muridae

Summary

Summary: A family of the order Rodentia containing 250 genera including the two genera Mus (MICE) and Rattus (RATS), from which the laboratory inbred strains are developed. The fifteen subfamilies are SIGMODONTINAE (New World mice and rats), CRICETINAE, Spalacinae, Myospalacinae, Lophiomyinae, ARVICOLINAE, Platacanthomyinae, Nesomyinae, Otomyinae, Rhizomyinae, GERBILLINAE, Dendromurinae, Cricetomyinae, MURINAE (Old World mice and rats), and Hydromyinae.

Top Publications

  1. pmc Phylogeographic study of Apodemus ilex (Rodentia: Muridae) in Southwest China
    Qi Liu
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China
    PLoS ONE 7:e31453. 2012
  2. ncbi Allelic diversity at the Mhc-DQA locus in cotton rats (Sigmodon hispidus) and a comparison of DQA sequences within the family muridae (Mammalia: Rodentia)
    R S Pfau
    Department of Zoology 430 LSW, Oklahoma State University, Stillwater, OK 74078, USA
    Immunogenetics 49:886-93. 1999
  3. pmc Assessment of three mitochondrial genes (16S, Cytb, CO1) for identifying species in the Praomyini tribe (Rodentia: Muridae)
    Violaine Nicolas
    Museum national d histoire naturelle, Département de Systématique et Evolution UMR CNRS 7205, Paris, France
    PLoS ONE 7:e36586. 2012
  4. doi Dental microwear patterns of extant and extinct Muridae (Rodentia, Mammalia): ecological implications
    Helder Gomes Rodrigues
    Laboratoire de Paléontologie Paléobiologie Phylogénie, Institut des Sciences de l Evolution de l Université Montpellier II, UMR CNRS 5554 Case courrier 064, Place Eugene Bataillon, 34 095, Montpellier Cedex 5, France
    Naturwissenschaften 96:537-42. 2009
  5. ncbi Molecular phylogeny and taxonomy of wood mice (genus Apodemus Kaup, 1829) based on complete mtDNA cytochrome b sequences, with emphasis on Chinese species
    Xiaoming Liu
    Institute of Zoology, Chinese Academy of Sciences, Beijing 100080, China
    Mol Phylogenet Evol 33:1-15. 2004
  6. ncbi Testosterone depresses innate and acquired resistance to ticks in natural rodent hosts: a force for aggregated distributions of parasites
    V L Hughes
    Department of Zoology, University of Oxford, UK
    J Parasitol 87:49-54. 2001
  7. ncbi Restricted gene flow in Calomys musculinus (Rodentia, Muridae), the natural reservoir of Junin virus
    M B Chiappero
    Catedra de Bioquimica y Biologia Molecular, Facultad de Ciencias Medicas, Universidad Nacional de Cordoba, Casilla de Correo 35, Sucursal 16, 5016 Cordoba, Argentina
    J Hered 94:490-5. 2003
  8. ncbi Evolutionary conservation of whole homeologous chromosome arms in the Akodont rodents Bolomys and Akodon (Muridae, Sigmodontinae): maintenance of interstitial telomeric segments (ITBs) in recent event of centric fusion
    V Fagundes
    Departamento de Biologia, Universidade de Sao Paulo, Brazil
    Chromosome Res 6:643-8. 1998
  9. ncbi A spatial aspect on mitochondrial DNA genealogy in Apodemus peninsulae from East Asia
    Keiko Serizawa
    Laboratory of Ecology and Genetics, Graduate School of Environmental Earth Science, Hokkaido University, Sapporo, Japan
    Biochem Genet 40:149-61. 2002
  10. ncbi Syphacia longaecauda n. sp. (Nematoda: Oxyuridae) syphacinea from Melomys spp. (Muridae: Hydromyinae) from Papua New Guinea and Irian Jaya, Indonesia
    L R Smales
    School of Biological and Environmental Sciences, Central Queensland University, Rockhampton, Queensland 4700, Australia
    Parasite 8:39-43. 2001

Research Grants

Detail Information

Publications211 found, 100 shown here

  1. pmc Phylogeographic study of Apodemus ilex (Rodentia: Muridae) in Southwest China
    Qi Liu
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China
    PLoS ONE 7:e31453. 2012
    ..However, only a few studies have shed light on how the mountains and river valleys promote genetic diversity. Apodemus ilex is a fine model for investigating this subject...
  2. ncbi Allelic diversity at the Mhc-DQA locus in cotton rats (Sigmodon hispidus) and a comparison of DQA sequences within the family muridae (Mammalia: Rodentia)
    R S Pfau
    Department of Zoology 430 LSW, Oklahoma State University, Stillwater, OK 74078, USA
    Immunogenetics 49:886-93. 1999
    ..hispidus alleles. To examine evolution of DQA alleles within Muridae, we performed a phylogenetic analysis that included DQA alleles from S. hispidus, Peromyscus leucopus, M...
  3. pmc Assessment of three mitochondrial genes (16S, Cytb, CO1) for identifying species in the Praomyini tribe (Rodentia: Muridae)
    Violaine Nicolas
    Museum national d histoire naturelle, Département de Systématique et Evolution UMR CNRS 7205, Paris, France
    PLoS ONE 7:e36586. 2012
    ....
  4. doi Dental microwear patterns of extant and extinct Muridae (Rodentia, Mammalia): ecological implications
    Helder Gomes Rodrigues
    Laboratoire de Paléontologie Paléobiologie Phylogénie, Institut des Sciences de l Evolution de l Université Montpellier II, UMR CNRS 5554 Case courrier 064, Place Eugene Bataillon, 34 095, Montpellier Cedex 5, France
    Naturwissenschaften 96:537-42. 2009
    Extant species of Muridae occupy a wide array of habitats and have diverse dietary habits...
  5. ncbi Molecular phylogeny and taxonomy of wood mice (genus Apodemus Kaup, 1829) based on complete mtDNA cytochrome b sequences, with emphasis on Chinese species
    Xiaoming Liu
    Institute of Zoology, Chinese Academy of Sciences, Beijing 100080, China
    Mol Phylogenet Evol 33:1-15. 2004
    ..17-9.95 Mya. Four species of the Sylvaemus group were estimated to diverge at about 2.92-5.21 Mya. The Hengduan Mountains Region was hypothesized to have played important roles in Apodemus evolutionary histories since the Pleistocene...
  6. ncbi Testosterone depresses innate and acquired resistance to ticks in natural rodent hosts: a force for aggregated distributions of parasites
    V L Hughes
    Department of Zoology, University of Oxford, UK
    J Parasitol 87:49-54. 2001
    ..The lowest innate and acquired resistance to tick feeding occurs in that fraction of the host population, i.e., sexually active males, most actively involved in the transmission of both Babesia microti and Borrelia burgdorferi s.l...
