saimiri

Summary

Summary: A genus of the family CEBIDAE consisting of four species: S. boliviensis, S. orstedii (red-backed squirrel monkey), S. sciureus (common squirrel monkey), and S. ustus. They inhabit tropical rain forests in Central and South America. S. sciureus is used extensively in research studies.

Top Publications

  1. ncbi Update on amphetamine neurotoxicity and its relevance to the treatment of ADHD
    Claire Advokat
    Louisiana State University, Baton Rouge, LA 70803, USA
    J Atten Disord 11:8-16. 2007
  2. ncbi Rapid diagnosis and quantification of Francisella tularensis in organs of naturally infected common squirrel monkeys (Saimiri sciureus)
    Carlos Abril
    Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Langgassstrasse 122, Bern, Switzerland
    Vet Microbiol 127:203-8. 2008
  3. ncbi Numerity of a socially housed hamadryas baboon (Papio hamadryas) and a socially housed squirrel monkey (Saimiri sciureus)
    Brian R Smith
    Program in Animal Behavior, Bucknell University, Lewisburg, Pennsylvania 17837, USA
    J Comp Psychol 117:217-25. 2003
  4. ncbi Calorie restriction attenuates Alzheimer's disease type brain amyloidosis in Squirrel monkeys (Saimiri sciureus)
    Weiping Qin
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Alzheimers Dis 10:417-22. 2006
  5. ncbi Rosetting is associated with increased Plasmodium falciparum in vivo multiplication rate in the Saimiri sciureus monkey
    Cecile Le Scanf
    Institut Pasteur de la Guyane, BP 6010, 97306 Cayenne Cedex, French Guiana
    Microbes Infect 10:447-51. 2008
  6. pmc Fatty acid amide hydrolase inhibition heightens anandamide signaling without producing reinforcing effects in primates
    Zuzana Justinova
    Preclinical Pharmacology Section, Behavioral Neuroscience Research Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland, USA
    Biol Psychiatry 64:930-7. 2008
  7. ncbi Plasmodium vivax merozoite surface protein-3 contains coiled-coil motifs in an alanine-rich central domain
    M R Galinski
    Department of Medical and Molecular Parasitology, New York University School of Medicine, NY 10010, USA
    Mol Biochem Parasitol 101:131-47. 1999
  8. ncbi Optical imaging of a tactile illusion in area 3b of the primary somatosensory cortex
    Li M Chen
    Department of Neurobiology, Yale University School of Medicine, New Haven, CT 06520, USA
    Science 302:881-5. 2003
  9. ncbi Immunization of Saimiri sciureus monkeys with Plasmodium falciparum merozoite surface protein-3 and glutamate-rich protein suggests that protection is related to antibody levels
    L J M Carvalho
    Laboratory of Malaria Research, Department of Immunology, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil
    Scand J Immunol 59:363-72. 2004
  10. ncbi Anticipation of future events in squirrel monkeys (Saimiri sciureus) and rats (Rattus norvegicus): tests of the Bischof-Kohler hypothesis
    Mariam Naqshbandi
    Department of Psychology, University of Western Ontario, London, ON, Canada
    J Comp Psychol 120:345-57. 2006

Detail Information

Publications226 found, 100 shown here

  1. ncbi Update on amphetamine neurotoxicity and its relevance to the treatment of ADHD
    Claire Advokat
    Louisiana State University, Baton Rouge, LA 70803, USA
    J Atten Disord 11:8-16. 2007
    ..A review of amphetamine treatment for attention-deficit/hyperactivity disorder (ADHD) was conducted, to obtain information on the long-term neurological consequences of this therapy...
  2. ncbi Rapid diagnosis and quantification of Francisella tularensis in organs of naturally infected common squirrel monkeys (Saimiri sciureus)
    Carlos Abril
    Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Langgassstrasse 122, Bern, Switzerland
    Vet Microbiol 127:203-8. 2008
    ..tularensis bacteria per simian host cell in two common squirrel monkeys (Saimiri sciureus) from a zoo that died of tularaemia. In other organs such as the brain, F...
  3. ncbi Numerity of a socially housed hamadryas baboon (Papio hamadryas) and a socially housed squirrel monkey (Saimiri sciureus)
    Brian R Smith
    Program in Animal Behavior, Bucknell University, Lewisburg, Pennsylvania 17837, USA
    J Comp Psychol 117:217-25. 2003
    ..S. Terrace (1998, 2000), the authors trained 1 hamadryas baboon (Papio hamadryas) and 1 squirrel monkey (Saimiri sciureus) to respond to stimuli representing the numerosities 1-4 in ascending order...
  4. ncbi Calorie restriction attenuates Alzheimer's disease type brain amyloidosis in Squirrel monkeys (Saimiri sciureus)
    Weiping Qin
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Alzheimers Dis 10:417-22. 2006
    ..In this study we continued to explore the role of CR in AD-type brain amyloidosis in Squirrel monkeys (Saimiri sciureus)...
  5. ncbi Rosetting is associated with increased Plasmodium falciparum in vivo multiplication rate in the Saimiri sciureus monkey
    Cecile Le Scanf
    Institut Pasteur de la Guyane, BP 6010, 97306 Cayenne Cedex, French Guiana
    Microbes Infect 10:447-51. 2008
    ..variant (varO) of the Palo Alto line with a sibling non-rosetting variant (varR) in splenectomized Saimiri monkeys. The multiplication rate of varO parasites was 1.5-fold higher than that of the varR variant...
  6. pmc Fatty acid amide hydrolase inhibition heightens anandamide signaling without producing reinforcing effects in primates
    Zuzana Justinova
    Preclinical Pharmacology Section, Behavioral Neuroscience Research Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland, USA
    Biol Psychiatry 64:930-7. 2008
    ..To address this question, we assessed the effects of URB597, a selective anandamide deactivation inhibitor, as a reinforcer of drug-seeking and drug-taking behavior in squirrel monkeys...
  7. ncbi Plasmodium vivax merozoite surface protein-3 contains coiled-coil motifs in an alanine-rich central domain
    M R Galinski
    Department of Medical and Molecular Parasitology, New York University School of Medicine, NY 10010, USA
    Mol Biochem Parasitol 101:131-47. 1999
    ..PvMSP-3 is structurally related to P. falciparum MSP-3 and the 140000 Da MSP of P. knowlesi. Characterization of PvMSP-3, thus, also begins to define a new interspecies family of evolutionarily related Plasmodium merozoite proteins...
  8. ncbi Optical imaging of a tactile illusion in area 3b of the primary somatosensory cortex
    Li M Chen
    Department of Neurobiology, Yale University School of Medicine, New Haven, CT 06520, USA
    Science 302:881-5. 2003
    ..Thus, in contrast to traditional views of the body map, topographic representation in the SI reflects the perceived rather than the physical location of peripheral stimulation...
  9. ncbi Immunization of Saimiri sciureus monkeys with Plasmodium falciparum merozoite surface protein-3 and glutamate-rich protein suggests that protection is related to antibody levels
    L J M Carvalho
    Laboratory of Malaria Research, Department of Immunology, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil
    Scand J Immunol 59:363-72. 2004
    ..protein-3 (MSP-3) or the glutamate-rich protein (GLURP) of Plasmodium falciparum were evaluated in Saimiri sciureus monkeys...
  10. ncbi Anticipation of future events in squirrel monkeys (Saimiri sciureus) and rats (Rattus norvegicus): tests of the Bischof-Kohler hypothesis
    Mariam Naqshbandi
    Department of Psychology, University of Western Ontario, London, ON, Canada
    J Comp Psychol 120:345-57. 2006
    ..Tests of the Bischof-Kohler hypothesis were performed with squirrel monkeys (Saimiri sciureus) and rats (Rattus norvegicus)...
