squalus acanthias

Summary

Summary: A species of shark in the family SQUALIDAE, used for its oil (SQUALENE) and as fish meal. It also figures heavily in biological research, especially with reference to its RECTAL GLAND in studies of WATER-ELECTROLYTE BALANCE.

Top Publications

  1. pmc RNA expression in a cartilaginous fish cell line reveals ancient 3' noncoding regions highly conserved in vertebrates
    David Forest
    Mount Desert Island Biological Laboratory, Salisbury Cove, ME 04672, USA
    Proc Natl Acad Sci U S A 104:1224-9. 2007
  2. pmc Analysis and functional annotation of expressed sequence tags from in vitro cell lines of elasmobranchs: Spiny dogfish shark (Squalus acanthias) and little skate (Leucoraja erinacea)
    Angela Parton
    Mount Desert Island Biological Laboratory, Salisbury Cove, Maine 04672, USA
    Comp Biochem Physiol Part D Genomics Proteomics 5:199-206. 2010
  3. pmc An acid-sensing ion channel from shark (Squalus acanthias) mediates transient and sustained responses to protons
    Andreas Springauf
    Department of Physiology, RWTH Aachen University, Pauwelsstrasse 30, D 52074 Aachen, Germany
    J Physiol 588:809-20. 2010
  4. ncbi The dogfish shark (Squalus acanthias) increases both hepatic and extrahepatic ornithine urea cycle enzyme activities for nitrogen conservation after feeding
    Makiko Kajimura
    Department of Biology, McMaster University, Hamilton, Ontario, Canada
    Physiol Biochem Zool 79:602-13. 2006
  5. doi Frequency of multiple paternity in the spiny dogfish Squalus acanthias in the western north Atlantic
    Ana Veríssimo
    Department of Fisheries Science, Virginia Institute of Marine Science, College of William and Mary, Gloucester Point, VA 23062, USA
    J Hered 102:88-93. 2011
  6. ncbi Osmoregulation, ionoregulation and acid-base regulation by the gastrointestinal tract after feeding in the elasmobranch (Squalus acanthias)
    Chris M Wood
    Department of Biology, McMaster University, 1280 Main St West, Hamilton, Ontario, L8S 4K1, Canada
    J Exp Biol 210:1335-49. 2007
  7. ncbi Microtubule-dependent relocation of branchial V-H+-ATPase to the basolateral membrane in the Pacific spiny dogfish (Squalus acanthias): a role in base secretion
    Martin Tresguerres
    Dept of Biological Sciences, University of Alberta, Edmonton, Alberta, T5G 2E9, Canada
    J Exp Biol 209:599-609. 2006
  8. doi Gene structure and functional characterization of growth hormone in dogfish, Squalus acanthias
    Shunsuke Moriyama
    School of Fisheries Sciences, Kitasato University, Sanriku, Iwate, Japan
    Zoolog Sci 25:604-13. 2008
  9. ncbi The putative mechanism of Na(+) absorption in euryhaline elasmobranchs exists in the gills of a stenohaline marine elasmobranch, Squalus acanthias
    Keith P Choe
    Department of Zoology, University of Florida, Gainesville, FL 32611, USA
    Comp Biochem Physiol A Mol Integr Physiol 146:155-62. 2007
  10. ncbi Regulation of branchial V-H(+)-ATPase, Na(+)/K(+)-ATPase and NHE2 in response to acid and base infusions in the Pacific spiny dogfish (Squalus acanthias)
    Martin Tresguerres
    Department of Biological Sciences, University of Alberta, Edmonton, Alberta T5G 2E9, Canada
    J Exp Biol 208:345-54. 2005

Research Grants

Detail Information

Publications125 found, 100 shown here

  1. pmc RNA expression in a cartilaginous fish cell line reveals ancient 3' noncoding regions highly conserved in vertebrates
    David Forest
    Mount Desert Island Biological Laboratory, Salisbury Cove, ME 04672, USA
    Proc Natl Acad Sci U S A 104:1224-9. 2007
    We have established a cartilaginous fish cell line [Squalus acanthias embryo cell line (SAE)], a mesenchymal stem cell line derived from the embryo of an elasmobranch, the spiny dogfish shark S. acanthias...
  2. pmc Analysis and functional annotation of expressed sequence tags from in vitro cell lines of elasmobranchs: Spiny dogfish shark (Squalus acanthias) and little skate (Leucoraja erinacea)
    Angela Parton
    Mount Desert Island Biological Laboratory, Salisbury Cove, Maine 04672, USA
    Comp Biochem Physiol Part D Genomics Proteomics 5:199-206. 2010
    ..Previously we developed cell lines from embryos of two elasmobranchs, Squalus acanthias the spiny dogfish shark (SAE line), and Leucoraja erinacea the little skate (LEE-1 line)...
  3. pmc An acid-sensing ion channel from shark (Squalus acanthias) mediates transient and sustained responses to protons
    Andreas Springauf
    Department of Physiology, RWTH Aachen University, Pauwelsstrasse 30, D 52074 Aachen, Germany
    J Physiol 588:809-20. 2010
    ..Our results show that the conservation of the amino acids crucial for proton gating can predict proton sensitivity of an ASIC and increase our understanding of the evolution of ASICs...
  4. ncbi The dogfish shark (Squalus acanthias) increases both hepatic and extrahepatic ornithine urea cycle enzyme activities for nitrogen conservation after feeding
    Makiko Kajimura
    Department of Biology, McMaster University, Hamilton, Ontario, Canada
    Physiol Biochem Zool 79:602-13. 2006
    ..effect of feeding, and thus elevated nitrogen intake, on nitrogen metabolism in the Pacific spiny dogfish Squalus acanthias. We determined the activities of ornithine urea cycle (O-UC) and related enzymes in liver and nonhepatic ..
  5. doi Frequency of multiple paternity in the spiny dogfish Squalus acanthias in the western north Atlantic
    Ana Veríssimo
    Department of Fisheries Science, Virginia Institute of Marine Science, College of William and Mary, Gloucester Point, VA 23062, USA
    J Hered 102:88-93. 2011
    ..In the squaloid shark Squalus acanthias, MP has been reported, but whether it is a common feature of the species' reproductive strategy is unknown...
  6. ncbi Osmoregulation, ionoregulation and acid-base regulation by the gastrointestinal tract after feeding in the elasmobranch (Squalus acanthias)
    Chris M Wood
    Department of Biology, McMaster University, 1280 Main St West, Hamilton, Ontario, L8S 4K1, Canada
    J Exp Biol 210:1335-49. 2007
    ..Our results illustrate the complex integration of digestive and ionoregulatory function in the elasmobranch digestive tract, and marked differences from the teleost pattern...
  7. ncbi Microtubule-dependent relocation of branchial V-H+-ATPase to the basolateral membrane in the Pacific spiny dogfish (Squalus acanthias): a role in base secretion
    Martin Tresguerres
    Dept of Biological Sciences, University of Alberta, Edmonton, Alberta, T5G 2E9, Canada
    J Exp Biol 209:599-609. 2006
    ..Our results strongly suggest that cellular relocation of V-H+-ATPase is necessary for enhanced HCO3- secretion across the gills of the Pacific dogfish...
  8. doi Gene structure and functional characterization of growth hormone in dogfish, Squalus acanthias
    Shunsuke Moriyama
    School of Fisheries Sciences, Kitasato University, Sanriku, Iwate, Japan
    Zoolog Sci 25:604-13. 2008
    Dogfish (Squalus acanthias) growth hormone (GH) was identified by cDNA cloning and protein purification from the pituitary gland. Dogfish GH cDNA encoded a prehormone of 210 amino acids (aa)...