  7. ncbi Restricted gene flow in Calomys musculinus (Rodentia, Muridae), the natural reservoir of Junin virus
    M B Chiappero
    Catedra de Bioquimica y Biologia Molecular, Facultad de Ciencias Medicas, Universidad Nacional de Cordoba, Casilla de Correo 35, Sucursal 16, 5016 Cordoba, Argentina
    J Hered 94:490-5. 2003
    ..musculinus have colonized their present ranges relatively recently and differentiation by genetic drift has proceeded faster than homogenization by gene flow at the macrogeographic scale analyzed (10-700 km)...
  8. ncbi Evolutionary conservation of whole homeologous chromosome arms in the Akodont rodents Bolomys and Akodon (Muridae, Sigmodontinae): maintenance of interstitial telomeric segments (ITBs) in recent event of centric fusion
    V Fagundes
    Departamento de Biologia, Universidade de Sao Paulo, Brazil
    Chromosome Res 6:643-8. 1998
    ..The homeologies shared between the chromosomes of these two species and those of A. cursor (2n = 16), from previous work, are discussed...
  9. ncbi A spatial aspect on mitochondrial DNA genealogy in Apodemus peninsulae from East Asia
    Keiko Serizawa
    Laboratory of Ecology and Genetics, Graduate School of Environmental Earth Science, Hokkaido University, Sapporo, Japan
    Biochem Genet 40:149-61. 2002
    ....
  10. ncbi Syphacia longaecauda n. sp. (Nematoda: Oxyuridae) syphacinea from Melomys spp. (Muridae: Hydromyinae) from Papua New Guinea and Irian Jaya, Indonesia
    L R Smales
    School of Biological and Environmental Sciences, Central Queensland University, Rockhampton, Queensland 4700, Australia
    Parasite 8:39-43. 2001
    ..The significance of the distribution of S. longaecauda, apparently restricted to New Guinea, is discussed...
  11. ncbi Mitochondrial phylogeny of African wood mice, genus Hylomyscus (Rodentia, Muridae): implications for their taxonomy and biogeography
    V Nicolas
    MNHN, Département de Systématique et Evolution, UMR 5202, Laboratoire Mammifères et Oiseaux, 55 rue Buffon, 75005 Paris, France
    Mol Phylogenet Evol 38:779-93. 2006
    ..Future reports should focus on the geographic distribution of Hylomyscus species in order to get a better understanding of the evolutionary history of the genus...
  12. ncbi Phylogeny of Neotropical oryzomyine rodents (Muridae: Sigmodontinae) based on the nuclear IRBP exon
    Marcelo Weksler
    The Graduate School and University Center, City University of New York, New York, USA
    Mol Phylogenet Evol 29:331-49. 2003
    ..No conflict is observed between IRBP results and previous robust hypotheses from mitochondrial data, while a single case of incongruence is present between the IRBP topology and robust hypothesis from morphological studies...
  13. ncbi Incidence from coincidence: patterns of tick infestations on rodents facilitate transmission of tick-borne encephalitis virus
    S E Randolph
    Department of Zoology, University of Oxford, UK
    Parasitology 118:177-86. 1999
    ..This identifies the particular climatic factors that permit such patterns of tick seasonal dynamics as the primary predictors for the focal distribution of TBE...
  14. ncbi Non-telomeric sites as evidence of chromosomal rearrangement and repetitive (TTAGGG)n arrays in heterochromatic and euchromatic regions in four species of Akodon (Rodentia, Muridae)
    K Ventura
    Departamento de Genética e Biologia Evolutiva, Instituto de Biociencias, Universidade de São Paulo Laboratório de Genética, Sao Paulo, Brazil
    Cytogenet Genome Res 115:169-75. 2006
    ....
  15. ncbi Litomosoides anguyai n. sp. (Nematoda: Onchocercidae) from Oxymycterus misionalis (Rodentia: Muridae) in the rain forest of Misiones, Argentina
    Juliana Notarnicola
    Centro de Estudios Parasitológicos y de Vectores CEPAVE, Calle 2 584 1900 La Plata, Argentina
    Syst Parasitol 52:129-35. 2002
    ..legerae and L. oxymycteri. The new species is differentiated by the salient amphids, an asymmetrical annular thickening of the buccal capsule, by the arrangement of the head and tail papillae, and the shape and size of the microfilaria...
  16. ncbi Karyotypic evolution of Apodemus (Muridae, Rodentia) inferred from comparative FISH analyses
    Kazumi Matsubara
    Laboratory of Cytogenetics, Division of Bioscience, Graduate School of Environmental Earth Science, Hokkaido University, North 10 West 8, Kita ku, Sapporo 060 0810, Japan
    Chromosome Res 12:383-95. 2004
    ..The karyotypic relationships correlated well with the molecular phylogeny, and A. semotus had the most highly conserved karyotype among the seven species...
  17. doi Molecular evolution of Trichuris muris isolated from different Muridae hosts in Europe
    Rocio Callejón
    Department of Microbiology and Parasitology, Faculty of Pharmacy, University of Seville, Profesor García González 2, Seville, Spain
    Parasitol Res 107:631-41. 2010
    A phylogeographic study was carried out of Trichuris muris, nematode parasitizing Murinae rodents from the Muridae family, isolated from four different hosts and from different geographical regions of Europe by amplification and ..
  18. ncbi Experimental infection of the cane mouse Zygodontomys brevicauda (family Muridae) with guanarito virus (Arenaviridae), the etiologic agent of Venezuelan hemorrhagic fever
    C F Fulhorst
    Department of Pathology, Center for Tropical Diseases, University of Texas Medical Branch, Galveston, TX 77555 0609, USA
    J Infect Dis 180:966-9. 1999
    ..These findings indicate that Guanarito virus infection in Z. brevicauda can be chronic and thus support the concept that this rodent species is the natural reservoir of Guanarito virus...
  19. ncbi Intra- and interspecific variation in primate gene expression patterns
    Wolfgang Enard
    Max Planck Institute for Evolutionary Anthropology, Inselstrasse 22, D 04103 Leipzig, Germany
    Science 296:340-3. 2002
    ..We identified species-specific gene expression patterns indicating that changes in protein and gene expression have been particularly pronounced in the human brain...
  20. ncbi Evolution of MHC-DRB class II polymorphism in the genus Apodemus and a comparison of DRB sequences within the family Muridae (Mammalia: Rodentia)
    Kerstin Musolf
    Department of Animal Ecology and Conservation, Biozentrum Grindel, University of Hamburg, Martin Luther King Platz 3, 20146 Hamburg, Germany
    Immunogenetics 56:420-6. 2004
    ..Phylogenetic analysis, including additional murid taxa, showed that the DRB exon 2 sequences did not separate according to species, consistent with trans-species evolution of the MHC in these taxa...
