potoroidae

Summary

Summary: A family of rat kangaroos found in and around Australia. Genera include Potorous and Bettongia.

Top Publications

  1. doi Morphological and molecular characterization of Trypanosoma copemani n. sp. (Trypanosomatidae) isolated from Gilbert's potoroo ( Potorous gilbertii) and quokka ( Setonix brachyurus)
    J M Austen
    School of Veterinary and Biomedical Sciences, Division of Health Sciences, Murdoch University, South Street, Murdoch, Western Australia, 6150
    Parasitology 136:783-92. 2009
  2. doi Trypanosomes in a declining species of threatened Australian marsupial, the brush-tailed bettong Bettongia penicillata (Marsupialia: Potoroidae)
    A Smith
    WHO Collaborating Centre for the Molecular Epidemiology of Parasitic Infections, State Agricultural Biotechnology Centre, School of Veterinary and Biomedical Sciences, Murdoch University, Western Australia 6150, Australia
    Parasitology 135:1329-35. 2008
  3. pmc GPI-anchored receptor clusters transiently recruit Lyn and G alpha for temporary cluster immobilization and Lyn activation: single-molecule tracking study 1
    Kenichi G N Suzuki
    Membrane Mechanisms Project, International Cooperative Research Project, Japan Science and Technology Agency, The Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan
    J Cell Biol 177:717-30. 2007
  4. ncbi Signal analysis of total internal reflection fluorescent speckle microscopy (TIR-FSM) and wide-field epi-fluorescence FSM of the actin cytoskeleton and focal adhesions in living cells
    M C Adams
    Department of Cell Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    J Microsc 216:138-52. 2004
  5. ncbi Chromosomes can congress to the metaphase plate before biorientation
    Tarun M Kapoor
    Laboratory of Chemistry and Cell Biology, Rockefeller University, New York, NY 10021, USA
    Science 311:388-91. 2006
  6. ncbi Defining the regulatory elements in the proximal promoter of DeltaNp63 in keratinocytes: Potential roles for Sp1/Sp3, NF-Y, and p63
    Rose Anne Romano
    Department of Biochemistry, State University of New York at Buffalo, Buffalo, New York, USA
    J Invest Dermatol 126:1469-79. 2006
  7. ncbi Actin and alpha-actinin dynamics in the adhesion and motility of EPEC and EHEC on host cells
    Nathan C Shaner
    Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6058, USA
    Cell Motil Cytoskeleton 60:104-20. 2005
  8. pmc Taxol-stabilized microtubules can position the cytokinetic furrow in mammalian cells
    Katie B Shannon
    Department of Biology, University of North Carolina, Chapel Hill, NC 27599 3280, USA
    Mol Biol Cell 16:4423-36. 2005
  9. ncbi Microtubules tethered at epithelial cell junctions by dynein facilitate efficient junction assembly
    Lee A Ligon
    Department of Biology and the Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180, USA
    Traffic 8:808-19. 2007
  10. ncbi Calmodulin bound to stress fibers but not microtubules involves regulation of cell morphology and motility
    Jun Yuan
    Jiangsu Key Laboratory for Molecular and Medical Biotechnology, Nanjing Normal University, 1 Wen Yuan Road, Nanjing, China
    Int J Biochem Cell Biol 40:284-93. 2008

Research Grants

  1. KINESIN LIKE MOTORS IN MITOTIC MOVEMENTS
    J McIntosh; Fiscal Year: 2004
  2. An Elastic Model of Spirochete Morphology and Motility
    Charles Wolgemuth; Fiscal Year: 2007
  3. Kinetochore-Microtubule Interactions in Fission Yeast
    J McIntosh; Fiscal Year: 2007
  4. Kinetochore-Microtubule Interactions
    JOHN RICHARD MCINTOSH; Fiscal Year: 2010
  5. Kinetochore-Microtubule Interactions
    J McIntosh; Fiscal Year: 2009
  6. KINESIN LIKE MOTORS IN MITOTIC MOVEMENTS
    J McIntosh; Fiscal Year: 2000
  7. KINESIN-LIKE MOTORS IN MITOTIC MOVEMENTS
    J McIntosh; Fiscal Year: 1993
  8. MICROTUBULE DYNAMICS IN VIVO
    J McIntosh; Fiscal Year: 1992
  9. Biophysics of the morphology and motility of Borrelia burgdorferi in diverse envi
    Charles W Wolgemuth; Fiscal Year: 2010

Scientific Experts

Detail Information

Publications85

  1. doi Morphological and molecular characterization of Trypanosoma copemani n. sp. (Trypanosomatidae) isolated from Gilbert's potoroo ( Potorous gilbertii) and quokka ( Setonix brachyurus)
    J M Austen
    School of Veterinary and Biomedical Sciences, Division of Health Sciences, Murdoch University, South Street, Murdoch, Western Australia, 6150
    Parasitology 136:783-92. 2009
    ..The new species is proposed to be named Trypanosoma copemani n. sp...