  9. ncbi The putative mechanism of Na(+) absorption in euryhaline elasmobranchs exists in the gills of a stenohaline marine elasmobranch, Squalus acanthias
    Keith P Choe
    Department of Zoology, University of Florida, Gainesville, FL 32611, USA
    Comp Biochem Physiol A Mol Integr Physiol 146:155-62. 2007
    ..NHE3 antibody was used to localize the exchanger in the gills of the stenohaline marine spiny dogfish shark (Squalus acanthias)...
  10. ncbi Regulation of branchial V-H(+)-ATPase, Na(+)/K(+)-ATPase and NHE2 in response to acid and base infusions in the Pacific spiny dogfish (Squalus acanthias)
    Martin Tresguerres
    Department of Biological Sciences, University of Alberta, Edmonton, Alberta T5G 2E9, Canada
    J Exp Biol 208:345-54. 2005
    ..Western analysis in gill membranes from HCl-infused fish also revealed increased abundance of Na(+)/H(+) exchanger 2 (213+/-5%) and Na(+)/K(+)-ATPase (315+/-88%) compared to the control...
  11. ncbi Stage and season effects on cell cycle and apoptotic activities of germ cells and Sertoli cells during spermatogenesis in the spiny dogfish (Squalus acanthias)
    L M McClusky
    Department of Physiology, Faculty of Health Sciences, University of Pretoria, P O Box 2034, Pretoria 0001, South Africa
    Reproduction 129:89-102. 2005
    To understand the processes involved in the spatial and temporal maturation of testicular cells in Squalus acanthias, we used standard morphometry, proliferating-cell nuclear antigen (PCNA) and terminal deoxynucleotidyl transferase-..
  12. ncbi Alkaline tide and nitrogen conservation after feeding in an elasmobranch (Squalus acanthias)
    Chris M Wood
    Department of Biology, McMaster University, 1280 Main St West, Hamilton, Ontario, Canada L8S 4K1
    J Exp Biol 208:2693-705. 2005
    ....
  13. ncbi Selective permeability barrier to urea in shark rectal gland
    Joshua D Zeidel
    Laboratory of Epithelial Cell Biology, Renal Electrolyte Division, Dept of Medicine, University of Pittsburgh School of Medicine, PA 15215, USA
    Am J Physiol Renal Physiol 289:F83-9. 2005
    ..These results indicate that the rectal gland maintains a selective barrier to urea in its basolateral membranes...
  14. ncbi Copper toxicity in the spiny dogfish (Squalus acanthias): urea loss contributes to the osmoregulatory disturbance
    G De Boeck
    Ecophysiology, Biochemistry and Toxicology Group, Department of Biology, University of Antwerp, Groenenborgerlaan 171, B 2020 Antwerp, Belgium
    Aquat Toxicol 84:133-41. 2007
    Previous research showed that the spiny dogfish, Squalus acanthias, is much more sensitive to silver exposure than typical marine teleosts...
  15. ncbi A single glutamine synthetase gene produces tissue-specific subcellular localization by alternative splicing
    Gideon D Matthews
    Department of Biochemistry, George S Wise Faculty of Life Sciences, Tel Aviv University, Israel
    FEBS Lett 579:5527-34. 2005
    ..Here we show that in the ureosmotic elasmobranch, Squalus acanthias (spiny dogfish), two different GS transcripts are generated by tissue-specific alternative splicing...
  16. doi Is the alkaline tide a signal to activate metabolic or ionoregulatory enzymes in the dogfish shark (Squalus acanthias)?
    Chris M Wood
    Department of Biology, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada
    Physiol Biochem Zool 81:278-87. 2008
    ..We conclude that both the alkaline tide and salt loading/volume expansion act as signals to activate some but not all of the elevated metabolic pathways and ionoregulatory mechanisms needed during processing of a meal...
  17. ncbi Molecular detection and immunological localization of gill Na+/H+ exchanger in the dogfish (Squalus acanthias)
    James B Claiborne
    Department of Biology, Georgia Southern University, Statesboro, GA 30460, USA
    Am J Physiol Regul Integr Comp Physiol 294:R1092-102. 2008
    The dogfish (Squalus acanthias) can make rapid adjustments to gill acid-base transfers to compensate for internal acidosis/alkalosis...
  18. ncbi Characterization of a novel interaction between the secretory Na+-K+-Cl- cotransporter and the chaperone hsp90
    Charles F Simard
    Nephrology Research Group, Department of Medicine, Faculty of Medicine, Laval University, Quebec, Canada G1R 2J6
    J Biol Chem 279:48449-56. 2004
    ..Further studies will be required to elucidate the functional relevance of this novel interaction...
  19. ncbi Cadmium accumulation and binding characteristics in intact Sertoli/germ cell units, and associated effects on stage-specific functions in vitro: insights from a shark testis model
    Leon M McClusky
    Department of Physiology, Faculty of Health Sciences, University of Pretoria, P O Box 2034, Pretoria, South Africa
    J Appl Toxicol 28:112-21. 2008
    ..These findings demonstrate that this model has utility for use in screening assays of environmental toxicants...
  20. ncbi Stage-dependency of apoptosis and the blood-testis barrier in the dogfish shark (Squalus acanthias): cadmium-induced changes as assessed by vital fluorescence techniques
    Leon M McClusky
    Department of Physiology, Faculty of Health Sciences, University of Pretoria, P O Box 2034 Pretoria, South Africa
    Cell Tissue Res 325:541-53. 2006
    ..Sharks such as Squalus acanthias provide a suitable model for studying aspects of vertebrate spermatogenosis because of their unique features:..
  21. ncbi The effects of endothelin-1 on the cardiorespiratory physiology of the freshwater trout (Oncorhynchus mykiss) and the marine dogfish (Squalus acanthias)
    S F Perry
    Department of Biology, University of Ottawa, Ontario, Canada
    J Comp Physiol B 171:623-34. 2001
    ..on respiratory gas transfer in the freshwater rainbow trout (Oncorhynchus mykiss) and the marine dogfish (Squalus acanthias). In both species, endothelin-1 (666 pmol kg(-1)) caused a rapid (within 4 min) reduction (ca...
  22. pmc Glutamine-dependent carbamoyl-phosphate synthetase and other enzyme activities related to the pyrimidine pathway in spleen of Squalus acanthias (spiny dogfish)
    P M Anderson
    Department of Biochemistry, University of Minnesota, Duluth 55812
    Biochem J 261:523-9. 1989
    ..the enzymology of carbamoyl phosphate formation and utilization for pyrimidine nucleotide biosynthesis in Squalus acanthias (spiny dogfish), a representative elasmobranch...
  23. ncbi The relative roles of external and internal CO(2) versus H(+) in eliciting the cardiorespiratory responses of Salmo salar and Squalus acanthias to hypercarbia
    S F Perry
    Department of Biology, University of Ottawa, 30 Marie Curie, Ottawa, Ontario, Canada K1N 6N5
    J Exp Biol 204:3963-71. 2001
    ..relative contributions of CO(2) versus H(+) in promoting the cardiorespiratory responses of dogfish (Squalus acanthias) and Atlantic salmon (Salmo salar) to hypercarbia and to evaluate the relative contributions of externally ..