  21. pmc Phylogenomics of the genus Mus (Rodentia; Muridae): extensive genome repatterning is not restricted to the house mouse
    Frederic Veyrunes
    Institut des Sciences de l Evolution UMR5554, Génétique and Environnement, Universite Montpellier II, 34095 Montpellier Cedex 5, France
    Proc Biol Sci 273:2925-34. 2006
    ....
  22. ncbi H19 and Igf2 are expressed and differentially imprinted in neuroectoderm-derived cells in the mouse brain
    M Hemberger
    Max Planck Institut fur Molekulare Genetik, Ihnestrasse 73, D 14195 Berlin Dahlem, Germany
    Dev Genes Evol 208:393-402. 1998
    ....
  23. ncbi Chromosomal and molecular characterization of Aethomys kaiseri from Zambia and Aethomys chrysophilus from Tanzania (Rodentia, Muridae)
    Riccardo Castiglia
    Dipartimento di Biologia Animale e dell Uomo, Universita di Roma La Sapienza, Roma, Italy
    Hereditas 139:81-9. 2003
    ..49 Mya, a period of intense speciation in other African muroids. The resulting phylogeny strongly supports the idea of a paraphyletic group, suggesting the need to elevate the previously described subgenera to the genus rank...
  24. ncbi The karyotype and sex chromosomes of Praomys tullbergi (Muridae, Rodentia): a detailed characterization
    Susana Meles
    Institute for Biotechnology and Bioengineering, Centre of Genetics and Biotechnology, University of Trás os Montes and Alto Douro CGB UTAD IBB, Vila Real, Portugal
    Micron 39:559-68. 2008
    ..species, which is one of the tullbergi complex elements, a group of species belonging to Murinae (Rodentia, Muridae)...
  25. pmc The scale of mutational variation in the murid genome
    Daniel J Gaffney
    Institute of Evolutionary Biology, Ashworth Laboratories, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, United Kingdom
    Genome Res 15:1086-94. 2005
    ..This raises questions about the biological mechanism(s) that produce new mutations and has implications for the study of male-driven evolution...
  26. ncbi Epizootiology of arenaviral infections in the white-throated woodrat (Muridae: Sigmodontinae) and other woodrats in Arizona
    Ken D Abbott
    Department of Biology, Yavapai College, Prescott, AZ 86301, USA
    J Vector Ecol 29:355-64. 2004
    ....
  27. pmc PCR detection of granulocytic ehrlichiae in Ixodes ricinus ticks and wild small mammals in western Switzerland
    J S Liz
    Department of Immunology, Institute of Zoology, University of Neuchatel, 2007 Neuchatel, Switzerland
    J Clin Microbiol 38:1002-7. 2000
    ..Dual infections with granulocytic ehrlichia and Borrelia burgdorferi were found in ticks and small mammals...
  28. ncbi Phylogeny and divergence-date estimates of rapid radiations in muroid rodents based on multiple nuclear genes
    Scott Steppan
    Department of Biological Science, Florida State University, Tallahassee, Florida 32306 1100, USA
    Syst Biol 53:533-53. 2004
    ..The among-gene variance in support is greatest for the shortest branches. We present a revised classification for this largest but most unsettled mammalian superfamily...
  29. ncbi Cytochrome b-based phylogeny of the Praomys group (Rodentia, Murinae): a new African radiation?
    Emilie Lecompte
    Laboratoire Zoologie, Mammifères et Oiseaux, Museum national d histoire naturelle, 55, rue Buffon, 75005 Paris, France
    C R Biol 325:827-40. 2002
    ..The genus Heimyscus appears closest to Praomys than to Hylomyscus. The different lineages probably result from an adaptive radiation at the end of the Miocene...
  30. ncbi Mitochondrial phylogeography of the Woodmouse (Apodemus sylvaticus) in the Western Palearctic region
    J R Michaux
    Unité de recherches zoogéographiques, Institut de Zoologie, Liege, Belgium
    Mol Ecol 12:685-97. 2003
    ..Finally, woodmice in North Africa originated from southwestern Europe, most probably as a result of a recent anthropogenic introduction...
  31. pmc Rodents in open space adjust their behavioral response to the different risk levels during barn-owl attack
    Shahaf Edut
    Department of Zoology, Tel Aviv University, Ramat Aviv 69 978, Israel
    BMC Ecol 3:10. 2003
    ....
  32. ncbi Molecular genetic markers spanning mouse chromosome 10
    C A Kozak
    Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892
    Genomics 8:519-24. 1990
    ....
  33. ncbi Borrelia sinica sp. nov., a lyme disease-related Borrelia species isolated in China
    T Masuzawa
    Department of Microbiology, School of Pharmaceutical Sciences, University of Shizuoka, Japan
    Int J Syst Evol Microbiol 51:1817-24. 2001
    ..Based on these results, a new Borrelia species, Borrelia sinica sp. nov., is proposed. Strain CMN3T is the type strain of this new species...
  34. ncbi Determination of Trichuris muris from murid hosts and T. arvicolae (Nematoda) from arvicolid rodents by amplification and sequentiation of the ITS1-5.8S-ITS2 segment of the ribosomal DNA
    C Cutillas
    Department of Microbiology and Parasitology, Faculty of Pharmacy, Sevilla University, Profesor García González s n, 41012 Sevilla, Spain
    Parasitol Res 88:574-82. 2002
    ..arvicolae. This corroborates the existence of two separate Trichuris species in murid and arvicolid hosts. Furthermore, a phylogenetic analysis was carried out and endonucleases restriction maps were elaborated for both species...
  35. ncbi Leptopsyllines from Madagascar (Insecta: Siphonaptera: Ceratophyllidae): description of five new species of Paractenopsyllus Wagner, 1938
    J B Duchemin
    Unité d entomologie médicale, Institut Pasteur de Madagascar, BP 1274, Antananarivo 101, Madagascar
    Parasite 11:59-70. 2004
    ..Differences in the spatial and altitudinal distributions and host ranges allow discussion of the potential factors important in the species distribution of this genus...
  36. ncbi Phylogenetic evidence for host switching in the evolution of hantaviruses carried by Apodemus mice
    Kirill Nemirov
    Department of Virology, Haartman Institute, University of Helsinki, PO Box 21, FIN 00014, Helsinki, Finland
    Virus Res 90:207-15. 2002
    ..5 MYA). Taken together with other proposed cases of host switching, our observations suggest that these events might not be exceptional in the hantavirus evolution...