  2. doi Trypanosomes in a declining species of threatened Australian marsupial, the brush-tailed bettong Bettongia penicillata (Marsupialia: Potoroidae)
    A Smith
    WHO Collaborating Centre for the Molecular Epidemiology of Parasitic Infections, State Agricultural Biotechnology Centre, School of Veterinary and Biomedical Sciences, Murdoch University, Western Australia 6150, Australia
    Parasitology 135:1329-35. 2008
    ..Although it appears unlikely that the parasite is solely responsible for the decline in woylie population size, it may (singularly or in conjunction with other infectious agents) predispose woylies to increased mortality...
  3. pmc GPI-anchored receptor clusters transiently recruit Lyn and G alpha for temporary cluster immobilization and Lyn activation: single-molecule tracking study 1
    Kenichi G N Suzuki
    Membrane Mechanisms Project, International Cooperative Research Project, Japan Science and Technology Agency, The Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan
    J Cell Biol 177:717-30. 2007
    ....
  4. ncbi Signal analysis of total internal reflection fluorescent speckle microscopy (TIR-FSM) and wide-field epi-fluorescence FSM of the actin cytoskeleton and focal adhesions in living cells
    M C Adams
    Department of Cell Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    J Microsc 216:138-52. 2004
    ..When used in time-lapse mode, TIR-FSM of actin and GFP-conjugated focal adhesion proteins will allow quantification of molecular dynamics within interesting macromolecular assemblies at the ventral surface of living cells...
  5. ncbi Chromosomes can congress to the metaphase plate before biorientation
    Tarun M Kapoor
    Laboratory of Chemistry and Cell Biology, Rockefeller University, New York, NY 10021, USA
    Science 311:388-91. 2006
    ..This congression mechanism depended on the kinetochore-associated, plus end-directed microtubule motor CENP-E (kinesin-7)...
  6. ncbi Defining the regulatory elements in the proximal promoter of DeltaNp63 in keratinocytes: Potential roles for Sp1/Sp3, NF-Y, and p63
    Rose Anne Romano
    Department of Biochemistry, State University of New York at Buffalo, Buffalo, New York, USA
    J Invest Dermatol 126:1469-79. 2006
    ..These studies support the notion that unique and distinct pathways control the expression of individual p53 family members and their various isoforms...
  7. ncbi Actin and alpha-actinin dynamics in the adhesion and motility of EPEC and EHEC on host cells
    Nathan C Shaner
    Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6058, USA
    Cell Motil Cytoskeleton 60:104-20. 2005
    ..A simple physical model was developed to describe elongation and translocation of EPEC/EHEC pedestals in terms of actin polymerization and depolymerization dynamics...
  8. pmc Taxol-stabilized microtubules can position the cytokinetic furrow in mammalian cells
    Katie B Shannon
    Department of Biology, University of North Carolina, Chapel Hill, NC 27599 3280, USA
    Mol Biol Cell 16:4423-36. 2005
    ..We discuss our findings relative to models for cleavage stimulation...
  9. ncbi Microtubules tethered at epithelial cell junctions by dynein facilitate efficient junction assembly
    Lee A Ligon
    Department of Biology and the Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180, USA
    Traffic 8:808-19. 2007
    ....
  10. ncbi Calmodulin bound to stress fibers but not microtubules involves regulation of cell morphology and motility
    Jun Yuan
    Jiangsu Key Laboratory for Molecular and Medical Biotechnology, Nanjing Normal University, 1 Wen Yuan Road, Nanjing, China
    Int J Biochem Cell Biol 40:284-93. 2008
    ..The data we have got from living cells suggested that CaM affect cell morphology and motility through binding to stress fibers and regulate f-actin polymerization...
  11. ncbi Topography, structure and function of the patella and the patelloid in marsupials
    S Reese
    Institute of Veterinary Anatomy I, University of Munich, Germany
    Anat Histol Embryol 30:289-94. 2001
    ..Pseudocheriidae, and Potoroidae; (2) Burramyidae; (3) Phascolarctidae, Vombatidae, and Dendrolagus; and (4) Superfamily Macropodoidea (except ..
  12. doi A phylogeny of Diprotodontia (Marsupialia) based on sequences for five nuclear genes
    Robert W Meredith
    Department of Biology, University of California, 900 University Avenue, Riverside, CA 92521, USA
    Mol Phylogenet Evol 51:554-71. 2009
    ..Phalangerida is composed of the kangaroos (Macropodidae, Potoroidae, and Hypsiprymnodontidae) and possums (Phalangeridae, Burramyidae, Petauridae, Pseudocheiridae, Tarsipedidae, ..
  13. pmc Dynamic bonds and polar ejection force distribution explain kinetochore oscillations in PtK1 cells
    Gul Civelekoglu-Scholey
    Department of Molecular and Cellular Biology, University of California, Davis, CA 95616, USA
    J Cell Biol 201:577-93. 2013
    ....
  14. ncbi Phylogenetic analysis of diprotodontian marsupials based on complete mitochondrial genomes
    Maruo Munemasa
    Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Kanagawa, Japan
    Genes Genet Syst 81:181-91. 2006
    ..which contains Phascolarctidae (koala) and Vombatidae (wombat), and Phalangerida, which contains Macropodidae, Potoroidae, Phalangeridae, Petauridae, Pseudocheiridae, Acrobatidae, Tarsipedidae and Burramyidae...
