rana catesbeiana

Summary

Summary: A species of the family Ranidae (true frogs). The only anuran properly referred to by the common name "bullfrog", it is the largest native anuran in North America.

Top Publications

  1. doi Collision-sensitive neurons in the optic tectum of the bullfrog, Rana catesbeiana
    Hideki Nakagawa
    Department of Brain Science and Engineering, Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, Fukuoka, Japan
    J Neurophysiol 104:2487-99. 2010
  2. pmc The emerging amphibian pathogen Batrachochytrium dendrobatidis globally infects introduced populations of the North American bullfrog, Rana catesbeiana
    Trenton W J Garner
    Institute of Zoology, Zoological Society of London, Regent s Park, London NW1 4RY, UK
    Biol Lett 2:455-9. 2006
  3. ncbi Input and output characteristics of collision avoidance behavior in the frog Rana catesbeiana
    Keisuke Yamamoto
    Department of Brain Science and Engineering, Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, Kitakyushu, Fukuoka 808 0196, Japan
    Brain Behav Evol 62:201-11. 2003
  4. ncbi Rana catesbeiana virus Z (RCV-Z): a novel pathogenic ranavirus
    Sai Majji
    Department of Microbiology, University of Mississippi Medical Center, Jackson, Mississipi 39216, USA
    Dis Aquat Organ 73:1-11. 2006
  5. pmc Multiple-timescale dynamics underlying spontaneous oscillations of saccular hair bundles
    Yuttana Roongthumskul
    Department of Physics and Astronomy and California NanoSystems Institute, University of California, Los Angeles, California, USA
    Biophys J 101:603-10. 2011
  6. ncbi Elevated maintenance costs in an anuran (Rana catesbeiana) exposed to a mixture of trace elements during the embryonic and early larval periods
    C L Rowe
    University of Georgia, Savannah River Ecology Laboratory, Aiken, South Carolina 29802, USA
    Physiol Zool 71:27-35. 1998
  7. pmc Analysis of the Rana catesbeiana tadpole tail fin proteome and phosphoproteome during T3-induced apoptosis: identification of a novel type I keratin
    Dominik Domanski
    Department of Biochemistry and Microbiology, University of Victoria, PO Box 3055, Victoria, BC V8W 3P6, Canada
    BMC Dev Biol 7:94. 2007
  8. ncbi Genetic evidence for female-biased dispersal in the bullfrog, Rana catesbeiana (Ranidae)
    James D Austin
    dagger Department of Biology, Queen s University, Kingston, Ontario, Canada K7L 3N6
    Mol Ecol 12:3165-72. 2003
  9. ncbi Solution structure of the cytotoxic RNase 4 from oocytes of bullfrog Rana catesbeiana
    Chun Hua Hsu
    Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan, ROC
    J Mol Biol 326:1189-201. 2003
  10. pmc Cell proliferation in the forebrain and midbrain of the adult bullfrog, Rana catesbeiana
    Andrea Megela Simmons
    Department of Psychology, Brown University, Providence, RI 02912, USA
    Brain Behav Evol 71:41-53. 2008

Research Grants

  1. MECHANISMS OF THYROID HORMONE ACTION IN DEVELOPMENT
    VALERIE GALTON; Fiscal Year: 1991
  2. Thyroid hormone action in the developing eye
    Mark Schneider; Fiscal Year: 2002
  3. Thyroid hormone action in the developing eye
    Mark Schneider; Fiscal Year: 2003
  4. Central Respiratory Chemoreception in the Amphibian
    DEBORA ZAMORA; Fiscal Year: 2007
  5. NEUROETHOLOGY OF VOCAL COMMUNICATION
    Andrea Simmons; Fiscal Year: 2006
  6. STRUCTURE AND DIVERSITY IN THE IMMUNE SYSTEM
    Lisa Steiner; Fiscal Year: 1980
  7. SENSORY NEURON ADDITION IN RAT
    PAUL FAREL; Fiscal Year: 2002
  8. Hair-Bundle Lipids
    Peter Gillespie; Fiscal Year: 2009
  9. ROLE OF CALCIUM PUMPING IN HAIR-BUNDLE FUNCTION
    Peter Gillespie; Fiscal Year: 2004
  10. Quantifying Hair Bundle Components
    Peter Gillespie; Fiscal Year: 2007

Detail Information

Publications229 found, 100 shown here

  1. doi Collision-sensitive neurons in the optic tectum of the bullfrog, Rana catesbeiana
    Hideki Nakagawa
    Department of Brain Science and Engineering, Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, Fukuoka, Japan
    J Neurophysiol 104:2487-99. 2010
    ..This strongly suggests that the collision-sensitive neurons of the frog comprise a threshold detector, which triggers collision avoidance behavior...
  2. pmc The emerging amphibian pathogen Batrachochytrium dendrobatidis globally infects introduced populations of the North American bullfrog, Rana catesbeiana
    Trenton W J Garner
    Institute of Zoology, Zoological Society of London, Regent s Park, London NW1 4RY, UK
    Biol Lett 2:455-9. 2006
    ..Here, we show that introduced North American bullfrogs (Rana catesbeiana) consistently carry this emerging pathogenic fungus...
  3. ncbi Input and output characteristics of collision avoidance behavior in the frog Rana catesbeiana
    Keisuke Yamamoto
    Department of Brain Science and Engineering, Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, Kitakyushu, Fukuoka 808 0196, Japan
    Brain Behav Evol 62:201-11. 2003
    ..07, F(2,14) = 0.46 and F(2,14) = 0.70, respectively; at 4 m/s, F(2,15) = 0.50, F(2,14) = 0.68 and F(2,14) = 0.41, respectively, p > 0.05). Thus, frog collision avoidance behavior seems to have an all or none-like property...
  4. ncbi Rana catesbeiana virus Z (RCV-Z): a novel pathogenic ranavirus
    Sai Majji
    Department of Microbiology, University of Mississippi Medical Center, Jackson, Mississipi 39216, USA
    Dis Aquat Organ 73:1-11. 2006
    A virus, designated Rana catesbeiana virus Z (RCV-Z), was isolated from the visceral tissue of moribund tadpoles of the North American bullfrog Rana catesbeiana...
  5. pmc Multiple-timescale dynamics underlying spontaneous oscillations of saccular hair bundles
    Yuttana Roongthumskul
    Department of Physics and Astronomy and California NanoSystems Institute, University of California, Los Angeles, California, USA
    Biophys J 101:603-10. 2011
    ..We use numerical modeling to explore the effects of internal parameters on the oscillatory profiles, and to reproduce the experimental modulation induced by mechanical or ionic manipulation...