  37. pmc Evidence that rodents are a reservoir of hepatitis E virus for humans in Nepal
    Junkun He
    Walter Reed Army Institute of Research, Silver Spring, Maryland, USA
    J Clin Microbiol 40:4493-8. 2002
    ..These data prove that certain peridomestic rodents acquire HEV in the wild and suggest that cross-species transmission occurs, with rodents serving as a virus reservoir for humans...
  38. ncbi Dobrava hantavirus causes hemorrhagic fever with renal syndrome in central Europe and is carried by two different Apodemus mice species
    C Sibold
    Institute of Virology, , Humboldt University, Berlin, Germany
    J Med Virol 63:158-67. 2001
    ..flavicollis-derived strains. The results indicate that Dobrava strains from A. agrarius (DOB-Aa) vs. A. flavicollis (DOB-Af) could develop different degrees of virulence in humans...
  39. ncbi Complete nucleotide sequence of a Chilean hantavirus
    John D Meissner
    Department of Microbiology, University of Nevada, FA310 MS200, Reno, NV 89557, USA
    Virus Res 89:131-43. 2002
    ....
  40. ncbi Saaremaa hantavirus in Denmark
    Kirill Nemirov
    Department of Virology, Haartman Institute, University of Helsinki, Haartmaninkatu 3, P O Box 21, FIN 00014 Helsinki, Finland
    J Clin Virol 30:254-7. 2004
    ..We also analyzed serum samples from a patient from Lolland with a history of hantavirus-like infection, probably caused by SAAV. Thus, in addition to Puumala virus, SAAV can impose a threat for the human health in Denmark...
  41. pmc Bartonella species isolated from rodents, Greece
    Afrodite Tea
    Emerg Infect Dis 10:963-4. 2004
  42. ncbi Pancreatic-type ribonuclease 1 gene duplications in rat species
    Jean Yves F Dubois
    Department of Biochemistry, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands
    J Mol Evol 55:522-33. 2002
    ..2 Myr) and between 20 and 50 in the lines to the other sequences after divergence from Niviventer and Leopoldamys (5.5 Myr)...
  43. ncbi Distribution of hantavirus foci in Belgium
    P Heyman
    Research Laboratory for Vector Borne Diseases, Queen Astrid Military Hospital MSBT, Bruynstraat, 1, B 1120, Brussels, Belgium
    Acta Trop 84:183-8. 2002
    ..Apart from Puumala virus that was carried by Clethrionomys glareolus, 2 additional rodent species, Microtus arvalis and Apodemus sylvaticus, were found antibody- and/or RNA-positive...
  44. ncbi Cotton rats (Sigmodon hispidus) and black rats (Rattus rattus) as possible reservoirs of Leishmania spp. in Lara State, Venezuela
    Hector De Lima
    Instituto de Biomedicina, Caracas, Venezuela
    Mem Inst Oswaldo Cruz 97:169-74. 2002
    ..braziliensis in two others. The latter species was also identified in the single positive specimen of S. hispidus. The results suggested both species of animals as possible reservoirs of Leishmania sp...
  45. ncbi Characterization of the 5' and 3' untranslated regions in murine mdm2 mRNAs
    S M Mendrysa
    Department of Oncology, McArdle Laboratory for Cancer Research, University of Wisconsin Medical School, WI, Madison, USA
    Gene 264:139-46. 2001
    ..The 3' UTRs do not affect either initiation codon use or translation efficiency. Thus, the murine 5' UTR, but not the 3'UTR, influences the ratio of the two MDM2 proteins but neither UTR affects MDM2 abundance significantly...
  46. ncbi Evidence of the presence of Seoul virus in Cambodia
    Jean Marc Reynes
    Institut Pasteur du Cambodge, 5 Boulevard Monivong, BP 983, Phnom Penh, Royaume du Cambodge, Cambodia
    Microbes Infect 5:769-73. 2003
    ..However, the Cambodian Seoul virus sequences clustered within two different phylogenetic lineages, one associated with R. rattus and the other with R. norvegicus...
  47. ncbi Two new species of Nippostrongylinae (Nematoda: Trichostrongylina: Heligmonellidae) from the grey leaf-eared mouse Graomys griseoflavus (Sigmodontinae) in Argentina
    M C Digiani
    Laboratoire de Biologie Parasitaire, Protistologie et Helminthologie, et CNRS FR63, Museum national d histoire naturelle, 61, rue de Buffon, 75231 Paris, France
    Parasite 10:21-9. 2003
    ..griseoflavus, representing new host and locality records. Some additional morphological data for this species are also provided...
  48. ncbi Use of a sentinel host system to study the questing behavior of Ixodes spinipalpis and its role in the transmission of Borrelia bissettii, human granulocytic ehrlichiosis, and Babesia microti
    T R Burkot
    Division of Vector-Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado, USA
    Am J Trop Med Hyg 65:293-9. 2001
    ..It suggests the potential transmission of the agents of human granulocytic ehrlichiosis and Lyme disease to other hosts by I. spinipalpis, in regions of the western United States where Ixodes pacificus is not found...
  49. ncbi Detection of Babesia microti-like parasite in filter paper-absorbed blood of wild rodents
    Tamaki Okabayashi
    School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido, Japan
    J Vet Med Sci 64:145-7. 2002
    ..The 159-bp primary sequences of PCR products tested exhibited 97.5% and 96.8% homology with those of the human isolate in Japan and of U.S. strains of B. microti, respectively...
  50. ncbi [Description of three new species of Paractenopsyllus genus (Siphonaptera: Leptopsyllinae) from Madagascar]
    J B Duchemin
    Unité d entomologie médicale, Institut Pasteur de Madagascar, BP 1274, Antananarivo 101, Madagascar
    Parasite 11:253-60. 2004
    ..Morphological affinities between these new species and those already described provide taxonomic framework for the genus. An updated identification key is provided for the diagnosis of all the 20 Malagasy species of Leptopsyllinae...
  51. ncbi Genetic characterization of new Dobrava hantavirus isolate from Greece
    Kirill Nemirov
    Department of Virology, Haartman Institute, University of Helsinki, Finland
    J Med Virol 69:408-16. 2003
    ....
  52. ncbi Evaluation of an enzyme-linked immunosorbent assay for detection of antibodies to Junin virus in rodents
    María A Morales
    Instituto Nacional de Enfermedades Virales Humanas Dr Julio I Maiztegui, Administracion Nacional de Laboratorios e Institutos de Salud, Monteagudo 2510, 2700 Pergamino, Buenos Aires, Argentina
    J Virol Methods 103:57-66. 2002
    ..These results indicate that Junin virus IgG ELISA is the most suitable assay for detection of Junin virus antibodies in rodent samples...