  15. pmc p31(comet) acts to ensure timely spindle checkpoint silencing subsequent to kinetochore attachment
    Robert S Hagan
    Center for Cell Decision Processes, Harvard Medical School, Boston, MA 02115, USA
    Mol Biol Cell 22:4236-46. 2011
    ..Thus p31(comet) is required for timely mitotic exit. We propose that p31(comet) is an essential component of the machinery that silences the checkpoint during each cell cycle...
  16. pmc Deformations within moving kinetochores reveal different sites of active and passive force generation
    Sophie Dumont
    Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA
    Science 337:355-8. 2012
    ..Together, these interfaces allow persistent attachment with intermittent active force generation...
  17. doi Novel insights into the phylogenetic relationships of the endangered marsupial genus Potorous
    Greta J Frankham
    Department of Zoology, University of Melbourne, Melbourne, Victoria 3010, Australia
    Mol Phylogenet Evol 64:592-602. 2012
    ..Molecular dating estimated that divergences within Potorous occurred in the late Miocene through to the early Pliocene...
  18. doi Identification of novel Babesia and Theileria genotypes in the endangered marsupials, the woylie (Bettongia penicillata ogilbyi) and boodie (Bettongia lesueur)
    Andrea Paparini
    Division of Health Sciences, Murdoch University, Murdoch, Western Australia 6150, Australia
    Exp Parasitol 131:25-30. 2012
    ..from the long-nosed potoroo (Potorous tridactylus)...
  19. pmc Dynamic recruitment of phospholipase C gamma at transiently immobilized GPI-anchored receptor clusters induces IP3-Ca2+ signaling: single-molecule tracking study 2
    Kenichi G N Suzuki
    Membrane Mechanisms Project, International Cooperative Research Project, Japan Science and Technology Agency, The Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan
    J Cell Biol 177:731-42. 2007
    ....
  20. pmc Native 3D intermediates of membrane fusion in herpes simplex virus 1 entry
    Ulrike E Maurer
    Department of Molecular Structural Biology, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany
    Proc Natl Acad Sci U S A 105:10559-64. 2008
    ..Moreover, our data suggest that there are two functional "poles" of the asymmetric herpesvirion: one related to cell entry, and the other formed during virus assembly...
  21. ncbi Magnetic nanoparticle-based mass spectrometry for the detection of biomolecules in cultured cells
    Shinji Moritake
    Department of Physics, Graduate School of Engineering, Yokohama National University, 79 5 Tokiwadai, Hodogaya ku, Yokohama 240 8501, Japan
    J Nanosci Nanotechnol 9:169-76. 2009
    ..Our new nanoparticle-assisted laser desorption/ionization mass spectrometry technique is a quick and convenient way to profile biomolecules in cultured cells...
  22. pmc Fibrils connect microtubule tips with kinetochores: a mechanism to couple tubulin dynamics to chromosome motion
    J Richard McIntosh
    Department of M C D Biology, University of Colorado, Boulder, CO 80309 0347, USA
    Cell 135:322-33. 2008
    ..These analyses define a ring-independent mechanism for harnessing microtubule dynamics directly to chromosome movement...
  23. ncbi Cryptococcosis in Gilbert's and long-nosed potoroo
    R J Vaughan
    Veterinary Department, Perth Zoo, 20 Labouchere Road, South Perth, Western Australia 6151, Australia
    J Zoo Wildl Med 38:567-73. 2007
    ..Pulmonary infection was also observed in the long-nosed potoroo. Specific treatment with antifungal agents was unsuccessful in the long-nosed potoroo...
  24. doi Tubulohelical membrane arrays: novel association of helical structures with intracellular membranes
    Siegfried Reipert
    Department of Molecular Cell Biology, Max F Perutz Laboratories, Dr Bohr Gasse 9, University of Vienna, A 1030 Vienna, Austria
    Cell Biol Int 33:217-23. 2009
    ..This should make TUHMAs more easily accessible for future studies on their structure and function...
  25. pmc Unique features of spermiogenesis in the Musky Rat-kangaroo: reflection of a basal lineage or a distinct fertilization process?
    Shan Lloyd
    School of Veterinary Science, University of Queensland, St Lucia 4072, QLD Australia
    J Anat 212:257-74. 2008
    ....
  26. pmc Stimulated emission depletion (STED) nanoscopy of a fluorescent protein-labeled organelle inside a living cell
    Birka Hein
    Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, 37070 Gottingen, Germany
    Proc Natl Acad Sci U S A 105:14271-6. 2008
    ..Time-lapse STED recordings document morphological changes of the ER over time. Thus, nanoscale 3D imaging of organelles in the interior of living cells greatly expands the scope of light microscopy in cell biology...
  27. pmc 4Pi microscopy of the nuclear pore complex
    Jana Hüve
    Institute of Medical Physics and Biophysics, and Center for Nanotechnology CeNTech, University of Munster, Munster, Germany
    Biophys J 95:877-85. 2008
    ..We conclude that super-resolution fluorescence microscopy is a powerful method for analyzing single protein complexes and the cellular nanomachinery in general...