  6. ncbi Elevated maintenance costs in an anuran (Rana catesbeiana) exposed to a mixture of trace elements during the embryonic and early larval periods
    C L Rowe
    University of Georgia, Savannah River Ecology Laboratory, Aiken, South Carolina 29802, USA
    Physiol Zool 71:27-35. 1998
    ..maintenance costs (standard metabolic rates, measured as O2 consumption at rest) in tadpoles of the bullfrog, Rana catesbeiana, and exposure to contaminants in a coal ash-polluted habitat (characterized by a variety of trace elements)...
  7. pmc Analysis of the Rana catesbeiana tadpole tail fin proteome and phosphoproteome during T3-induced apoptosis: identification of a novel type I keratin
    Dominik Domanski
    Department of Biochemistry and Microbiology, University of Victoria, PO Box 3055, Victoria, BC V8W 3P6, Canada
    BMC Dev Biol 7:94. 2007
    ..This process has been intensively studied at the genomic level yet very little information at the proteomic level exists. In addition, there is increasing evidence that changes in the phosphoproteome influence TH action...
  8. ncbi Genetic evidence for female-biased dispersal in the bullfrog, Rana catesbeiana (Ranidae)
    James D Austin
    dagger Department of Biology, Queen s University, Kingston, Ontario, Canada K7L 3N6
    Mol Ecol 12:3165-72. 2003
    ..We predicted female-biased dispersal in the bullfrog (Rana catesbeiana) based on aspects of their mating system and tested this prediction using data from seven polymorphic DNA ..
  9. ncbi Solution structure of the cytotoxic RNase 4 from oocytes of bullfrog Rana catesbeiana
    Chun Hua Hsu
    Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan, ROC
    J Mol Biol 326:1189-201. 2003
    ..residues linked with four disulfide bridges, is a cytotoxic ribonuclease isolated from oocytes of bullfrog Rana catesbeiana. RNase 4 belongs to the bovine pancreatic ribonuclease (RNase A) superfamily...
  10. pmc Cell proliferation in the forebrain and midbrain of the adult bullfrog, Rana catesbeiana
    Andrea Megela Simmons
    Department of Psychology, Brown University, Providence, RI 02912, USA
    Brain Behav Evol 71:41-53. 2008
    The distribution of proliferating cells in the midbrain, thalamus, and telencephalon of adult bullfrogs (Rana catesbeiana) was examined using immunohistochemistry for the thymidine analog 5-bromo-2'-deoxyuridine (BrdU) and DNA dot-..
  11. doi Characterization of plasma triiodophenol binding proteins in vertebrates and tissue distribution of triiodophenol in Rana catesbeiana tadpoles
    Kiyoshi Yamauchi
    Department of Biological Science, Faculty of Science, Shizuoka University, Shizuoka 422 8529, Japan
    Comp Biochem Physiol C Toxicol Pharmacol 153:328-35. 2011
    ..thyroid hormone disrupting chemical, with serum proteins from rainbow trout (Onchorhynchus mykiss), bullfrog (Rana catesbeiana), chicken (Gallus gallus), pig (Sus scrofa domesticus), and rat (Rattus norvegicus) using a [(125)I]TIP ..
  12. pmc Comparison of a hair bundle's spontaneous oscillations with its response to mechanical stimulation reveals the underlying active process
    P Martin
    Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021-6399, USA
    Proc Natl Acad Sci U S A 98:14380-5. 2001
    ..This behavior, which is not generic for active oscillators, can be accommodated by a simple model that characterizes quantitatively the fluctuations of the spontaneous movements as well as the hair bundle's linear response function...
  13. ncbi Acute neurosteroid modulation and subunit isolation of the gamma-aminobutyric acidA receptor in the bullfrog, Rana catesbeiana
    D M Hollis
    Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana 46556, USA
    J Mol Endocrinol 32:921-34. 2004
    ..Thus, neurosteroid modulation of the GABA(A) receptor was investigated in the brain of the bullfrog (Rana catesbeiana) using the mammalian GABA(A) receptor agonist [(3)H]muscimol...
  14. ncbi Regulation of the respiratory central pattern generator by chloride-dependent inhibition during development in the bullfrog (Rana catesbeiana)
    Lise Broch
    Department of Biological Sciences, California State University Hayward, Hayward, CA 94542, USA
    J Exp Biol 205:1161-9. 2002
    Isolated brainstem preparations from larval (tadpole) and adult Rana catesbeiana were used to examine inhibitory mechanisms for developmental regulation of the respiratory central pattern generator (CPG)...
  15. ncbi Distribution of GABA-like immunoreactive cell bodies in the brains of two amphibians, Rana catesbeiana and Xenopus laevis
    David M Hollis
    Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA
    Brain Behav Evol 65:127-42. 2005
    ..We thus used immunocytochemistry to locate putative GABAergic cells in the brains of male bullfrogs (Rana catesbeiana) and South African clawed frogs (Xenopus laevis)...
  16. ncbi Genistein prevents thyroid hormone-dependent tail regression of Rana catesbeiana tadpoles by targetting protein kinase C and thyroid hormone receptor alpha
    L Ji
    Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada
    Dev Dyn 236:777-90. 2007
    ..soy products and tyrosine kinase inhibitor) and the PKC inhibitor (H7) prevent T(3)-induced regression of the Rana catesbeiana tadpole tail...
  17. ncbi Structural characteristics of bullfrog (Rana catesbeiana) transthyretin and its cDNA--comparison of its pattern of expression during metamorphosis with that of lipocalin
    K Yamauchi
    Department of Biology, Faculty of Science, Shizuoka University, Japan
    Eur J Biochem 256:287-96. 1998
    ..Here, we report the nucleotide sequence of the cDNA for a THBP found in plasma of bullfrog (Rana catesbeiana) tadpoles before the climax of metamorphosis...
  18. doi Ultra high dilution of triiodothyronine modifies cellular apoptosis in Rana catesbeiana tadpole tail in vitro
    J R P Guedes
    Laboratory of Molecular Pathology, Department of Pathology, University of Sao Paulo School of Medicine, Av Dr Arnaldo 455, Sao Paulo, SP, Brazil
    Homeopathy 100:220-7. 2011
    ..Ultra High Dilutions (UHD) are diluted beyond the Avogadro limit with dynamization (dilution with succussion). The process of anuran amphibian metamorphosis is controlled by thyroid hormones, including the resorption of the tadpole tail...
  19. pmc Distribution of frequencies of spontaneous oscillations in hair cells of the bullfrog sacculus
    D Ramunno-Johnson
    Department of Physics and Astronomy and California Nanosytems Institute University of California, Los Angeles, California 90095, USA
    Biophys J 96:1159-68. 2009
    Under in vitro conditions, free-standing hair bundles of the bullfrog (Rana catesbeiana) sacculus have exhibited spontaneous oscillations...