  53. ncbi Changes in schizogony and drug response in two lines of rodent Plasmodium, P. berghei NK 65 and P. berghei ANKA
    T Biarnais
    Laboratoire de Biologie Parasitaire, Museum national d histoire naturelle, 61, rue Buffon, 75231 Paris, France
    Parasite 9:51-7. 2002
    ..The two strains behaved very differently, in terms of their affinity for reticulocytes, and with chloroquine activity which favours an increase in SI because only merozoites are preserved...
  54. ncbi Demonstration of chymotryptic and tryptic activities in mast cells of rodents: comparison of 17 species of the family Muridae
    H Shimizu
    Experimental Animal Center, Miyazaki Medical College, Miyazaki, 889 1692, Japan
    J Comp Pathol 125:76-9. 2001
    ..genera (Acomys, Apodemus, Cricetulus, Meriones, Millardia, Mus, Rattus, Sigmodon and Vandeleuria) of the family Muridae. MMCs with negative tryptase activity were detected only in the intestinal mucosa of six subspecies of Mus ..
  55. ncbi Comparative genetics and evolution of annexin A13 as the founder gene of vertebrate annexins
    Juan Manuel Iglesias
    Department of Biochemistry and Molecular Biology, Edificio Santiago Gaston, University of Oviedo, E 33006 Oviedo, Spain
    Mol Biol Evol 19:608-18. 2002
    ....
  56. ncbi Hyperconservation of the putative antigen recognition site of the MHC class I-b molecule TL in the subfamily Murinae: evidence that thymus leukemia antigen is an ancient mammalian gene
    Beckley K Davis
    Department of Immunology, Baylor College of Medicine, Houston, TX 77030, USA
    J Immunol 169:6890-9. 2002
    ..Our results strengthen the hypotheses that TL has evolved a specialized function and represents an ancient MHC class I-b gene...
  57. ncbi First record of Mastophorus muris (Gmelin, 1790) (Nematoda: Spiruroidea) from a wild host in South America
    M Del C Rojas
    Facultad de Ciencias Exactas y Naturales, Universidad Nacional de La Pampa, Av Uruguay 151, 6300 Santa Rosa, Argentina
    Parasite 10:375-8. 2003
    ..This indicates an expansion of the distribution range of the species, which, in the subcontinent, was hitherto restricted to domestic rodents...
  58. ncbi Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2
    D Malo
    Department of Biochemistry, McGill University, Montreal, Canada
    Genomics 10:666-72. 1991
    ..These results indicate that the three isoforms of the brain sodium channel alpha-subunit are encoded by three distinct genes that share a common ancestral origin...
  59. pmc Seasonal dynamics of Anaplasma phagocytophila in a rodent-tick (Ixodes trianguliceps) system, United Kingdom
    Kevin J Bown
    Department of Veterinary Clinical Science and Animal Husbandry, Leahurst, University of Liverpool, Chester High Road, Neston, UK
    Emerg Infect Dis 9:63-70. 2003
    ..This study confirms that woodland rodents can maintain A. phagocytophila in Great Britain in the absence of other reservoir hosts and suggests that I. trianguliceps is a competent vector...
  60. pmc cDNA structure, tissue distribution, and chromosomal localization of rat PC7, a novel mammalian proprotein convertase closest to yeast kexin-like proteinases
    N G Seidah
    Clinical Research Institute of Montreal, Canada
    Proc Natl Acad Sci U S A 93:3388-93. 1996
    ..The gene for PC7 (Pcsk7) was mapped to mouse chromosome 9 by linkage analysis of an interspecific backcross DNA panel...
  61. ncbi RNA expression and chromosomal location of the mouse long-chain acyl-CoA dehydrogenase gene
    M E Hinsdale
    Department of Comparative Medicine, School of Medicine, University of Alabama at Birmingham 35294 0019, USA
    Genomics 28:163-70. 1995
    ..Quantitative evaluation of a multitissue Northern blot showed a varied ratio of the larger transcript as compared with the smaller transcripts...
  62. ncbi Gene structure, chromosomal localization, and protein sequence of mouse CD53 (Cd53): evidence that the transmembrane 4 superfamily arose by gene duplication
    M D Wright
    MRC Cellular Immunology Unit, Sir William Dunn School of Pathology, University of Oxford, UK
    Int Immunol 5:209-16. 1993
    ....
  63. ncbi Assignment of the chromogranin A (Chga) locus to homologous regions on mouse chromosome 12 and rat chromosome 6
    D Simon-Chazottes
    Department of Medicine, University of California, San Diego 92161
    Genomics 17:252-5. 1993
    ..In each case (mouse, rat, and human), chromogranin A is in a conserved region with nearby markers including the immunoglobulin heavy chain locus...
  64. ncbi [Helminth fauna of rodents (Arvicolidae and Muridae) from the Kampinos National Park]
    Marzena Kucia
    Katedra Biologii Srodowiska Zwierzat, Zakład Zoloogii, SGGW, ul Ciszewskiego 8, 02 787 Warszawa
    Wiad Parazytol 52:127-34. 2006
    ..The aim of the study was to examine the parasite fauna of rodents living in natural environment, but in close contact with human seats (small village at the area of the natural big forest)...
  65. ncbi Species-specific changes in regulatory elements of mouse haptoglobin genes
    S Pajovic
    Department of Molecular and Cellular Biology, Roswell Park Cancer Institute, Buffalo, New York 14263
    J Biol Chem 269:2215-24. 1994
    ..domesticus and M. saxicola, but not M. caroli. The specific regulatory effects of glucocorticoid receptor, C/EBP beta, and Ets proteins were documented by co-transfection...
  66. ncbi Tail short variable: characterization of a new mouse mutant, and its possible analogy to certain human vascular disruption defects
    M J Seller
    Department of Medical and Molecular Genetics, United Medical School, Guy s Hospital, London, England
    Teratology 48:383-91. 1993
    ..It is suggested that Tsv could be a mouse model for human conditions involving transverse terminal limb defects such as Moebius and de Lange syndromes...
  67. ncbi aku, a mutation of the mouse homologous to human alkaptonuria, maps to chromosome 16
    X Montagutelli
    Unite de Genetique des Mammiferes, Institut Pasteur, Paris, France
    Genomics 19:9-11. 1994
    ..Affected mice show high levels of urinary homogentisic acid without signs of ochronosis or arthritis. This mutation has been mapped to Chr 16 close to the D16Mit4 locus, in a region of synteny with human 3q...
  68. ncbi Molecular survey of Babesia microti, Ehrlichia species and Candidatus neoehrlichia mikurensis in wild rodents from Shimane Prefecture, Japan
    Kenji Tabara
    The Shimane Prefectural Institute of Public Health and Environmental Science, Matsue, Shimane, Japan
    Microbiol Immunol 51:359-67. 2007
    ..muris in only a single positive sample. This study demonstrates the presence of several potentially important tick-borne pathogens in Shimane Prefecture and suggests the need for further study on the causative agents of FUOs...