  11. ncbi The genome of herpesvirus saimiri C488 which is capable of transforming human T cells
    Armin Ensser
    Institut fur Klinische und Molekulare Virologie, Universitat Erlangen Nurnberg, Schlossgarten 4, D 91054 Erlangen, Germany
    Virology 314:471-87. 2003
    Herpesvirus saimiri (HVS), the rhadinovirus prototype, is apathogenic in the persistently infected natural host, the squirrel monkey, but causes acute T cell leukemia in other New World primate species...
  12. ncbi Distribution of neprilysin and deposit patterns of Abeta subtypes in the brains of aged squirrel monkeys (Saimiri sciureus)
    James K Chambers
    Laboratory of Veterinary Pathology, School of Veterinary Medicine, Azabu University, Sagamihara, Japan
    Amyloid 17:75-82. 2010
    ..We have demonstrated for the first time the distribution of NEP in the brain of a non-human primate, the squirrel monkey, which appears useful for research on AD treatment...
  13. ncbi Squirrel monkeys (Saimiri sciureus) choose smaller food arrays: long-term retention, choice with nonpreferred food, and transposition
    James R Anderson
    Department of Psychology, University of Stirling, Stirling, Scotland
    J Comp Psychol 118:58-64. 2004
    Squirrel monkeys (Saimiri sciureus) that had learned to reach toward 1 piece of food instead of 4 in a reverse-reward contingency were tested after an 8-month delay with no intervening relevant experiences...
  14. ncbi Distribution, ecology, life history, genetic variation, and risk of extinction of nonhuman primates from Costa Rica
    Maria E Zaldívar
    Universidad de Costa Rica, Escuela de Biologia, Ciudad Universitaria Rodrigo Facio, San Jose, Costa Rica
    Rev Biol Trop 52:679-93. 2004
    ..Ateles geoffroyi), howling monkeys (Alouatta palliata), capuchins (Cebus capucinus), and squirrel monkeys (Saimiri oerstedii). Geographic distribution was characterized accessing existing databases...
  15. ncbi Presence of platelet-activating factor in squirrel monkey (Saimiri boliviensis) spermatozoa: seasonal differences
    W E Roudebush
    Department of Obstetrics and Gynecology, Medical University of South Carolina, Charleston 29425 2233, USA
    Am J Primatol 45:301-5. 1998
    ..Endogenous lipids were extracted from mature Bolivian squirrel monkeys (Saimiri boliviensis) spermatozoa and assayed for the presence of PAF by [125I] radioimmunoassay...
  16. ncbi Haptic discrimination of size and texture in squirrel monkeys (Saimiri sciureus)
    P Hille
    University of Munster, Department of Psychology, Germany
    Somatosens Mot Res 18:50-61. 2001
    ..The low difference thresholds determined for the squirrel monkeys in the present study point to the significance of unrestrained test conditions for the assessment of the haptic capacity of a species...
  17. ncbi Ontogeny of limb force distribution in squirrel monkeys (Saimiri boliviensis): insights into the mechanical bases of primate hind limb dominance
    Jesse W Young
    Department of Anatomy and Neurobiology, Northeastern Ohio Medical University, Rootstown, OH 44272, USA
    J Hum Evol 62:473-85. 2012
    ..a detailed dataset of ontogenetic changes in morphology and locomotor mechanics in Bolivian squirrel monkeys (Saimiri boliviensis) was employed as a model system to evaluate each of these proposed models in turn...
  18. ncbi Genetic evidence for dispersal by both sexes in the Central American Squirrel Monkey, Saimiri oerstedii citrinellus
    M E Blair
    Department of Ecology, Evolution and Environmental Biology, Columbia University, New York, USA
    Am J Primatol 74:37-47. 2012
    ..Here, we test for SBD in an endangered New World primate, the Central American Squirrel Monkey (Saimiri oerstedii citrinellus). Previous studies of behavioral ecology suggest predominantly female dispersal in S.o...
  19. ncbi Pleistocene diversification of living squirrel monkeys (Saimiri spp.) inferred from complete mitochondrial genome sequences
    Kenneth L Chiou
    Department of Anthropology, New York University, 25 Waverly Place, New York, NY 10003, USA
    Mol Phylogenet Evol 59:736-45. 2011
    In order to enhance our understanding of the evolutionary history of squirrel monkeys (Saimiri spp.), we newly sequenced and analyzed data from seven complete mitochondrial genomes representing six squirrel monkey taxa...
  20. ncbi Telemetrically recorded neuronal activity in the inferior colliculus and bordering tegmentum during vocal communication in squirrel monkeys (Saimiri sciureus)
    Roland Tammer
    German Primate Centre, Kellnerweg 4, 37077 Gottingen, Germany
    Behav Brain Res 151:331-6. 2004
    ..The experiments were made in the squirrel monkey (Saimiri sciureus), using a telemetric extracellular recording technique which allowed to register neuronal activity in ..
  21. pmc Ontogeny of joint mechanics in squirrel monkeys (Saimiri boliviensis): functional implications for mammalian limb growth and locomotor development
    Jesse W Young
    Department of Anthropology, University of Texas at Austin, Austin, TX 78712, USA
    J Exp Biol 212:1576-91. 2009
    ..reaction forces, joint load arm lengths and external joint moments in an ontogenetic sample of squirrel monkeys (Saimiri boliviensis)...
  22. ncbi Training squirrel monkeys (Saimiri sciureus) to deceive: acquisition and analysis of behavior toward cooperative and competitive trainers
    J R Anderson
    Department of Psychology, University of Stirling, Scotland
    J Comp Psychol 115:282-93. 2001
    Three squirrel monkeys (Saimiri sciureus) learned to reach toward a container that covered food if a cooperative trainer rewarded such reaches by giving the food...
  23. ncbi Delay of gratification in capuchin monkeys (Cebus apella) and squirrel monkeys (Saimiri sciureus)
    James R Anderson
    Department of Psychology, University of Stirling, Stirling, Scotland
    J Comp Psychol 124:205-10. 2010
    In two separate series of experiments four capuchin monkeys (Cebus apella) and four squirrel monkeys (Saimiri sciureus) were given demonstration trials in which a human transferred six pieces of food, one by one, from out of each monkey'..
  24. ncbi Cranial growth in normal and low-protein-fed Saimiri. An environmental heterochrony
    Fernando V Ramirez Rozzi
    UPR 2147 Dynamique de l volution humaine CNRS, 44, rue de l Amiral Mouchez, 75014 Paris, France
    J Hum Evol 49:515-35. 2005
    ..methodologies for studying heterochrony, as well as geometric morphometrics, are used to compare two groups of Saimiri sciureus boliviensis...
  25. ncbi Living together: behavior and welfare in single and mixed species groups of capuchin (Cebus apella) and squirrel monkeys (Saimiri sciureus)
    Rebecca Leonardi
    Scottish Primate Research Group, Department of Psychology, University of Stirling, Stirling, Scotland
    Am J Primatol 72:33-47. 2010
    ..data on the behavior of single and mixed species groups of capuchin monkeys (Cebus apella) and squirrel monkeys (Saimiri sciureus) housed at the Living Links to Human Evolution Research Centre in the Royal Zoological Society of ..
  26. ncbi Plasmodium vivax merozoite surface proteins-3beta and-3gamma share structural similarities with P. vivax merozoite surface protein-3alpha and define a new gene family
    M R Galinski
    Emory University, Department of Medicine, Emory Vaccine Research Center, Yerkes Primate Research Center, 954 Gatewood Road, 30329, Atlanta, GA, USA
    Mol Biochem Parasitol 115:41-53. 2001
    ..vivax lambdagt11 clone 5.4, which was selected by immunoscreening with a Saimiri monkey antiserum. The insert DNA of this clone was used as a probe to isolate the complete gene from a P...
  27. ncbi Transient transfection of Plasmodium vivax blood stage parasites
    Judith M Pfahler
    Hygiene Institut, Abteilung Parasitologie, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 324, 69120, Heidelberg, Germany
    Mol Biochem Parasitol 149:99-101. 2006
  28. ncbi Reorganization of remote cortical regions after ischemic brain injury: a potential substrate for stroke recovery
    S B Frost
    Center on Aging, Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    J Neurophysiol 89:3205-14. 2003
    ..Reorganization in intact tissue may provide a neural substrate for adaptive motor behavior and play a critical role in postinjury recovery of function...