  20. doi Dynamic state and evoked motility in coupled hair bundles of the bullfrog sacculus
    C E Strimbu
    University of California, Los Angeles Department of Physics and Astronomy and the California NanoSystems Institute, 475 Portola Plaza, Los Angeles, CA 90095, USA
    Hear Res 265:38-45. 2010
    ..In both of these systems, hair bundle motion phase-locked by the electrical signal was found to induce movement in the overlying structures...
  21. ncbi Caspase activation in response to cytotoxic Rana catesbeiana ribonuclease in MCF-7 cells
    C C Hu
    Institute of Biology and Anatomy, National Defense Medical Center, 161, Sec. 6, MinChuan E. Rd, 114, Taipei, Taiwan
    FEBS Lett 503:65-8. 2001
    b>Rana catesbeiana ribonuclease (RC-RNase) and onconase were proven to own anti-tumor activity...
  22. doi Characterization of iodothyronine sulfotransferase activity in the cytosol of Rana catesbeiana tadpole tissues
    Farhana Babli Rahman
    Graduate School of Science and Engineering, Shizuoka University, Shizuoka 422 8529, Japan
    Gen Comp Endocrinol 166:396-403. 2010
    We have investigated the sulfation of thyroid hormones (THs) in the cytosol from Rana catesbeiana tadpole tissues...
  23. ncbi Micronucleus test for monitoring genotoxicity of polluted river water in Rana catesbeiana tadpoles
    M V M A Wirz
    Laboratory of Experimental Air Pollution, School of Medicine, University of Sao Paulo USP, Av Dr Arnaldo 455, CEP 12046 903 São Paulo, SP, Brazil
    Bull Environ Contam Toxicol 75:1220-7. 2005
  24. doi Correlated movement of hair bundles coupled to the otolithic membrane in the bullfrog sacculus
    C E Strimbu
    University of California, Los Angeles Department of Physics and Astronomy, Los Angeles, CA 90095, USA
    Hear Res 256:58-63. 2009
    ..We imaged significant portions of the saccular epithelium, up to 40 x 350 microm(2), and observed a high degree of correlation over those scales...
  25. pmc Effect of low dose exposure to the herbicide atrazine and its metabolite on cytochrome P450 aromatase and steroidogenic factor-1 mRNA levels in the brain of premetamorphic bullfrog tadpoles (Rana catesbeiana)
    Mark P Gunderson
    Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada
    Aquat Toxicol 102:31-8. 2011
    ..In the present study, we cloned and characterized partial sequences for bullfrog (Rana catesbeiana) SF-1 and CYP19 and examined the effects of a 48h exposure to 1 and 100μg/l of the herbicide atrazine (ATZ) ..
  26. pmc Representation of waveform periodicity in the auditory midbrain of the bullfrog, Rana catesbeiana
    A M Simmons
    Departments of Psychology and Neuroscience, Brown University, Box 1853, Providence, RI 02912, USA
    J Assoc Res Otolaryngol 1:2-24. 2000
    ..They further show that a populationbased analysis can increase the precision with which temporal features are represented in the central auditory system...
  27. pmc High-resolution structure of hair-cell tip links
    B Kachar
    Section on Structural Cell Biology, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD 20892 4163, USA
    Proc Natl Acad Sci U S A 97:13336-41. 2000
    ..Such behavior is incompatible with the measured elasticity of the gating spring, suggesting that the gating spring instead lies in series with the helical segment of the tip link...
  28. ncbi Plasma membrane Ca2+-ATPase extrudes Ca2+ from hair cell stereocilia
    E N Yamoah
    Department of Physiology, The Johns Hopkins University, Baltimore, Maryland 21205, USA
    J Neurosci 18:610-24. 1998
    ..Our data further indicate that PMCA could elevate the extracellular Ca2+ concentration close to hair bundles above the low level found in bulk endolymph...
  29. ncbi Nerve conduction block utilising high-frequency alternating current
    K L Kilgore
    MetroHealth Medical Center, Cleveland, Ohio, USA
    Med Biol Eng Comput 42:394-406. 2004
    ..The results of this study demonstrated that high-frequency AC can be used to produce a fast-acting, and quickly reversible nerve conduction block that may have multiple applications in the treatment of unwanted neural activity...
  30. pmc Compressive nonlinearity in the hair bundle's active response to mechanical stimulation
    P Martin
    Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021-6399, USA
    Proc Natl Acad Sci U S A 98:14386-91. 2001
    ..This scaling behavior, also found in the response of the mammalian basilar membrane to sound, signals the operation of an amplificatory process at the brink of an oscillatory instability, a Hopf bifurcation...
  31. ncbi Why islands are easier to invade: human influences on bullfrog invasion in the Zhoushan archipelago and neighboring mainland China
    Li Yiming
    Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, 25 Beisihuanxi Road, Haidian, 100080, Beijing, China
    Oecologia 148:129-36. 2006
    ..We compared invasion success (the probability of establishing a wild reproducing population) for bullfrogs (Rana catesbeiana) introduced to enclosures on 26 farms on islands in the Zhoushan archipelago and 15 farms in neighboring ..
  32. pmc Hair-bundle movements elicited by transepithelial electrical stimulation of hair cells in the sacculus of the bullfrog
    D Bozovic
    The Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 100:958-63. 2003
    ..A model for electrically driven bundle motion that incorporates the negative stiffness of the hair bundle as well as its two mechanisms of motility captures the essential features of the measured responses...
  33. pmc Transfer characteristics of the hair cell's afferent synapse
    Erica C Keen
    Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021 6399, USA
    Proc Natl Acad Sci U S A 103:5537-42. 2006
    ..This result implies that, for receptor potentials in the physiological range, the hair cell's synapse transmits information with high fidelity...
  34. ncbi Mechanical leverage in the middle ear of the American bullfrog, Rana catesbeiana
    Yehudah L Werner
    Department of Psychology, Princeton University, Princeton, NJ 08544, USA
    Hear Res 175:54-65. 2003
    ..But dissection of Rana catesbeiana ears showed: the extracolumella, as long as the columella, is proximally expanded in the vertical plane, ..
  35. ncbi THE effects of tonic lung inflation on ventilation in the American bullfrog Rana catesbeiana Shaw
    C E Sanders
    Department of Zoology, University of British Columbia, 6270 University Boulevard, Vancouver, British Columbia, V6T 1Z4, Canada
    J Exp Biol 204:2647-56. 2001
    ....
  36. ncbi Avoidance response of juvenile Pacific treefrogs to chemical cues of introduced predatory bullfrogs
    D P Chivers
    Department of Biology, University of Saskatchewan, Saskatoon
    J Chem Ecol 27:1667-76. 2001
    Bullfrogs (Rana catesbeiana), native to eastern North America, were introduced into Oregon in the 1930's. Bullfrogs are highly efficient predators that are known to eat a variety of prey including other amphibians...