  28. doi Synaptopodin maintains the neural activity-dependent enlargement of dendritic spines in hippocampal neurons
    Reiko Okubo-Suzuki
    Mitsubishi Kagaku Institute of Life Sciences, MITILS, 11 Minamiooya, Machida, Tokyo 194 8511, Japan
    Mol Cell Neurosci 38:266-76. 2008
    ..These results suggest that SYNPO stabilized activity-dependent increases in spine volume and imply that late-phase changes in spine morphology involve SYNPO...
  29. pmc Comparative study on the effect of human BST-2/Tetherin on HIV-1 release in cells of various species
    Kei Sato
    Laboratory of Viral Pathogenesis, Institute for Virus Research, Kyoto University, Kyoto, Kyoto 606 8507, Japan
    Retrovirology 6:53. 2009
    ..The cell type-specific effect of hBST-2 may be critical to elucidate the mechanism of BST-2-dependent suppression of virus release...
  30. doi Theileria gilberti n. sp. (Apicomplexa: Theileriidae) in the Gilbert's potoroo (Potorous gilbertii)
    Jeremy Y Lee
    Murdoch University, Western Australia, Australia
    J Eukaryot Microbiol 56:290-5. 2009
    ..Based on biological and molecular data, it is proposed that the parasite from Gilbert's potoroo be given the name Theileria gilberti n. sp...
  31. doi Monitoring reproduction in the critically endangered marsupial, Gilbert's potoroo (Potorous gilbertii): preliminary analysis of faecal oestradiol-17beta, cortisol and progestagens
    Ernie Stead-Richardson
    School of Animal Biology, The University of Western Australia, Perth, WA 6009, Australia
    Gen Comp Endocrinol 165:155-62. 2010
    ..Faecal cortisol levels in captive females were significantly lower than those in wild-caught individuals and thus there is no indication that elevated cortisol levels per se inhibited reproduction in captive females...
  32. pmc Pak1 regulates focal adhesion strength, myosin IIA distribution, and actin dynamics to optimize cell migration
    Violaine D Delorme-Walker
    Department of Immunology and Microbial Sciences, The Scripps Research Institute, La Jolla, CA 92037, USA
    J Cell Biol 193:1289-303. 2011
    ..These findings establish Paks as critical molecules coordinating cytoskeletal systems for efficient cell migration...
  33. doi PERMANENT GENETIC RESOURCES: Cross-family amplification: microsatellites isolated from Macropodidae are polymorphic in Potoroidae
    F R Donaldson
    School of Animal Biology, The University of Western Australia, Crawley 6009, WA, Australia
    Mol Ecol Resour 8:452-4. 2008
    The superfamily Macropodoidea consists of two families - the Macropodidae and Potoroidae. Cross-species amplification and polymorphism of microsatellite loci is widely recognized within the macropodid family; however, the success of ..
  34. doi Cellular localisation of antitumoral 6-alkyl thymoquinones revealed by an alkyne-azide click reaction and the streptavidin-biotin system
    Katharina Effenberger-Neidnicht
    Organic Chemistry Laboratory, University Bayreuth, Bayreuth, Germany
    Chembiochem 12:1237-41. 2011
    ..In conclusion, for small drug-like molecules, visualisation by alkyne-azide cycloaddition seems to be superior to conventional visualisation by the biotin-streptavidin system...
  35. ncbi Hematological and serum biochemical reference values and cohort analysis in the Gilbert's potoroo (Potorous gilbertii)
    Rebecca J Vaughan
    School of Veterinary and Health Sciences, Murdoch University, South Street, Murdoch, Western Australia 6150
    J Zoo Wildl Med 40:276-88. 2009
    ..These reference ranges and findings will assist in the ongoing health management of this critically endangered species. hematology, biochemistry, marsupial, Gilbert's potoroo, Potorous gilbertii...
  36. doi 3-D reconstruction of microtubules from multi-angle total internal reflection fluorescence microscopy using Bayesian framework
    Qian Yang
    Department of Electrical Engineering, Yale University, New Haven, CT 06511, USA
    IEEE Trans Image Process 20:2248-59. 2011
    ..The presented method has the potential to provide a reliable tool for 3-D reconstruction and tracking of microtubules...
  37. pmc Structure and expression of two nuclear receptor genes in marsupials: insights into the evolution of the antisense overlap between the α-thyroid hormone receptor and Rev-erbα
    Brandon C Rindfleisch
    Department of Biological Sciences, Marquette University, Milwaukee, WI, USA
    BMC Mol Biol 11:97. 2010
    ....
  38. pmc Multicolor fluorescence nanoscopy in fixed and living cells by exciting conventional fluorophores with a single wavelength
    Ilaria Testa
    Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Gottingen, Germany
    Biophys J 99:2686-94. 2010
    ..The method can be expanded to even more colors by choosing optimized dichroic mirrors and selecting marker molecules with negligible inhomogeneous emission broadening...
  39. pmc Chromosome tips damaged in anaphase inhibit cytokinesis
    Norman M Baker
    Department of Electrical and Computer Engineering, University of California San Diego, La Jolla, California, United States of America
    PLoS ONE 5:e12398. 2010
    ..When multiple chromosome tips were irradiated in the same cell, the cytokinesis defects increased, suggesting a potential dose-dependent mechanism. These results suggest a mechanism in which dysfunctional telomeres inhibit mitotic exit...