  69. pmc Selection on silent sites in the rodent H3 histone gene family
    R W DeBry
    Department of Biological Science, Florida State University, Tallahassee 32306 2043
    Genetics 138:191-202. 1994
    ..Gene conversion between the two clusters of histone genes has not been an important force in the evolution of the H3 genes, but gene conversion appears to have had some effect within the cluster on chromosome 13...
  70. ncbi Characterization of human and mouse cartilage oligomeric matrix protein
    G Newton
    Division of Vascular Research, Brigham and Women s Hospital, Boston, Massachusetts 02115
    Genomics 24:435-9. 1994
    ..1. These data confirm and extend the known regions of homology between human and mouse chromosomes and establish that COMP, like thrombospondin-1, -2, -3, and -4, is present in the human and mouse genomes...
  71. ncbi Rat phenol-preferring sulfotransferase genes (Stp and Stp2): localization to mouse chromosomes 7 and 17
    A S Khan
    Oklahoma Medical Research Foundation, Oklahoma City 73104, USA
    Genomics 26:417-9. 1995
    ....
  72. ncbi Cloning and mapping of the mouse alpha 7-neuronal nicotinic acetylcholine receptor
    A Orr-Urtreger
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA
    Genomics 26:399-402. 1995
    ..5 +/- 1.7 cM-Gas2-0.9 cM +/- 0.9 cM-D7Mit70-1.8 +/- 1.2 cM-Acra7-4.4 +/- 1.0 cM-Hras1-ps1/Igf1r/Snrp2a. The human gene was confirmed to map to the homologous region of human chromosome 15q13-q14...
  73. ncbi Phylogenetic relationships of rodent pinworms (genus Syphacia) in Japan inferred from mitochondrial CO1 gene sequences
    Munehiro Okamoto
    Department of Laboratory Animal Science, School of Veterinary Medicine, Faculty of Agriculture, Tottori University, Tottori, USA
    J Vet Med Sci 69:545-7. 2007
    ..These facts suggest that the co-evolutionary relationship between species of the genus Syphacia and their host rodents may not so strict and host switching has probably occurred during the course of evolution...
  74. ncbi Acquisition of nonspecific Bartonella strains by the northern grasshopper mouse (Onychomys leucogaster)
    Ying Bai
    Department of Ecology and Evolutionary Biology, University of Colorado, Boulder, CO, USA
    FEMS Microbiol Ecol 61:438-48. 2007
    ....
  75. ncbi Molecular characterization and acute phase expression of the multiple Mus caroli alpha 1-acid glycoprotein (AGP) genes. Differences in glucocorticoid stimulation and regulatory elements between the rat and mouse AGP genes
    K R Prowse
    Department of Molecular and Cellular Biology, Roswell Park Cancer Institute, Buffalo, New York 14263
    J Biol Chem 265:10201-9. 1990
    ..GRE function in this mouse region was improved by introducing a point mutation that restores the rat AGP GRE consensus sequence, although the relative induction obtained was less than the wild-type rat AGP GRE...
  76. ncbi Rodent-associated Bartonella in Saskatchewan, Canada
    Claire Jardine
    Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    Vector Borne Zoonotic Dis 5:402-9. 2005
    ....
  77. ncbi The systematic position of some Ethiopian Nippostrongylinae (Nematoda, Trichostrongylina, Heligmosomoidea) from the National Collection of Animal Helminths, Onderstepoort, South Africa
    M C Durette-Desset
    Département de Systématique et Evolution, Museum national d histoire naturelle, UMR 7138 associee au CNRS, CP 52, 61 rue Buffon, 75251 Paris, France
    Onderstepoort J Vet Res 72:55-65. 2005
    ..The systematic position of Heligmonina spira (Ortlepp, 1939) and Neoheligmonella capensis (Ortlepp, 1939) is confirmed here through their synlophe, which was not previously studied...
  78. ncbi cDNA cloning and chromosomal mapping of mouse fast skeletal muscle troponin T
    A Koch
    Department of Developmental Hematology, Amgen, Incorporated, M S99 1 A, 1840 De Havilland Drive Thousand Oaks, California 91320 1789, USA
    Mamm Genome 8:346-8. 1997
  79. ncbi A HECT domain ubiquitin ligase closely related to the mammalian protein WWP1 is essential for Caenorhabditis elegans embryogenesis
    K Huang
    University of Wisconsin Medical School, Department of Pharmacology, Molecular and Cellular Pharmacology Program, 387 Medical Science Center, 1300 University Avenue, 53706, Madison, WI, USA
    Gene 252:137-45. 2000
    ..CeWWP1 must therefore have unique and nonredundant functions critical for embryogenesis...
  80. ncbi Evolutionary rate of a gene affected by chromosomal position
    J Perry
    Section of Gene Function and Regulation Chester Beatty Laboratories Institute of Cancer Research, 237 Fulham Road, London, SW3 6JB, UK
    Curr Biol 9:987-9. 1999
    ..This finding also provides support for the suggestion that regions of the genome with a high recombination frequency, such as the PAR, may have an intrinsically elevated rate of sequence divergence...
  81. ncbi Hantavirus pulmonary syndrome in Latin America
    Noemi Pini
    Research Department, National Institute of Human Viral Diseases Dr Julio I Maiztegui, Buenos Aires, Argentina
    Curr Opin Infect Dis 17:427-31. 2004
    ..This update shows the advances in the study of hantaviruses in several countries of the region and the problems that are still unresolved...
  82. ncbi Reduced nucleotide variability at an androgen-binding protein locus (Abpa) in house mice: evidence for positive natural selection
    R C Karn
    Department of Biological Sciences, Butler University, USA
    Mol Biol Evol 16:1192-7. 1999
    ..The combined observations of no variation at Abpa within M. m: domesticus and uniformly high Ka/Ks values between species suggest that positive directional selection has acted recently at this locus...
  83. ncbi Novel human and mouse annexin A10 are linked to the genome duplications during early chordate evolution
    R O Morgan
    Faculty of Medicine, University of Oviedo, Oviedo, E 33006, Spain
    Genomics 60:40-9. 1999
    ....
  84. ncbi The functional intronless S-adenosylmethionine decarboxylase gene of the mouse (Amd-2) is linked to the ornithine decarboxylase gene (Odc) on chromosome 12 and is present in distantly related species of the genus Mus
    K Persson
    Department of Cellular and Developmental Biology, Umea University, S 901 87 Umea, Sweden
    Mamm Genome 10:784-8. 1999
    ..Finally, we show that Amd-2 is present among several divergent species of the genus Mus. Thus, the integration event that generated Amd-2 may have occurred early during Mus evolution...