  37. ncbi Survival of bundleless hair cells and subsequent bundle replacement in the bullfrog's saccule
    Jonathan E Gale
    Department of Otolaryngology, HNS, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA
    J Neurobiol 50:81-92. 2002
    ..The results indicate that sensory hair cells can undergo intracellular self-repair in the absence of mitosis, offering new possibilities for functional hair cell recovery and an explanation for non-proliferative recovery...
  38. ncbi Coding of amplitude modulation in the auditory midbrain of the bullfrog (Rana catesbeiana) across metamorphosis
    S S Boatright Horowitz
    Department of Neuroscience, Brown University, Providence, RI 02912, USA
    J Comp Physiol A 184:219-31. 1999
    ..These data suggest that different neural codes for processing of the periodicity of complex signals operate in early stage tadpoles than in postmetamorphic froglets...
  39. ncbi Developmental changes in central O2 chemoreflex in Rana catesbeiana: the role of noradrenergic modulation
    Stéphanie Fournier
    Department of Pediatrics, Universite Laval, Centre de Recherche du Centre Hospitalier Universitaire de Québec, Quebec City, QC, Canada
    J Exp Biol 210:3015-26. 2007
    The in vitro brainstem preparation from Rana catesbeiana shows a functional central O(2) chemoreflex. Acute brainstem exposure to hypoxic superfusate elicits lung burst frequency responses that change over the course of development...
  40. pmc Aquaculture enclosures relate to the establishment of feral populations of introduced species
    Xuan Liu
    Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Chaoyang, Beijing, China
    PLoS ONE 4:e6199. 2009
    ..Our findings are the first to quantify the importance of improving farming enclosures to control and minimize the risk from introduced species...
  41. pmc Mass mortality associated with a frog virus 3-like Ranavirus infection in farmed tadpoles Rana catesbeiana from Brazil
    Rolando Mazzoni
    Instituto de Investigaciones Pesqueras, Facultad de Veterinaria, Universidad de la Republica, Montevideo, Uruguay
    Dis Aquat Organ 86:181-91. 2009
    ..been recently associated with mass mortality events in Brazilian farmed tadpoles of the American bullfrog Rana catesbeiana Shaw, 1802. The objectives of the present study were to further characterize the virus isolated from sick R...
  42. ncbi Development of the respiratory response to hypoxia in the isolated brainstem of the bullfrog Rana catesbeiana
    Rachel E Winmill
    Department of Biological Sciences, California State University, Hayward, Hayward, CA 94542, USA
    J Exp Biol 208:213-22. 2005
    ..We hypothesize that the cessation of respiratory activity in post-metamorphic tadpoles and adults is an adaptive, energy-saving response to low oxygen...
  43. ncbi Oxygen sensitive chemoreceptors in the first gill arch of the tadpole, Rana catesbeiana
    C Straus
    Department of Medical Physiology, Faculty of Medicine, University of Calgary, AB, Canada
    Can J Physiol Pharmacol 79:959-62. 2001
    Spike frequency was recorded in the nerve of the isolated superfused first gill arch of the bullfrog larva, Rana catesbeiana and the response to different superfusate PO2 was evaluated...
  44. doi NMR and biophysical elucidation of structural effects on extra N-terminal methionine residue of recombinant amphibian RNases from Rana catesbeiana
    Chun Hua Hsu
    Department of Agricultural Chemistry, National Taiwan University, Taipei 106, Taiwan
    J Biochem 148:209-15. 2010
    ..NMR techniques, and the results were compared with those of their authentic RNases extracted from oocytes of Rana catesbeiana. Although the overall structures of the recombinant and authentic proteins are almost identical, the extra N-..
  45. pmc Hair bundles are specialized for ATP delivery via creatine kinase
    Jung Bum Shin
    Oregon Hearing Research Center and Vollum Institute, Oregon Health and Science University, Portland, OR 97239, USA
    Neuron 53:371-86. 2007
    ..Consistent with this critical role in hair bundle function, the creatine kinase circuit is essential for high-sensitivity hearing as demonstrated by hearing loss in creatine kinase knockout mice...
  46. pmc Ca2+ changes the force sensitivity of the hair-cell transduction channel
    Eunice L M Cheung
    Department of Engineering and Applied Science, Harvard University, Cambridge, Massachusetts, USA
    Biophys J 90:124-39. 2006
    ..In addition, we characterized a faster, voltage-dependent "flick", which requires intact tip links but not current through transduction channels...
  47. pmc The unitary event underlying multiquantal EPSCs at a hair cell's ribbon synapse
    Geng Lin Li
    The Vollum Institute, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Neurosci 29:7558-68. 2009
    ..We propose that the large EPSCs reflect the highly synchronized release of multiple vesicles at single presynaptic ribbon-type active zones through a compound or coordinated vesicle fusion mechanism...
  48. pmc Parvalbumin 3 is an abundant Ca2+ buffer in hair cells
    Stefan Heller
    Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10021, USA
    J Assoc Res Otolaryngol 3:488-98. 2002
    ..Parvalbumin 3 is therefore a significant mobile Ca2+ buffer, and perhaps the dominant buffer, in many types of hair cell. Moreover, parvalbumin 3 provides an early marker for developing hair cells in the frog, chicken, and zebrafish...
  49. pmc Multiple modes of calcium-induced calcium release in sympathetic neurons II: a [Ca2+](i)- and location-dependent transition from endoplasmic reticulum Ca accumulation to net Ca release
    J Hongpaisan
    Laboratory of Neurobiology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    J Gen Physiol 118:101-12. 2001
    ....
  50. ncbi Plasma membrane Ca2+-ATPase isoform 2a is the PMCA of hair bundles
    R A Dumont
    Department of Physiology, Johns Hopkins University, Baltimore, Maryland 21205, USA
    J Neurosci 21:5066-78. 2001
    ..Because PMCA2a is the only Ca(2+) pump present at appreciable levels in hair bundles, the biochemical properties of this pump must account fully for the physiological features of transmembrane Ca(2+) pumping in bundles...
  51. ncbi Rapid diversification of RNase A superfamily ribonucleases from the bullfrog, Rana catesbeiana
    H F Rosenberg
    Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Mol Evol 53:31-8. 2001
    We present sequences of five novel RNase A superfamily ribonuclease genes of the bullfrog, Rana catesbeiana. All five genes encode ribonucleases that are similar to Onconase, a cytotoxic ribonuclease isolated from oocytes of R. pipiens...