  24. ncbi Cardiovascular control via angiotensin II and circulating catecholamines in the spiny dogfish, Squalus acanthias
    N J Bernier
    Bamfield Marine Station, Vancouver Island, British Columbia, Canada
    J Comp Physiol B 169:237-48. 1999
    ..However, during a hypotensive stress elicited by vascular smooth muscle relaxation. Ang II indirectly contributes to cardiovascular control by dose-dependently stimulating catecholamine release...
  25. ncbi Secretion of endolymph by semicircular canals of the shark
    J L Garvin
    Laboratory of Kidney and Electrolyte Metabolism, National Institutes of Health, Bethesda, Maryland 20892
    Am J Physiol 255:F711-9. 1988
    The semicircular canals of the vestibular labyrinth of the dogfish shark, Squalus acanthias, may serve as a simple in vitro system for the study of the ionic transport mechanisms involved in endolymph formation...
  26. ncbi Myocardial oxygen consumption and mechanical efficiency of a perfused dogfish heart preparation
    P S Davie
    Department of Physiology and Anatomy, Massey University, Palmerston North, New Zealand
    J Comp Physiol B 162:256-62. 1992
    Oxygen consumption of an in-pericardium heart preparation from the spiny dogfish (Squalus acanthias) was linearly related to cardiac power output. Basal oxygen consumption, predicted from the regression, was 0.127 microliters.s-1...
  27. ncbi pCMBS-induced swelling of dogfish (Squalus acanthias) rectal gland cells: role of the Na+,K(+)-ATPase and the cytoskeleton
    A Kleinzeller
    Department of Physiology, University of Pennsylvania, Philadelphia 19104 6085
    Biochim Biophys Acta 1025:21-31. 1990
    ..sulfonate (pCMBS) and some other organic mercurials produce a swelling of slices of dogfish shark (Squalus acanthias) rectal glands, with an uptake of cell Na+ and a loss of K+...
  28. ncbi V-H+ -ATPase translocation during blood alkalosis in dogfish gills: interaction with carbonic anhydrase and involvement in the postfeeding alkaline tide
    Martin Tresguerres
    Dept of Biological Sciences, Univ of Alberta, Edmonton, Alberta, Canada
    Am J Physiol Regul Integr Comp Physiol 292:R2012-9. 2007
    ..anhydrase (CA) in mediating V-H(+)-ATPase translocation into the basolateral membrane in gills of alkalotic Squalus acanthias. Immunolabeling revealed that CA is localized in the same cells as V-H(+)-ATPase...
  29. ncbi Vasoactivity and immunoreactivity of fish tachykinins in the vascular system of the spiny dogfish
    J Kagstrom
    Department of Zoophysiology, Goteborg University, Sweden
    Am J Physiol 270:R585-93. 1996
    ..pulsed Doppler technique), dorsal aortic pressure, and heart rate were studied in unrestrained spiny dogfish Squalus acanthias injected with the elasmobranch tachykinins scyliorhinin I and II (SCY I and SCY II), the trout tachykinins ..
  30. ncbi Further evidence for ancient role of ACTH peptides at melanocortin (MC) receptors; pharmacology of dogfish and lamprey peptides at dogfish MC receptors
    Tatjana Haitina
    Department of Neuroscience, Unit of Pharmacology, Uppsala University, BMC, SE 75124 Uppsala, Sweden
    Peptides 28:798-805. 2007
    ..paper we synthesized melanocortin peptides from both the sea lamprey (Petromyzon marinus) and spiny dogfish (Squalus acanthias) and tested them on the MC3 and MC4 receptors from spiny dogfish...
  31. ncbi 28S and 18S rDNA sequences support the monophyly of lampreys and hagfishes
    J Mallatt
    Department of Zoology, Washington State University, Pullman 99164 4236, USA
    Mol Biol Evol 15:1706-18. 1998
    ..hagfish Eptatretus stouti, the lamprey Petromyzon marinus, and cartilaginous fishes Hydrolagus colliei and Squalus acanthias and were then analyzed with previously reported 28S and 18S rDNA sequences from other chordates...
  32. ncbi Sensitivity of the spiny dogfish (Squalus acanthias) to waterborne silver exposure
    G De Boeck
    Department of Biology, McMaster University, 1280 Main Street West, Hamilton, Ont, Canada L8S 4K1
    Aquat Toxicol 54:261-75. 2001
    The physiological effects of waterborne silver exposure (added as AgNO(3)) on spiny dogfish, Squalus acanthias, were evaluated at 30, 200 and 685 microg silver per l in 30 per thousand seawater...
  33. ncbi GFAP-immunopositive structures in spiny dogfish, Squalus acanthias, and little skate, Raia erinacea, brains: differences have evolutionary implications
    M Kalman
    Department of Anatomy, Histology and Embryology, Semmelweis University, Budapest, Hungary
    Anat Embryol (Berl) 204:59-80. 2001
    GFAP expression patterns were compared between the brains of a spiny dogfish (Squalus acanthias) and a little skate (Raia erinacea). After anesthesia, the animals were perfused with paraformaldehyde...
  34. ncbi The modulatory effects of noradrenaline on vagal control of heart rate in the dogfish, Squalus acanthias
    Claudio Agnisola
    Bamfield Marine Station, Vancouver Island, British Columbia V0R 1B0, Canada
    Physiol Biochem Zool 76:310-20. 2003
    ..between inhibitory vagal control of the heart and circulating levels of catecholamines in dogfish (Squalus acanthias) were studied using an in situ preparation of the heart, which retained intact its innervation from ..
  35. ncbi Nephrogenesis is induced by partial nephrectomy in the elasmobranch Leucoraja erinacea
    Marlies Elger
    Department of Nephrology, Hannover Medical School, Hannover, Germany
    J Am Soc Nephrol 14:1506-18. 2003
    ..Am J Anat 190: 309-333, 1991), as well as in the spiny dogfish Squalus acanthias and the little skate, Leucoraja erinacea...
  36. ncbi Urea and water permeability in dogfish (Squalus acanthias) gills
    P Part
    Department of Environmental Toxicology, Uppsala University, Norbyvagen 18A, Sweden
    Comp Biochem Physiol A Mol Integr Physiol 119:117-23. 1998
    ....
  37. ncbi Neural control of shark rectal gland
    J S Stoff
    Mount Desert Island Biological Laboratory, Salsbury Cove, Maine 04672
    Am J Physiol 255:R212-6. 1988
    Veratrum alkaloids stimulated salt secretion by the isolated perfused rectal gland of Squalus acanthias. Stimulation by veratrine was prevented by the nerve channel blockers tetrodotoxin and procaine and was not evident in a preparation ..
  38. ncbi Autocrine and paracrine role of steroids during spermatogenesis: studies in Squalus acanthias and Necturus maculosus
    G V Callard
    Department of Biology, Boston University, Massachusetts 02215
    J Exp Zool 261:132-42. 1992
    Due to a cystic mode of spermatogenesis and zonal testes, the spiny dogfish shark (Squalus acanthias) and salamander (Necturus maculosus) are advantageous for studying the relationship between steroidogenesis and germ cell development...
  39. ncbi A phase I and pharmacokinetic study of squalamine, a novel antiangiogenic agent, in patients with advanced cancers
    P Bhargava
    Lombardi Cancer Center, Georgetown University Medical Center, Washington, DC 20007, USA
    Clin Cancer Res 7:3912-9. 2001
    A Phase I study of squalamine, a novel antiangiogenic agent originally isolated from the dogfish shark Squalus acanthias, was conducted in patients with advanced cancers to: (a) determine the maximum tolerated dose (MTD), dose-limiting ..
