHYDRATESVernon Reinhold; Fiscal Year: 2009..To tackle this research area we introduce a new and more appropriate animal model Daphnia. We discuss the many reasons this simple microcrustacean is appropriate for the tasks ahead and supply ..
- CORE--Hazard IdentificationA Gandolfi; Fiscal Year: 2005..The Biological Response section will include ecotoxicity (bacterial and daphnia), mammalian cytotoxicity (HepG2 cells), and genotoxicity (Ames) assays...
- Fathead minnow DNA microarraysOwen Hughes; Fiscal Year: 2002..If this work proves feasibility, Phase II will involve developing a reasonably comprehensive Pimephales array as well as beginning arrays for Daphnia, duckweed, and green algae.
- CELLULAR INTERACTIONS IN SYNAPTOGENESISEduardo Macagno; Fiscal Year: 1980..On the basis of our observations on the visual system of Daphnia, we have proposed a spatio-temporal model in which particular cellular interactions underlie the formation of the ..
- Daphnia Functional Genomics ResourceMICHAEL PFRENDER; Fiscal Year: 2008..b>Daphnia is a logical candidate study system for further development to fill this gap...
- Induction of breast cancer in MMTVneu miceWilliam Baldwin; Fiscal Year: 2002..Overall, the purpose of this study is to examine 4-nonylphenol's effects on breast cancer growth and its mechanism of action on the mammary tumor. ..
- Genomic search for bone mass QTLsHong Wen Deng; Fiscal Year: 2010..This knowledge is essential for the development of preventive interventions and/or cures for osteoporosis that may be based on individuals'specific genotypes. ..
- The Rate and Molecular Spectrum of Spontaneous MutationsMichael Lynch; Fiscal Year: 2009..four model systems: the yeast Saccharomyces cerevisiae, the nematode Caenorhabditis elegans, the microcrustacean Daphnia pulex, and the ciliate Paramecium tetraurelia...
- NEURAL CONTROL OF SENSORY ACQUISITIONMark Nelson; Fiscal Year: 2000..This research is intended to lead to a better understanding of general principles of sensory acquisition that enable animals, including humans, to efficiently obtain and process information about their environment. ..
- CHARACTERIZATION OF DELETERIOUS GENOMIC MUTATIONSHong Wen Deng; Fiscal Year: 2000..abstract_text> ..
- Genomic search for bone mass QTLsHong Wen Deng; Fiscal Year: 2009..This knowledge is essential for the development of preventive interventions and/or cures for osteoporosis that may be based on individuals'specific genotypes. ..
- The Rate and Molecular Spectrum of Spontaneous MutationsMichael Lynch; Fiscal Year: 2007..four model systems: the yeast Saccharomyces cerevisiae, the nematode Caenorhabditis elegans, the microcrustacean Daphnia pulex, and the ciliate Paramecium tetraurelia...
- The Rate and Molecular Spectrum of Spontaneous MutationsMichael Lynch; Fiscal Year: 2008..four model systems: the yeast Saccharomyces cerevisiae, the nematode Caenorhabditis elegans, the microcrustacean Daphnia pulex, and the ciliate Paramecium tetraurelia...
- Characterization and genetic analysis of aging in DaphniaJeffry L Dudycha; Fiscal Year: 2010DESCRIPTION (provided by applicant): This project will develop the microcrustacean Daphnia as a model system for the biology of aging...
- ROBUST AND POWERFUL TEST OF CANDIDATE GENES TO BONE MASSHong Wen Deng; Fiscal Year: 2010....
- Identification of Proteins Important for Male OsteoporosisHong Wen Deng; Fiscal Year: 2010..This project aims to identify proteins that are important to male osteoporosis. The findings will provide essential scientific basis for effective prevention, diagnosis and treatment of the disease. ..
- The Rate and Molecular Spectrum of Spontaneous MutationsMichael Lynch; Fiscal Year: 2009
- NEURAL CONTROL OF SENSORY ACQUISITIONMark Nelson; Fiscal Year: 1999..This research is intended to lead to a better understanding of general principles of sensory acquisition that enable animals, including humans, to efficiently obtain and process information about their environment. ..