  29. ncbi Plasmodium vivax, P. cynomolgi, and P. knowlesi: identification of homologue proteins associated with the surface of merozoites
    J W Barnwell
    Department of Medical and Molecular Parasitology, New York University School of Medicine, 341 East 25th Street, New York, New York, 10010, USA
    Exp Parasitol 91:238-49. 1999
    ..vivax MSP mAb and the P. cynomolgi MSP rabbit antiserum significantly inhibited entry of P. vivax merozoites. We denote, on a preliminary basis, these antigenically related merozite surface proteins PvMSP-185, PcyMSP-150, and PkMSP-110...
  30. ncbi Effects of small ischemic lesions in the primary motor cortex on neurophysiological organization in ventral premotor cortex
    Numa Dancause
    Department of Neurology, University of Rochester Medical Center, 601 Elmwood Avenue, Box 673, Rochester, NY 14642, USA
    J Neurophysiol 96:3506-11. 2006
    ....
  31. ncbi Behavioral motor recovery in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned squirrel monkey (Saimiri sciureus): changes in striatal dopamine and expression of tyrosine hydroxylase and dopamine transporter proteins
    Giselle M Petzinger
    George and MaryLou Boone Parkinson s Disease and Movement Disorders Research Center, Department of Neurology, University of Southern California, Los Angeles, California
    J Neurosci Res 83:332-47. 2006
    ..In the squirrel monkey (Saimiri sciureus), MPTP-lesioning results in parkinsonian motor symptoms including bradykinesia, postural instability, ..
  32. ncbi The efficacy of combined therapy of arsenic trioxide and alpha interferon in human T-cell leukemia virus type-1-infected squirrel monkeys (Saimiri sciureus)
    Jean Michel Heraud
    Laboratoire de Retrovirologie, Institut Pasteur de la Guyane, 23, avenue Pasteur, 97306 Cayenne, French Guiana
    Antiviral Res 70:132-9. 2006
    ..study, we evaluated the toxicity and the efficacy of this combined treatment in HTLV-1-infected squirrel monkeys (Saimiri sciureus) and HTLV-1 infected cell lines derived therefrom...
  33. pmc Lymphoid organs as a major reservoir for human T-cell leukemia virus type 1 in experimentally infected squirrel monkeys (Saimiri sciureus): provirus expression, persistence, and humoral and cellular immune responses
    M Kazanji
    Unité d Oncologie Virale, Institut Pasteur, Paris, France
    J Virol 74:4860-7. 2000
    ..of human T-cell leukemia virus type 1 (HTLV-1) in various organs of serially sacrificed squirrel monkeys (Saimiri sciureus) in order to localize the reservoir of the virus and to evaluate the relationship between viral ..
  34. ncbi Mapping the minimal regions within the ORF73 protein required for herpesvirus saimiri episomal persistence
    Rhoswyn Griffiths
    Institute of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK
    J Gen Virol 89:2843-50. 2008
    Herpesvirus saimiri (HVS) establishes a persistent infection in which the viral genome persists as a circular non-integrated episome...
  35. ncbi Ovarian aging in squirrel monkeys (Saimiri sciureus)
    Margaret L Walker
    Yerkes National Primate Research Center, Emory University, Atlanta, Georgia 30329, USA
    Reproduction 138:793-9. 2009
    In female squirrel monkeys (Saimiri sciureus), the reproductive period normally extends from approximately 2.5 years to the mid-teens...
  36. ncbi A squirrel monkey model of poststroke motor recovery
    Randolph J Nudo
    Center on Aging, Department of Physiology, University of Kansas Medical Center, Kansas City, USA
    ILAR J 44:161-74. 2003
    ..This methodology is described in detail, and many of the resulting findings that are relevant for understanding stroke recovery and the effects of rehabilitative and pharmacotherapeutic interventions are summarized...
  37. ncbi Social organization of a stable natal group of captive Guyanese squirrel monkeys (Saimiri sciureus sciureus)
    Meredith J Bashaw
    Psychology Department, Franklin and Marshall College, PO Box 3003, Lancaster, PA, 17604 3003, USA
    Primates 52:361-71. 2011
    ..Wild populations of squirrel monkeys (Saimiri spp.) appear to conform to the predictions of the predation/competition socioecological model (Sterck et al...
  38. pmc Pathologic modifications of alpha-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated squirrel monkeys
    Alison L McCormack
    The Parkinson s Institute, Sunnyvale, California 94085, USA
    J Neuropathol Exp Neurol 67:793-802. 2008
    ..The findings are also consistent with a pattern of evolution of alpha-synuclein pathology that may begin with the accumulation and aggregation of the protein within damaged axons...
  39. pmc Immunogenicity and protective efficacy of recombinant human T-cell leukemia/lymphoma virus type 1 NYVAC and naked DNA vaccine candidates in squirrel monkeys (Saimiri sciureus)
    M Kazanji
    Laboratoire de Retrovirologie, Institut Pasteur de la Guyane, 23 Av Pasteur, Cayenne, French Guiana
    J Virol 75:5939-48. 2001
    ....
  40. ncbi Isolation and characterization of brain microvascular endothelial cells from Saimiri monkeys. An in vitro model for sequestration of Plasmodium falciparum-infected erythrocytes
    F Gay
    Unite de Parasitologie Experimentale, Institut Pasteur de Lyon, Lentilly, France
    J Immunol Methods 184:15-28. 1995
    ..Previously, we have shown that the squirrel monkey Saimiri sciureus is a potential model for human cerebral malaria...
  41. ncbi Optical imaging of intrinsic signals in somatosensory cortex
    Mark Tommerdahl
    Department of Biomedical Engineering, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Behav Brain Res 135:83-91. 2002
    ..g. Physiol. Behav. 5 (1970) 1431) when oscillatory tactile stimuli are used...
  42. ncbi Extensive cortical rewiring after brain injury
    Numa Dancause
    Department of Molecular and Integrative Physiology, The University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    J Neurosci 25:10167-79. 2005
    ..Our results reveal an extraordinary anatomical rewiring capacity in the adult CNS after injury that may potentially play a role in recovery...
  43. ncbi Fine-scale organization of SI (area 3b) in the squirrel monkey revealed with intrinsic optical imaging
    L M Chen
    Section of Neurobiology, Yale University School of Medicine, New Haven, Connecticut 06520-8051, USA
    J Neurophysiol 86:3011-29. 2001
    ..the somatotopic map and the representation of pressure, flutter, and vibration in area 3b of the squirrel monkey (Saimiri sciureus) cortex under pentothal or isoflurane anesthesia...
  44. ncbi Transmission of human spongiform encephalopathies to experimental animals: comparison of the chimpanzee and squirrel monkey
    D M Asher
    Laboratory of Central Nervous System Studies, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20992
    Dev Biol Stand 80:9-13. 1993
    ..No other animals have been found so consistently susceptible to the agents in human tissues. More rapid and convenient assays for the infectious agents would greatly facilitate research on the spongiform encephalopathies of humans...
  45. pmc Interspecies transmission of chronic wasting disease prions to squirrel monkeys (Saimiri sciureus)
    Richard F Marsh
    Department of Medical Microbiology and Immunology, Creighton University, 2500 California Plaza, Omaha, NE 68178, USA
    J Virol 79:13794-6. 2005
    ..Brain tissue from the CWD-infected squirrel monkeys contained the abnormal isoform of the prion protein, PrP-res, and displayed spongiform degeneration. This is the first reported transmission of CWD to primates...