  40. ncbi Type IV carbonic anhydrase is present in the gills of spiny dogfish (Squalus acanthias)
    K M Gilmour
    Department of Biology, University of Ottawa, 30 Marie Curie, Ottawa, ON, Canada K1N 6N5
    Am J Physiol Regul Integr Comp Physiol 292:R556-67. 2007
    ..carbonic anhydrase (CA) isoform, similar to mammalian type IV CA, in the gills of dogfish (Squalus acanthias)...
  41. ncbi The effect of mercury on chloride secretion in the shark (Squalus acanthias) rectal gland
    P Silva
    Department of Medicine, New England Deaconess Hospital
    Comp Biochem Physiol C 103:569-75. 1992
    ....
  42. ncbi Reproductive endocrinology of female elasmobranchs: lessons from the little skate (Raja erinacea) and spiny dogfish (Squalus acanthias)
    T J Koob
    Skeletal Biology, Shriners Hospital for Children, Tampa, Florida 33612, USA
    J Exp Zool 284:557-74. 1999
    ..An understanding of the adaptations in ovarian dynamics to particular ovulatory cycles is key to developing theories about the evolution of reproductive strategies in female elasmobranchs. J. Exp. Zool. 284:557-574, 1999...
  43. ncbi Transepithelial organic anion transport by shark choroid plexus
    Alice R A Villalobos
    Mount Desert Island Biological Laboratory, Salisbury Cove, Maine 04672, USA
    Am J Physiol Regul Integr Comp Physiol 282:R1308-16. 2002
    Spiny dogfish shark (Squalus acanthias) lateral and IV choroid plexuses (CPs) are ultrastructurally similar to the corresponding tissues of rat. However, shark IV CP is proportionally larger and easily accessible...
  44. ncbi Control of rectal gland secretion by blood acid-base status in the intact dogfish shark (Squalus acanthias)
    Chris M Wood
    Department of Biology, McMaster University, 1280 Main St West, Hamilton, Ontario, Canada L8S 4K1
    Respir Physiol Neurobiol 156:220-8. 2007
    ....
  45. ncbi ETB-type receptors mediate endothelin-stimulated contraction in the aortic vascular smooth muscle of the spiny dogfish shark, Squalus acanthias
    D H Evans
    Mt Desert Island Biological Laboratory, Salsbury Cove, ME 04672, USA
    J Comp Physiol B 165:659-64. 1996
    ..the sensitivity to endothelin of the vascular smooth muscle of the ventral aorta of the spiny dogfish shark, Squalus acanthias. Human endothelin-1 produced significant contraction of isolated vascular smooth muscle rings, with an EC50 ..
  46. ncbi Neuropeptide control of the cardiovascular system in fish and reptiles
    S Holmgren
    Department of Zoophysiology, University of Goteborg, Sweden
    Braz J Med Biol Res 28:1207-16. 1995
    ..cod (Gadus morhua) as in most mammalian species, but increases gut vascular resistance in the spiny dogfish (Squalus acanthias)...
  47. ncbi Feeding ecology of five commercial shark species of the Celtic Sea through stable isotope and trace metal analysis
    N Domi
    Marine Research Center MARE, Laboratory for Oceanology, University of Liege, B6c Sart Tilman, B 4000 Liege, Belgium
    Mar Environ Res 60:551-69. 2005
    ..the black-mouthed catshark Galeus melastomus, the starry smooth hound Mustelus asterias, the spiny dogfish Squalus acanthias and the lesser-spotted dogfish Scyliorhinus canicula...
  48. ncbi Branchial CO(2) receptors and cardiorespiratory adjustments during hypercarbia in Pacific spiny dogfish (Squalus acanthias)
    J E McKendry
    Department of Biology, University of Ottawa, Ottawa, Ontario, Canada K1N 6N5
    J Exp Biol 204:1519-27. 2001
    Adult Pacific spiny dogfish (Squalus acanthias) were exposed to acute (approximately 20 min) hypercarbia while we monitored arterial blood pressure, systemic vascular resistance (R(S)), cardiac output (V(b)) and frequency (fh) as well as ..
  49. ncbi Accurate determination of Cd, Cr, Cu and Ni in woodlice and their skins--is moulting a means of detoxification?
    Michael Raessler
    Max Planck Institut fuer Biogeochemie, ChemLab, Hans Knoell Strasse 10, D 07745 Jena, Germany
    Sci Total Environ 337:83-90. 2005
    ..To match the matrix of the samples very closely, the reference materials Dorm-2, Dogfish Muscle (Squalus acanthias) and SRM 1577b Bovine Liver were used to evaluate the whole analytical process including sample digestion...
  50. ncbi Escape manoeuvres in the spiny dogfish (Squalus acanthias)
    Paolo Domenici
    CNR IAMC, c o International Marine Centre, Loc Sa Mardini, 09072 Torregrande, Oristano, Italy
    J Exp Biol 207:2339-49. 2004
    ....
  51. ncbi A facilitative urea transporter is localized in the renal collecting tubule of the dogfish Triakis scyllia
    Susumu Hyodo
    Laboratory of Physiology, Ocean Research Institute, University of Tokyo, 1 15 1 Minamidai, Nakano, Tokyo 164 8639, Japan
    J Exp Biol 207:347-56. 2004
    ..isolated a cDNA encoding a UT that is homologous to the facilitative UT cloned from another dogfish species, Squalus acanthias. The Triakis UT mRNA is abundantly expressed in the kidney, while low levels of expression were detected in ..
  52. ncbi Characterization of an endothelin ET(B) receptor in the gill of the dogfish shark Squalus acanthias
    D H Evans
    Department of Zoology, University of Florida, Gainesville, FL 32611, USA
    J Exp Biol 202:3605-10. 1999
    ..kinetics of (125)I-labeled, human ET-1 to membrane fragments isolated from the gill of the dogfish shark, Squalus acanthias. (125)I-ET-1 bound at a single site, with a dissociation constant (K(d)) and binding site number (B(max)) ..
  53. pmc Characterization of the shark myelin Po protein
    L Rotenstein
    California State University Northridge, Biology Department, Northridge, Calif, USA
    Brain Behav Evol 72:48-58. 2008
    ..We found that sharks have more than two isoforms (32, 28 and 25 kD), and that some of these might not be fully functional because they lack the domains known for Po homophilic adhesion...
  54. ncbi Endothelin B receptor Ca2+ signaling in shark vascular smooth muscle: participation of inositol trisphosphate and ryanodine receptors
    Susan K Fellner
    Department of Cell and Molecular Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    J Exp Biol 207:3411-7. 2004
    ..measured cytosolic Ca(2+) concentration ([Ca(2+)](i)) in fura-2-loaded VSM of anterior mesenteric artery of Squalus acanthias and show that the ET(B)R agonists IRL 1620 and sarafotoxin S6c (SRX) increase [Ca(2+)](i) in VSM to the same ..
  55. pmc Multidrug resistance-associated protein 3 (Mrp3/Abcc3/Moat-D) is expressed in the SAE Squalus acanthias shark embryo-derived cell line
    Hiroshi Kobayashi
    Mount Desert Island Biological Laboratory, Salisbury Cove, Maine 04672, USA
    Zebrafish 4:261-75. 2007
    ..We have derived from the embryo of Squalus acanthias, the spiny dogfish shark, the S. acanthias embryo (SAE) mesenchymal stem cell line...