  40. pmc Coupling between clathrin-dependent endocytic budding and F-BAR-dependent tubulation in a cell-free system
    Min Wu
    Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06520, USA
    Nat Cell Biol 12:902-8. 2010
    ..They also show that clathrin spatially directs plasma membrane invaginations that lead to the generation of endocytic vesicles larger than those enclosed by the coat...
  41. pmc Chlamydia pneumoniae is genetically diverse in animals and appears to have crossed the host barrier to humans on (at least) two occasions
    Candice M Mitchell
    Institute of Health and Biomedical Innovation, School of Life Sciences, Queensland University of Technology, Kelvin Grove, Queensland, Australia
    PLoS Pathog 6:e1000903. 2010
    ..We identified a separate human lineage present in two Australian Indigenous isolates (independent geographical locations). This lineage is distinct and is present in Australian amphibians as well as a range of Australian marsupials...
  42. pmc Fast molecular tracking maps nanoscale dynamics of plasma membrane lipids
    Steffen J Sahl
    Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Gottingen, Germany
    Proc Natl Acad Sci U S A 107:6829-34. 2010
    ..Our experimental approach demonstrates that fast molecular movements can be tracked with minimal invasion, which can reveal new important details of cellular nano-organization...
  43. pmc The first complete papillomavirus genome characterized from a marsupial host: a novel isolate from Bettongia penicillata
    Mark D Bennett
    School of Veterinary and Biomedical Sciences, Murdoch University, South Street, Murdoch, Western Australia 6150, Australia
    J Virol 84:5448-53. 2010
    ..It appears that the BPCVs arose by recombination between an ancient PV and an ancient polyomavirus more than 10 million years ago...
  44. doi Both actin and myosin inhibitors affect spindle architecture in PtK1 cells: does an actomyosin system contribute to mitotic spindle forces by regulating attachment and movements of chromosomes in mammalian cells?
    Judith A Snyder
    Department of Biological Sciences, University of Denver, Denver, CO 80208, USA
    Protoplasma 240:57-68. 2010
    ..Evidence is presented to suggest that an actomyosin system may help to regulate the initial and continued attachment of chromosomes to the mammalian spindle and could also influence spindle checkpoint(s)...
  45. doi Polarization sensitive, three-dimensional, single-molecule imaging of cells with a double-helix system
    Sri Rama Prasanna Pavani
    Department of Electrical and Computer Engineering, University of Colorado, Boulder, CO 80309, USA
    Opt Express 17:19644-55. 2009
    ..Further, we show that the 3D information from the two channels can be optimally combined to yield up to 30% improvement in localization precision relative to a single polarization channel system...
  46. doi Aneuploidy in mitosis of PtK1 cells is generated by random loss and nondisjunction of individual chromosomes
    Liliana Torosantucci
    IBPM Institute of Molecular Biology and Pathology, CNR National Research Council, University La Sapienza, Via degli Apuli 4, 00185 Rome, Italy
    J Cell Sci 122:3455-61. 2009
    ..Our findings imply random missegregation of chromosomes as the initial event in the generation of aneuploidy in mammalian somatic cells...
  47. pmc The Potorous CPD photolyase rescues a cryptochrome-deficient mammalian circadian clock
    Inês Chaves
    Department of Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands
    PLoS ONE 6:e23447. 2011
    ....
  48. ncbi Relationships between plasma composition and parotid salivary composition and secretion rates in the potoroine marsupials, Aepyprymnus rufescens and Potorous tridactylus
    A M Beal
    School of Biological Science, University of New South Wales, Kensington, Australia
    J Comp Physiol B 162:637-45. 1992
    ..Buffer anion concentrations and secretion rates were similar to koalas and low relative to kangaroos, indicating that these potoroines do not rely on foregut fermentation...
  49. ncbi Myosin isoforms and fibre types in jaw-closing muscles of Australian marsupials
    Joseph F Y Hoh
    Discipline of Physiology and Institute for Biomedical Research, School of Medical Sciences, Faculty of Medicine, Bldg F13, The University of Sydney, Sydney, NSW 2006, Australia
    J Comp Physiol B 176:685-95. 2006
    ..The fact that the bettong (Family: Potoroidae), which belong to the same marsupial superfamily (Macropodoidea) as kangaroos and wallabies (Family: ..
  50. ncbi Colocalization studies of Arp1 and p150Glued to spindle microtubules during mitosis: the effect of cytochalasin on the organization of microtubules and motor proteins in PtK1 cells
    Rollin W Robinson
    Department of Biological Sciences, University of Denver, 2190 E Iliff Avenue, Denver, CO 80208, USA
    Cell Biol Int 30:631-9. 2006
    ..Cytochalasin J has less of an effect on the colocalization of p150(Glued) with spindle MTs, suggesting that Arp1 may have a cytochalasin J sensitive site...
  51. pmc In vivo quantitative studies of dynamic intracellular processes using fluorescence correlation spectroscopy
    Zifu Wang
    Developmental Biology Center, Beckman Laser Institute, and Department of Biomedical Engineering, University of California, Irvine, and Ludwig Institute for Cancer Research, La Jolla, California, USA
    Biophys J 91:343-51. 2006
    ..Photon counting histograms reveal that both complexes contain only a single molecule of Cdc20. The underlying mechanisms of the activities of APC/CCdc20 throughout the cell cycle are discussed in light of our experimental observations...