  46. ncbi DNA evidence on the phylogenetic systematics of New World monkeys: support for the sister-grouping of Cebus and Saimiri from two unlinked nuclear genes
    M L Harada
    Universidade Federal do Para, Departamento de Genetica, Belem, Brazil
    Mol Phylogenet Evol 4:331-49. 1995
    ..for the clades in the most parsimonious trees found: for this epsilon data set enlarged with additional Cebus and Saimiri orthologues; for another nuclear DNA sequence data set consisting of IRBP (interstitial retinol-binding protein ..
  47. ncbi Self-administration of delta9-tetrahydrocannabinol (THC) by drug naive squirrel monkeys
    Zuzana Justinova
    Preclinical Pharmacology Section, Behavioral Neuroscience Research Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Baltimore, MD 21224, USA
    Psychopharmacology (Berl) 169:135-40. 2003
    ....
  48. ncbi Cortical synaptic arrangements of the third visual pathway in three primate species: Macaca mulatta, Saimiri sciureus, and Aotus trivirgatus
    Yuri Shostak
    Department of Cell Biology, Vanderbilt University, Nashville, Tennessee 37232 2175, USA
    J Neurosci 22:2885-93. 2002
    ..The basic similarities between K axon circuitry within the CO blobs of the three primate species examined also could indicate that this pathway plays some common role or roles across species...
  49. ncbi Molecular cloning, characterization, and quantification of squirrel monkey ( Saimiri sciureus) Th1 and Th2 cytokines
    Jean Michel Heraud
    Laboratoire de Retrovirologie, Institut Pasteur de la Guyane, BP 6010, 23, avenue Pasteur, 97300 Cayenne, French Guiana
    Immunogenetics 54:20-9. 2002
    Primates have long been used as models to study the basic mechanisms of human disease. The squirrel monkey, Saimiri sciureus,is a New World monkey that can be satisfactorily bred in captivity and infected with various human pathogens...
  50. ncbi Sequencing and analysis of genomic DNA and cDNA encoding TNF-alpha in the squirrel monkey (Saimiri sciureus)
    Fabrice Merien
    Centre de Primatologie, Institut Pasteur de la Guyane, BP 6010, 97306 Cayenne Cedex, French Guiana
    Vet Immunol Immunopathol 92:37-43. 2003
    ..The corresponding cDNA is 702 nucleotides and phylogenetic analysis showed that the Saimiri sciureus was most closely related to that of the genus Aotus, a new-world primate, compared to old-world primates ..
  51. ncbi Acute reductions in GABAA receptor binding in layer IV of adult primate somatosensory cortex after peripheral nerve injury
    C L Wellman
    Department of Psychology, Program in Neural Science, Indiana University, Bloomington, IN 47405, USA
    Brain Res 954:68-72. 2002
    ..Here we report reductions in GABA(A) receptor binding in layer IV of primate somatosensory cortex deprived of its normal activating inputs for 2-5 h by peripheral nerve transection...
  52. pmc Novel gamma-1 herpesviruses identified in free-ranging new world monkeys (golden-handed tamarin [Saguinus midas], squirrel monkey [Saimiri sciureus], and white-faced saki [Pithecia pithecia]) in French Guiana
    Benoit de Thoisy
    Laboratoire de Retrovirologie, Institut Pasteur de la Guyane, Cayenne, French Guiana
    J Virol 77:9099-105. 2003
    ..lymphocryptoviruses from golden-handed tamarin (Saguinus midas) of the Callitrichidae family and squirrel monkey (Saimiri sciureus) and white-faced saki (Pithecia pithecia) of the Cebidae family...
  53. ncbi Genetic analysis of the Saimiri breeding colony of the Pasteur Institute (French Guiana): development of a molecular typing method using a combination of nuclear and mitochondrial DNA markers
    Anne Lavergne
    Centre de Primatologie, Institut Pasteur, Cayenne, Guyane Francaise, Universite de Montpellier II, Pl E Bataillon, Montpellier Cedex 5, France
    J Med Primatol 32:330-40. 2003
    b>Saimiri (Cebidae) groups a complex of species and subspecies, which present a large morphological plasticity...
  54. ncbi The composition of milk from Bolivian squirrel monkeys (Saimiri boliviensis boliviensis)
    Lauren A Milligan
    Department of Anthropology, University of Arizona, Tucson, Arizona, USA
    Am J Primatol 70:35-43. 2008
    Squirrel monkeys (genus Saimiri) give birth to relatively large neonates with large, fast-growing brains...
  55. ncbi Meiotic characterization and sex determination system of neotropical primates: Bolivian squirrel monkey Saimiri boliviensis (primates: Cebidae)
    Eliana R Steinberg
    Grupo de Investigación en Biología Evolutiva GIBE, CONICET, Departamento de Ecologia, Genetica y Evolucion, Universidad de Buenos Aires, Ciudad Universitaria, Pab II, 4 degrees Piso, Lab 46, 1428EHA, Buenos Aires, Argentina
    Am J Primatol 69:1236-41. 2007
    ..The goal of this study was to characterize the sex determination system of Saimiri boliviensis...
  56. ncbi Clinical, neuropathological and immunohistochemical features of sporadic and variant forms of Creutzfeldt-Jakob disease in the squirrel monkey (Saimiri sciureus)
    Lawrence Williams
    Department of Veterinary Sciences, Michale E Keeling Center for Comparative Medicine and Research, University of Texas MD Anderson Cancer Center, Bastrop, TX, USA
    J Gen Virol 88:688-95. 2007
    The squirrel monkey (Saimiri sciureus) has been shown to be nearly as susceptible as the chimpanzee to experimentally induced Creutzfeldt-Jakob disease (CJD), and has been used extensively in diagnostic and pathogenetic studies...
  57. ncbi Modeling dichromatic and trichromatic sensitivity to the color properties of fruits eaten by squirrel monkeys (Saimiri sciureus)
    Mariana F P De Araújo
    Laboratório de Neurociências e Comportamento, CFS, IB, Universidade de Brasilia, Brazil
    Am J Primatol 68:1129-37. 2006
    ..In this study the reflectance spectra of fruits and flowers eaten by a troop of squirrel monkeys (Saimiri sciureus) in Eastern Amazon were measured using a spectrophotometer. S...
  58. ncbi Topographically divergent and convergent connectivity between premotor and primary motor cortex
    Numa Dancause
    Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, KS 66160, USA
    Cereb Cortex 16:1057-68. 2006
    ..To our knowledge, this is the first description of such a consistent clustering of PMv terminals within M1...
  59. ncbi Plasmodium simium and Saimiri boliviensis as a model system for testing candidate vaccines against Plasmodium vivax
    William E Collins
    Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Am J Trop Med Hyg 73:644-8. 2005
    Observations on Plasmodium simium infections in Saimiri boliviensis boliviensis monkeys suggest that this host-parasite combination would be a suitable model for the testing of candidate vaccines against Plasmodium vivax...
  60. ncbi Alpha-synuclein expression in the substantia nigra of MPTP-lesioned non-human primates
    Maya G Purisai
    The Parkinson s Institute, 1170 Morse Avenue, Sunnyvale, California 94089, USA
    Neurobiol Dis 20:898-906. 2005
    ..They support a direct relationship between neuronal injury and enhanced alpha-synuclein expression, and suggest that protein elevation within cell bodies may be a late feature of neurons that have endured a toxic stress...
  61. ncbi Quadrupedal locomotion in squirrel monkeys (Cebidae: Saimiri sciureus): a cineradiographic study of limb kinematics and related substrate reaction forces
    Manuela Schmidt
    Institut für Spezielle Zoologie und Evolutionsbiologie mit Phyletischem Museum, Friedrich Schiller Universitat, 07743 Jena, Germany
    Am J Phys Anthropol 128:359-70. 2005
    ..Phys. Anthropol. 67:335-349; [1985] Am. J. Phys. Anthropol. 67:351-362), is supported by the high correlation of ratios between forelimb and hindlimb peak vertical forces and the range of motion of shoulder joint and scapula in primates...