  56. ncbi Central venous pressure and mean circulatory filling pressure in the dogfish Squalus acanthias: adrenergic control and role of the pericardium
    Erik Sandblom
    Dept of Zoology, Göteborg Univ, Box 463, Goteborg S 405 30, Sweden
    Am J Physiol Regul Integr Comp Physiol 291:R1465-73. 2006
    ..Venous capacitance was estimated in the dogfish Squalus acanthias by measuring the mean circulatory filling pressure (MCFP) during transient occlusion of cardiac outflow...
  57. ncbi Adenosine/nitric oxide crosstalk in the branchial circulation of Squalus acanthias and Anguilla anguilla
    D Pellegrino
    Department of Pharmaco Biology, University of Calabria, 87030 Arcavacata di Rende, CS, Italy
    Comp Biochem Physiol A Mol Integr Physiol 142:198-204. 2005
    ..the actions of AD in fish, we have analysed this question in the branchial vasculature of the elasmobranch Squalus acanthias and the teleost Anguilla anguilla using an isolated perfused head and a branchial basket preparation, ..
  58. ncbi Na(+)-D-glucose cotransporter in the kidney of Squalus acanthias: molecular identification and intrarenal distribution
    Thorsten Althoff
    Max Planck Institut fur molekulare Physiologie, Abteilung Epithelphysiologie, Otto Hahn Strasse 11, 44227 Dortmund, Germany
    Am J Physiol Regul Integr Comp Physiol 290:R1094-104. 2006
    ..mammalian Na(+)-d-glucose cotransporters (SGLT), a cDNA was cloned from the kidney of spiny dogfish shark (Squalus acanthias)...
  59. pmc Isolation of anti-toxin single domain antibodies from a semi-synthetic spiny dogfish shark display library
    Jinny L Liu
    Center for Bio Molecular Science and Engineering, Code 6920, Naval Research Laboratory, 4555 Overlook Ave, SW, Washington, DC 20375, USA
    BMC Biotechnol 7:78. 2007
    ..In this report, we construct and characterize a diversity enhanced semi-synthetic NAR V display library based on naturally occurring NAR V sequences...
  60. doi Fetal bovine serum simultaneously stimulates apoptosis and DNA synthesis in premeiotic stages of spermatogenesis in spiny dogfish (Squalus acanthias) in vitro: modulation by androgen and spermatogenic activity status
    Leon Mendel McClusky
    Department of Health and Nursing Science, Narvik University College, P O Box 385, Narvik 8505, Norway
    Apoptosis 13:649-58. 2008
    ..Results are discussed in the context of the alternating germ-Sertoli cell population kinetics of early-stage spermatogonial cysts in Squalus acanthias's protracted testicular cycle.
  61. doi An evolutionary view on tooth development and replacement in wild Atlantic salmon (Salmo salar L.)
    A Huysseune
    Biology Department, Ghent University, B 9000 Ghent, Belgium
    Evol Dev 10:6-14. 2008
    ..of tooth replacement in Atlantic salmon displays several characters similar to those observed in the shark Squalus acanthias. To interpret similarities in tooth replacement between Atlantic salmon and chondrichthyans as a case of ..
  62. ncbi The synthesis of spermine analogs of the shark aminosterol squalamine
    Youheng Shu
    Chemistry Department, Villanova University, Villanova, PA 19085, USA
    Steroids 67:291-304. 2002
    Aminosterols isolated from the dogfish shark Squalus acanthias are promising therapeutic agents in the treatment of infection and cancer...
  63. pmc Divergent CFTR orthologs respond differently to the channel inhibitors CFTRinh-172, glibenclamide, and GlyH-101
    Maximilian Stahl
    Nephrology Division, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06510 3222, USA
    Am J Physiol Cell Physiol 302:C67-76. 2012
    ....
  64. pmc Trophic interactions and distribution of some Squaliforme sharks, including new diet descriptions for Deania calcea and Squalus acanthias
    Matthew R Dunn
    School of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand
    PLoS ONE 8:e59938. 2013
    ..The diets of 133 Deania calcea and 295 Squalus acanthias were determined from examination of stomach contents. The diet of D...
  65. doi Morphological features of coronary arteries and lesions in hearts from five species of sharks collected from the northwestern Atlantic Ocean
    J D Borucinska
    Department of Biology, University of Hartford, West Hartford, CT 06117 1559, USA
    J Fish Dis 35:741-53. 2012
    ..the smooth dogfish, Mustelus canis (Mitchill), and spiny dogfish, Squalus acanthias L. Sharks were collected from the northwestern Atlantic between June and August from 1996 to 2010...
  66. ncbi Three neuropeptide Y receptor genes in the spiny dogfish, Squalus acanthias, support en bloc duplications in early vertebrate evolution
    Erik Salaneck
    Department of Neuroscience, Unit of Pharmacology, Evolutionary Biology Center, Uppsala University, Uppsala, Sweden
    Mol Biol Evol 20:1271-80. 2003
    ..the cloning of three neuropeptide Y (NPY) receptor genes belonging to the Y1 subfamily in the spiny dogfish, Squalus acanthias, a cartilaginous fish...
  67. pmc A structural view on the functional importance of the sugar moiety and steroid hydroxyls of cardiotonic steroids in binding to Na,K-ATPase
    Flemming Cornelius
    Department of Biomedicine, University of Aarhus, Ole Worms Allé 6, Building 1180, 8000 Aarhus C 8000, Denmark
    J Biol Chem 288:6602-16. 2013
    ..The results are discussed with reference to the recent crystal structures of Na,K-ATPase in the unbound and ouabain-bound states...
  68. ncbi Regulation of Na,K-ATPase by PLMS, the phospholemman-like protein from shark: molecular cloning, sequence, expression, cellular distribution, and functional effects of PLMS
    Yasser A Mahmmoud
    Department of Biophysics, University of Aarhus, Ole Worms Alle 185, DK 8000 Aarhus C, Denmark
    J Biol Chem 278:37427-38. 2003
    ..the complete coding sequence, expression, and cellular localization of PLMS in the rectal gland of the shark Squalus acanthias. The mature protein contained 74 amino acids, including the N-terminal FXYD motif and a C-terminal protein ..
  69. doi Forebrain organization in elasmobranchs
    Michael H Hofmann
    Department of Comparative Neuroanatomy, Institute of Zoology, University of Bonn, Germany
    Brain Behav Evol 80:142-51. 2012
    ..in two elasmobranch species: the thornback guitarfish, Platyrhinoidis triseriata, and the spiny dogfish, Squalus acanthias. Tracers were injected into various parts of the forebrain and olfactory pathways were found to be extensive ..
  70. doi Functional expression of Squalus acanthias melanocortin-5 receptor in CHO cells: ligand selectivity and interaction with MRAP
    Christina L Reinick
    University of Denver, Department of Biological Sciences, Denver, CO 80210, USA
    Eur J Pharmacol 680:1-7. 2012
    The melanocortin-5 receptor (MC(5)) of the dogfish Squalus acanthias (SacMC(5) receptor) can be functionally expressed in CHO cells in the absence of the co-expression of an exogenous MRAP cDNA...