  52. ncbi Lineage of anuran epidermal basal cells and their differentiation potential in relation to metamorphic skin remodeling
    Ken ichi Suzuki
    Developmental Biology Laboratory, Department of Biological Science, Graduate School of Science, Hiroshima University, 1 3 1 Kagamiyama, Higashihiroshima 739 8526, Japan
    Dev Growth Differ 44:225-38. 2002
    ..In this culture, larval basal cells differentiated into adult basal cells that reconstituted the adult epidermis. Thus, it was concluded that larval basal cells are the direct progenitor cells of the adult epidermal stem cells...
  53. ncbi Ryanodine receptor isoforms of non-Mammalian skeletal muscle
    Yasuo Ogawa
    Department of Pharmacology, Juntendo University, Tokyo, Japan
    Front Biosci 7:d1184-94. 2002
    ..Taking these findings into consideration, we conclude that CICR is too slow to explain the physiological Ca2+ release on depolarization...
  54. ncbi Vibrometric studies of the middle ear of the bullfrog Rana catesbeiana I. The extrastapes
    Matthew J Mason
    Department of Physiological Science, UCLA, 405 Hilgard Avenue, Los Angeles, CA 90095, USA
    J Exp Biol 205:3153-65. 2002
    ..was used to measure the vibration velocity at different points on the ossicular apparatus of the bullfrog Rana catesbeiana in response to free-field sound...
  55. ncbi Symbiotic fermentation, digesta passage, and gastrointestinal morphology in bullfrog tadpoles (Rana catesbeiana)
    Gregory S Pryor
    Department of Zoology, University of Florida, Gainesville, 32611 8525, USA
    Physiol Biochem Zool 78:201-15. 2005
    ..to compare gut structure and inhabitants, digesta passage, and microbial fermentation in bullfrog tadpoles (Rana catesbeiana) to those in other herbivores...
  56. ncbi Detection of environmental endocrine-disruptor effects on gene expression in live Rana catesbeiana tadpoles using a tail fin biopsy technique
    N Veldhoen
    Department of Biochemistry and Microbiology, University of Victoria, British Columbia, Canada
    Environ Toxicol Chem 20:2704-8. 2001
    We describe a novel method of rapidly assessing exposure of premetamorphic Rana catesbeiana tadpoles to endocrine-disrupting chemicals...
  57. ncbi Vibrometric studies of the middle ear of the bullfrog Rana catesbeiana II. The operculum
    Matthew J Mason
    Department of Physiological Science, UCLA, 405 Hilgard Avenue, Los Angeles, CA 90095, USA
    J Exp Biol 205:3167-76. 2002
    ..An alternative or additional role for the opercularis system is proposed, involving the protection of the inner ear from high-amplitude displacements of the stapes footplate during breathing and vocalisation...
  58. pmc Differential regulation of ER Ca2+ uptake and release rates accounts for multiple modes of Ca2+-induced Ca2+ release
    Meredith A Albrecht
    Department of Neurosciences, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA
    J Gen Physiol 119:211-33. 2002
    ....
  59. ncbi Novel Rana keratin genes and their expression during larval to adult epidermal conversion in bullfrog tadpoles
    K Suzuki
    Department of Biological Science, Graduate School of Science, Hiroshima University, Higashihiroshima, Japan
    Differentiation 68:44-54. 2001
    The conversion of the larval to adult epidermis during metamorphosis of tadpoles of bullfrog, Rana catesbeiana, was investigated utilizing newly cloned Rana keratin cDNAs as probes...
  60. pmc Controlling for the effects of history and nonequilibrium conditions in gene flow estimates in northern bullfrog (Rana catesbeiana) populations
    James D Austin
    Department of Biology, Queen s University, Kingston, Ontario, Canada, K7L 3N6
    Genetics 168:1491-506. 2004
    ..We determined the scale at which gene flow can be estimated among breeding aggregations of bullfrogs (Rana catesbeiana) at the northern limit of their range in Ontario, Canada, using seven highly polymorphic DNA microsatellite ..
  61. ncbi Myosin-1c interacts with hair-cell receptors through its calmodulin-binding IQ domains
    Janet L Cyr
    Oregon Hearing Research Center and Vollum Institute, Oregon Health and Science University, Portland, Oregon 97201, USA
    J Neurosci 22:2487-95. 2002
    ..The calcium-sensitive binding of calmodulin to myosin-1c may therefore modulate the interaction of the adaptation motor with other components of the transduction apparatus...
  62. pmc Solitary hair cells are distributed throughout the extramacular epithelium in the bullfrog's saccule
    J E Gale
    Department of Otolaryngology HNS, University of Virginia School of Medicine, Charlottesville 22908, USA
    J Assoc Res Otolaryngol 1:172-82. 2000
    ..It is also possible that they may be produced from cell divisions in the extramacular epithelium that has not been considered capable of giving rise to hair cells...
  63. pmc Multiple modes of calcium-induced calcium release in sympathetic neurons I: attenuation of endoplasmic reticulum Ca2+ accumulation at low [Ca2+](i) during weak depolarization
    M A Albrecht
    Department of Neuroscience, Case Western Reserve University, Cleveland, OH 44106, USA
    J Gen Physiol 118:83-100. 2001
    ..These results emphasize the importance of the relative rates of Ca2+ uptake and release in defining ER contributions to depolarization-induced Ca2+ signals...
  64. ncbi Induction of differentiation rescues HL-60 cells from Rana catesbeiana ribonuclease-induced cell death
    Chyou Wei Wei
    Graduate Institute of Life Sciences, National Defense Medical Center, 114, Taipei, Taiwan
    FEBS Lett 531:421-6. 2002
    b>Rana catesbeiana ribonuclease (RC-RNase) exerted strong anti-tumor activity and its cytotoxicity was shown to correlate with differentiation stages of three different hepatoma cell lines...
  65. ncbi Thyroid hormone response element-like sequence in anuran matrix metalloproteinase 1 gene is responsive to in vivo thyroid hormone administration
    T Sawada
    Department of Biological Science, Graduate School of Science, Hiroshima University, Kagamiyama, Higashihiroshima, Hiroshima 739-8526, Japan
    J Endocrinol 169:477-86. 2001
    Gene (Rmmp1) of matrix metalloproteinase 1 (MMP1) of the bullfrog, Rana catesbeiana, has been shown previously to contain a thyroid hormone response element (TRE)-like sequence in its 5'-upstream region...
  66. ncbi The bactericidal agent triclosan modulates thyroid hormone-associated gene expression and disrupts postembryonic anuran development
    Nik Veldhoen
    Department of Biochemistry and Microbiology, P O Box 3055, STN CSC, University of Victoria, Victoria, British Columbia V8W 3P6, Canada
    Aquat Toxicol 80:217-27. 2006
    ..induces changes in the thyroid hormone-mediated process of metamorphosis of the North American bullfrog, Rana catesbeiana and alters the expression profile of thyroid hormone receptor (TR) alpha and beta, basic transcription ..