  62. pmc Immunization of Saimiri sciureus monkeys with a recombinant hybrid protein derived from the Plasmodium falciparum antigen glutamate-rich protein and merozoite surface protein 3 can induce partial protection with Freund and Montanide ISA720 adjuvants
    Leonardo J M Carvalho
    Laboratory of Malaria Research, Department of Immunology, Instituto Oswaldo Cruz FIOCRUZ, Pavilhao Leonidas Deane, Av Brasil 4365, Manguinhos, Rio de Janeiro, RJ Brazil 21045 900
    Clin Diagn Lab Immunol 12:242-8. 2005
    ..and the C-terminal portion of the merozoite surface protein 3 (MSP3) of Plasmodium falciparum was evaluated in Saimiri sciureus monkeys...
  63. ncbi Characterization of the Herpesvirus saimiri Orf51 protein
    Robert E Means
    Department of Pathology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA
    Virology 326:67-78. 2004
    Herpesvirus saimiri (HVS) is a gamma(2)-herpesvirus sharing genomic colinearity and a high degree of functional homology with HHV-8...
  64. ncbi Immunocytochemistry of oculomotor afferents in the squirrel monkey (Saimiri sciureus)
    M B Carpenter
    Department of Anatomy, , Uniformed Services University of the Health Sciences, Bethesda, Maryland
    J Hirnforsch 33:151-67. 1992
    ..No other GLU- or ASP-positive neurons were immunoreactive for GABA, 5-HT or CCK, but cells of the lateral vestibular nucleus were surrounded by CCK-IR fibers and terminals...
  65. ncbi Aging of the nigrostriatal system in the squirrel monkey
    Alison L McCormack
    The Parkinson s Institute, Sunnyvale, California 94089, USA
    J Comp Neurol 471:387-95. 2004
    ..NM content appears to be an important marker of these age-related effects...
  66. ncbi Phylogeny and phylogeography of squirrel monkeys (genus Saimiri) based on cytochrome b genetic analysis
    Anne Lavergne
    Centre de Primatologie de l Institut Pasteur de la Guyane, Cayenne, French Guiana
    Am J Primatol 72:242-53. 2010
    Squirrel monkeys (genus Saimiri) are distributed over a wide area encompassing the Amazon Basin: French Guiana, Suriname, and Guyana, together with Western Panama and Western Costa Rica...
  67. ncbi Somatotopic reorganization in the brainstem and thalamus following peripheral nerve injury in adult primates
    J D Churchill
    Program in Neural Science, Department of Psychology, Indiana University, Bloomington, IN 47405, USA
    Brain Res 910:142-52. 2001
    ..These observations are consistent with those previously reported in thalamus, and are unique for brainstem...
  68. ncbi Object permanence in orangutans (Pongo pygmaeus) and squirrel monkeys (Saimiri sciureus)
    S T de Blois
    Department of Psychology, University of Massachusetts at Amherst, USA
    J Comp Psychol 112:137-52. 1998
    The authors tested orangutans (Pongo pygmaeus) and squirrel monkeys (Saimiri sciureus) on object permanence tasks...
  69. pmc Testing of Plasmodium vivax CS proteins in Saimiri monkeys
    W E Collins
    Malaria Branch, Centers for Disease Control, Atlanta, GA 30333
    Bull World Health Organ 68:42-6. 1990
    ..the circumsporozoite (CS) protein of Plasmodium vivax were tested for safety, immunogenicity, and efficacy in Saimiri sciureus boliviensis monkeys...
  70. pmc Two-step nature of human T-cell leukemia virus type 1 replication in experimentally infected squirrel monkeys (Saimiri sciureus)
    F Mortreux
    , Institut de Recherche sur le Cancer de Lille, Lille, France
    J Virol 75:1083-9. 2001
    After experimental infection of squirrel monkeys (Saimiri sciureus) with human T-cell leukemia virus type 1 (HTLV-1)-infected cells, the virus is transcribed only transiently in circulating blood, spleen, and lymph nodes...
  71. ncbi Human spongiform encephalopathy: the National Institutes of Health series of 300 cases of experimentally transmitted disease
    P Brown
    Laboratory of CNS Studies, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892
    Ann Neurol 35:513-29. 1994
    ....
  72. ncbi Growth of skeletal components in the young squirrel monkey (Saimiri sciureus boliviensis): a longitudinal experiment
    H M Pucciarelli
    Consejo Nacional de Investigaciones Cientificas y Tecnicas CONICET, Universidad Nacional de La Plata, 1900 La Plata, Argentina
    Am J Phys Anthropol 112:57-68. 2000
    ..The acceptance of the hypothesis will imply that all Saimiri skeletal growth may be satisfactorily explained by independent variables in a single equation...
  73. ncbi Detection of squirrel monkey retroviral sequences in interferon samples
    M Pienkowska
    Laboratory of Molecular Pathology, Women s College Hospital, Toronto, Ontario, Canada
    J Hepatol 28:396-403. 1998
    ..However, it remains to be determined whether the residual DNA sequences detected by our sensitive nested polymerase chain reaction assay have biological consequences...
  74. pmc Interhemispheric connections of the ventral premotor cortex in a new world primate
    Numa Dancause
    Department of Neurology, University of Rochester Medical Center, Rochester, New York 14642, USA
    J Comp Neurol 505:701-15. 2007
    ..They help to provide an anatomical foundation for understanding PMv's role in motor control of the hand and interhemispheric interactions that may underlie the coordination of bimanual movements...
  75. ncbi HTLV type 1 infection in squirrel monkeys (Saimiri sciureus): a promising animal model for HTLV type 1 human infection
    M Kazanji
    Laboratoire de Retrovirologie, Institut Pasteur de la Guyane, 97306 Cayenne, French Guiana
    AIDS Res Hum Retroviruses 16:1741-6. 2000
    We show that the squirrel monkey Saimiri sciureus is susceptible to experimental infection with either syngeneic or allogeneic HTLV-1-immortalized cells...
  76. ncbi Time-dependence of SI RA neuron response to cutaneous flutter stimulation
    B L Whitsel
    Department of Diagnostic Sciences, School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Somatosens Mot Res 20:45-69. 2003
    ..Parallels with recent proposals about the contributions to visual perception of short-term primary sensory cortical neuron dynamics and synchrony in multineuron spike activity patterns are identified and discussed...
  77. ncbi Laryngeal biomechanics and vocal communication in the squirrel monkey (Saimiri boliviensis)
    Charles H Brown
    Department of Psychology, University of South Alabama, Mobile, Alabama 36688, USA
    J Acoust Soc Am 113:2114-26. 2003
    ..In regime 4, the period of each oscillation was quasi-irregular. Shrieks and other broadband calls or call elements that lack an apparent fundamental frequency may be produced in this manner...
  78. ncbi Evaluation of immunogenicity and protective efficacy of carrier-free Plasmodium falciparum R23 antigen in pre-exposed saimiri sciureus monkeys
    R Perraut
    Unite d immunologie, Institut Pasteur de Dakar, BP 220, Dakar, Senegal
    Vaccine 19:59-67. 2000
    ..recombinant Glutathione S-transferase GTR23, induced protection after immunisation of naive or previously exposed Saimiri monkeys...
  79. pmc Ipsilateral connections of the ventral premotor cortex in a new world primate
    Numa Dancause
    Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    J Comp Neurol 495:374-90. 2006
    ..No statistical difference between the proportions of inputs and outputs for any location was observed, supporting the reciprocity of PMv intracortical connections...
  80. ncbi Chimeric peptide vaccine composed of B- and T-cell epitopes of human T-cell leukemia virus type 1 induces humoral and cellular immune responses and reduces the proviral load in immunized squirrel monkeys (Saimiri sciureus)
    Mirdad Kazanji
    Laboratoire de Retrovirologie, Institut Pasteur de la Guyane, French Guiana
    J Gen Virol 87:1331-7. 2006
    ..After challenge, it was shown by competitive PCR that partial protection against HTLV-1 infection could be raised in immunized animals. Further studies should be developed to determine the duration of this protection...
