Summary: An organophosphate cholinesterase inhibitor that is used as an insecticide. It has low mammalian toxicity. (From Merck Index, 11th ed)

Top Publications

  1. Mullens B, Velten R, Hinkle N, Kuney D, Szijj C. Acaricide resistance in northern fowl mite (Ornithonyssus sylviarum) populations on caged layer operations in Southern California. Poult Sci. 2004;83:365-74 pubmed
    ..and commercial formulations of malathion, carbaryl (Sevin), permethrin, and a commercial formulation of tetrachlorvinphos/dichlorvos (Ravap) were tested...
  2. Hamm R, Kaufman P, Reasor C, Rutz D, Scott J. Resistance to cyfluthrin and tetrachlorvinphos in the lesser mealworm, Alphitobius diaperinus, collected from the eastern United States. Pest Manag Sci. 2006;62:673-7 pubmed
    ..The toxicity of cyfluthrin and tetrachlorvinphos to five strains of the lesser mealworm was compared with the toxicity to a susceptible laboratory strain...
  3. Davis M, Boone J, Moran J, Tyler J, Chambers J. Assessing intermittent pesticide exposure from flea control collars containing the organophosphorus insecticide tetrachlorvinphos. J Expo Sci Environ Epidemiol. 2008;18:564-70 pubmed publisher
    ..1; 22 in study 2) of different breeds and weights were treated with over-the-counter flea collars containing tetrachlorvinphos (TCVP)...
  4. Nayudu P, Kiesel P, Nowshari M, Hodges J. Abnormal in vitro development of ovarian follicles explanted from mice exposed to tetrachlorvinphos. Reprod Toxicol. 1994;8:261-8 pubmed
    ..from 22- to 24-day-old mice during a period when the colony was being treated for skin parasites with tetrachlorvinphos (TCVP) (Rabond)...
  5. Karanth S, Pope C. In vitro inhibition of blood cholinesterase activities from horse, cow, and rat by tetrachlorvinphos. Int J Toxicol. 2003;22:429-33 pubmed
    The organophosphorus insecticide tetrachlorvinphos (TCVP) is commonly used as a feed-through larvicide in many livestock species, including cattle and horses...
  6. Sengul M, Kaçar N, Karaca M, Öner S, Ergin C. [A case with scalp pruritus caused by Dermanysus gallinae (order: mesostigmata)]. Mikrobiyol Bul. 2017;51:293-298 pubmed publisher
    ..For environmental sanitation, carbamates (such as carbolineum, trichlorfon, malathion, tetrachlorvinphos, etc...
  7. Singh N, Johnson D. Baseline Susceptibility and Cross-Resistance in Adult and Larval Alphitobius diaperinus (Coleoptera: Tenebrionidae) Collected from Poultry Farms in Arkansas. J Econ Entomol. 2015;108:1994-9 pubmed publisher
    ..A probit analysis suggested the M population to be resistant to cyfluthrin and tetrachlorvinphos, while the S population was susceptible to both compounds...
  8. Fu L, Lu X, Tan J, Wang L, Chen J. Multiresidue determination and potential risks of emerging pesticides in aquatic products from Northeast China by LC-MS/MS. J Environ Sci (China). 2018;63:116-125 pubmed publisher
    ..were present in the fish samples; however, their levels were low, except for atrazine, linuron, ethoprophos, tetrachlorvinphos, acetochlor and fenthion...
  9. Rust M, Vetter R, Denholm I, BLAGBURN B, Williamson M, Kopp S, et al. Susceptibility of Adult Cat Fleas (Siphonaptera: Pulicidae) to Insecticides and Status of Insecticide Resistance Mutations at the Rdl and Knockdown Resistance Loci. Parasitol Res. 2015;114 Suppl 1:S7-18 pubmed publisher
    ..LD50 values for tetrachlorvinphos ranged from 20.0 to 420.0 ng/flea...