  71. doi Characterisation and expression analysis of B-cell activating factor (BAFF) in spiny dogfish (Squalus acanthias): cartilaginous fish BAFF has a unique extra exon that may impact receptor binding
    Ronggai Li
    Scottish Fish Immunology Research Centre, University of Aberdeen, Zoology Building, Tillydrone Avenue, Aberdeen AB24 2TZ, Scotland, UK
    Dev Comp Immunol 36:707-17. 2012
    ..A BAFF gene has been cloned from spiny dogfish (Squalus acanthias) and its expression studied...
  72. ncbi Functional expression of recombinant spiny dogfish shark (Squalus acanthias) cytochrome P450c17 (17 alpha-hydroxylase/C17,20-lyase) in yeast (Pichia pastoris)
    J M Trant
    Department of Zoology and Physiology, Louisiana State University, Baton Rouge 70803, USA
    Arch Biochem Biophys 326:8-14. 1996
    The cDNA encoding the spiny dogfish shark (Squalus acanthias) testicular form of cytochrome P450c17 (CYP17) was used to direct the heterologous expression of a functional enzyme in yeast (Pichia pastoris)...
  73. pmc Arachidonic acid-induced expression of the organic solute and steroid transporter-beta (Ost-beta) in a cartilaginous fish cell line
    Jae Ho Hwang
    Mount Desert Island Biological Laboratory, Salisbury Cove, ME 04672, USA
    Comp Biochem Physiol C Toxicol Pharmacol 148:39-47. 2008
    ..for Ost-beta from skate liver, and the primary structure was identical to that of the spiny dogfish shark (Squalus acanthias) with the exception of a single amino acid...
  74. doi Evolutionary changes of astroglia in Elasmobranchii comparing to amniotes: a study based on three immunohistochemical markers (GFAP, S-100, and glutamine synthetase)
    Csilla Ari
    Department of Anatomy, Histology and Embryology, Semmelweis University, Budapest, Hungary
    Brain Behav Evol 71:305-24. 2008
    ..but not GFAP, characterized the Bergmann-glia of skates and rays and astrocyte-like non-ependymal cells in Squalus acanthias. Another squalomorph shark species, Pristiophorus cirratus, however, had GFAP immunopositive astrocytes...
  75. ncbi Immunohistochemical localization of bioactive peptides and amines associated with the chromaffin tissue of five species of fish
    S G Reid
    Department of Zoophysiology, University of Goteborg, Sweden
    Cell Tissue Res 280:499-512. 1995
    ..cod (Gadus morhua), rainbow trout (Oncorhynchus mykiss), European eel (Anguilla anguilla), spiny dogfish (Squalus acanthias) and Atlantic hagfish (Myxine glutinosa) were identified utilizing immunohistochemical techniques...
  76. ncbi Molecular cloning of a human cDNA encoding a trifunctional enzyme of carbamoyl-phosphate synthetase-aspartate transcarbamoylase-dihydroorotase in de Novo pyrimidine synthesis
    H Iwahana
    Otsuka Department of Clinical and Molecular Nutrition, University of Tokushima, Japan
    Biochem Biophys Res Commun 219:249-55. 1996
    ..The deduced amino acid sequence exhibits 95.3 and 76.1% identity with the CAD sequences of hamster and Squalus acanthias. The DNA fragment of 6,679 bp containing the full-length coding sequence was amplified by nested PCR using ..
  77. doi Evolution of gastrointestinal hormones: the cholecystokinin/gastrin family
    Graham S Baldwin
    Department of Surgery, The University of Melbourne, Austin Health, Heidelberg, Victoria, Australia
    Curr Opin Endocrinol Diabetes Obes 17:77-88. 2010
    ..To describe recent advances in our understanding of the evolution of gastrointestinal hormones, with the gastrin/cholecystokinin (CCK) family as a model...
  78. doi Using omeprazole to link the components of the post-prandial alkaline tide in the spiny dogfish, Squalus acanthias
    Chris M Wood
    Department of Biology, McMaster University, 1280 Main St West, Hamilton, Ontario, Canada
    J Exp Biol 212:684-92. 2009
    ....
  79. doi Expression of vitellogenin receptor in the ovarian follicles during the reproductive cycle of the spotted ray Torpedo marmorata Risso 1880
    Giuseppina Del Giudice
    Department of Biological Sciences, Evolutionary and Comparative Biology Division, University of Naples Federico II, Naples, Italy
    J Exp Zool A Ecol Genet Physiol 315:585-92. 2011
    ..shows a high identity with the VTGR of other vertebrates, particularly Leucoraja erinacea (89% identity) and Squalus acanthias (84% identity)...
  80. pmc A comparative study of the ocular skeleton of fossil and modern chondrichthyans
    Brettney L Pilgrim
    Biology Department, Memorial University of Newfoundland, St John s, Canada
    J Anat 214:848-58. 2009
    ..All three modern shark species examined (spiny dogfish shark Squalus acanthias, porbeagle shark Lamna nasus and blue shark Prionace glauca) have a continuous skeletal element that ..
  81. pmc Mechanisms of corneal tissue cross-linking in response to treatment with topical riboflavin and long-wavelength ultraviolet radiation (UVA)
    A Scott McCall
    Division of Biology, Kansas State University, Manhattan, Kansas 66506 4901, USA
    Invest Ophthalmol Vis Sci 51:129-38. 2010
    ..RFUVA treatment retards the progression of keratoconus, perhaps by cross-linking of collagen molecules, but exact molecular mechanisms remain unknown. Research described here tested possible chemical mechanisms of cross-linking...
  82. pmc Relationship between oxidizable fatty acid content and level of antioxidant glutathione peroxidases in marine fish
    Jeffrey M Grim
    Ohio University, Department of Biological Sciences, Athens, OH 45701, USA
    J Exp Biol 214:3751-9. 2011
    ..phospholipid composition in livers of five species of marine fish (Myxine glutinosa, Petromyzon marinus, Squalus acanthias, Fundulus heteroclitus and Myoxocephalus octodecemspinosus) that contain a range of PUFA...
  83. pmc Squalamine as a broad-spectrum systemic antiviral agent with therapeutic potential
    Michael Zasloff
    Transplant Institute, Department of Surgery, Georgetown University Medical Center, Washington, DC 20007, USA
    Proc Natl Acad Sci U S A 108:15978-83. 2011
    ..Here, we show that squalamine, a compound previously isolated from the tissues of the dogfish shark (Squalus acanthias) and the sea lamprey (Petromyzon marinus), exhibits broad-spectrum antiviral activity against human ..
  84. pmc Classification of sharks in the Egyptian Mediterranean waters using morphological and DNA barcoding approaches
    Marie Moftah
    Zoology Department, Faculty of Science, Alexandria University, Alexandria, Egypt
    PLoS ONE 6:e27001. 2011
    ..our knowledge to use DNA barcoding of the mitochondrial COI gene in order to confirm the presence of species Squalus acanthias, Oxynotus centrina, Squatina squatina, Scyliorhinus canicula, Scyliorhinus stellaris, Mustelus mustelus, ..
  85. doi Microsatellite loci within sixgill sharks, Hexanchus griseus
    Shawn Larson
    Seattle Aquarium, 1483 Alaskan Way, Pier 59, Seattle, WA 98101 2059, USA, Benaroya Research Institute at Virginia Mason, 1201 Ninth Ave, Seattle, WA 98101 2795, USA
    Mol Ecol Resour 9:978-81. 2009
    ..20-0.73, H(E)  = 0.59-0.94 and F(IS)  = -0.47-0.58), Pacific spiny dogfish (Squalus acanthias) (a = 3-13, H(O)  = 0.00-0.96, H(E)  = 0.24-0.93 and F(IS)  =-0.52-1...