  52. ncbi Length control of primary cilia: analysis of monociliate and multiciliate PtK1 cells
    D N Wheatley
    Department of Cell Pathology, University of Aberdeen, UK
    Biol Cell 92:573-82. 2000
    ..Thus, length of primary cilia in PtK1 cell populations is considerably less stringently controlled than in PtK1 cells bearing 9 + 2 cilia, but those issuing from a single multiciliated cell tend to show better correspondence...
  53. ncbi Localization of chromosome regions in potoroo nuclei ( Potorous tridactylus Marsupialia: Potoroinae)
    W Rens
    Department of Clinical Veterinary Medicine, University of Cambridge, Cambridge CB3 OES, UK
    Chromosoma 112:66-76. 2003
    ..Its relationship with replication patterns in interphase nuclei and metaphase was studied. In addition it was observed that the nucleus was not a smooth entity but had projections occupied by specific chromosome regions...
  54. pmc Periodic patterns of actin turnover in lamellipodia and lamellae of migrating epithelial cells analyzed by quantitative Fluorescent Speckle Microscopy
    A Ponti
    Department of Cell Biology, The Scripps Research Institute, La Jolla, California, USA
    Biophys J 89:3456-69. 2005
    ..Several algorithmic advances in speckle image processing are described enabling the analysis of kinetic and kinematic activities of polymer networks at the level of single speckles...
  55. ncbi Fire, hypogeous fungi and mycophagous marsupials
    James M Trappe
    Mycol Res 109:516-8. 2005
  56. pmc Lamellipodial contractions during crawling and spreading
    Charles W Wolgemuth
    University of Connecticut Health Center, Department of Cell Biology, Farmington, Connecticut, USA
    Biophys J 89:1643-9. 2005
    ....
  57. pmc Bacterial shape and ActA distribution affect initiation of Listeria monocytogenes actin-based motility
    Susanne M Rafelski
    Department of Biochemistry, Stanford University Medical Center, Stanford, California 94305 5307, USA
    Biophys J 89:2146-58. 2005
    ..Over time, saltatory motility and sensitivity to the immediate environment decreased as bacterial movement became robust at a constant steady-state speed...
  58. ncbi Archazolids, new cytotoxic macrolactones from Archangium gephyra (Myxobacteria). Production, isolation, physico-chemical and biological properties
    Florenz Sasse
    GBF, German Research Centre for Biotechnology, Department Natural Product Biology, Mascheroder Weg 1, D 38124 Braunschweig, Germany
    J Antibiot (Tokyo) 56:520-5. 2003
    ..We therefore assume that archazolid is an inhibitor of the V-ATPase of higher cells...
  59. ncbi Molecular phylogenetic relationships of two extinct potoroid marsupials, Potorous platyops and Caloprymnus campestris (Potoroinae: Marsupialia)
    M Westerman
    Genetics Department, LaTrobe University, Bundoora, VIC 3086, Australia
    Mol Phylogenet Evol 31:476-85. 2004
    ..Within Potoroinae, C. campestris diverged from other taxa approximately 16 million years ago. P. platyops diverged from P. longipes+P. gilberti approximately 14-15 million years ago...
  60. ncbi A polarity dependent fluorescence "switch" in live cells
    Michael W Berns
    Department of Biomedical Engineering, Beckman Laser Institute, University of California, 1002 Health Sciences Rd East, Irvine, CA 92612, USA
    J Photochem Photobiol B 75:51-6. 2004
    ..A possible use as a bi-stable, on/off sensor is discussed...
  61. pmc Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint
    Daniela A Brito
    Department of Biomedical Sciences, School of Public Health, State University of New York, Albany, New York 12222, USA
    Curr Biol 16:1194-200. 2006
    ..Thus, vertebrate cells do not adapt to the SAC. Rather, our data suggest that in normal cells, the SAC cannot prevent a slow but continuous degradation of cyclin B that ultimately drives the cell out of mitosis...
  62. pmc Deciphering protein function during mitosis in PtK cells using RNAi
    Jane R Stout
    Department of Biochemistry and Molecular Biology, Indiana University Medical Sciences, Bloomington, Indiana 47405, USA
    BMC Cell Biol 7:26. 2006
    ..PtK cells, due to their flat morphology and their small number of large chromosomes, allow microscopic visualizations to be readily performed...
  63. ncbi Energy metabolism in potoroine marsupials
    I R Wallis
    Department of Biochemistry, Microbiology and Nutrition, University of New England, Armidale, NSW, Australia
    J Comp Physiol B 162:478-87. 1992
    ..The presence of pouch young did not alter the efficiency of utilisation of metabolisable energy. The daily energy requirement for maintenance was 0.83 MJ.day-1 or 0.36 MJ.kg-0.75.day-1...
  64. ncbi Mice expressing a mutant Krt75 (K6hf) allele develop hair and nail defects resembling pachyonychia congenita
    Jiang Chen
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, USA
    J Invest Dermatol 128:270-9. 2008
    ....