  67. ncbi Decreased cyclin-dependent kinase activity promotes thyroid hormone-dependent tail regression in Rana catesbeiana
    Rachel C Skirrow
    Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, Canada
    Cell Tissue Res 328:281-9. 2007
    ..Coincubation with PD098059, a MAPK inhibitor, has no effect. Thus, T(3)-dependent tail regression does not require MAPKs, but a decrease in Cdk2 activity promotes tail regression...
  68. ncbi Molecular cloning and functional expression of a skeletal muscle dihydropyridine receptor from Rana catesbeiana
    J Zhou
    Department of Molecular Biophysics and Physiology, Rush University, Chicago, Illinois 60612, USA
    J Biol Chem 273:25503-9. 1998
    ..and Tanabe, T. (1997) J. Gen. Physiol. 110, 379-389). This molecule constitutes a new tool for studies of excitation-contraction coupling, gating, modulation, and gene expression...
  69. ncbi Activation patterns and length changes in hindlimb muscles of the bullfrog Rana catesbeiana during jumping
    J M Olson
    Department of Biology, Villanova University, Villanova, PA 19085, USA and Biology Department, Northeastern University, Boston, MA 02115, USA
    J Exp Biol 201:2763-77. 1998
    We measured the electromyographic (EMG) activity of seven hindlimb muscles during jumping in the bullfrog Rana catesbeiana. The semimembranosus, gracilis major, gluteus magnus, adductor magnus, cruralis and plantaris longus were ..
  70. pmc Spontaneous oscillation by hair bundles of the bullfrog's sacculus
    Pascal Martin
    Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, New York 10021 6399, USA
    J Neurosci 23:4533-48. 2003
    ..These observations accord with a model in which oscillations arise from the interplay of the hair bundle's negative stiffness with the activity of adaptation motors and with Ca 2+-dependent relaxation of gating springs...
  71. pmc Onset of feedback reactions underlying vertebrate rod photoreceptor light adaptation
    P D Calvert
    Howe Laboratory of Ophthalmology, Harvard Medical School and the Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    J Gen Physiol 111:39-51. 1998
    ..Therefore, cGMP-dependent regulation of transducin GTPase is likely to occur only during prolonged bright illumination...
  72. pmc Differential effects of voltage-dependent inactivation and local anesthetics on kinetic phases of Ca2+ release in frog skeletal muscle
    Gustavo Brum
    Departamento de Biofisica, Facultad de Medicina, Montevideo, Uruguay
    Biophys J 85:245-54. 2003
    ....
  73. pmc Emerging pathogen of wild amphibians in frogs (Rana catesbeiana) farmed for international trade
    Rolando Mazzoni
    Instituto de Investigaciones Pesqueras, Montevideo, Uruguay
    Emerg Infect Dis 9:995-8. 2003
    ..We report the causative agent, Batrachochytrium dendrobatidis, in North American bullfrogs (Rana catesbeiana) farmed for the international restaurant trade...
  74. ncbi Biomechanics of vibration reception in the bullfrog, Rana catesbeiana
    T E Hetherington
    Department of Zoology, Ohio State University, Columbus 43210 1293
    J Comp Physiol A 163:43-52. 1988
    ..The role of the OPS in reception of vibrations was examined in bullfrogs (Rana catesbeiana) tested in various postures that manipulated differential motion between the shoulder girdle (the origin of ..
  75. pmc Unifying the various incarnations of active hair-bundle motility by the vertebrate hair cell
    Jean Yves Tinevez
    Laboratoire Physico Chimie Curie, CNRS, Institut Curie, Paris, France
    Biophys J 93:4053-67. 2007
    ....
  76. ncbi Molecular identification of the skin transformation center of anuran larval skin using genes of Rana adult keratin (RAK) and SPARC as probes
    Yuji Ishida
    Laboratory of Developmental Biology, Department of Biological Science, Graduate School of Science, Hiroshima University, 1 3 1, Kagamiyama, Higashihiroshima, 739 8526, Japan
    Dev Growth Differ 45:515-26. 2003
    ..This suggestion was tested by investigating the effect of SPARC on cultured larval basal cells. We observed that SPARC suppressed the expression of rak, but not rlk...
  77. ncbi Recoverin has S-modulin activity in frog rods
    S Kawamura
    Department of Physiology, Keio University School of Medicine, Tokyo, Japan
    J Biol Chem 268:14579-82. 1993
    ..Here, we show that recoverin has similar activity as S-modulin, and the amino acid sequences of both proteins are similar. The results strongly suggest that recoverin is bovine S-modulin and regulates PDE activation...
  78. ncbi Frog p26olf, a molecule with two S100-like regions in a single peptide
    Naofumi Miwa
    Department of Biology, Graduate School of Science, Osaka University, Osaka 560 0043, Japan
    Microsc Res Tech 60:593-9. 2003
    An S100-like calcium-binding protein, p26olf, was originally isolated from the frog (Rana Catesbeiana) olfactory epithelium with four chromatographical steps...
  79. pmc Apoptosis during the seasonal spermatogenic cycle of Rana catesbeiana
    Estela Sasso-Cerri
    Department of Morphology, Dental School, Sao Paulo State University UNESP, Araraquara, Brazil
    J Anat 209:21-9. 2006
    In the bullfrog Rana catesbeiana, testicular weight is constant throughout the year, but the volume densities of germinative and interstitial compartments undergo inverse changes from winter (non-breeding) to summer (breeding)...
  80. ncbi Mechanics of the inner ear of the bullfrog (Rana catesbeiana): the contact membranes and the periotic canal
    A P Purgue
    Department of Physiological Science, UCLA, Los Angeles, CA 90095 1606, USA
    J Comp Physiol A 186:481-8. 2000
    ..morphological measurements of the periotic canal based on internal casts of the inner ear in the bullfrog (Rana catesbeiana) revealed that it is divided into a wide, tapered section and a narrower section comprised of two branches ..
  81. ncbi A model for energy flow in the inner ear of the bullfrog (Rana catesbeiana)
    A P Purgue
    Department of Physiological Science, UCLA, Los Angeles, CA 90095 1606, USA
    J Comp Physiol A 186:489-95. 2000
    ..Our model explains the main features of the empirical data obtained from direct measurement of the amphibian papilla and basilar papilla contact membranes reported in an accompanying paper (this issue)...
  82. ncbi Characterization of the binding of [3H]CGP54626 to GABAB receptors in the male bullfrog (Rana catesbeiana)
    Matthew J Asay
    Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA
    Brain Res 1094:76-85. 2006
    ..to determine the pharmacology of putative receptors in the brain of an anuran amphibian, the male bullfrog (Rana catesbeiana)...