  85. ncbi Epizootiological and epidemiological study of hantavirus infection in Japan
    Nandadeva Lokugamage
    Laboratory of Public Health, Graduate School of Veterinary Medicine, Hokkaido University, Japan
    Microbiol Immunol 48:843-51. 2004
    ..rattus, and C. rufocanus carry hantaviruses as the reservoir animals in Japan. Infected R. rattus and R. norvegicus in port areas could be the sources of human SEOV infection and a threat to travelers and individuals working in seaports...
  86. ncbi A novel enterohepatic Helicobacter species 'Helicobacter mastomyrinus' isolated from the liver and intestine of rodents
    Zeli Shen
    Division of Comparative Medicine, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA
    Helicobacter 10:59-70. 2005
    ..A number of novel Helicobacter species have been isolated from both animals and humans. Many of these helicobacters colonize the lower gastrointestinal tract and hepatobiliary tract and are associated with diseases...
  87. pmc Identification of genetic evidence for dobrava virus spillover in rodents by nested reverse transcription (RT)-PCR and TaqMan RT-PCR
    Manfred Weidmann
    Unit for Microbiological Preparedness and Emerging Infectious Diseases, University Hospital, Stefan Meier Str 19, 79014 Freiburg, Germany
    J Clin Microbiol 43:808-12. 2005
    ..The identity of A. sylvaticus was unequivocally confirmed by random amplified polymorphic DNA analysis. The data seem to indicate hantavirus spillover from Apodemus flavicollis to other rodents...
  88. pmc Central European Dobrava Hantavirus isolate from a striped field mouse (Apodemus agrarius)
    Boris Klempa
    Institute of Virology, Helmut Ruska Haus, Charite School of Medicine, Humboldt University, D 10098 Berlin, Germany
    J Clin Microbiol 43:2756-63. 2005
    ..Most patients' sera exhibited a higher endpoint titer when probed with our new isolate, suggesting that DOBV-Aa strains are responsible for most of the DOBV-caused HFRS cases in this region...
  89. ncbi MHC diversity and the association to nematode parasitism in the yellow-necked mouse (Apodemus flavicollis)
    Y Meyer-Lucht
    Department Animal Ecology and Conservation, Biozentrum Grindel, University of Hamburg, Martin Luther King Platz 3, D 20146 Hamburg, Germany
    Mol Ecol 14:2233-43. 2005
    ..In contrast, the allele Apfl-DRB*23 showed a significant association to low FEC of the most common nematode. Thus, our results provide evidence for pathogen-driven selection acting through rare allele advantage under natural conditions...
  90. ncbi The Sycp1 loci of the mouse genome: successive retropositions of a meiotic gene during the recent evolution of the genus
    J Sage
    Unité 470, Institut National de la Sante et de la Recherche Medicale, Universite de Nice, France
    Genomics 44:118-26. 1997
    ..The two retroposition events can be dated to distinct periods in the evolution of the Muridae. Sycp1-ps2 has kept features indicative of a relatively recent origin, namely a nearly intact coding region, a ..
  91. ncbi Striped mice, Rhabdomys pumilio, and other murid rodents as hosts for immature ixodid ticks as in the Eastern Cape Province
    T N Petney
    Tick Research Unit, Rhodes Unversity, Grahamstown, 6140, South Africa
    Onderstepoort J Vet Res 71:313-8. 2004
    ..The striped mice captured in the Thomas Baines Reserve harboured considerably larger numbers of ticks than any of the rodent species in the more urbanized localities...
  92. ncbi A direct repeat sequence at the Rasgrf1 locus and imprinted expression
    R S Pearsall
    Department of Molecular and Cellular Biology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, New York, 14263 0001, USA
    Genomics 55:194-201. 1999
    ..Peromyscus animals show biallelic expression of Rasgrf1 in neonatal brain. These results suggest that direct repeat elements may play an important role in the imprinting process...
  93. ncbi Role of small mammals in the persistence of Louping-ill virus: field survey and tick co-feeding studies
    L Gilbert
    Institute of Biological Sciences, Department of Biological and Molecular Sciences, Stirling University, Stirling, UK
    Med Vet Entomol 14:277-82. 2000
    ..Here, we determine the role of small mammals, in particular field voles, Microtus agrestis L. (Muridae: Rodentia), in the persistence of LI virus on upland farms and sporting estates in Scotland, using field sampling ..
  94. ncbi Hosts and distribution of Amblyomma auricularium (Conil 1878) and Amblyomma pseudoconcolor Aragão, 1908 (Acari: Ixodidae)
    A A Guglielmone
    Estacion Experimental Agropecuaria Rafaela, Instituto Nacional de Tecnologia Agropecuaria, CC 22, CP 2300 Rafaela, Santa Fe, Argentina
    Exp Appl Acarol 29:131-9. 2003
    ..wild hosts of the families Myrmecophagidae and occasionally Didelphidae, Caviidae, Chinchillidae, Hydrochaeridae, Muridae, Canidae, Mustelidae, Procyonidae and domestic animals (cattle, dogs, horses), while A...
  95. doi Identification of potential hosts and vectors of scrub typhus and tick-borne spotted fever group rickettsiae in eastern Taiwan
    C C Kuo
    Research and Diagnostic Centre, Centres for Disease Control, Taipei, Taiwan, R O C
    Med Vet Entomol 25:169-77. 2011
    ..The striped field mouse Apodemus agrarius Pallas (Rodentia: Muridae) was the most common of the small mammals (36...
  96. ncbi Molecular evolution of the nuclear von Willebrand factor gene in mammals and the phylogeny of rodents
    D Huchon
    Laboratoire de Paléontologie, Paléobiologie et Phylogénie, Universite Montpellier II, France
    Mol Biol Evol 16:577-89. 1999
    ..10 rodent families studied here cluster in five clades: Hystricognathi, Sciuridae and Aplodontidae (Sciuroidea), Muridae, Dipodidae, and Gliridae...
  97. pmc Serologic evidence of infection with Ehrlichia spp. in wild rodents (Muridae: Sigmodontinae) in the United States
    W L Nicholson
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Clin Microbiol 36:695-700. 1998
    Rodent (Muridae: Sigmodontinae) blood and sera collected from 14 states were tested for seroreactivity to a cultured isolate of the human granulocytic ehrlichiosis (HGE) agent by using an indirect immunofluorescence assay...
  98. ncbi The phylogenetic position of "Acomyinae" (Rodentia, Mammalia) as sister group of a Murinae + Gerbillinae clade: evidence from the nuclear ribonuclease gene
    J Y Dubois
    Rijks Universiteit Groningen, Nijenborgh 4, Groningen, 9747 AG, The Netherlands
    Mol Phylogenet Evol 13:181-92. 1999
    The phylogenetic relationships of Acomys and Uranomys within Muridae were investigated using nuclear pancreatic ribonuclease A gene sequences...