  86. ncbi Evidence for the presence of A1 and A2 adenosine receptors in the ventral aorta of the dogfish shark, Squalus acanthias
    D H Evans
    Department of Zoology, University of Florida, Gainesville 32611
    J Comp Physiol B 162:179-83. 1992
    Isolated, endothelium-free rings of vascular smooth muscle (VSM) from the ventral aorta of the dogfish shark, Squalus acanthias, were used to examine the vasoactive effects of various adenosine agonists...
  87. doi Lipid correction model of carbon stable isotopes for a cosmopolitan predator, spiny dogfish Squalus acanthias
    J C P Reum
    School of Aquatic and Fisheries Sciences, University of Washington, Seattle, 1122 NE Boat St, Seattle, WA 98105, USA
    J Fish Biol 79:2060-6. 2011
    Three lipid correction models were evaluated for liver and white dorsal muscle from Squalus acanthias. For muscle, all three models performed well, based on the Akaike Information Criterion value corrected for small sample sizes (AIC(c) )..
  88. ncbi Global population structure of the spiny dogfish Squalus acanthias, a temperate shark with an antitropical distribution
    A Verissimo
    Virginia Institute of Marine Science, College of William and Mary, P O Box 1346, Gloucester Point, VA 23062, USA
    Mol Ecol 19:1651-62. 2010
    The spiny dogfish (Squalus acanthias) is a temperate, coastal squaloid shark with an antitropical distribution in the Atlantic and Pacific oceans...
  89. ncbi The effect of organotin compounds on chloride secretion by the in vitro perfused rectal gland of Squalus acanthias
    R Solomon
    Renal Division, New York Medical College, Valhalla 10595
    Toxicol Appl Pharmacol 100:307-14. 1989
    ..various organotins on membrane function and electrolyte transport were studied in the marine elasmobranch, Squalus acanthias. The isolated perfused rectal gland was used as a model of electrolyte transport...
  90. ncbi Natural feeding influences protein expression in the dogfish shark rectal gland: A proteomic analysis
    W Wesley Dowd
    Physiological Genomics Group, Animal Science Department, University of California, Davis, 1 Shields Ave, Davis, CA 95616 USA
    Comp Biochem Physiol Part D Genomics Proteomics 3:118-27. 2008
    ..response to natural feeding, we investigated protein-level responses in the rectal gland of spiny dogfish (Squalus acanthias) 6 h, 20 h, and 5 days (reference control) after a meal...
  91. doi The influence of feeding and fasting on plasma metabolites in the dogfish shark (Squalus acanthias)
    Chris M Wood
    Department of Biology, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada
    Comp Biochem Physiol A Mol Integr Physiol 155:435-44. 2010
    ....
  92. doi Urea-induced unfolding of Na,K-ATPase as evaluated by electron paramagnetic resonance spectroscopy
    Mohammad Babavali
    Department of Physiology and Biophysics, Aarhus University, Aarhus, Denmark
    Biochemistry 48:9022-30. 2009
    ..Susceptibility of the latter could arise from the nonhomologous regions in the cytoplasmic domain...
  93. pmc Texas Red transport across rat and dogfish shark (Squalus acanthias) choroid plexus
    Valeska Reichel
    Institute of Pharmacy and Molecular Biotechnology, INF 366, 69120 Heidelberg, Germany
    Am J Physiol Regul Integr Comp Physiol 295:R1311-9. 2008
    ..in lateral choroid plexus (CP) isolated from rat and an evolutionarily ancient vertebrate, dogfish shark (Squalus acanthias)...
  94. ncbi Identification of squalamine in the plasma membrane of white blood cells in the sea lamprey, Petromyzon marinus
    Sang Seon Yun
    Department of Fisheries and Wildlife, Michigan State University, East Lansing, MI 48824, USA
    J Lipid Res 48:2579-86. 2007
    ..in these fractions originated from squalamine, an aminosterol previously identified in the dogfish shark, Squalus acanthias. Further chromatographic and mass spectrometric analyses confirmed the identity of squalamine, an ..
  95. ncbi Contractile properties of the elasmobranch rectal gland
    D H Evans
    Department of Zoology, University of Florida, Gainesville, FL 32611, USA
    J Exp Biol 204:59-67. 2001
    ..To confirm the presence of the muscle ring, we examined histological sections from two species of shark, Squalus acanthias and Carcharodon carcharius, and from the stingray Dasyatis sabina and stained sections from S...
  96. ncbi Does stimulation of NaCl secretion in in vitro perfused rectal gland tubules of Squalus acanthias increase membrane capacitance?
    R Greger
    Physiologisches Institut, Albert Ludwigs Universitat, Hermann Herder Strasse 7, D 79104 Freiburg, Germany
    Pflugers Arch 436:538-44. 1998
    NaCl secretion in rectal gland tubules (RGT) of Squalus acanthias requires the activation of Cl– channels in the luminal membrane. The RGT and its mechanism of activation are an early evolutionary paradigm of exocrine secretion...
  97. ncbi A spermine-coupled cholesterol metabolite from the shark with potent appetite suppressant and antidiabetic properties
    M Zasloff
    Magainin Pharmaceuticals, Plymouth Meeting, Pennsylvania 19462, USA
    Int J Obes Relat Metab Disord 25:689-97. 2001
    ....
  98. ncbi Spatio-temporal and species-specific variation in PBDE levels/patterns in British Columbia's coastal waters
    Michael G Ikonomou
    Marine Environmental Quality, Institute of Ocean Sciences, Fisheries and Oceans Canada, 9860 W Saanich Road, Sidney, British Columbia V8L 4B2, Canada
    Environ Pollut 140:355-63. 2006
    ..muscle tissues of Dungeness crab (Cancer magister), English sole (Pleuronectes vetulus) and spiny dogfish (Squalus acanthias)...
  99. ncbi Extracellular carbonic anhydrase in the dogfish, Squalus acanthias: a role in CO2 excretion
    K M Gilmour
    Bamfield Marine Station, Bamfield, British Columbia V0R 1B0, Canada
    Physiol Biochem Zool 74:477-92. 2001
    In Pacific spiny dogfish (Squalus acanthias), plasma CO(2) reactions have access to plasma carbonic anhydrase (CA) and gill membrane-associated CA...
  100. ncbi Branchial mitochondria-rich cells in the dogfish Squalus acanthias
    Jonathan M Wilson
    Bamfield Marine Station, Bamfield, British Columbia, Canada
    Comp Biochem Physiol A Mol Integr Physiol 132:365-74. 2002
    ..under control conditions and following rectal gland removal (1 month) in the spiny dogfish, Squalus acanthias. A clear correlation can be made between MRC numbers and the levels of Na(+)/K(+)-ATPase activity in crude ..
  101. ncbi Interaction of FXYD10 (PLMS) with Na,K-ATPase from shark rectal glands. Close proximity of Cys74 of FXYD10 to Cys254 in the a domain of the alpha-subunit revealed by intermolecular thiol cross-linking
    Yasser Ahmed Mahmmoud
    Institute of Physiology and Biophysics, University of Aarhus, DK 8000 Aarhus C, Denmark
    J Biol Chem 280:27776-82. 2005
    ..Thus, regulation of Na,K-ATPase by FXYD10 occurs in part via cytoplasmic interaction of FXYD10 with the A domain of the shark alpha-subunit...