  83. ncbi Residues involved in the catalysis, base specificity, and cytotoxicity of ribonuclease from Rana catesbeiana based upon mutagenesis and X-ray crystallography
    Ying Jen Leu
    Institute of Biomedical Sciences and the Institute of Molecular Biology, Academia Sinica, Taipei 115, and the Department of Life Science, National Tsing Hua University, Hsin Chu 300, Taiwan
    J Biol Chem 278:7300-9. 2003
    The Rana catesbeiana (bullfrog) ribonucleases, which belong to the RNase A superfamily, exert cytotoxicity toward tumor cells...
  84. ncbi Selectively suppressed Ca2+-induced Ca2+ release activity of alpha-ryanodine receptor (alpha-RyR) in frog skeletal muscle sarcoplasmic reticulum: potential distinct modes in Ca2+ release between alpha- and beta-RyR
    T Murayama
    Department of Pharmacology, Juntendo University School of Medicine, Tokyo 113-8421, Japan
    J Biol Chem 276:2953-60. 2001
    ..These results suggest that alpha-RyR in the SR may serve Ca(2+) release in a mode other than CICR, being selectively suppressed in CICR...
  85. ncbi Relationship between steroidogenesis and spermiation in Rana catesbeiana and Leptodactylus ocellatus
    Cinthia Rosemblit
    Laboratorio de Endocrinología Comparada and PRHOM CONICET, Departamento de Biodiversidad y Biologia Experimental, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina
    J Comp Physiol B 176:559-66. 2006
    ..system to analyse the role of steroid hormones in hCG-induced spermiation in two species of anuran amphibian: Rana catesbeiana and Leptodactylus ocellatus...
  86. ncbi Respiratory pattern formation in the isolated bullfrog (Rana catesbeiana) brainstem-spinal cord
    S G Reid
    Department of Zoology, University of British Columbia, Vancouver, Canada
    Respir Physiol 114:239-55. 1998
    ..V, VII, X, and XII of in vitro, saline-perfused, brainstem-spinal cord preparations of the American bullfrog (Rana catesbeiana). Motor output indicative of fictive breathing was present in all preparations...
  87. ncbi Localization of orexin-A-like immunoreactivity in prolactin cells in the bullfrog (Rana catesbeiana) pituitary
    Toshiharu Yamamoto
    Department of Biology, Kanagawa Dental College, Inaoka cho 82, Yokosuka, Kanagawa 238 8580, Japan
    Gen Comp Endocrinol 135:186-92. 2004
    ..techniques were employed to investigate the distribution of orexin-A-like immunoreactivity in the bullfrog (Rana catesbeiana) pituitary. Orexin-A-immunoreactive cells were scattered throughout the pars distalis...
  88. pmc Calcium site specificity. Early Ca2+-related tight junction events
    F Lacaz-Vieira
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, 05508 900 Sao Paulo, Brazil
    J Gen Physiol 110:727-40. 1997
    ....
  89. ncbi Identification of immunoreactive plasma and stomach ghrelin, and expression of stomach ghrelin mRNA in the bullfrog, Rana catesbeiana
    Hiroyuki Kaiya
    Department of Biochemistry, National Cardiovascular Center Research Institute, 5 7 1 Fujishirodai, Suita, Osaka 565 8565, Japan
    Gen Comp Endocrinol 148:236-44. 2006
    In this study, we established a radioimmunoassay (RIA) specific for ghrelin from the bullfrog Rana catesbeiana using a novel antibody raised against the C-terminal amino acid sequence of bullfrog ghrelin [13-28]...
  90. ncbi Habituation and sensitization of aggression in bullfrogs (Rana catesbeiana): testing the dual-process theory of habituation
    M A Bee
    Division of Biological Sciences, University of Missouri-Columbia, USA
    J Comp Psychol 115:307-16. 2001
    The aggressive response of male bullfrogs (Rana catesbeiana) habituates with repeated broadcasts of acoustic stimuli simulating a new territorial neighbor...
  91. ncbi cGMP suppresses GTPase activity of a portion of transducin equimolar to phosphodiesterase in frog rod outer segments. Light-induced cGMP decreases as a putative feedback mechanism of the photoresponse
    - Arshavsky VYu
    Laboratory of Molecular Biology, University of Wisconsin, Madison 53706
    J Biol Chem 266:18530-7. 1991
    ....
  92. ncbi Thyroid hormones regulate the frequency of miniature end-plate currents in pre- and prometamorphic stages of the tadpole tail
    Legier V Rojas
    Department of Physiology, School of Medicine, Universidad Central del Caribe, and Center for Molecular and Behavioral Neuroscience, Bayamon, Puerto Rico
    J Neurosci Res 71:670-8. 2003
    ..The present study demonstrated that T(3) induces a remarkable nongenomic action in the NMJ of the tadpole tail at pre- and promatamorphic stages...
  93. ncbi Central CO2 chemoreception in developing bullfrogs: anomalous response to acetazolamide
    Barbara E Taylor
    Department of Physiology, Dartmouth Medical School, Lebanon, New Hampshire 03756 0001, USA
    J Appl Physiol (1985) 94:1204-12. 2003
    Central CO(2) chemoreception and the role of carbonic anhydrase were assessed in brain stems from Rana catesbeiana tadpoles and frogs...
  94. ncbi Analysis of slow hyperpolarizing potentials in frog taste cells induced by glossopharyngeal nerve stimulation
    Toshihide Sato
    Division of Integrative Sensory Physiology, Nagasaki University Graduate School of Biomedical Sciences, 1 7 1 Sakamoto, Nagasaki 852 8588, Japan
    Chem Senses 29:651-7. 2004
    ..These results suggest that the slow HPs are generated by closing the nonselective cation channels in the postsynaptic membrane of taste cells following possible release of substance P from the GP nerve terminals in the taste disk...
  95. pmc Slowed N-type calcium channel (CaV2.2) deactivation by the cyclin-dependent kinase inhibitor roscovitine
    Zafir Buraei
    Department of Physiology, Tulane University Health Sciences Center, New Orleans, Louisiana, USA
    Biophys J 89:1681-91. 2005
    ..A model where roscovitine reduced a backward rate constant between two open states was able to reproduce the effect of roscovitine on both activation and deactivation...
  96. ncbi Membrane excitability of wing and rod cells in frog taste discs following denervation
    Kazuhisa Okuda-Akabane
    Department of Oral Physiology, School of Dentistry, Iwate Medical University, Morioka 020 8505, Japan
    Brain Res 1103:145-9. 2006
    ..Here we report that the shapes of wing and rod cells isolated from taste discs in the bullfrog (Rana catesbeiana) remained unchanged 1 month after cutting bilateral glossopharyngeal nerves...