  99. ncbi Phylogenetic relationships of artiodactyls and cetaceans as deduced from the comparison of cytochrome b and 12S rRNA mitochondrial sequences
    C Montgelard
    Laboratoire de Paléontologie des Vertébrés EPHE, Universite Montpellier II, France
    Mol Biol Evol 14:550-9. 1997
    ..12S rRNA support), Tylopoda, Suina, and Ancodonta, as well as Cetacea, Perissodactyla, Carnivora, Tethytheria, Muridae, and Caviomorpha...
  100. doi The gastrointestinal helminths of Lorentzimys nouhuysi (Rodentia: Muridae) with descriptions of two new genera and three new species (Nematoda) from Papua New Guinea
    L R Smales
    Parasitology Section, South Australian Museum, North Terrace, Adelaide 5000, South Australia, Australia
    J Parasitol 96:602-13. 2010
    ..The helminth assemblage of L. nouhuysi did not resemble that of any other hydromyin rodent from the region studied thus far...
  101. ncbi Consumption and mortality of the white-footed mouse (Rodentia: Muridae) and Ord's kangaroo rat (Rodentia: Heteromyidae) when fed carbaryl-bran grasshopper (Orthoptera) bait
    J R Krupovage
    New Mexico State University, Las Cruces 88003
    J Econ Entomol 83:2164-7. 1990
    ..Food preference tests disclosed that D. ordii and P. leucopus preferred natural forage rather than treated and untreated wheat bran in the laboratory...

Research Grants63

  1. MOLECULAR ANALYSIS OF CONGENITAL ANOPHTHALMIA
    Thomas Glaser; Fiscal Year: 2004
    ..regulatory sequences from the blind mole rat Spalax erhenbergi to Rx genes of mice, hamsters and other sighted Muridae; (5) collect and screen human anophthalmia cases for Rx mutations; and ( about) test the role of Rx mutahons in ..
  2. Circadian Rhythms: Photic Sensitivity and Behavior
    Roberto Refinetti; Fiscal Year: 2003
    ..abstract_text> ..
  3. ECOLOGY OF EMERGING ARENAVIRUSES IN SOUTHWESTERN U.S.
    CHARLES FULHORST; Fiscal Year: 2004
    ..S.; and, 5) investigate further the human health significance of North American rodent-borne arena viruses. ..
  4. Rapid, accurate diagnostics for arenaviral infections
    CHARLES FULHORST; Fiscal Year: 2003
    ..g., Amapari, Flexal) that were not used to develop or test the first generation assay. ..
  5. Animal models of hantavirus cardiopulmonary disease
    CHARLES FULHORST; Fiscal Year: 2006
    ..A mouse model of severe or lethal HCPS could substantively augment studies on the pathogenesis of the capillary leak that results in the life-threatening pulmonary edema HCPS. ..
  6. Viral determinants of hantavirus pulmonary disease in the hamster
    Charles F Fulhorst; Fiscal Year: 2010
    ..The plasmid-based genetic system could be used in future studies to develop vaccines to prevent infection or disease and to (in the face of clinical disease) mitigate the severity of HPS. ..
  7. Natural selection and DNA sequence variation in Mus
    MICHAEL NACHMAN; Fiscal Year: 2009
    ..domesticus and M. musculus and will provide a clear picture of the relationship between variation among commonly used inbred strains and variation in natural populations. ..
  8. Natural selection and DNA sequence variation in Mus
    Michael W Nachman; Fiscal Year: 2010
    ..domesticus and M. musculus and will provide a clear picture of the relationship between variation among commonly used inbred strains and variation in natural populations. ..
  9. Viral determinants of hantavirus pulmonary disease in the hamster
    CHARLES FULHORST; Fiscal Year: 2007
    ..The plasmid-based genetic system could be used in future studies to develop vaccines to prevent infection or disease and to (in the face of clinical disease) mitigate the severity of HPS. ..
  10. ECOLOGY OF EMERGING ARENAVIRUSES IN SOUTHWESTERN U S
    CHARLES FULHORST; Fiscal Year: 1999
    ..The project is of 3 years duration, consists of both field and laboratory studies, and involves the disciplines of virology, pathology, molecular biology, genetics, mammalogy, ecology and epidemiology. ..
  11. Evolutionary studies of mouse seminal fluid protein genes
    ROBERT KARN; Fiscal Year: 2007
    ..Furthermore, the major source of seminal fluid proteins is the prostate, a common site of male cancer. Disease research may benefit from studies of selection, since positive selection is often associated with human disease genes. ..
  12. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin Hughes; Fiscal Year: 2009
    ..In addition, by increasing our understanding of the population diversity and evolutionary history of human immune system genes, this research will enhance our knowledge of human immune function in health and disease. ..
  13. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin L Hughes; Fiscal Year: 2010
    ..In addition, by increasing our understanding of the population diversity and evolutionary history of human immune system genes, this research will enhance our knowledge of human immune function in health and disease. ..
  14. "Gdf6 gene expression and evolution in vertebrates"
    Douglas Mortlock; Fiscal Year: 2009
    ..These experiments will provide extensive insights into the conservation of this important signaling pathway gene in different animal models and the role genomic sequences play in normal skeletal patterning. ..
  15. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin Hughes; Fiscal Year: 2002
    ....
  16. PITUITARY CELLS TO STUDY MALE INFERTILITY
    STEPHEN WINTERS; Fiscal Year: 2002
    ..abstract_text> ..
  17. Retropositional or Repressor Machinery of SINEs & LINEs
    David Kass; Fiscal Year: 2002
    ....
  18. Gene Duplication and Genome Evolution
    Austin Hughes; Fiscal Year: 2004
    ..5) Examining the role of transposable elements in duplication of genomic segments by testing for nonrandom association between these elements and putatively duplicated blocks in the yeast genome. ..
  19. The Role of Sedlin in Maintaining Cartilage Integrity
    Douglas Mortlock; Fiscal Year: 2005
    ..Moreover, we anticipate that these studies will yield valuable insight into the role of the sedlin pathway in maintaining cartilage integrity and its derangement in osteoarthritis. ..
  20. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin Hughes; Fiscal Year: 2006
    ..abstract_text> ..
  21. Tissue Sensitivity to Stress in The Absence of HSP70
    Clayton Hunt; Fiscal Year: 2006
    ....
  22. A Conserved Sequence Approach for MS Association Studies
    Douglas Mortlock; Fiscal Year: 2007
    ....
  23. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin Hughes; Fiscal Year: 2007
    ..In addition, by increasing our understanding of the population diversity and evolutionary history of human immune system genes, this research will enhance our knowledge of human immune function in health and disease. ..