  65. ncbi Survival-related DNA repair phenomena in cultured rat-kangaroo cells
    C B Schroy
    Department of Biochemistry and Biophysics, Pennsylvania State University, University Park, PA 16802, USA
    Mutat Res 35:269-77. 1976
    ....
  66. ncbi Propagation and quantitation of animal herpesviruses in eight cell culture systems
    R B Peterson
    Department of Veterinary Diagnostic Investigation, College of Veterinary Medicine, University of Minnesota, St Paul 55108
    Comp Immunol Microbiol Infect Dis 11:93-8. 1988
    ..BT and OFL cells were also found to be highly sensitive to all viruses with the exception of CHV...
  67. pmc p63 induces key target genes required for epidermal morphogenesis
    Maranke I Koster
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 104:3255-60. 2007
    ..Our data provide insights into the role of DeltaNp63alpha in epidermal morphogenesis and homeostasis, and may contribute to our understanding of the pathogenic mechanisms underlying disorders caused by p63 mutations...
  68. ncbi Preventative antiinflammatory effect of potamogetonan, a pectin from the common pondweed Potamogeton natans L
    Sergey V Popov
    Institute of Physiology, Komi Science Centre, The Urals Branch of the Russian Academy of Sciences, 50, Pervomaiskaya str, 167982 Syktyvkar, Republic Komi, Russia
    Phytother Res 21:609-14. 2007
    ..Thus, a pectin named potamogetonan PN-300 was isolated from P. natans and was shown to possess a preventive antiinflammatory effect following oral administration...
  69. ncbi Differential transmission of actin motion within focal adhesions
    Ke Hu
    Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Science 315:111-5. 2007
    ....
  70. ncbi Mammalian cell nano structures visualized by cryo Hilbert differential contrast transmission electron microscopy
    Mitsutoshi Setou
    National Institute of Physiological Sciences, Nano Structural Physiology, 5 1 Higashiyama, Myodaiji cho, Okazaki, 444 8787, Japan
    Med Mol Morphol 39:176-80. 2006
    ..Thus, Hilbert differential contrast phase electron microscopy of vitrified cells is a nano-scale molecular imaging technique that opens up new vistas for exploring the supramolecular organization of the mammalian cell...
  71. pmc Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues
    Y Ando-Akatsuka
    Department of Cell Biology, Faculty of Medicine, Kyoto University, Japan
    J Cell Biol 133:43-7. 1996
    ..Implications of these data and novel experimental options in cell biological research are discussed...
  72. ncbi Effects of rhizopodin and latrunculin B on the morphology and on the actin cytoskeleton of mammalian cells
    T M Gronewold
    Department of Biology of Natural Products, Gesellschaft fur Biotechnologische Forschung, Mascheroder Weg 1, D 38124 Braunschweig, Germany
    Cell Tissue Res 295:121-9. 1999
    ..The microtubuli network adjusted itself to the new cell morphology, but was not directly impaired by the compound...
  73. ncbi Aurora kinase promotes turnover of kinetochore microtubules to reduce chromosome segregation errors
    Daniela Cimini
    Department of Biology, 607 Fordham Hall, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    Curr Biol 16:1711-8. 2006
    ....
  74. ncbi Phylogeography and population structure of an ecotonal marsupial, Bettongia tropica, determined using mtDNA and microsatellites
    L C Pope
    Department of Zoology and Entomology, University of Queensland, St Lucia, 4072 Queensland, Australia
    Mol Ecol 9:2041-53. 2000
    The northern bettong, Bettongia tropica, is an endangered species of Potoroidae with a restricted distribution in the wet tropics of north Queensland, Australia...
  75. ncbi An innovative fixative for cytoskeletal components allows high resolution in colocalization studies using immunofluorescence techniques
    Rollin W Robinson
    University of Denver, 2190 E Iliff Avenue, CO 80208, Denver, USA
    Histochem Cell Biol 122:1-5. 2004
    ..We present evidence that CytoSkelFix is a superior preservative and would be useful in fixation for all types of immunofluorescence colocalization studies where superior preservation is required...
  76. ncbi Incomplete sister chromatid separation of long chromosome arms
    W Rens
    Cambridge Resource Centre for Comparative Genomics, UK
    Chromosoma 115:481-90. 2006
    ..These findings suggest a limit in chromosome arm length for efficient chromosome transmission through mitosis...
  77. ncbi Localization of myosin II to chromosome arms and spindle fibers in PtK1 cells: a possible role for an actomyosin system in mitosis
    Rollin W Robinson
    Department of Biological Sciences, University of Denver, Denver, Colorado 80208, USA
    Protoplasma 225:113-22. 2005
    ..We conclude from this study that there is an actomyosin system present in the mitotic spindle and that myosin is attached to chromosome arms and may act as a thruster in moving chromosomes during the mitotic process...
  78. ncbi Efficient one-pot synthesis of biologically active polysubstituted aromatic amines
    Dirk Menche
    Helmholtz Zentrum für Infektionsforschung GmbH, Medizinische Chemie, Inhoffenstr 7, 38124 Braunschweig, Germany
    Bioorg Med Chem 15:7311-7. 2007
    ....