  97. ncbi Molecular cloning of bullfrog prolactin receptor cDNA: changes in prolactin receptor mRNA level during metamorphosis
    Itaru Hasunuma
    Department of Biology, School of Education, Waseda University, Nishiwaseda 1 6 1, Shinjuku ku, Tokyo 169 8050, Japan
    Gen Comp Endocrinol 138:200-10. 2004
    ..The results support the view that PRL in larval period acts not only on the larval organs but also on the organs that are necessary for the adult life to maintain or develop their structures and functions...
  98. ncbi Cloning and characterization of a functional P2X receptor from larval bullfrog skin
    P J Jensik
    Department of Physiology, Southern Illinois University School of Medicine, Carbondale, Illinois 62901, USA
    Am J Physiol Cell Physiol 281:C954-62. 2001
    ATP activates an apical-to-basolateral nonselective cation current across the skin of larval bullfrogs (Rana catesbeiana) with similarities to currents carried by some P2X receptors...
  99. ncbi Development of aldosterone-stimulation of short-circuit current across larval frog skin
    S D Hillyard
    Department of Biology, University of Nevada, Las Vegas 89154
    J Comp Physiol B 161:257-63. 1991
    ..l-1 triiodothyronine (T3). Aldosterone treatment of these tissues resulted in a significant increase in Na+ channel density...
  100. ncbi Action of perchlorate on the voltage dependent inactivation of excitation-contraction coupling in frog skeletal muscle fibres
    Nazira Piriz
    Departamento de Biofisica, Facultad de Medicina, Universidad de la Republica, Gral Flores 2125, Montevideo, Uruguay
    J Muscle Res Cell Motil 28:315-28. 2007
    ..The negative shift in the steady state inactivation of Q(1) correlated well with the effect on Ca(2+) release...
  101. ncbi Effects of medullary Raphé stimulation on fictive lung ventilation during development in Rana catesbeiana
    Olivier Belzile
    Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9039, USA
    J Exp Biol 210:2046-56. 2007
    ..We conclude that, in this preparation, stimulation of lung ventilation by the medullary Raphé is restricted to early (pre-metamorphic) stages...

Research Grants86

  1. MECHANISMS OF THYROID HORMONE ACTION IN DEVELOPMENT
    VALERIE GALTON; Fiscal Year: 1991
    ..between hormone metabolism, hormone-receptor interactions and hormone action in developing amphibian species: Rana catesbeiana and Ambystoma mexicanum...
  2. Thyroid hormone action in the developing eye
    Mark Schneider; Fiscal Year: 2002
    ..it is essential for all post-embryonic stages of development and metamorphosis, and in this laboratory the Rana catesbeiana (RC) tadpole has proved to be an excellent vertebrate model in which to study the actions of TH in ..
  3. Thyroid hormone action in the developing eye
    Mark Schneider; Fiscal Year: 2003
    ..it is essential for all post-embryonic stages of development and metamorphosis, and in this laboratory the Rana catesbeiana (RC) tadpole has proved to be an excellent vertebrate model in which to study the actions of TH in ..
  4. Central Respiratory Chemoreception in the Amphibian
    DEBORA ZAMORA; Fiscal Year: 2007
    ..contribute to the understanding of central respiratory chemoreceptor function and development in the larval Rana catesbeiana brainstem...
  5. NEUROETHOLOGY OF VOCAL COMMUNICATION
    Andrea Simmons; Fiscal Year: 2006
    ..abstract_text> ..
  6. STRUCTURE AND DIVERSITY IN THE IMMUNE SYSTEM
    Lisa Steiner; Fiscal Year: 1980
    ..We wish to determine major structural features of the various immunoglobulins in the bullfrog, Rana catesbeiana, especially to determine similarities and differences from mammalian immunoglobulins...
  7. SENSORY NEURON ADDITION IN RAT
    PAUL FAREL; Fiscal Year: 2002
    ..We will also determine whether the presumed population of type-L neurons differs from nature sensory neurons in the functional differentiation. ..
  8. Hair-Bundle Lipids
    Peter Gillespie; Fiscal Year: 2009
    ..Together, the experiments in this proposal will allow us to determine how lipids regulate transduction and adaptation. ..
  9. ROLE OF CALCIUM PUMPING IN HAIR-BUNDLE FUNCTION
    Peter Gillespie; Fiscal Year: 2004
    ..If re-expression of PMCA2 in hair cells rescues auditory function in these otherwise PMCA2-deficient mice, the key location of PMCA2 in the ear must be the hair cell. ..
  10. Quantifying Hair Bundle Components
    Peter Gillespie; Fiscal Year: 2007
    ..This project is an essential first step in understanding what makes up a hair bundle. ..
  11. Gene expression in regenerating adult vertebrate CNS.
    Judith Chapman; Fiscal Year: 2006
    ..Genes will be compared with those implicated in normal development and with models incapable of CNS regeneration. ..
  12. Excitation-Contraction Coupling in Dystrophic Muscle
    JULIO VERGARA; Fiscal Year: 2007
    ....
  13. Insight from Lamprey Genome: Structure-Function studies of Novel GnRH Receptors
    STACIA SOWER; Fiscal Year: 2007
    ..Studying the lamprey genome is a touchstone for understanding genes that arose in the vertebrates and offers an innovative approach to therapeutic research. ..
  14. HAIR CELL RESPONSES TO OTOTOXIC DRUGS
    Peter S Steyger; Fiscal Year: 2010
    ..The proposed research will enable us to develop strategies to prevent the entry of aminoglycosides into the inner ear fluids and therefore ototoxic sequelae, particularly life-long deafness, tinnitus and vestibular deficits. ..
  15. Role of the Transverse Tubular System in Mammalian Skeletal Muscle Excitability
    JULIO VERGARA; Fiscal Year: 2007
    ....
  16. Expression of KCC4 in distal colon surface epithelia
    COLLEEN TALBOT; Fiscal Year: 2006
    ..It is anticipated that a long-term collaboration will be established between the Fellow and the Sponsor, further helping to track these students to research careers at a major doctoral granting institution. ..
  17. HAIR CELL RESPONSES TO OTOTOXIC DRUGS
    PETER STEYGER; Fiscal Year: 2009
    ..abstract_text> ..
  18. Hair-Bundle Lipids
    Peter Gillespie; Fiscal Year: 2009
    ..Together, the experiments in this proposal will allow us to determine how lipids regulate transduction and adaptation. ..
  19. Hair-Bundle Proteins
    Peter Gillespie; Fiscal Year: 2009
    ..The complex of proteins in hair cells that transduce sound are still largely unknown; the goal of this project is to identify and characterize them, as they are essential for hearing. ..
  20. Hair-Bundle Proteins
    Peter Gillespie; Fiscal Year: 2007
    ..The complex of proteins in hair cells that transduce sound are still largely unknown; the goal of this project is to identify and characterize them, as they are essential for hearing. ..