More Information


  1. James P, Meade R, Powell D. Effect of insecticidal ear tags on populations of lice (Damalinia ovis) infesting sheep. Aust Vet J. 1989;66:134-7 pubmed
    Polymer matrix ear tags containing 13.7% w/w tetrachlorvinphos or 8.5% w/w cypermethrin were applied to Merino wethers infested with lice and carrying two months wool...
  2. Gromysz Kałkowska K, Szubartowska E. Toxicity of tetrachlorvinphos to Rana temporaria L. Comp Biochem Physiol C. 1993;105:285-90 pubmed
    ..4. The relatively high susceptibility of frogs to intoxication with tetrachlorwinfos is probably the result of a high affinity of cholinesterase to this pesticide, because of the presence of the P = O bond in its molecule. ..
  3. Marçon P, Thomas G, Siegfried B, Campbell J. Susceptibility of stable flies (Diptera:Muscidae) from southeastern Nebraska beef cattle feedlots to selected insecticides and comparison of 3 bioassay techniques. J Econ Entomol. 1997;90:293-8 pubmed
  4. Berger J, Valdez S, Puschner B, Leutenegger C, Gardner I, Madigan J. Effects of oral tetrachlorvinphos fly control (Equitrol) administration in horses: physiological and behavioural findings. Vet Res Commun. 2008;32:75-92 pubmed
    ..The organophosphorus (OP) insecticide tetrachlorvinphos (TCVP) is used as a feed-through larvicide to prevent completion of the fly larval life cycle in horse ..
  5. Groisman L, Rav Acha C, Gerstl Z, Mingelgrin U. Sorption and detoxification of toxic compounds by a bifunctional organoclay. J Environ Qual. 2004;33:1930-6 pubmed
    ..for two organophosphate pesticides, methyl parathion [O,O-dimethyl O-(p-nitrophenyl) thionophosphate] and tetrachlorvinphos [2-chloro-1-(2,4,5-trichlorophenyl)ethenyl dimethyl phosphate], was demonstrated...
  6. Rassette M, Pierpont E, Wahl T, Berres M. Use of Beauveria bassiana to control northern fowl mites (Ornithonyssus sylviarum) on roosters in an agricultural research facility. J Am Assoc Lab Anim Sci. 2011;50:910-5 pubmed
    ..compared with water (30 mL, control), and Beauveria compared with the common topical organophosphate agent tetrachlorvinphos-dichlorvos (30 mL). We also assessed a higher dose of Beauveria (300 mL, 2...
  7. Myers C, Aleman M, Heidmann R, Wilson W, Madigan J. Myopathy in American miniature horses. Equine Vet J. 2006;38:272-6 pubmed
  8. Ortiz Hernández M, Quintero Ramírez R, Nava Ocampo A, Bello Ramírez A. Study of the mechanism of Flavobacterium sp. for hydrolyzing organophosphate pesticides. Fundam Clin Pharmacol. 2003;17:717-23 pubmed
    ..of the following organophosphate pesticides was experimentally and theoretically studied: phorate, tetrachlorvinphos, methyl-parathion, terbufos, trichloronate, ethoprophos, phosphamidon, fenitrothion, dimethoate and DEF...
  9. Marçon P, Thomas G, Siegfried B, Campbell J, Skoda S. Resistance status of house flies (Diptera: Muscidae) from southeastern Nebraska beef cattle feedlots to selected insecticides. J Econ Entomol. 2003;96:1016-20 pubmed
    ..Probable explanations for the resistance status of these house fly populations and implications for global feedlot fly management are discussed. ..
  10. Settimi L, Costellati L, Naldi M, Bersani G, Olanda S, Maiozzi P. Mortality among workers in an Italian cigarette factory. Occup Med (Lond). 1999;49:361-4 pubmed
    ..1; CI = 2.2-21.0). Although based on small numbers, the excess of NHL here reported suggests that potential exposure to foliar residues of pesticides should be thoroughly considered in tobacco manufacturing. ..
  11. James P, Mitchell H, Cockrum K, Ancell P. Controlled release insecticide devices for protection of sheep against head strike caused by Lucilia cuprina. Vet Parasitol. 1994;52:113-28 pubmed
    The effectiveness of polymer matrix tags containing (w/w) 8.5% cypermethrin, 7.5% flucythrinate, 13.7% tetrachlorvinphos or 20...
  12. Wang J, McCommas S, Syvanen M. Molecular cloning of a glutathione S-transferase overproduced in an insecticide-resistant strain of the housefly (Musca domestica). Mol Gen Genet. 1991;227:260-6 pubmed
    ..domestica; (2) the natural variant Cornell-R overproduces excess transcript from two and probably more of these genes; and (3) the unstable mutation in Cornell-R influences the levels of multiple GSTs. ..
  13. Hogsette J, Prichard D, Ruff J. Economic effects of horn fly (Diptera: Muscidae) populations on beef cattle exposed to three pesticide treatment regimes. J Econ Entomol. 1991;84:1270-4 pubmed
    ..Spray treatments providing the best fly control were Lintox-D and Ra-Vap. The most economical products for use were Del-Tox, Lintox-D, and Ra-Vap. ..
  14. Amer S, Aly F. Cytogenetic effects of pesticides. IV. Cytogenetic effects of the insecticides Gardona and Dursban. Mutat Res. 1992;279:165-70 pubmed
    ..2 +/- 0.19/cell and 7.6 +/- 0.15/cell in the solvent control. The presented results indicate that both Gardona and Dursban in the tested concentrations are mutagenic in mouse spleen cell cultures. ..
  15. Kaufman P, Strong C, Rutz D. Susceptibility of lesser mealworm (Coleoptera: Tenebrionidae) adults and larvae exposed to two commercial insecticides on unpainted plywood panels. Pest Manag Sci. 2008;64:108-11 pubmed
    ..mealworms, Alphitobius diaperinus (Panzer), to two commercially formulated insecticides, cyfluthrin and tetrachlorvinphos, were examined through exposure on treated plywood panels...
  16. Mullens B, Owen J, Kuney D, Szijj C, Klingler K. Temporal changes in distribution, prevalence and intensity of northern fowl mite (Ornithonyssus sylviarum) parasitism in commercial caged laying hens, with a comprehensive economic analysis of parasite impact. Vet Parasitol. 2009;160:116-33 pubmed publisher
    ..The results were related to other studies of mite impact on domestic hens and to wild bird-ectoparasite studies. Much of the mite economic damage probably is due to engaging and maintaining the immune response. ..
  17. Yañez Ocampo G, Sanchez Salinas E, Ortiz Hernández M. Removal of methyl parathion and tetrachlorvinphos by a bacterial consortium immobilized on tezontle-packed up-flow reactor. Biodegradation. 2011;22:1203-13 pubmed publisher
    ..reactor (TPUFR) with an immobilized bacterial consortium for biological treatment of methyl-parathion and tetrachlorvinphos was evaluated...
  18. Guyton K, Loomis D, Grosse Y, El Ghissassi F, Benbrahim Tallaa L, Guha N, et al. Carcinogenicity of tetrachlorvinphos, parathion, malathion, diazinon, and glyphosate. Lancet Oncol. 2015;16:490-1 pubmed publisher