  81. ncbi Anatomic correlates of the face and oral cavity representations in the somatosensory cortical area 3b of monkeys
    N Jain
    Department of Psychology, Vanderbilt University, Nashville, Tennessee 37240, USA
    J Comp Neurol 429:455-68. 2001
    ....
  82. ncbi Subcellular and subsynaptic localization of presynaptic and postsynaptic kainate receptor subunits in the monkey striatum
    J Z Kieval
    Division of Neuroscience, Yerkes Regional Primate Research Center, and Department of Neurology, Emory University, Atlanta, Georgia 30322, USA
    J Neurosci 21:8746-57. 2001
    ....
  83. ncbi The chemo- and somatotopic architecture of the Galago cuneate and gracile nuclei
    F Strata
    Department of Psychology, Vanderbilt University, Nashville, TN 37203, USA
    Neuroscience 116:831-50. 2003
    ..In conclusion, the different pattern of segregation of the inputs from the hand and from the foot can be related to the different metabolic organization of the cuneate and of the gracile, respectively...
  84. ncbi Neuronal activity in the inferior colliculus and bordering structures during vocalization in the squirrel monkey
    Florian Pieper
    German Primate Center, Kellnerweg 4, 37077, Gottingen, Germany
    Brain Res 979:153-64. 2003
    In four squirrel monkeys (Saimiri sciureus), the inferior colliculus, together with the neighboring superior colliculus, reticular formation, cuneiform nucleus and parabrachial area, were explored with microelectrodes, looking for ..
  85. ncbi Localization of a vocal pattern generator in the pontine brainstem of the squirrel monkey
    Steffen R Hage
    Department of Neurobiology, German Primate Center, Kellnerweg 4, 37077 Gottingen, Germany
    Eur J Neurosci 23:840-4. 2006
    ..Based on these findings and previously reported anatomical data, we propose that this area serves as a vocal pattern generator for frequency-modulated call types...
  86. ncbi Neuroscience. Illusions and perceived images in the primate brain
    Ulf T Eysel
    Department of Neurophysiology, Ruhr University Bochum, Bochum 44780, Germany
    Science 302:789-91. 2003
  87. ncbi Quantification of cerebral blood flow in nonhuman primates using arterial spin labeling and a two-compartment model
    Anne Catherin Zappe
    Department of Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, 72076 Tubingen, Germany
    Magn Reson Imaging 25:775-83. 2007
    ..The CBF values in the occipital lobe of the monkey brain quantified with ASL are higher than previously reported in positron emission tomography studies...
  88. ncbi Contribution of GABAA receptor subtypes to the anxiolytic-like, motor, and discriminative stimulus effects of benzodiazepines: studies with the functionally selective ligand SL651498 [6-fluoro-9-methyl-2-phenyl-4-(pyrrolidin-1-yl-carbonyl)-2,9-dihydro-1H-
    Stephanie C Licata
    Harvard Medical School, New England Primate Research Center, Southborough, MA 01772, USA
    J Pharmacol Exp Ther 313:1118-25. 2005
    ..Moreover, a compound with reduced efficacy at alpha(1) GABA(A) and/or alpha(5) GABA(A) receptors may lack some of the motor and subjective effects associated with conventional BZs...
  89. ncbi Enhanced striatal opioid receptor-mediated G-protein activation in L-DOPA-treated dyskinetic monkeys
    L Chen
    The Parkinson s Institute, Basic Research Department, 1170 Morse Avenue, Sunnyvale, CA 94089, USA
    Neuroscience 132:409-20. 2005
    ..The positive correlation with LIDs suggests this may represent an intracellular signaling mechanism underlying these movement abnormalities...
  90. pmc Differential restriction of human immunodeficiency virus type 2 and simian immunodeficiency virus SIVmac by TRIM5alpha alleles
    Laura M J Ylinen
    Wohl Virion Center, Division of Infection and Immunity, Windeyer Building, University College London, 46 Cleveland St, London W1T4JF, United Kingdom
    J Virol 79:11580-7. 2005
    ..We map the determinant for TRIM5alpha sensitivity to the structure in the capsid protein that recruits CypA into HIV-1 virions. We also make an SIV, mutated at this site, which bypasses restriction in all cells tested...
  91. ncbi CART peptide-immunoreactive neurones in the nucleus accumbens in monkeys: ultrastructural analysis, colocalization studies, and synaptic interactions with dopaminergic afferents
    Y Smith
    Yerkes Regional Primate Research Center, Department of Neurology, Emory University, Atlanta, Georgia 30322, USA
    J Comp Neurol 407:491-511. 1999
    ....
  92. ncbi The Plasmodium vivax homologues of merozoite surface proteins 4 and 5 from Plasmodium falciparum are expressed at different locations in the merozoite
    Casilda G Black
    Department of Microbiology, Monash University, PO Box 53, Calyton 3800 Victoria, Australia
    Mol Biochem Parasitol 120:215-24. 2002
    ..vivax merozoites, as expected, whereas, the MSP5 homologue was found to be associated with an apical organellar location consistent with micronemes or over the polar prominence...
  93. ncbi TRIM5alpha association with cytoplasmic bodies is not required for antiretroviral activity
    Byeongwoon Song
    Department of Cancer Immunology and AIDS, Dana Farber Cancer Institute, Division of AIDS, Harvard Medical School, Boston, MA 02115, USA
    Virology 343:201-11. 2005
    ..Apparently, the formation of cytoplasmic bodies is not required for the antiretroviral activity of TRIM5alpha...
  94. ncbi Group I metabotropic glutamate receptors in the monkey striatum: subsynaptic association with glutamatergic and dopaminergic afferents
    Maryse Paquet
    Yerkes National Primate Research Center and Department of Neurology, Emory University, Atlanta, Georgia 30322, USA
    J Neurosci 23:7659-69. 2003
    ....
  95. pmc Firing behaviour of squirrel monkey eye movement-related vestibular nucleus neurons during gaze saccades
    Robert A McCrea
    Department of Neurobiology, Pharmacology and Physiology, Committee on Neurobiology, University of Chicago, 5806 South Ellis Avenue, Chicago, IL 60637, USA
    J Physiol 546:207-24. 2003
    ..The convergence of motor and sensory reafferent inputs on VOR pathways provides a mechanism for separate control of eye and head movements during and after saccadic gaze shifts...
  96. ncbi Severe dopaminergic neurotoxicity in primates after a common recreational dose regimen of MDMA ("ecstasy")
    George A Ricaurte
    Department of Neurology, Johns Hopkins Bayview Medical Center, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
    Science 297:2260-3. 2002
    ....
  97. ncbi Species differences in tachykinin receptor distribution: further evidence that the substance P (NK1) receptor predominates in human brain
    Michael Rigby
    In Vivo Neuroscience, Merck Sharp and Dohme Research Laboratories, Neuroscience Research Centre, Terlings Park, Harlow, Essex CM20 2QR, United Kingdom
    J Comp Neurol 490:335-53. 2005
    ..These findings demonstrate that the NK1 receptor is the predominant tachykinin receptor expressed in primate and human brain, but that low levels of NK3 receptor are present in nonhuman, primate brain...
  98. ncbi Interspecies in vitro metabolism of the phosphodiesterase-4 (PDE4) inhibitor L-454,560
    Kevin P Bateman
    Merck Frosst Centre for Therapeutic Research, 16711 Trans Canada Highway, Pointe Claire Dorval, Kirkland, Quebec, Canada
    J Mass Spectrom 41:771-80. 2006
    ..No major species differences were found in terms of microsomal metabolite profiles. The use of LC with UV and MS detection is highlighted, as well as information from tandem mass spectrometry and NMR...
  99. ncbi Neurokinin-1 and neurokinin-3 receptors in primate substantia nigra
    Martin Levesque
    Centre de Recherche Université Laval Robert Giffard 2601, chemin de la Canardiere, Local F 6500 Beauport, Quebec, Canada
    Neurosci Res 57:362-71. 2007
    ....