  79. ncbi Microtubule-tethering junctions are fine structural distinct entities that deserve attention
    Siegfried Reipert
    Department of Molecular Cell Biology, Max F Perutz Laboratories, University of Vienna, Dr Bohr Gasse 9, A 1030 Vienna, Austria
    Traffic 8:1706-7. 2007
    ..Here, we encourage systematic analysis of cortical microtubule capture by electron microscopy...
  80. ncbi Decreased polarity and increased random motility in PtK1 epithelial cells correlate with inhibition of endosomal recycling
    Natalie L Prigozhina
    The Burnham Institute, La Jolla, CA 92037, USA
    J Cell Sci 119:3571-82. 2006
    ..We have also tested the effects of other Rab proteins, implicated in endocytic recycling, and discovered a clear correlation between the degree of recycling inhibition and the increase in non-directional cell motility...
  81. ncbi The pathomechanism of filaminopathy: altered biochemical properties explain the cellular phenotype of a protein aggregation myopathy
    Thomas Lowe
    Department of Cell Biology, University of Potsdam, 14476 Potsdam Golm, Germany
    Hum Mol Genet 16:1351-8. 2007
    ..The mutant filamin does not associate with wild type filamin. These findings are of great importance to explain the pathomechanism of this disease...
  82. ncbi Linker region of nebulin family members plays an important role in targeting these molecules to cellular structures
    Zivile Panaviene
    Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA
    Cell Tissue Res 327:353-69. 2007
    ..We have found that the linker region of LASP-1 is indeed important for its cellular localization and that the shortened linker region of LIM-nebulette drives the association of nebulin modules to focal adhesions...
  83. ncbi Demography in relation to population density in two herbivorous marsupials: testing for source-sink dynamics versus independent regulation of population size
    Christopher N Johnson
    School of Tropical Biology, James Cook University, Townsville, Queensland, 4811, Australia
    Oecologia 143:70-6. 2005
    ..The results of our study argue against this interpretation...
  84. pmc Lysed cell models and isolated chromosomes for the study of kinetochore/centromere biochemistry in vitro
    John R Daum
    Program in Molecular, Cell and Developmental Biology, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA
    Methods 38:52-9. 2006
    ..Here we present approaches to the in vitro study of signaling pathways in mitotic cells, particularly those involved in protein phosphorylation changes at kinetochores that may control cell cycle progression in M phase...
  85. ncbi In vivo selective cytoskeleton dynamics quantification in interphase cells induced by pulsed ultraviolet laser nanosurgery
    Julien Colombelli
    Cell Biology and Biophysics Unit, European Molecular Biology Laboratory EMBL, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
    Traffic 6:1093-102. 2005
    ..We extend the application of the method by demonstrating induced dynamic behavior of actin-stress fibers after severing. This new method enables the quantitative investigation of cytoskeleton dynamics in a local confinement...

Research Grants32

  1. KINESIN LIKE MOTORS IN MITOTIC MOVEMENTS
    J McIntosh; Fiscal Year: 2004
    ..g., tension) modify the physiology of the kinetochore ..
  2. An Elastic Model of Spirochete Morphology and Motility
    Charles Wolgemuth; Fiscal Year: 2007
    ..This grant will also support the experimental measurement of the bending moduli of the cell wall and the periplasmic flagella. ..
  3. Kinetochore-Microtubule Interactions in Fission Yeast
    J McIntosh; Fiscal Year: 2007
    ..The results from our work will inform biomedical science about important drug targets for cancer chemotherapy and genes that are significant for minimizing the risk of aneuploidy in both mitosis and meiosis. ..
  4. Kinetochore-Microtubule Interactions
    JOHN RICHARD MCINTOSH; Fiscal Year: 2010
    ..We may also help to identify proteins that are ideally suited to serve as targets for the discovery of new drugs that block cell division, one of the strategies that is currently used by some of the effective cancer chemotherapeutics. ..
  5. Kinetochore-Microtubule Interactions
    J McIntosh; Fiscal Year: 2009
    ..We may also help to identify proteins that are ideally suited to serve as targets for the discovery of new drugs that block cell division, one of the strategies that is currently used by some of the effective cancer chemotherapeutics. ..
  6. KINESIN LIKE MOTORS IN MITOTIC MOVEMENTS
    J McIntosh; Fiscal Year: 2000
    ..Through this combination of studies we hope to identify the mitotic roles of several MT-dependent motor enzymes and learn how the enzymes interact with one another and with MT assembly to effect orderly chromosome motion. ..
  7. KINESIN-LIKE MOTORS IN MITOTIC MOVEMENTS
    J McIntosh; Fiscal Year: 1993
    ..Through this combination of studies we hope to identify the mitotic roles of several MT-dependent motor enzymes and learn how the enzymes interact with one another and with MT assembly to effect orderly chromosome motion...
  8. MICROTUBULE DYNAMICS IN VIVO
    J McIntosh; Fiscal Year: 1992
    ..The role of Ca-calmodulin will be explored. Suggestive results from experiments in vivo will be used to design polymerization experiments in vitro to analyze regulatory phenomena in a more specifically defined environment...
  9. Biophysics of the morphology and motility of Borrelia burgdorferi in diverse envi
    Charles W Wolgemuth; Fiscal Year: 2010
    ....