Research Grants31

  1. CELLULAR ASPECTS OF ACTIVE TRANSPORT
    Roy Forster; Fiscal Year: 1980
    ..in isolated renal tubules of the flounder (Pseudopleuronectus americanus) and in the dogfish shark (Squalus acanthias)...
  2. Cell and Molecular Biology of Marine Elasmobranchs
    David Barnes; Fiscal Year: 2004
    ..biological mechanisms of significance to human health, and world center for the use of the dogfish shark (Squalus acanthias) and little skate (Raja erinacea) as research models...
  3. Cell and Molecular Biology of Marine Elasmobranchs
    David Barnes; Fiscal Year: 2005
    ..biological mechanisms of significance to human health, and world center for the use of the dogfish shark (Squalus acanthias) and little skate (Raja erinacea) as research models...
  4. Cell and Molecular Biology of Marine Elasmobranchs
    David Barnes; Fiscal Year: 2006
    ..biological mechanisms of significance to human health, and world center for the use of the dogfish shark (Squalus acanthias) and little skate (Raja erinacea) as research models...
  5. CHLORIDE TRANSPORT AND OSMOREGULATION
    JOSE ZADUNAISKY; Fiscal Year: 1980
    ..cell-rich opercular epithelium of the teleost, Fundulus heteroclitus, the rectal gland of the dogfish shark, Squalus acanthias, and the cornea and pigment epithelium of the frog, Rana catesbiana...
  6. AHR signaling in Mammalian and Non-Mammalian Models
    MARK HAHN; Fiscal Year: 2005
    ..These studies will provide a better understanding of the possible role of human AHRR in modulating dioxin effects. ..
  7. The biology of gastrin-ferric ion complexes
    GRAHAM BALDWIN; Fiscal Year: 2006
    ..Recognition that metal ions are essential for the biological activity of NAGs may permit the development of novel therapies for colon cancer. ..
  8. AHR signaling in Mammalian and Non-Mammalian Models
    MARK HAHN; Fiscal Year: 2006
    ..These studies will provide a better understanding of the possible role of human AHRR in modulating dioxin effects. ..
  9. The biology of gastrin-ferric ion complexes
    GRAHAM BALDWIN; Fiscal Year: 2007
    ..Recognition that metal ions are essential for the biological activity of NAGs may permit the development of novel therapies for colon cancer. ..
  10. AHR signaling in Mammalian and Non-Mammalian Models
    MARK HAHN; Fiscal Year: 2007
    ..These studies will provide a better understanding of the possible role of human AHRR in modulating dioxin effects. ..
  11. The biology of gastrin-ferric ion complexes
    GRAHAM BALDWIN; Fiscal Year: 2008
    ..Recognition that metal ions are essential for the biological activity of NAGs may permit the development of novel therapies for colon cancer. ..
  12. The biology of gastrin-ferric ion complexes
    GRAHAM BALDWIN; Fiscal Year: 2009
    ..Recognition that metal ions are essential for the biological activity of NAGs may permit the development of novel therapies for colon cancer. ..
  13. Mechanisms of Embryo Response to Oxidative Stress
    MARK HAHN; Fiscal Year: 2009
    ....
  14. AHR signaling in Mammalian and Non-Mammalian Models
    Mark E Hahn; Fiscal Year: 2010
    ....
  15. Mechanisms of Embryo Response to Oxidative Stress
    Mark E Hahn; Fiscal Year: 2010
    ....
  16. MECHANISM AND REGULATION OF ACTIN-BASED RETROGRADE FLOW
    JOHN HENSON; Fiscal Year: 2005
    ..4. To study the inducible transformation of coelomocytes from a lamellipodial to a filopodial form. ..
  17. The biological activity of metal ion-gastrin complexes
    GRAHAM BALDWIN; Fiscal Year: 2004
    ..In the longer term definition of high affinity receptors for PDP-metal ion complexes may permit the development of novel therapies for treatment of disorders of iron metabolism and of gastrointestinal cancers. ..
  18. AH RECEPTOR IN NONMAMMALIAN MODELS
    MARK HAHN; Fiscal Year: 1999
    ..We will determine the diversity and function of AHR genes in fish species commonly used as aquatic models, test the hypothesis that a second AHR-like gene exists in humans, and compare the function of fish and human AHRs. ..
  19. AH RECEPTOR IN NON-MAMMALIAN MODELS
    MARK HAHN; Fiscal Year: 2000
    ..We will determine the diversity and function of AHR genes in fish species commonly used as aquatic models, test the hypothesis that a second AHR-like gene exists in humans, and compare the function of fish and human AHRs. ..
  20. MODULATION OF CHOROID PLEXUS CHOLINE TRANSPORT BY METALS
    Alice Villalobos; Fiscal Year: 2000
    ..abstract_text> ..
  21. STRESS MODULATION OF CHOLINE TRANSPORT BY CHOROID PLEXUS
    Alice Villalobos; Fiscal Year: 2001
    ..Therefore, a greater understanding of the energetics and modulation of medicated choline transport across the CSF-blood barrier would allow more effective prevention, management and treatment of such disorders. ..
  22. STRESS MODULATION OF CHOLINE TRANSPORT BY CHOROID PLEXUS
    Alice Villalobos; Fiscal Year: 2000
    ..Therefore, a greater understanding of the energetics and modulation of medicated choline transport across the CSF-blood barrier would allow more effective prevention, management and treatment of such disorders. ..
  23. AH RECEPTOR IN NON-MAMMALIAN MODELS
    MARK HAHN; Fiscal Year: 2001
    ..We will determine the diversity and function of AHR genes in fish species commonly used as aquatic models, test the hypothesis that a second AHR-like gene exists in humans, and compare the function of fish and human AHRs. ..
  24. MODULATION OF CHOROID PLEXUS CHOLINE TRANSPORT BY METALS
    Alice Villalobos; Fiscal Year: 2001
    ..abstract_text> ..
  25. STRESS MODULATION OF CHOLINE TRANSPORT BY CHOROID PLEXUS
    Alice Villalobos; Fiscal Year: 2002
    ..Therefore, a greater understanding of the energetics and modulation of medicated choline transport across the CSF-blood barrier would allow more effective prevention, management and treatment of such disorders. ..
  26. The biological activity of metal ion-gastrin complexes
    GRAHAM BALDWIN; Fiscal Year: 2002
    ..In the longer term definition of high affinity receptors for PDP-metal ion complexes may permit the development of novel therapies for treatment of disorders of iron metabolism and of gastrointestinal cancers. ..
  27. MODULATION OF CHOROID PLEXUS CHOLINE TRANSPORT BY METALS
    Alice Villalobos; Fiscal Year: 2002
    ..abstract_text> ..
  28. AHR signaling in Mammalian and Non-Mammalian Models
    MARK HAHN; Fiscal Year: 2003
    ..These studies will provide a better understanding of the possible role of human AHRR in modulating dioxin effects. ..
  29. The biological activity of metal ion-gastrin complexes
    GRAHAM BALDWIN; Fiscal Year: 2003
    ..In the longer term definition of high affinity receptors for PDP-metal ion complexes may permit the development of novel therapies for treatment of disorders of iron metabolism and of gastrointestinal cancers. ..
  30. AHR signaling in Mammalian and Non-Mammalian Models
    MARK HAHN; Fiscal Year: 2004
    ..These studies will provide a better understanding of the possible role of human AHRR in modulating dioxin effects. ..
  31. AHR signaling in Mammalian and Non-Mammalian Models
    Mark E Hahn; Fiscal Year: 2011
    ....