  100. ncbi Detecting danger--or just another odorant? Olfactory sensitivity for the fox odor component 2,4,5-trimethylthiazoline in four species of mammals
    Matthias Laska
    Department of Medical Psychology, University of Munich Medical School, Goethestr 31, D 80336 Munich, Germany
    Physiol Behav 84:211-5. 2005
    ..Thus, these results support the assumption that the behavioral relevance of an odorant may be an important determinant of a species' olfactory sensitivity...
  101. ncbi Chronic oral nicotine treatment protects against striatal degeneration in MPTP-treated primates
    Maryka Quik
    The Parkinson s Institute, Sunnyvale, California, USA
    J Neurochem 98:1866-75. 2006
    ..These data further support the possibility that nicotine contributes to the lower incidence of Parkinson's disease in smokers...

Research Grants63

  1. Conference Support for International Congress on Oncogenic Herpesviruses
    Paul M Lieberman; Fiscal Year: 2012
    ..In addition to EBV and KSHV, studies related to herpesvirus saimiri (HVS), murine herpesvirus-68 (MHV-68), rhesus rhadinovirus (RRV), and rhesus lymphocryptovirus (rhLCV) will be ..
  2. Vaccination with purified, cryopreserved, infectious Plasmodium vivax sporozoites
    STEPHEN LEV HOFFMAN; Fiscal Year: 2013
    ..before manufacturing cGMP-compliant material for clinical trials, we propose to assess the protective efficacy in Saimiri boliviensis monkeys of PvSPZ-CVac...
  3. FUNCTIONAL ORGANIZATION OF PRIMARY AUDITORY CORTEX
    Christoph E Schreiner; Fiscal Year: 2013
    ..the organization of two primary auditory fields in adult carnivores (Felis catus) and the awake squirrel monkey (Saimiri sciureus) with specific reference to functional domains and laminar organization...
  4. Testing of Innate Immunity Stimulation via TLR9 on CAA using Non-human Primates.
    Henrieta Scholtzova; Fiscal Year: 2013
    ..in a more biologically proximate and well established non-human primate model of sporadic CAA, squirrel monkey (Saimiri Boliviensis) and to begin treatment at a point where CAA is already present...
  5. Conference Support for 16th International Workshop on KSHV and Related Agents, Pu
    Bala Chandran; Fiscal Year: 2013
    ..Barr virus) and those infecting animals, such as murine herpesvirus- 68, rhesus rhadinovirus and herpesvirus saimiri. The meeting will run for four days and will cover aspects such as clinical settings, epidemiology, pathology, ..
  6. 14th International Workshop on Kaposi's Sarcoma-Associated Herpesvirus and Relate
    Dean H Kedes; Fiscal Year: 2011
    ..Barr virus) and those infecting animals, such as murine herpesvirus- 68, rhesus rhadinovirus and herpes virus saimiri. The meeting will run for four days and will cover aspects such as molecular biology, molecular mechanisms of ..
  7. SEVENTEENTH INTERNATIONAL HERPESVIRUS WORKSHOP
    S Hayward; Fiscal Year: 1992
    ..In addition simian herpesvirus saimiri and Marek's disease virus provide model systems for studying herpesvirus oncogenicity...
  8. Conference Support: NHP Models of Aging
    Joseph Kemnitz; Fiscal Year: 2001
    ..consist of presentations on microcebus (Microcebus murinus), marmosets (Callithrix jacchus), squirrel monkeys (Saimiri sciureus), cynomolgus monkeys (Macaca fascicularis), baboons (Papio hamadryas), and chimpanzees (Pan troglodytes)...
  9. Physipatogenesis of malaria anemia in humans & monkeys
    Socrates Herrera; Fiscal Year: 2005
    ..c) A primate center with both Aotus and Saimiri monkeys. d) Two third-level hospitals located in Cali...
  10. NUTRITIONAL INFLUENCES ON COLON CANCER IN THE TAMARIN
    Lynne Ausman; Fiscal Year: 1991
    ..In a second study, 12 Sgo, 12 Saguinus fuscicollis (Sgf), and 8 Saimiri sciureus will be fed diets varying the amount and type fo fat for 6 month periods...
  11. 15TH INTERNATIONAL HERPESVIRUS WORKSHOP
    LEONARD ROSENTHAL; Fiscal Year: 1990
    ..In addition, neoplasia associated with simian herpesvirus saimiri and Marek's disease virus serve as model systems for studying the underlying basis of herpesvirus oncogenicity...
  12. ROLE OF VIL-6 IN PRIMARY EFFUSION LYMPHOMAS
    John Nicholas; Fiscal Year: 2004
    ..and that of the herpesviruses for which sequence data are available it is most closely related to herpesvirus saimiri (HVS)...
  13. KAPOSIS SARCOMA ASSOCIATED VIRUS IN AIDS/LYMPHOMAS
    Ethel Cesarman; Fiscal Year: 1999
    ..cloned and sequenced thus far have shown homology and collinearity with Epstein-Barr virus (EBV) and herpesvirus saimiri (HVS), we will take advantage of methodologies previously established for the study of the role of these viruses ..
  14. HIV1 INHIBITORY PROTEINS FROM TRANSFORMED CD8+ CELLS
    Mary Klotman; Fiscal Year: 2002
    ..Herpesvirus saimiri (HVS)-transformed CD8+ cells have proven to provide a continuous source of supernatant with potent HIV-1 ..
  15. Toward a new world monkey model of HIV-1 infection
    Michael Farzan; Fiscal Year: 2007
    ..owl monkey (Aotus trivirgatus) and the common marmoset (Callithrixjacchus), but not those of the squirrel monkey (Saimiri sciureus), can be readily overcome...
  16. MOLECULAR BASIS FOR HERPESVIRUS SAIMIRI ONCOGENICITY
    Jae U Jung; Fiscal Year: 2013
    ....
  17. SUPPRESSION OF HIV REPLICATION BY CD8+ CELLS
    Jay Levy; Fiscal Year: 1999
    ..Toward recovery and identification of CAF, we have established Herpes virus saimiri-transformed CD8+ cells producing this factor as well as T cell hybridoma lines releasing CAF...
  18. THYMOMA TYROSINE PROTEIN KINASE
    BARTHOLOMEW SEFTON; Fiscal Year: 2004
    ..In addition, Lck is the target of the product of the Tip oncogene of herpesvirus saimiri. This simian herpesvirus induces an aggressive T cell leukemia...
  19. Immune Evasion and Protein Trafficking Piracy by KSHV
    Robert Means; Fiscal Year: 2004
    ..based on genome co-linearity and homology with several other members of this sub-group including Herpesvirus saimiri and Rhesus rhadinovirus...
  20. TUMOR ASSOCIATED HERPESVIRUSES CONFERENCE
    Nancy Raab Traub; Fiscal Year: 2000
    ..b>saimiri and primate EBV's. The biennial EBV symposia provides the only regular forum for EBV research...
  21. MECHANISM OF GAMMA-HERPESVIRUS DAF/MCP HOMOLOG
    Herbert Virgin; Fiscal Year: 2004
    ..is conserved in both position and structure between Kaposi's sarcoma herpesvirus (KSHV, HHV8), herpesvirus saimiri, and gammaHV68, strongly arguing for an important function...
  22. PERIODONTAL DISEASE RESEARCH CENTER
    William Clark; Fiscal Year: 1992
    ..The objective of the squirrel monkey (Saimiri sciureus) study is to develop an in vivo model for colonization with suspected periodontal pathogens (e.g., B...
  23. A Rapid Lateral Flow Test for TB in Nonhuman Primates
    Carol Nacy; Fiscal Year: 2004
    ..tb) or M. bovis in macaque and saimiri species of primates, and that the test does not give false positive results due to infections/exposures to M...