- The Rate and Molecular Spectrum of Spontaneous MutationsMichael Lynch; Fiscal Year: 2007
- Identification of Proteins Important for Male OsteoporosisHong Wen Deng; Fiscal Year: 2009..This project aims to identify proteins that are important to male osteoporosis. The findings will provide essential scientific basis for effective prevention, diagnosis and treatment of the disease. ..
- Genomic search for bone mass QTLsHong Wen Deng; Fiscal Year: 2008..This knowledge is essential for the development of preventive interventions and/or cures for osteoporosis that may be based on individuals' specific genotypes. ..
- ROBUST AND POWERFUL TEST OF CANDIDATE GENES TO BONE MASSHong Wen Deng; Fiscal Year: 2004..Our proposed study is comprehensive and our statistical genetic analyses show that our study is of very high power and may identify a quantitative trait locus (QTL) with a heritability (h2) as low as 0.05 with a power of > 90%. ..
- NEURAL CONTROL OF SENSORY ACQUISITIONMark Nelson; Fiscal Year: 2004..The modeling framework is used to quantitatively evaluate the contributions of afferent convergence and spatiotemporal filtering in the ELL maps to the enhancement of the signal and the suppression of the background. ..
- Directory and Information System components for genomesDonald Gilbert; Fiscal Year: 2003..Such a module for automated, common-standard use of organism genome data is an important step toward a grid of data useable for the large-scale analyses desired bioscientists. ..
- NEURAL CONTROL OF SENSORY ACQUISITIONMark Nelson; Fiscal Year: 2003..The modeling framework is used to quantitatively evaluate the contributions of afferent convergence and spatiotemporal filtering in the ELL maps to the enhancement of the signal and the suppression of the background. ..
- CHARACTERIZATION OF DELETERIOUS GENOMIC MUTATIONSHong Wen Deng; Fiscal Year: 2004..abstract_text> ..
- Genetic Basis of Osteoporotic Fractures and Bone MassHong Wen Deng; Fiscal Year: 2005..There are only a few remaining minor concerns. Five years of support are recommended with an outstanding level of enthusiasm. ..
- ROBUST AND POWERFUL TEST OF CANDIDATE GENES TO BONE MASSHong Wen Deng; Fiscal Year: 2005..Our proposed study is comprehensive and our statistical genetic analyses show that our study is of very high power and may identify a quantitative trait locus (QTL) with a heritability (h2) as low as 0.05 with a power of > 90%. ..
- CHARACTERIZATION OF DELETERIOUS GENOMIC MUTATIONSHong Wen Deng; Fiscal Year: 2005..abstract_text> ..
- Proteomics Study of Peripheral Blood Monocytes on OsteoporosisHong Wen Deng; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- CHARACTERIZATION OF DELETERIOUS GENOMIC MUTATIONSHong Wen Deng; Fiscal Year: 2001..abstract_text> ..
- ROBUST AND POWERFUL TEST OF CANDIDATE GENES TO BONE MASSHong Wen Deng; Fiscal Year: 2007..Our proposed study is comprehensive and our statistical genetic analyses show that our study is of very high power and may identify a quantitative trait locus (QTL) with a heritability (h2) as low as 0.05 with a power of > 90%. ..
- Genomic search for bone mass QTLsHong Wen Deng; Fiscal Year: 2007..This knowledge is essential for the development of preventive interventions and/or cures for osteoporosis that may be based on individuals' specific genotypes. ..
- The Rate and Molecular Spectrum of Spontaneous MutationsMichael Lynch; Fiscal Year: 2006
- NEURAL CONTROL OF SENSORY ACQUISITIONMark Nelson; Fiscal Year: 2002..The modeling framework is used to quantitatively evaluate the contributions of afferent convergence and spatiotemporal filtering in the ELL maps to the enhancement of the signal and the suppression of the background. ..
- ROBUST AND POWERFUL TEST OF CANDIDATE GENES TO BONE MASSHong Wen Deng; Fiscal Year: 2005
- CHARACTERIZATION OF DELETERIOUS GENOMIC MUTATIONSHong Wen Deng; Fiscal Year: 2002..abstract_text> ..
- ROBUST AND POWERFUL TEST OF CANDIDATE GENES TO BONE MASSHong Wen Deng; Fiscal Year: 2006
- Directory and Information System components for genomesDonald Gilbert; Fiscal Year: 2002..Such a module for automated, common-standard use of organism genome data is an important step toward a grid of data useable for the large-scale analyses desired bioscientists. ..