  24. MURINE GAMMAHERPESVIRUS 68 GENE EXPRESSION AND FUNCTION
    SAMUEL DUBOISE; Fiscal Year: 2001
    ..This gene cluster is present in related rhadinoviruses including KSHV and herpesvirus saimiri (HSV), but the presence of a Bcl-2 homolog within this cluster is unique to MHV-68...
  25. Herpesvirus saimiri TIP
    Jae Jung; Fiscal Year: 2009
    ..is directed toward investigating the molecular mechanism of signal transduction induced by the herpesvirus saimiri (HVS) tyrosine kinase interacting protein (Tip)...
  26. Early Chronic Stress and Prefrontal Development
    David Lyons; Fiscal Year: 2005
    ..abstract_text> ..
  27. IDENTIFICATION OF NOVEL HIV1 HOST RESISTANCE FACTORS
    Kunal Saha; Fiscal Year: 2002
    Herpesvirus saimiri (HVS) has been used in recent years as a tool in the study of human T cells...
  28. EXTRAMURAL RESEARCH FACILITIES CONSTRUCTION
    Christian Abee; Fiscal Year: 2004
    ..needed to help meet a critical need for housing and research space for a national resource of squirrel monkeys (Saimiri spp.) and owl monkeys (Aotus spp.)...
  29. A novel immune evasion strategy of KSHV K3 and K5
    Jae Jung; Fiscal Year: 2005
    ..test whether K3 and K5 are capable of contributing to the establishment of persistent infection of herpesvirus saimiri (HVS) in the natural host, squirrel monkeys, and to the induction of lymphoma by HVS in the non-natural hosts, ..
  30. CD8+ CELL NONCYTOLYTIC INHIBITION OF HIV-1
    Georgia Tomaras; Fiscal Year: 2000
    ..He also will characterize the factors from the Herpes-virus saimiri line that he has developed and examine the chemokines recently reported to be involved...
  31. STUDY OF KSHV REACTIVATION AND PATHOGENESIS
    Jae Jung; Fiscal Year: 2003
    ..LMP2A function in EBV LMP2A- lymphoblastoid cell lines (LCLs) and for the Tip function in context of herpesvirus saimiri. The proposed studies will increase our understanding of molecular mechanism of the KSHV latency and pathogenesis...
  32. Primate Model of the Transition to Cocaine Addiction
    JAMES ROWLETT; Fiscal Year: 2005
    ..The results will provide needed information for developing a nonhuman primate model that can serve as a quantitative platform for future research on neuroadaptations underlying the transition to persistent cocaine self-administration. ..
  33. Maternal Availability and Postnatal Brain Development
    Karen Parker; Fiscal Year: 2005
    ..This animal model provides valuable insights on a basic process in human development, insofar as early emotional challenges foster adaptations useful later in life. ..
  34. Nonhuman Primate Model of Benzodiazepine Relapse
    JAMES ROWLETT; Fiscal Year: 2002
    ....
  35. Optical Imaging of Mechanical Nociception in SI Cortex
    Li Min Chen; Fiscal Year: 2006
    ..This study will provide insights into how sensory aspects of nociceptive information are encoded in each area of SI. [unreadable] [unreadable]..
  36. Methylphenidate & gene expression in the rat brain.
    JOAN BAIZER; Fiscal Year: 2004
    ..abstract_text> ..
  37. AN ANIMAL MODEL OF GLUCOCORTICOID RESISTANCE
    Jonathan Scammell; Fiscal Year: 2007
    ..In summary, these studies will provide important insight into the physiological role of FKBP51 while at the same time adding substantial value to the Squirrel Monkey Resource at the University of South Alabama. ..
  38. STIMULUS-SPECIFIC SI CORTICOCORTICAL INTERACTIONS
    Barry Whitsel; Fiscal Year: 2007
    ..abstract_text> ..
  39. VESTIBULAR INFLUENCES ON SPATIAL ORIENTATION
    Richard Lewis; Fiscal Year: 2008
    ..abstract_text> ..
  40. International Symposium on Chronic Recovery from Stroke
    Randolph Nudo; Fiscal Year: 2002
    ....
  41. Factors Influencing Recovery From Spinal Cord Injury: The Signifiance of Spared S
    Hui Xin Qi; Fiscal Year: 2008
    ..Positive results will indicate the need for treatments that encourage the regeneration of even a few cut afferents, and promote the effectiveness of those that are preserved. [unreadable] [unreadable] [unreadable] [unreadable]..
  42. Corticospinal development after cortical inactivation
    KATHLEEN FRIEL; Fiscal Year: 2005
    ....
  43. Effects of Chronic THC in Adolescence
    Peter J Winsauer; Fiscal Year: 2010
    ..Together, data from these experiments will demonstrate how drug abuse and hormonal status during adolescence may permanently alter brain function and the liability of subsequent abuse of A9-THC. ..
  44. Neural mechanisms of 3-D linear vestibuloocular reflex
    Chiju Chen Huang; Fiscal Year: 2009
    ..abstract_text> ..
  45. NEURAL BASES OF MOTOR DYSFUNCTION AND REHABILITATION
    Randolph Nudo; Fiscal Year: 2004
    ....
  46. GENE EXPRESSION AND METHAMPHETAMINE NEUROTOXICITY
    George Ricaurte; Fiscal Year: 2002
    ..abstract_text> ..
  47. Cortical Stimulation to Enhance Recovery after Stroke
    Randolph Nudo; Fiscal Year: 2008
    ..It is expected that this program will serve as a model for the introduction of new therapeutic approaches to brain repair that are based on underlying neuroscientific principles. ..
  48. Physiology of vestibulo-thalamic pathways
    Robert McCrea; Fiscal Year: 2005
    ..abstract_text> ..
  49. Behavior in Mouse Tryptophan Hydroxylase Mutants
    Paresh Patel; Fiscal Year: 2007
    ..The candidate's long-term career plan is academic research integrating human clinical, genetic and animal model information for major mood disorders [unreadable] [unreadable]..
  50. REORGANIZATION OF MOTOR CORTEX FOLLOWING BRAIN INJURY
    Randolph Nudo; Fiscal Year: 2006
    ..It is hoped that eventually, therapeutic techniques for improving recovery of function after stroke will be based on the rules underlying plastic mechanisms in the central nervous system. ..
  51. PHYSIOLOGY OF OCULOMOTOR PREMOTOR PATHWAYS
    Robert McCrea; Fiscal Year: 2007
    ..The results should increase our understanding of the central mechanisms that allow clear vision of objects in a 3D environment during passive and active head movements. ..
  52. Do Housing Conditions Influence Learning & Retention of a Working Memory Task?
    JAMES CHURCHILL; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  53. Methamphetamine Neurotoxicity in Nonhuman Primates
    George Ricaurte; Fiscal Year: 2006
    ....
  54. MDMA Neurotoxicity in Humans: Occurence & Consequences
    George Ricaurte; Fiscal Year: 2006
    ....
  55. MDMA Neurotoxicity in Nonhuman Primates
    George Ricaurte; Fiscal Year: 2005
    ..abstract_text> ..
  56. CRYSTALLOGRAPHIC STUDIES OF VIRAL CYCLINS AND CDK6
    Ursula Schulze Gahmen; Fiscal Year: 2002
    ..V-cyclin from herpesvirus saimiri (HVS) and k- cyclin from Kaposi's sarcoma associated herpesvirus (KSHV) show 24 percent and 31 percent identity ..
  57. SAFETY ASSESSMENT OF FENFLURAMINE/PHENTERMINE
    George Ricaurte; Fiscal Year: 2001
    ....
  58. ADHD Treatment & Amphetamine Neurotoxicity
    George Ricaurte; Fiscal Year: 2007
    ....
  59. Cocaine Addiction:Medication Strategies and Evalution
    Jack Bergman; Fiscal Year: 2006
    ..abstract_text> ..
  60. Maternal Separation: Rat Model of Opioid Vulnerability
    STEPHEN HOLTZMAN; Fiscal Year: 2006
    ..abstract_text> ..